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    1339 results match your criteria BMC Ophthalmology[Journal]

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    A meta-analysis of the effect of a dexamethasone intravitreal implant versus intravitreal anti-vascular endothelial growth factor treatment for diabetic macular edema.
    BMC Ophthalmol 2018 May 21;18(1):121. Epub 2018 May 21.
    Department of Retina, Tianjin Medical University Eye Hospital, 251 Fukang Road, Tianjin, 300384, China.
    Background: This meta-analysis evaluated the effectiveness and safety of dexamethasone (DEX) implant and intravitreal anti-vascular endothelial growth factor (VEGF) treatment for diabetic macular edema (DME).

    Methods: The PubMed, Embase, website and Cochrane Library databases were comprehensively searched for studies comparing DEX implant with anti-VEGF in patients with DME. Read More

    Surgical peripheral iridectomy via a clear-cornea phacoemulsification incision for pupillary block following cataract surgery in acute angle closure.
    BMC Ophthalmol 2018 May 18;18(1):120. Epub 2018 May 18.
    Wenzhou Medical University Eye Hospital, Wenzhou, 325027, China.
    Background: To describe a technique of surgical peripheral iridectomy via a clear-cornea tunnel incision to prevent or treat pupillary block following phacoemulsification.

    Methods: Description of technique and retrospective description results in 20 eyes of 20 patients with acute angle closure with coexisting visually significant cataract undergoing phacoemulsification considered at risk of postoperative papillary block as well as two pseudo-phakic eyes with acute postoperative pupillary-block. Following phacoemulsification and insertion of an intraocular lens, a needle with a bent tip was inserted behind the iris through the corneal tunnel incision. Read More

    Comparison of hyperdry amniotic membrane transplantation and conjunctival autografting for primary pterygium.
    BMC Ophthalmol 2018 May 15;18(1):119. Epub 2018 May 15.
    The Second Hospital of Jilin University, No.218, Ziqiang Road, Changchun, 130041, China.
    Background: The purpose of this study was to evaluate the safety and effectiveness of the hyperdry amniotic membrane transplantation compared with conjunctival autografting for the treatment of primary pterygium.

    Methods: One hundred and forty-one eyes from 130 patients with primary pterygium were treated with excision followed by hyperdry amniotic membrane or conjunctival autografting after random selection. Seventy-nine eyes from 71 patients received hyperdry amniotic membrane transplantation (HD-AM group), and 62 eyes from 59 patients received conjunctival autografting (CG group). Read More

    Prevalence and clinical characteristics of dry eye disease in community-based type 2 diabetic patients: the Beixinjing eye study.
    BMC Ophthalmol 2018 May 10;18(1):117. Epub 2018 May 10.
    Shanghai General Hospital, Nanjing Medical University, No. 100, Haining Road, Hongkou District, Shanghai, 200080, China.
    Background: This study was performed to evaluate the prevalence and clinical characteristics of dry eye disease (DED) in community-based type 2 diabetic patients and to identify the associated factors related with DED.

    Methods: A total of 1360 type 2 diabetic patients in the Beixinjing community were randomly selected. All participants were given a questionnaire that assessed basic information and subjective symptoms. Read More

    Clinical results of the open ring PMMA guider assisted capsulorrhexis in cataract surgery.
    BMC Ophthalmol 2018 May 10;18(1):116. Epub 2018 May 10.
    Department of Ophthalmology & Visual Science, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, South Korea.
    Background: To compare the results of continuous curvilinear capsulorrhexis(CCC) after application of an open ring-shaped guider compared with a free-hand procedure in eyes with cataracts.

    Methods: This study comprised patients undergoing cataract surgery in Seoul St.Mary's Hospital, The Catholic University of Korea. Read More

    Prevalence of refractive errors in Tibetan adolescents.
    BMC Ophthalmol 2018 May 11;18(1):118. Epub 2018 May 11.
    Department of Genetics, Center for Genetics, National Research Institute for Family Planning, 12 Dahuisi Road, Haidian, Beijing, 100081, China.
    Background: The prevalence of adolescent eye disease in remote areas of the Qinghai-Tibet Plateau has rarely been reported. To understand the prevalence of common eye diseases in Tibet, we performed ocular-disease screening on students from primary and secondary schools in Tibet, and compared the prevalence to that in the Central China Plain (referred to here as the "plains area").

