1,072 results match your criteria BMC Urology[Journal]


Spontaneous bilateral renal pelvis rupture during CT in the absence of urinary tract obstruction: case report.

BMC Urol 2020 Jul 13;20(1):98. Epub 2020 Jul 13.

Ng Teng Fong General Hospital, Singapore, Singapore.

Background: Atraumatic renal pelvis rupture without pre-existing renal or ureteric pathology is an uncommon event. It is reported in the setting of acute urinary tract obstruction, most often secondary to ureteric calculi. Typical symptoms include acute flank pain and nausea, mimicking pyelonephritis or other causes of acute abdomen. Read More

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http://dx.doi.org/10.1186/s12894-020-00669-4DOI Listing

Intravesical gemcitabine versus mitomycin for non-muscle invasive bladder cancer: a systematic review and meta-analysis of randomized controlled trial.

BMC Urol 2020 Jul 13;20(1):97. Epub 2020 Jul 13.

Lanzhou University Second Hospital, Lanzhou City, Gansu Province, China.

Background: Mitomycin (MMC) has been frequently used as the compound for intravesical treatment. The relatively new pyrimidine analog gemcitabine (GEM) has exhibited anticancer effect on various solid cancers, such as the advanced bladder cancer. In this study, the GEM and MMC in treating non-muscle invasive bladder cancer (NMIBC) cases was compared through systemic review. Read More

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http://dx.doi.org/10.1186/s12894-020-00610-9DOI Listing

Rationale, design, and methods of electroencephalography-based investigation of the effects of oral desmopressin on improving slow-wave sleep time in nocturnal polyuria patients (the DISTINCT study): protocol for a single-arm, open-label, single-assignment trial.

BMC Urol 2020 Jul 11;20(1):96. Epub 2020 Jul 11.

Department of Urology, Nara Medical University, 840 Shijocho, Kashihara, Nara, 634-8522, Japan.

Background: Nocturia is one of the most bothersome lower urinary tract symptoms and often impairs sleep quality in the elderly. Although previous studies on nocturia have indicated that the successful treatment of nocturia improves sleep quality, most used questionnaires and activity devices to analyze sleep/wake patterns. Therefore, there is little information about the treatment effects of desmopressin on objective sleep quality. Read More

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http://dx.doi.org/10.1186/s12894-020-00668-5DOI Listing

Laparoscopy combining with ureteroscopy for horseshoe kidney accompanying with duplicate kidney and a ureteral calculus: a case report.

BMC Urol 2020 Jul 11;20(1):95. Epub 2020 Jul 11.

Department of Urology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400000, China.

Background: Horseshoe kidney (HSK) is a common renal fusion anomaly, occurring in about 1 in 400-600 individuals. In addition, the incidence of duplicated collecting system is about 0.8%. Read More

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http://dx.doi.org/10.1186/s12894-020-00667-6DOI Listing

LncRNA PLAC2 upregulates miR-663 to downregulate TGF-β1 and suppress bladder cancer cell migration and invasion.

BMC Urol 2020 Jul 10;20(1):94. Epub 2020 Jul 10.

Department of Urology, The first affiliated hospital of Wannan Medical College, No. 2, Zheshan West Road, Jinghu District, Wuhu City, Anhui Province, 241001, P. R. China.

Background: The roles of lncRNA PLAC2 in bladder cancer (BC) were explored.

Methods: The expression of PLAC2 in two types of tissue of BC patients was detected by RT-qPCR and the expression data were compared by paired t test. The 56 patients were staged according to the AJCC criteria, and 12, 15, 15 and 14 cases were classified into stage I-IV, respectively. Read More

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http://dx.doi.org/10.1186/s12894-020-00663-wDOI Listing

Is physical therapy effective following extracorporeal shockwave lithotripsy and retrograde intrarenal surgery: a meta-analysis and systematic review.

BMC Urol 2020 Jul 9;20(1):93. Epub 2020 Jul 9.

Urology, the First Affiliated Hospital of Guangzhou Medical University, Kangda Road 1, Haizhu District, Guangzhou, 510230, China.

Background: Physical therapy, including percussion, inversion, vibration and combinations, was clinically performed to improve the stone free rate (SFR) following lithotripsy procedures. However, physical therapy is not widely accepted in clinical practice owing to lack of high level evidence support and a standard protocol. The present meta-analysis aimed to evaluate the efficacy and safety of physical therapy in improving SFR following extracorporeal shockwave lithotripsy (ESWL) and retrograde intrarenal surgery (RIRS). Read More

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http://dx.doi.org/10.1186/s12894-020-00664-9DOI Listing

Tolerability and safety of urotainer® polihexanide 0.02% in catheterized patients: a prospective cohort study.

BMC Urol 2020 Jul 8;20(1):92. Epub 2020 Jul 8.

Department of Neurology & Neurorehabilitation, Kliniken Valens, Valens, Switzerland.

