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    2093 results match your criteria BMC Veterinary Research [Journal]

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    Diffusion-weighted imaging of the brains of dogs with idiopathic epilepsy.
    BMC Vet Res 2017 Nov 15;13(1):338. Epub 2017 Nov 15.
    Department of Veterinary Clinical Sciences, Small Animal Clinic, Justus-Liebig-University Giessen, Frankfurter Straße 108, 35392, Giessen, Germany.
    Background: Idiopathic epilepsy is one of the most common neurological disorders in dogs. Unfortunately, up to 30% of dogs with idiopathic epilepsy show no improvement under antiepileptic drug treatment. Diffusion-weighted imaging is used in human medicine to identify epileptogenic foci in the brain to allow for more invasive treatments such as deep brain stimulation or surgical removal. Read More

    Molecules produced by probiotics prevent enteric colibacillosis in pigs.
    BMC Vet Res 2017 Nov 15;13(1):335. Epub 2017 Nov 15.
    Canadian Research Institute for Food Safety, University of Guelph, Guelph, ON, N1G 2W1, Canada.
    Background: With the advent of antimicrobial resistance in animal pathogens, novel methods to combat infectious diseases are being sought. Among these, probiotics have been proposed as a means of promoting animal health but problems with their use has been reported. Research has demonstrated that bioactive molecules produced during the growth of certain probiotics interfere with bacterial cell-to-cell communication, which consequently results in an attenuation of virulence in a number of pathogens, including E. Read More

    Detection of rabbit Haemorrhagic disease virus 2 during the wild rabbit (Oryctolagus cuniculus) eradication from the Berlengas archipelago, Portugal.
    BMC Vet Res 2017 Nov 15;13(1):336. Epub 2017 Nov 15.
    Instituto Nacional de Investigação Agrária e Veterinária (INIAV), Laboratório de Virologia. Av. da República, Quinta do Marquês, 2780-157, Oeiras, Portugal.
    Background: In the regular wildlife monitoring action carried out in the summer of the past few years at the Berlenga Island, wild rabbits (Oryctolagus cuniculus) have been repeatedly found dead. However, the origin of those deaths was never investigated. Our aim was to investigate the cause of death of 11 rabbits collected between April and May 2016. Read More

    Gene expression analyses of the small intestine of pigs in the ex-evacuation zone of the Fukushima Daiichi Nuclear Power Plant.
    BMC Vet Res 2017 Nov 15;13(1):337. Epub 2017 Nov 15.
    Department of Pathology, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Miyagi, Japan.
    Background: After the accident at the Fukushima Daiichi Nuclear Power Plant, radioactive contaminants were released over a widespread area. Monitoring the biological effects of radiation exposure in animals in the ex-evacuation zone should be continued to understand the health effects of radiation exposure in humans. The present study aimed to clarify the effects of radiation by investigating whether there is any alteration in the morphology and gene expressions of immune molecules in the intestine of pigs and inobuta (wild boar and domestic pig hybrid) in the ex-evacuation zone in 2012. Read More

    In vitro properties of concentrated canine platelets stored in two additive solutions: a comparative study.
    BMC Vet Res 2017 Nov 15;13(1):334. Epub 2017 Nov 15.
    Department of Veterinary Clinical Pathology, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
    Background: Platelet transfusion therapy poses many challenges in veterinary clinical practice. Lack of readily available blood donors, short shelf-life, and inability to administer a sufficient number of platelets to meet a dog's transfusion need are the major difficulties encountered. Platelet additive solutions are already in use at American and European human blood banks, showing to be a realistic alternative. Read More

    MicroRNA profiling of dogs with transitional cell carcinoma of the bladder using blood and urine samples.
    BMC Vet Res 2017 Nov 15;13(1):339. Epub 2017 Nov 15.
    Department of Urology, University of California, Davis, School of Medicine, Sacramento, CA, USA.
    Background: Early signs of canine transitional cell carcinoma (TCC) are frequently assumed to be caused by other lower urinary tract diseases (LUTD) such as urinary tract infections, resulting in late diagnosis of TCC which could be fatal. The development of a non-invasive clinical test for TCC could dramatically reduce mortality. To determine whether microRNAs (miRNAs) can be used as non-invasive diagnostic biomarkers, we assessed miRNA expression in blood and/or urine from dogs with clinically normal bladders (n = 28), LUTD (n = 25), and TCC (n = 17). Read More

    Survey of vector-borne agents in feral cats and first report of Babesia gibsoni in cats on St Kitts, West Indies.
    BMC Vet Res 2017 Nov 13;13(1):331. Epub 2017 Nov 13.
    College of Veterinary Medicine, Auburn University, Auburn, AL, USA.
    Background: As there is little data on vector-borne diseases of cats in the Caribbean region and even around the world, we tested feral cats from St Kitts by PCR to detect infections with Babesia, Ehrlichia and spotted fever group Rickettsia (SFGR) and surveyed them for antibodies to Rickettsia rickettsii and Ehrlichia canis.

