2,116 results match your criteria BMC Pediatrics [Journal]


Clinical evaluation of severe neonatal Hyperbilirubinaemia in a resource-limited setting: a 4-year longitudinal study in south-East Nigeria.

BMC Pediatr 2018 Jun 23;18(1):202. Epub 2018 Jun 23.

Department of Paediatrics, Enugu State University of Science and Technology, Enugu, Enugu State, Nigeria.

Background: Neonatal hyperbilirubinaemia is one of the commonest causes of hospital visit in the neonatal period. When severe, it is a leading cause of irreversible neurological and musculoskeletal disability. Prompt recognition and timely interventions are imperative for a drastic reduction in complications associated with severe hyperbilirubinaemia in newborns. Read More

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The antipyretic efficacy and safety of propacetamol compared with dexibuprofen in febrile children: a multicenter, randomized, double-blind, comparative, phase 3 clinical trial.

BMC Pediatr 2018 Jun 23;18(1):201. Epub 2018 Jun 23.

Department of Pediatrics, College of Medicine, The Catholic University of Korea, 222, Banpodaero, Seocho-gu, Seoul, 06591, Republic of Korea.

Background: We aimed to compare the antipyretic efficacy, safety, and tolerability between oral dexibuprofen and intravenous propacetamol in children with upper respiratory tract infection (URTI) presenting with fever.

Methods: Patients aging from 6 months to 14 years admitted for URTI with axillary body temperature ≥ 38.0 °C were enrolled and randomized into the study or control group. Read More

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June 2018
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A case report of hemolytic streptococcal gangrene in the danger triangle of the face with thrombocytopenia and hepatitis.

BMC Pediatr 2018 Jun 22;18(1):198. Epub 2018 Jun 22.

Department of Stomatology, Children's Hospital, Zhejiang University School of Medicine, NO.3333 Binsheng Road, Hangzhou, 310052, Zhejiang Province, People's Republic of China.

Background: Hemolytic streptococcus gangrene is a life threatening invasive bacterial infection. Hemolytic streptococcus gangrene in the danger triangle of the face is too lethal to operate. A case of the confirmed hemolytic streptococcus gangrene in the danger triangle of the face caused by Group A beta-hemolytic streptococcus (GAS) in 20-months old boy is presented to draw attention of clinicians to this uncommon but frequently fatal infection. Read More

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Effectiveness of intravenous immunoglobulin alone and intravenous immunoglobulin combined with high-dose aspirin in the acute stage of Kawasaki disease: study protocol for a randomized controlled trial.

BMC Pediatr 2018 Jun 22;18(1):200. Epub 2018 Jun 22.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, #123 Da-Pei Road, Niaosong District, Kaohsiung, 83301, Taiwan.

Background: Kawasaki disease (KD) is an acute febrile systemic vasculitis most commonly seen in children under 5 years old. High-dose aspirin is often administered, but the duration of such treatment varies. Many centers reduce the aspirin dose once the patient is afebrile, even before treating said patient with intravenous immunoglobulin (IVIG). Read More

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June 2018
2 Reads

Testing the feasibility of eliciting preferences for health states from adolescents using direct methods.

BMC Pediatr 2018 Jun 22;18(1):199. Epub 2018 Jun 22.

Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA.

Background: Measuring adolescents' preferences for health states can play an important role in evaluating the delivery of pediatric healthcare. However, formal evaluation of the common direct preference elicitation methods for health states has not been done with adolescents. Therefore, the purpose of this study is to test how these methods perform in terms of their feasibility, reliability, and validity for measuring health state preferences in adolescents. Read More

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Ursodeoxycholic acid versus phenobarbital for cholestasis in the Neonatal Intensive Care Unit.

BMC Pediatr 2018 Jun 20;18(1):197. Epub 2018 Jun 20.

Department of Pediatrics, Children's Mercy Hospital, University of Missouri Kansas City School of Medicine, 2401 Gillham Rd, Kansas City, MO, 64108, USA.

Background: Although neonates and young infants with cholestasis are commonly treated with either phenobarbital or ursodeoxycholic acid (ursodiol), there is no evidence that phenobarbital is effective for this indication. Our objective was to compare the effectiveness of ursodiol and phenobarbital for the treatment of cholestasis in a diverse NICU population.

Methods: This is a retrospective cohort study including infants with cholestasis who were admitted to a Level IV NICU between January 2010 and December 2015. Read More

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Is there an association between vitamin D deficiency and adenotonsillar hypertrophy in children with sleep-disordered breathing?

