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    2320 results match your criteria BMC Veterinary Research [Journal]

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    Correction to: Antibiotic resistance pattern and virulence genes content in avian pathogenic Escherichia coli (APEC) from broiler chickens in Chitwan, Nepal.
    BMC Vet Res 2018 May 22;14(1):166. Epub 2018 May 22.
    Center for Biotechnology, Agriculture and Forestry University, Rampur, Chitwan, Nepal.
    The original article [1] contains errors in author panels and their contributions, errors in both the Methodology and the Results sections, and errors with respect to funding sources. The affected sections of the manuscript and their respective regions of corrected text can be viewed ahead. Read More

    Diagnostic tools of caprine and ovine anaplasmosis: a direct comparative study.
    BMC Vet Res 2018 May 22;14(1):165. Epub 2018 May 22.
    Department of Experimental Pathology, Immunology & Microbiology, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.
    Background: The diagnosis of anaplasmosis is rather conflicting with other haemoprotozoans. Hence, the study aimed to compare and evaluate the efficiency of competitive ELISA (cELISA), indirect fluorescence antibody (IFA), and Polymerase chain reaction (PCR) for precise diagnosis of Anaplasma spp. and to assess their concordance with microscopic examination (ME). Read More

    Comparison of three imaging modalities used to evaluate bone healing after tibial tuberosity advancement in cranial cruciate ligament-deficient dogs and comparison of the effect of a gelatinous matrix and a demineralized bone matrix mix on bone healing - a pilot study.
    BMC Vet Res 2018 May 22;14(1):164. Epub 2018 May 22.
    Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, 32610-0126, USA.
    Background: Bone healing and assessment of the state of bone bridging is an important part of clinical orthopedics, whether for fracture healing or for follow up of osteotomy procedures. Tibial tuberosity advancement (TTA) is designed to restore stability in cruciate deficient stifle joints by advancing the tuberosity while creating an osteotomy gap. The current study aims to: 1) compare three different imaging modalities to assess bone healing: ultrasound, radiographs and computed tomography (CT) and, to 2) compare the effect of a gelatinous matrix (GM) versus a demineralized bone matrix mix (DBM mix) on bone healing and bridging of this osteotomy gap in 10 otherwise healthy client-owned dogs with cranial cruciate ligament insufficiency. Read More

    Investigating porcine parvoviruses genogroup 2 infection using in situ polymerase chain reaction.
    BMC Vet Res 2018 May 21;14(1):163. Epub 2018 May 21.
    Department of Microbiology and Infectious Diseases, Faculty of Veterinary Science, Immunology, Szent István University, István u. 2, Budapest, 1078, Hungary.
    Background: Porcine parvovirus 2 (PPV2) was detected in swine serum without showing any relationship with disease. The emergence of the virus seemed to be a unique event until other genetically highly similar parvoviruses were identified in China and, later in 2012, the presence of the virus was also described in Europe. PPV2 is widely distributed in pig populations where it is suspected to be involved in respiratory conditions, based on its frequent detection in lung samples. Read More

    Rostral cranial fossa as a site for cerebrospinal fluid drainage - volumetric studies in dog breeds of different size and morphotype.
    BMC Vet Res 2018 May 18;14(1):162. Epub 2018 May 18.
    Department of Surgery, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, Pl. Grunwaldzki 51, 50-366, Wroclaw, Poland.
    Background: Hydrocephalus is a multifactorial condition, whose aetiology is not fully understood. Congenital hydrocephalus frequently occurs in small and brachycephalic dog breeds. Although it is widely accepted that the cribriform plate located in the rostral cranial fossa (RCF) is a site of cerebrospinal fluid (CSF) drainage, the RCF has not been studied extensively. Read More

    Geographic distribution and molecular analysis of porcine reproductive and respiratory syndrome viruses circulating in swine farms in the Republic of Korea between 2013 and 2016.
    BMC Vet Res 2018 May 16;14(1):160. Epub 2018 May 16.
    Viral Disease Division, Animal and Plant Quarantine Agency, Gimcheon, 39660, Republic of Korea.
    Background: Porcine reproductive and respiratory syndrome virus (PRRSV) causes devastating disease characterized by reproductive failure and respiratory problems in the swine industry. To understand the recent prevalence and genetic diversity of field PRRSVs in the Republic of Korea, open reading frames (ORFs) 5 and 7 of PRRSV field isolates from 631 PRRS-affected swine farms nationwide in 2013-2016 were analyzed along with 200 Korean field viruses isolated in 2003-2010, and 113 foreign field and vaccine strains.

