3,375 results match your criteria BMC Psychiatry[Journal]


A case report of cholinergic rebound syndrome following abrupt low-dose clozapine discontinuation in a patient with type I bipolar affective disorder.

BMC Psychiatry 2019 Feb 19;19(1):73. Epub 2019 Feb 19.

Psychopharmacology Unit, Clinical pharmacology and toxicology division, Acute Medicine Department, Geneva University Hospital, Geneva, Switzerland.

Background: Rebound cholinergic syndrome is a rare, but well known unwanted phenomenon occurring after abrupt clozapine discontinuation. There have been previous reported cases of cholinergic rebound in the literature; however, these reports described cholinergic rebound following cessation of high doses of clozapine in patients diagnosed with schizophrenia. Here, we report a case of rebound cholinergic syndrome and catatonia in a male patient three days after abrupt discontinuation of 50 mg of clozapine prescribed for type I bipolar affective disorder. Read More

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http://dx.doi.org/10.1186/s12888-019-2055-1DOI Listing
February 2019

Remote assessment of disease and relapse in major depressive disorder (RADAR-MDD): a multi-centre prospective cohort study protocol.

BMC Psychiatry 2019 Feb 18;19(1):72. Epub 2019 Feb 18.

King's College London, Institute of Psychiatry, Psychology and Neuroscience, London, UK.

Background: There is a growing body of literature highlighting the role that wearable and mobile remote measurement technology (RMT) can play in measuring symptoms of major depressive disorder (MDD). Outcomes assessment typically relies on self-report, which can be biased by dysfunctional perceptions and current symptom severity. Predictors of depressive relapse include disrupted sleep, reduced sociability, physical activity, changes in mood, prosody and cognitive function, which are all amenable to measurement via RMT. Read More

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http://dx.doi.org/10.1186/s12888-019-2049-zDOI Listing
February 2019

A stepped wedge cluster randomised trial of a cognitive remediation intervention in alcohol and other drug (AOD) residential treatment services.

BMC Psychiatry 2019 Feb 13;19(1):70. Epub 2019 Feb 13.

Ministry of Health NSW, 73 Miller St, North Sydney, NSW, 2060, Australia.

Background: Executive functioning impairment is common in substance use disorder and is a major risk factor for poor treatment outcomes, including treatment drop-out and relapse. Cognitive remediation interventions seek to improve executive functioning and offer a promising approach to increase the efficacy of alcohol and other drug (AOD) treatments and improve long-term therapeutic outcomes. This protocol describes a study funded by the NSW Agency for Clinical Innovation that assesses the effectiveness of delivering a six-week group-based intervention of cognitive remediation in an ecologically valid sample of people attending residential AOD treatment services. Read More

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http://dx.doi.org/10.1186/s12888-019-2044-4DOI Listing
February 2019

Cannabidiol enhancement of exposure therapy in treatment refractory patients with phobias: study protocol of a randomized controlled trial.

BMC Psychiatry 2019 Feb 13;19(1):69. Epub 2019 Feb 13.

Department of Experimental Psychology and Helmholtz Institute, Faculty of Social and Behavioural Sciences, Utrecht University, Utrecht, The Netherlands.

Background: Phobic anxiety disorders are among the most prevalent psychiatric disorders and are burdensome in terms of loss of quality of life and work productivity. Evidence-based treatments are relatively successful in the majority of patients, especially exposure therapy. However, a substantial subset of patients fails to achieve or stay in remission. Read More

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https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12
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http://dx.doi.org/10.1186/s12888-019-2022-xDOI Listing
February 2019
3 Reads

Mental distress and associated factors among Aksum University students, Ethiopia: a cross-sectional study.

BMC Psychiatry 2019 Feb 13;19(1):71. Epub 2019 Feb 13.

Department of Psychiatric Nursing, Aksum University College of Health Science, Referral Hospital, P.O. Box: 1010, Aksum, Ethiopia.

