2,633 results match your criteria BMC Veterinary Research [Journal]


An epidemiological investigation of porcine circovirus 3 infection in cattle in Shandong province, China.

BMC Vet Res 2019 Feb 13;15(1):60. Epub 2019 Feb 13.

College of Animal Science and Technology, Guangxi University, Nanning, 530004, China.

Background: Porcine circovirus type 3 (PCV3) is a single-stranded, closed circular DNA virus, which causes porcine dermatitis and nephropathy syndrome (PDNS), multisystemic inflammation, and reproductive failure. The present study aimed to investigate the seroprevalence of PCV3 in cattle (Bos taurus) in Shandong province, China, and examine its genome diversity.

Results: PCR amplification and sequencing showed that 74 of 213 bovine samples (34. Read More

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http://dx.doi.org/10.1186/s12917-019-1793-0DOI Listing
February 2019

A longitudinal prospective cohort study investigating the association of premilking stimulation and teat-end shape on milking characteristics and teat tissue condition in dairy cows.

BMC Vet Res 2019 Feb 12;15(1):58. Epub 2019 Feb 12.

Department of Population Medicine and Diagnostic Sciences, Cornell University, Ithaca, NY, 14853, USA.

Background: Premilking udder preparation is essential for harvesting high-quality milk as gently, completely, and quickly as possible. The associations between characteristics such as teat-end shape and premilking stimulation on milking characteristics and machine milking-induced changes to the teat tissue condition have not been rigorously investigated. The primary objective was to investigate the interactive effects of manual premilking stimulation (i. Read More

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http://dx.doi.org/10.1186/s12917-019-1803-2DOI Listing
February 2019

Identification of modifiable factors associated with owner-reported equine laminitis in Britain using a web-based cohort study approach.

BMC Vet Res 2019 Feb 12;15(1):59. Epub 2019 Feb 12.

Epidemiology Department, Centre for Preventive Medicine, Animal Health Trust, Newmarket, Suffolk, UK.

Background: Equine laminitis is a complex disease that manifests as pain and lameness in the feet, often with debilitating consequences. There is a paucity of data that accounts for the multifactorial nature of laminitis and considers time-varying covariates that may be associated with disease development; particularly those that are modifiable and present potential interventions. A previous case-control study identified a number of novel, modifiable factors associated with laminitis which warranted further investigation and corroboration. Read More

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http://dx.doi.org/10.1186/s12917-019-1798-8DOI Listing
February 2019

Renal shear wave elastography and urinary procollagen type III amino-terminal propeptide (uPIIINP) in feline chronic kidney disease.

BMC Vet Res 2019 Feb 11;15(1):54. Epub 2019 Feb 11.

Department of Veterinary Surgery, Faculty of Veterinary Science, Chulalongkorn University, 39 Henri-Dunant Road, Wangmai, Pathumwan, Bangkok, 10330, Thailand.

Background: Chronic kidney disease (CKD) is one of the most common diseases occurring in cats. It is characterized by renal fibrosis, which is strongly correlated with impairment of renal function. Since renal biopsy is not performed routinely in clinical practice, the non-invasive method of ultrasonographic shear-wave elastography (SWE) was used to determine renal parenchymal stiffness. Read More

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http://dx.doi.org/10.1186/s12917-019-1801-4DOI Listing
February 2019

Dexamethasone-induced impairment of post-injury skeletal muscle regeneration.

BMC Vet Res 2019 Feb 11;15(1):56. Epub 2019 Feb 11.

Department of Pathological Anatomy, Faculty of Veterinary Medicine, University of Warmia and Mazury, Oczapowskiego Street 13, 10-719, Olsztyn, Poland.

Background: Due to the routine use of dexamethasone (DEX) in veterinary and human medicine and its negative impact on the rate of wound healing and skeletal muscle condition, we decided to investigate the effect of DEX on the inflammatory and repair phases of skeletal muscle regeneration. In this study, a porcine skeletal muscle injury model was used. The animals were divided into non-treated and DEX-treated (0. Read More

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http://dx.doi.org/10.1186/s12917-019-1804-1DOI Listing
February 2019

The organophosphate pesticide -OP- malathion inducing thyroidal disruptions and failures in the metamorphosis of the Senegalese sole, Solea senegalensis.

BMC Vet Res 2019 Feb 11;15(1):57. Epub 2019 Feb 11.

Instituto de Ciencias Marinas de Andalucía-ICMAN, CSIC Campus Universitario Río San Pedro, 11510, Puerto Real, Cádiz, Spain.

Background: Organophosphate pesticides-OP-, like malathion, can alter the normal functioning of neuro-endocrine systems (e.g., hypothalamus-pituitary-thyroid-HPT- axis), and to interfere on the thyroidal homeostasis. Read More

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http://dx.doi.org/10.1186/s12917-019-1786-zDOI Listing
February 2019

Histamine H receptor antagonists enhance the efficacy of antibacterials against Escherichia coli.

BMC Vet Res 2019 Feb 11;15(1):55. Epub 2019 Feb 11.