    Results: Korean swine farms were widely infected with PRRSVs of a single type (38. Read More

    Inflammatory pattern of the infrapatellar fat pad in dogs with canine cruciate ligament disease.
    BMC Vet Res 2018 May 16;14(1):161. Epub 2018 May 16.
    Division of Small Animal Surgery and Orthopaedics, Department of clinical veterinary medicine, Vetsuisse Faculty, University of Bern, Länggassstrasse 128, 3012, Bern, Switzerland.
    Background: Despite the importance of inflammation during the pathogenesis of cranial cruciate ligament disease (CCLD) in dogs and despite the latest knowledge suggesting a significant role of adipose tissue in osteoarthritis, the infrapatellar fat pad (IFP) was up to now mostly disregarded in veterinary investigations. In the present study, the inflammatory activity of the IFP, the main adipose structure within the stifle joint, was thoroughly investigated to evaluate its potential impact in the pathogenesis of this common disease of our canine companions. Samples of IFP, subcutaneous adipose tissue (ScAT) of the thigh and synovial fluid in both diseased (n = 36) and healthy control (n = 23) dogs were tested for their immune cell composition but also for interleukins (IL-1β, IL-6, IL-8, IL-10), degradative enzymes (MMP-1, MMP-3, MMP-13, TIMP-2, iNOS) and adipokines (leptin and adiponectin). Read More

    Insemination with border disease virus-infected semen results in seroconversion in cows but not persistent infection in fetuses.
    BMC Vet Res 2018 May 16;14(1):159. Epub 2018 May 16.
    Institute for Virology and Immunology, and Department of Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
    Background: This study examined various health variables in cows after artificial insemination with Border disease virus (BDV)-infected semen and the occurrence of persistent infection in ensuing fetuses. Five cows were inseminated (day 0) with BDV-infected semen as well as with semen from a fertile Eringer bull. One cow, inseminated with virus-free semen only, served as a control. Read More

    Cyclooxygenase-2 immunoexpression in intestinal epithelium and lamina propria of cats with inflammatory bowel disease and low grade alimentary lymphoma.
    BMC Vet Res 2018 May 15;14(1):158. Epub 2018 May 15.
    Departament de Medicina i Cirurgia Animals, Universitat Autònoma de Barcelona, 08193, Barcelona, Spain.
    Background: Cyclooxygenase 2 (COX-2) is an inducible isoform by cellular activation, proinflammatory cytokines and growth factors. The aims of the current study were to evaluate COX-2 immunoexpression in epithelial and lamina propria (LP) of cats with inflammatory bowel disease (IBD) and low grade alimentary lymphoma (LGAL), as well as to correlate them with clinical signs and histopathological scoring. Cats diagnosed with IBD and LGAL (2007-2013) were included in the current study. Read More

    Auto-immune skin diseases in animals: time to reclassify and review after 40 years.
    BMC Vet Res 2018 May 11;14(1):157. Epub 2018 May 11.
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, 27606, USA.
    It has been more than 40 years since the dual descriptions of canine pemphigus vulgaris. Over the ensuing four decades, the reports of-mostly canine-novel autoimmune skin diseases (AISDs) have progressed in successive waves separated by long periods of quiescence. This Editorial introduces a series of comprehensive review papers on the various canine and feline AISDs. Read More

    Salivary alpha-amylase activity and cortisol in horses with acute abdominal disease: a pilot study.
    BMC Vet Res 2018 May 10;14(1):156. Epub 2018 May 10.
    Interdisciplinary Laboratory of Clinical Analysis (Interlab-UMU), Veterinary School, Campus of Excellence Mare Nostrum, University of Murcia, 30100, Espinardo, Murcia, Spain.
    Background: The aim of this study was to evaluate salivary alpha-amylase (sAA), considered a non-invasive biomarker for sympathetic nervous system (SNS) activity, and salivary cortisol as possible pain-induced stress biomarker, in horses with acute abdominal disease. Therefore, a prospective observational study was performed in which both biomarkers were analyzed in a group of horses with acute abdomen syndrome, and compared with a group of healthy control horses by an unpaired Student's t-test. In addition, the possible relationship between both biomarkers, the score in Equine Acute Abdominal Pain scales version 1 (EAAPS-1 scale), Heart Rate (HR) and Respiratory Rate (RR), plasma lactate, the systemic inflammatory response syndrome (SIRS) score and serum amyloid A (SAA) concentration was assessed by a Spearman correlation test. Read More

