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    732 results match your criteria BMC Urology[Journal]

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    Characterizing the transcutaneous electrical recruitment of lower leg afferents in healthy adults: implications for non-invasive treatment of overactive bladder.
    BMC Urol 2018 Feb 13;18(1):10. Epub 2018 Feb 13.
    Institute of Biomaterials and Biomedical Engineering, University of Toronto, 164 College Street, Room 407, Toronto, ON, M5S 3G9, Canada.
    Background: As a potential new treatment for overactive bladder (OAB), we investigated the feasibility of non-invasively activating multiple nerve targets in the lower leg.

    Methods: In healthy participants, surface electrical stimulation (frequency = 20 Hz, pulse width = 200 μs) was used to target the tibial nerve, saphenous nerve, medial plantar nerve, and lateral plantar nerve. At each location, the stimulation amplitude was increased to define the thresholds for evoking (1) cutaneous sensation, (2) target nerve recruitment and (3) maximum tolerance. Read More

    Scrotal hemorrhage after testicular sperm aspiration may be associated with phosphodiesterase-5 inhibitor administration: a retrospective study.
    BMC Urol 2018 Feb 6;18(1). Epub 2018 Feb 6.
    Department of Neurology, Integrated Hospital of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.
    Background: Scrotal hemorrhage after testicular sperm aspiration (TESA) is uncommon in clinical operation. Phosphodiesterase-5 inhibitors (PDE5i) are commonly given to men who have difficulty providing a sperm sample for assisted reproductive technique such as in vitro fertilization. In this study, we examine the incidence of scrotal hemorrhage after TESA in men who received a PDE5i. Read More

    Unilateral pedal lymphangiography plus computed tomography angiography for location of persistent idiopathic chyle leakage not detectable by ordinary contrast computed tomography.
    BMC Urol 2018 Feb 6;18(1). Epub 2018 Feb 6.
    Department of Urology, Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, 197 Ruijin Er Road, Shanghai, 200025, People's Republic of China.
    Background: To identify the value of unilateral pedal lymphangiography (LPG) plus computed tomography angiography (CTA) in accurate depiction of persistent idiopathic chyluria undetectable by ordinary contrast CT.

    Methods: Eighteen patients 44-63 years of age with persistent idiopathic chyluria who failed conservative management were included. Ordinary CT had not revealed a chyle leak. Read More

    Level of invasion into fibromuscular band is an independent factor for positive surgical margin and biochemical recurrence in men with organ confined prostate cancer.
    BMC Urol 2018 Feb 2;18(1). Epub 2018 Feb 2.
    Department of Urology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-Ro 43 Gil Songpa-Gu, Seoul, 05505, Republic of Korea.
    Background: This study aimed investigate the effect of the level of invasion into fibromuscular band (FMB) of prostate on the positive surgical margin (PSM) and biochemical recurrence (BCR) after radical prostatectomy (RP) in patients with organ-confined (pT2) prostate cancer.

    Methods: The clinical and pathological data of 461 consecutive patients with pT2 prostate cancer were evaluated regarding the level of invasion into FMB. The relationship between levels of invasion into FMB and PSM / BCR was assessed. Read More

    Intravescical prostatic protrusion is a predictor of alpha blockers response: results from an observational study.
    BMC Urol 2018 Feb 2;18(1). Epub 2018 Feb 2.
    Department of Experimental Medicine and Surgery, University "Tor Vergata", Rome, Italy.
    Background: To investigate the efficacy of tamsulosin in patients with lower urinary tract symptoms (LUTS) and benign prostatic enlargement (BPE) with intravesical prostatic protrusion (IPP). Ultrasound measurement of the IPP has been previously described as an effective instrument for the evaluation of benign prostatic obstruction (BPO) and could help in clarifying the role of alpha-blockers in patients with (BPE).

    Methods: Patients with BPE and LUTS were enrolled in this observational study. Read More

    Perineural invasion as an independent predictor of biochemical recurrence in prostate cancer following radical prostatectomy or radiotherapy: a systematic review and meta-analysis.
    BMC Urol 2018 Feb 1;18(1). Epub 2018 Feb 1.
    Departments of Urology, Affiliated Jiang-yin Hospital of the Southeast University Medical College, Jiang-yin, 214400, China.
    Background: Although numerous studies have shown that perineural invasion (PNI) is linked to prostate cancer (PCa) risk, the results have been inconsistent. This study aimed to explore the association between PNI and biochemical recurrence (BCR) in patients with PCa following radical prostatectomy (RP) or radiotherapy (RT).