Background: In patients with indwelling bladder catheters for > 2 weeks, bacterial colonization is inevitable, leading to urinary tract infections or encrustations with subsequent catheter blockage. Currently, bladder irrigations are the most frequently used prophylactic means, but the best solution remains yet to be determined. In vitro studies demonstrate that polihexanide is a promising option for catheter irrigation, but no data about safety and tolerability exist. Read More

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http://dx.doi.org/10.1186/s12894-020-00650-1DOI Listing

Can we treat bladder cancer with intravesical Bacillus Calmette-Guerin in patients with prior tuberculosis infection? A population-based cohort study.

BMC Urol 2020 Jul 8;20(1):91. Epub 2020 Jul 8.

Division of Urology, Department of Surgery, Taipei City Hospital Zhongxiao Branch, Taipei, Taiwan.

Background: Intravesical bacillus Calmette-Guerin (BCG) therapy is the treatment of choice for patients with T1 or high-grade superficial bladder cancer or those with carcinoma in situ after transurethral resection. A personal history of tuberculosis infection has been viewed as a relative contraindication for BCG therapy, because it may increase the risk of complications or decrease the treatment effectiveness. We determined the safety and efficacy of intravesical BCG treatment for patients with prior tuberculosis infection by analyzing the data obtained from the National Health Insurance Research Database in Taiwan. Read More

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http://dx.doi.org/10.1186/s12894-020-00642-1DOI Listing

Observation of intracellular bacterial communities in urinary sediment using brightfield microscopy; a case report.

BMC Urol 2020 Jul 6;20(1):89. Epub 2020 Jul 6.

Laboratorio de Inmunobiología y Diagnóstico Molecular, Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Guerrero, Av. Lázaro Cárdenas s/n, University City, C.P.39090, Chilpancingo, Guerrero, Mexico.

Background: Urinary tract infections (UTIs) are usually related to the presence of Escherichia coli, a microorganism that adopts an intracellular life-style during the pathogenesis of cystitis. Evidence of the underlying mechanism in urothelial cells from urine samples has been reported. However, intracellular communities have not yet been described in squamous cells in fresh samples stained with Sternheimer-Malbin method, thus, we have provided these descriptions in this case report. Read More

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http://dx.doi.org/10.1186/s12894-020-00661-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339558PMC

Prognostic value of pretreatment neutrophil-to-lymphocyte ratio in renal cell carcinoma: a systematic review and meta-analysis.

BMC Urol 2020 Jul 6;20(1):90. Epub 2020 Jul 6.

Shanxi Medical University, Taiyuan, 030001, Shanxi, People's Republic of China.

Background: Numerous studies show that the pretreatment neutrophil-to-lymphocyte ratio (NLR) is associated with the prognosis of patients with RCC. However, their findings are inconsistent, urging us to explore the prognostic value of NLR in RCC patients.

Methods: This study was pre-registered in PROSPERO (CRD42020167131). Read More

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http://dx.doi.org/10.1186/s12894-020-00665-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339475PMC
July 2020
1.937 Impact Factor

A double blind, placebo-controlled randomized comparative study on the efficacy of phytosterol-enriched and conventional saw palmetto oil in mitigating benign prostate hyperplasia and androgen deficiency.

BMC Urol 2020 Jul 3;20(1):86. Epub 2020 Jul 3.

R&D Center for Excellence, Vidya Herbs Pvt. Ltd, #14A, Jigani I phase, Bangalore, Karnataka, 560 105, India.

Background: The present clinical trial was conducted to evaluate the efficacy and tolerability of a standardized saw palmetto oil containing 3% β-sitosterol in the treatment of benign prostate hyperplasia (BPH) and androgen deficiency.

Methods: Subjects aged 40-65 years with symptomatic BPH were randomized to 12-week double-blind treatment with 500 mg doses of β-sitosterol enriched saw palmetto oil, conventional saw palmetto oil and placebo orally in the form of capsules (n = 33 in each group). BPH severity was determined using the International Prostate Symptom Score (IPSS), uroflowmetry, serum measurement of prostate specific antigen (PSA), testosterone and 5α-reductase. Read More

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http://dx.doi.org/10.1186/s12894-020-00648-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333342PMC

Lower urinary tract symptoms in men: challenges to early hospital presentation in a resource-poor health system.

BMC Urol 2020 Jul 3;20(1):87. Epub 2020 Jul 3.

Department of Health Administration and Management, Faculty of Health Sciences and Technology, University of Nigeria Enugu Campus, Enugu, Nigeria.

Background: The point at which men seek medical care for lower urinary tract symptoms (LUTS) varies between individuals. Presentation to hospital with complications beyond LUTS appears prevalent in our setting. The aim of this survey is to assess from the community perspective in southeast Nigeria, the challenges to early presentation for medical evaluation for LUTS by men. Read More

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http://dx.doi.org/10.1186/s12894-020-00651-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333413PMC

Machine learning prediction of stone-free success in patients with urinary stone after treatment of shock wave lithotripsy.