    Immunohistochemical characterization of tuberculous lesions in sheep naturally infected with Mycobacterium bovis.
    BMC Vet Res 2018 May 4;14(1):154. Epub 2018 May 4.
    SERIDA, Servicio Regional de Investigación y Desarrollo Agroalimentario, Centro de Biotecnología Animal, 33394, Gijón, Asturias, Spain.
    Background: Sheep have been traditionally considered as less susceptible to Mycobacterium bovis (Mbovis) infection than other domestic ruminants such as cattle and goats. However, there is increasing evidence for the role of this species as a domestic Mbovis reservoir, mostly when sheep share grazing fields with infected cattle and goats. Nevertheless, there is a lack of information about the pathogenesis and the immune response of Mbovis infection in sheep. Read More

    Characterization of the DNA binding activity of structural protein VP1 from chicken anaemia virus.
    BMC Vet Res 2018 May 4;14(1):155. Epub 2018 May 4.
    Department of Chinese Pharmaceutical Science and Chinese Medicine Resources, China Medical University, 91, Hsueh-Shih Road, Taichung, Taiwan.
    Background: Chicken anaemia virus (CAV) is commonly found in poultry. VP1 is the sole structural protein of CAV, which is the major component responsible for capsid assembly. The CAV virion consists of the VP1 protein and a viral genome. Read More

    Molecular characterization and expression patterns of a non-mammalian toll-like receptor gene (TLR21) in larvae ontogeny of common carp (Cyprinus carpio L.) and upon immune stimulation.
    BMC Vet Res 2018 May 3;14(1):153. Epub 2018 May 3.
    Shandong Provincial Key Laboratory of Animal Resistance Biology, College of Life Sciences, Shandong Normal University, No. 88 East Wenhua Road, Jinan, 250014, People's Republic of China.
    Background: In the host innate immune system, various pattern recognition receptors (PRRs) recognize conserved pathogen-associated molecular patterns (PAMPs) and represent an efficient first line of defense against invading pathogens. Toll-like receptors (TLRs) are a major class of PRRs, which are able to recognize a wide range of PAMPs and play a central role in initiating innate immune responses. TLR21 is one of the non-mammalian TLRs identified in some bird and fish species. Read More

    Inhibitory effects of sodium pentosan polysulfate on formation and function of osteoclasts derived from canine bone marrow.
    BMC Vet Res 2018 May 2;14(1):152. Epub 2018 May 2.
    Department of Veterinary Clinical Sciences, Laboratory of Veterinary Surgery, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, 060-0818, Japan.
    Background: Sodium pentosan polysulfate (NaPPS) was testified as a chondroprotective drug in with a detailed rationale of the disease-modifying activity. This study was undertaken to determine whether anti-osteoarthritis drug, NaPPS inhibited osteoclasts (OC) differentiation and function. Canine bone marrow mononuclear cells (n = 6) were differentiated to OC by maintaining with receptor activator of nuclear factor kappa B ligand (RANKL) and macrophage colony-stimulating factor (M-CSF) for up to 7 days with the treatment of NaPPS at concentration of 0, 0. Read More

    Comparison of the virulence of three H3N2 canine influenza virus isolates from Korea and China in mouse and Guinea pig models.
    BMC Vet Res 2018 May 2;14(1):149. Epub 2018 May 2.
    College of Pharmacy, Korea University, Sejong, 339-700, South Korea.
    Background: Avian-origin H3N2 canine influenza virus (CIV) has been the most common subtype in Korea and China since 2007. Here, we compared the pathogenicity and transmissibility of three H3N2 CIV strains [Chinese CIV (JS/10), Korean CIV (KR/07), and Korean recombinant CIV between the classic H3N2 CIV and the pandemic H1N1 virus (MV/12)] in BALB/c mouse and guinea pig models. The pandemic H1N1 (CA/09) strain served as the control. Read More

    The impact of Aloe vera and licorice extracts on selected mechanisms of humoral and cell-mediated immunity in pigeons experimentally infected with PPMV-1.
    BMC Vet Res 2018 May 2;14(1):148. Epub 2018 May 2.
    Department of Poultry Diseases, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, ul. Oczapowskiego 13/14, 10-719, Olsztyn, Poland.
    Background: The aim of the study was to evaluate the impact of herbal extracts on selected immunity mechanisms in clinically healthy pigeons and pigeons inoculated with the pigeon paramyxovirus type 1 (PPMV-1). For the first 7 days post-inoculation (dpi), an aqueous solution of Aloe vera or licorice extract was administered daily at 300 or 500 mg/kg body weight (BW). The birds were euthanized at 4, 7 and 14 dpi, and spleen samples were collected during necropsy. Read More