    Methods: According to the PRISMA statement, we searched the PubMed, EMBASE, Chinese National Knowledge Infrastructure (CNKI) and Wan Fang databases from inception to May 2017. Read More

    Metastatic renal cell carcinoma initially presenting with hematochezia and subsequently with vaginal bleeding: a case report.
    BMC Urol 2018 Jan 30;18(1). Epub 2018 Jan 30.
    Department of Surgery, Division of Urology, Université de Sherbrooke, Centre Hospitalier Universitaire de Sherbrooke (CHUS), 3001 12e avenue Nord, Sherbrooke, QC, J1H 5N4, Canada.
    Background: We report an unusual case of a synchronous rectal and metachronous vaginal metastatic renal cell carcinoma.

    Case Presentation: A 78-year-old woman presented with hematochezia and a colonoscopy revealed a metastatic clear-cell renal cell carcinoma rectal polyp biopsy-proven. Abdominal computed tomography identified a 9. Read More

    Sociodemographic correlates of urine culture test utilization in Calgary, Alberta.
    BMC Urol 2018 Jan 8;18(1). Epub 2018 Jan 8.
    Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, AB, Canada.
    Background: Many clinical practice guidelines encourage diagnosis and empiric treatment of lower urinary tract infection without laboratory investigation; however, urine culture testing remains one of the largest volume tests in the clinical microbiology laboratory. In this study, we sought to determine if there were specific patient groups to which increased testing was directed. To do so, we combined laboratory data on testing rates with Census Canada sociodemographic data. Read More

    Artificial urinary sphincter implantation: an important component of complex surgery for urinary tract reconstruction in patients with refractory urinary incontinence.
    BMC Urol 2018 Jan 8;18(1). Epub 2018 Jan 8.
    Department of Urology, China Rehabilitation Research Center, Beijing, 100068, China.
    Background: We review our outcomes and experience of artificial urinary sphincter implantation for patients with refractory urinary incontinence from different causes.

    Methods: Between April 2002 and May 2017, a total of 32 patients (median age, 40.8 years) with urinary incontinence had undergone artificial urinary sphincter placement during urinary tract reconstruction. Read More

    Suprapubic tube versus urethral catheter drainage after robot-assisted radical prostatectomy: a systematic review and meta-analysis.
    BMC Urol 2018 Jan 5;18(1). Epub 2018 Jan 5.
    Department of Urology, Institute of Urology (Laboratory of Reconstructive Urology), West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu, Sichuan, 610041, People's Republic of China.
    Background: Prostate cancer is one of the most common cancers in the elderly population. The standard treatment is radical prostatectomy (RARP). However, urologists do not have consents on the postoperative urine drainage management (suprapubic tube (ST)/ urethral catheter (UC)). Read More

    Expression of cannabinoid 1 and, 2 receptors and the effects of cannabinoid 1 and, 2 receptor agonists on detrusor overactivity associated with bladder outlet obstruction in rats.
    BMC Urol 2017 Dec 29;17(1):121. Epub 2017 Dec 29.
    Department of Urology, Bucheon St. Mary's hospital, College of Medicine, The Catholic University of Korea, Sosa-Ro 327, Wonmi-gu, Bucheon-si, Gyeonggi-do, Seoul, 14647, South Korea.
    Background: This study investigated changes in the expression of cannabinoid (CB) receptors and the effects of CB1 and CB2 agonists on detrusor overactivity (DO) associated with bladder outlet obstruction (BOO) in rats.

    Methods: Male Sprague Dawley rats were randomly assigned to four groups (n = 10) in each group. The control group comprised sham-operated rats. Read More

    Combined bladder neck preservation and posterior musculofascial reconstruction during robotic assisted radical prostatectomy: effects on early and long term urinary continence recovery.
    BMC Urol 2017 Dec 15;17(1):119. Epub 2017 Dec 15.
    Urology Unit University of Pisa, Pisa, Italy.
    Background: To evaluate the effects of combined bladder neck preservation and posterior reconstruction techniques on early and long term urinary continence in patients treated by robotic assisted radical prostatectomy (RARP).