BMC Urol 2020 Jul 3;20(1):88. Epub 2020 Jul 3.

Department of Urology, Chungnam National University College of Medicine, Chungnam National University Hospital, 282 Monwha-ro, Jung-gu, Daejeon, Republic of Korea, 35015.

Background: The aims of this study were to determine the predictive value of decision support analysis for the shock wave lithotripsy (SWL) success rate and to analyze the data obtained from patients who underwent SWL to assess the factors influencing the outcome by using machine learning methods.

Methods: We retrospectively reviewed the medical records of 358 patients who underwent SWL for urinary stone (kidney and upper-ureter stone) between 2015 and 2018 and evaluated the possible prognostic features, including patient population characteristics, urinary stone characteristics on a non-contrast, computed tomographic image. We performed 80% training set and 20% test set for the predictions of success and mainly used decision tree-based machine learning algorithms, such as random forest (RF), extreme gradient boosting trees (XGBoost), and light gradient boosting method (LightGBM). Read More

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http://dx.doi.org/10.1186/s12894-020-00662-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333255PMC

Systemic therapy for advanced clear cell renal cell carcinoma after discontinuation of immune-oncology and VEGF targeted therapy combinations.

BMC Urol 2020 Jul 2;20(1):84. Epub 2020 Jul 2.

Department of Medicine, Memorial Sloan Kettering Cancer Center (MSKCC), 300 East 66th Street, New York, NY, 10065, USA.

Background: Several phase 3 studies reported positive results for combinations of Immune-Oncology (IO) and Vascular Endothelial Growth Factor (VEGF) targeted therapies in patients with metastatic clear cell Renal Cell Carcinoma (ccRCC). However, there are limited data on outcomes to systemic therapy after IO-VEGF combinations.

Methods: A retrospective analysis was performed on patients with metastatic ccRCC treated at the Memorial Sloan Kettering Cancer Center and Cleveland Clinic who initiated systemic therapy post IO-VEGF including combinations with VEGF receptor (VEGFR) tyrosine kinase inhibitors (IO-TKI) and combinations with the anti-VEGF monoclonal antibody bevacizumab (IO-Bev). Read More

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http://dx.doi.org/10.1186/s12894-020-00647-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331268PMC

Small renal masses in Latin-American population: characteristics and prognostic factors for survival, recurrence and metastasis - a multi-institutional study from LARCG database.

BMC Urol 2020 Jul 2;20(1):85. Epub 2020 Jul 2.

A.C. Camargo Cancer Center, Rua Antônio Prudente 211, Liberdade, São Paulo, 01509-010, Brazil.

Background: To evaluate demographic, clinical and pathological characteristics of small renal masses (SRM) (≤ 4 cm) in a Latin-American population provided by LARCG (Latin-American Renal Cancer Group) and analyze predictors of survival, recurrence and metastasis.

Methods: A multi-institutional retrospective cohort study of 1523 patients submitted to surgical treatment for non-metastatic SRM from 1979 to 2016. Comparisons between radical (RN) or partial nephrectomy (PN) and young or elderly patients were performed. Read More

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http://dx.doi.org/10.1186/s12894-020-00649-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331283PMC

The Pros and cons of balloon dilation in totally ultrasound-guided percutaneous Nephrolithotomy.

BMC Urol 2020 Jul 1;20(1):82. Epub 2020 Jul 1.

Urology Department, Sheng Jing Hospital of China Medical University, Shenyang, 110000, China.

Background: To evaluate the feasibility and safety of balloon dilation (BD) in totally ultrasound-guided percutaneous nephrolithotomy (PCNL).

Methods: The data of 95 patients underwent BD were collected in this retrospective study between August 2016 and December 2018. During the same period, telescopic metal dilation was used in 1161 patients. Read More

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http://dx.doi.org/10.1186/s12894-020-00654-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329447PMC

A rare case of herniated duplex collecting system causing obstructive uropathy.

BMC Urol 2020 Jul 1;20(1):83. Epub 2020 Jul 1.

Department of Medicine, St. Elizabeth's Medical Center, Boston, MA, USA.

Background: An inguinal hernia is the protrusion of intraabdominal organs through an opening in the abdominal wall. Structures such as small and large intestines are commonly contained within inguinal hernias. However, uretero-inguinal hernia of the native collecting system is an extremely rarely reported entity. Read More

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http://dx.doi.org/10.1186/s12894-020-00652-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329524PMC

Peri-operative, functional and early oncologic outcomes of salvage robotic-assisted radical prostatectomy after high-intensity focused ultrasound partial ablation.

BMC Urol 2020 Jul 1;20(1):81. Epub 2020 Jul 1.

Department of Uro-oncology, University College London Hospital, London, W1G 8PH, UK.

