Search our Database of Scientific Publications and Authors

I’m looking for a

    1227 results match your criteria BMC Ophthalmology[Journal]

    1 OF 25

    Transscleral tunnel incision related arterial hemorrhage in 23-gauge Vitrectomy: case report.
    BMC Ophthalmol 2018 Jan 17;18(1). Epub 2018 Jan 17.
    State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, Guangdong, 510060, China.
    Background: Transscleral tunnel incisions are commonly made to avoid postoperative leakage in small gauge sutureless vitrectomy. We present an unreported intraoperative complication, tunnel incision related arterial hemorrhage from sclerotomy, in 23-gauge (23G) vitrectomy.

    Case Presentation: Two cases of intraocular arterial hemorrhage from superonasal sclerotomy were observed at the beginning of vitrectomy. Read More

    Coping with dry eyes: a qualitative approach.
    BMC Ophthalmol 2018 Jan 16;18(1). Epub 2018 Jan 16.
    Singapore National Eye Centre, Head, Ocular Surface Research Group, Singapore Eye Research Institute, 11 Third Hospital Avenue, Singapore, 168751, Singapore.
    Background: Dry eye is a common problem that affects many people worldwide, reducing quality of life and impacting daily activities. A qualitative approach often used in medicine and other disciplines is used to evaluate how people with dry eye cope with this impact.

    Methods: Six focus group sessions were conducted at the Singapore National Eye Centre (SNEC), premises of an eye research institute. Read More

    Longitudinal observation of subretinal fibrosis in Vogt-Koyanagi-Harada disease.
    BMC Ophthalmol 2018 Jan 15;18(1). Epub 2018 Jan 15.
    Ophthalmology Department, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, 1 Shuaifuyuan, Wangfujing, Dongcheng District, Beijing, 100730, China.
    Background: Subretinal fibrosis (SRF) is a vision-threatening complication of Vogt-Koyanagi-Harada disease (VKH). It has long been recognized as a sequela of chronic inflammation. The developmental process of SRF, however, has not been described. Read More

    Relationship between corneal biomechanical properties and structural biomarkers in patients with normal-tension glaucoma: a retrospective study.
    BMC Ophthalmol 2018 Jan 15;18(1). Epub 2018 Jan 15.
    Department of Ophthalmology, Pusan National University School of Medicine, #179 Gudeok-ro, Seo-gu, Busan, 602-739, South Korea.
    Background: We evaluated the relationships between corneal biomechanical properties and structural parameters in patients with newly diagnosed, untreated normal-tension glaucoma (NTG).

    Methods: All subjects were evaluated using an Ocular Response Analyzer (ORA) measuring corneal hysteresis (CH) and the corneal resistance factor (CRF). Central corneal thickness (CCT), Goldmann applanation tonometric (GAT) data, axial length, and the spherical equivalent (SE), were also measured. Read More

    Exophthalmos in a young woman with no graves' disease - a case report of IgG4-related orbitopathy.
    BMC Ophthalmol 2018 Jan 12;18(1). Epub 2018 Jan 12.
    Division of Endocrinology, Department of Medicine, Faculty of Medicine, University of Debrecen, Nagyerdei krt 98, Debrecen, 4032, Hungary.
    Background: Immunoglobulin G4-related disease (IgG4-rd) is characterized by lymphoplasmacytic infiltration and tissue fibrosis. Orbital manifestations of IgG4-rd may include unilateral or bilateral proptosis, cicatricial extraocular muscle myopathy, orbital inflammation and pain which may mimic ophthalmic Graves' disease.