BMC Pediatr 2018 Jun 19;18(1):196. Epub 2018 Jun 19.

Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul, 06591, Republic of Korea.

Background: Low vitamin D levels have been linked to the risk of sleep-disordered breathing (SDB) in children. Although adenotonsillar hypertrophy (ATH) is the major contributor to childhood SDB, the relationship between ATH and serum vitamin D is uncertain. We therefore investigated the relationship between vitamin D levels and associated factors in children with ATH. Read More

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Changing outpatient referral patterns in a small pediatric nephrology practice.

BMC Pediatr 2018 Jun 19;18(1):195. Epub 2018 Jun 19.

Department of Pediatrics, Division of Nephrology, University of Washington, Seattle, WA, USA.

Background: We have noted a large number of referrals for abnormal kidney imaging and laboratory tests and postulated that such referrals have increased significantly over time. Understanding changes in referral patterns is helpful in tailoring education and communication between specialists and primary providers.

Methods: We performed a retrospective chart review of new patient referrals to Mary Bridge Children's Nephrology clinic for early (2002 to 2004) and late (2011 to 2013) cohorts. Read More

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Knowledge, attitudes and misconceptions of Italian healthcare professionals regarding fever management in children.

BMC Pediatr 2018 Jun 18;18(1):194. Epub 2018 Jun 18.

Department of Health Sciences, Anna Meyer Children's University Hospital, University of Florence, Viale Pieraccini, 24, 50100, Florence, Italy.

Background: Fever phobia is still a major issue in paediatrics. We report knowledge of a sample of Italian paediatricians performed six years after the release of the Italian guidelines for the management of fever in children (IFG).

Methods: A questionnaire, developed following the IFG recommendations and previously administered to 300 paediatricians in 2012, was proposed to all the paediatricians attending the 2015 National Congress of Practice Paediatrics, held in Florence, Italy. Read More

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June 2018
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A case of Metaplastic atrophic gastritis in immune Dysregulation, Polyendocrinopathy, Enteropathy, X-linked (IPEX) syndrome.

BMC Pediatr 2018 Jun 15;18(1):191. Epub 2018 Jun 15.

Gastroenterology Department, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Background: Autoimmune metaplastic atrophic gastritis is a chronic progressive inflammatory condition. The clinical spectrum includes pernicious anemia, atrophic gastritis, antibodies to parietal cell antigens and intrinsic factor, achlorhydria, hypergastrinemia and carcinoma. It is rare in paediatric cohorts. Read More

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June 2018
2 Reads

Health related quality of life of preterm born children at three years in a sub urban district in Sri Lanka: a retrospective cohort study.

BMC Pediatr 2018 Jun 15;18(1):193. Epub 2018 Jun 15.

World Bank Country Office, Colombo, 05, Sri Lanka.

Background: Preterm birth leads to multiple morbidities affecting the health of a child. Lack of information on the health impact of prematurity hinders the possibility of any effective public health interventions in this regard. Our aim was to determine the association between preterm birth and Health-Related Quality of Life (HRQOL) among 3 years old children in the Gampaha district, Sri Lanka. Read More

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June 2018
3 Reads

Serum and urine FGF23 and IGFBP-7 for the prediction of acute kidney injury in critically ill children.

BMC Pediatr 2018 Jun 15;18(1):192. Epub 2018 Jun 15.

Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, JiangSu province, China.

Background: Fibroblast growth factor 23 (FGF23) and insulin-like growth factor binding protein 7 (IGFBP-7) are suggested to be biomarkers for predicting acute kidney injury (AKI). We compared them with proposed AKI biomarker of cystatin C (CysC), and aimed (1) to examine whether concentrations of these biomarkers vary with age, body weight, illness severity assessed by pediatric risk of mortality III score, and kidney function assessed by estimated glomerular filtration rate (eGFR), (2) to determine the association between these biomarkers and AKI, and (3) to evaluate whether these biomarkers could serve as early independent predictors of AKI in critically ill children.

Methods: This prospective single center study included 144 critically ill patients admitted to the pediatric intensive care unit (PICU) regardless of diagnosis. Read More

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June 2018
2 Reads

Indirect neonatal hyperbilirubinemia in hospitalized neonates on the Thai-Myanmar border: a review of neonatal medical records from 2009 to 2014.