Background: Partial ablation of the prostate using high-intensity focussed ultrasound (HIFU-PA) is a treatment option for localised prostate cancer. When local recurrence occurs, salvage robot-assisted radical prostatectomy is a treatment option for selected patients, but there is a paucity of data on the peri-operative safety, functional and oncologic outcomes of sRARP.. Read More

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http://dx.doi.org/10.1186/s12894-020-00656-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329479PMC

Myxoma of the renal pelvis masquerading pelviureteric stenosis: conservative limited resection with renal preservation: case presentation and literature review.

BMC Urol 2020 Jun 30;20(1):80. Epub 2020 Jun 30.

Department of Pathology, Microbiology and Forensic Medicine, School of Medicine, University of Jordan, Amman, Jordan.

Background: Myxoma is a relatively rare mesenchymal tumor seen mainly in the heart and skin. Renal myxomas in particular are exceptionally rare where only 17 cases were previously reported in the English Language literature. Only 2 of the 17 reported cases were located in the renal sinus/pelvis. Read More

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http://dx.doi.org/10.1186/s12894-020-00657-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324961PMC

Superselective embolization for high-flow priapism refractory to medical and surgical treatments.

BMC Urol 2020 Jun 30;20(1):79. Epub 2020 Jun 30.

Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, No.1, East Jian She Road, Zhengzhou, 450052, China.

Background: This study aimed to report long-term outcome of superselective embolization in patients with high-flow priapism refractory to medical and surgical treatments.

Methods: From August 2011 until July 2016, 14 patients with high-flow priapism refractory to local treatments were treated and their charts were retrospective reviewed. Clinical evaluation, color Doppler ultrasonography, arteriography and selective embolization were performed. Read More

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http://dx.doi.org/10.1186/s12894-020-00653-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325169PMC

Systemic inflammatory response syndrome in patients with acute obstructive upper tract urinary stone: a risk factor for urgent renal drainage and revisit to the emergency department.

BMC Urol 2020 Jun 29;20(1):77. Epub 2020 Jun 29.

Division of Urology Surgery, Washington University School of Medicine, 4960, Children's place, Campus Box 8242, St. Louis, MO, 63110, USA.

Background: In patients seen in the emergency department (ED) with acute stone obstruction many risk factors that indicate need for urgent renal drainage are known. However, in patients discharged from ED without renal drainage factors that can minimize revisit to the emergency department are not fully identified. We evaluated SIRS (systemic inflammatory response syndrome) as a risk factor for urgent renal drainage and revisit to the ED in patients with acute stone colic during their ED visit. Read More

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http://dx.doi.org/10.1186/s12894-020-00644-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325089PMC

Clinical characteristics and endoscopic treatment of hematospermia with postcoital hematuria.

BMC Urol 2020 Jun 29;20(1):78. Epub 2020 Jun 29.

Department of Urology, Daping Hospital, Army Medical University, No.10, Daping Changjiangzhilu, Yuzhong District, Chongqing, 400042, China.

Background: Recurrent hematospermia accompanied by postejaculatory hematuria is a very rare phenomenon, has not been well understood in the clinical setting, and usually leads to misdiagnosis and mistreatment. The aim of this study was to summarize the clinical characteristics, etiologic diagnosis, and endoscopic treatment of hematospermia with postcoital hematuria.

Methods: We collected the clinical data from 39 patients of hematospermia with postcoital hematuria, who were admitted to our hospital from May 2014 to October 2019. Read More

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http://dx.doi.org/10.1186/s12894-020-00646-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325095PMC

A case report of primary upper urinary tract signet-ring cell carcinoma and literature review.

BMC Urol 2020 Jun 26;20(1):75. Epub 2020 Jun 26.

Department of Urology, Dongguan People's Hospital, Dongguan, 523000, China.

Background: Upper tract urothelial carcinoma with pure non-urothelial histology is an exception but variants are present in ~ 25% of cases. Primary upper urinary tract signet -ring cell carcinoma is extremely rare.

Case Presentation: We report the case of a 65-year-old male diagnosed primary upper urinary tract signet-ring cell carcinoma while underwent percutaneous nephrolithotomy. Read More

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http://dx.doi.org/10.1186/s12894-020-00645-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318531PMC

Guideline-adherence in the treatment of symptomatic urolithiasis in children and adolescents in southwestern Germany.

BMC Urol 2020 Jun 26;20(1):76. Epub 2020 Jun 26.

Department of Urology and Paediatric Urology, Medical University Ulm, Albert-Einstein-Allee 23, 89081, Ulm, Germany.

Background: Approximately 1% of urolithiasis cases in Germany affect children. Interdisciplinary groups have agreed on national and international guidelines for children to recommend appropriate treatment pathways. The aim of this retrospective and preliminary study is to analyze whether adherence to current guidelines for pediatric stone disease in southwestern Germany is feasible. Read More

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http://dx.doi.org/10.1186/s12894-020-00643-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320579PMC

Renal pelvis and ureteropelvic junction incarceration in a Grynfeltt-Lesshaft hernia: a case report and review of the literature.