    Results: Whole blood was collected from apparently healthy feral cats during spay/ neuter campaigns on St Kitts in 2011 (N = 68) and 2014 (N = 52). Sera from the 52 cats from 2014 were used to detect antibodies to Ehrlichia canis and Rickettsia rickettsii using indirect fluorescent antibody tests and DNA extracted from whole blood of a total of 119 cats (68 from 2011, and 51 from 2014) was used for PCRs for Babesia, Ehrlichia and Rickettsia. Read More

    Frequency of canine nt230(del4) MDR1 mutation in prone pure breeds, their crosses and mongrels in Israel - insights from a worldwide comparative perspective.
    BMC Vet Res 2017 Nov 13;13(1):333. Epub 2017 Nov 13.
    Tel Hai College, 12210, Tel-Hai, Israel.
    Background: Sensitivity to macrocyclic lactones, which are commonly used in veterinary clinics, was first found in Rough Collies, and was attributed in 2001 to a 4 bp deletion in the MDR1 gene. The list of affected breeds currently includes 13 breeds. Researchers from different countries and continents examined the allelic frequencies of the nt230(del4) MDR1 mutation, emphasizing the clinical importance of this test not only to mutation-prone dogs, but also to their crosses and mongrels, since treatment of a deletion carrier with these compounds may lead to its death. Read More

    Avian infectious bronchitis virus disrupts the melanoma differentiation associated gene 5 (MDA5) signaling pathway by cleavage of the adaptor protein MAVS.
    BMC Vet Res 2017 Nov 13;13(1):332. Epub 2017 Nov 13.
    Jiangsu Co-Innovation Center for Prevention of Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, 225009, China.
    Background: Melanoma differentiation associated gene 5 (MDA5) and retinoic acid-inducible gene-I (RIG-I) selectively sense cytoplasmic viral RNA to induce an antiviral immune response. Infectious bronchitis virus (IBV) is one of the most important infectious agents in chickens, and in chicken cells, it can be recognized by MDA5 to activate interferon production. RIG-I is considered to be absent in chickens. Read More

    Salivary pH, calcium, phosphorus and selected enzymes in healthy dogs: a pilot study.
    BMC Vet Res 2017 Nov 10;13(1):330. Epub 2017 Nov 10.
    Department of Animal Medicine, Production and Health, University of Padua, Legnaro (Padua), Italy.
    Background: Saliva in dogs, as in humans, is a complex fluid secreted by different salivary glands in the oral cavity to protect the oral mucosa and teeth. The use of saliva as a substitute for blood in diagnosing and prognosticating disease in humans is widely accepted. Salivary biochemistry has also been used as a marker for periodontal disease in humans. Read More

    Leaves from banana (Musa nana) and maize (Zea mays) have no phyto-prophylactic effects on the susceptibility of grass carp (Ctenopharyngodon idella) to Aeromonas hydrophila infection.
    BMC Vet Res 2017 Nov 10;13(1):329. Epub 2017 Nov 10.
    Clinical Division of Fish Medicine, University of Veterinary Medicine, Vienna, Austria.
    Background: The ubiquitous and opportunistic bacterial pathogen Aeromonas hydrophila has been associated with ulcerative dermatitis in fish, especially under stressful conditions. It can cause severe losses in fresh water aquaculture and is particularly prevalent in tropical and subtropical regions. Fresh leaves from maize and bananas have been used as feed supplement by fish farmers in Vietnam and it has been reported that they may have phyto-prophylactic benefits. Read More

    The nutritional status affects the complete blood count of goats experimentally infected with Haemonchus contortus.
    BMC Vet Res 2017 Nov 9;13(1):326. Epub 2017 Nov 9.
    URZ, INRA, 97170, Petit-Bourg, Guadeloupe, France.
    Background: Gastrointestinal nematode (GIN) remains the most important pathogenic constraint of small ruminant production worldwide. The improvement of the host immune response against GIN though breeding for improved animal resistance, vaccination and nutritional supplementation appear as very promising methods. The objective of this study was to investigate the effect of four nutritional status differing in protein and energy levels (Hay: 5. Read More