    Case Presentation: A 25-year-old woman has been referred to the endocrinology clinic, 4 months after delivery, with suspected Graves' orbitopathy. Read More

    Monocular lens dislocation due to vomiting-a case report.
    BMC Ophthalmol 2018 Jan 8;18(1). Epub 2018 Jan 8.
    Department of Ophthalmology, the First People'S Hospital of Xian yang, #10 Biyuan Road, Xian yang, Shaanxi, 712000, China.
    Background: Lens dislocation is a common disease in ophthalmology, which leads to vision loss, while the lens dislocation caused by vomiting has not been reported yet. We report a case of lens dislocation caused by simple vomiting. This case further implicated for the pathogenesis of lens dislocation. Read More

    Impending extrusion of Ex-PRESS shunt treated by shunt-position adjustment: a case report.
    BMC Ophthalmol 2018 Jan 8;18(1). Epub 2018 Jan 8.
    Happy Eye21 Hospital, 950, Mujin-daero, Seo-gu, Gwangju, 61932, Republic of Korea.
    Background: To report a case of impending extrusion of Ex-PRESS shunt treated by shunt-position adjustment.

    Case Presentation: A 56-year-old Asian woman presented with impending extrusion and malposition of Ex-PRESS shunt in her left eye. The bleb of the left eye was shallow and diffuse. Read More

    Goldmann and error correcting tonometry prisms compared to intracameral pressure.
    BMC Ophthalmol 2018 Jan 4;18(1). Epub 2018 Jan 4.
    Department of Ophthalmology, University of Arizona-College of Optical Science, University of Arizona-College of Medicine, 1630 E. University Blvd, Tucson, AZ, 85719, USA.
    Background: Compare Goldmann applanation tonometer (GAT) prism and correcting applanation tonometry surface (CATS) prism to intracameral intraocular pressure (IOP), in vivo and in vitro.

    Methods: Pressure transducer intracameral IOP was measured on fifty-eight (58) eyes undergoing cataract surgery and the IOP was modulated manometrically to 10, 20, and 40 mmHg. Simultaneously, IOP was measured using a Perkins tonometer with a standard GAT prism and a CATS prism at each of the intracameral pressures. Read More

    Epithelial changes with corneal punctate epitheliopathy in type 2 diabetes mellitus and their correlation with time to healing.
    BMC Ophthalmol 2018 Jan 4;18(1). Epub 2018 Jan 4.
    Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University; Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing, 100730, China.
    Background: To study basal epithelial cell (BEC), sub-basal nerve plexus (SBN) and Langerhans cell (LC) density in patients with type 2 diabetes mellitus (T2DM) with corneal punctate epitheliopathy (CPE) and to assess their association with time to healing of CPE.

    Methods: Retrospective study of in vivo confocal microscopy (IVCM) in 160 eyes from 160 patients with T2DM diagnosed with CPE due to a single cause. Key exclusion criteria included multiple-causes for CPE or treatment with autologous serum. Read More

    Segmentation error in spectral domain optical coherence tomography measures of the retinal nerve fibre layer thickness in idiopathic intracranial hypertension.
    BMC Ophthalmol 2018 Jan 4;17(1):257. Epub 2018 Jan 4.
    Institute of Metabolism and Systems Research, University of Birmingham, B15 2TT, Birmingham, UK.
    Background: Optical Coherence Tomography (OCT) imaging is being increasingly used in clinical practice for the monitoring of papilloedema. The aim is to characterise the extent and location of the Retinal Nerve Fibre Layer (RNFL) Thickness automated segmentation error (SegE) by manual refinement, in a cohort of Idiopathic Intracranial Hypertension (IIH) patients with papilloedema and compare this to controls.

    Methods: Baseline Spectral Domain OCT (SDOCT) scans from patients with IIH, and controls with no retinal or optic nerve pathology, were examined. Read More

    Visual rehabilitation in moderate keratoconus: combined corneal wavefront-guided transepithelial photorefractive keratectomy and high-fluence accelerated corneal collagen cross-linking after intracorneal ring segment implantation.
    BMC Ophthalmol 2017 Dec 29;17(1):270. Epub 2017 Dec 29.
    The Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, 50 Yonseiro, Seodaemungu, Seoul, 03722, South Korea.
    Background: To investigate the effects of combined corneal wavefront-guided transepithelial photorefractive keratectomy (tPRK) and accelerated corneal collagen cross-linking (CXL) after intracorneal ring segment (ICRS) implantation in patients with moderate keratoconus.

