1,651 results match your criteria BMC Ophthalmology[Journal]


Intravitreal dexamethasone implant for central retinal vein occlusion without macular edema.

BMC Ophthalmol 2019 Apr 17;19(1):92. Epub 2019 Apr 17.

Department of Ophthalmology, Gangnam Severance Hospital, Yonsei University College of Medicine, 211, Eonjuro, Gangnam-gu, Seoul, 06273, South Korea.

Background: To evaluate the efficacy of an intravitreal dexamethasone (IVD) implant (Ozurdex®) for the treatment of central retinal vein occlusion (CRVO) without macular edema (ME).

Methods: A retrospective cohort study was designed, and 20 eyes of 20 patients diagnosed with non-ischemic CRVO without ME were included. A total of 10 CRVO eyes were observed without treatment, and another 10 CRVO eyes received a single IVD injection at baseline. Read More

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https://bmcophthalmol.biomedcentral.com/articles/10.1186/s12
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http://dx.doi.org/10.1186/s12886-019-1097-yDOI Listing
April 2019
2 Reads

Incidence of retinopathy of prematurity type 1 and type 2 in a regional Hospital of Social Security in the state of Queretaro, Mexico (2017-2018).

BMC Ophthalmol 2019 Apr 15;19(1):91. Epub 2019 Apr 15.

Instituto Mexicano de Oftalmología IAP, Circuito de Estadio de Corregidora, sin número, Santiago de Querétaro, Querétaro, Mexico.

Background: Retinopathy of prematurity (ROP), the primary cause of blindness in children, is a potential complication for 7.7% of live births in Mexico. Given that less than one-third of all neonatal intensive care units follow Mexican National ROP guidelines, there have been few reports regarding the incidences of types 1 and 2 ROP. Read More

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http://dx.doi.org/10.1186/s12886-019-1095-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466710PMC

Simulation training in vitreoretinal surgery: a systematic review.

BMC Ophthalmol 2019 Apr 11;19(1):90. Epub 2019 Apr 11.

Department of Ophthalmology, Odense University Hospital, J.B. Winsløws Vej 4, DK-5000, Odense C, Denmark.

Background: The purpose of this study was to perform a systematic review of the current literature on simulator-based training in vitreoretinal surgery (VRS). We examined the results regarding simulated VRS and provided an overview of how the current results may be employed in VRS training. Lastly, we evaluated the quality of these results. Read More

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http://dx.doi.org/10.1186/s12886-019-1098-xDOI Listing

Visual and optical quality outcomes of SMILE and FS-LASIK for myopia in the very early phase after surgery.

BMC Ophthalmol 2019 Apr 8;19(1):88. Epub 2019 Apr 8.

Department of Ophthalmology, Daping Hospital of Army Medical University of PLA, No. 10 Changjiangzhi Road, Yuzhong District, Chongqing, 400042, China.

Background: Small incision lenticule extraction (SMILE) and femtosecond laser-assisted in situ keratomileusis (FS-LASIK) are frequently used to treat myopia. However, little is known about the impact on recovery of these approaches in the very early postsurgical phase (within 24 h).

Methods: To compare the efficacy of these two procedures for the treatment of myopia in the early phase after surgery, differences in visual acuity, OSI (objective scattering index), cutoff for modulation transfer function (MTF), and SR (Strehl ratio) between SMILE and FS-LASIK were evaluated at 0, 2, 4 and 24 h postoperatively using two-way analysis of variance (ANOVA). Read More

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http://dx.doi.org/10.1186/s12886-019-1096-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454732PMC

Diagnostic test accuracy of diabetic retinopathy screening by physician graders using a hand-held non-mydriatic retinal camera at a tertiary level medical clinic.

BMC Ophthalmol 2019 Apr 8;19(1):89. Epub 2019 Apr 8.

Public Health for Eye Care and Disability, International Centre for Eye Health, Clinical Research Department, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.

Background: The evidence on diagnostic test accuracy (DTA) of diabetic retinopathy (DR) screening utilising photographic studies by non-ophthalmologist personnel in low and middle-income country (LMIC) settings is scarce. We aimed to assess DTA of DR screening using a nonmydriatic hand-held digital camera by trained general physicians in a non-ophthalmic setting.

Methods: This study is a validation of a screening intervention. Read More

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http://dx.doi.org/10.1186/s12886-019-1092-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454614PMC
April 2019
1 Read

Adjunctive dexamethasone implant in patients with atopic dermatitis and retinal detachment undergoing vitrectomy and silicone oil tamponade: an interventional case series.

BMC Ophthalmol 2019 Apr 3;19(1):86. Epub 2019 Apr 3.

Department of Ophthalmology, University of Ulsan, College of Medicine, Asan Medical Center, 88, Olympic-ro 43-Gil, Songpa-gu, Seoul, 05505, Korea.

Background: To report the clinical course and outcomes of adjunctive dexamethasone implants in patients with atopic dermatitis (AD) and retinal detachment (RD) undergoing vitrectomy and silicone oil tamponade.