BMC Pediatr 2018 Jun 12;18(1):190. Epub 2018 Jun 12.

Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand.

Background: Indirect neonatal hyperbilirubinemia (INH) is a common neonatal disorder worldwide which can remain benign if prompt management is available. However there is a higher morbidity and mortality risk in settings with limited access to diagnosis and care. The manuscript describes the characteristics of neonates with INH, the burden of severe INH and identifies factors associated with severity in a resource-constrained setting. Read More

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June 2018
3 Reads

Occurrence of erythema migrans in children with Lyme neuroborreliosis and the association with clinical characteristics and outcome - a prospective cohort study.

BMC Pediatr 2018 Jun 11;18(1):189. Epub 2018 Jun 11.

Pediatric Department, Falun County Hospital, Falun, Sweden.

Background: Erythema migrans (EM) is the most common manifestation of Lyme borreliosis (LB), caused by the spirochete Borrelia burgdorferi sensu lato. The infection can disseminate into the nervous system and cause Lyme neuroborreliosis (LNB), the second most frequent LB manifestation in children. The aim of this prospective cohort study is to describe the occurrence of EM among children with LNB and to evaluate possible differences in clinical characteristics or outcome between LNB patients with and without EM. Read More

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Mother's obesity and high child's waist circumference are predictive factors of severe child's obesity: an observational study in French Guiana.

BMC Pediatr 2018 Jun 9;18(1):188. Epub 2018 Jun 9.

Department of Pediatric Medicine and Surgery, Cayenne Hospital, Rue des flamboyants, BP 6006, 97306, Cayenne Cedex, French Guiana.

Background: This study aims to describe the predictive factors of severe obesity in children followed in French Guiana.

Methods: In this observational study, the patients from the French Guianese Childhood Obesity Group database were prospectively included, after giving a statement of patient's non opposition.

Results: Our group classifications revealed that 36 of 150 (24%) participants were classified as being metabolically abnormal obesity" (MAO), while 114 of 150 (76%) were categorized as metabolically normal obesity" (MNO). Read More

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BMI z-score in obese children is a poor predictor of adiposity changes over time.

BMC Pediatr 2018 Jun 8;18(1):187. Epub 2018 Jun 8.

University of Wisconsin, UW Health- University Hospital, 600 Highland Ave, Madison, WI, 53792, USA.

Background: The age and sex standardized body mass index (BMIz) is a simple and widely utilized screening tool for obesity in children and adolescents. The purpose of this study was to evaluate the relationship between the BMIz trajectory versus the percent body fat (%FAT) trajectory, and if BMIz could predict significant changes in %FAT in a sample of obese children and adolescents.

Methods: In this longitudinal observational study, body composition was measured by dual energy x-ray absorptiometry (DXA) in obese children within a multidisciplinary pediatric fitness clinic at an academic medical center over a 3-year time period. Read More

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Developing "My Asthma Diary": a process exemplar of a patient-driven arts-based knowledge translation tool.

BMC Pediatr 2018 Jun 5;18(1):186. Epub 2018 Jun 5.

Faculty of Nursing, University of Alberta, Level 3, Edmonton Clinic Health Academy, 11405-87 Avenue, Alberta, T6G 1C9, Canada.

Background: Although it is well established that family-centered education is critical to managing childhood asthma, the information needs of parents of children with asthma are not being met through current educational approaches. Patient-driven educational materials that leverage the power of the storytelling and the arts show promise in communicating health information and assisting in illness self-management. However, such arts-based knowledge translation approaches are in their infancy, and little is known about how to develop such tools for parents. Read More

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Elevated IgM levels as a marker for a unique phenotype in patients with Ataxia telangiectasia.

BMC Pediatr 2018 Jun 4;18(1):185. Epub 2018 Jun 4.

The Claudio Cohen Department of Pediatric Intensive Care, The Edmond and Lily Safra Children's Hospital, Tel- Hashomer, Israel.

Background: Ataxia telangiectasia (AT) is a rare, multi-systemic, genetic disorder. Mutations in the ATM gene cause dysfunction in cell-cycle, apoptosis and V (D) J recombination leading to neurodegeneration, cellular, humoral immunodeficiencies and predisposition to malignancies. Previous studies have suggested that a sub-group of AT patients with elevated IgM levels have a distinct and more severe phenotype. Read More

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Clinical and molecular report of c.1331 + 1G > A mutation of the AAAS gene in a Moroccan family with Allgrove syndrome: a case report.