    Methods: The refractive status of students was evaluated with a Spot™ vision screener. Read More

    Analysis of intraocular positions of posterior implantable collamer lens by full-scale ultrasound biomicroscopy.
    BMC Ophthalmol 2018 May 9;18(1):114. Epub 2018 May 9.
    Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, People's Republic of China.
    Background: To analyze the positions of intraocular posterior Implantable Collamer Lens (ICL) and its possible relationship with vault.

    Methods: This cross-sectional study included 72 patients with high myopia (134 eyes) who were followed up after phakic intraocular lens implantation. The postoperative time ranged from 1 week to 7 years. Read More

    Clinical outcomes of Transepithelial photorefractive keratectomy to treat low to moderate myopic astigmatism.
    BMC Ophthalmol 2018 May 9;18(1):115. Epub 2018 May 9.
    Department of Ophthalmology, Peking University People's Hospital, Beijing, China.
    Background: To evaluate the refractive and visual outcomes of Transepithelial photorefractive keratectomy (TransPRK) in the treatment of low to moderate myopic astigmatism.

    Methods: This retrospective study enrolled a total of 47 eyes that had undergone Transepithelial photorefractive keratectomy. Preoperative cylinder diopters ranged from - 0. Read More

    Assessment of capillary dropout in the superficial retinal capillary plexus by optical coherence tomography angiography in the early stage of diabetic retinopathy.
    BMC Ophthalmol 2018 May 8;18(1):113. Epub 2018 May 8.
    Department of Zhengzhou Second People Hospital, Ophthalmology, Zhengzhou Eye Hospital, Zhengzhou Ophthalmic Institution, Zhengzhou Hanghai Middle Road No. 90, Zhengzhou, 450000, China.
    Background: To assess capillary dropout in the superficial retinal capillary plexus (SCP) by optical coherence tomography angiography (OCTA) in the early stage of diabetic retinopathy (DR).

    Methods: This study was a cross-sectional observational study. Patients that underwent OCTA examinations in our hospital between November 2015 and May 2016 were included in the study. Read More

    Microbial keratitis-induced endophthalmitis: incidence, symptoms, therapy, visual prognosis and outcomes.
    BMC Ophthalmol 2018 May 3;18(1):112. Epub 2018 May 3.
    Department of Ophthalmology, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22, 81675, Munich, Germany.
    Background: To evaluate symptoms, therapies and outcomes in rare microbial keratitis-induced endophthalmitis.

    Methods: Retrospective study with 11 patients treated between 2009 and 2014. Clinical findings, corneal diseases, history of steroids and trauma, use of contact lenses, number and type of surgical interventions, determination of causative organisms and visual acuity (VA) were evaluated. Read More

    The efficacy of Viscocanalostomies and combined phacoemulsification with Viscocanalostomies in the treatment of patients with glaucoma: a non-randomised observational study.
    BMC Ophthalmol 2018 May 2;18(1):111. Epub 2018 May 2.
    Stanley Eye Unit, Abergele Hospital, Llanfair Road, Abergele, Conwy, LL22 8DP, UK.
    Background: To evaluate the outcomes of Viscocanalostomy (VC) and Phacoviscocanalostomy (PV) in controlling primary and secondary glaucoma in a large cohort of patients from a single eye unit and performed by a single surgeon.

    Methods: This non-randomised, retrospective study was conducted on 620 eyes of 458 patients. All patients who had either viscocanalostomy (VC) or combined phacoemulsification and viscocanalostomy (PV) over a three-year period were included. Read More

    Manipulation of autophagy: a novelly potential therapeutic strategy for retinal neovascularization.
    BMC Ophthalmol 2018 Apr 27;18(1):110. Epub 2018 Apr 27.
    Department of Ophthalmology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, China.
    Background: The relationship between the role of VEGF and autophagy in the process of retinal angiogenesis is still unclear. In this study, we explored this issue by using the mouse retinal vascular endothelial cell (RVEC) as a model.

    Methods: RVECs were divided into the following groups: control, hypoxia (H), 3-methyladenine (3-MA) + H, VEGF + H, 3-MA + VEGF+H, anti-VEGF antibody + H, 3-MA+ anti-VEGF antibody + H. Read More

    Comparison of two techniques for toric intraocular lens implantation: hydroimplantation versus ophthalmic viscosurgical devices.
    BMC Ophthalmol 2018 Apr 24;18(1):109. Epub 2018 Apr 24.
    Department of Ophthalmology, Jinling Hospital, School of Medicine, Nanjing University, 305 East Zhongshan Road, Nanjing, People's Republic of China.
    Background: To compare the results between hydroimplantation of a single-piece, acrylic foldable toric intraocular lens (IOLs) and conventional implantation using an ophthalmic viscosurgical device (OVD).

