3,089 results match your criteria BMC pediatrics[Journal]


Associations between objective measures of physical activity, sleep and stress levels among preschool children.

BMC Pediatr 2020 May 27;20(1):258. Epub 2020 May 27.

Research Unit for Dietary Studies, The Parker Institute, Bispebjerg and Frederiksberg Hospital, The Capital Region, Frederiksberg, Denmark.

Background: Cortisol is often used as a biological marker for stress. When measured in urine or serum, representing a short-term measurement of the hormone, it has been associated with unfavorable sleep characteristics and both low and high physical activity levels. However, cortisol in hair represents a long-term stress measure and has been suggested as a promising new marker for chronic stress. Read More

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http://dx.doi.org/10.1186/s12887-020-02108-7DOI Listing

Prevalence of pneumonia and its associated factors among under-five children in East Africa: a systematic review and meta-analysis.

BMC Pediatr 2020 May 27;20(1):254. Epub 2020 May 27.

Department of Nursing, College of Health Sciences, Woldia University, P.O.Box 400, Woldia, Ethiopia.

Background: Pneumonia is defined as an acute inflammation of the Lungs' parenchymal structure. It is a major public health problem and the leading cause of morbidity and mortality in under-five children especially in developing countries. In 2015, it was estimated that about 102 million cases of pneumonia occurred in under-five children, of which 0. Read More

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http://dx.doi.org/10.1186/s12887-020-02083-zDOI Listing

Development and validation of bile acid profile-based scoring system for identification of biliary atresia: a prospective study.

BMC Pediatr 2020 May 27;20(1):255. Epub 2020 May 27.

Department of Neonatology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, 1665 Kong Jiang Road, Shanghai, 200092, China.

Background: Early distinguishing biliary atresia from other causes of infantile cholestasis remains a major challenge. We aimed to develop and validate a scoring system based on bile acid for identification of biliary atresia.

Methods: In a prospective study, a total of 141 infants with cholestasis were enrolled in two sets (derivation cohort, n = 66; validation cohort, n = 75) from 2014 to 2018. Read More

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http://dx.doi.org/10.1186/s12887-020-02169-8DOI Listing

A cost-of-illness analysis of β-Thalassaemia major in children in Sri Lanka - experience from a tertiary level teaching hospital.

BMC Pediatr 2020 May 27;20(1):257. Epub 2020 May 27.

Liverpool School of Tropical Medicine, Liverpool, UK.

Background: Sri Lanka has a high prevalence of β-thalassaemia major. Clinical management is complex and long-term and includes regular blood transfusion and iron chelation therapy. The economic burden of β-thalassaemia for the Sri Lankan healthcare system and households is currently unknown. Read More

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http://dx.doi.org/10.1186/s12887-020-02160-3DOI Listing

Clinical manifestations and associated disorders in children with celiac disease in southern Iran.

BMC Pediatr 2020 May 27;20(1):256. Epub 2020 May 27.

Shiraz Endocrinology and Metabolism Research Center, Shiraz University of Medical Sciences, P.O. Box: 71345-1744, Shiraz, Iran.

Background: Celiac disease (CD) is an immune mediated inflammatory enteropathy, triggered by gluten exposure in HLA-DQ2 and/or -DQ8 genetics. The presentation of celiac disease in children is changing, with increase in non-classical symptoms. We aim to evaluate the clinical presentations of celiac disease amongst children, diagnosed with CD. Read More

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http://dx.doi.org/10.1186/s12887-020-02162-1DOI Listing

Normative values for circulating intestinal fatty acid binding protein and calprotectin across gestational ages.

BMC Pediatr 2020 May 26;20(1):250. Epub 2020 May 26.

Department of Pediatrics, Division of Cardiology, Johns Hopkins School of Medicine, 720 Rutland Ave, Ross 1143, Baltimore, MD, 21205, USA.

Background: Necrotizing enterocolitis (NEC) is associated with significant morbidity and mortality. Serum biomarkers to aid diagnosis, such as intestinal fatty acid binding protein (IFABP) and calprotectin, are actively being investigated; however, the normative values of these markers among healthy premature and term infants remains unknown. We sought to identify normative values for the serum concentrations of IFABP and calprotectin across gestational (GA) and post-menstrual age. Read More

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http://dx.doi.org/10.1186/s12887-020-02142-5DOI Listing

Swedish translation and validation of the Pediatric Insomnia Severity Index.

BMC Pediatr 2020 May 26;20(1):253. Epub 2020 May 26.

Department of Pediatric Dentistry, Institute for Postgraduate Dental Education, Jönköping, Sweden.