    Methods: Medical records of 23 eyes of 23 patients undergoing combined tPRK and CXL after ICRS implantation were retrospectively analyzed. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), manifest refraction spherical equivalent (MRSE), corneal indices based on Scheimpflug tomography, higher-order aberrations (HOAs), and corneal biomechanical properties were evaluated before and after ICRS implantation, and at 1, 3, and 6 months after combined tPRK and CXL. Read More

    Experimental research on the relationship between the stiffness and the expressions of fibronectin proteins and adaptor proteins of rat trabecular meshwork cells.
    BMC Ophthalmol 2017 Dec 29;17(1):268. Epub 2017 Dec 29.
    Department of Biomechanics and Rehabilitation Engineering, School of Biomedical Engineering, Capital Medical University, No.10 Xitoutiao, You An Men, Beijing, 100069, People's Republic of China.
    Background: Trabecular meshwork (TM) plays an important role in maintaining normal intraocular pressure (IOP). Studies have shown that glaucomatous TM tissues are stiffer than those of normal tissue. The high expression of fibronectin protein (FN) and adaptor protein (LNK) may be related to high resistance to aqueous humor outflow as well as high IOP. Read More

    Mapping standard ophthalmic outcome sets to metrics currently reported in eight eye hospitals.
    BMC Ophthalmol 2017 Dec 29;17(1):269. Epub 2017 Dec 29.
    Moorfields Eye Hospital NHS Foundation Trust, London, UK.
    Background: To determine alignment of proposed international standard outcomes sets for ophthalmic conditions to metrics currently reported by eye hospitals.

    Methods: Mixed methods comparative benchmark study, including eight eye hospitals in Australia, India, Singapore, Sweden, U.K. Read More

    Comparison of efficacy between coaxial microincision and standard-incision phacoemulsification in patients with age-related cataracts: a meta-analysis.
    BMC Ophthalmol 2017 Dec 29;17(1):267. Epub 2017 Dec 29.
    School of Public Health, Xi'an Jiaotong University Health Science Center, 76 West Yanta Road, Xi'an, 710061, China.
    Background: Incision size plays a critical role in the efficacy of cataract surgery, but the available evidence on ideal incision size is inconsistent. In this study, we conducted a meta-analysis to evaluate the efficacy of coaxial microincisional phacoemulsification surgery (MICS) compared with that of standard-incision phacoemulsification surgery (SICS) in patients with age-related cataracts.

    Methods: The Cochrane Library (Wiley Online Library), PubMed, Medline, National Knowledge Infrastructure (CNKI), and VIP databases were searched to identify reports of clinical randomized controlled trials (RCTs) comparing MICS to SICS for the treatment of age-related cataracts. Read More

    Unilateral lateral rectus muscle advancement surgery based on one-fourth of the angle of consecutive esotropia.
    BMC Ophthalmol 2017 Dec 29;17(1):266. Epub 2017 Dec 29.
    Department of Ophthalmology, Haeundae Paik Hospital, Inje University College of Medicine, 875 Haeundae-Ro, Haeundae-Gu, Busan, 612-896, South Korea.
    Background: To evaluate the efficacy of unilateral lateral rectus muscle advancement surgery based on one-fourth of the angle of consecutive esotropia within 25 prism diopters (PD) occurring after bilateral lateral rectus muscle recession for intermittent exotropia.

    Methods: Medical records of 11 patients who underwent unilateral lateral rectus muscle advancement for consecutive esotropia from 2011 to 2014 and who were observed for at least 6 months after surgery were retrospectively reviewed. The change in angle of deviation from before to after consecutive esotropia surgery, as well as the success rate and surgical effect, were evaluated. Read More

    Study design and baseline findings from the progression of ocular findings (PROOF) natural history study of dry eye.
    BMC Ophthalmol 2017 Dec 28;17(1):265. Epub 2017 Dec 28.
    , Allergan plc, 2525 Dupont Drive, Irvine, CA, 92612, USA.
    Background: The aim of this research is to initiate a 5-year natural history study of dry eye disease (DED) using objectively assessed and patient-reported outcomes, to explore the hypothesis that DED is a progressive condition that has substantive and measurable impacts not only on the ocular surface, but on quality of life and visual functioning. Our objective for this report is to examine the baseline data.