BMC Urol 2020 Jun 25;20(1):74. Epub 2020 Jun 25.

Department of General Surgery, Shahid Beheshti Hospital, Yasuj University of Medical Sciences, Yasuj, Iran.

Background: Grynfeltt-Lesshaft hernia is a kind of lumbar abdominal wall hernia in which clinical presentations may vary from an asymptomatic bulge in the lumbar area to a symptomatic lumbar mass with back pain. It has been accepted to be a rare entity, and incarceration of the kidney through this hernia is shown to be very rare, and very few previous cases have been reported in this regard. We present a case of renal pelvic and ureteropelvic junction incarceration in a Grynfeltt-Lesshaft hernia and provide an overview of the existing literature on it. Read More

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http://dx.doi.org/10.1186/s12894-020-00626-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318462PMC

Physician preferences for non-metastatic castration-resistant prostate cancer treatment.

BMC Urol 2020 Jun 22;20(1):73. Epub 2020 Jun 22.

Bayer U.S. LLC, Whippany, NJ, USA.

Background: Recent approvals of second-generation androgen receptor inhibitors (SGARIs) have changed the treatment landscape for non-metastatic castration-resistant prostate cancer (nmCRPC). These SGARIs have similar efficacy but differ in safety profiles. We used a discrete choice experiment to explore how United States physicians make treatment decisions between adverse events (AEs) and survival gains in nmCRPC, a largely asymptomatic disease. Read More

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http://dx.doi.org/10.1186/s12894-020-00631-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310549PMC

Expression of epithelial-Mesenchymal transition related markers in Plasmacytoid Urothelial carcinoma of the urinary bladder.

BMC Urol 2020 Jun 22;20(1):72. Epub 2020 Jun 22.

Department of Urology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan.

Background: Plasmacytoid urothelial carcinoma (PUC) of the urinary bladder is a variant of urothelial carcinoma that carries a poor prognosis. The epithelial-mesenchymal transition (EMT) has been demonstrated to contribute to tumor progression. As the cause of the increased aggressiveness of PUC is unknown, we investigated PUC and EMT-related marker expression. Read More

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http://dx.doi.org/10.1186/s12894-020-00641-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309983PMC
June 2020
1.937 Impact Factor

Early upregulation of AR and steroidogenesis enzyme expression after 3 months of androgen-deprivation therapy.

BMC Urol 2020 Jun 19;20(1):71. Epub 2020 Jun 19.

Department of Urology, CiptoMangunkusumo Hospital - Faculty of Medicine Universitas Indonesia, Jl. Diponegoro No.71, RW.5, Kenari, Senen, RW.5, Kenari, Senen, Kota Jakarta Pusat, Daerah Khusus Ibukota Jakarta, 10430, Indonesia.

Background: Androgen deprivation therapy (ADT) is a standard treatment for advanced prostate cancer (PCa). However, PCa recurrence and progression rates during ADT are high. Until now, there has been no evidence regarding when progression begins. Read More

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http://dx.doi.org/10.1186/s12894-020-00627-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304221PMC

PCNL in COPD patient in the sit position under local infiltration anesthesia case report.

BMC Urol 2020 Jun 17;20(1):70. Epub 2020 Jun 17.

Department of Urology, Beijing Jishuitan Hospital, No68.Huinanbei Road, Changping District, Beijing, 100096, China.

Background: Percutaneous nephrolithotomy is traditionally performed in the prone or supine position. We report the first case of percutaneous nephrolithotomy in sit position under local infiltration anesthesia. A 69-year-old male presented with left flank pain. Read More

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http://dx.doi.org/10.1186/s12894-020-00640-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301984PMC

Thermal effect of holmium laser during ureteroscopic lithotripsy.

BMC Urol 2020 Jun 15;20(1):69. Epub 2020 Jun 15.

Department of Urology, Xinchang County Hospital of Traditional Chinese Medicine, Shaoxing, Zhejiang Province, China.

Background: Holmium laser lithotripsy is the most common technique for the management of ureteral stone. Studies founded that holmium laser firing can produce heat which will cause thermal injury towards ureter. The aim of our current study is to explore factors affecting thermal effect of holmium laser during ureteroscopic lithotripsy. Read More

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http://dx.doi.org/10.1186/s12894-020-00639-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296665PMC
June 2020
1.937 Impact Factor

Endoscopic treatments prior to urethroplasty: trends in management of urethral stricture disease.

BMC Urol 2020 Jun 13;20(1):68. Epub 2020 Jun 13.

Department of Urology, Lahey Hospital and Medical Center, 41 Mall Rd, Burlington, MA, 01805, USA.

Background: To determine if the number of endoscopic treatments of urethral stricture disease (USD) prior to urethroplasty has changed in the context of new AUA guidelines on management of USD. In addition to an increase in practicing reconstructive urologists and published reconstructive literature, the AUA guidelines regarding the management of male USD were presented in May 2016, advocating consideration of urethroplasty in patients with 1 prior failed endoscopic treatment.