    Case definition terminology for paratuberculosis (Johne's disease).
    BMC Vet Res 2017 Nov 9;13(1):328. Epub 2017 Nov 9.
    Sydney School of Veterinary Science and School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, 425 Werombi Road, Camden, NSW, 2570, Australia.
    Paratuberculosis (Johne's disease) is an economically significant condition caused by Mycobacterium avium subsp. paratuberculosis. However, difficulties in diagnosis and classification of individual animals with the condition have hampered research and impeded efforts to halt its progressive spread in the global livestock industry. Read More

    Molecular characterization of a novel Muscovy duck parvovirus isolate: evidence of recombination between classical MDPV and goose parvovirus strains.
    BMC Vet Res 2017 Nov 9;13(1):327. Epub 2017 Nov 9.
    College of Veterinary Medicine, Yangzhou University, 48 Wenhui East Road, 225009, Yangzhou, Jiangsu Province, People's Republic of China.
    Background: Muscovy duck parvovirus (MDPV) and Goose parvovirus (GPV) are important etiological agents for Muscovy duck parvoviral disease and Derzsy's disease, respectively; both of which can cause substantial economic losses in waterfowl industry. In contrast to GPV, the complete genomic sequence data of MDPV isolates are still limited and their phylogenetic relationships largely remain unknown. In this study, the entire genome of a pathogenic MDPV strain ZW, which was isolated from a deceased Muscovy duckling in 2006 in China, was cloned, sequenced, and compared with that of other classical MDPV and GPV strains. Read More

    Quantitative and qualitative aspects of standing-up behavior and the prevalence of osteochondrosis in Warmblood foals on different farms: could there be a link?
    BMC Vet Res 2017 Nov 9;13(1):324. Epub 2017 Nov 9.
    Department of Equine Sciences, Utrecht University, Utrecht, The Netherlands.
    Background: Osteochondrosis (OC) is a common, clinically important joint disorder in which endochondral ossification is focally disturbed. Reduced blood supply to growing cartilage is considered an important cause of the condition, which has both genetic and environmental origins. Housing conditions can influence cartilage injury through peak-pressure changes during limb sliding. Read More

    Assisting differential clinical diagnosis of cattle diseases using smartphone-based technology in low resource settings: a pilot study.
    BMC Vet Res 2017 Nov 9;13(1):323. Epub 2017 Nov 9.
    Department of Health Management, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, PEI, Canada.
    Background: The recent rise in mobile phone use and increased signal coverage has created opportunities for growth of the mobile Health sector in many low resource settings. This pilot study explores the use of a smartphone-based application, VetAfrica-Ethiopia, in assisting diagnosis of cattle diseases. We used a modified Delphi protocol to select important diseases and Bayesian algorithms to estimate the related disease probabilities based on various clinical signs being present in Ethiopian cattle. Read More

    Clinical monitoring of cardiac output assessed by transoesophageal echocardiography in anaesthetised dogs: a comparison with the thermodilution technique.
    BMC Vet Res 2017 Nov 9;13(1):325. Epub 2017 Nov 9.
    Departamento de Clínica Médica, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, Brazil.
    Background: Cardiac output (CO) is an important haemodynamic parameter to monitor in patients during surgery. However, the majority of the techniques for measuring CO have a limited application in veterinary practice due to their invasive approach and associated complexity and risks. Transoesophageal echocardiography (TEE) is a technique used to monitor cardiac function in human patients during surgical procedures and allows CO to be measured non-invasively. Read More

    Evaluation of an open source method for calculating physical activity in dogs from harness and collar based sensors.
    BMC Vet Res 2017 Nov 7;13(1):322. Epub 2017 Nov 7.
    Institute of Neuroscience, Henry Wellcome Building, The Medical School, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.
    Background: The ability to make objective measurements of physical activity in dogs has both clinical and research applications. Accelerometers offer a non-intrusive and convenient solution. Of the commercialy available sensors, measurements are commonly given in manufacturer bespoke units and calculated with closed source approaches. Read More

    High intensity, short duration pulling in heavy horses: physiological effects of competition and rapid weight change.
    BMC Vet Res 2017 Nov 7;13(1):317. Epub 2017 Nov 7.
    Department of Veterinary Clinical and Diagnostic Sciences, Faculty of Veterinary Medicine, University of Calgary, Calgary, AB, T2N 4N1, Canada.
    Background: The Heavy Horse Pull is a competition where teams of two horses pull an increasingly heavy sled for a short distance. Similar to human wrestlers, some horses may undergo rapid weight change in order to enter a lower weight category. The objectives were to study the physiological effects of this practice as well as of the pulling competition in draft horses. Read More