    Methods: In this study, 60 eyes with cataract and preexisting regular corneal astigmatism of 1.0 to 3. Read More

    Combined 23-gauge transconjunctival vitrectomy and scleral fixation of intraocular lens without conjunctival dissection in managing lens complications.
    BMC Ophthalmol 2018 Apr 23;18(1):108. Epub 2018 Apr 23.
    College of Medicine, Chang Gung University, Taoyuan, Taiwan.
    Background: To evaluate the safety and efficacy of combined 23-gauge transconjunctival pars plana vitrectomy and scleral fixation of intraocular lens (IOL) without conjunctival dissection.

    Methods: A retrospective study in Chang Gung Memorial Hospital, Keelung and Taoyuan, Taiwan. Patients receiving combined 23-gauge transconjunctival pars plana vitrectomy and scleral fixation of IOL without conjunctival dissection were enrolled. Read More

    Cataract surgery in patients with corneal opacities.
    BMC Ophthalmol 2018 Apr 23;18(1):106. Epub 2018 Apr 23.
    Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou, Taiwan.
    Background: Investigating the efficacy and safety of phacoemulsification with intraocular lens (IOL) implantation in corneal opacities.

    Methods: This retrospective study was conducted in a tertiary medical center. Twenty-three eyes of 19 patients with cataracts and corneal opacities obscuring the pupillary center having received phacoemulsification with IOL insertion without any ancillary techniques were enrolled. Read More

    Characterization, treatment and prognosis of retinoblastoma with central nervous system metastasis.
    BMC Ophthalmol 2018 Apr 23;18(1):107. Epub 2018 Apr 23.
    Department of Pediatrics, Beijing Tongren Hospital, West South road 2, Yizhuang Economic and Technological Development Zone, Daxing District, Beijing, 100176, China.
    Background: Retinoblastoma is the most common primary intraocular tumor and more and more attention has been paid to the developing countries. This study was aimed to evaluate the clinical features, treatment, and prognosis of retinoblastoma patients with central nervous system (CNS) metastasis in Beijing Tongren Hospital, one of the largest tertiary eye centers in China.

    Methods: Clinical data of 31 consecutive retinoblastoma patients with CNS metastases, who were diagnosed at the Department of Pediatrics in Beijing Tongren Hospital between September 2005 and December 2015, were retrospective analyzed. Read More

    Expression of cytokines in aqueous humor from fungal keratitis patients.
    BMC Ophthalmol 2018 Apr 19;18(1):105. Epub 2018 Apr 19.
    Department of Ophthalmology and Visual Sciences, University of Louisville, 301 E. Muhammad Ali Blvd, Louisville, KY, 40202, USA.
    Background: Although a series of reports on corneal fungal infection have been published, studies on pathogenic mechanisms and inflammation-associated cytokines remain limited. In this study, aqueous humor samples from fungal keratitis patients were collected to examine cytokine patterns and cellular profile for the pathogenesis of fungal keratitis.

    Methods: The aqueous humor samples were collected from ten patients with advanced stage fungal keratitis. Read More

    Surgical factors affecting oculocardiac reflex during strabismus surgery.
    BMC Ophthalmol 2018 Apr 19;18(1):103. Epub 2018 Apr 19.
    Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea.
    Background: To investigate surgical factors associated with the occurrence of oculocardiac reflex (OCR) and changes in heart rate (HR) during strabismus surgery.

    Methods: Patients who underwent strabismus surgery under general anesthesia were enrolled in this study. The HR during surgery was measured at baseline, and at the following points during surgery: traction of the muscle, maximal increase after traction (adrenergic phase), and the cutting of the muscle. Read More

    Budget impact model of Mydrane®, a new intracameral injectable used for intra-operative mydriasis, from a UK hospital perspective.
    BMC Ophthalmol 2018 Apr 19;18(1):104. Epub 2018 Apr 19.
    Creativ-Ceutical, Paris, France.
    Background: During cataract surgery, maintaining an adequate degree of mydriasis throughout the entire operation is critical to allow for visualisation of the capsulorhexis and the crystalline lens. Good anaesthesia is also essential for safe intraocular surgery. Mydrane® is a new injectable intracameral solution containing two mydriatics (tropicamide 0. Read More