Methods: This retrospective, interventional case series included AD patients with RD and various degrees of proliferative vitreoretinopathy (PVR) who were scheduled to undergo vitrectomy. Following total vitrectomy and retinopexy, silicone oil tamponade was performed. Read More

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http://dx.doi.org/10.1186/s12886-019-1094-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448232PMC
April 2019
2 Reads
1.075 Impact Factor

Epidemiology and clinical features of viral anterior uveitis in southern Taiwan-diagnosis with polymerase chain reaction.

BMC Ophthalmol 2019 Apr 3;19(1):87. Epub 2019 Apr 3.

Department of Ophthalmology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, No.123, Dapi Rd., Niaosong Dist, Kaohsiung, 833, Taiwan.

Background: To report the epidemiology and clinical features of viral anterior uveitis in patients in southern Taiwan.

Methods: A retrospective, case series study. HLA-B27 negative anterior uveitis patients with increased intraocular pressure or corneal edema seen at Kaohsiung Chang Gung Memorial Hospital from January 1, 2007 to January 31, 2018 had their aqueous sent for polymerase chain reaction analysis. Read More

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http://dx.doi.org/10.1186/s12886-019-1093-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448235PMC
April 2019
2 Reads

Individualized penetrating keratoplasty using edge-trimmed glycerol-preserved donor corneas for perforated corneal ulcers.

BMC Ophthalmol 2019 Apr 2;19(1):85. Epub 2019 Apr 2.

Department of Ophthalmology, Tongji Hospital, Tongji University School of Medicine, 389 Xincun Road, Shanghai, 200065, China.

Purpose: To report a surgical technique and the surgical outcomes of individualized penetrating keratoplasty (PK) using edge-trimmed glycerol-preserved donor corneas for perforated corneal ulcers.

Methods: Fourteen perforated eyes from 14 patients who underwent individualized PK using edge-trimmed glycerol-preserved donor corneas, were included in the retrospective study. The perforations were mainly 1-2 mm in size except for one that was 2. Read More

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http://dx.doi.org/10.1186/s12886-019-1091-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444435PMC
April 2019
1 Read

A real-world study of effectiveness of intravitreal bevacizumab and ranibizumab injection for treating retinal diseases in Thailand.

BMC Ophthalmol 2019 Mar 29;19(1):82. Epub 2019 Mar 29.

Health Intervention and Technology Assessment Program (HITAP), Ministry of Public Health, Nonthaburi, Thailand.

Background: To evaluate the effectiveness of intravitreal bevacizumab (IVB) and intravitreal ranibizumab (IVR) in actual practice for treating patients with retinal diseases in Thailand.

Methods: A prospective, multi-centre, observational study was conducted among eight hospitals in their ophthalmology outpatient departments. Participants consisted of patients who had previously not received any IVB or IVR treatment between 2013 and 2014. Read More

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http://dx.doi.org/10.1186/s12886-019-1086-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439979PMC
March 2019
2 Reads

The relationship between foveal outer nuclear layer thickness in the active and resolved phases of central serous chorioretinopathy treated with half-dose photodynamic therapy.

BMC Ophthalmol 2019 Mar 29;19(1):84. Epub 2019 Mar 29.

Department of Ophthalmology, Eye & Ear Nose Throat Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, People's Republic of China.

Background: To investigate the relationship between the foveal outer nuclear layer (ONL) thickness in the active and resolved phases of central serous chorioretinopathy (CSC), and its possible association with optical coherence tomography (OCT) parameters.

Methods: The medical records of CSC patients treated with half-dose photodynamic therapy (PDT) between August 2011 and October 2017 were reviewed. The difference between the foveal ONL thickness at 12 m after half-dose PDT and that before half-dose PDT was analyzed, and its association with OCT parameters was assessed using generalized linear models. Read More

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http://dx.doi.org/10.1186/s12886-019-1089-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440016PMC
March 2019
2 Reads
1.075 Impact Factor

Bilateral granulomatous panuveitis in two patients with T-cell type of chronic active Epstein-Barr virus infection.

BMC Ophthalmol 2019 Mar 29;19(1):83. Epub 2019 Mar 29.

Department of Ophthalmology & Visual Science Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), 1-5-45, Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan.

Background: To report 2 cases of bilateral granulomatous panuveitis accompanied by chronic active Epstein-Barr virus infection (CAEBV).

Case Presentation: Case 1 was a 38-year-old man who had a history of bilateral mild panuveitis who was diagnosed with CAEBV. Fifteen months later, a severe bilateral granulomatous panuveitis developed. Read More

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http://dx.doi.org/10.1186/s12886-019-1090-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440096PMC
March 2019
2 Reads

Comparative study of wave-front aberration and corneal Asphericity after SMILE and LASEK for myopia: a short and long term study.

BMC Ophthalmol 2019 Mar 20;19(1):80. Epub 2019 Mar 20.

Department of Ophthalmology, Eye and ENT Hospital, Fudan University, No. 83 Fenyang Road, Shanghai, 200031, China.

Background: The study compares the wave-front aberration and corneal asphericity from multiple perspectives after Small Incision Lenticule Extraction and Laser-assisted Subepithelial Keratomileusis for mild to moderate myopia in a short and long time period.

Methods: This prospective and comparative study included 32 eyes in the SMILE group, with a mean spherical equivalent (SE) of - 4.1 ± 0. Read More

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http://dx.doi.org/10.1186/s12886-019-1084-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425702PMC

Evaluation of eye-related parameters and adverse events of rigid gas permeable contact lens and spectacles correction in infants with monocular aphakia after congenital cataract surgery: a retrospective clinical study.