    Methods: Two-hundred ninety-two patients who previously underwent radical prostatectomy were retrospectively selected for a case-control study, excluding those with anastomotic strictures and significant perioperative complications and re-called for a medical follow-up visit after their consent to participate the study. They were divided in 3 different groups according to the surgical technique previously received: radical retropubic prostatectomy (RRP) combined with bladder neck preservation (BNP), RARP with bladder neck resection, and RARP combined with BNP and posterior musculofascial reconstruction (PRec). Read More

    A prospective study of magnetic resonance imaging and ultrasonography (MRI/US)-fusion targeted biopsy and concurrent systematic transperineal biopsy with the average of 18-cores to detect clinically significant prostate cancer.
    BMC Urol 2017 Dec 12;17(1):117. Epub 2017 Dec 12.
    Department of Urology, The University of Tokyo Graduate School of Medicine, Tokyo, Japan.
    Background: This study compared the detection rates for clinically significant prostate cancer (CSPC) between magnetic resonance imaging and ultrasonography (MRI/US)-fusion-targeted biopsy (TB), systematic biopsy (SB) and combination of TB and SB.

    Methods: This prospective study evaluated simultaneous TB and SB for consecutive patients with suspicious lesions that were detected using pre-biopsy multiparametric MRI. A commercially available real-time virtual sonography system was used to perform the MRI/US-fusion TB with the transperineal technique. Read More

    Evaluation of serum prolidase activity and oxidative stress markers in men with BPH and prostate cancer.
    BMC Urol 2017 Dec 12;17(1):116. Epub 2017 Dec 12.
    Department of Urology, Sutcu Imam University, Avsar Kampusu, 46100, Kahramanmaras, Turkey.
    Background: Prostate cancer (PCa) and benign prostatic hyperplasia (BPH) are diseases of elderly men and are related to increased oxidative stress (OS). Although prolidase has a role in collagen metabolism, it is also used to evaluate OS in many diseases. However, there is a lack of data about serum prolidase activity (SPA) in prostate cancer. Read More

    Risks and complications of transurethral resection of bladder tumors in patients receiving antiplatelet and/or anticoagulant therapy: a retrospective cohort study.
    BMC Urol 2017 Dec 12;17(1):118. Epub 2017 Dec 12.
    Department of Urology, Jichi Medical University Saitama Medical Center, 1-847 Amanuma-cho, Omiya-ku, Saitama, 330-8503, Japan.
    Background: Information on the safety of transurethral resection of bladder tumors (TURBT) in patients receiving anti-thromboembolic drugs is currently lacking. This study aimed to evaluate the clinical safety of TURBT in patients receiving anti-thromboembolic agents compared with patients not taking these agents and patients who interrupted their use perioperatively.

    Methods: We retrospectively analyzed data for patients who underwent TURBT at Jichi Medical University Saitama Medical Center from September 2013 to August 2016. Read More

    Increased expression of neuregulin 1 in the urothelium of rat bladder with partial bladder outlet obstruction.
    BMC Urol 2017 Dec 8;17(1):115. Epub 2017 Dec 8.
    Department of Urology, School of Medicine, Chungnam National University Hospital, Chungnam National University, 282 Monwha-ro, Jung-gu, Daejeon, Republic of Korea, 35015.
    Background: This study determined whether changes in the expression of neuregulin (NRG) 1, erbB2 tyrosine kinase (ErbB2) and the M2 muscarinic receptor in the urothelium and detrusor muscle of the rat bladder were associated with partial bladder outlet obstruction (PBOO).

    Methods: Male Sprague-Dawley rats (body weight 250-300 g) were used and subdivided into control (n = 10) and PBOO groups (n = 20). PBOO was induced for 21 days, and the expression of NRG1, ErbB2 and M2 muscarinic receptor mRNA and protein was evaluated using reverse transcriptase-polymerase chain reaction (RT-PCR) and western blotting, respectively. Read More

    Emerging concepts and spectrum of renal injury following Intravesical BCG for non-muscle invasive bladder cancer.
    BMC Urol 2017 Dec 6;17(1):114. Epub 2017 Dec 6.
    Royal Shrewsbury Hospital, Mytton Oak Road, Shrewsbury, SY3 8XQ, UK.
    Background: Intravesical Bacilli Calmette-Guerin (IVBCG) therapy for non-muscle invasive bladder cancer (NMIBC) has long been in use successfully. Albeit rarely, we still face with its safety concerns more than 25 years on since its approval by US Food and Drug Agency in 1990. Local and systemic infection following intravesical BCG is widely reported as compared to immune mediated local or systemic hypersensitivity reactions involving kidneys; acute kidney injury (AKI) and other renal manifestations are well reported but not of chronic kidney disease (CKD). Read More