Department of Pharmacology, Toxicology and Pharmacy, University of Veterinary Medicine Hannover Foundation, Hannover, Germany.

Background: H receptor antagonists are commonly used for the treatment of allergic diseases. The aim of this study was to find out, if antihistaminic compounds like mepyramine have the ability to influence the activity of antibacterials. Therefore, the checkerboard method was chosen to detect these possible effects in vitro. Read More

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http://dx.doi.org/10.1186/s12917-019-1797-9DOI Listing
February 2019

Effect of prebiotic supplementation with stabilized rice bran in milk of pre-weaned organic Holstein calves.

BMC Vet Res 2019 Feb 7;15(1):53. Epub 2019 Feb 7.

Department of Animal Sciences, Colorado State University, Fort Collins, CO, 80523, USA.

Background: The first month of life possess significant challenges for dairy calves due to high susceptibility to digestive diseases. The objective of this study was to evaluate the effect of prebiotic supplementation with stabilized rice bran (SRB) in milk on health, immunity, and performance of pre-weaned organic dairy calves. Holstein heifer calves (n = 90) were enrolled at 6 ± 1 days old and monitored for 28 days, from July to August 2017. Read More

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http://dx.doi.org/10.1186/s12917-019-1802-3DOI Listing
February 2019

Highly invasive and poorly differentiated corneal squamous cell carcinoma in a dog.

BMC Vet Res 2019 Feb 7;15(1):52. Epub 2019 Feb 7.

Departamento de Producción y Sanidad Animal, Salud Pública Veterinaria y Ciencia y Tecnología de los alimentos, Unidad de Histología y Anatomía Patológica, Facultad de Veterinaria, Universidad Cardenal Herrera-CEU, CEU Universities, Tirant lo Blanc, 7, 46115, Alfara del Patriarca, Valencia, Spain.

Background: Primary corneal tumors are unusual in dogs although there has been a rise in the prevalence of canine corneal squamous cell carcinoma in the past decades due to different factors. Exposure to ultraviolet radiation, presence of chronic keratitis or history of superficial trauma are some of them. We report for the first time a highly infiltrative corneal neoplasia with both exophytic and deep stromal growth, which presented atypical histologic features of a squamous cell carcinoma. Read More

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http://dx.doi.org/10.1186/s12917-019-1790-3DOI Listing
February 2019

Susceptibility breakpoint for Danofloxacin against swine Escherichia coli.

BMC Vet Res 2019 Feb 4;15(1):51. Epub 2019 Feb 4.

Heilongjiang Key Laboratory for Animal Disease Control and Pharmaceutical Development. Faculty of Basic Veterinary Science, College of Veterinary Medicine, Northeast Agricultural University, 600 Changjiang Road, Xiangfang District, Harbin, People's Republic of China.

Background: Improper use of antimicrobials results in poor treatment and severe bacterial resistance. Breakpoints are routinely used in the clinical laboratory setting to guide clinical decision making. Therefore, the objective of this study was to establish antimicrobial susceptibility breakpoints for danofloxacin against Escherichia coli (E. Read More

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http://dx.doi.org/10.1186/s12917-019-1783-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360659PMC
February 2019

Prion protein polymorphisms associated with reduced CWD susceptibility limit peripheral PrP deposition in orally infected white-tailed deer.

BMC Vet Res 2019 Feb 4;15(1):50. Epub 2019 Feb 4.

Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada.

Background: Chronic wasting disease (CWD) is a prion disease affecting members of the Cervidae family. PrP primary structures play a key role in CWD susceptibility resulting in extended incubation periods and regulating the propagation of CWD strains. We analyzed the distribution of abnormal prion protein (PrP) aggregates in brain and peripheral organs from orally inoculated white-tailed deer expressing four different PRNP genotypes: Q95G96/Q95G96 (wt/wt), S96/wt, H95/wt and H95/S96 to determine if there are substantial differences in the deposition pattern of PrP between different PRNP genotypes. Read More

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http://dx.doi.org/10.1186/s12917-019-1794-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360794PMC
February 2019

Validation of canine prostate volumetric measurements in computed tomography determined by the slice addition technique using the Amira program.

BMC Vet Res 2019 Feb 4;15(1):49. Epub 2019 Feb 4.

Small Animal Clinic, University of Veterinary Medicine Hannover, Foundation, Hannover, Bünteweg 9, D-30559, Hannover, Germany.

Background: Prostatic diseases are common and mostly associated with enlargement of the accessory gland. Thus, determining the prostate size has become a main criterion for evaluating prostate health status. Computed tomography (CT) is recommended as a beneficial tool for evaluating prostate size, morphology and surrounding tissues. Read More

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http://dx.doi.org/10.1186/s12917-019-1778-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360749PMC
February 2019

All-trans retinoic acid inhibits lipopolysaccharide-induced inflammatory responses in bovine adipocytes via TGFβ1/Smad3 signaling pathway.

BMC Vet Res 2019 Feb 1;15(1):48. Epub 2019 Feb 1.

Key Laboratory of Zoonoses Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, Jilin, China.