Background: Mental distress is becoming a common health problem in Ethiopia. The prevalence of mental distress is higher among university students than the general population. However, there is inadequate information in this regard in Ethiopia situations. Read More

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http://dx.doi.org/10.1186/s12888-019-2051-5DOI Listing
February 2019

Efficacy of a blended low-intensity internet-delivered psychological programme in patients with multimorbidity in primary care: study protocol for a randomized controlled trial.

BMC Psychiatry 2019 Feb 11;19(1):66. Epub 2019 Feb 11.

Primary Care Prevention and Health Promotion Research Network, RedIAPP, Madrid, Spain.

Background: The World Health Organization (WHO) has included comorbidity between depression and a chronic disease among the 10 leading global health priorities. Although there is a high prevalence of multimorbidity, health care systems are mainly designed for the management of individual diseases. Given the difficulty in delivering face-to-face psychological treatments, alternative models of treatment delivery have been proposed, emphasizing the role of technologies such as the Internet. Read More

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https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12
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http://dx.doi.org/10.1186/s12888-019-2037-3DOI Listing
February 2019
3 Reads

The GET READY relapse prevention programme for anxiety and depression: a mixed-methods study protocol.

BMC Psychiatry 2019 Feb 11;19(1):64. Epub 2019 Feb 11.

Department of Health, Sports & Welfare, Cluster Nursing, Inholland University of Applied Sciences, Research Group Mental Health Nursing, Amsterdam, The Netherlands.

Background: Since anxiety and depressive disorders often recur, self-management competencies are crucial for improving the long-term course of anxiety and depressive disorders. However, few relapse prevention programmes are available that focus on improving self-management. E-health combined with personal contact with a mental health professional in general practice might be a promising approach for relapse prevention. Read More

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https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12
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http://dx.doi.org/10.1186/s12888-019-2034-6DOI Listing
February 2019
2 Reads

Illness management and recovery: one-year follow-up of a randomized controlled trial in Danish community mental health centers: long-term effects on clinical and personal recovery.

BMC Psychiatry 2019 Feb 11;19(1):65. Epub 2019 Feb 11.

Copenhagen Research Center for Mental Health - CORE, Mental Health Center Copenhagen, Copenhagen University Hospital, Copenhagen, Denmark.

Background: Illness Management and Recovery (IMR) is a curriculum-based rehabilitation program for people with severe mental illness with the short-term aim of improving illness self-management and the long-term aim of helping people achieve clinical and personal recovery.

Method: Participants with schizophrenia or bipolar disorders were recruited from three community mental health centers in the Capital Region of Denmark and randomized to receive group-based IMR and treatment as usual or only the usual intervention. All outcomes were assessed at baseline, postintervention, and the one-year follow-up. Read More

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http://dx.doi.org/10.1186/s12888-019-2048-0DOI Listing
February 2019
2 Reads

Preventing the recurrence of depression with a Mediterranean diet supplemented with extra-virgin olive oil. The PREDI-DEP trial: study protocol.

BMC Psychiatry 2019 Feb 11;19(1):63. Epub 2019 Feb 11.

Psychiatry and Clinical Psychology Service, Hospital General de Gran Canaria Dr. Negrin, Las Palmas de Gran Canaria, Spain.

Background: The role of dietary patterns in the prevention of unipolar depression has been analyzed in several epidemiological studies. The primary aims of this study are to determine the effectiveness of an extra-olive oil-enriched Mediterranean diet in reducing the recurrence of depression and improving the symptoms of this condition.

Methods: Multicenter, two-arm, parallel-group clinical trial. Read More

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http://dx.doi.org/10.1186/s12888-019-2036-4DOI Listing
February 2019

Variation in the CACNB2 gene is associated with functional connectivity of the Hippocampus in bipolar disorder.

BMC Psychiatry 2019 Feb 11;19(1):62. Epub 2019 Feb 11.

Department of Psychiatry, First Affiliated Hospital, China Medical University, 155 Nanjing North Street, Shenyang, 110001, Liaoning, China.