BMC Pediatr 2018 Jun 4;18(1):184. Epub 2018 Jun 4.

Pediatrics III, Children's Hospital of Rabat, University Mohammed V, Belarbi El Alaoui Avenue, 6203, Rabat, PB, Morocco.

Background: Allgrove syndrome is a rare autosomal recessive disorder characterized by the triad of achalasia, alacrimia and adrenal insufficiency. It is caused by the mutations of the AAAS gene located on chromosome 12q13. The c. Read More

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June 2018
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Maternal thyroid disorder in pregnancy and risk of cerebral palsy in the child: a population-based cohort study.

BMC Pediatr 2018 May 31;18(1):181. Epub 2018 May 31.

Section of Social Medicine, Department of Public Health, University of Copenhagen, Gothersgade 160, 1123, Copenhagen, Denmark.

Background: Cerebral palsy is the most frequent motor disability in childhood, but little is known about its etiology. It has been suggested that cerebral palsy risk may be increased by prenatal thyroid hormone disturbances. The objective of this study was to investigate whether maternal thyroid disorder is associated with increased risk of cerebral palsy. Read More

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Segmental Assessment of Trunk Control in infants from 4 to 9 months of age- a psychometric study.

BMC Pediatr 2018 May 31;18(1):182. Epub 2018 May 31.

Physiotherapy Department, Prince of Wales Hospital, Shatin, Hong Kong.

Background: Efficient trunk control is crucial in infant motor development when infants first learn how to move against gravity. Traditional assessments of trunk control commonly treat the trunk as one unit but the Segmental Assessment of Trunk Control (SATCo) assesses trunk control segment by segment. Good reliability and validity of the SATCo have been proved in children with neuro-disability but not yet validated in young infants. Read More

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Prevalence and risk factors of testicular microlithiasis in patients with hypospadias: a retrospective study.

BMC Pediatr 2018 May 29;18(1):179. Epub 2018 May 29.

Department of Renal and Genitourinary Surgery, Hokkaido University Graduate School of Medicine, North-15, West-7, Kita-Ku, Sapporo, 060-8638, Japan.

Background: It has been described that the incidence of testicular microlithiasis is high in several congenital disorders which may be associated with testicular impairment and infertility. Several reports have shown that a prepubertal or pubertal hormonal abnormality in the pituitary-gonadal axis was identified in some patients with hypospadias that is one of the most common disorders of sex development. However, exact prevalence or risk factors of testicular microlithiasis in patients with hypospadias have not reported so far. Read More

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Network meta-analysis: users' guide for pediatricians.

BMC Pediatr 2018 May 29;18(1):180. Epub 2018 May 29.

Department of Clinical Epidemiology & Biostatistics, McMaster University, Hamilton, ON, Canada.

Background: Network meta-analysis (NMA) is a powerful analytic tool that allows simultaneous comparison between several management/treatment alternatives even when direct comparisons of the alternatives (such as the case in which treatments are compared against placebo and have not been compared against each other) are unavailable. Though there are still a limited number of pediatric NMAs published, the rapid increase in NMAs in other areas suggests pediatricians will soon be frequently facing this new form of evidence summary.

Discussion: Evaluating the NMA evidence requires serial judgments on the creditability of the process of NMA conduct, and evidence quality assessment. Read More

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DTwP-HB-Hib: antibody persistence after a primary series, immune response and safety after a booster dose in children 18-24 months old.

BMC Pediatr 2018 May 28;18(1):177. Epub 2018 May 28.

Department of Child Health, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital, Jl. Diponegoro No 71, Jakarta, 10430, Indonesia.

Background: The new combination of DTwP-HB-Hib vaccines has been developed in Indonesia following World Health Organization (WHO) recommendation and integrated into national immunization program. The aims of the study were to measure 1) antibody persistence 12-18 months after a primary series, 2) immune response and safety after a booster dose of DTwP-HB-Hib.

Methods: This was a multi-center, open-labeled, prospective, interventional study. Read More

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Correlation between serum vitamin D level and neonatal indirect hyperbilirubinemia.

BMC Pediatr 2018 May 26;18(1):178. Epub 2018 May 26.

Department of Pediatrics, Qazvin University of Medical Sciences, Tehran, Iran.