Background: Dairy cows with metabolic disorder in peripartal period display high inflammatory levels. Adipose tissue is a major endocrine organ, which is closely related to systemic inflammation. Retinoic acid (RA), an active metabolite of vitamin A, has shown potential therapeutic immunomodulatory properties. Read More

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http://dx.doi.org/10.1186/s12917-019-1791-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359792PMC
February 2019
2 Reads

A radical form of nitric oxide inhibits porcine circovirus type 2 replication in vitro.

BMC Vet Res 2019 Feb 1;15(1):47. Epub 2019 Feb 1.

Institute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences,Key Laboratory of Veterinary Diagnosis, Jiangsu Academy of Agricultural Sciences, Key Laboratory of Veterinary Biological Engineering and Technology, Ministry of Agriculture, Nanjing, 210014, China.

Background: Porcine circovirus type 2 (PCV2) is the causal agent of postweaning multisystemic wasting syndrome (PMWS), causing large economical losses of the global swine industry. Nitric oxide (NO), as an important signaling molecule, has antiviral activity on some viruses. To date, there is little information on the role of NO during PCV2 infection. Read More

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http://dx.doi.org/10.1186/s12917-019-1796-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359798PMC
February 2019

Infection and treatment method (ITM) vaccine against East Coast fever: reducing the number of doses per straw for use in smallholder dairy herds by thawing, diluting and refreezing already packaged vaccine.

BMC Vet Res 2019 Jan 31;15(1):46. Epub 2019 Jan 31.

International Livestock Research Institute, P.O.Box 30709-00100, Old Naivasha Road, Nairobi, Kenya.

Background: The Infection and Treatment Method (ITM) of vaccination is the only immunization procedure currently available to protect cattle against East Coast fever (ECF), a tick-transmitted disease responsible for losses of several hundreds of millions of dollars per year in sub-Saharan Africa. The vaccine comprises a homogenized preparation of infected ticks packaged in straws and stored in liquid nitrogen. The current manufacturing protocol results in straws containing 30-40 doses (ILRI 0804), which is impractical for immunizing small herds as found in dairy and smallholder farming systems. Read More

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http://dx.doi.org/10.1186/s12917-019-1787-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357393PMC
January 2019

Stimulation of bovine monocyte-derived macrophages with lipopolysaccharide, interferon-ɣ, Interleukin-4 or Interleukin-13 does not induce detectable changes in nitric oxide or arginase activity.

BMC Vet Res 2019 Jan 31;15(1):45. Epub 2019 Jan 31.

Institute of Infection and Global Health, University of Liverpool, 146 Brownlow Hill, Liverpool, L3 5RF, UK.

Background: Bacterial lipopolysaccharide and interferon-γ stimulation of rodent macrophages in vitro induces up-regulation of inducible nitric oxide synthase, whereas interleukin-4 stimulation results in increased activity of arginase-1. Thus different stimulants result in differing macrophage phenotypes, appropriate for responses to a range of pathogens. The current study was conducted in order to determine whether bovine macrophages derived from monocytes and spleen respond similarly. Read More

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http://dx.doi.org/10.1186/s12917-019-1785-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357487PMC
January 2019
1 Read

Bacterial species associated with interdigital phlegmon outbreaks in Finnish dairy herds.

BMC Vet Res 2019 Jan 29;15(1):44. Epub 2019 Jan 29.

Veterinary Bacteriology and Pathology unit, Finnish Food Authority, Mustialankatu 3, 00790, Helsinki, Finland.

Background: Severe outbreaks of bovine interdigital phlegmon (IP) have occurred recently in several free stall dairy herds in Finland. We studied the aetiology of IP in such herds, and the association of bacterial species with the various stages of IP and herds of various morbidity of IP. Nineteen free stall dairy herds with IP outbreaks and three control herds were visited and bacteriological samples collected from cows suffering from IP (n = 106), other hoof diseases (n = 58), and control cows (n = 64). Read More

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http://dx.doi.org/10.1186/s12917-019-1788-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352363PMC
January 2019
1 Read

Staphylococcus pseudintermedius septicemia in puppies after elective cesarean section: confirmed transmission via dam's milk.

BMC Vet Res 2019 Jan 28;15(1):41. Epub 2019 Jan 28.

Clinic for Reproduction and Large Animals, Veterinary Faculty, University of Ljubljana, Gerbičeva 60, 1000, Ljubljana, Slovenia.

Background: In humans, transmission of bacteria causing fatal sepsis in the neonates through mother's milk has been reported. In dogs, it is believed that bacteria from canine milk are not the primary cause of neonatal infections. Staphylococcus pseudintermedius is colonizing the skin and mucocutaneous junctions in adult dogs and can act as an opportunistic pathogen. Read More

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http://dx.doi.org/10.1186/s12917-019-1795-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348621PMC
January 2019
2 Reads

Two-dimensional echocardiographic measurements of the right coronary artery in healthy horses - a pilot study.

BMC Vet Res 2019 Jan 28;15(1):43. Epub 2019 Jan 28.

Department of Internal Medicine and Clinic of Diseases of Horses, Dogs and Cats, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, C.K. Norwida 25, 50-375, Wroclaw, Poland.