    Lower plasma trans-4-hydroxyproline and methionine sulfoxide levels are associated with insulin dysregulation in horses.
    BMC Vet Res 2018 May 2;14(1):146. Epub 2018 May 2.
    Institute of Animal Science, Faculty of Agricultural Sciences, University of Hohenheim, Fruwirthstraße 35, 70593, Stuttgart, Germany.
    Background: Insulin dysregulation in horses is a metabolic condition defined by high insulin concentrations in the blood and peripheral insulin resistance. This hyperinsulinemia is often associated with severe damage in the hooves, resulting in laminitis. However, we currently lack detailed information regarding the potential involvement of particular metabolic pathways in pathophysiological causes and consequences of equine insulin dysregulation. Read More

    Osteoarthritis of the temporomandibular joint in the Eastern Atlantic harbour seal (Phoca vitulina vitulina) from the German North Sea: a study of the lesions seen in dry bone.
    BMC Vet Res 2018 May 2;14(1):150. Epub 2018 May 2.
    Department of Biology, University of Hildesheim, Universitätsplatz 1, 31141, Hildesheim, Germany.
    Background: Pathological changes and resulting functional impairment of the temporomandibular joint (TMJ) can substantially affect physical condition, morbidity, and mortality of wildlife species. Analysis of TMJ disorders is therefore of interest for the characterization of the health status of populations of wild mammals. This paper, for the first time, analyses the prevalence of TMJ osteoarthritis (TMJ-OA) and the spectrum of osteoarthritic bone lesions of the TMJ in the Eastern Atlantic harbour seal (Phoca vitulina vitulina), applying a standardized scoring system. Read More

    Assessment of static posturography and pedobarography for the detection of unilateral forelimb lameness in ponies.
    BMC Vet Res 2018 May 2;14(1):151. Epub 2018 May 2.
    Departamento de Patología Animal, Instituto Universitario de Investigaciones Biomédicas Y Sanitarias, Universidad de Las Palmas de Gran Canaria, Arucas, Spain.
    Background: Static posturography and pedobarography are based on the detection of postural imbalance and, consequently, the pressure redistribution between limbs in lame subjects. These techniques have proven to be useful for the detection of lameness in humans and dogs. The main objective of this study was to test the suitability of static posturography and pedobarography in diagnosing lameness in ponies. Read More

    In vitro effects of aqueous extract from Maytenus senegalensis (Lam.) Exell stem bark on egg hatching, larval migration and adult worms of Haemonchus contortus.
    BMC Vet Res 2018 May 2;14(1):147. Epub 2018 May 2.
    Laboratory of Ethnopharmacology and Animal Health, Faculty of Agronomic Science University of Abomey Calavi, 01 P.O. Box 526, Cotonou, Benin.
    Background: Maytenus senegalensis is a common shrub which is scattered in tropical Africa. Different parts of this plant have been reported to be useful in traditional medicine against gastrointestinal disorders and intestinal worms. This study evaluated the anthelmintic activity of the aqueous stem bark extract of M. Read More

    Immunization with one Theileria parva strain results in similar level of CTL strain-specificity and protection compared to immunization with the three-component Muguga cocktail in MHC-matched animals.
    BMC Vet Res 2018 May 2;14(1):145. Epub 2018 May 2.
    International Livestock Research Institute, P.O. Box 30709, Nairobi, 00100, Kenya.
    Background: The tick-borne protozoan parasite Theileria parva causes a usually fatal cattle disease known as East Coast fever in sub-Saharan Africa, with devastating consequences for poor small-holder farmers. Immunity to T. parva, believed to be mediated by a cytotoxic T lymphocyte (CTL) response, is induced following natural infection and after vaccination with a live vaccine, known as the Infection and Treatment Method (ITM). Read More

    Virulent duck enteritis virus infected DEF cells generate a unique pattern of viral microRNAs and a novel set of host microRNAs.
    BMC Vet Res 2018 Apr 28;14(1):144. Epub 2018 Apr 28.
    Research Center of Avian Disease, College of Veterinary, Medicine of Sichuan Agricultural University, Wenjiang District, Chengdu, 611130, Sichuan Province, China.
    Background: Duck enteritis virus (DEV) belongs to the family Herpesviridae and is an important epornitic agent that causes economic losses in the waterfowl industry. The Chinese virulent (CHv) and attenuate vaccines (VAC) are two different pathogenic DEV strains. MicroRNAs (miRNAs) are a class of non-coding RNAs that regulate gene expression in viral infection. Read More

    Molecular characterization of a porcine teschovirus HuN-1 isolate proliferating in PK-15 cell.
    BMC Vet Res 2018 Apr 27;14(1):142. Epub 2018 Apr 27.
    Shanghai Key Laboratory of Veterinary Biotechnology, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, 200240, China.
    Background: Porcine teschoviruses (PTVs) are small non-enveloped viruses with single-stranded, positive sense genomic RNA, belonging to the family Picornaviridae. Natural infections of teschoviruses are limited to pigs.