    Effect of gastric acid-suppressive therapy and biological variation of serum gastrin concentrations in dogs with chronic enteropathies.
    BMC Vet Res 2017 Nov 7;13(1):321. Epub 2017 Nov 7.
    Gastrointestinal Laboratory, Texas A&M University, TAMU 4474, College Station, TX, 77843-4474, USA.
    Background: Serum gastrin concentration can help diagnose gastrinomas in dogs if >3-10× the upper reference limit (URL), but antisecretory therapy and other conditions can also cause hypergastrinemia. Effects of antisecretory therapy (famotidine or ranitidine, omeprazole) on serum gastrin concentration in dogs with chronic enteropathy (CE) and its biological variation (BV) are unknown. Aim of the study was to evaluate serum gastrin in acid-suppressant-treated or -naïve CE dogs; test the association between serum gastrin and histopathologic findings in acid-suppressant-naïve CE dogs; and evaluate the BV of serum gastrin in dogs not receiving any gastric acid suppressive therapy. Read More

    Serological evidence of equine arteritis virus infection and phylogenetic analysis of viral isolates in semen of stallions from Serbia.
    BMC Vet Res 2017 Nov 7;13(1):316. Epub 2017 Nov 7.
    ANSES, Laboratory for Equine Diseases, Virology Unit, Dozulé, France.
    Background: Equine arteritis virus (EAV) is responsible for infections in equids. It can spread easily within the horse population and has a major impact on the horse breeding industry. No EAV outbreak has ever been reported in Serbia. Read More

    Local anaesthetics or their combination with morphine and/or magnesium sulphate are toxic for equine chondrocytes and synoviocytes in vitro.
    BMC Vet Res 2017 Nov 7;13(1):318. Epub 2017 Nov 7.
    Institute of Aging and Chronic Disease, University of Liverpool, Liverpool, UK.
    Background: Chondrotoxic effects of local anaesthetics are well reported in humans and some animal species but knowledge on their toxic effects on synoviocytes or equine chondrocytes or the effects on cellular production of inflammatory cytokines is limited. The purpose of this study was to evaluate the in vitro effects of local anaesthetics, morphine, magnesium sulphate (MgSO4) or their combinations on cell viability and pro-inflammatory cytokine gene expression of equine synoviocytes and chondrocytes. Equine synoviocytes and cartilage explants harvested from normal joints in a co-culture system were exposed to mepivacaine (4. Read More

    No evidence of enteric viral involvement in the new neonatal porcine diarrhoea syndrome in Danish pigs.
    BMC Vet Res 2017 Nov 7;13(1):315. Epub 2017 Nov 7.
    National Veterinary Institute, Technical University of Denmark, Kemitorvet, Lyngby, DK-2800, Denmark.
    Background: The aim of this study was to investigate whether the syndrome New Neonatal Porcine Diarrhoea Syndrome (NNPDS) is associated with a viral aetiology. Four well-managed herds experiencing neonatal diarrhoea and suspected to be affected by NNPDS were included in a case-control set up. A total of 989 piglets were clinically examined on a daily basis. Read More

    Letter to the editor - round table unites to tackle culture change in an effort to improve animal research reporting.
    BMC Vet Res 2017 Nov 7;13(1):314. Epub 2017 Nov 7.
    Norecopa, c/o Norwegian Veterinary Institute, P.O. Box 750 Sentrum, 0106, Oslo, Norway.
    A round table discussion was held during the LAVA-ESLAV-ECLAM conference on Reproducibility of Animal Studies on the 25th of September 2017 in Edinburgh. The aim of the round table was to discuss how to enhance the rate at which the quality of reporting animal research can be improved. This signed statement acknowledges the efforts that participant organizations have made towards improving the reporting of animal studies and confirms an ongoing commitment to drive further improvements, calling upon both academics and laboratory animal veterinarians to help make this cultural change. Read More

    The prevalence of ocular diseases in polish Arabian horses.
    BMC Vet Res 2017 Nov 7;13(1):319. Epub 2017 Nov 7.
    Laboratory of Veterinary Epidemiology and Economics, Faculty of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, Warsaw, Nowoursynowska 159c, 02-786, Warsaw, Poland.
    Background: Equine ocular diseases pose a medical challenge due to long-lasting and cost-consuming therapies as well as economic issues associated with potential decrease in value of affected horses. The scale of the problem is significant but difficult to precisely define because epidemiological data is limited and lacks consistency in presentation. To date, no retrospective studies specifically investigating Arabian horses have been published. Read More