    Methods: A multicenter, prospective, controlled, observational study of Level 2 (mild-to-moderate) DED patients based on International Task Force Delphi Panel severity grading, and controls, documented baseline measures (including tear film biomarkers and quality of life). Read More

    Ratios for double silicone oil Endotamponade - in vitro observations may assist with ratio selection.
    BMC Ophthalmol 2017 Dec 28;17(1):264. Epub 2017 Dec 28.
    Ophthalmology Department, St Mary's Hospital, Parkhurst Road, Newport, Isle of Wight, PO30 5TG, UK.
    Background: Silicone oil tamponade is more frequently reserved for cases of complex retinal detachment. We describe the effects of different variations in oil ratios with the relatively unknown technique of double oil tamponade.

    Methods: Retrospective case note review of nine patients with complex rhegmatogenous retinal detachment (RD). Read More

    Efficacy and safety of transepithelial corneal collagen crosslinking surgery versus standard corneal collagen crosslinking surgery for keratoconus: a meta-analysis of randomized controlled trials.
    BMC Ophthalmol 2017 Dec 28;17(1):262. Epub 2017 Dec 28.
    Department of Ophthalmology, Tongde Hospital of Zhejiang Province, 234 Gucui Road, Hangzhou, 310012, China.
    Background: The aim of this study was to evaluate the efficacy and safety of transepithelial corneal collagen crosslinking (transepithelial CXL) versus standard corneal collagen crosslinking (epithelium-off CXL) on keratoconus.

    Methods: Eligible studies were identified by systematically searching PubMed, the Cochrane Library and Embase. Topographic parameters, corrected distant visual acuity (CDVA), uncorrected distant visual acuity (UDVA), and corneal thickness (CT) were assessed by the pooled weighted mean differences (WMDs) of the change from baseline to the end of follow up. Read More

    Assessment of visual morbidity amongst diabetic retinopathy at tertiary eye care center, Nepal: a cross-sectional descriptive study.
    BMC Ophthalmol 2017 Dec 28;17(1):263. Epub 2017 Dec 28.
    Universal College of Medical Sciences, Bhairahawa, Nepal.
    Background: Diabetic retinopathy (DR) is one of the leading causes of preventable blindness in low and middle income countries. In Nepal, there are less studies regarding DR and they too are limited around Kathmandu valley. This study was done to assess visual morbidity in patients with DR at a peripheral tertiary eye care center of Nepal. Read More

    Influence of corneal power on intraocular lens power of the second eye in the SRK/T formula in bilateral cataract surgery.
    BMC Ophthalmol 2017 Dec 28;17(1):261. Epub 2017 Dec 28.
    Department of Ophthalmology, Korea University College of Medicine, Seoul, South Korea.
    Background: To evaluate the effect of different adjustments of the refractive outcome of the first eye according to corneal power (K) in order to improve the intraocular lens (IOL) power calculation of the second eye in the SRK/T formula.

    Methods: One hundred thirty-four patients who underwent uncomplicated bilateral, sequential phacoemulsification with AcrySof IQ implantation were enrolled. The optimal partial adjustment of the refractive outcome of the first eye according to K was retrospectively analyzed using a regression formula. Read More

    Outcomes of and barriers to cataract surgery in Sao Paulo State, Brazil.
    BMC Ophthalmol 2017 Dec 22;17(1):259. Epub 2017 Dec 22.
    Universidade Estadual Paulista Julio de Mesquita Filho Faculdade de Medicina Campus de Botucatu Botucatu, Sao Paulo, Brazil.
    Background: Cataract is the leading cause of blindness in developing countries and identification of the barriers to accessing treatment is essential for developing appropriate public healthcare interventions. To evaluate the barriers to cataract surgery after diagnosis and assess the postoperative outcomes in Sao Paolo State, Brazil.