    General analysis of factors influencing cataract surgery practice in Shanghai residents.
    BMC Ophthalmol 2018 Apr 18;18(1):102. Epub 2018 Apr 18.
    Shanghai Eye Disease Prevention & Treatment Center / Shanghai Eye Hospital; Shanghai Key Laboratory of Ocular Fundus Diseases; Shanghai General Hospital; Shanghai Engineering Center for Visual Science and Photomedicine, 380 Kangding Road, Shanghai, 200040, China.
    Background: It was reported that lack of knowledge, less confidence of medical services, commute difficulties, and poor economic conditions would be the main barriers for cataract surgery practice. The influencing factors could have changed in cities with high developing speed. Shanghai is one of the biggest cities in China and the world. Read More

    The effect of fenofibrate on early retinal nerve fiber layer loss in type 2 diabetic patients: a case-control study.
    BMC Ophthalmol 2018 Apr 18;18(1):100. Epub 2018 Apr 18.
    Department of Ophthalmology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi Province, China.
    Background: Previous studies suggested that use of fenofibrate could significantly reduce the rate of progression into diabetic retinopathy (DR), and that retinal nerve fiber layer (RNFL) loss, which has been considered an important indicator for retinal neurodegeneration, might precede microvascular changes. The aim of this study was to assess the effect(s) of fenofibrate on RNFL thickness at early stage of DR in patients with type 2 diabetes mellitus (DM).

    Methods: In this retrospective matched case-control study we included a cohort of 89 patients with type 2 DM, aged 40 or above, between Jan 1, 2017 and March 31, 2017. Read More

    Central retinal artery occlusion - rethinking retinal survival time.
    BMC Ophthalmol 2018 Apr 18;18(1):101. Epub 2018 Apr 18.
    Department of Ophthalmology, University Hospitals and School of Medicine, Geneva, Switzerland.
    Background: The critical time from onset of complete occlusion of the central retinal artery (CRA) to functionally significant inner retinal infarction represents a window of opportunity for treatment and also has medical-legal implications, particularly when central retinal artery occlusion (CRAO) complicates therapeutic interventions. Here, we review the evidence for time to infarction from complete CRAO and discuss the implications of our findings.

    Methods: A Medline search was performed using each of the terms "central retinal artery occlusion", "retinal infarction", "retinal ischemia", and "cherry red spot" from 1970 to the present including articles in French and German. Read More

    Trachoma in Yunnan province of southwestern China: findings from trachoma rapid assessment.
    BMC Ophthalmol 2018 Apr 17;18(1):97. Epub 2018 Apr 17.
    Department of Ophthalmology, Yunnan Key Laboratory for prevention and treatment of eye diseases, Yunnan Innovation Team for Cataract and Ocular fundus Disease (2017HC010), Yunnan Eye Institute, Yunnan Eye Hospital, The 2nd People's Hospital of Yunnan Province, Kunming, China.
    Background: To understand the situation of active trachoma among children aged 6 to 8 years old and scarring trachoma among those aged 15 and over in Yunnan Province, South-western China.

    Methods: A rapid assessment of trachoma was conducted to determine the presence or absence of trachoma in Yunnan. Through risk assessment, 9 sites in 8 suspected trachoma epidemic counties were selected. Read More

    Ocular biometric characteristics of cataract patients in western China.
    BMC Ophthalmol 2018 Apr 17;18(1):99. Epub 2018 Apr 17.
    Department of Ophthalmology, West China Hospital of Sichuan University, Sichuan Province, Chengdu, China.
    Background: We aimed to measure ocular biometric characteristics in older cataract patients from western China.

    Methods: Ocular biometry records were retrospectively analyzed for 6933 patients with cataracts (6933 eyes) at least 50 years old who were treated at West China Hospital of Sichuan University.

    Results: Partial coherence laser interferometry gave the following population averages: axial length (AL), 24. Read More

    A cost-effectiveness study of ICT training among the visually impaired in the Netherlands.
    BMC Ophthalmol 2018 Apr 17;18(1):98. Epub 2018 Apr 17.
    Erasmus School of Health Policy & Management, Erasmus University, P.O. Box 1738, 3000, DR, Rotterdam, The Netherlands.
    Background: Due to the ageing population, the number of visually impaired people in the Netherlands will increase. To ensure the future availability of services in rehabilitative eye care, we aim to assess the cost-effectiveness of information and communication technology (ICT) training among visually impaired adults from a societal perspective, using primary data from two large rehabilitative eye care providers in the Netherlands.