    Results: In this study, a PTV HuN-1 was found that it could be proliferated in PK-15 cell, and it came from the pig fecal samples from Hunan province, in central China. Read More

    Comparison of the fecal microbiota of domestic commercial meat, laboratory, companion, and shelter rabbits (Oryctolagus cuniculi).
    BMC Vet Res 2018 Apr 27;14(1):143. Epub 2018 Apr 27.
    Department of Pathobiology, University of Guelph, Guelph, ON, N1G 2W1, Canada.
    Background: Rabbits are cecotrophic, hindgut-fermenters that rely heavily on their gastrointestinal microbiota for optimal digestion of plant-based diets. Dysbiosis, caused by disruption of the gastrointestinal microbiota, is known to predispose rabbits to rabbit enteritis complex (REC), a major cause of morbidity and mortality. The objectives of this study were to describe the fecal microbiota of domestic rabbits from a variety of settings (commercial meat, companion, laboratory, and shelter) and to identify how factors such as age, season, and routine antimicrobial use affect the fecal microbiota composition. Read More

    Responses to dietary levels of methionine in broilers medicated or vaccinated against coccidia under Eimeria tenella-challenged condition.
    BMC Vet Res 2018 Apr 25;14(1):140. Epub 2018 Apr 25.
    Sichuan Giant Star Company's Experimental Station, Leshan, Sichuan, 614800, People's Republic of China.
    Background: Coccidiosis is a prevalent problem in chicken production. Dietary addition of coccidiostats and vaccination are two approaches used to suppress coccidia in the practical production. Methionine (Met) is usually the first limiting amino acid that plays important roles in protein metabolism and immune functions in chickens. Read More

    In vitro quality control analysis after processing and during storage of feline packed red blood cells units.
    BMC Vet Res 2018 Apr 27;14(1):141. Epub 2018 Apr 27.
    Department of Animal Medicine and Surgery, Veterinary Faculty, Autonomous University of Barcelona, 08193, Barcelona, Spain.
    Background: During the storage of packed red blood cells (pRBC), packed cell volume (PCV), bacterial contamination and percentage of haemolysis [percentage of free haemoglobin (HGB) in relation to the total HGB] are important quality parameters. Both PCV and haemolysis are indicators of the cellular integrity of stored units. There are no published experimental studies that evaluated these parameters during storage of feline pRBC using SAGM (adenine, dextrose, mannitol and sodium chloride) as the additive solution. Read More

    Tween-20 transiently changes the surface morphology of PK-15 cells and improves PCV2 infection.
    BMC Vet Res 2018 Apr 24;14(1):138. Epub 2018 Apr 24.
    Institute of Veterinary Immunology & Engineering, Jiangsu Academy of Agricultural Sciences, Nanjing, 210014, China.
    Background: Low concentrations of nonionic surfactants can change the physical properties of cell membranes, and thus and in turn increase drug permeability. Porcine circovirus 2 (PCV2) is an extremely slow-growing virus, and PCV2 infection of PK-15 cells yields very low viral titers. The present study investigates the effect of various nonionic surfactants, namely, Tween-20, Tween-28, Tween-40, Tween-80, Brij-30, Brij-35, NP-40, and Triton X-100 on PCV2 infection and yield in PK-15 cells. Read More

    Elevated urinary excretion of free pyridinoline in Friesian horses suggests a breed-specific increase in collagen degradation.
    BMC Vet Res 2018 Apr 25;14(1):139. Epub 2018 Apr 25.
    Laboratory of Veterinary Pathology, Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
    Background: Friesian horses are known for their high inbreeding rate resulting in several genetic diseases such as hydrocephaly and dwarfism. This last decade, several studies focused on two other presumed hereditary traits in Friesian horses: megaoesophagus and aortic rupture. The pathogenesis of these diseases remains obscure but an important role of collagen has been hypothesized. Read More

    Immunogenicity evaluation of inactivated virus and purified proteins of porcine circovirus type 2 in mice.
    BMC Vet Res 2018 Apr 23;14(1):137. Epub 2018 Apr 23.
    Jilin Provincial Key Laboratory of Animal Embryo Engineering, College of Animal Sciences, Jilin University, Changchun, Jilin, 130062, China.
    Background: Vaccination is considered as an effective and economical way to against PCV2 infection. However, some of commercial available vaccines are based on inactivated viruses, while the others are based on purified protein of PCV2. In the present study, we aimed to compare the immunogenicity of inactivated virus and purified proteins of porcine circovirus type 2 in mice. Read More