Background: To increase health and well-being in young children, it is important to acknowledge and promote the child's sleep behaviour. However, there is a lack of brief, validated sleep screening instruments for children. The aims of the study were to (1) present a Swedish translation of the PISI, (2) examine the factor structure of the Swedish version of PISI, and test the reliability and validity of the PISI factor structure in a sample of healthy children in Sweden. Read More

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http://dx.doi.org/10.1186/s12887-020-02150-5DOI Listing

A concept analysis of children with complex health conditions: implications for research and practice.

BMC Pediatr 2020 May 26;20(1):251. Epub 2020 May 26.

Faculty of Science, University of Prince Edward Island, 550 University Avenue, Charlottetown, Prince Edward Island, C1A 4P3, Canada.

Background: This concept analysis aimed to clarify the meaning of "children with complex health conditions" and endorse a definition to inform future research, policy, and practice.

Methods: Using Walker and Avant's (2011)'s approach, we refined the search strategy with input from our team, including family representatives. We reviewed the published and grey literature. Read More

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http://dx.doi.org/10.1186/s12887-020-02161-2DOI Listing

Enteroviral and herpes simplex virus central nervous system infections in infants < 90 days old: a Paediatric Investigators' Collaborative Network on Infections in Canada (PICNIC) study.

BMC Pediatr 2020 May 26;20(1):252. Epub 2020 May 26.

Department of Pediatrics, University of Alberta, 4-590 ECHA, 11405-87 Ave, Edmonton, AB, T6G 1C9, Canada.

Background: The relative contribution of viruses to central nervous system (CNS) infections in young infants is not clear. For viral CNS infections, there are limited data on features that suggest HSV etiology or on predictors of unfavorable outcome.

Methods: In this cross-sectional retrospective study, seven centers from the Pediatric Investigators Collaborative Network on Infections in Canada identified infants < 90 days of age with CNS infection proven to be due to enterovirus (EV) or herpes simplex virus (HSV) January 1, 2013 through December 31, 2014. Read More

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http://dx.doi.org/10.1186/s12887-020-02151-4DOI Listing

Severe acute malnutrition and its associated factors among children under-five years: a facility-based cross-sectional study.

BMC Pediatr 2020 May 26;20(1):249. Epub 2020 May 26.

Partnership for Social Development, Kathmandu, 446006, Nepal.

Background: Despite consistent efforts to enhance child nutrition, poor nutritional status of children continues to be a major public health problem in Nepal. This study identified the predictors of severe acute malnutrition (SAM) among children aged 6 to 59 months in the two districts of Nepal.

Methods: We used data from a cross-sectional study conducted among 6 to 59 months children admitted to the Outpatient Therapeutic Care Centers (OTCC). Read More

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http://dx.doi.org/10.1186/s12887-020-02154-1DOI Listing

Risk factors for readmission for phototherapy due to jaundice in healthy newborns: a retrospective, observational study.

BMC Pediatr 2020 May 26;20(1):248. Epub 2020 May 26.

Department of Neonatology, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, 6 Weizmann St, 6423906, Tel Aviv, Israel.

Background: The guidelines of the American Academy of Pediatrics (AAP) for monitoring neonatal jaundice recommend universal postnatal screening for hyperbilirubinemia within 48 h from discharge. We observed that neonate with low-risk jaundice were more likely to be readmitted to hospital for phototherapy compared to neonate with high-risk jaundice. The aim of this study was to identify additional factors that increase the risk for jaundice-related readmission. Read More

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http://dx.doi.org/10.1186/s12887-020-02157-yDOI Listing

Anxiety related disorders in adolescents in the United Arab Emirates: a population based cross-sectional study.

BMC Pediatr 2020 May 25;20(1):245. Epub 2020 May 25.

University of Sharjah, Sharjah, UAE.

Background: Anxiety disorders are common among children and adolescents. However, there is a paucity of up-to-date data on the prevalence and correlates of anxiety-related disorders among children and adolescents in the United Arab Emirates (UAE).

Methods: We conducted a cross sectional study to determine the prevalence of specific anxiety-related disorders (e. Read More

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http://dx.doi.org/10.1186/s12887-020-02155-0DOI Listing
May 2020
1.918 Impact Factor

Clustering of health-related behaviours and its relationship with individual and contextual factors in Portuguese adolescents: results from a cross-sectional study.

BMC Pediatr 2020 May 25;20(1):247. Epub 2020 May 25.

Escola Nacional de Saúde Pública, Universidade NOVA de Lisboa, Avenida Padre Cruz, 1600-560, Lisbon, Portugal.

Background: Health behaviours are shaped early in life and tend to occur in complex specific patterns. We aimed to characterise these patterns among Portuguese adolescents and their association with individual and contextual factors.

Methods: This study was based in the Portuguese 2009/10 survey of Health Behaviour in School-Aged Children Study, comprising 4036 adolescents. Read More

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http://dx.doi.org/10.1186/s12887-020-02057-1DOI Listing

CYP and SXR gene polymorphisms influence in opposite ways acute rejection rate in pediatric patients with renal transplant.