    Methods: Participants were asked to fill in a questionnaire, which used six different instruments at three different time points: pre training, post training and three months post training. Read More

    TLR4 modulates inflammatory gene targets in the retina during Bacillus cereus endophthalmitis.
    BMC Ophthalmol 2018 Apr 16;18(1):96. Epub 2018 Apr 16.
    Department of Ophthalmology, University of Oklahoma Health Sciences Center, DMEI PA-419, 608 Stanton L. Young Blvd, Oklahoma City, OK, 73104, USA.
    Background: Endophthalmitis is a serious intraocular infection that frequently results in significant inflammation and vision loss. Because current therapeutics are often unsuccessful in mitigating damaging inflammation during endophthalmitis, more rational targets are needed. Toll-like receptors (TLRs) recognize specific motifs on invading pathogens and initiate the innate inflammatory response. Read More

    Characteristics of keratoconic patients at two main eye centres in Palestine: a cross-sectional study.
    BMC Ophthalmol 2018 Apr 16;18(1):95. Epub 2018 Apr 16.
    Department of Medicine, College of Medicine and Health Sciences, An-Najah National University, 44839, Nablus, Palestine, Palestine.
    Background: Keratoconus (KC) is a multifactorial, degenerative ectatic condition of the cornea. It usually manifests during late adolescence or the early twenties. A painless disease, KC may end with severe visual loss. Read More

    Identification of HO induced oxidative stress associated microRNAs in HLE-B3 cells and their clinical relevance to the progression of age-related nuclear cataract.
    BMC Ophthalmol 2018 Apr 13;18(1):93. Epub 2018 Apr 13.
    Department of Ophthalmology, Tangdu Hospital, Fourth Military Medical University, 1 Xinsi Road, Xi'an, Shaanxi, 710038, People's Republic of China.
    Background: This study is aimed to screen out the microRNAs (miRNAs) associated with HO induced oxidative stress in human lens epithelial B3 (HLE-B3) cell lines and investigate their relations with the progression of age-related nuclear cataract.

    Methods: HO was used to induce oxidative stress in HLE-B3 cells. A genome-wide expression profiling of miRNAs in HLE-B3 cells was performed to select the differentially expressed miRNAs before and after HO treatment. Read More

    A rabbit model of corneal Ectasia generated by treatment with collagenase type II.
    BMC Ophthalmol 2018 Apr 13;18(1):94. Epub 2018 Apr 13.
    Department of Ophthalmology, Peking University First Hospital, Beijing, 100034, China.
    Background: To investigate use of collagenase type II for generating a rabbit model of corneal ectasia.

    Methods: Ten New Zealand white rabbits were used with right eyes treated as the experimental group and left eyes treated as the control group. After epithelial debridement, a collagenase type II solution (200 μL of 5 mg/mL) was applied in the experimental group at room temperature (24 °C) for 30 min, and a 200 μL solution without collagenase was applied in the control group. Read More

    Acute hydrops with a 180-degree massive edematous cavern demonstrated by three dimensional view of anterior segment optical coherence tomography in a patient with pellucid marginal corneal degeneration, a case report.
    BMC Ophthalmol 2018 Apr 13;18(1):92. Epub 2018 Apr 13.
    Department of Ophthalmology, Osaka University Graduate School of Medicine, Room E7, Yamadaoka 2-2, Osaka, 565-0871, Japan.
    Background: Pellucid marginal corneal degeneration is a non-inflammatory disorder complicated by severe inferior corneal thinning. The central portion of the cornea, consequently, appears to protrude outwards, decreasing vision by means of an irregular stigmatism. Additionally, acute hydrops can occur in case of Descemet's membrane rupture. Read More

    The prevalence and systemic risk factors of diabetic macular edema: a cross-sectional study from Turkey.
    BMC Ophthalmol 2018 Apr 12;18(1):91. Epub 2018 Apr 12.
    Department of Ophthalmology, Dokuz Eylul University School of Medicine, Izmir, Turkey.
    Background: The aim of this study was to evaluate the prevalence of diabetic macular edema (DME) utilizing optical coherence tomography (OCT), and to clarify the effects of the systemic findings and risk factors on the development of DME.

    Methods: This cross-sectional study was conducted in the departments of ophthalmology and endocrinology at the Dokuz Eylul University School of Medicine in Izmir, Turkey. The demographics, type and duration of diabetes mellitus, treatment modality, smoking and alcohol consumption habits, as well as the systemic blood pressure, renal functional tests, hemoglobulin A1c level, serum lipid profile, and 24-h urine albumin level were noted and statistically analyzed. Read More

    The function and morphology of Meibomian glands in patients with thyroid eye disease: a preliminary study.
    BMC Ophthalmol 2018 Apr 12;18(1):90. Epub 2018 Apr 12.
    Department of Ophthalmology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
    Background: To investigate function and morphology of the meibomian gland (MG) in patients with thyroid eye disease (TED).