BMC Ophthalmol 2019 Mar 20;19(1):81. Epub 2019 Mar 20.

Department of Ophthalmology in XinHua hospital, Shanghai Jiao Tong University School of Medicine, No.1665 Kongjiang road , Yangpu District, Shanghai, China.

Background: Congenital cataract is currently one of the leading blindness-causing eye diseases in children. Surgical treatment only opens the visual pathway for children. The postoperative recovery of visual function is also dependent on effective optical correction and visual function training. Read More

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http://dx.doi.org/10.1186/s12886-019-1088-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425554PMC
March 2019
1 Read

Cyclic stretch induced oxidative stress by mitochondrial and NADPH oxidase in retinal pigment epithelial cells.

BMC Ophthalmol 2019 Mar 18;19(1):79. Epub 2019 Mar 18.

Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University; Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing, 100730, China.

Background: Vitreomacular adhesion (VMA) has been reported to associated with age-related macular degeneration (AMD). Understanding the mechanisms underlying cyclic stretch induced in retinal pigment epithelial cells (RPE) may be important for the treatment of VMA-related AMD.

Method: Cyclic stretch (1HZ, 20% elongation) was applied to cultured ARPE-19 cells for 15 min, 2 h, 6 h, 12 h, 24 h by flexcell FX-5000 Tension system. Read More

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https://bmcophthalmol.biomedcentral.com/articles/10.1186/s12
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http://dx.doi.org/10.1186/s12886-019-1087-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421648PMC
March 2019
5 Reads

Performance of femtosecond laser-assisted cataract surgery in Chinese patients with cataract: a prospective, multicenter, registry study.

BMC Ophthalmol 2019 Mar 14;19(1):77. Epub 2019 Mar 14.

Eye Center, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

Background: This study aimed to investigate the completion rate, visual performance, and adverse outcomes of femtosecond laser-assisted cataract surgery (FLACS) in Chinese patients.

Methods: This is a prospective, single-arm, multicenter registry study of 19 cataract surgery clinics in China. Chinese patients with cataract who underwent FLACS using the Alcon LenSx® laser system in single eye (n = 1140) or both eyes (n = 201) were enrolled and data were collected between March 2015 and August 2016. Read More

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http://dx.doi.org/10.1186/s12886-019-1079-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417229PMC
March 2019
1 Read

Objective vision screening using PlusoptiX for children aged 3-11 years in rural Turkey.

BMC Ophthalmol 2019 Mar 12;19(1):73. Epub 2019 Mar 12.

Department of Ophthalmology, Faculty of Medicine, Zonguldak Bulent Ecevit University, Esenkoy-Kozlu, 67600, Zonguldak, Turkey.

Background: This population based cross sectional study was conducted to detect amblyopia risk factors and myopia in a rural district of Northwestern Turkey by using PlusoptiX S12R (Photoscreener PlusoptiX Inc., Nuremberg, Germany).

Methods: Children from 38 rural schools in Caycuma district of Zonguldak Turkey underwent vision screening in their school using PlusoptiX S12 photoscreener. Read More

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http://dx.doi.org/10.1186/s12886-019-1080-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419461PMC

Comparison of postoperative visual performance between bifocal and trifocal intraocular Lens based on randomized controlled trails: a meta-analysis.

BMC Ophthalmol 2019 Mar 14;19(1):78. Epub 2019 Mar 14.

Beijing Institute of Ophthalmology, Beijing Tongren Eye CenterBeijing Tongren Hospital of Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing, China.

Background: To compare the clinical performance of bifocal and trifocal intraocular lenses (IOLs) in cataract surgery, a meta-analysis on randomized controlled trials was conducted.

Methods: A comprehensive literature retrieval of PubMed, Science Direct and EMBASE was performed in this systematic review. Clinical outcomes included visual acuity (VA), contrast sensitivity (CS), spectacle independence, postoperative refraction and surgical satisfaction. Read More

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http://dx.doi.org/10.1186/s12886-019-1078-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419463PMC
March 2019
1.075 Impact Factor

Visual implications of digital device usage in school children: a cross-sectional study.

BMC Ophthalmol 2019 Mar 12;19(1):76. Epub 2019 Mar 12.

Department of Ophthalmology, Government Medical College and Hospital, Sector 32, Chandigarh, India.

Purpose: To evaluate the use of digital devices, reading habits and the prevalence of eyestrain among urban Indian school children, aged 11-17 years.

Methods: The study included 576 adolescents attending urban schools who were surveyed regarding their electronic device usage. Additional information on the factors that may have an effect on ocular symptoms was collected. Read More

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http://dx.doi.org/10.1186/s12886-019-1082-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417240PMC
March 2019
1.075 Impact Factor

Efficacy and safety of Ex-PRESS® mini shunt surgery versus trabeculectomy for neovascular glaucoma: a retrospective comparative study.

BMC Ophthalmol 2019 Mar 12;19(1):75. Epub 2019 Mar 12.

Department of Ophthalmology, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto, 860-8556, Japan.

Background: The objective of this study is to evaluate and compare the short-term efficacy and safety of Ex-PRESS® mini shunt surgery and trabeculectomy for neovascular glaucoma (NVG).