BMC Pediatr 2020 May 25;20(1):246. Epub 2020 May 25.

Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico UOC Nefrologia Dialisi e Trapianto pediatrico, Via della, Commenda 9, 20122, Milan, Italy.

Background: We evaluated the role of CYP3A5, ABCB1 and SXR gene polymorphisms in the occurrence of acute kidney rejection in a cohort of pediatric renal transplant recipients.

Methods: Forty-nine patients were genotyped for CYP3A5, ABCB1 and SXR polymorphisms and evaluated with tacrolimus through levels in a retrospective monocenter study.

Results: Patients with the A allele of CYP3A5 treated with tacrolimus had a higher risk of acute rejection than those without the A allele, while patients carrying the homozygous GG variant for SXR A7635GG did not show any episode of acute rejection. Read More

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http://dx.doi.org/10.1186/s12887-020-02152-3DOI Listing

Parents' experiences of accessing respite care for children with Autism Spectrum Disorder (ASD) at the acute and primary care interface: a systematic review.

BMC Pediatr 2020 May 22;20(1):244. Epub 2020 May 22.

Trinity College Dublin, Dublin, Ireland.

Background: Population prevalence estimates by the World Health Organisation suggest that 1 in 160 children worldwide has an Autism Spectrum Disorder (ASD). Accessing respite care services for children with an ASD can often be a daunting and exhaustive process, with parents sometimes forced to access acute hospital services as an initial point of contact for respite care or in a crisis situation. To gain an in-depth understanding of accessing respite care for children with an ASD, from the perspectives of parents, a systematic review of the evidence on parent's experiences and views of respite care for children with an ASD at the acute and primary interface was undertaken. Read More

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http://dx.doi.org/10.1186/s12887-020-02045-5DOI Listing

Pulmonary hypertension in late-onset Methylmalonic Aciduria and Homocystinemia: a case report.

BMC Pediatr 2020 May 22;20(1):243. Epub 2020 May 22.

Department of Cardiology, Key Laboratory of Birth Defects and Related Diseases of Women and Children of Ministry of Education, West China Second University Hospital, Sichuan University, 20# Section 3 South Renmin Road, Chengdu, Sichuan, China.

Background: Methylmalonic Aciduria and Homocystinemia, cobalamin C (cblC) is an inherited disease of vitamin B metabolism with a wide spectrum of clinical manifestations. cblC presenting with pulmonary hypertension (PH) as leading sympotom is rare and easily misdiagnosed because of limited awareness. Timely diagnosis is crucial by the relentless progression without appropriate treatment. Read More

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http://dx.doi.org/10.1186/s12887-020-02130-9DOI Listing

Influence of time under mechanical ventilation on bronchopulmonary dysplasia severity in extremely preterm infants: a pilot study.

BMC Pediatr 2020 May 21;20(1):241. Epub 2020 May 21.

Postgraduation Program in Rehabilitation Sciences UEL-UNOPAR, Londrina State University (UEL), Londrina, PR, Brazil.

Background: The relation between mechanical ventilation (MV) and bronchopulmonary dysplasia (BPD) - a common disease in extremely premature newborn (PTNB) - is well stabilished, but is unknown, however, how much time under MV influences the severity of the disease.

Aim: To define the duration under MV with greater chance to develop moderate to severe BPD in extremely PTNB and to compare clinical outcomes before and during hospitalization among patients with mild and moderate to severe BPD.

Methods: Fifty-three PTNB were separated into mild and moderate to severe BPD groups and their data were analyzed. Read More

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http://dx.doi.org/10.1186/s12887-020-02129-2DOI Listing

A systematic review to assess the effectiveness of technology-based interventions to address obesity in children.

BMC Pediatr 2020 May 22;20(1):242. Epub 2020 May 22.

Institute for Global Food Security (Centre for Public Health), Grosvenor Road, Belfast, BT12 6BJ, UK.

Background: Childhood obesity is associated with a multitude of co-morbidities, including hypertension, hyperlipidaemia, cardiovascular disease and type 2 diabetes. Childhood obesity can also affect a young person's social, emotional and mental health if they encounter negative prejudice and social marginalisation. Given the prevalence of overweight and obese children globally, it is imperative that effective interventions are developed. Read More

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http://dx.doi.org/10.1186/s12887-020-02081-1DOI Listing

Right ventricular function among South East Nigeria children with sickle cell anaemia.

BMC Pediatr 2020 May 21;20(1):240. Epub 2020 May 21.

Department of Paediatrics, College of Medicine, University of Nigeria Enugu Campus, Enugu, Nigeria.

Background: Sickle cell anaemia (SCA) is characterized by attendant ischemia-reperfusion injury especially to the heart.