Background: Precise understanding of the dimensions of the vascular lumina is essential for accurate interpretation of cardiac vessels imaging. To the authors' best knowledge, this is the first study focusing on the ultrasound measurement of the right coronary artery (RCA) in the horse. The aim of this study was to determine both the ultrasonographic range of the normal diameter and lumen area of the RCA in horses and the influence of gender, age and level of training on the RCA dimensions. Read More

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http://dx.doi.org/10.1186/s12917-019-1792-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348654PMC
January 2019
1 Read

Exosomes isolation and identification from equine mesenchymal stem cells.

BMC Vet Res 2019 Jan 28;15(1):42. Epub 2019 Jan 28.

Institute of Veterinary-Anatomy, -Histology and -Embryology, Faculty of Veterinary Medicine, Justus-Liebig-University Giessen, Frankfurter Strasse 98, Giessen, 35392, Germany.

Background: Mesenchymal stem cells are used for different therapeutic approaches, e.g. for osteoarthritis, lesions of the tendon as well as for bone defects. Read More

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https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-
Publisher Site
http://dx.doi.org/10.1186/s12917-019-1789-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348641PMC
January 2019
2 Reads

Oral pre-administration of Purslane polysaccharides enhance immune responses to inactivated foot-and-mouth disease vaccine in mice.

BMC Vet Res 2019 Jan 25;15(1):38. Epub 2019 Jan 25.

Department of Pharmaceutical Engineering, College of Life Science & Biotechnology, Heilongjiang August First Land Reclamation University, Daqing High-Tech Industrial Development Zone, Daqing, 163319, People's Republic of China.

Background: Foot-and-mouth disease (FMD) is one of the greatest disease threats to animal husbandry worldwide. Though various vaccines against foot-and-mouth disease virus (FMDV) have been developed, vaccine effectiveness is still not satisfactory. In this work, we studied the potential ability of Purslane polysaccharide (POL-P3b) as a nutrient food additive to enhance immune responses to FMD vaccination in mice. Read More

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http://dx.doi.org/10.1186/s12917-019-1782-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347817PMC
January 2019
3 Reads

Prognostic significance of circulating microRNA-214 and -126 in dogs with appendicular osteosarcoma receiving amputation and chemotherapy.

BMC Vet Res 2019 Jan 25;15(1):39. Epub 2019 Jan 25.

Flint Animal Cancer Center, Department of Clinical Sciences, Colorado State University, Fort Collins, CO, 80523, USA.

Background: Dogs with appendicular osteosarcoma (OSA) receiving standard amputation and adjuvant chemotherapy demonstrate variable outcome with treatment; however, additional biomarkers would be helpful for predicting their outcome. In the present study, we assessed the potential of circulating microRNA-214 (miR-214) and - 126 (miR-126) to predict time to metastasis and death in dogs with OSA treated with amputation and chemotherapy.

Results: Seventy-six dogs that fully met inclusion criteria were included in the analysis. Read More

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http://dx.doi.org/10.1186/s12917-019-1776-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347759PMC
January 2019

Use of flexible sensor to characterize biomechanics of canine skin.

BMC Vet Res 2019 Jan 25;15(1):40. Epub 2019 Jan 25.

Department of Civil, Construction, and Environmental Engineering, Iowa State University, Ames, Iowa, United States.

Background: Suture materials and techniques are frequently evaluated in ex vivo studies by comparing tensile strengths. However, the direct measurement techniques to obtain the tensile forces in canine skin are not available, and, therefore, the conditions suture lines undergo is unknown. A soft elastomeric capacitor is used to monitor deformation in the skin over time by sensing strain. Read More

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http://dx.doi.org/10.1186/s12917-018-1755-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347828PMC
January 2019
1 Read

Antibiotic treatment triggers gut dysbiosis and modulates metabolism in a chicken model of gastro-intestinal infection.

BMC Vet Res 2019 Jan 25;15(1):37. Epub 2019 Jan 25.

Department of Food and Nutritional Sciences, University of Reading, Whiteknights, Reading, RG6 6AP, UK.

Background: Infection of the digestive track by gastro-intestinal pathogens results in the development of symptoms ranging from mild diarrhea to more severe clinical signs such as dysentery, severe dehydration and potentially death. Although, antibiotics are efficient to tackle infections, they also trigger dysbiosis that has been suggested to result in variation in weight gain in animal production systems.

Results: Here is the first study demonstrating the metabolic impact of infection by a gastro-intestinal pathogen (Brachyspira pilosicoli) and its resolution by antibiotic treatment (tiamulin) on the host (chicken) systemic metabolism and gut microbiota composition using high-resolution H nuclear magnetic resonance (NMR) spectroscopy and 16S rDNA next generation sequencing (NGS). Read More

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http://dx.doi.org/10.1186/s12917-018-1761-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347850PMC
January 2019
2 Reads

Salinomycin decreases feline sarcoma and carcinoma cell viability when combined with doxorubicin.

BMC Vet Res 2019 Jan 24;15(1):36. Epub 2019 Jan 24.

Department of Clinical Sciences, Cornell University College of Veterinary Medicine, Ithaca, NY, 14853, USA.