    Methods: In this prospective case series study, patients with unilateral or bilateral TED were consecutively enrolled. The diagnosis of TED was based on the typical orbital findings and/or radiographic evidence. Read More

    Multimodal imaging of foveoschisis and macular pseudohole associated with gyrate atrophy: a family report.
    BMC Ophthalmol 2018 Apr 12;18(1):89. Epub 2018 Apr 12.
    Department of Ophthalmology, Charles Nicolle University Hospital, Faculty of medicine of Tunis, University of Tunis-El Manar, 1007, Tunis, Tunisia.
    Background: To report the results of multimodal imaging of a biochemically confirmed case of a family with gyrate atrophy (GA) associated with foveoschisis and macular pseudohole.

    Case Presentation: Two sisters presented to us with progressive bilateral decreased vision. The 26-year old sister had a best corrected visual acuity (BCVA) of 20/32 in the right eye (RE) and 20/100 in the left eye (LE). Read More

    Clostridium perfringens panophthalmitis and orbital cellulitis: a case report.
    BMC Ophthalmol 2018 Apr 10;18(1):88. Epub 2018 Apr 10.
    Clinical Bacteriology Department, Amiens-Picardie University Hospital, Amiens, France.
    Background: Clostridium perfringens is an uncommon pathogen in endophthalmitis, causing rapid destruction of ocular tissues. Clostridium perfringens infection typically occurs after penetrating injury with soil-contaminated foreign bodies.

    Case Report: Here, we describe the case of a 17-year-old male who sustained a penetrating injury with a metallic intraocular foreign body and who rapidly developed severe C. Read More

    Choroidal perfusion abnormalities associated with Acute Posterior Multifocal Placoid Pigment Epitheliopathy: a case report.
    BMC Ophthalmol 2018 Apr 10;18(1):87. Epub 2018 Apr 10.
    Sacrocuore Hospital, Via Don Sempreboni 5 - Negrar, 37024, Verona, Italy.
    Background: Indocyanine Green Angiography (ICG-A) and Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography (EDI-OCT) are essential imaging techniques for diagnosis, management and understanding of the pathophysiology of many chorioretinal diseases. Herein, we report the ICG-A and EDI-OCT findings from a case of Acute Posterior Multifocal Placoid Pigment Epitheliopathy (APMPPE), in which these imaging techniques enable the visualization of more diagnostic details than those observable with other widely used diagnostic tools.

    Case Presentation: A 60-year-old white female presented with bilateral blurred vision for few days. Read More

    Species-specific characteristics of the biofilm generated in silicone tube: an in vitro study.
    BMC Ophthalmol 2018 Apr 3;18(1):85. Epub 2018 Apr 3.
    Department of Ophthalmology, Dongguk University, Ilsan Hospital, 814, Siksadong, Ilsan-dong-gu, Goyang, Gyeonggido, 410-773, South Korea.
    Background: To investigate characteristics of biofilm which is usually found in silicone tube for nasolacrimal duct surgery and can be the root of chronic bacterial infections eventually resulted in surgical failure.

    Methods: To form a biofilm, sterile silicone tube was placed in culture media of Staphylococcus aureus, Corynebacterium matruchotii, Pseudomonas aeruginosa, or Streptococcus pneumonia. Biofilms formed on these silicone tubes were fixed with 95% ethanol and stained with 0. Read More

    Theme trends and knowledge structure on choroidal neovascularization: a quantitative and co-word analysis.
    BMC Ophthalmol 2018 Apr 3;18(1):86. Epub 2018 Apr 3.
    Department of Ophthalmology, The Fourth Affiliated Hospital of China Medical University, Shenyang, China.
    Background: The distribution pattern and knowledge structure of choroidal neovascularization (CNV) was surveyed based on literatures in PubMed.

    Methods: Published scientific papers about CNV were retrieved from Jan 1st, 2012 to May 31st, 2017. Extracted MeSH terms were analyzed quantitatively by using Bibliographic Item Co-Occurrence Matrix Builder (BICOMB) and high-frequency MeSH terms were identified. Read More

    Capture of intraocular lens optic by residual capsular opening in secondary implantation: long-term follow-up.
    BMC Ophthalmol 2018 Apr 2;18(1):84. Epub 2018 Apr 2.
    Department of Ophthalmology, Xinhua Hospital, Affiliated to Medicine School of Shanghai Jiaotong University, No. 1665, Kongjiang Road, Shanghai, 200092, China.
    Background: To introduce a novel surgical technique for optic capture by residual capsular opening in secondary intraocular lens (IOL) implantation and to report the outcomes of a long follow-up.