Background: Calcium voltage-gated channel auxiliary subunit β2 is a protein that, in humans, is encoded by the CACNB2 gene. The β2 subunit is an auxiliary protein of voltage-gated calcium channels, which is predominantly expressed in hippocampal pyramidal neurons. A single-nucleotide polymorphism at the CACNB2 gene (rs11013860) has been reported in genome-wide association studies to be associated with bipolar disorder (BD). Read More

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http://dx.doi.org/10.1186/s12888-019-2040-8DOI Listing
February 2019
1 Read

Prevalence and factors associated with emotional and behavioural difficulties among children living with HIV in Malawi: a cross-sectional study.

BMC Psychiatry 2019 Feb 8;19(1):60. Epub 2019 Feb 8.

Kamuzu College of Nursing, University of Malawi, Blantyre, Malawi.

Background: Approximately 84,000 children under the age of 15 years are living with HIV in Malawi. Although the survival rate of children living with HIV in Malawi has improved due to the increased availability of antiretroviral medications, these children continue to experience numerous challenges negatively impacting on their mental health. The aim of this study was to investigate the prevalence of, and factors associated with, emotional and behavioural difficulties in children aged between 6 and 12 years living with HIV in Malawi. Read More

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https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12
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http://dx.doi.org/10.1186/s12888-019-2046-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368705PMC
February 2019
1 Read

An integrated, collaborative healthcare model for the early diagnosis and management of dementia: Preliminary audit results from the first transdisciplinary service integrating family medicine and geriatric psychiatry services to the heart of patients' homes.

BMC Psychiatry 2019 Feb 8;19(1):61. Epub 2019 Feb 8.

Choa Chu Kang Polyclinic, National University Polyclinics, 2 Teck Whye Crescent #01-00, Singapore, 688846, Singapore.

Background: The number of dementia cases is expected to rise exponentially over the years in many parts of the world. Collaborative healthcare partnerships are envisaged as a solution to this problem. Primary care physicians form the vanguard of early detection of dementia and influence clinical care that these patients receive. Read More

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http://dx.doi.org/10.1186/s12888-019-2033-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368696PMC
February 2019

The dynamical signature of anhedonia in major depressive disorder: positive emotion dynamics, reactivity, and recovery.

BMC Psychiatry 2019 Feb 8;19(1):59. Epub 2019 Feb 8.

Research group of Quantitative Psychology and Individual Differences, KU Leuven, Tiensestraat 102 - bus 3713, 3000, Leuven, Belgium.

Background: Major Depressive Disorder (MDD) is the leading cause of disability worldwide. The cardinal features of MDD are depressed mood and anhedonia. Anhedonia is defined as a "markedly diminished interest or pleasure in all, or almost all, activities of the day", and has generally been investigated on group-level using retrospective data (e. Read More

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http://dx.doi.org/10.1186/s12888-018-1983-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368777PMC
February 2019

Effects of surgical repair of obstetric fistula on severity of depression and anxiety in Ethiopia.

BMC Psychiatry 2019 Feb 7;19(1):58. Epub 2019 Feb 7.

Department of Health Studies, University of South Africa, Pretoria, South Africa.

Background: The surgical repair of fistula can address the physical symptoms, but may not end the psychological challenges that women with fistula face. There are a few studies that focus on women with this condition in Ethiopia. Hence, the aim of this study was to determine the effects of surgical repair of obstetric fistula on the severity of depression and anxiety in women with obstetric fistula in Ethiopia. Read More

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http://dx.doi.org/10.1186/s12888-019-2045-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367812PMC
February 2019
1 Read

Daily variation in post traumatic stress symptoms in individuals with and without probable post traumatic stress disorder.

BMC Psychiatry 2019 Feb 4;19(1):56. Epub 2019 Feb 4.

Center for the Study of Traumatic Stress, Department of Psychiatry, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD, 20814, USA.

Background: Little is known about the extent to which post traumatic stress symptoms (PTSS) vary from day to day in individuals with post traumatic stress disorder (PTSD). This study examined the variation of PTSS by day of the week, and whether daily or day of week variation differs between individuals with and without probable PTSD.