Background: Cancer is a significant health threat in cats. Chemoresistance is prevalent in solid tumors. The ionophore salinomycin has anti-cancer properties and may work synergistically with chemotherapeutics. Read More

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http://dx.doi.org/10.1186/s12917-019-1780-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346515PMC
January 2019
1 Read

Evaluation of a self-retaining distractor for hip joint arthroscopy in toy breed dogs.

BMC Vet Res 2019 Jan 23;15(1):35. Epub 2019 Jan 23.

Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Chungnam National University, Daejeon, 34134, South Korea.

Background: Hip arthroscopy has become a viable option over the last few years for small animal orthopedic diseases, including hip dysplasia, osteoarthritis, and joint evaluation. However, the narrow joint spaces make it difficult to manipulate the instrument, and depth of tissues make it difficult to distract the joint space. In addition, it is very difficult to maintain consistent distraction over time with a manual distraction due to hand fatigue. Read More

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http://dx.doi.org/10.1186/s12917-019-1779-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344994PMC
January 2019
1 Read

The unfolded protein response induced by Tembusu virus infection.

BMC Vet Res 2019 Jan 22;15(1):34. Epub 2019 Jan 22.

Institute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences, Jiangsu Province, 210014, People's Republic of China.

Background: Tembusu virus (TMUV), classified in the genus Flavivirus, causes reduced egg production and neurological problems in poultry. Flavivirus replication depends on the host endoplasmic reticulum (ER) and induces ER stress that leads to activation of the cellular unfolded protein response (UPR), an important signalling pathway that regulates many biological functions involved in viral pathogenesis and innate immunity. However, the mechanism of TMUV-induced UPR activation remains unclear. Read More

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http://dx.doi.org/10.1186/s12917-019-1781-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343269PMC
January 2019
2 Reads

Prevalence of bovine fascioliasis and economic impact associated with liver condemnation in abattoirs in Mongu district of Zambia.

BMC Vet Res 2019 Jan 21;15(1):33. Epub 2019 Jan 21.

Department of Veterinary Services, Mulungushi House, Lusaka, Zambia.

Background: Fascioliasis is a trematode zoonotic snail-borne disease of public health and economic importance. The disease causes liver damage and is hardly recognized by medical personnel hence, is rarely considered as the differential diagnosis. In animals, the disease leads to mortalities, growth retardation, drop in livestock production and condemnation of the infected livers during meat inspection. Read More

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http://dx.doi.org/10.1186/s12917-019-1777-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341647PMC
January 2019
7 Reads

A new immunochromatographic assay for on-site detection of porcine epidemic diarrhea virus based on monoclonal antibodies prepared by using cell surface fluorescence immunosorbent assay.

BMC Vet Res 2019 Jan 18;15(1):32. Epub 2019 Jan 18.

Department of Bioengineering, Guangdong Province Key Laboratory of Molecular Immunology and Antibody Engineering, Jinan University, Guangzhou, 510632, People's Republic of China.

Background: Porcine epidemic diarrhea virus (PEDV) is a highly effective pathogen that can cause death of new-born piglet, resulting in big economical loss in pig farming industry. For rapid detection of PEDV, a new immunochromatographic assay (ICA) based on monoclonal antibodies (mAbs) was developed in this study.

Results: The mAbs were prepared by using PEDV positive hybridoma cells that were selected by using cell surface fluorescence immunosorbent assay (CSFIA). Read More

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http://dx.doi.org/10.1186/s12917-019-1773-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339306PMC
January 2019
2 Reads

Polymerase chain reaction combined with fluorescent lateral flow immunoassay based on magnetic purification for rapid detection of canine parvovirus 2.

BMC Vet Res 2019 Jan 17;15(1):30. Epub 2019 Jan 17.

State Key Laboratory of Bioelectronics, Jiangsu Key Laboratory for Biomaterials and Devices, School of Biological Sciences and Medical Engineering and Collaborative Innovation Center of Suzhou Nano Science and Technology, Southeast University, No. 2, Sipailou, Xuanwu District, Nanjing, Jiangsu Province, 210096, People's Republic of China.

Background: Canine parvovirus 2 (CPV-2) is one of the most common etiological agents that cause severe gastroenteritis in puppies. Early accurate diagnosis is important for infected dogs. In recent years, magnetic separation has become an efficient and useful tool for bioassays. Read More

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http://dx.doi.org/10.1186/s12917-019-1774-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337814PMC
January 2019
3 Reads

N-acetylcysteine addition after vitrification improves oocyte mitochondrial polarization status and the quality of embryos derived from vitrified murine oocytes.

BMC Vet Res 2019 Jan 17;15(1):31. Epub 2019 Jan 17.

Jesús Usón Minimally Invasive Surgery Centre, Carretera N-521, km. 41,8, 10071, Cáceres, Spain.

Background: Vitrification is the safest method to cryopreserve oocytes, however the process alters mitochondrial function resulting from increased reactive oxygen species (ROS) production. Our aim was to alleviate ROS stress in vitrified mice oocytes using N-acetylcysteine (NAC at 1 mM), to improve the oocyte's developmental competence.