Methods: A retrospective review of a prospectively maintained, multi-institutional urethral stricture database of high volume, geographically diverse institutions was performed from 2006 to 2017. Read More

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http://dx.doi.org/10.1186/s12894-020-00638-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293125PMC

A comparison among PCNL, Miniperc and Ultraminiperc for lower calyceal stones between 1 and 2 cm: a prospective, comparative, multicenter and randomised study.

BMC Urol 2020 Jun 10;20(1):67. Epub 2020 Jun 10.

Department of Urology, ASST Valle Olona Busto Arsizio, Varese, Italy.

Background: Conventional Percutaneous Lithotripsy (PCNL) has been an effective, successful and easy approach for especially > 1 cm sized calyceal stones however risks of complications and nephron loss are inevitable. Our aim is to compare the efficacy and safety of PCNL, MiniPerc (MP) and UltraMiniPerc (UMP) for lower calyceal stones between 1 and 2 cm with a multicenter prospective randomized study.

Methods: Between January 2015 and June 2018, 132 consecutive patients with single lower calyceal stone were enrolled. Read More

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http://dx.doi.org/10.1186/s12894-020-00636-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288549PMC

Retrospective comparison of three minimally invasive approaches for adrenal tumors: perioperative outcomes of transperitoneal laparoscopic, retroperitoneal laparoscopic and robot-assisted laparoscopic adrenalectomy.

BMC Urol 2020 Jun 9;20(1):66. Epub 2020 Jun 9.

Department of Urology, Drum Tower Hospital, Medical School of Nanjing University, Institute of Urology, Nanjing University, 321 Zhongshan Rd, Nanjing, 210008, Jiangsu, People's Republic of China.

Background: To compare the perioperative outcomes of transperitoneal laparoscopic (TLA), retroperitoneal laparoscopic (RLA), and robot-assisted transperitoneal laparoscopic (RATLA) adrenalectomy for adrenal tumors in our center.

Methods: Between April 2012 and February 2018, 241 minimally invasive adrenalectomies were performed. Cases were categorized based on the minimally invasive adrenalectomy technique. Read More

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http://dx.doi.org/10.1186/s12894-020-00637-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285739PMC

Reduction of ureteral stent encrustation by modulating the urine pH and inhibiting the crystal film with a new oral composition: a multicenter, placebo controlled, double blind, randomized clinical trial.

BMC Urol 2020 Jun 5;20(1):65. Epub 2020 Jun 5.

Devicare S.L., Cerdanyola del Vallès, Spain.

Background: Encrustation of ureteral double J stents is a common complication that may affect its removal. The aim of the proposed study is to evaluate the efficacy and safety of a new oral composition to prevent double J stent encrustation in indwelling times up to 8 weeks.

Methods: A double-blinded, multicenter, placebo-controlled trial was conducted with 105 patients with indwelling double J stents enrolled across 9 public hospitals in Spain. Read More

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http://dx.doi.org/10.1186/s12894-020-00633-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275439PMC

Atypical focal xanthogranulomatous pyelonephritis without clinical symptoms presenting as infiltrative renal cancer: a case report and literature review.

BMC Urol 2020 Jun 3;20(1):63. Epub 2020 Jun 3.

Department of Urology, First Hospital of Jilin University, Changchun, Jilin, 130021, P.R. China.

Background: Xanthogranulomatous pyelonephritis (XGP) is an uncommon form of chronic pyelonephritis. Most patients of XGP are diffuse in radiology and the clinical features are typical.

Case Presentation: We present a case of 24-year-old female with the absence of symptoms and normal laboratory examinations. Read More

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http://dx.doi.org/10.1186/s12894-020-00632-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268720PMC

Unmet needs in sexual health in bladder cancer patients: a systematic review of the evidence.

BMC Urol 2020 Jun 3;20(1):64. Epub 2020 Jun 3.

King's College London, School of Cancer and Pharmaceutical Studies, Translational Oncology & Urology Research (TOUR), TOUR, Guy's Hospital, 3rd Floor Bermondsey Wing, London, SE1 9RT, UK.

Background: Bladder cancer (BC) treatment can have a detrimental effect on the sexual organs of patients and yet assessment of sexual health needs has been greatly overlooked for these patients compared to those who have undergone other cancer therapies.

Methods: This review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines in July 2019. Studies were identified by conducting searches for Medline (using the PubMed interface), the Cochrane Central Register of Controlled Trials (CENTRAL) and Ovid Gateway (Embase and Ovid) using a list of defined search terms. Read More

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http://dx.doi.org/10.1186/s12894-020-00634-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268732PMC

Quality of life among patients with multiple sclerosis and voiding dysfunction: a cross-sectional study.

BMC Urol 2020 Jun 3;20(1):62. Epub 2020 Jun 3.