Methods: Patients with NVG who underwent Ex-PRESS® mini shunt surgery or trabeculectomy as a primary glaucoma surgery between March 2013 and October 2015 were included in the study, and their medical charts were retrospectively reviewed. The Ex-PRESS® and trabeculectomy groups included 14 eyes and 30 eyes, respectively. Read More

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http://dx.doi.org/10.1186/s12886-019-1083-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416865PMC
March 2019
2 Reads

Delayed-onset interface fluid syndrome after LASIK following phacotrabeculectomy.

BMC Ophthalmol 2019 Mar 12;19(1):74. Epub 2019 Mar 12.

Department of Ophthalmology, Seoul National University Bundang Hospital, 300, Gumi-dong, Bundang-gu, Seongnam, Gyeonggi-do, 13620, South Korea.

Background: Interface fluid syndrome (IFS) is an unusual complication after laser-assisted in-situ keratomileusis (LASIK). We report the first case of IFS after uncomplicated phacotrabeculectomy in a patient who had undergone LASIK 10 years previously. This case emphasizes the importance of intraocular pressure (IOP) interpretation in eyes that have undergone LASIK. Read More

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http://dx.doi.org/10.1186/s12886-019-1077-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417165PMC

Effect of the retention ring-assisted continuous application of riboflavin in pulsed-light accelerated corneal collagen cross-linking on the progression of keratoconus.

BMC Ophthalmol 2019 Mar 11;19(1):72. Epub 2019 Mar 11.

Department of Ophthalmology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 110-744, South Korea.

Background: To investigate the efficacy and safety of the retention ring-assisted continuous application of 0.1% riboflavin in pulsed-light accelerated corneal collagen cross-linking on the progression of keratoconus.

Methods: The medical records of 20 eyes of 18 patients with progressive keratoconus who received collagen cross-linking at Seoul National University Hospital were retrospectively reviewed. Read More

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http://dx.doi.org/10.1186/s12886-019-1085-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417158PMC

Correction to: development of a core outcome set for amblyopia, strabismus and ocular motility disorders: a review to identify outcome measures.

BMC Ophthalmol 2019 03 11;19(1):71. Epub 2019 Mar 11.

Department of Health Services Research, University of Liverpool, Waterhouse Building Block B, 2nd Floor, 1-3 Brownlow Street, L69 3GL, Liverpool, UK.

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http://dx.doi.org/10.1186/s12886-019-1073-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410504PMC
March 2019
2 Reads

Effects of concentration of amyloid β (Aβ) on viability of cultured retinal pigment epithelial cells.

BMC Ophthalmol 2019 Mar 8;19(1):70. Epub 2019 Mar 8.

Department of Ophthalmology, Nara Medical University, 840 Shijo-cho, Kashihara, 634-8522, Japan.

Background: Amyloid beta (Aβ) is a constituent of drusen that is a common sign of age-related macular degeneration (AMD). The purpose of this study was to investigate the effect of Aβ on human retinal pigment epithelial (RPE) cells in culture.

Methods: Cells from a human RPE cell line (ARPE-19) were exposed to 0 to 25 μM of Aβ 1-40 for 48 h, and the number of living cells was determined by WST-8 cleavage. Read More

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http://dx.doi.org/10.1186/s12886-019-1076-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408759PMC

Acute emotional stress as a trigger for intraocular pressure elevation in Glaucoma.

BMC Ophthalmol 2019 Mar 8;19(1):69. Epub 2019 Mar 8.

Glaucoma Research Center, Montchoisi Clinic, Swiss Visio Network, Lausanne, Switzerland.

Background: Stress-induced activation of the sympathetic nervous system leads to a cascade of metabolic reactions. Emotional stress is a more specific form of stress in which the stressor is a psychological response to a situation subjectively perceived as traumatic. Stress hormones can have a wide range of effects on the body, however, it is still unclear if and how it can affect ophthalmic physiology. Read More

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https://bmcophthalmol.biomedcentral.com/articles/10.1186/s12
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http://dx.doi.org/10.1186/s12886-019-1075-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408777PMC
March 2019
5 Reads

Choroidal neovascularization emerged right from the focal choroidal excavation in eyes with central serous chorioretinopathy post half-dose photodynamic therapy: a case report.

BMC Ophthalmol 2019 Mar 8;19(1):68. Epub 2019 Mar 8.

Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, 200032, China.

Background: Focal choroidal excavation (FCE) is a common concurrent disease with central serous chorioretinopathy (CSC) and choroidal neovascularization (CNV). Photodynamic therapy (PDT) was able to cease the course of CSC with efficacy and safety. To retrospectively observed and followed up a special course in eyes with CSC and concurrent FCE treated by a half-dose of PDT. Read More

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http://dx.doi.org/10.1186/s12886-019-1081-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408815PMC
March 2019
1 Read
1.075 Impact Factor

Evaluation of the ocular surface characteristics and Demodex infestation in paediatric and adult blepharokeratoconjunctivitis.

BMC Ophthalmol 2019 Mar 7;19(1):67. Epub 2019 Mar 7.

Department of Ophthalmology, Eye & ENT Hospital, Fudan University, 83 Fenyang Road, Xuhui District, Shanghai, 200031, China.