Results: Hence, four experimental groups were compared: fresh oocytes (F-C), vitrified oocytes (V-C), NAC addition prior to oocyte vitrification (V-NAC-Pre) and NAC addition after vitrification (V-NAC-Post). Read More

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http://dx.doi.org/10.1186/s12917-018-1743-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337864PMC
January 2019
2 Reads

Efficacy of fluralaner spot-on solution for the treatment of Ctenocephalides felis and Otodectes cynotis mixed infestation in naturally infested cats.

BMC Vet Res 2019 Jan 16;15(1):28. Epub 2019 Jan 16.

Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Via Della Veterinaria 1, 80137, Naples, Italy.

Background: Cats can be infested with several ectoparasite species, especially Ctenocephalides felis and Otodectes cynotis. The aim of this study was to evaluate the efficacy of a single topical application of fluralaner against C. felis and O. Read More

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http://dx.doi.org/10.1186/s12917-019-1775-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335790PMC
January 2019
2 Reads

Intravitreal injection of low-dose gentamicin for the treatment of recurrent or persistent uveitis in horses: Preliminary results.

BMC Vet Res 2019 Jan 16;15(1):29. Epub 2019 Jan 16.

Faculty of Veterinary Medicine, University of Leipzig, Department for Horses, Leipzig, Germany.

Background: Despite appropriate medical therapy, many horses with equine recurrent uveitis continue to suffer from recurrent bouts of inflammation. Surgical intervention via the pars plana vitrectomy or suprachoroidal cyclosporine implant placement may control and/or prevent recurrences, however, these procedures may be contraindicated, unavailable, or declined by an owner. Thus, an effective adjunctive treatment option may help to improve the clinical outcomes in those situations. Read More

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http://dx.doi.org/10.1186/s12917-018-1722-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335700PMC
January 2019
3 Reads

Predicting career sector intent and the theory of planned behaviour: survey findings from Australian veterinary science students.

BMC Vet Res 2019 Jan 15;15(1):27. Epub 2019 Jan 15.

Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Melbourne, Australia.

Background: Producing graduates for a breadth of sectors is a priority for veterinary science programs. Undergraduate career intentions represent de-facto 'outcome' measures of admissions policy and curricula design, as intentions are strong predictors of eventual behaviour. Informed by Ajzen's Theory of Planned Behaviour, this study aimed to identify if contextually relevant attitudes and self-ratings affect student intentions for veterinary career sectors. Read More

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https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-
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http://dx.doi.org/10.1186/s12917-018-1725-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334407PMC
January 2019
6 Reads

Pathogenicity and immunogenicity of attenuated porcine epidemic diarrhea virus PC22A strain in conventional weaned pigs.

BMC Vet Res 2019 Jan 11;15(1):26. Epub 2019 Jan 11.

Food Animal Health Research Program, Ohio Agricultural Research and Development Center, Colleage of Food, Agricultural and Environmental Sciences, Department of Veterinary Preventive Medicine, College of Veterinary Medicine, The Ohio State University, Wooster, OH, USA.

Background: Porcine epidemic diarrhea virus (PEDV) causes diarrhea in all ages of pigs with 50-100% mortality rates in neonatal piglets. In the United States, inactivated and subunit PEDV vaccines for pregnant sows are available, but fail to induce sufficient protection in neonatal piglets farrowed from PEDV naïve sows. A safe and efficacious live attenuated vaccine that can prime mucosal immune responses is urgently needed. Read More

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https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-
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http://dx.doi.org/10.1186/s12917-018-1756-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329175PMC
January 2019
6 Reads

Bcl-2 expression and prognostic significance in feline invasive mammary carcinomas: a retrospective observational study.

BMC Vet Res 2019 Jan 10;15(1):25. Epub 2019 Jan 10.

AMaROC, Oniris (Nantes Atlantic College of Veterinary Medicine, Food Science and Engineering), Oniris site Chantrerie, CS40706, 44307, Cedex 3, Nantes, France.

Background: Cats spontaneously develop invasive mammary carcinomas with high clinical aggressiveness, and are considered relevant animal models for human breast cancer. Bcl-2 is an anti-apoptotic pro-survival protein, whose expression is associated with a favorable outcome in human breast cancer. The aim of our study was to determine the frequency of Bcl-2 expression in feline invasive mammary carcinomas (FMCs), its relationship with other clinicopathologic variables, and its prognostic value. Read More

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http://dx.doi.org/10.1186/s12917-018-1772-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329127PMC
January 2019
9 Reads

High prevalence of persistently infected animals from bovine viral diarrhea in Colombian cattle.

BMC Vet Res 2019 Jan 10;15(1):23. Epub 2019 Jan 10.

Departamento de Microbiología, Pontificia Universidad Javeriana, Carrera 7 No. 40 - 62, Bogotá, Colombia.