Methods: The aim of this work is to compare the right ventricular function of children with SCA in steady state (subjects) with those with haemoglobin AA genotype (controls), using echocardiography. It is a cross-sectional study, which echocardiographic measurements to assess right ventricular function among children with SCA and their controls. Read More

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http://dx.doi.org/10.1186/s12887-020-02143-4DOI Listing

Factors affecting tracheostomy in critically ill paediatric patients in Japan: a data-based analysis.

BMC Pediatr 2020 May 20;20(1):237. Epub 2020 May 20.

Department of Emergency and Critical Care Medicine, Juntendo University, Urayasu Hospital, Urayasu-city, Chiba, Japan.

Background: There has been an increasing number of children surviving with high medical needs, for whom tracheostomy and/or home ventilation is part of their chronic disease management. The purpose of this study was to describe the indications, epidemiology, frequency, and associated factors for tracheostomy in critically ill paediatric patients using the data available in the Japanese Registry of Paediatric Acute Care (JaRPAC).

Methods: This multicentre epidemiologic study collected data concerning paediatric tracheostomy from the JaRPAC database. Read More

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http://dx.doi.org/10.1186/s12887-020-02144-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237622PMC

Socio-demographic, environmental and behavioural risk factors of diarrhoea among under-five children in rural Ethiopia: further analysis of the 2016 Ethiopian demographic and health survey.

BMC Pediatr 2020 May 20;20(1):239. Epub 2020 May 20.

Department of Statistics, College of Natural and Computational Science, University of Gondar, Gondar, Ethiopia.

Background: Diarrhoea is one of the major contributors to death among under-five children in Ethiopia. Studies conducted in different countries showed that rural children are more severely affected by diarrhoea than urban children. Thus, this study was aimed to identify the socio-demographic, environmental and behavioural associated risk factors of the occurrence of diarrhoea among under-five children in rural Ethiopia. Read More

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http://dx.doi.org/10.1186/s12887-020-02141-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238554PMC

Derivation and validation of a prognostic score for neonatal mortality in Ethiopia: a case-control study.

BMC Pediatr 2020 May 20;20(1):238. Epub 2020 May 20.

Department of Pediatrics, Stanford University School of Medicine, Division of Critical Care, Stanford, California, USA.

Background: Early warning scores for neonatal mortality have not been designed for low income countries. We developed and validated a score to predict mortality upon admission to a NICU in Ethiopia.

Methods: We conducted a retrospective case-control study at the University of Gondar Hospital, Gondar, Ethiopia. Read More

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http://dx.doi.org/10.1186/s12887-020-02107-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237621PMC

Prevalence and associated factors of acute diarrhea among under-five children in Kamashi district, western Ethiopia: community-based study.

BMC Pediatr 2020 May 19;20(1):236. Epub 2020 May 19.

Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Background: Diarrheal diseases are the second major cause of death among under-five children globally. It kills about 2.5 million people each year, with 60-70% of them being children under 5 years of age. Read More

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http://dx.doi.org/10.1186/s12887-020-02138-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236964PMC

Donor human milk programs in German, Austrian and Swiss neonatal units - findings from an international survey.

BMC Pediatr 2020 May 19;20(1):235. Epub 2020 May 19.

Department of Womens' and Children's Health, Division of Neonatology, University Children's Hospital, Leipzig, Germany.

Background: Donor human milk (DHM) has been recommended for premature infants if mothers' own milk is not available. The aim of this study was to increase the knowledge about the utilization rate and handling of DHM among neonatal units in Germany, Austria und Switzerland.

Methods: Online survey of utilization rates and handling practices of DHM of all neonatal units within Germany, Austria and Switzerland providing care for premature infants less than 32 weeks of gestation. Read More

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http://dx.doi.org/10.1186/s12887-020-02137-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236941PMC

Stunting diagnostic and awareness: impact assessment study of sociodemographic factors of stunting among school-going children of Pakistan.

BMC Pediatr 2020 May 19;20(1):232. Epub 2020 May 19.

School of Electrical Engineering and Computer Science, National University of Sciences and Technology, H/12 sector, Islamabad, Pakistan.

Background: Stunting is a major public health issue in most of developing countries. Although, its worldwide prevalence is decreasing slowly but the number of stunted children is still rising in Pakistan. Stunting is highly associated with several long-term consequences, including higher rate of mortality and morbidity, deficient cognitive growth, school performance, learning capacity, work capacity and work productivity. Read More

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http://dx.doi.org/10.1186/s12887-020-02139-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236201PMC

Microbiological analyses of nasally guided catheters after less invasive surfactant administration - a pilot study.

BMC Pediatr 2020 May 19;20(1):234. Epub 2020 May 19.

Department of Neonatology, University Children's Hospital Tübingen, Tübingen, Germany.