    Methods: Twenty patients (20 eyes) who had received secondary IOL implantation with the optic capture technique were retrospectively reviewed. We used the residual capsular opening for capturing the optic and inserted the haptics in the sulcus during surgery. Read More

    Prevalence and risk factors of retinopathy of prematurity in Iran: a systematic review and meta-analysis.
    BMC Ophthalmol 2018 Apr 2;18(1):83. Epub 2018 Apr 2.
    Department of Pediatrics, Behbahan Faculty of Medical Sciences, Behbahan, Iran.
    Background: Retinopathy of prematurity (ROP) refers to the developmental disorder of the retina in premature infants and is one of the most serious and most dangerous complications in premature infants. The prevalence of ROP in Iran is different in various parts of Iran and its prevalence is reported to be 1-70% in different regions. This study aims to determine the prevalence and risk factors of ROP in Iran. Read More

    A case of silicone oil adhered to the retinal surface via perfluorocarbon liquid.
    BMC Ophthalmol 2018 Mar 27;18(1):82. Epub 2018 Mar 27.
    Department of Ophthalmology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-City, Osaka, 569-8686, Japan.
    Background: Perfluorocarbon liquid (PFCL) is widely used as an intraoperative heavy tamponade to flatten the retina and is replaced with silicone oil (SO) at the end of the surgery. Due to the long tamponade period, the SO is known to remain attached to the retina at the time of removal, and is commonly termed "sticky oil". The aim of this present study was to report a case of SO stickily attached to the retina via PFCL without tamponade period. Read More

    A quantitative analysis method for comitant exotropia using video-oculography with alternate cover.
    BMC Ophthalmol 2018 Mar 22;18(1):80. Epub 2018 Mar 22.
    Department of Ophthalmology, Yeungnam University College of Medicine, Daegu, Republic of Korea.
    Background: The purpose of this study was to evaluate the efficacy of a quantitative analysis method for comitant exotropia using video-oculography (VOG) with alternate cover.

    Methods: Thirty-four subjects with comitant exotropia were included. Two independent ophthalmologists measured the angle of ocular deviation using the alternate prism cover test (APCT). Read More

    Short-term changes of choroidal vascular structures after phacoemulsification surgery.
    BMC Ophthalmol 2018 Mar 23;18(1):81. Epub 2018 Mar 23.
    Eye Center of Shandong University, The Second Hospital of Shandong University, Shandong University, Jinan, 250000, China.
    Background: To evaluate the changes of choroidal vascular structures in patients after phacoemulsification surgery.

    Methods: A self-control study was conducted on 36 eyes of 36 patients who had uneventful phacoemulsification. Choroidal images were acquired preoperatively, 7 days (D7), 1 month (M1), and 3 months (M3) after surgery from enhanced depth imaging (EDI) optical coherence tomography (OCT) scans. Read More

    Effect of number and position of intraocular lens haptics on anterior capsule contraction: a randomized, prospective trial.
    BMC Ophthalmol 2018 Mar 20;18(1):78. Epub 2018 Mar 20.
    Department of Ophthalmology, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, Seoul, 06591, Republic of Korea.
    Background: The present study aimed to evaluate the degree of anterior capsule contraction (capsulorhexis contraction) with three different single-piece, hydrophilic acrylic intraocular lenses (IOLs).

    Methods: Patients were prospectively randomized to be implanted with one of three types of IOLs during cataract surgery: the Ophtec Precizon (IOL A), the Lucid Korea Microflex (IOL B), and the Carl Zeiss Asphina (IOL C). One week, 2 weeks, and 6 months after surgery, the area of the anterior capsule opening was measured using digital retro-illumination images after dilation of the pupil. Read More

    A white membrane beneath the inner limiting membrane of the retina in a 4-year-old child with ultrastructural evidence: a case report.
    BMC Ophthalmol 2018 Mar 20;18(1):79. Epub 2018 Mar 20.
    Department of Ophthalmology, Eye and ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China.
    Background: Epiretinal membranes (ERMs), secondary to retinal cell proliferation on the retinal surface, usually affect patients over 50 years of age but occur rarely in children. Here we report the case of a 4-year-old patient with a unilateral sub-inner limiting membrane (sub-ILM) membrane mimicking epiretinal membrane with notable ultrastructural features indicating its possible origin from old sub-ILM hemorrhage.