Background: Bovine Viral Diarrhea Virus (BVDV) is associated with gastrointestinal, respiratory and reproductive diseases of livestock across the world that causes continuous economic losses in the cattle industry. This virus can establish a persistent infection (PI) in calves after the fetal infection, making BVDV positive catle carriers and primary reservoirs which will constantly transmit the virus to healthy and new-born animals. For this reason, the detection of the PI animals in herds is the first line of prevention of the viral infection. Read More

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http://dx.doi.org/10.1186/s12917-018-1769-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327412PMC
January 2019
3 Reads

Detection of endoplasmic reticulum stress and the unfolded protein response in naturally-occurring endocrinopathic equine laminitis.

BMC Vet Res 2019 Jan 10;15(1):24. Epub 2019 Jan 10.

Department of Clinical Studies/New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square, PA, 19348, USA.

Background: Laminitis is often associated with endocrinopathies that cause hyperinsulinemia and is also induced experimentally by hyperinsulinemia, suggesting that insulin initiates laminitis pathogenesis. Hyperinsulinemia is expected to activate pro-growth and anabolic signaling pathways. We hypothesize that chronic over-stimulation of these pathways in lamellar tissue results in endoplasmic reticulum stress, contributing to tissue pathology, as it does in human metabolic diseases. Read More

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http://dx.doi.org/10.1186/s12917-018-1748-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327420PMC
January 2019
2 Reads

Feline pemphigus foliaceus: original case series and a comprehensive literature review.

BMC Vet Res 2019 Jan 9;15(1):22. Epub 2019 Jan 9.

Murdoch University Veterinary Hospital, School of Veterinary and Biomedical Science, Murdoch University, Murdoch, WA, Australia.

Background: Since the first description of feline pemphigus foliaceus (PF) more than 30 years ago, numerous case reports have been published, while larger case series have remained rare. This large body of information, if extrapolated, could address clinical discrepancies and expand our knowledge about the treatment of feline PF. This manuscript reviews cases of feline PF published between 1950 and 2016 and adds additional 35 original cases to provide further insight into the clinical aspect and treatment outcome of this disease. Read More

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http://dx.doi.org/10.1186/s12917-018-1739-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327590PMC
January 2019
11 Reads

Abdominal volume computed tomography assessment of body composition in dogs.

BMC Vet Res 2019 Jan 8;15(1):21. Epub 2019 Jan 8.

U-Vet Animal Hospital, Faculty of Veterinary and Agricultural Sciences, University of Melbourne, 250 Princes Highway, Werribee, Victoria, 3030, Australia.

Background: Computed tomography (CT) has been used to estimate body composition and determine tissue distribution in dogs, despite limited validation. This may introduce error into estimates of body composition studies and its effect on health in dogs. Further, the modality has not been validated against dual-energy X-ray absorptiometry (DXA) or over a wide range of dog breeds, ages and sexes. Read More

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http://dx.doi.org/10.1186/s12917-018-1768-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325834PMC
January 2019
2 Reads

Characterization of the responses of the caspase 2, 3, 6 and 8 genes to immune challenges and extracellular ATP stimulation in the Japanese flounder (Paralichthys olivaceus).

BMC Vet Res 2019 Jan 8;15(1):20. Epub 2019 Jan 8.

Tianjin Key Laboratory of Animal and Plant Resistance, College of Life Sciences, Tianjin Normal University, 393 West Binshui Road, Tianjin, 300387, Xiqing District, China.

Background: Caspases are a family of conserved intracellular cysteine-dependent aspartate-specific cysteine proteases that play important roles in regulating cell death and inflammation. Our previous study revealed the importance of the inflammatory caspase 1 gene in extracellular ATP-mediated immune signaling in Japanese flounder, Paralichthys olivaceus. To explore the potential roles of other caspases in P. Read More

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http://dx.doi.org/10.1186/s12917-018-1763-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325855PMC
January 2019
6 Reads
1.777 Impact Factor

Laparoscopic ovariectomy in dogs in late gestation.

BMC Vet Res 2019 Jan 8;15(1):19. Epub 2019 Jan 8.

Dr Chariar's Pet Specialty Clinic, Thane, Maharashtra, 400607, India.

Background: Surgical sterilization of stray dogs is the most widely used technique to control stray dog population. Although ovariectomy is an effective technique for elective sterilization of female dogs, most stray dog population control programs generally utilize ovariohysterectomy for spaying female dogs. In the context of stray dog sterilization, laparoscopic ovariectomy has been utilized and reported to be cost-effective compared to programs utilizing open surgical approaches. Read More

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http://dx.doi.org/10.1186/s12917-018-1770-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325880PMC
January 2019
3 Reads

Drivers, alternatives, knowledge, and perceptions towards antimicrobial use among Tennessee beef cattle producers: a qualitative study.

BMC Vet Res 2019 Jan 7;15(1):16. Epub 2019 Jan 7.

Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, 2407 River Drive, Knoxville, TN, 37996, USA.

Background: In recent years, there has been an increased awareness of antimicrobial resistance in both animals and humans, which has triggered concerns over non-judicious antimicrobial use. In the United States, antimicrobial use in food-producing animals for growth promotion or improved feed efficiency is perceived as non-judicious. To facilitate judicious antimicrobial use, the United States Food and Drug Administration implemented the Veterinary Feed Directive, effective from January 1, 2017. Read More

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http://dx.doi.org/10.1186/s12917-018-1731-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323766PMC
January 2019
5 Reads

Prevalence and risk factors of bovine schistosomiasis in Northwestern Ethiopia.