Background: Considering the significant prevalence of Neonatal Indirect Hyperbilirubinemia (NIH) and its irreversible neurological complications, identifying the factors involved in the prevalence of neonatal jaundice is essential. The present study was conducted to determine the relationship between serum vitamin D levels and the prevalence of NIH in infants admitted to Qods Hospital of Qazvin in Iran in 2015-16.

Methods: In this case-control study, 30 term infants with NIH (the case group) were compared with 30 healthy, non- icteric, term infants (the control group) in terms of serum levels of 25-hydroxyvitamin D. Read More

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Psychometric properties and parental reported utility of the 19-item 'About My Child' (AMC-19) measure.

BMC Pediatr 2018 May 25;18(1):174. Epub 2018 May 25.

School of Rehabilitation Sciences, CanChild, McMaster University, Institute for Applied Health Sciences, 1200 Main Street West, Hamilton, ON, L8N 3Z5, Canada.

Background: 'About My Child' 19-item version (AMC-19) is a parent-report measure developed to assess the complexity of a child's life due to biological, psychological, social and environmental issues, that can be completed in approximately 5 min. AMC measures two dimensions of complexity: parental concerns and impact on the child. This paper examines the psychometric properties and parent-reported utility of the AMC-19 for children with disabilities or special health care needs. Read More

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Attitudes of pediatricians toward Children's consumption of ionic beverages.

BMC Pediatr 2018 May 25;18(1):176. Epub 2018 May 25.

Department of Pediatrics, Juntendo University Faculty of Medicine, Tokyo, Japan.

Background: The aim of our study was to clarify the attitudes of pediatricians toward children's consumption of ionic beverages.

Methods: A questionnaire survey of pediatric practitioners' attitudes toward the consumption of ionic beverages was administered to 537 doctors under 60 years of age who were members of the Japanese Pediatric Society.

Results: We received 215 valid responses from 182 board-certified pediatric specialists and 31 non-specialists. Read More

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A national estimate of the birth prevalence of congenital anomalies in India: systematic review and meta-analysis.

BMC Pediatr 2018 May 25;18(1):175. Epub 2018 May 25.

Interdisciplinary School of Health Sciences, Savitribai Phule Pune University, Pune, 411007, India.

Background: A quarter of all global neonatal deaths occur in India. Congenital anomalies constitute the fifth largest cause of neonatal mortality in the country, but national estimates of the prevalence of these conditions are lacking. The objective of the study was to derive an estimate of the birth prevalence of congenital anomalies in India. Read More

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Prevalence and determinants of essential newborn care practices in the Lawra District of Ghana.

BMC Pediatr 2018 May 24;18(1):173. Epub 2018 May 24.

University for Development Studies, School of Allied Health Sciences, P O Box, 1883, Tamale, Ghana.

Background: There was less than satisfactory progress, especially in sub-Saharan Africa, towards child and maternal mortality targets of Millennium Development Goals (MDGs) 4 and 5. The main aim of this study was to describe the prevalence and determinants of essential new newborn care practices in the Lawra District of Ghana.

Methods: A cross-sectional study was carried out in June 2014 on a sample of 422 lactating mothers and their children aged between 1 and 12 months. Read More

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Trends in the incidence and associated factors of late-onset sepsis associated with improved survival in extremely preterm infants born at 23-26 weeks' gestation: a retrospective study.

BMC Pediatr 2018 May 23;18(1):172. Epub 2018 May 23.

Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, 06351, Korea.

Background: To investigate the trends in the incidence and associated factors of late-onset sepsis (LOS) associated with improved survival in extremely preterm infants.

Methods: Medical records of 364 infants who were born at 23-26 weeks' gestation from 2000 to 2005 (period I, n = 124) and from 2006 to 2011 (period II, n = 240) were retrospectively reviewed. The infants were stratified into subgroups of 23-24 and 25-26 weeks' gestation within each period, and survival, LOS rate, and clinical characteristics were analyzed. Read More

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May 2018
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A case report of reversible generalized seizures in a patient with Waardenburg syndrome associated with a novel nonsense mutation in the penultimate exon of SOX10.

BMC Pediatr 2018 May 23;18(1):171. Epub 2018 May 23.

Department of Otolaryngology, National Center for Child Health and Development, Tokyo, Japan.

Background: Waardenburg syndrome type 1 (WS1) can be distinguished from Waardenburg syndrome type 2 (WS2) by the presence of dystopia canthorum. About 96% of WS1 are due to PAX3 mutations, and SOX10 mutations have been reported in 15% of WS2.