    Evaluation of intravenous regional anaesthesia and four-point nerve block efficacy in the distal hind limb of dairy cows.
    BMC Vet Res 2017 Nov 7;13(1):320. Epub 2017 Nov 7.
    Clinic for Cattle, University of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
    Background: Intravenous regional anaesthesia (IVRA) and hindfoot four-point nerve block anaesthesia (NBA) are recommended for local anaesthesia (LA) in the distal limb of dairy cows. Two studies were conducted to compare the efficacy, time until onset and stress responses to IVRA and NBA in dairy cows. In the first cross-over designed study, eight healthy unsedated German Holstein cows, restrained in lateral recumbency (LR) on a surgical tipping table, were treated with IVRA and NBA using procaine 2% as a local anaesthetic. Read More

    Temporal and spatial distribution of lumpy skin disease outbreaks in Ethiopia in the period 2000 to 2015.
    BMC Vet Res 2017 Nov 6;13(1):310. Epub 2017 Nov 6.
    Quantitative Veterinary Epidemiology, Wageningen University & Research, Droevendaalsesteeg 1, 6708 PB, Wageningen, The Netherlands.
    Background: Lumpy skin disease (LSD) is an infectious viral disease of cattle caused by a virus of the genus Capripoxvirus. LSD was reported for the first time in Ethiopia in 1981 and subsequently became endemic. This time series study was undertaken with the aims of identifying the spatial and temporal distribution of LSD outbreaks and to forecast the future pattern of LSD outbreaks in Ethiopia. Read More

    Ultrasonographically determined renal values and comparisons to serum biochemistry renal variables in aged semi-captive cheetahs (Acinonyx jubatus).
    BMC Vet Res 2017 Nov 6;13(1):312. Epub 2017 Nov 6.
    Department of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, 0110, South Africa.
    Background: Cheetahs in captivity have a high prevalence of chronic renal diseases. We ultrasonographically evaluated the renal volumes, a variety of renal dimensions, interarcuate artery resistive indices (RI) as well as aortic diameters and the length of the ventral aspect of the 6th lumbar vertebrae in 27 aged semi-captive anesthetized cheetahs. Renal size, dimensions and ratios were compared to urine specific gravity, serum creatinine and urea values. Read More

    Characterization of endocannabinoids and related acylethanolamides in the synovial fluid of dogs with osteoarthritis: a pilot study.
    BMC Vet Res 2017 Nov 6;13(1):309. Epub 2017 Nov 6.
    Department of Veterinary Medicine, University of Bari "Aldo Moro", SP. Casamassima km 3, 70010, Bari, Valenzano, Italy.
    Background: Cannabis-based drugs have been shown to be effective in inflammatory diseases. A number of endocannabinoids including N- arachidonoylethanolamide (anandamide, AEA) and 2-arachidonyl glycerol (2-AG) with activity at the cannabinoid receptors (CBR) CBR1 and CBR2, have been identified. Other structurally related endogenous fatty acid compounds such as oleoylethanolamide (OEA) and palmitoyl ethanolamide (PEA) have been identified in biological tissues. Read More

    Development of real-time recombinase polymerase amplification assay for rapid and sensitive detection of canine parvovirus 2.
    BMC Vet Res 2017 Nov 6;13(1):311. Epub 2017 Nov 6.
    College of Life Sciences, Hebei Normal University, No.20, Road E. 2nd Ring South, Yuhua District, Shijiazhuang, Hebei Province, 050024, People's Republic of China.
    Background: Canine parvovirus 2, a linear single-stranded DNA virus belonging to the genus Parvovirus within the family Parvoviridae, is a highly contagious pathogen of domestic dogs and several wild canidae species. Early detection of canine parvovirus (CPV-2) is crucial to initiating appropriate outbreak control strategies. Recombinase polymerase amplification (RPA), a novel isothermal gene amplification technique, has been developed for the molecular detection of diverse pathogens. Read More