Background: To evaluate the ocular surface characteristics and the infestation of Demodex in Chinese paediatric and adult blepharokeratoconjunctivitis (BKC).

Methods: Fifty consecutive patients with BKC and 50 age- and sex-matched healthy subjects were enrolled. Lid margin characteristics and corneal disorders were evaluated under slit-lamp illumination. Read More

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http://dx.doi.org/10.1186/s12886-019-1074-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407278PMC
March 2019
2 Reads

Refractive corneal inlay for presbyopia in emmetropic patients in Asia: 6-month clinical outcomes.

BMC Ophthalmol 2019 Mar 5;19(1):66. Epub 2019 Mar 5.

Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, #81 Irwon-ro, Gangnam-gu, Seoul, 06351, South Korea.

Background: To evaluate the 6-month clinical outcomes of Flexivue Microlens refractive corneal inlay in emmetropic patients in Asia for the surgical compensation of presbyopia.

Methods: In this retrospective study, corneal inlay implantation was done using a femtosecond laser. The follow-up period was 6 months. Read More

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http://dx.doi.org/10.1186/s12886-019-1069-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399973PMC
March 2019
2 Reads

The effect of phacoemulsification plus goniosynechialysis in acute and chronic angle closure patients with extensive goniosynechiae.

BMC Ophthalmol 2019 Mar 4;19(1):65. Epub 2019 Mar 4.

Department of Ophthalmology, Peking University First Hospital, 8 Xi Shi Ku Street, Xi Cheng District, Beijing, 100034, People's Republic of China.

Background: Patients with primary angle closure/glaucoma (PAC/PACG) with extensive peripheral anterior synechiae (PAS), and coexisting cataract, increasingly have been treated with phacoemulsification combined with goniosynechialysis (Phaco-GSL). Since the mechanisms of acute and chronic PAC/PACG may differ, the treatment effect of this procedure also may differ. The purpose of this study was to establish whether there was a difference in the therapeutic effect of Phaco-GSL on these two groups of patients, the results of which could provide clinical evidence for improvement in treatment protocols for patients with PAC/PACG and extensive PAS. Read More

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http://dx.doi.org/10.1186/s12886-019-1070-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399882PMC
March 2019
3 Reads

Correction to: P66Shc expression in diabetic rat retina.

BMC Ophthalmol 2019 03 1;19(1):64. Epub 2019 Mar 1.

Department of Ophthalmology, The First Affiliated Hospital of Soochow, University, Suzhou, 215006, China.

Following publication of the original article. Read More

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http://dx.doi.org/10.1186/s12886-019-1071-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396470PMC
March 2019
3 Reads

Evaluation of choroidal parameters in eyes at the first onset of acute anterior uveitis.

BMC Ophthalmol 2019 Feb 28;19(1):63. Epub 2019 Feb 28.

First Department of Ophthalmology, Pomeranian Medical University in Szczecin, Al. Powstańców Wielkopolskich 72, 70-111, Szczecin, Poland.

Background: Little is known about choroidal involvement in anterior uveitis. The aim of our study was to evaluate changes in choroidal thickness and volume in eyes with acute anterior uveitis (AAU) using enhanced depth imaging-optical coherence tomography (EDI-OCT) at baseline and after treatment, which were compared with healthy fellow eyes.

Methods: For the study, 35 individuals with unilateral acute AAU at the first onset were enrolled. Read More

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https://bmcophthalmol.biomedcentral.com/articles/10.1186/s12
Publisher Site
http://dx.doi.org/10.1186/s12886-019-1072-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396533PMC
February 2019
5 Reads

Ocular toxicity of intravitreal melphalan for retinoblastoma in Chinese patients.

BMC Ophthalmol 2019 Feb 26;19(1):61. Epub 2019 Feb 26.

Department of Ophthalmology, Eye, Ear, Nose, and Throat Hospital of Fudan University, Shanghai Key Laboratory of Visual Impairmentand Restoration of Fudan University, Shanghai, 200031, China.

Background: To evaluate the efficacy, complications, and clinical characteristics, including the ocular toxicity, of intravitreal melphalan(IVM) treatment for vitreous seeding in Chinese retinoblastoma patients.

Methods: This was a retrospective, non-comparative analysis including 30 consecutive eyes of 23 patients with viable persistent or recurrent vitreous seeding following retinoblastoma treatment. All of the eyes received IVM injections (20-33 μg). Read More

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http://dx.doi.org/10.1186/s12886-019-1059-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390546PMC
February 2019
1 Read

Ranibizumab injection and laser photocoagulation to treat type 1 retinopathy of prematurity after 40 weeks post menstrual age: a retrospective case series study.

BMC Ophthalmol 2019 Feb 26;19(1):60. Epub 2019 Feb 26.

Department of Ophthalmology, Xinhua Hospital, Medical School, Shanghai Jiao Tong University, 1665 Kong Jiang Road, Shanghai, 200092, China.

Background: Type 1 retinopathy of prematurity (ROP) is occasionally observed in preterm infants after the postmenstrual age (PMA) of 40 weeks; however, evidence-based treatment guidelines are largely lacking. In this study, we report the clinical characteristics of preterm infants with type 1 ROP at PMA of > 40 weeks and compare the treatment outcomes of intravitreal ranibizumab (IVR) and laser therapy.