Case Presentation: This report describes a patient with WS1 who harbored a novel SOX10 nonsense mutation (c. Read More

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Residents' breastfeeding knowledge, comfort, practices, and perceptions: results of the Breastfeeding Resident Education Study (BRESt).

BMC Pediatr 2018 May 22;18(1):170. Epub 2018 May 22.

University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada.

Background: Physicians have a significant impact on new mothers' breastfeeding practices. However, physicians' breastfeeding knowledge is suboptimal. This knowledge deficit could be the result of limited breastfeeding education in residency. Read More

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May 2018
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Parental-reported allergic disorders and emergency department presentations for allergy in the first five years of life; a longitudinal birth cohort.

BMC Pediatr 2018 May 22;18(1):169. Epub 2018 May 22.

Menzies Health Institute Queensland, Griffith University, Nathan, QLD, Australia.

Background: To measure rates of parental-report of allergic disorders and ED presentations for allergic disorders in children, and to describe factors associated with either.

Methods: An existing cohort of 3404 children born between 2006 and 2011 (Environments for Healthy Living) with prospectively collected pre-natal, perinatal and follow-up data were linked to i) nationwide Medicare and pharmaceutical data and ii) Emergency Department (ED) data from four hospitals in Australia. Parental-reported allergy was assessed in those who returned follow-up questionnaires. Read More

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Stabilization of the obesity epidemic and increasing thinness in children in Caribbean Bonaire.

BMC Pediatr 2018 May 17;18(1):168. Epub 2018 May 17.

Department of Public and Occupational Health, Amsterdam Public Health Research Institute, VU Medical Center, Amsterdam, the Netherlands.

Background: In 2008, the prevalence of overweight and obesity among children in Bonaire was twice as high as the prevalence in northern Europe but comparable to that of other Caribbean islands and the United States. The aim of this study was to examine change in the body mass index status of children in Bonaire and report children's energy balance-related behaviours (EBRB) in 2015.

Methods: Two school-based cross sectional surveys of children age 4-14 years were conducted in 2008 and 2015. Read More

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Congenital Rhabdomyosarcoma: a different clinical presentation in two cases.

BMC Pediatr 2018 May 15;18(1):166. Epub 2018 May 15.

Department of Pediatric Hematology/Oncology, Bambino Gesù Children's Hospital, IRCCS, Piazza di Sant'Onofrio 4, 00165, Rome, Italy.

Background: Rhabdomyosarcoma (RMS), one of the most common soft tissue sarcomas of childhood, is very rare in the neonatal period (0.4-2% of cases). In order to gain a deeper understanding of this disease at such age, patient and tumor features, as well as treatment modality and outcome need to be reported. Read More

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Practice and outcomes of neonatal resuscitation for newborns with birth asphyxia at Kakamega County General Hospital, Kenya: a direct observation study.

BMC Pediatr 2018 May 15;18(1):167. Epub 2018 May 15.

Department of Nursing, Makerere University, School of Health Sciences, Kampala, Uganda.

Background: About three - quarters of all neonatal deaths occur during the first week of life, with over half of these occurring within the first 24 h after birth. The first minutes after birth are critical to reducing neonatal mortality. Successful neonatal resuscitation (NR) has the potential to prevent these perinatal mortalities related to birth asphyxia. Read More

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May 2018
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Parent perspectives on school food allergy policy.

BMC Pediatr 2018 May 12;18(1):164. Epub 2018 May 12.

Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

Background: Food allergy affects up to 8% of children in the U.S. There is minimal research to date on food allergy policies that are currently in place in schools and the opinions of parents of children with food allergy on the effectiveness of or need for these policies. Read More

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May 2018
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Leisure time physical activity in 9- to 11-year-old children born moderately preterm: a cohort study.

BMC Pediatr 2018 May 12;18(1):163. Epub 2018 May 12.

Perinatal Epidemiology Research Unit, Department of Paediatrics, Aarhus University Hospital, Skejby, Aarhus, Denmark.

Background: Physical activity is one of the best documented activities with impacts on health in children and adults. Children born preterm show reduced physical and psychosocial function compared to children born at term. This may influence their level of physical activity. Read More

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Clinical outcomes of interactive, intensive and individual (3i) play therapy for children with ASD: a two-year follow-up study.

BMC Pediatr 2018 May 12;18(1):165. Epub 2018 May 12.