    Inflammatory mechanism of Rumenitis in dairy cows with subacute ruminal acidosis.
    BMC Vet Res 2018 Apr 19;14(1):135. Epub 2018 Apr 19.
    Key Laboratory of Zoonosis, Ministry of Education, College of Veterinary Medicine, Jilin University, 5333 Xi'an Road, Changchun, Jilin, 130062, China.
    Background: Subacute ruminal acidosis (SARA) is a metabolic disease in high-producing dairy cattle, and is accompanied by rumenitis. However, the mechanism of rumenitis remains unclear. Therefore, the aim of this study was to investigate the molecular mechanism of rumenitis in dairy cows with SARA. Read More

    Efficacy of live attenuated porcine reproductive and respiratory syndrome virus 2 strains to protect pigs from challenge with a heterologous Vietnamese PRRSV 2 field strain.
    BMC Vet Res 2018 Apr 19;14(1):133. Epub 2018 Apr 19.
    Institute for Veterinary Disease Control, AGES, Robert-Koch-Gasse 17, 2340, Mödling, Austria.
    Background: Effective vaccines against porcine reproductive and respiratory syndrome virus (PRRSV), especially against highly pathogenic (HP) PRRSV are still missing. The objective of this study was to evaluate the protective efficacy of an experimental live attenuated PRRSV 2 vaccine, composed of two strains, against heterologous challenge with a Vietnamese HP PRRSV 2 field strain. For this reason, 20 PRRSV negative piglets were divided into two groups. Read More

    Modulation of ovine SBD-1 expression by Saccharomyces cerevisiae in ovine ruminal epithelial cells.
    BMC Vet Res 2018 Apr 19;14(1):134. Epub 2018 Apr 19.
    Veterinary Medicine College of Inner Mongolia Agricultural University, Hohhot, 010018, People's Republic of China.
    Background: The ovine rumen is involved in host defense responses and acts as the immune interface with the environment. The ruminal mucosal epithelium plays an important role in innate immunity and secretes antimicrobial innate immune molecules that have bactericidal activity against a variety of pathogens. Defensins are cationic peptides that are produced by the mucosal epithelia and have broad-spectrum antimicrobial activity. Read More

    On-farm storage of livestock vaccines may be a risk to vaccine efficacy: a study of the performance of on-farm refrigerators to maintain the correct storage temperature.
    BMC Vet Res 2018 Apr 19;14(1):136. Epub 2018 Apr 19.
    School of Veterinary Science, University of Bristol, Langford House, Langford, Bristol, BS40 5DU, UK.
    Background: Livestock vaccines (LV) are often stored on-farm, in a refrigerator (fridge), prior to use and little is documented about the storage conditions during this period. As the quality of a vaccine can be impaired by storage at an incorrect temperature, the present study aimed to evaluate the on-farm performance of farm fridges to maintain the correct storage temperature. From January to August 2014, temperature data loggers were placed on selected farms fridges used to store LV (n = 20) in South-West England. Read More

    Cutaneous lupus erythematosus in dogs: a comprehensive review.
    BMC Vet Res 2018 Apr 18;14(1):132. Epub 2018 Apr 18.
    Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.
    Since the first description of discoid lupus erythematosus (LE) in two dogs in 1979, the spectrum of canine cutaneous lupus erythematosus (CLE) variants has expanded markedly.In this review, we first propose an adaptation of the Gilliam-Sontheimer classification of CLE for dogs. We then review the signalment, clinical signs, laboratory and histopathology and treatment outcome of the currently recognized variants of canine CLE, which are vesicular CLE, exfoliative CLE, mucocutaneous LE and facial or generalized discoid LE. Read More

    Herd-level seroprevalence of Fasciola hepatica and Ostertagia ostertagi infection in dairy cattle population in the central and northeastern Poland.
    BMC Vet Res 2018 Apr 17;14(1):131. Epub 2018 Apr 17.
    Laboratory of Veterinary Epidemiology and Economics, Faculty of Veterinary Medicine, Warsaw University of Life Sciences, Nowoursynowska 159c, 02-776, Warsaw, Poland.
    Background: Fasciola hepatica and Ostertagia ostertagi infections are widespread in cattle population of Europe, however data on their prevalence in Poland are only fragmentary. Therefore, the cross-sectional study was carried out to determine the herd-level seroprevalence of F. hepatica and O. Read More