    Expression of micro-RNAs and genes related to angiogenesis in ccRCC and associations with tumor characteristics.
    BMC Urol 2017 Dec 4;17(1):113. Epub 2017 Dec 4.
    Laboratory of Medical Investigation (LIM55), Urology Department, University of Sao Paulo Medical School, Av. Dr. Arnaldo 455, 2° floor, room 2145, Sao Paulo, 01246-903, Brazil.
    Background: Clear cell renal cell carcinoma (ccRCC) is the third most common urological cancer in adults. Our aim is to evaluate genes and miRNAs expression profiles involved with angiogenesis and tumor characteristics in ccRCC.

    Methods: The expression levels of miRNAs miR-99a, 99b, 100; 199a; 106a; 106b; 29a; 29b; 29c; 126; 200a, 200b and their respective target genes: mTOR, HIF1-α, VHL, PDGF, VEGF, VEGFR1 and VEGFR2 were analyzed using qRT-PCR in tumor tissue samples from 56 patients with ccRCC. Read More

    Involvement of the bone morphogenic protein/SMAD signaling pathway in the etiology of congenital anomalies of the kidney and urinary tract accompanied by cryptorchidism.
    BMC Urol 2017 Dec 2;17(1):112. Epub 2017 Dec 2.
    Department of Pediatric urology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Japan.
    Background: Congenital anomalies of the kidney and urinary tract (CAKUT), such as renal dysplasia, hydronephrosis, or vesicoureteral reflux, are the most common causes of end-stage renal disease. However, the genetic etiology of CAKUT remains unclear. In this study, we performed whole exome sequencing (WES) to elucidate the genetic etiology of symptomatic CAKUT and CAKUT accompanied by cryptorchidism. Read More

    Psychometric properties of the expanded prostate cancer index composite - 26 instrument in a cohort of radical prostatectomy patients: theoretical and practical examinations.
    BMC Urol 2017 Dec 2;17(1):111. Epub 2017 Dec 2.
    National Resource Center for Late Effects after Cancer Treatment, Oslo University Hospital, The Norwegian Radium Hospital, P.O. Box 4453, Nydalen, 0424, Oslo, Norway.
    Background: Recently, the Expanded Prostate Cancer Index Composite 26-item version (EPIC-26) was recommended for the assessment of adverse effects after the treatment of prostate cancer without clear reasons. This decision encouraged us to review the questionnaire development from the UCLA Prostate Cancer Index (UCLA-PCI) to the EPIC-16 CP with a focus on psychometric properties. We also reviewed PubMed for papers concerning such properties of the EPIC-26 since 2012 (latest review in 2011). Read More

    Adjuvant chemotherapy improves survival of patients with high-risk upper urinary tract urothelial carcinoma: a propensity score-matched analysis.
    BMC Urol 2017 Dec 1;17(1):110. Epub 2017 Dec 1.
    Department of Urology, Osaka University Graduate School of Medicine, 2-2 Yamada-oka, Suita, Osaka, 565-0871, Japan.
    Background: The purposes of this study were to determine whether adjuvant chemotherapy (AC) improved the prognosis of patients with high-risk upper urinary tract urothelial carcinoma (UTUC)and to identify the patients who benefited from AC.

    Methods: Among a multi-center database of 1014 patients who underwent RNU for UTUC, 344 patients with ≥ pT3 or the presence of lymphovascular invasion (LVI) were included. Cancer-specific survival (CSS) estimates were calculated by the Kaplan-Meier method, and groups were compared by the log-rank test. Read More

    A Drosophila genetic model of nephrolithiasis: transcriptional changes in response to diet induced stone formation.
    BMC Urol 2017 Nov 28;17(1):109. Epub 2017 Nov 28.
    Oxford Stone Group, Department of Urology, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.
    Background: Urolithiasis is a significant healthcare issue but the pathophysiology of stone disease remains poorly understood. Drosophila Malpighian tubules were known to share similar physiological function to human renal tubules. We have used Drosophila as a genetic model to study the transcriptional response to stone formation secondary to dietary manipulation. Read More

    Association of lower urinary tract symptoms and OAB severity with quality of life and mental health in China, Taiwan and South Korea: results from a cross-sectional, population-based study.
    BMC Urol 2017 Nov 21;17(1):108. Epub 2017 Nov 21.
    Astellas Pharma Singapore Pte. Ltd., Singapore, Singapore.
    Background: Lower urinary tract symptoms (LUTS) and overactive bladder (OAB) symptoms have a substantial effect on quality of life (QoL). We report QoL and mental health results from a LUTS prevalence study in three Asian countries.