    Characterization of respiratory dendritic cells from equine lung tissues.
    BMC Vet Res 2017 Nov 6;13(1):313. Epub 2017 Nov 6.
    Department of Pathobiology & Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, 784 Wilson Rd, A13, East Lansing, MI, 48824, USA.
    Background: Dendritic cells (DCs) are professional antigen-presenting cells that have multiple subpopulations with different phenotypes and immune functions. Previous research demonstrated that DCs have strong potential for anti-viral defense in the host. However, viruses including alphaherpesvirinae have developed strategies to interfere with the function or maturation of DCs, causing immune dysfunction and avoidance of pathogen elimination. Read More

    Effects of selected Palestinian plants on the in vitro exsheathment of the third stage larvae of gastrointestinal nematodes.
    BMC Vet Res 2017 Nov 3;13(1):308. Epub 2017 Nov 3.
    The Institute of Applied Research, The Galilee Society, P.O.B. 437, 20200, Shefa-Amr, Israel.
    Background: Gastrointestinal parasites are one of the main restrictions to small ruminant production. Their pathological importance is primarily related to the major production losses, in quantity or quality, induced by the direct action of worms. Control of these parasites is based exclusively on the frequent use of anthelmintic drugs. Read More

    Extra-uterine (abdominal) full term foetus in a 15-day pregnant rabbit.
    BMC Vet Res 2017 Nov 3;13(1):307. Epub 2017 Nov 3.
    Instituto de Ciencia y Tecnología Animal, Universitad Politècnica de València, 46022, Valencia, Spain.
    Background: While ectopic pregnancies account for 1-2% of all pregnancies, abdominal pregnancy is extremely rare, accounting for approximately 1% of ectopic pregnancies. Extrauterine abdominal pregnancy is defined as the implantation and development of an embryo in the peritoneal cavity. The present report is the first of an incidental case of abdominal pregnancy within four full-term foetus simultaneously with 2 weeks of physiological gestation in a healthy doe rabbit. Read More

    A biomechanical comparison of Kirschner-wire fixation on fracture stability in Salter-Harris type I fractures of the proximal humeral physis in a porcine cadaveric model.
    BMC Vet Res 2017 Oct 25;13(1):306. Epub 2017 Oct 25.
    Surgical and Orthopaedic Research Laboratories (SORL), Prince of Wales Hospital, University of New South Wales, Sydney, Australia.
    Background: The physis is the weakest component of immature long bones, and physeal fractures constitute about 30% of fractures in growing dogs. Fractures of the proximal humeral physis typically have a Salter Harris type I or II configuration. These fractures require accurate reduction and adequate stabilization to allow for any potential continued longitudinal bone growth, in conjunction with physeal fracture healing. Read More

    A summary index for antimicrobial resistance in food animals in the Netherlands.
    BMC Vet Res 2017 Oct 24;13(1):305. Epub 2017 Oct 24.
    National Institute for Public Health and the Environment, PO Box 1, 3720 BA, Bilthoven, the Netherlands.
    Background: The Dutch government has set targets for reduction of antimicrobial usage in food animals, stipulating a 50% reduction in usage (on a weight basis) in 2013 as compared to 2009 and a 70% decrease in 2015. A monitoring program has been instituted to evaluate the impact on antimicrobial resistance (AMR). The Dutch Ministry of Public Health Welfare and Sports has expressed the need for a summary index to present the results of the monitoring data concisely to policy makers. Read More

    Performance of Leishmania PFR1 recombinant antigen in serological diagnosis of asymptomatic canine leishmaniosis by ELISA.
    BMC Vet Res 2017 Oct 23;13(1):304. Epub 2017 Oct 23.
    Instituto de Parasitología y Biomedicina "López Neyra" Consejo Superior de Investigaciones Científicas, Granada, Spain.
    Background: Leishmania infantum is a protozoan parasite transmitted by phlebotomine sand flies that causes life-threatening disease in humans and dogs. The dog is the primary reservoir of the parasite and early diagnosis of canine leishmaniosis is crucial at the clinical and epidemiological level. The currently available serological tests for CanL diagnostic show limitations therefore the aim of the present study was to investigate the diagnostic performance of an indirect antibody ELISA based on the Leishmania infantum recombinant antigen PFR1 in asymptomatically infected dogs. Read More

    Important knowledge gaps among pastoralists on causes and treatment of udder health problems in livestock in southern Ethiopia: results of qualitative investigation.
    BMC Vet Res 2017 Oct 23;13(1):303. Epub 2017 Oct 23.
    International Livestock Research Institute, P. O. Box 5689, Addis Ababa, Ethiopia.
    Background: Ethiopia has high prevalences of udder health problems including clinical and subclinical mastitis across production systems in different livestock species. Previous studies on udder health problems have largely focused on identification of mastitis causing microbial pathogens and associated risk factors. However, relatively little is known about the knowledge and beliefs of livestock keepers regarding udder health problems. Read More

    A description of the gross pathology of drowning and other causes of mortality in seabirds.
    BMC Vet Res 2017 Oct 12;13(1):302. Epub 2017 Oct 12.
    Centre for Ecology and Conservation, University of Exeter, Penryn, Cornwall, TR10 9FE, UK.
    Background: Mortality of seabirds due to anthropogenic causes, especially entrapment in fishing gear, is a matter of increasing international concern. This study aimed at characterising the gross pathology of seabirds that drowned in fishing nets and comparing it with that in other common causes of mortality.