Methods: Twenty-seven eyes of 14 infants, primarily treated for type 1 ROP after 40 weeks PMA by IVR (17 eyes in 9 infants) or by laser photocoagulation (10 eyes in 5 infants) were included in this retrospective analysis. Read More

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http://dx.doi.org/10.1186/s12886-019-1067-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390561PMC
February 2019
1 Read
1.075 Impact Factor

The effect of diluting povidone-iodine on bacterial growth associated with speech.

BMC Ophthalmol 2019 Feb 26;19(1):62. Epub 2019 Feb 26.

Centre For Eye Research Australia, The Royal Victorian Eye and Ear Hospital, University of Melbourne, 32 Gisborne Street, East Melbourne, Victoria, 3002, Australia.

Background: Povidone-Iodine (PI) may be diluted when used as an antiseptic prior to an intravitreal injection in an attempt to decrease patient discomfort. This study aims to investigate the effect of diluting povidone-iodine (PI) on bacterial growth from bacterial droplet dispersal associated with speech.

Methods: Participants read a standardised script for 5 min over a blood agar plate positioned at 20 cm in a simulated position of an intravitreal injection procedure. Read More

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http://dx.doi.org/10.1186/s12886-019-1066-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390624PMC
February 2019
2 Reads

The effects of different shapes of capsulorrhexis on postoperative refractive outcomes and the effective position of the intraocular lens in cataract surgery.

BMC Ophthalmol 2019 Feb 21;19(1):59. Epub 2019 Feb 21.

Department of Ophthalmology, the Fourth Affiliated Hospital of China Medical University, Eye Hospital of China Medical University, the Key Lenticular Laboratory of Liaoning Province, Shenyang, 110005, China.

Background: To evaluate the effects of anterior capsular opening size on deviation from predicted refraction and the effective position of the intraocular lens (ELP) in cataract surgery.

Methods: Nonrandomized clinical trial. Eighty patients (80 eyes) with simple age-related cataracts were treated from May 2018 to September 2018 at the Fourth Affiliated Hospital of China Medical University. Read More

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http://dx.doi.org/10.1186/s12886-019-1068-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385455PMC
February 2019
3 Reads

Convergence insufficiency and accommodative insufficiency in children.

BMC Ophthalmol 2019 Feb 21;19(1):58. Epub 2019 Feb 21.

Departamento de Ciências Sociais e Humanas, Universidade da Beira Interior, Covilhã, Portugal.

Purpose: Convergence and accommodative insufficiency represent the main cause of complaints during close visual work and can reduce visual performance and comfort. Knowing their prevalence among schoolchildren is fundamental to define strategies for action. The purpose of this study was to estimate the frequency of these conditions in children in 5th and 6th school years in inland Portugal and to assess the impact that each visual condition has on their quality of life, based on the level of visual symptoms. Read More

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https://bmcophthalmol.biomedcentral.com/articles/10.1186/s12
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http://dx.doi.org/10.1186/s12886-019-1061-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385397PMC
February 2019
6 Reads

Modeling and simulation of phototransduction cascade in vertebrate rod photoreceptors.

BMC Ophthalmol 2019 Feb 20;19(1):55. Epub 2019 Feb 20.

Ministry of Education, Key Laboratory of Advanced Process Control for Light Industry, Jiangnan University, Wuxi, 214122, China.

Background: The activation of phototransduction cascade in rod photoreceptors has been well studied in literature, but there is a lack of a mature kinetic model structure covering both the activation and inactivation processes.

Methods: In this work, a kinetic model structure is developed to describe the major activation and inactivation processes in vertebrate rod photoreceptors with the electroretinogram (ERG) as output. Simulation was performed to validate developed model structure. Read More

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http://dx.doi.org/10.1186/s12886-019-1048-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381673PMC
February 2019

Decreased retinal nerve fiber layer thickness in patients with cerebral venous thrombosis.

BMC Ophthalmol 2019 Feb 20;19(1):57. Epub 2019 Feb 20.

Department of Neurology, Acıbadem Kayseri Hospital, Kayseri, Turkey.

Background: To identify thickness variations in the retinal nerve fiber layer around the optic disc and macula in patients with cerebral vein thrombosis (CVT) without papilledema.

Methods: This study included 28 patients with CVT diagnosis and appropriate treatment. Detailed ophthalmologic examination found bilateral vision 10/10, vision field test normal and fundus examination found no papilledema images. Read More

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http://dx.doi.org/10.1186/s12886-019-1046-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383271PMC
February 2019
2 Reads

The impact of age-related cataracts on colour perception, postoperative recovery and related spectra derived from test of hue perception.

BMC Ophthalmol 2019 Feb 20;19(1):56. Epub 2019 Feb 20.

Department of Ophthalmology, Peking University Third Hospital, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Number Forty-Nine North Garden Road Haidian District, Beijing, 86100191, China.

Background: Cataract patients were always excluded from studies on ageing of colour vision; thus, effect of age-related cataracts on deterioration of colour perception has not been analysed. In present study, impacts of age-related cataracts on colour discrimination, postoperative recovery and related spectra were investigated.