    Methods: A cross-sectional, population-representative, internet-based study among individuals aged ≥40 years in China, Taiwan and South Korea. Read More

    The R.I.R.S. scoring system: An innovative scoring system for predicting stone-free rate following retrograde intrarenal surgery.
    BMC Urol 2017 Nov 21;17(1):105. Epub 2017 Nov 21.
    Department of Urology, Shanghai General Hospital of Nanjing Medical University, No.100, Haining Road, Hongkou District, Shanghai, 200080, China.
    Background: To establish and internally validate an innovative R.I.R. Read More

    New steps of robot-assisted radical prostatectomy using the extraperitoneal approach: a propensity-score matched comparison between extraperitoneal and transperitoneal approach in Japanese patients.
    BMC Urol 2017 Nov 21;17(1):106. Epub 2017 Nov 21.
    Department of Nephro-urology, Nagoya City University Graduate School of Medical Sciences, 1, Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, 467-8601, Japan.
    Background: Robot-assisted radical prostatectomy (RARP) is commonly performed using the transperitoneal (TP) approach with six trocars over an 8-cm distance in the steep Trendelenburg position. In this study, we investigated the feasibility and the benefit of using the extraperitoneal (EP) approach with six trocars over a 4-cm distance in a flat or 5° Trendelenburg position. We also introduced four new steps to the surgical procedure and compared the surgical results and complications between the EP and TP approach using propensity score matching. Read More

    Necrotizing fasciitis after high-dose rate brachytherapy and external beam radiation for prostate cancer: a case report.
    BMC Urol 2017 Nov 21;17(1):107. Epub 2017 Nov 21.
    Department of Urology, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-8509, Japan.
    Background: In recent years, the delayed side effects associated with radiotherapy for prostate cancer have drawn the interest of urologists. Although urosymphyseal fistula is one of these delayed side effects, this serious complication is rarely described in literature and is poorly recognized.

    Case Presentation: We report our experience in treating a 77-year-old male patient with necrotizing fasciitis after high-dose rate brachytherapy plus external beam radiation for prostate cancer. Read More

    Clinical utility of computed tomography Hounsfield characterization for percutaneous nephrolithotomy: a cross-sectional study.
    BMC Urol 2017 Nov 16;17(1):104. Epub 2017 Nov 16.
    Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Department of Urology, University of Milan, Via della Commenda 15, 20122, Milan, Italy.
    Background: Computed Tomography (CT) is considered the gold-standard for the pre-operative evaluation of urolithiasis. However, no Hounsfield (HU) variable capable of differentiating stone types has been clearly identified. The aim of this study is to assess the predictive value of HU parameters on CT for determining stone composition and outcomes in percutaneous nephrolithotomy (PCNL). Read More

    Upper urinary tract stone disease in patients with poor performance status: active stone removal or conservative management?
    BMC Urol 2017 Nov 16;17(1):103. Epub 2017 Nov 16.
    Department of Urology, Wakayama Medical University, 811-1 Kimiidera, Wakayama City, Wakayaka, 641-0012, Japan.
    Background: It remains controversial as to whether active stone removal should be performed in patients with poor performance status because of their short life expectancy and perioperative risks. Our objectives were to evaluate treatment outcomes of active stone removal in patients with poor performance status and to compare life prognosis with those managed conservatively.

    Methods: We retrospectively reviewed 74 patients with Eastern Cooperative Oncology Group performance status 3 or 4 treated for upper urinary tract calculi at our four hospitals between January 2009 and March 2016. Read More

    Extraperitoneal laparoscopic resection for retroperitoneal lymphatic cysts: initial experience.
    BMC Urol 2017 Nov 13;17(1):101. Epub 2017 Nov 13.
    Department of Urology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China.
    Background: To assess the safety and efficacy of laparoscopic retroperitoneal resection for retroperitoneal lymphatic cysts.