Methods: Subjects (N = 80) were assessed for probable PTSD at enrollment. Read More

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http://dx.doi.org/10.1186/s12888-019-2041-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360743PMC
February 2019
2 Reads

Exploring mental health professionals' practice in relation to smoke-free policy within a mental health trust: a qualitative study using the COM-B model of behaviour.

BMC Psychiatry 2019 Feb 4;19(1):54. Epub 2019 Feb 4.

Department of Behavioural Science and Health, University College London, 1-19 Torrington Place, London, WC1E 6BT, UK.

Background: Smoking has played a significant role in the historical culture of mental healthcare settings. Mental health professionals (MHPs) often hold dismissive attitudes regarding the importance of smoking cessation in the context of mental healthcare. In 2007, English mental health inpatient buildings were required by law to become smoke-free, and healthcare trusts have more recently begun to implement comprehensive policies (i. Read More

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http://dx.doi.org/10.1186/s12888-019-2029-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360690PMC
February 2019
1 Read

A systematic review of service models and evidence relating to the clinically operated community-based residential mental health rehabilitation for adults with severe and persisting mental illness in Australia.

BMC Psychiatry 2019 Feb 4;19(1):55. Epub 2019 Feb 4.

School of Public Health, The University of Queensland, Herston, 4006, Australia.

Background: Clinically operated community-based residential rehabilitation units (Community Rehabilitation Units) are resource intensive services supporting a small proportion of the people with severe and persisting mental illness who experience difficulties living in the community. Most consumers who engage with these services will be diagnosed with schizophrenia or a related disorder. This review seeks to: generate a typology of service models, describe the characteristics of the consumers accessing these services, and synthesise available evidence about consumers' service experiences and outcomes. Read More

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http://dx.doi.org/10.1186/s12888-019-2019-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360669PMC
February 2019
2 Reads

Somatic and sociodemographic predictors of depression outcome among depressed patients with coronary artery disease - a secondary analysis of the SPIRR-CAD study.

BMC Psychiatry 2019 Feb 4;19(1):57. Epub 2019 Feb 4.

Department of Psychosomatics and Psychotherapy, University of Cologne, Cologne, Germany.

Background: Depressive symptoms are common in patients with coronary artery disease (CAD) and are associated with an unfavourable outcome. Establishing prognostic patient profiles prior to the beginning of mental health care may facilitate higher efficacy of targeted interventions. The aim of the current study was to identify sociodemographic and somatic predictors of depression outcome among depressed patients with CAD. Read More

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http://dx.doi.org/10.1186/s12888-019-2026-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360727PMC
February 2019
1 Read

Complementary and alternative medicine use in adults with autism spectrum disorder in Germany: results from a multi-center survey.

BMC Psychiatry 2019 Feb 1;19(1):53. Epub 2019 Feb 1.

Department of Child and Adolescent Psychiatry, LVR-Klinikum Düsseldorf/ Heinrich-Heine University Düsseldorf, Bergische Landstr. 2, 40629, Düsseldorf, Germany.

Background: Complementary and Alternative Medicine (CAM) is widely used both in the general population and for the treatment of somatic and psychiatric disorders. Studies on CAM use among patients with autism spectrum disorder (ASD) have so far only focused on children and adolescents. The aim of this study was to investigate patterns of CAM use among adults with ASD. Read More

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http://dx.doi.org/10.1186/s12888-019-2043-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359789PMC
February 2019
1 Read

MyCompass in a Swedish context - lessons learned from the transfer of a self-guided intervention targeting mental health problems.

BMC Psychiatry 2019 Jan 31;19(1):51. Epub 2019 Jan 31.

Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet & Stockholm Health Care Services, Stockholm County Council, Norra Stationsgatan 69, 7tr, SE-113 64, Stockholm, Sweden.