    Methods: This prospective study evaluated cataract patients from 13 counties in São Paulo State in 2014. Read More

    Buffering zone of implantable Collamer lens sizing in V4c.
    BMC Ophthalmol 2017 Dec 22;17(1):260. Epub 2017 Dec 22.
    Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, #81 Irwon-ro, Gangnam-gu, Seoul, 06351, South Korea.
    Background: The purpose of this study was to identify factors related to the unexpected vault in V4c implantable collamer lens (ICL; STAAR Surgical) implantation.

    Methods: V4c ICLs were implanted in 43 eyes of 43 patients for the correction of myopia. The implanted V4c ICL sizes were determined individually with our previous V4 ICL sizing nomogram based on the sulcus-to-sulcus diameter (STS), and the V4 ICL sizes were then converted to V4c ICL sizes with a size-converting table. Read More

    Visual symptoms associated with refractive errors among Thangka artists of Kathmandu valley.
    BMC Ophthalmol 2017 Dec 21;17(1):258. Epub 2017 Dec 21.
    BP Koirala Lions Center for Ophthalmic Studies, Maharajgunj Medical Campus, Institute of Medicine, Tribhuvan University, Maharajgunj, Kathmandu, Nepal.
    Background: Prolong near work, especially among people with uncorrected refractive error is considered a potential source of visual symptoms. The present study aims to determine the visual symptoms and the association of those with refractive errors among Thangka artists.

    Methods: In a descriptive cross-sectional study, 242 (46. Read More

    Incidental branch retinal artery occlusion on optical coherence tomography angiography presenting as segmental optic atrophy in a child: a case report.
    BMC Ophthalmol 2017 Dec 19;17(1):256. Epub 2017 Dec 19.
    Department of Ophthalmology, Maryknoll Medical Center, 121, Junggu-ro, Jung-gu, Busan, 48972, South Korea.
    Background: Retinal artery occlusion is extremely rare in the pediatric population and most patients have risk factors. We report a case of a healthy child with segmental optic atrophy, complicated by incidental branch retinal artery occlusion (BRAO).

    Case Presentation: A 10-year-old boy who had a history of his mother's gestational diabetes presented with an inferonasal visual field defect in the left eye. Read More

    Proteomics analysis and proteogenomic characterization of different physiopathological human lenses.
    BMC Ophthalmol 2017 Dec 19;17(1):253. Epub 2017 Dec 19.
    State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 54# Xianlie Road, Guangzhou, Guangdong, 510060, China.
    Background: The aim of the present study was to identify the proteomic differences among human lenses in different physiopathological states and to screen for susceptibility genes/proteins via proteogenomic characterization.

    Methods: The total proteomes identified across the regenerative lens with secondary cataract (RLSC), congenital cataract (CC) and age-related cataract (ARC) groups were compared to those of normal lenses using isobaric tagging for relative and absolute protein quantification (iTRAQ). The up-regulated proteins between the groups were subjected to biological analysis. Read More

    A case of proliferative diabetic retinopathy in which scintillating particles appeared in the intravitreal cavity after laser photocoagulation.
    BMC Ophthalmol 2017 Dec 19;17(1):254. Epub 2017 Dec 19.
    Department of Ophthalmology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki City, Osaka, 569-8686, Japan.
    Background: To report a case of proliferative diabetic retinopathy (PDR) exhibiting the appearance of scintillating particles presumed to be crystallin inside the intravitreal cavity after laser photocoagulation.

    Case Presentation: A 56-year-old male patient presented at our outpatient clinic after becoming aware of decreased vision in his right eye. Ocular examination performed at the patient's initial visit revealed a massive preretinal macular hemorrhage due to PDR in his right eye. Read More

    Atypical acute retinal necrosis accompanied by Terson's syndrome: a case report.
    BMC Ophthalmol 2017 Dec 19;17(1):255. Epub 2017 Dec 19.
    Department of Ophthalmology, Jeju National University Hospital, Jeju National University School of Medicine, 1753-3 Ara-1 Dong, Jeju-Si, Jeju Self-Governing Province, Republic of Korea.
    Background: Acute retinal necrosis (ARN) has characterized by panuveitis, vitritis, severe vaso-occlusive vasculitis, and diffuse necrotizing retinitis. There are no case reports on atypical ARN combined with Terson's syndrome. Herein, we report a case of ARN with atypical clinical features combined with Terson's syndrome that we successfully treated by intravitreal ganciclovir injection. Read More