    Methods: A retrospective analysis was conducted based on clinical data from eight patients with hydronephrosis caused by retroperitoneal lymphatic cysts. All patients underwent laparoscopic retroperitoneal lymphatic cyst resection and received postoperative follow-up. Read More

    Tubeless versus standard percutaneous nephrolithotomy: an update meta-analysis.
    BMC Urol 2017 Nov 13;17(1):102. Epub 2017 Nov 13.
    Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No.1095 Jiefang Avenue, Wuhan, China.
    Background: To update a previously published systematic review and meta-analysis on the efficacy and safety of tubeless percutaneous nephrolithotomy (PCNL).

    Methods: A systematic literature search of EMBASE, PubMed, Web of Science, and the Cochrane Library was performed to confirm relevant studies. The scientific literature was screened in accordance with the predetermined inclusion and exclusion criteria. Read More

    Correction to: Robot-assisted laparoscopic reconstructed management of multiple aneurysms in renal artery primary bifurcations: a case report and literature review.
    BMC Urol 2017 Nov 3;17(1):100. Epub 2017 Nov 3.
    Department of Urology, Zhejiang Provincial People's Hospital, No. 158, Shangtang Road, Xiacheng District, Hangzhou, Zhejiang, 310014, China.
    Correction: After publication of this work [1] it was noticed the author - Jie Wang's name was in the wrong order. The original article was corrected. The publisher apologises for this error. Read More

    Role of calcifying nanoparticles in the development of testicular microlithiasis in vivo.
    BMC Urol 2017 Oct 30;17(1):99. Epub 2017 Oct 30.
    Department of Obstetrics and Gynecology, Daping Hospital, Third Military Medical University, Chongqing, 400038, People's Republic of China.
    Background: Calcifying nanoparticles (NPs) have been proven to be associated with a variety of pathological calcification and previously detected in semen samples from patients with testicular microlithiasis (TM). The present study was designed to test the hypothesis if human-derived NPs could invade the seminiferous tubules and induce TM phenotype.

    Methods: The animals were divided into three groups. Read More

    Canadian Men's perspectives about active surveillance in prostate cancer: need for guidance and resources.
    BMC Urol 2017 Oct 27;17(1):98. Epub 2017 Oct 27.
    Institut du cancer de Montréal and Centre de recherche du Centre hospitalier de l'Université de Montréal, 900 St Denis St, Montreal, QC, Canada.
    Background: In prostate cancer, men diagnosed with low risk disease may be monitored through an active surveillance. This research explored the perspectives of men with prostate cancer regarding their decision-making process for active surveillance to identify factors that influence their decision and assist health professionals in having conversations about this option.

    Methods: Focus group interviews (n = 7) were held in several Canadian cities with men (N = 52) diagnosed with prostate cancer and eligible for active surveillance. Read More

    Ureteral reconstruction using a tapered non-vascularized bladder graft: an experimental study in a canine animal model.
    BMC Urol 2017 Oct 23;17(1):97. Epub 2017 Oct 23.
    Department of Urology, Huashan Hospital, Fudan University, No.12 Wulumuqi Middle Road, Shanghai, 200040, People's Republic of China.
    Background: Reconstruction of ureteral defects and strictures remains problematic for urologists. We aimed to investigate the possibility of a tapered non-vascularized bladder graft as a novel substitute for ureteral reconstruction.

    Methods: This experimental study was conducted on nine beagles. Read More

    Robot-assisted laparoscopic reconstructed management of multiple aneurysms in renal artery primary bifurcations: a case report and literature review.
    BMC Urol 2017 Oct 16;17(1):96. Epub 2017 Oct 16.
    Department of Urology, Zhejiang Provincial People's Hospital, No. 158, Shangtang Road, Xiacheng District, Hangzhou, Zhejiang, 310014, China.
    Background: Renal artery aneurysm (RAA) is rare and its incidence in the general population remains elusive. There have been few reports on the repair of multiple aneurysms conducted with the Da Vinci robot-assisted surgical platform (Intuitive Surgical Inc., Sunnyvale, CA, USA), especially for those located in renal artery primary bifurcations. Read More