Isfahan Pharmaceutical Sciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Evaluating the usefulness of treatment requires a direct measurement of the health-related quality of life (QOL). Therefore, this study was carried out aiming to determine the QOL of patients with MS and voiding dysfunction.

Methods: This cross-sectional study was carried out using multi-stage random cluster sampling method on 602 patients with MS in Isfahan, Iran. Read More

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http://dx.doi.org/10.1186/s12894-020-00590-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268392PMC

The metabolic role of PFKFB4 in androgen-independent growth in vitro and PFKFB4 expression in human prostate cancer tissue.

BMC Urol 2020 Jun 1;20(1):61. Epub 2020 Jun 1.

Department of Urology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.

Background: It is well known that androgen-deprivation therapy (ADT) can inevitably drive prostate cancer (PCa) cells into a castration-resistant state. According to the "Warburg effect", the metabolism of aggressive tumor cells increases significantly. The growth of cancer cells depends on glycolysis, which may be a potential target for cancer control. Read More

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http://dx.doi.org/10.1186/s12894-020-00635-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268689PMC
June 2020
1.937 Impact Factor

Axitinib as a third or further line of treatment in renal cancer: a single institution experience.

BMC Urol 2020 Jun 2;20(1):60. Epub 2020 Jun 2.

Oncology Unit, Department of Clinical Therapeutics, Alexandra Hospital, Athens, Greece.

Background: Kidney cancer is a lethal neoplasm that affects several thousands of people every year. Renal cell carcinoma (RCC) is the most common histologic type. Recent developments in the therapeutic approach include antiangiogenic targeted approaches and Immunotherapy. Read More

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http://dx.doi.org/10.1186/s12894-020-00618-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265645PMC

Prognostic value of systemic inflammatory factors NLR, LMR, PLR and LDH in penile cancer.

BMC Urol 2020 May 27;20(1):57. Epub 2020 May 27.

Department of Urology, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Kunming, 650118, Yunnan, China.

Background: Penile squamous cell carcinoma (PSCC) represents an important public health problem for developing countries. The major prognostic factors in PSCC are pathological subtype, perineural invasion, lymphovascular invasion, depth of invasion and grade, which are hard to obtain precisely before the operation. Besides, micro-metastases will be detected in about 30% of intermediate-risk patients with clinically non-palpable inguinal lymph nodes after inguinal lymph node dissection (ILND). Read More

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http://dx.doi.org/10.1186/s12894-020-00628-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251912PMC
May 2020
1.937 Impact Factor

A prospective observational cohort study of posterior tibial nerve stimulation in patients with multiple sclerosis: design and methods.

BMC Urol 2020 May 27;20(1):58. Epub 2020 May 27.

Department of Urology, University of Michigan, 1500 East Medical Drive, Taubman Center 3875, Ann Arbor, MI, 48109, USA.

Background: Posterior tibial nerve stimulation (PTNS) is a promising treatment for lower urinary tract symptoms (LUTS) in patients with MS. However, long term data focusing on PTNS impact on health-related quality of life (HRQOL), bowel and bladder symptoms are lacking. This paper describes a study protocol that examines the extended efficacy of PTNS on MS related bladder and bowel symptoms and resulting HRQOL. Read More

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http://dx.doi.org/10.1186/s12894-020-00629-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251681PMC

Risk assessment of neuromuscular stimulation by energy-based transurethral resection devices: an ex vivo test standard.

BMC Urol 2020 May 27;20(1):59. Epub 2020 May 27.

Department of Urology, University Hospital Tuebingen, Tuebingen, Germany.

Background: During transurethral resection of bladder tumours (TURB), radio-frequency (RF) currents can lead to adverse neuromuscular stimulation (NMS). Here we present a novel ex vivo method to determine the risk of RF generators and their bipolar TURB modes to cause NMS. We aimed to develop an experimental platform for safety evaluation of new RF generators and their modes with a newly established test standard, suitable for replacement or reduction of animal testing. Read More

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http://dx.doi.org/10.1186/s12894-020-00630-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254752PMC

LithoVue™ for renal stone therapy - a perfect fit for high volume academic centers; a retrospective evaluation of 108 cases.

BMC Urol 2020 May 18;20(1):56. Epub 2020 May 18.

Landeskrankenhaus Salzburg - Universitätsklinikum der Paracelsus Medizinischen Privatuniversität, Universitätsklinik für Urologie und Andrologie, Müllner Hauptstraße 48, 5020, Salzburg, Austria.

Background: Over the last few years the number of flexible ureterorenoscopies, used for renal stone treatment, has risen steadily. This was associated with an increase in costs for maintenance and repair of the fragile ureterorenoscopes used. To overcome this problem single-use devices have been introduced to the market. Read More

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http://dx.doi.org/10.1186/s12894-020-00624-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236187PMC

Does age alone negatively predict the outcome of sacral neuromodulation? A single-centre retrospective observational study.

BMC Urol 2020 May 14;20(1):55. Epub 2020 May 14.