    The application of wide-field laser ophthalmoscopy in fundus examination before myopic refractive surgery.
    BMC Ophthalmol 2017 Dec 15;17(1):250. Epub 2017 Dec 15.
    Department of Ophthalmology, Shanghai Tenth People's Hospital, Tong Ji University, Shanghai, 200072, China.
    Background: To evaluate wide-field laser ophthalmoscopy (Optomap 200Tx) for screening retinal lesions before myopic refractive surgery.

    Methods: Seventy-eight eyes of 78 consecutive refractive surgery candidates were included in this study. All subjects underwent Optomap 200Tx, mydriatic slit-lamp lens examination and the Goldmann three-mirror contact lens examination, which was considered as the reference method for determining retinal lesions. Read More

    Dexamethasone implants in paediatric patients with noninfectious intermediate or posterior uveitis: first prospective exploratory case series.
    BMC Ophthalmol 2017 Dec 16;17(1):252. Epub 2017 Dec 16.
    Department of Ophthalmology, Campus Virchow- Klinikum, Charité - University Medicine Berlin, corporate member of Freie Universität Berlin, Humboldt- Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.
    Background: To evaluate the efficacy and safety of dexamethasone (DEX) implants in paediatric patients with noninfectious intermediate or posterior uveitis.

    Methods: Prospective single center exploratory case series. Children and adolescents, 6 to 17 years old, with a vitreous haze score of ≥1. Read More

    Structural changes of the macula and optic nerve head in the remaining eyes after enucleation for retinoblastoma: an optical coherence tomography study.
    BMC Ophthalmol 2017 Dec 16;17(1):251. Epub 2017 Dec 16.
    Ophthalmology Department, Faculty of Medicine, Ain Shams University, Corresponding author address: 10 th Fawzy Elmoteay street, Heliopolis, Cairo, Postal code: 11736, Egypt.
    Background: To describe objectively the possible structural changes of the macula and optic nerve head in the free eyes of unilateral cured retinoblastoma patients and, also after enucleation using spectral domain optical coherence tomography.

    Methods: A cross sectional study involving 60 patients subdivided into three groups; 15 unilateral RB patients in whom enucleation was indicated as a sole treatment performed earlier in life [(study group (I)], 15 unilateral RB patients who had completely regressed disease with a preserved eye [(study group (II)] and 30 age and sex matched healthy controls. The remaining and free eyes in study groups and right eyes of control group had full ophthalmological examination, static automated perimetry and optical coherence tomography of the macula and optic nerve head. Read More

    Vitreous hemorrhage and Rhegmatogenous retinal detachment that developed after botulinum toxin injection to the extraocular muscle: case report.
    BMC Ophthalmol 2017 Dec 13;17(1):249. Epub 2017 Dec 13.
    Department of Ophthalmology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea.
    Background: The authors report a case of a rare complication that occurred after botulinum toxin injection to the extraocular muscle, which was easily overlooked and successfully corrected by surgery.

    Case Presentation: A 34-year-old female patient visited our clinic for diplopia and ocular motility disorder after removal of an epidermoid tumor of the brain. At her initial visit, her best-corrected visual acuity (BCVA) was 20/20 for both eyes. Read More

    The impact of glaucoma on quality of life in Ethiopia: a case-control study.
    BMC Ophthalmol 2017 Dec 13;17(1):248. Epub 2017 Dec 13.
    International Centre for Eye Health, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK.
    Background: Glaucoma is a chronic disease characterized by irreversible optic nerve damage and visual field loss that leads to visual impairment and blindness; ultimately limiting personal independence and compromising overall quality of life of affected individuals. There is paucity of information on how glaucoma affects the quality of life of patients in low and middle-income countries where resources for both diagnosis and treatment of such conditions are limited. In this study we investigate the impact of glaucoma on quality of life in Ethiopian patients. Read More