    Traumatic penile amputation: a case report.
    BMC Urol 2017 Oct 10;17(1):93. Epub 2017 Oct 10.
    Department of Urology, Indira Gandhi Medical College & Hospital, Shimla, Himachal Pradesh, 171001, India.
    Background: Traumatic amputation of the penis is a rare surgical emergency. Although repair techniques have been well described in literature, failure of replantation and its causes are poorly understood and reported. Herein, we report the case of a 9 year old boy who underwent replantation of his amputated penis with delayed failure of the surgery, along with a discussion of recent advances in the management of this condition. Read More

    Acceptability of dietary and physical activity lifestyle modification for men following radiotherapy or radical prostatectomy for localised prostate cancer: a qualitative investigation.
    BMC Urol 2017 Oct 10;17(1):94. Epub 2017 Oct 10.
    University of Bristol, NIHR Biomedical Research Centre - Nutrition, Diet and Lifestyle Theme, Level 3, University Hospitals Bristol Education Centre, Upper Maudlin Street, Bristol, BS2 8AE, England, UK.
    Background: The experience and acceptability of lifestyle interventions for men with localised prostate cancer are not well understood, yet lifestyle interventions are increasingly promoted for cancer survivors. We explored the opinions, experiences and perceived acceptability of taking part in nutritional and physical activity interventions amongst men with prostate cancer and their partners; with the ultimate plan to use such information to inform the development of nutritional and physical activity interventions for men with prostate cancer.

    Methods: Semi-structured interviews with 16 men, and seven partners, undergoing curative surgery or radiotherapy for prostate cancer. Read More

    Study protocol: patient reported outcomes for bladder management strategies in spinal cord injury.
    BMC Urol 2017 Oct 10;17(1):95. Epub 2017 Oct 10.
    Division of Urology, Department of Surgery, University of Utah Health Care, 30 North 1900 East, Room #3B420, Salt Lake City, UT, 84132, USA.
    Background: The majority of spinal cord injury (SCI) patients have urinary issues, such as incontinence, retention, and frequency. These problems place a significant burden on patients' physical health and quality of life (QoL). There are a wide variety of bladder management strategies available to patients with no clear guidelines on appropriate selection. Read More

    Effects of increasing the PSA cutoff to perform additional biomarker tests before prostate biopsy.
    BMC Urol 2017 Oct 3;17(1):92. Epub 2017 Oct 3.
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, S-171 77, Stockholm, Sweden.
    Background: Multi-step testing might enhance performance of the prostate cancer diagnostic pipeline. Using PSA >1 ng/ml for first-line risk stratification and the Stockholm 3 Model (S3M) blood-test >10% risk of Gleason Score > 7 prostate cancer to inform biopsy decisions has been suggested. We aimed to determine the effects of changing the PSA cutoff to perform reflex testing with S3M and the subsequent S3M cutoff to recommend prostate biopsy while maintaining the sensitivity to detect Gleason Score ≥ 7 prostate cancer. Read More

    Positive surgical margins and biochemical recurrence following minimally-invasive radical prostatectomy - An analysis of outcomes from a UK tertiary referral centre.
    BMC Urol 2017 Oct 2;17(1):91. Epub 2017 Oct 2.
    Department of Urology, Freeman Hospital, Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle-upon-Tyne, UK.
    Background: Positive surgical margins are a strong prognostic marker of disease outcome following radical prostatectomy, though prior evidence is largely from a PSA-screened population. We therefore aim to evaluate the biochemical recurrence in men with positive surgical margins (PSM) after minimally-invasive radical prostatectomy (MIRP) in a UK tertiary centre.

    Methods: Retrospective study of men undergoing laparoscopic or robotic-assisted radical prostatectomy between 2002 and 2014. Read More

    Bacteriophages for treating urinary tract infections in patients undergoing transurethral resection of the prostate: a randomized, placebo-controlled, double-blind clinical trial.
    BMC Urol 2017 Sep 26;17(1):90. Epub 2017 Sep 26.
    Neuro-Urology, Spinal Cord Injury Center & Research, University of Zürich, Balgrist University Hospital, Zürich, Switzerland.
    Background: Urinary tract infections (UTI) are among the most prevalent microbial diseases and their financial burden on society is substantial. The continuing increase of antibiotic resistance worldwide is alarming. Thus, well-tolerated, highly effective therapeutic alternatives are urgently needed. Read More