Background: Respiratory distress syndrome (RDS) is a frequent complication of premature birth. Treating RDS by continuous positive airway pressure and less invasive surfactant administration (LISA) may reduce bronchopulmonary dysplasia. Surfactant, however, can be inactivated by bacterial infection. Read More

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http://dx.doi.org/10.1186/s12887-020-02147-0DOI Listing

Survival status and mortality predictors among severely malnourished under 5 years of age children admitted to Minia University maternity and children hospital.

BMC Pediatr 2020 May 19;20(1):233. Epub 2020 May 19.

Public Health and Preventive Medicine department, Faculty of medicine, El-Minia University. University St, El-Minia, 1666, Egypt.

Background: Though effective treatment programs for severely malnourished children are available, mortality rate among children with acute malnutrition continue to rise and little is known about its long-term outcomes and potential predictors of its in-hospital and post-discharge mortality. The aim of this study was to assess the survival status and predictors for mortality in severely malnourished children admitted to Minia University Maternity and Children Hospital.

Methods: A retrospective cohort study which included 135 children under 5 years of age who were admitted to the nutrition rehabilitation ward with severe acute malnutrition (SAM) during the period from January to December 2018. Read More

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http://dx.doi.org/10.1186/s12887-020-02146-1DOI Listing

Determinants of road traffic injuries in Iranian children; results from a National Representative Demographic- Health Survey 2010.

BMC Pediatr 2020 May 19;20(1):231. Epub 2020 May 19.

Social Determinants of Health Research Center, Saveh University of Medical Sciences, Saveh, Iran.

Background: Road Traffic Injuries (RTIs) are a leading cause of disabilities and mortalities in Iran. The occurrence of RTIs among children is increasing. This study aims are to assess RTIs among Iranian children and to determine the main socio-economics determinants. Read More

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http://dx.doi.org/10.1186/s12887-020-02127-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236294PMC

Chest CT imaging characteristics of COVID-19 pneumonia in preschool children: a retrospective study.

BMC Pediatr 2020 05 18;20(1):227. Epub 2020 May 18.

Huaxi MR Research Center (HMRRC), Functional and molecular imaging Key Laboratory of Sichuan Province, Department of Radiology, West China Hospital of Sichuan University, No. 37 Guo Xue Xiang, Chengdu, 610041, Sichuan, PR China.

Background: Recently, the World Health Organization has declared the coronavirus disease 2019 (COVID-19) outbreak a public health emergency of international concern. So far, however, limited data are available for children. Therefore, we aimed to investigate the clinical and chest CT imaging characteristics of COVID-19 in preschool children. Read More

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http://dx.doi.org/10.1186/s12887-020-02140-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232932PMC
May 2020
1.918 Impact Factor

Concurrent diabetic ketoacidosis and pancreatitis in Paediatric acute lymphoblastic leukemia receiving L-asparaginase.

BMC Pediatr 2020 May 18;20(1):228. Epub 2020 May 18.

Department of Paediatrics, Jawaharlal Nehru Medical College, Sawangi Meghe, Wardha, India.

Background: Although hyperglycemia and pancreatitis are known side effects of L-asparaginase, both contributing to the development of diabetic ketoacidosis (DKA) is unfamiliar in literature.

Case Presentation: We report a case of an adolescent girl, recently diagnosed with ALL, who presented with pain in abdomen and breathing difficulty following chemotherapy with L-asparaginase. On subsequent evaluation, she was found to have high anion gap metabolic acidosis, hyperglycemia and ketonuria. Read More

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http://dx.doi.org/10.1186/s12887-020-02136-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236281PMC

The impact of having a baby with cleft lip and palate on parents and on parent-baby relationship: the first French prospective multicentre study.

BMC Pediatr 2020 May 18;20(1):230. Epub 2020 May 18.

HUPNVS Hôpital Bichat - Claude-Bernard, Univ Paris Denis Diderot, CESP Inserm U 1178 et LPPS, 4057, Paris, EA, France.

Background: The objective of this prospective, multidisciplinary and multicenter study was to explore the effect of a cleft lip, associated or not with a cleft palate, on parents, on parent-infant relationship, and on the baby's relational development. It also highlighted how the type of cleft and the timing of the surgery could impact this effect.

Method: 158 infants, with Cleft lip with or without Palate, and their parents participated in this multicenter prospective cohort. Read More

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http://dx.doi.org/10.1186/s12887-020-02118-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236125PMC

Associations between rapid weight gain in infancy and weight status among urban Aboriginal children participating in the Gudaga study: nine-year results from a cohort study.

BMC Pediatr 2020 May 18;20(1):224. Epub 2020 May 18.

Centre for Health Equity Training, Research and Evaluation (CHETRE), part of the Centre for Primary Health Care and Equity, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, 2052, Australia.

Background: Rapid weight gain (RWG) in infants is associated with overweight and obesity in childhood and beyond, highlighting the need for early intervention.