Background: Depression and anxiety is a major public health problem, in Sweden and internationally. Internet-based interventions are increasingly acknowledged as promising approaches for individuals with varying degrees of mental health problems. We present findings from the implementation of myCompass, a fully automated self-guided intervention of Australian origin, in a Swedish context. Read More

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http://dx.doi.org/10.1186/s12888-019-2039-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357356PMC
January 2019
1 Read

Clinical guidelines for the management of depression with specific comorbid psychiatric conditions French recommendations from experts (the French Association for Biological Psychiatry and Neuropsychopharmacology and the fondation FondaMental).

BMC Psychiatry 2019 Jan 30;19(1):50. Epub 2019 Jan 30.

Département des Urgences et Post-Urgences Psychiatriques, Centre Expert Dépression Résistante FondaMental, CHU Montpellier, Univ Montpellier, Montpellier, France.

Background: Recommendations for pharmacological treatments of major depression with specific comorbid psychiatric conditions are lacking.

Method: The French Association for Biological Psychiatry and Neuropsychopharmacology and the fondation FondaMental developed expert consensus guidelines for the management of depression based on the RAND/UCLA Appropriatneness Method. Recommendations for lines of treatment are provided by the scientific committee after data analysis and interpretation of the results of a survey of 36 psychiatrist experts in the field of major depression and its treatments. Read More

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http://dx.doi.org/10.1186/s12888-019-2025-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354367PMC
January 2019
1 Read

More than depression: a multi-dimensional assessment of postpartum distress symptoms before and after a residential early parenting program.

BMC Psychiatry 2019 Jan 29;19(1):48. Epub 2019 Jan 29.

Faculty of Medicine, Nursing and Health Sciences, Monash Institute of Cognitive and Clinical Neurosciences, School of Psychological Sciences, Monash University, 18 Innovation Walk, Clayton Campus, Clayton, VIC, 3800, Australia.

Introduction: Parents are vulnerable to psychological distress symptoms in the postpartum period. It is routine to screen for depressive symptoms, but anxiety, stress, fatigue, irritability and insomnia symptoms are less often assessed despite their prevalence. This study aimed to assess multiple dimensions of psychological distress, and their reliable change and clinically significant change among women admitted to a residential program for assistance with unsettled infant behaviors (UIB). Read More

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http://dx.doi.org/10.1186/s12888-019-2024-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352433PMC
January 2019
1 Read

Correction to: Risk and protective factors for mental health morbidity in a community sample of female-to-male trans-masculine adults.

BMC Psychiatry 2019 Jan 28;19(1):45. Epub 2019 Jan 28.

Harvard Medical School, 300 Longwood Ave, Boston, MA, USA.

Following publication of the original article [1], we have been notified of the below corrections. Read More

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http://dx.doi.org/10.1186/s12888-019-2028-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348629PMC
January 2019

Prevalence and determinants of symptoms of antenatal common mental disorders among women who had recently experienced an earthquake: a systematic review.

BMC Psychiatry 2019 Jan 28;19(1):47. Epub 2019 Jan 28.

School of Public Health and Preventive Medicine, Monash University, Level 4, 553 St Kilda Rd, Melbourne, Victoria, 3004, Australia.

Background: Antenatal common mental disorders (CMDs) including anxiety, depressive, adjustment, and somatoform disorders are prevalent worldwide. There is emerging evidence that experiencing a natural disaster might increase the risk of antenatal CMDs. This study aimed to synthesise the evidence about the prevalence and determinants of clinically-significant symptoms of antenatal CMDs among women who had recently experienced an earthquake. Read More

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http://dx.doi.org/10.1186/s12888-018-1986-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348613PMC
January 2019
1 Read
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Effectiveness of a self-management training for patients with chronic and treatment resistant anxiety or depressive disorders on quality of life, symptoms, and empowerment: results of a randomized controlled trial.

BMC Psychiatry 2019 Jan 28;19(1):46. Epub 2019 Jan 28.

Behavioural Science Institute, Radboud University Medical Center, PO Box 9104, 6500, HE, Nijmegen, The Netherlands.