Department of Urology and Kidney Transplantation, Martin Luther University, Ernst-Grube-Straße 40, 06120, Halle (Saale), Germany.

Background: For patients over the age of 70 years, sacral neuromodulation (SNM) is often not considered a potential therapeutic option. We therefore report on our results from performing SNM in elderly patients ≥70 years.

Methods: Between 01/09 and 12/18, a total of 95 patients with refractory overactive bladder (OAB) or chronic non-obstructive urinary retention underwent SNM testing at our department. Read More

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http://dx.doi.org/10.1186/s12894-020-00621-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227205PMC

Kidney triplication with ectopic ureterocele: a case report.

BMC Urol 2020 May 13;20(1):54. Epub 2020 May 13.

Urology Department, State Pediatric Medical University, 2 Litovskaya Street, build.2, St. Petersburg, Russian Federation, 194100.

Background: Kidney triplication is a rare urological abnormality. Association of triplex kidney and ureterocele is out of ordinary. Treatment of such patients usually implies heminephrureterectomy of the upper moiety. Read More

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http://dx.doi.org/10.1186/s12894-020-00625-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222539PMC

Serum omentin-1 level in patients with benign prostatic hyperplasia.

BMC Urol 2020 May 6;20(1):52. Epub 2020 May 6.

Department of Urology, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China.

Backgroud: To evaluate the relationship between omentin-1 and benign prostatic hyperplasia (BPH). BPH is the most common urological disease in elderly men worldwide. Lower serum omentin-1 levels were reported to be negatively associated with the incidence of inflammation, diabetes, obesity and metabolic syndrome, which all play a role in the development of BPH. Read More

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http://dx.doi.org/10.1186/s12894-020-00623-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203873PMC

Contasure-needleless single incision slings versus transobturator slings (TOT/TVT-O) for female patients with stress urinary incontinence: a systematic review and meta-analysis.

BMC Urol 2020 May 6;20(1):51. Epub 2020 May 6.

Peking University China-Japan Friendship School of Clinical Medicine, Beijing, China.

Background: To assess the current evidence on the effectiveness and safety of Contasure-Needleless (C-NDL) versus transobturator slings (TOT/TVT-O) in the management of female stress urinary incontinence (SUI).

Methods: A comprehensive literature review of articles that investigated the efficacy and safety of C-NDL and TOT/TVT-O was performed based on studies published before June 2019 and retrieved from PubMed, Embase, CNKI and the Cochrane Library. Two reviewers searched the literature, independently extracted the data and evaluated the quality of the data according to the inclusion and exclusion criteria. Read More

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http://dx.doi.org/10.1186/s12894-020-00622-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204064PMC

Preoperative positive urine nitrite and albumin-globulin ratio are independent risk factors for predicting postoperative fever after retrograde Intrarenal surgery based on a retrospective cohort.

BMC Urol 2020 May 6;20(1):50. Epub 2020 May 6.

Department of Urology, Institute of Urology (Laboratory of Reconstructive Urology), West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu, Sichuan, 610041, P.R. China.

Background: To determine risk factors for postoperative fever (POF) after retrograding intrarenal surgery (RIRS) and a nomogram for prediction of POF in patients undertaking RIRS has been developed based on the risk factors found.

Methods: This is a retrospective designed-study. A continuous cohort from a single-center database that consisted of 1095 cases undertaking RIRS with complete preoperative medical records from January 2009 to December 2018 was obtained. Read More

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http://dx.doi.org/10.1186/s12894-020-00620-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201725PMC

Burkitt's lymphoma of the prostate presenting as acute urinary retention: a case report.

BMC Urol 2020 May 6;20(1):53. Epub 2020 May 6.

Department of Urology and Pediatric Urology, University Hospital, Philipps-University Marburg, Baldingerstr. 1, 35043, Marburg, Germany.

Background: Non-Hodgkin lymphomas, which include Burkitt's lymphoma, affect the prostate in only 0.1% of cases. They most commonly present as painless lymphadenopathy elsewhere in the body and can cause abdominal or thoracic pain and systemic symptoms such as fever, weight loss and night sweats. Read More

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http://dx.doi.org/10.1186/s12894-020-00616-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203870PMC

miR-185 inhibits prostate cancer angiogenesis induced by the nodal/ALK4 pathway.

BMC Urol 2020 May 4;20(1):49. Epub 2020 May 4.

Department of Urology, Jingzhou Central Hospital and The Second Clinical Medical College, Yangtze University, No.60 Jingzhong Road, Jingzhou District, Jingzhou, 434020, Hubei Province, People's Republic of China.

Background: Inhibition of angiogenesis in prostatic cancer could be a brand-new method to suppress tumour progression. Nodal/ALK4 has been associated with vascularization in many cancers. However, the relationship between and role of Nodal/ALK4 and miR-185 in human prostatic cancer is still unknown. Read More

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http://dx.doi.org/10.1186/s12894-020-00617-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197131PMC