Methods: Data from a birth cohort of Australian Aboriginal and Torres Strait Islander children living in an urban area were analysed to determine the prevalence of RWG in infancy and the association between RWG and overweight and obesity, categorised using both body mass index and waist to height ratio from birth to 9 years.

Results: The prevalence of overweight and obesity is higher in this cohort (at 47%) than the population average. Read More

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http://dx.doi.org/10.1186/s12887-020-02121-wDOI Listing

Effects of journal therapy counseling with anxious pregnant women on their infants' sleep quality: a randomized controlled clinical trial.

BMC Pediatr 2020 May 18;20(1):229. Epub 2020 May 18.

School of Nursing and Midwifery, Tabriz University of Medical Science, Tabriz, Iran.

Background: Sleep is especially important for infants, since it stimulates the development of neural connections in their brains. Psychological stress such as anxiety could affect sleep quality. This study investigated the effects of journal therapy counseling sessions on the infants' sleep quality based on mothers' perception (primary outcome), maternal anxiety, infants' anthropometric and developmental parameters, and the frequency of exclusive breastfeeding (secondary outcomes). Read More

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http://dx.doi.org/10.1186/s12887-020-02132-7DOI Listing

Proximal and distal predictors of self-regulatory change in children aged 4 to 7 years.

BMC Pediatr 2020 May 18;20(1):226. Epub 2020 May 18.

Early Start, School of Education, Faculty of Social Sciences, University of Wollongong, Wollongong, Australia.

Background: Growth in early self-regulation skills has been linked to positive health, wellbeing, and achievement trajectories across the lifespan. While individual studies have documented specific influences on self-regulation competencies in early childhood, few have modelled a comprehensive range of predictors of self-regulation change across health, development, and environment simultaneously. This study aimed to examine the concurrent associations among a range of proximal and distal influences on change in children's self-regulation skills over 2 years from age 4-5 years. Read More

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http://dx.doi.org/10.1186/s12887-020-02133-6DOI Listing

Effect of feeding mode on infant growth and cognitive function: study protocol of the Chilean infant Nutrition randomized controlled Trial (ChiNuT).

BMC Pediatr 2020 May 18;20(1):225. Epub 2020 May 18.

Institute of Nutrition and Food Technology (INTA), University of Chile, Av El Libano 5524, Macul, Santiago, Chile.

Background: A central aim for pediatric nutrition is to develop infant formula compositionally closer to human milk. Milk fat globule membranes (MFGM) have shown to have functional components that are found in human milk, suggesting that addition of bovine sources of MFGM (bMFGM) to infant formula may promote beneficial outcomes potentially helping to narrow the gap between infants who receive human breast milk or infant formula. The objective of the current study is to determine how the addition of bMFGM in infant formula and consumption in early infancy affects physical growth and brain development when compared to infants fed with a standard formula and a reference group of infants fed with mother's own milk. Read More

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http://dx.doi.org/10.1186/s12887-020-02087-9DOI Listing

Anthropometric measurements of school-going-girls of the Punjab, Pakistan.

BMC Pediatr 2020 May 16;20(1):223. Epub 2020 May 16.

Department of Basic Medical Sciences, College of Medicine, University of Sharjah, Sharjah, UAE.

Background: Child's growth has been considered an important indicator to evaluate health trends in a population and to devise strategies accordingly. The purpose of the present study was to determine most commonly occurring weight abnormalities among school-going girls from Punjab and to compare with international growth references devised by World Health Organization (WHO) and Centre for Disease Control and Prevention (CDC).

Methods: In this cross-sectional study a sample of 10,050 child and adolescent girls from 12 districts, 35 public/private sector schools, located in rural, semi-urban and urban areas of northern, central and southern Punjab were included. Read More

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http://dx.doi.org/10.1186/s12887-020-02135-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229613PMC

Pediatric reporting of genomic results study (PROGRESS): a mixed-methods, longitudinal, observational cohort study protocol to explore disclosure of actionable adult- and pediatric-onset genomic variants to minors and their parents.

BMC Pediatr 2020 May 15;20(1):222. Epub 2020 May 15.

Genomic Medicine Institute, Geisinger, Danville, PA, USA.

Background: Exome and genome sequencing are routinely used in clinical care and research. These technologies allow for the detection of pathogenic/likely pathogenic variants in clinically actionable genes. However, fueled in part by a lack of empirical evidence, controversy surrounds the provision of genetic results for adult-onset conditions to minors and their parents. Read More

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http://dx.doi.org/10.1186/s12887-020-02070-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227212PMC

The mediating effect of dietary patterns on the association between mother's education level and the physical aggression of five-year-old children: a population-based cohort study.

BMC Pediatr 2020 May 15;20(1):221. Epub 2020 May 15.

Institute of Health Policy and Management, School of Public Health, National Taiwan University, 17 Xuzhou Road, Taipei, 100, Taiwan.