Background: Anxiety and depressive disorders are common mental disorders. A substantial part of patients does not achieve symptomatic remission after treatment in specialized services. Current care as usual (CAU) for these patients consists of long-term supportive contacts. Read More

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https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12
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http://dx.doi.org/10.1186/s12888-019-2013-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348638PMC
January 2019
5 Reads

Hyperactivity/restlessness is associated with increased functional connectivity in adults with ADHD: a dimensional analysis of resting state fMRI.

BMC Psychiatry 2019 Jan 25;19(1):43. Epub 2019 Jan 25.

Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.

Background: Adult attention-deficit/hyperactivity disorder (ADHD) is a serious and frequent psychiatric disorder of multifactorial pathogenesis. Several lines of evidence support the idea that ADHD is, in its core, a disorder of dysfunctional brain connectivity within and between several neurofunctional networks. The primary aim of this study was to investigate associations between the functional connectivity within resting state brain networks and the individual severity of core ADHD symptoms (inattention, hyperactivity, and impulsivity). Read More

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http://dx.doi.org/10.1186/s12888-019-2031-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347794PMC
January 2019
1 Read

An outreach collaborative model for early identification and treatment of mental disorder in Danish workplaces.

BMC Psychiatry 2019 Jan 24;19(1):40. Epub 2019 Jan 24.

Clinic for Occupational Medicine, Aalborg University Hospital, Havrevangen 1, 9000, Aalborg, Denmark.

Background: Depression and anxiety are prevalent mental disorders among the working population with potentially high personal and financial cost. The overall aim of this study was to test the applicability of an outreach collaborative model for early identification and treatment of clinical and sub-clinical mental disorders among Danish employees. This applicability was examined by I) investigating the fractions of identified and treated clinical and subclinical cases, II) describing the distribution and characteristics of cases identified and III) investigating the effect of allocated treatment. Read More

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https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12
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http://dx.doi.org/10.1186/s12888-019-2027-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345055PMC
January 2019
4 Reads

Extending access to a web-based mental health intervention: who wants more, what happens to use over time, and is it helpful? Results of a concealed, randomized controlled extension study.

BMC Psychiatry 2019 Jan 24;19(1):39. Epub 2019 Jan 24.

Women's College Hospital Institute for Health Systems Solutions and Virtual Care, Women's College Hospital, 76 Grenville St, Toronto, Ontario, M5S 1B2, Canada.

Background: Web-based mental health applications may be beneficial, but adoption is often low leaving optimal implementation and payment models unclear. This study examined which users were interested in extended access to a web-based application beyond an initial 3-month trial period and evaluated if an additional 3 months of access was beneficial.

Methods: This study was a concealed extension of a multi-center, pragmatic randomized controlled trial that assessed the benefit of 3 months of access to the Big White Wall (BWW), an anonymous web-based moderated, multi-component mental health application offering self-directed activities and peer support. Read More

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http://dx.doi.org/10.1186/s12888-019-2030-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345062PMC
January 2019

Effects of dog-assisted therapy in adults with dementia: a systematic review and meta-analysis.

BMC Psychiatry 2019 Jan 24;19(1):41. Epub 2019 Jan 24.

Unidad de Investigación para la Generación y Síntesis de Evidencias en Salud, Universidad San Ignacio de Loyola, Lima, Peru.

Background: Dog-assisted therapy (DAT) is a non-pharmacological intervention based on the interaction between patients and dogs, which has been proposed to help adults with dementia. However, evidence to support it is lacking. Thus, we aim to evaluate the effects of DAT on this population and to assess the certainty of the evidence of the RCTs estimates. Read More

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http://dx.doi.org/10.1186/s12888-018-2009-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345014PMC
January 2019

A case report of the successful administration of clozapine in the face of myocardial infarction, pulmonary embolism and hyperlipidaemia resulting in the termination of long-term seclusion.

Authors:
Alex Till Ed Silva

BMC Psychiatry 2019 Jan 23;19(1):37. Epub 2019 Jan 23.

Ashworth Hospital, Mersey Care NHS Trust, Parkbourn, Maghull, Liverpool, Merseyside, L31 1HW, UK.