    Design of a single-arm clinical trial of regenerative therapy by periurethral injection of adipose-derived regenerative cells for male stress urinary incontinence in Japan: the ADRESU study protocol.
    BMC Urol 2017 Sep 25;17(1):89. Epub 2017 Sep 25.
    Department of Urology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi, 466-8550, Japan.
    Background: Male stress urinary incontinence is a prevalent condition after radical prostatectomy. While the standard recommendation for the management of urine leakage is pelvic floor muscle training, its efficacy is still unsatisfactory. Therefore, we have focused on regenerative therapy, which consists of administering a periurethral injection of autologous regenerative cells from adipose tissue, separated using the Celution® system. Read More

    The validation of the Dutch SF-Qualiveen, a questionnaire on urinary-specific quality of life, in spinal cord injury patients.
    BMC Urol 2017 Sep 19;17(1):88. Epub 2017 Sep 19.
    Department of Urology, Erasmus MC, Wijtemaweg 80, Room Na 1724, 3015, CN, Rotterdam, The Netherlands.
    Background: Optimizing the patients' quality of life is one of the main goals in the urological management of spinal cord injury (SCI) patients. In this study we validated the Dutch SF-Qualiveen, a short questionnaire that measures the urinary-specific quality of life, in SCI patients. No such measure is yet available for this patient group. Read More

    A low psoas muscle volume correlates with a longer hospitalization after radical cystectomy.
    BMC Urol 2017 Sep 18;17(1):87. Epub 2017 Sep 18.
    Departments of Urology and Renal Transplantation, Yokohama City University Medical Center, 4-57 Urafune-cho, Minami-ku, Yokohama, Kanagawa, 2320024, Japan.
    Background: Recently, sarcopenia has been reported as a new predictor for patient outcomes or likelihood of post-operative complications. The purpose of this study was to evaluate the association of the psoas muscle volume with the length of hospitalization among patients undergoing radical cystectomy.

    Methods: A total of 63 (80. Read More

    The EEF1A2 gene expression as risk predictor in localized prostate cancer.
    BMC Urol 2017 Sep 18;17(1):86. Epub 2017 Sep 18.
    Department of Urology, University Medical Centre Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
    Background: Besides clinical stage and Gleason score, risk-stratification of prostate cancer in the pretherapeutic setting mainly relies on the serum PSA level. Yet, this is associated with many uncertainties. With regard to therapy decision-making, additional markers are needed to allow an exact risk prediction. Read More

    Increasing bladder capacity by foot stimulation in rats with spinal cord injuries.
    BMC Urol 2017 Sep 15;17(1):85. Epub 2017 Sep 15.
    Department of Urology, China Rehabilitation Research Center, Beijing, 100068, China.
    Background: This study was to explore the possibility that foot stimulation increased bladder capacity(BC) in rats with neurogenic bladder secondary to T10 spinal cord injuries.

    Methods: In 20 awake rats (stimulation group) with T10 spinal cord injuries, 5 repeat cystometrograms (CMGs) were recorded. The 1st and 2nd CMGs were performed without stimulation. Read More

    Should manual detorsion be a routine part of treatment in testicular torsion?
    BMC Urol 2017 Sep 15;17(1):84. Epub 2017 Sep 15.
    Department of Urology, Ankara Training and Research Hospital, 06340, Sukriye, Altındağ Ankara, Turkey.
    Background: It was aimed to investigate the efficiency and reliability of the manual detorsion (MD) procedure in patients diagnosed with testicular torsion (TT).

    Methods: A retrospective analysis was made of the data of 57 patients diagnosed with TT, comprising 20 patients with successful MD (Group I), 28 patients who underwent emergency orchiopexy (Group II), and 9 patients applied with orchiectomy (Group III). The groups were compared in respect of age, and duration of pain. Read More

    Application and analysis of retroperitoneal laparoscopic partial nephrectomy with sequential segmental renal artery clamping for patients with multiple renal tumor: initial experience.
    BMC Urol 2017 Sep 11;17(1):82. Epub 2017 Sep 11.
    Department of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 300 Guangzhou Road, Nanjing, 210029, China.
    Background: To explore the feasibility and safety of retroperitoneal laparoscopic partial nephrectomy with sequential segmental renal artery clamping for the patients with multiple renal tumor of who have solitary kidney or contralateral kidney insufficiency.

    Methods: Nine patients who have undergone retroperitoneal laparoscopic partial nephrectomy with sequential segmental renal artery clamping between October 2010 and January 2017 were retrospectively analyzed. Clinical materials and parameters during and after the operation were summarized. Read More

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