Department of Child and Adolescent Psychiatry, Hôpital de la Pitie-Salpêtriere, University Pierre and Marie Curie, 75013, Paris, France.

Background: The outcomes of psycho-educational interventions for Autism Spectrum Disorders (ASDs) comorbid with severe to moderate intellectual disability (ID) are insufficiently documented. In this prospective study, we examined a developmental individual, interactive and intensive approach, called the '3i method', which is based on play therapy.

Methods: Twenty DSM-IV-TR ASD subjects (mean chronological age 63. Read More

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May 2018
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Patterns of early life body mass index and childhood overweight and obesity status at eight years of age.

BMC Pediatr 2018 May 11;18(1):161. Epub 2018 May 11.

Child and Family Research Institute, BC Children's and Women's Hospital, Vancouver, BC, Canada.

Background: Excess weight gain in infancy and childhood is associated with increased risk of subsequent obesity. Identifying patterns of infancy and childhood weight gain associated with subsequent obesity or overweight status could help identify children at highest risk. Thus, we examined patterns of infancy and early childhood BMI in relation to mid-childhood overweight and obesity status. Read More

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Augmentative and alternative communication in children with Down's syndrome: a systematic review.

BMC Pediatr 2018 May 11;18(1):160. Epub 2018 May 11.

Laboratório de Delineamento de Estudos e Escrita Científica, Departamento de Saúde da Coletividade, Faculdade de Medicina do ABC (FMABC), Rua Fagundes Varela, 121. Vila Príncipe de Gales, 09060510, Santo André, SP, Brasil.

Background: The use of technology to assist in the communication, socialization, language, and motor skills of children with Down's syndrome (DS) is required. The aim of this study was to analyse research findings regarding the different instruments of 'augmentative and alternative communication' used in children with Down's syndrome.

Methods: This is a systematic review of published articles available on PubMed, Web of Science, PsycInfo, and BVS using the following descriptors: assistive technology AND syndrome, assistive technology AND down syndrome, down syndrome AND augmentative and alternative communication. Read More

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Obliterative cholangiopathy in acquired cystic biliary atresia type III after cyst perforation: a case report.

BMC Pediatr 2018 May 11;18(1):158. Epub 2018 May 11.

Department of Pediatric Surgery, Nihon University, School of Medicine, 30-1 Ooyaguchi-kamicho, Itabashi-ku, Tokyo, 173-8610, Japan.

Background: In biliary atresia, the disease process of obliterative cholangiopathy may begin in the perinatal period; however, no chronological evidence exists on how the cholangiopathy progresses to biliary obliteration. This is the first acquired case with the final diagnosis of type III cystic biliary atresia with an extrahepatic biliary cyst which showed the progression of obliterative cholangiopathy in chronological order after birth.

Case Presentation: An 81-day-old girl presented with acute abdominal distress due to bilious peritonitis caused by biliary cyst perforation, for which she underwent emergency biliary drainage. Read More

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Meconium peritonitis due to fetal appendiceal perforation: two case reports and a brief review of the literature.

BMC Pediatr 2018 May 11;18(1):162. Epub 2018 May 11.

Department of Pediatric Surgery, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, No 1665, Kongjiang Road, Shanghai, 200092, People's Republic of China.

Background: Meconium peritonitis is an infrequent congenital disease usually caused by perforation of the fetal digestive tract. Meconium peritonitis resulting from intrauterine appendiceal perforation has been rarely reported and is often overlooked during pregnancy. We herein report two cases of fetal appendiceal perforation. Read More

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May 2018
1 Read

Henoch-Schönlein purpura with acute pancreatitis: analysis of 13 cases.

BMC Pediatr 2018 May 11;18(1):159. Epub 2018 May 11.

Department of Pediatrics, First Affiliated Hospital of Anhui Medical University, 19th Floor of Medicine and Medical Tech Building, 218 Jixi Road, Hefei, 230022, Anhui, China.

Background: Henoch-Schönlein purpura is a common small vessel vasculitis in children. Acute pancreatitis rarely presents as a complication of Henoch-Schönlein purpura and has not been well characterized.

Methods: We retrospectively reviewed 13 cases of Henoch-Schönlein purpura with acute pancreatitis among 3212 patients who attended our hospital between January 2003 and June 2016 and analyzed their clinical characteristics, laboratory findings, imaging findings, treatment and overall prognosis. Read More

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Hemorrhagic bullous lesions in Henoch-Schönlein purpura: a case report and review of the literature.