Background: Cardiometabolic health significantly impacts on the mortality of people with severe mental illness. Clozapine has the greatest efficacy for Treatment Resistant Schizophrenia (TRS) but the greatest negative impact on cardiometabolic health. Balancing the risks and benefits of treatment, dignity, autonomy, liberty, mental and physical health can be challenging, particularly when imposing interventions with potentially life threatening adverse events, such as clozapine. Read More

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http://dx.doi.org/10.1186/s12888-018-2001-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343332PMC
January 2019
2 Reads

Associations between childhood maltreatment and adult depression: a mediation analysis.

BMC Psychiatry 2019 Jan 22;19(1):36. Epub 2019 Jan 22.

Department of Psychology, LMU Munich, Munich, Germany.

Background: There is ample evidence showing that childhood maltreatment (CM) is a risk factor for the development of depression in adulthood. However, little is known about the psychological processes mediating this relationship. This study used a large community sample to investigate the mediating role of emotional, cognitive and/or interpersonal dysfunctions on the one hand and posttraumatic stress disorder symptoms on the other hand. Read More

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http://dx.doi.org/10.1186/s12888-019-2016-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343339PMC
January 2019

A qualitative exploration of service user views about using digital health interventions for self-management in severe mental health problems.

BMC Psychiatry 2019 Jan 21;19(1):35. Epub 2019 Jan 21.

Division of Psychology and Mental Health, Medicine and Health, Manchester Academic Health Science Centre, School of Health Sciences, Faculty of Biology University of Manchester, Brunswick Street, Manchester, UK.

Background: The development of digital health interventions (DHIs) for severe mental health problems is fast-paced. Researchers are beginning to consult service users to inform DHIs; however, much of this involvement has been limited to feedback on specific interventions post-DHI development. This study had two aims: 1. Read More

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http://dx.doi.org/10.1186/s12888-018-1979-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341527PMC
January 2019

Prevalence, correlates for early neurological disorders and association with functioning among children and adolescents with HIV/AIDS in Uganda.

BMC Psychiatry 2019 Jan 21;19(1):34. Epub 2019 Jan 21.

Mental Health Project, MRC/UVRI and LSHTM Uganda Research Unit, P. O. Box 49, Entebbe, Uganda.

Background: The aim of this study was to determine the prevalence of neurological disorders and their associated correlates and relations with clinical and behavioural problems among children and adolescents with HIV/AIDS (CA-HIV).

Methods: This study involved a sample of 1070 CA-HIV/caregiver dyads who were evaluated at their 6-month follow-up visit as part of their participation in the longitudinal study, 'Mental health among HIV infected CHildren and Adolescents in KAmpala and Masaka, Uganda (the CHAKA study)'. Participants completed an extensive battery of measures that included a standardized DSM-5- referenced rating scale, the parent version (5-18 years) of the Child and Adolescent Symptom Inventory-5 (CASI-5). Read More

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http://dx.doi.org/10.1186/s12888-019-2023-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341558PMC
January 2019

Prevalence and management practice of first generation antipsychotics induced side effects among schizophrenic patients at Amanuel Mental Specialized Hospital, central Ethiopia: cross-sectional study.

BMC Psychiatry 2019 Jan 18;19(1):32. Epub 2019 Jan 18.

Department of Clinical Pharmacy and Pharmacology, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.

Background: First-generation antipsychotics (FGAs) are associated with a range of adverse events which can significantly reduce patients' quality of life and contribute to non-adherence. The aim of this study was to assess the prevalence and management practice of first generation antipsychotics induced side effects among schizophrenic patients.

Methods: The study was conducted at Amanuel Mental Specialized Hospital from March to June, 2017. Read More

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http://dx.doi.org/10.1186/s12888-018-1999-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339381PMC
January 2019
6 Reads

Comorbid tobacco and other substance use and symptoms of anxiety and depression among hospitalised orthopaedic trauma patients.

BMC Psychiatry 2019 Jan 17;19(1):28. Epub 2019 Jan 17.