Methods: In this cohort study, thirty age-related cataract patients scheduled for binocular surgery and 30 elderly volunteers were enrolled. Read More

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http://dx.doi.org/10.1186/s12886-019-1057-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383292PMC
February 2019
1.075 Impact Factor

Minimal surgery achieved good visual acuity in selected patients with magnetic intravitreal foreign body and traumatic cataract.

BMC Ophthalmol 2019 Feb 19;19(1):54. Epub 2019 Feb 19.

Eye Center, Second Affiliated Hospital, School of Medicine, Zhejiang University, No. 88 Jiefang Rd, Hangzhou, 310009, China.

Background: To explore minimal surgery in selected patients with intravitreal foreign body (IVFD) and traumatic cataract.

Methods: Twelve eyes of 12 patients with small ferrous IVFD and traumatic cataract without endophthalmitis, retinal injury and secondary glaucoma, between September 2015 and March 2017 were retrospectively analyzed. Primary removal of IVFD was performed by external magnetic extraction through the pars plana incision. Read More

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https://bmcophthalmol.biomedcentral.com/articles/10.1186/s12
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http://dx.doi.org/10.1186/s12886-019-1065-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381752PMC
February 2019
10 Reads

A novel method for quantifying the biomechanical parameters of orbital soft tissue using a corneal dynamic scheimpflug analyser: a retrospective study.

BMC Ophthalmol 2019 Feb 18;19(1):53. Epub 2019 Feb 18.

Department of Ophthalmology, Seoul St. Mary's Hospital, Catholic University of Korea, Banpodaero 222, Seocho-gu, Seoul, South Korea.

Background: To demonstrate that the Corvis ST could be used to quantify the biomechanical parameters of the orbital soft tissues by measuring and comparing whole eye movement (WEM) using the Corvis in normal eyes and in eyes of patients with Graves ophthalmopathy.

Methods: Forty four eyes of 44 ophthalmologically normal subjects and 28 eyes of 28 patients with Graves ophthalmopathy were included in the study. After Corvis test, the examiners recorded WEM by air puff. Read More

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http://dx.doi.org/10.1186/s12886-019-1064-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380054PMC
February 2019
3 Reads

Structure-function relationships in glaucoma using enhanced depth imaging optical coherence tomography-derived parameters: a cross-sectional observational study.

BMC Ophthalmol 2019 02 15;19(1):52. Epub 2019 Feb 15.

Glaucoma Service, Department of Ophthalmology, Federal University of São Paulo, Rua Botucatu, 821, Vila Clementino, São Paulo, 04021-001, Brazil.

Background: To investigate structural and functional correlations in glaucoma patients using enhanced depth imaging spectral-domain optical coherence tomography (EDI OCT)-derived parameters.

Methods: We prospectively enrolled healthy participants and glaucomatous patients with a wide range of disease stages. All participants underwent visual field (VF) testing (SITA - Standard 24-2; Carl Zeiss Meditec, Dublin, CA) and EDI OCT imaging (Spectralis; Heidelberg Engineering Co. Read More

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http://dx.doi.org/10.1186/s12886-019-1054-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377769PMC
February 2019
3 Reads

Bisphosphonate-induced orbital inflammation in a patient on chronic immunosuppressive therapy.

BMC Ophthalmol 2019 Feb 14;19(1):51. Epub 2019 Feb 14.

Department of Ophthalmology, University of Kansas School of Medicine, 7400 State Line Rd, Prairie Village, Kansas, USA.

Background: To report a case of orbital inflammation after bisphosphonate infusion in a patient who was already receiving immunosuppressive therapy.

Case Presentation: A 56-year-old woman presented to the ophthalmology clinic with acute onset of right eye pain 24 h after receiving her first Zolendronic acid infusion. She has a past medical history of chronic inflammatory demyelinating polyneuropathy, Sjogren's syndrome, and systemic lupus erythematosus that have been controlled with immunosuppressive therapy for three years. Read More

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http://dx.doi.org/10.1186/s12886-019-1063-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374910PMC
February 2019
1 Read

Migraine and increased risk of developing open angle glaucoma: a population-based cohort study.

BMC Ophthalmol 2019 Feb 13;19(1):50. Epub 2019 Feb 13.

Department of Ophthalmology, National Taiwan University Hospital, Hsin-Chu Branch, Hsin-Chu, Taiwan.

Background: Migraine is linked to endothelial dysfunction and is considered to be a systemic vasculopathy. Interestingly, systemic vascular diseases also occur in glaucoma patients and are considered to be vascular risk factors. Whether migraine is simply a concomitant condition in glaucoma patients or a risk factor per se for glaucoma remains unknown. Read More

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http://dx.doi.org/10.1186/s12886-019-1062-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375150PMC
February 2019
1 Read

Comparing habitual and i. Scription refractions.

BMC Ophthalmol 2019 Feb 12;19(1):49. Epub 2019 Feb 12.

Midwestern University, College of Optometry, 19555 N 59th Ave, Glendale, Arizona, 85308, USA.

Background: Many patients voice concerns regarding poor night vision, even when they see 20/20 or better in the exam room. During mesopic and scotopic conditions the pupil size increases, increasing the effects on visual performance of uncorrected (residual) refractive errors. The i. Read More

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http://dx.doi.org/10.1186/s12886-019-1053-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373049PMC
February 2019

Carotid-cavernous fistula(CCF) presenting as paroxysmal painful ophthalmoplegia.