Background: Relatively few studies have investigated the effects of diet on behavior problems among preschoolers, particularly, physical aggression. In addition, children raised by poorly educated mothers usually have a higher probability of developing negative outcomes. Additionally, highly educated mothers have a higher probability of providing more healthy foods for their children. Read More

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http://dx.doi.org/10.1186/s12887-020-02126-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227108PMC

Improving transitions in care for children with complex and medically fragile needs: a mixed methods study.

BMC Pediatr 2020 May 14;20(1):219. Epub 2020 May 14.

School of Nursing, Dalhousie University, Halifax, Canada.

Background: Children with medical complexity are a small yet resource intensive population in the Canadian health care system. The process for discharging these children from hospital to home is not yet optimal. The overall goal of this project was to develop recommendations to be included in a provincial strategy to support transitions in care for children with complex and medically fragile needs. Read More

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http://dx.doi.org/10.1186/s12887-020-02117-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222504PMC

A rare case of pediatric recurrent rhabdomyolysis with compound heterogenous variants in the LPIN1.

BMC Pediatr 2020 May 14;20(1):218. Epub 2020 May 14.

Department of Nephrology, Children's Hospital of Nanjing Medical University, 72 Guangzhou Road, Nanjing, 210029, Jiangsu Province, China.

Background: Lipin-1, encoded by LPIN1 gene, serves as an enzyme and a transcriptional co-regulator to regulate lipid metabolism and mitochondrial respiratory chain. Autosomal recessive mutations in LPIN1 were recognized as one of the most common causes of pediatric recurrent rhabdomyolysis in western countries. However, to date, there were only a few cases reported in Asian group. Read More

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http://dx.doi.org/10.1186/s12887-020-02134-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222443PMC

An epidemiological investigation of food allergy among children aged 3 to 6 in an urban area of Wenzhou, China.

BMC Pediatr 2020 May 14;20(1):220. Epub 2020 May 14.

Department of Pediatric Pulmonology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 109 Xueyuan Road, Wenzhou, 325027, Zhejiang Province, China.

Background: The prevalence of food allergy (FA) has increased worldwide. In China, the prevalence of FA in infants and school-aged children is well known, but the prevalence in preschool children is unknown.

Methods: A total of 4151 preschool children aged 3 to 6 years in urban Wenzhou, China, were recruited for this cross-sectional study. Read More

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http://dx.doi.org/10.1186/s12887-020-02115-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227185PMC

Women's knowledge towards neonatal danger signs and its associated factors in Ethiopia: a systematic review and meta-analysis.

BMC Pediatr 2020 May 14;20(1):217. Epub 2020 May 14.

Department of Medical Laboratory Sciences, College of Health Sciences, Woldia University, P.O.Box:400, Woldia, Ethiopia.

Introduction: Reducing neonatal mortality is an essential part of the third Sustainable Development Goal, to end preventable child deaths. Neonatal danger signs are the most common cause of neonatal mortality and morbidity. In Ethiopia, most babies are born at home or are discharged from the health institutions in the first 24 h, as a result enhancing women's knowledge towards neonatal danger signs and its complication might reduce neonatal morbidity and mortality. Read More

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http://dx.doi.org/10.1186/s12887-020-02098-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222534PMC

Postpartum vitamin A supplementation for HIV-positive women is not associated with mortality and morbidity of their breastfed infants: evidence from multiple national surveys in sub-Saharan Africa.

BMC Pediatr 2020 May 13;20(1):214. Epub 2020 May 13.

School of Public Health, Addis Ababa University, Addis Ababa, Ethiopia.

Background: Vitamin A supplementation (VAS) in the postpartum period improves the vitamin A concentration of breast milk and vitamin A status is an important predictor of childhood survival. It is also known that Vitamin A Deficiency (VAD) is more prevalent in HIV-infected women. This study investigated the association between vitamin A supplements provided to HIV-positive women in the postpartum period and mortality and morbidity of their breastfed infants in sub-Saharan Africa (SSA) where the prevalence of VAD and HIV is high. Read More

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http://dx.doi.org/10.1186/s12887-020-02131-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218630PMC
May 2020
1.918 Impact Factor

Effectiveness of clinical training on improving essential newborn care practices in Bossaso, Somalia: a pre and postintervention study.

BMC Pediatr 2020 May 13;20(1):215. Epub 2020 May 13.

Save the Children International, Mogadishu, Somalia.

Background: Increasingly, neonatal mortality is concentrated in settings of conflict and political instability. To promote evidence-based practices, an interagency collaboration developed the Newborn Health in Humanitarian Settings: Field Guide. The essential newborn care component of the Field Guide was operationalized with the use of an intervention package encompassing the training of health workers, newborn kit provisions and the installation of a newborn register. Read More

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http://dx.doi.org/10.1186/s12887-020-02120-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222459PMC

Social developmental delays among 3 to 6 year old children in preschools in German social hotspots: results of a dynamic prospective cohort study.