School of Medicine and Public Health, Faculty of Health and Medicine, University of Newcastle, 1 University Drive, Callaghan, NSW, 2308, Australia.

Background: No study has examined the prevalence of tobacco, other substance use, and symptoms of anxiety and depression, and rates of comorbidities among the orthopaedic trauma population, despite the impact they have on recovery from surgery. This study aims to 1) describe the rates of symptoms and substance use; 2) compare rates of symptoms and substance use among smokers versus non-smokers; and 3) examine the relationship between symptoms and substance use with smoking status.

Methods: A cross-sectional survey of orthopaedic trauma patients was conducted in two Australian public hospitals. Read More

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https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12
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http://dx.doi.org/10.1186/s12888-019-2021-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337866PMC
January 2019
4 Reads

Amplitude of low-frequency fluctuation (ALFF) may be associated with cognitive impairment in schizophrenia: a correlation study.

BMC Psychiatry 2019 Jan 17;19(1):30. Epub 2019 Jan 17.

Department of Psychiatry, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, 110001, People's Republic of China.

Background: Cognitive impairments are prominent in schizophrenia (SZ). Imaging studies have demonstrated that functional changes of several areas of the brain exist in SZ patients. The relationships between these two indexes are largely unexplored in SZ. Read More

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https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12
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http://dx.doi.org/10.1186/s12888-018-1992-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337807PMC
January 2019
6 Reads
2.210 Impact Factor

A cluster randomized controlled trial of an online psychoeducational intervention for people with a family history of depression.

BMC Psychiatry 2019 Jan 17;19(1):29. Epub 2019 Jan 17.

School of Psychiatry, UNSW, Sydney, Australia.

Background: People with a family history of major depressive disorder (MDD) or bipolar disorder (BD) report specific psychoeducational needs that are unmet by existing online interventions. This trial aimed to test whether an interactive website for people at familial risk for depression (intervention) would improve intention to adopt, or actual adoption of, depression prevention strategies (primary outcome) and a range of secondary outcome measures.

Methods: In this cluster randomised trial, primary care practises were randomised to either provide the link to the intervention or the control website. Read More

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https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12
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http://dx.doi.org/10.1186/s12888-018-1994-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337794PMC
January 2019
5 Reads

A randomized controlled trial of cognitive remediation for a national cohort of forensic patients with schizophrenia or schizoaffective disorder.

BMC Psychiatry 2019 Jan 15;19(1):27. Epub 2019 Jan 15.

Department of Psychiatry Trinity College Dublin, the University of Dublin, Dublin, Ireland.

Background: Evidence is accumulating that Cognitive Remediation Training (CRT) is effective for ameliorating cognitive deficits experienced by patients with schizophrenia and accompanying functional impairment. There has been no randomized controlled trial of CRT using a nationally representative population of forensic patients, despite the significant cognitive deficits frequently present within this group.

Methods: Sixty-five patients with schizophrenia or schizoaffective disorder were enrolled in a single blind randomized controlled trial of CRT versus treatment as usual (TAU); representing 94% of those eligible within a national forensic cohort. Read More

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http://dx.doi.org/10.1186/s12888-019-2018-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334394PMC
January 2019
2 Reads

Group schema-focused therapy enriched with psychomotor therapy versus treatment as usual for older adults with cluster B and/or C personality disorders: a randomized trial.

BMC Psychiatry 2019 Jan 15;19(1):26. Epub 2019 Jan 15.

Department of Psychiatry, University of Groningen, University Medical Center Groningen, Post office box 30.001, 9700, RB, Groningen, The Netherlands.

Background: Several types of psychotherapy have been proven successful in the treatment of personality disorders in younger age groups, however studies among older patients are lacking. We developed a group schema-focused therapy (SFT) enriched with psychomotor therapy (PMT) for older adults with cluster B and/or C personality disorders. This paper describes the design of a randomized controlled trial (RCT). Read More

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https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12
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http://dx.doi.org/10.1186/s12888-018-2004-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334382PMC
January 2019
4 Reads