    Exploratory field study on the effect of Porcine circovirus 2 (PCV2) sow vaccination on serological, virological and reproductive parameters in a PCV2 subclinically infected sow herd.
    BMC Vet Res 2018 Apr 16;14(1):130. Epub 2018 Apr 16.
    IRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.
    Background: This study sought to evaluate the effect of sow vaccination against Porcine circovirus 2 (PCV2) on reproductive parameters during two consecutive reproductive cycles. The study was performed in a PCV2 subclinical infected breeding herd (PCV2 circulation but absence of major reproductive problems). Ninety-four pregnant sows were primo-immunized with a commercial PCV2 vaccine and ninety-seven were injected with phosphate-buffered saline at 6 and 3 weeks before the first studied farrowing, and then boosted at 2 weeks before the second one. Read More

    Sub-chronic toxicopathological study of lantadenes of Lantana camara weed in Guinea pigs.
    BMC Vet Res 2018 Apr 13;14(1):129. Epub 2018 Apr 13.
    CSIR-IHBT, Palampur, Himachal Pradesh, India.
    Background: In the field conditions, animals regularly consume small quantities of lantana leaves either while grazing or due to mixing with regular fodder. The hypothesis of this study was that consumption of lantana toxins over a long period of time leads to progression of sub-clinical disease. Toxicopathological effects of sub-chronic (90 days) administration of lantadenes of L. Read More

    Correction to: Development and application of an indirect enzyme-linked immunosorbent assay based on recombinant capsid protein for the detection of mink circovirus infection.
    BMC Vet Res 2018 Apr 10;14(1):128. Epub 2018 Apr 10.
    Laboratory Animal and Comparative Medicine Unit, Harbin Veterinary Research Institute, The Chinese Academy of Agricultural Sciences, No. 678 Haping Rd, Harbin, 150069, China.
    The original article [1] contained an error whereby Fig. 2 had processed incorrectly. The correct version of Fig. Read More

    Rapid detection of three rabbit pathogens by use of the Luminex x-TAG assay.
    BMC Vet Res 2018 Apr 7;14(1):127. Epub 2018 Apr 7.
    Guangdong key laboratory of laboratory Animals, Guangzhou, China.
    Background: Domestic rabbits especially New Zealand white rabbits play an important role in biological research. The disease surveillance and quality control are essential to guarantee the results of animal experiments performed on rabbits. Rabbit hemorrhagic disease virus, rabbit rotavirus and Sendai virus are the important pathogens that needed to be eliminated. Read More

    Long term consistency and location specificity of equine gluteus medius muscle activity during locomotion on the treadmill.
    BMC Vet Res 2018 Apr 6;14(1):126. Epub 2018 Apr 6.
    Department for Companion Animals and Horses, University of Veterinary Medicine Vienna, Vienna, Austria.
    Background: The equine m. gluteus medius (GM) is the largest muscle of the horse, its main movement function is the extension of the hip joint. The objective of the present study was to measure equine GM activity in three adjacent locations on GM during walk and trot on a treadmill, in order to document potential differences. Read More

    S100A12 concentrations and myeloperoxidase activities are increased in the intestinal mucosa of dogs with chronic enteropathies.
    BMC Vet Res 2018 Apr 4;14(1):125. Epub 2018 Apr 4.
    Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, PO Box 57, Viikintie 49, 00014, Helsinki, Finland.
    Background: Intestinal mucosal S100A12 and myeloperoxidase (MPO) are inflammatory biomarkers in humans with inflammatory bowel disease (IBD). However, these biomarkers have not been studied in the intestinal mucosa of dogs with chronic enteropathies (CE), even though dogs with CE have increased S100A12 concentrations in feces and serum. This study investigated mucosal S100A12 concentrations and MPO activities in both dogs with CE and healthy Beagles. Read More

    Intraocular lens power calculation for the equine eye.
    BMC Vet Res 2018 Apr 3;14(1):123. Epub 2018 Apr 3.
    Stiftung Tierärztliche Hochschule Hannover, Klinik für Pferde, Bünteweg 9, 30559, Hannover, Germany.
    Background: Phacoemulsification and intraocular lens (IOL) implantation during cataract surgery in horses occur with increasing frequency. To reduce the postoperative refractive error it is necessary to determine the proper IOL power. In the present study retinoscopy, keratometry and ultrasonographic biometry were performed on 98 healthy equine eyes from 49 horses. Read More

    Multipulse transcranial electrical stimulation (TES): normative data for motor evoked potentials in healthy horses.
    BMC Vet Res 2018 Apr 3;14(1):121. Epub 2018 Apr 3.
    Department of Comparative Physiology and Biometrics, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820, Merelbeke, Belgium.
    Background: There are indications that transcranial electrical stimulation (TES) assesses the motor function of the spinal cord in horses in a more sensitive and reproducible fashion than transcranial magnetic stimulation (TMS). However, no normative data of TES evoked motor potentials (MEP) is available.