BMC Pediatr 2018 May 10;18(1):157. Epub 2018 May 10.

Division of Pediatric Allergy, Immunology and Rheumatology, Department of Pediatrics, Kaohsiung Veterans General Hospital, No. 386, Dazhong 1st Road, Zuoying District, Kaohsiung City, 813, Taiwan.

Background: Henoch-Schönlein purpura (HSP) is a common vasculitis in childhood characterized by purpura, arthritis, abdominal pain and renal involvement. However, bullous HSP is a rare cutaneous manifestation, and a few cases have been reported.

Case Presentation: Herein, we report a 15-year-old male with bullous HSP who presented with severe abdominal pain and hemorrhagic bullous lesions over his lower extremities. Read More

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May 2018
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Muscle and tendon morphology alterations in children and adolescents with mild forms of spastic cerebral palsy.

BMC Pediatr 2018 May 9;18(1):156. Epub 2018 May 9.

Department of Paediatric Surgery, Medical University of Graz, Auenbruggerplatz 34, 8036, Graz, Austria.

Background: Early detection of changes at the muscular level before a contracture develops is important to gain knowledge about the development of deformities in individuals with spasticity. However, little information is available about muscle morphology in children with spastic diplegic cerebral palsy (CP) without contracture or equinus gait. Therefore, the aim of this study was to compare the gastrocnemius medialis (GM) and Achilles tendon architecture of children and adolescents with spastic CP without contracture or equinus gait to that of typically developing (TD) children. Read More

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Effect of increased enteral protein intake on plasma and urinary urea concentrations in preterm infants born at < 32 weeks gestation and < 1500 g birth weight enrolled in a randomized controlled trial - a secondary analysis.

BMC Pediatr 2018 May 8;18(1):154. Epub 2018 May 8.

Department of Neonatology, University Children's Hospital, Tübingen University Hospital, Calwerstr. 7, Tübingen, Germany.

Background: Feeding breast milk is associated with reduced morbidity and mortality, as well as improved neurodevelopmental outcome but does not meet the high nutritional requirements of preterm infants. Both plasma and urinary urea concentrations represent amino acid oxidation and low concentrations may indicate insufficient protein supply. This study assesses the effect of different levels of enteral protein on plasma and urinary urea concentrations and determines if the urinary urea-creatinine ratio provides reliable information about the protein status of preterm infants. Read More

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May 2018
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Impact of umbilical cord milking and pasteurized donor human milk on necrotizing enterocolitis: a retrospective review.

BMC Pediatr 2018 May 8;18(1):155. Epub 2018 May 8.

Division of Neonatology, University of Utah School of Medicine, 295 Chipeta Way, Salt Lake City, UT, 84108, USA.

Background: Necrotizing enterocolitis (NEC) is a serious complication of prematurity. Our objective was to evaluate the impact of an umbilical cord milking protocol (UCM) and pasteurized donor human milk (PDHM) on NEC rates in infants less than 30 weeks gestational age from January 1, 2010 to September 30, 2016. We hypothesized an incremental decrease in NEC after each intervention. Read More

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Inhaled corticosteroids in ventilated preterm neonates: a non-randomized dose-ranging study.

BMC Pediatr 2018 May 7;18(1):153. Epub 2018 May 7.

Department of Paediatrics, University of Toronto, Toronto, ON, Canada.

Background: Inhaled corticosteroids (ICS) offer targeted treatment for bronchopulmonary dysplasia (BPD) with minimal systemic effects compared to systemic steroids. However, dosing of ICS in the management of infants at high-risk of developing BPD is not well established. The objective of this study was to determine an effective dose of ICS for the treatment of ventilator-dependent infants to facilitate extubation or reduce fractional inspired oxygen concentration. Read More

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Child abuse and neglect in the Jaffna district of Sri Lanka - a study on knowledge attitude practices and behavior of health care professionals.

BMC Pediatr 2018 May 5;18(1):152. Epub 2018 May 5.

Department of Paediatrics, University of Jaffna, PO Box: 57, Adiyapatham Raod, Jaffna, Sri Lanka.

Background: Victims and perpetrators of child abuse do not typically self-report to child protection services, therefore responsibility of detection and reporting falls on the others. Knowledge on child protection is essential for the first contact person and such information is sparse in research literature originally coming from Sri Lanka. Anecdotally, several cases of child abuse have been missed out at the first contact level. Read More

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