    Results: Post-mortem examinations were performed on 103 common guillemots, 32 razorbills, 37 shags and 5 great northern divers found stranded in Cornwall during 1981-2016. Read More

    Toxoplasma gondii and Neospora caninum in farm-reared ostriches (Struthio camelus) in China.
    BMC Vet Res 2017 Oct 11;13(1):301. Epub 2017 Oct 11.
    Laboratory of Veterinary Pathology, College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450002, People's Republic of China.
    Background: The parasites Toxoplasma gondii (T. gondii) and Neospora caninum (N. caninum) are globally distributed; they infect warm-blooded animals, including many avian species. Read More

    Comparative efficacy of the Leucofeligen™ FeLV/RCP and Purevax™ RCP FeLV vaccines against infection with circulating feline Calicivirus.
    BMC Vet Res 2017 Oct 10;13(1):300. Epub 2017 Oct 10.
    Virbac, 13ème rue, LID, 06511, Carros, France.
    Background: Feline calicivirus (FCV) is a common virus, found worldwide, mainly responsible for chronic ulceroproliferative faucitis and periodontitis. This virus has a high mutation rate, leading to the presence of numerous FCV strains in the field. The objectives of this study was to evaluate and compare the efficacy of two vaccines (Leucofeligen™ FeLV/RCP and Purevax™ RCP FeLV), which differ by their nature (live vs. Read More

    Mycobacterium tuberculosis infection in cattle from the Eastern Cape Province of South Africa.
    BMC Vet Res 2017 Oct 10;13(1):299. Epub 2017 Oct 10.
    Tuberculosis Laboratory, Diagnostic Services Programme, ARC-Onderstepoort Veterinary Research, Private Bag X05, Onderstepoort, Pretoria, 0110, South Africa.
    Background: Mycobacterium tuberculosis is the main causative agent of tuberculosis (TB) in human and Mycobacterium bovis commonly causes tuberculosis in animals. Transmission of tuberculosis caused by both pathogens can occur from human to animals and vice versa.

    Results: In the current study, M. Read More

    Curcumin is a promising inhibitor of genotype 2 porcine reproductive and respiratory syndrome virus infection.
    BMC Vet Res 2017 Oct 10;13(1):298. Epub 2017 Oct 10.
    Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, 712100, China.
    Background: Porcine reproductive and respiratory syndrome virus (PRRSV) could lead to pandemic diseases and huge financial losses to the swine industry worldwide. Curcumin, a natural compound, has been reported to serve as an entry inhibitor of hepatitis C virus, chikungunya virus and vesicular stomatitis virus. In this study, we investigated the potential effect of curcumin on early stages of PRRSV infection. Read More

    Topical use of 5% acyclovir cream for the treatment of occult and verrucous equine sarcoids: a double-blinded placebo-controlled study.
    BMC Vet Res 2017 Oct 6;13(1):296. Epub 2017 Oct 6.
    Department of Surgery and Anaesthesiology of Domestic Animals, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820, Merelbeke, Belgium.
    Background: Previous studies mention the use of topical acyclovir for the treatment of equine sarcoids. Success rates vary and since the bovine papillomavirus (BPV) lacks the presence of a kinase necessary to activate acyclovir, there is no proof of its activity against equine sarcoids.