    Results: In this prospective study normative data of TES induced MEP wave characteristics (motor latency times (MLT); amplitude and waveform) was obtained from the extensor carpi radialis (ECR) and tibial cranialis (TC) muscles in a group of healthy horses to create a reference frame for functional diagnostic purposes. Read More

    First molecular detection and characterization of Marek's disease virus in red-crowned cranes (Grus japonensis): a case report.
    BMC Vet Res 2018 Apr 3;14(1):122. Epub 2018 Apr 3.
    MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
    Background: Marek's disease virus (MDV) resides in the genus Mardivirus in the family Herpesviridae. MDV is a highly contagious virus that can cause neurological lesions, lymphocytic proliferation, immune suppression, and death in avian species, including Galliformes (chickens, quails, partridges, and pheasants), Strigiformes (owls), Anseriformes (ducks, geese, and swans), and Falconiformes (kestrels).

    Case Presentation: In 2015, two red-crowned cranes died in Nanjing (Jiangsu, China). Read More

    Wearable sensor shown to specifically quantify pruritic behaviors in dogs.
    BMC Vet Res 2018 Apr 3;14(1):124. Epub 2018 Apr 3.
    AgLogica Holdings, Inc, Norcross, GA, USA.
    Background: Wearable technology is an exciting new field in humans and animals. In dogs activity monitors have helped to provide objective measurement tools where pet owner observation had been the only source of information. Previous research has focused on measuring overall activity versus rest. Read More

    Seroprevalence of anti-Toxoplasma gondii antibodies in Egyptian sheep and goats.
    BMC Vet Res 2018 Apr 2;14(1):120. Epub 2018 Apr 2.
    Laboratory of Immunology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
    Background: Toxoplasmosis is a zoonotic disease that affects a wide range of animals, including small ruminants. Sheep and goats are considered as biological indicators for the contamination of the environment with Toxoplasma gondii oocysts. In addition, in countries such as Egypt, where sheep and goat meat is frequently consumed, T. Read More

    Identification of immunologic and clinical characteristics that predict inflammatory response to C. Novyi-NT bacteriolytic immunotherapy.
    BMC Vet Res 2018 Apr 2;14(1):119. Epub 2018 Apr 2.
    Department of Veterinary Medicine and Surgery, Comparative Oncology Radiobiology and Epigenetics Laboratory, University of Missouri, College of Veterinary Medicine, 900 E. Campus Dr, Columbia, MO, 65203, USA.
    Background: Clostridium novyi-NT (CNV-NT), has shown promise as a bacterolytic therapy for solid tumors in mouse models and in dogs with naturally developing neoplasia. Factors that impact the immunologic response to therapy are largely unknown. The goal of this pilot study was to determine if plasma immune biomarkers, immune cell function, peripheral blood cytological composition and tumor characteristics including evaluation of a PET imaging surrogate of tumor tissue hypoxia could predict which dogs with naturally developing naïve neoplasia would develop an inflammatory response to CNV-NT. Read More

    Serological survey in wild boar (Sus scrofa) in Switzerland and other European countries: Sarcoptes scabiei may be more widely distributed than previously thought.
    BMC Vet Res 2018 Mar 27;14(1):117. Epub 2018 Mar 27.
    Centre for Fish and Wildlife Health, Vetsuisse Faculty, University of Bern, Länggass-Str. 122, Postfach, 3001, Bern, Switzerland.
    Background: Sarcoptic mange has recently emerged in wild boar in Switzerland, raising the question of the origin of the infection. The main aim of this study was to assess the extent of exposure of the wild boar populations to Sarcoptes scabiei in Switzerland, prior to and after the detection of mange cases, to determine whether the mite has been recently introduced into the populations concerned. We performed a serological survey using a commercially available ELISA and 1056 archived blood samples of free-ranging wild boar from Switzerland. Read More

    Experimental infection of pigs with H1 and H3 influenza A viruses of swine by using intranasal nebulization.
    BMC Vet Res 2018 Mar 27;14(1):115. Epub 2018 Mar 27.
    Division of Transboundary Animal Disease, National Institute of Animal Health, NARO, 3-1-5 Kannondai, Tsukuba, Ibaraki, 305-0856, Japan.
    Background: Experimental infection of pigs via direct intranasal or intratracheal inoculation has been mainly used to study the infectious process of influenza A viruses of swine (IAVs-S). Nebulization is known to be an alternative method for inoculating pigs with IAVs-S, because larger quantities of virus potentially can be delivered throughout the respiratory tract. However, there is very little data on the experimental infection of pigs by inhalation using nebulizer. Read More

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