BMC Pediatr 2020 May 13;20(1):216. Epub 2020 May 13.

Institute for Community Medicine, Department Epidemiology of Health Care and Community Health, University Medicine Greifswald, Ellernholzstraße 1-2, 17487, Greifswald, Germany.

Background: Social skills are valid predictors for school readiness and subsequent school success. The federal state law for child day-care and preschools in Mecklenburg-Western Pomerania, a federal state in Germany, provides additional funds for the targeted and individualized promotion of social developmental delays for children in preschools in social hotspots. The law grants additional funds to eligible preschools, provided that each child's development is documented with a standardized, objective and valid screening instrument. Read More

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http://dx.doi.org/10.1186/s12887-020-02128-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222296PMC

Risk factors of malnutrition in Chinese children with congenital heart defect.

BMC Pediatr 2020 May 13;20(1):213. Epub 2020 May 13.

Cardiac Intensive Care Unit, Department of Thoracic and Cardiovascular Surgery, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, 1678 Dongfang Road, Shanghai, 200127, China.

Background: The study aimed to investigate the risk factors of malnutrition in children with congenital heart defect (CHD) in China.

Methods: This cohort study was performed at the biggest pediatric heart center in China; 3252 patients with CHD who underwent cardiac surgeries in 2013 were included. Anthropometric measurements included weight for age Z score (WAZ), weight for height Z score (WHZ), and height for age Z score (HAZ). Read More

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http://dx.doi.org/10.1186/s12887-020-02124-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218652PMC

A case report of one vasovagal syncope patient with third-degree atrioventricular block caused by SCN5A gene mutation and literature review.

BMC Pediatr 2020 May 12;20(1):211. Epub 2020 May 12.

Department of Cardiology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.

Background: Vasovagal syncope (VVS) is common in children and significantly affects their quality of life. To our knowledge, this the first case report of SCN5A gene mutation associated with VVS and third-degree atrioventricular block (atrioventricular block, AVB), which could help pediatricians aware that VVS is not always a benign condition and help to identify VVS children at the risk of sudden death.

Case Presentation: A twelve-year-old male child was admitted to Beijing Children's Hospital of Capital Medical University for chest tightness for 9 days and syncope in July 2018. Read More

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http://dx.doi.org/10.1186/s12887-020-02123-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216648PMC

Factors associated with early childhood stunted growth in a 2012-2015 birth cohort monitored in the rural Msambweni area of coastal Kenya: a cross-sectional study.

BMC Pediatr 2020 May 12;20(1):208. Epub 2020 May 12.

Stanford University School of Medicine, 291 Campus Drive, Stanford, CA, 94305, USA.

Background: Chronic malnutrition, often measured as stunted growth, is an understudied global health problem. Though poor nutritional intake has been linked to stunted growth, there is evidence suggesting environmental exposures may have a significant role in its occurrence. Here, we characterize the non-nutritional prenatal and postnatal factors that contribute to early childhood stunted growth in rural coastal Kenya. Read More

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http://dx.doi.org/10.1186/s12887-020-02110-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216696PMC

A phase II JN-I-10 efficacy study of IDRF-based surgical decisions and stepwise treatment intensification for patients with intermediate-risk neuroblastoma: a study protocol.

BMC Pediatr 2020 May 12;20(1):212. Epub 2020 May 12.

Department of Pediatric Surgery, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan.

Background: Few clinical trials have been reported for patients with intermediate-risk neuroblastoma because of the scarcity of the disease and the variety of clinical and biological characteristics. A multidisciplinary treatment that consists of multidrug chemotherapy and surgery is expected to lead to a good prognosis with few complications. Therefore, a clinical trial for patients with intermediate-risk tumors was designed to establish a standard treatment that reduces complications and achieves good outcomes. Read More

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http://dx.doi.org/10.1186/s12887-020-02061-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218561PMC

Diagnostic test accuracy of new generation tympanic thermometry in children under different cutoffs: a systematic review and meta-analysis.

BMC Pediatr 2020 May 12;20(1):210. Epub 2020 May 12.

Nursing Department, Hospital Affiliated 5 to Nantong University (Taizhou People's Hospital), 366 Taihu Road, Medical High-tech district, Taizhou, Jiangsu Province, China.

Background: The infrared tympanic thermometer (IRTT) is a popular method for temperature screening in children, but it has been debated for the low accuracy and reproducibility compared with other measurements. This study was aimed to identify and quantify studies reporting the diagnostic accuracy of the new generation IRTT in children and to compare the sensitivity and specificity of IRTT under different cutoffs and give the optimal cutoff.

Methods: Articles were derived from a systematic search in PubMed, Web of Science Core Collection, and Embase, and were assessed for internal validity by the Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). Read More

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http://dx.doi.org/10.1186/s12887-020-02097-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216633PMC