    Results: Twenty-four equine sarcoids were topically treated with acyclovir cream and 25 with a placebo. Read More

    A descriptive pilot study of cytokine production following stimulation of ex-vivo whole blood with commercial therapeutic feline hydrolyzed diets in individual healthy immunotolerant cats.
    BMC Vet Res 2017 Oct 6;13(1):297. Epub 2017 Oct 6.
    Department of Molecular Biosciences, School of Veterinary Medicine, University of California-Davis, Davis, CA, 95616, USA.
    Background: Hydrolyzed diets are used in companion animals for the diagnosis and treatment of adverse food reaction. Similarly, hydrolyzed formulas are used in human infants with severe inflammatory bowel disease or milk allergy, and these must meet the standard of hypoallergenicity through rigorous testing. Unfortunately, no standards are currently applied to hydrolyzed veterinary therapeutic diets, and data for the immunogenicity of feline diets is also not available. Read More

    Sample size and number of outcome measures of veterinary randomised controlled trials of pharmaceutical interventions funded by different sources, a cross-sectional study.
    BMC Vet Res 2017 Oct 4;13(1):295. Epub 2017 Oct 4.
    Centre for Evidence-based Veterinary Medicine, School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington campus, Loughborough, LE12 5RD, UK.
    Background: Randomised controlled trials (RCTs) are a key component of the veterinary evidence base. Sample sizes and defined outcome measures are crucial components of RCTs. To describe the sample size and number of outcome measures of veterinary RCTs either funded by the pharmaceutical industry or not, published in 2011. Read More

    Safety and efficacy of targeted hyperthermia treatment utilizing gold nanorod therapy in spontaneous canine neoplasia.
    BMC Vet Res 2017 Oct 2;13(1):294. Epub 2017 Oct 2.
    College of Veterinary Medicine, The Ohio State University, Columbus OH AND Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA, USA.
    Background: Hyperthermia is an established anti-cancer treatment but is limited by tolerance of adjacent normal tissues. Parenteral administration of gold nanorods (NRs) as a photosensitizer amplifies the effects of hyperthermia treatment while sparing normal tissues. This therapy is well tolerated and has demonstrated anti-tumor effects in mouse models. Read More

    Polysplenia syndrome with duodenal and pancreatic dysplasia in a Holstein calf: a case report.
    BMC Vet Res 2017 Sep 29;13(1):292. Epub 2017 Sep 29.
    Division of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan.
    Background: Laterality disorders of the abdominal organs include situs inversus totalis that mirrors the arrangements of all internal organs and heterotaxy syndrome (situs ambiguus) in which the thoracic or abdominal organs are abnormally arranged. Heterotaxy is often accompanied by multiple congenital malformations, and it generally comprises asplenia and polysplenia syndromes. To our knowledge, polysplenia syndrome has been reported in only three cattle, and computerized tomographic (CT) images of these animals were not obtained. Read More

    In vitro susceptibility of Borrelia burgdorferi isolates to three antibiotics commonly used for treating equine Lyme disease.
    BMC Vet Res 2017 Sep 29;13(1):293. Epub 2017 Sep 29.
    Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, USA.
    Background: Lyme disease in humans is predominantly treated with tetracycline, macrolides or beta lactam antibiotics that have low minimum inhibitory concentrations (MIC) against Borrelia burgdorferi. Horses with Lyme disease may require long-term treatment making frequent intravenous or intramuscular treatment difficult and when administered orally those drugs may have either a high incidence of side effects or have poor bioavailability. The aim of the present study was to determine the in vitro susceptibility of three B. Read More

    Phylogenetic assessment reveals continuous evolution and circulation of pigeon-derived virulent avian avulaviruses 1 in Eastern Europe, Asia, and Africa.
    BMC Vet Res 2017 Sep 26;13(1):291. Epub 2017 Sep 26.
    Exotic and Emerging Avian Viral Diseases Research Unit, Southeast Poultry Research Laboratory, US National Poultry Research Center, Agricultural Research Service, USDA, 934 College Station Road, Athens, GA, 30605, USA.
    Background: The remarkable diversity and mobility of Newcastle disease viruses (NDV) includes virulent viruses of genotype VI. These viruses are often referred to as pigeon paramyxoviruses 1 because they are normally isolated and cause clinical disease in birds from the Columbidae family. Genotype VI viruses occasionally infect, and may also cause clinical disease in poultry. Read More

    Quadruplex PCR assay for identification of Corynebacterium pseudotuberculosis differentiating biovar Ovis and Equi.
    BMC Vet Res 2017 Sep 25;13(1):290. Epub 2017 Sep 25.
    Instituto de Ciências Biológicas, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.
    Background: Corynebacterium pseudotuberculosis is classified into two biovars, nitrate-negative biovar Ovis which is the etiologic agent of caseous lymphadenitis in small ruminants and nitrate-positive biovar Equi, which causes abscesses and ulcerative lymphangitis in equines. The aim of this study was to develop a quadruplex PCR assay that would allow simultaneous detection and biovar-typing of C. pseudotuberculosis. Read More

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