BMC Vet Res 2019 Jan 7;15(1):12. Epub 2019 Jan 7.

Department of Biology, Jigjiga University, P.O. Box- 1020, Jijiga, Ethiopia.

Background: Parasitic diseases remain major bottle neck to livestock development in developing nations. The objective of this study was to determine the prevalence and associated risk factors of Bovine Schistosomiasis (BS) in South Achefer District, northwestern Ethiopia.

Methods: A cross-sectional copro-parasitological and observational study was conducted in South Achefer district from October, 2015 to April, 2016. Read More

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http://dx.doi.org/10.1186/s12917-018-1757-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322276PMC
January 2019
8 Reads

Molecular investigation of the colicinogenic Escherichia coli strains that are capable of inhibiting E. coli O157:H7 in vitro.

BMC Vet Res 2019 Jan 7;15(1):14. Epub 2019 Jan 7.

Molecular Microbiology Research Group, Faculty of Veterinary Medicine, Shahid Bahonar University of Kerman, Kerman, Iran.

Background: Escherichia coli O157:H7 is a highly virulent human pathogen with severe consequences following infection, which claims many lives worldwide. A suggested method for controlling this bacterium is the competitive elimination through using probiotic bacteria that prevent its colonization. Some nonpathogenic E. Read More

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http://dx.doi.org/10.1186/s12917-018-1771-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323730PMC
January 2019
2 Reads

Oral faecal microbiota transplantation for the treatment of Clostridium difficile-associated diarrhoea in a dog: a case report.

BMC Vet Res 2019 Jan 7;15(1):11. Epub 2019 Jan 7.

Cooperative Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, 3-5-8 Saiwaicho, Fuchu, Tokyo, 183-8509, Japan.

Background: Successful clinical outcomes of faecal microbiota transplantation (FMT) for recurrent Clostridium difficile infection have been reported in humans and a marmoset. However, it has been unclear whether oral FMT was effective for the treatment of C. difficile-associated diarrhoea in dogs. Read More

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https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-
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http://dx.doi.org/10.1186/s12917-018-1754-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322325PMC
January 2019
8 Reads

Immunization of young heifers with staphylococcal immune evasion proteins before natural exposure to Staphylococcus aureus induces a humoral immune response in serum and milk.

BMC Vet Res 2019 Jan 7;15(1):15. Epub 2019 Jan 7.

Department of Large Animal Health, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.

Background: Staphylococcus aureus, a leading cause of mastitis in dairy cattle, causes severe mastitis and/or chronic persistent infections with detrimental effects on the cows' wellbeing, lifespan and milk production. Despite years of research there is no effective vaccine against S. aureus mastitis. Read More

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http://dx.doi.org/10.1186/s12917-018-1765-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323680PMC
January 2019
2 Reads

Correction to: Brucellosis seroprevalence in ovine and caprine flocks in China during 2000-2018: a systematic review and meta-analysis.

BMC Vet Res 2019 01 8;15(1):18. Epub 2019 Jan 8.

College of Animal Science & Veterinary Medicine, Heilongjiang Bayi Agricultural University, No.5, XinFeng Rd., Saertu District, Daqing City, 163319, Heilongjiang Province, China.

The original article [1] contained a minor error whereby Table 1 was typeset incorrectly. Read More

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https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-
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http://dx.doi.org/10.1186/s12917-018-1749-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323784PMC
January 2019
5 Reads

Critically appraised topic for the most effective and safe treatment for canine generalised demodicosis.

BMC Vet Res 2019 Jan 7;15(1):17. Epub 2019 Jan 7.

Department of Veterinary Medicine (DIMEVET), University of Milan, Via G. Celoria 10, 20133, Milan, Italy.

Background: Canine generalised demodicosis is an inflammatory parasitic skin disease caused by an excessive proliferation of Demodex spp. Generalized demodicosis is a severe skin disease, that can be life threatening if not treated properly. Many of the current treatment options are not licensed for the treatment of generalised demodicosis, it have a low safety margin and may be poorly efficacious and time-consuming for the owner; there is a need for a safe, efficacious treatment for canine demodicosis. Read More

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https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-
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http://dx.doi.org/10.1186/s12917-018-1767-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323682PMC
January 2019
3 Reads

Comparison of the sensitivity of three cell cultures to ORFV.

BMC Vet Res 2019 Jan 7;15(1):13. Epub 2019 Jan 7.

State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Science, Lanzhou, 730046, China.

Background: Contagious ecthyma (CE) appears in the countries and regions containing goat and sheep farms, and it is considered a global epidemic. CE not only severely endangers the healthy development of the sheep and goat industries but also threatens human health. For viral infectious diseases, fast and effective isolation and culture of the pathogen is critical for CE diagnosis, and for disease prevention and control. Read More

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http://dx.doi.org/10.1186/s12917-018-1760-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322270PMC
January 2019
3 Reads