BMC Ophthalmol 2019 Feb 11;19(1):48. Epub 2019 Feb 11.

Department of Neurology, Shandong Provincial Hospital affiliated to Shandong University, No 324, Jingwu Road, Huaiyin Zone, Jinan, Shandong Province, 250012, People's Republic of China.

Background: Painful ophthalmoplegia can be caused by various etiologies, and broad differential diagnosis is needed. Carotid-cavernous fistula (CCF) is a rare cause of painful ophthalmoplegia, and early diagnosis is quite difficult.

Case Presentation: Here, we present a case of paroxysmal painful ophthalmoplegia caused by CCF. Read More

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http://dx.doi.org/10.1186/s12886-019-1039-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371611PMC
February 2019
2 Reads

Development of a core outcome set for amblyopia, strabismus and ocular motility disorders: a review to identify outcome measures.

BMC Ophthalmol 2019 Feb 8;19(1):47. Epub 2019 Feb 8.

Department of Health Services Research, University of Liverpool, Waterhouse Building Block B, 2nd Floor, 1-3 Brownlow Street, L69 3GL, Liverpool, UK.

Background: Core Outcome Sets (COS) are defined as the minimum sets of outcomes that should be measured and reported in all randomised controlled trials to facilitate combination and comparability of research. The aim of this review is to produce an item bank of previously reported outcome measures from published studies in amblyopia, strabismus and ocular motility disorders to initiate the development of COS.

Methods: A review was conducted to identify articles reporting outcome measures for amblyopia, strabismus and ocular motility disorders. Read More

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https://bmcophthalmol.biomedcentral.com/articles/10.1186/s12
Publisher Site
http://dx.doi.org/10.1186/s12886-019-1055-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368710PMC
February 2019
5 Reads

Ciliochoroidal detachment after Ahmed glaucoma valve implantation: a retrospective study.

BMC Ophthalmol 2019 Feb 6;19(1):46. Epub 2019 Feb 6.

Affiliated Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, Zhejiang, China.

Background: To investigate the occurrence of ciliochoroidal detachment (CCD), its risk factors and its impact on the success rate after Ahmed glaucoma valve (AGV) implantation.

Methods: This is a retrospective observational study carried out at Eye Hospital of Wenzhou Medical University, Zhejiang, China. Patients with uncontrolled glaucoma who underwent AGV implantation alone or combined with phacoemulsification (AGV-Phaco) in the hospital from April 1, 2013 to July 31, 2016 were included. Read More

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http://dx.doi.org/10.1186/s12886-019-1060-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368733PMC
February 2019
7 Reads
1.075 Impact Factor

Comparison of visual quality after EVO-ICL implantation and SMILE to select the appropriate surgical method for high myopia.

BMC Ophthalmol 2019 Feb 8;19(1):21. Epub 2019 Feb 8.

Department of Ophthalmology, Jinling Medical School of Nanjing Medical University, No. 305 East Zhongshan Road, Nanjing, 210002, Jiangsu Province, China.

Background: This study sought to compare the visual quality between intraocular collamer lens (EVO-ICL) implantation and small-incision lenticule extraction (SMILE) and determine the appropriate surgical method to treat patients with high myopia (- 6.25 to - 10 D).

Methods: A total of 48 eyes underwent EVO-ICL implantation and another 48 eyes underwent SMILE. Read More

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http://dx.doi.org/10.1186/s12886-019-1029-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367781PMC
February 2019

Retinal and choroidal thickness in paediatric patients with hypoalbuminaemia caused by nephrotic syndrome.

BMC Ophthalmol 2019 Feb 6;19(1):44. Epub 2019 Feb 6.

Department of Ophthalmology, Peking University Frist Hospital, No. 8 Xishiku Street, Xicheng District, Beijing, 100034, China.

Background: A study was conducted to evaluate the choroidal thickness (CT) and retinal thickness (RT) in paediatric patients with hypoalbuminaemia caused by nephrotic syndrome (NS). We also studied the correlation between the subfoveal choroidal thickness (SFCT) and serum protein concentration.

Methods: This was a cross-sectional study. Read More

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http://dx.doi.org/10.1186/s12886-019-1050-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364472PMC
February 2019
2 Reads

Combined phacoemulsification and viscocanalostomy with Ologen implant versus combined phacoemulsification and viscocanalostomy.

BMC Ophthalmol 2019 Feb 6;19(1):45. Epub 2019 Feb 6.

Ophthalmology Department, Zagazig University, Zagazig, 44511, Egypt.

Background: To study the efficacy of the biodegradable collagen implant Ologen® as an adjuvant in phaco-viscocanalostomy in patients with coexisting cataract and primary open angle glaucoma.

Methods: This prospective, interventional, randomized clinical study was done at Alpha Vision Center, Zagazig, Egypt. Patients with coexisting cataract and glaucoma were randomized to receive either phaco-viscocanalostomy (Phacovisco group) (39 eyes) or phaco-viscocanalostomy with Ologen® implant (OloPhacovisco group) (40 eyes). Read More

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http://dx.doi.org/10.1186/s12886-019-1049-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364460PMC
February 2019
2 Reads
1.075 Impact Factor