    Case Presentation: A 4-year-old boy was admitted with the complaint of poor vision in his right eye, which had been detected at school vision screening performed 6 months earlier. Read More

    Untreated Acute Posterior Multifocal Placoid Pigment Epitheliopathy (APMPPE): a case series.
    BMC Ophthalmol 2018 Mar 20;18(1):76. Epub 2018 Mar 20.
    Department of Ophthalmology, Hôpital Cochin, Assistance Publique Hôpitaux de Paris, Université Paris Descartes, Paris, France.
    Background: Acute Posterior Multifocal Placoid Pigment Epitheliopathy (APMPPE) is a rare inflammatory eye disease that affects the Retinal Pigment Epithelium and outer retina. The purpose of this study was to describe its presentations, as well as its prognosis in a series of untreated patients.

    Methods: Records of patients seen in the department of Ophthalmology at Cochin University Hospital, Paris, between April 2002 and June 2015 were retrospectively studied. Read More

    The Chinese Catquest-9SF: validation and application in community screenings.
    BMC Ophthalmol 2018 Mar 20;18(1):77. Epub 2018 Mar 20.
    Department of Ophthalmology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, No. 600, Yishan Road, Xuhui District, Shanghai, 200233, People's Republic of China.
    Background: The purpose of this study was to validate the Chinese Catquest-9SF questionnaire in community screenings and explore the correlation between Catquest-9SF scores and Lens Opacities Classification System (LOCS) III cataract grading.

    Methods: This was a prospective questionnaire validation study. The Catquest-9SF questionnaire was translated into Chinese and was completed by 104 Chinese cataract patients who were diagnosed in community screening. Read More

    One-year follow-up of accelerated transepithelial corneal collagen cross-linking for progressive pediatric keratoconus.
    BMC Ophthalmol 2018 Mar 9;18(1):75. Epub 2018 Mar 9.
    Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Myopia Key Laboratory of the Health Ministry, No.19 Baoqing Road, Shanghai, 200031, People's Republic of China.
    Background: Keratoconus typically presents in the teenage years and is more advanced in younger patients when compared with adults. In the present study, we aimed to assess the safety and efficacy of accelerated transepithelial corneal collagen cross-linking (ATE-CXL) in children with progressive keratoconus.

    Methods: In this retrospective consecutive study, 18 eyes were enrolled from 17 pediatric patients (15 boys and 2 girls) with a mean age of 14. Read More

    Monoclonal immunoglobulin heavy chain gene rearrangement in Fuchs' uveitis.
    BMC Ophthalmol 2018 Mar 9;18(1):74. Epub 2018 Mar 9.
    Department of Ophthalmology, University of Tokyo Graduate School of Medicine, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
    Background: Fuchs' uveitis (FU) is occasionarlly complicated with heavy vitreous opacity. We have performed vitrectomy procedures to remove vitreous opacity in affected patients as part of differential diagnosis for primary vitreoretinal lymphoma (PVRL).

    Case Presentation: We retrospectively reviewed the clinical records of five patients who first visited the Uveitis Clinic of the University of Tokyo Hospital between 2009 and 2013, were diagnosed with FU and underwent a vitrectomy for removal of dense vitreous opacity. Read More

    Prospective study of bilateral mix-and-match implantation of diffractive multifocal intraocular lenses in Koreans.
    BMC Ophthalmol 2018 Mar 7;18(1):73. Epub 2018 Mar 7.
    Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, #81 Irwon-ro, Gangnam-gu, Seoul, 06351, South Korea.
    Background: To evaluate monocular and binocular visual outcomes for near, intermediate, and far distance in patients implanted with diffractive multifocal intraocular lenses (IOLs) with different add power contralaterally.

    Methods: This is a prospective contralateral study. Two diffractive multifocal IOLs with different added power were implanted bilaterally in twenty patients. Read More

    Fundus changes in type III membranoproliferative glomerulonephritis: a case report.
    BMC Ophthalmol 2018 Mar 6;18(1):72. Epub 2018 Mar 6.
    Department of Ophthalmology, Juntendo University Faculty of Medicine, 3-1-3, Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
    Background: Membranoproliferative glomerulonephritis (MPGN) is characterized by mesangial cell proliferation and is classified into types I, II and III based on structural changes in the glomerular capillary walls. The drusen-like deposits of MPGN type II have been studied, but the fundus changes in MPGN type III have yet to be clarified. We report a case of MPGN type III with multiple deposits in the retinal pigment epithelium (RPE). Read More

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