    Increase in esodeviation under cycloplegia with 0.5% tropicamide and 0.5% phenylephrine mixed eye drops in patients with hyperopia and esotropia.
    BMC Ophthalmol 2017 Dec 12;17(1):247. Epub 2017 Dec 12.
    Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
    Backgroud: To evaluate the manifestations of increased esodeviation under cycloplegia with 0.5% tropicamide and 0.5% phenylephrine in children with hyperopia and esotropia. Read More

    Qualitative and quantitative evaluation of acute angle-closure mechanisms.
    BMC Ophthalmol 2017 Dec 11;17(1):246. Epub 2017 Dec 11.
    From the Department of Ophthalmology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
    Background: To evaluate ocular biometric parameters in different subtypes of acute angle closure and compared to fellow eyes of AAC and PACS eyes.

    Methods: This is a retrospective chart review study. A total of 167 eyes (96 patients) consisting of 71 AAC eyes, 71 fellow eyes of AAC, and 25 PACS eyes were recruited. Read More

    Late-onset diffuse lamellar keratitis 4 years after femtosecond laser-assisted small incision lenticule extraction: a case report.
    BMC Ophthalmol 2017 Dec 8;17(1):244. Epub 2017 Dec 8.
    School of Medicine, New York University, New York, USA.
    Background: To report a first case of late-onset diffuse lamellar keratitis (DLK) occurring 4 years after femtosecond laser-assisted small incision lenticule extraction (SMILE).

    Case Presentation: A 41-year-old man who underwent SMILE 4 years prior developed DLK in the right eye 1 day after he was struck in the eye by a finger while playing with his son. Slim-lamp microscopy and anterior segment optical coherence tomography (AS-OCT) were used to evaluate the cornea of the right eye. Read More

    Effect of Orthokeratology on myopia progression: twelve-year results of a retrospective cohort study.
    BMC Ophthalmol 2017 Dec 8;17(1):243. Epub 2017 Dec 8.
    Department of Ophthalmology, Buddhist Tzu Chi General Hospital, No. 707, Sec. 3, Zhongyang Rd, Hualien City, 97002, Taiwan.
    Background: Several studies reported the efficacy of orthokeratology for myopia control. Somehow, there is limited publication with follow-up longer than 3 years. This study aims to research whether overnight orthokeratology influences the progression rate of the manifest refractive error of myopic children in a longer follow-up period (up to 12 years). Read More

    Acute clouding of trifocal lens during implantation: a case report.
    BMC Ophthalmol 2017 Dec 8;17(1):242. Epub 2017 Dec 8.
    Shanxi Eye Hospital, No. 100 Fudong Street, Taiyuan, Shanxi, 030002, People's Republic of China.
    Background: Intraoperative IOLs clouding of several kinds of hydrophilic acrylic intraocular lenses (IOLs) have been reported due to temperature changes. This phenomenon reported previously occurred in cold countries and during the winter months. However, no clinical case was reported about trifocal IOL opacification during operation. Read More

    What does IGRA testing add to the diagnosis of ocular tuberculosis? A Bayesian latent class analysis.
    BMC Ophthalmol 2017 Dec 8;17(1):245. Epub 2017 Dec 8.
    Moorfields Eye Hospital, NHS Foundation Trust, London, UK.
    Background: To evaluate the contribution made to the diagnostic work-up for patients with suspected ocular tuberculosis (TB) by QuantiFERON-TB Gold In-Tube (QFT) tests using latent class analysis model.

    Methods: A single centre retrospective cohort study. A Bayesian latent class model was constructed on the basis of demographics, phenotypes and test results from patients attending a tertiary referral center in the UK. Read More

    A pilot investigation of audiovisual processing and multisensory integration in patients with inherited retinal dystrophies.
    BMC Ophthalmol 2017 Dec 7;17(1):240. Epub 2017 Dec 7.
    Department of Anatomy and Neurobiology, University of Tennessee Health Sciences Center, Memphis, TN, 38163, USA.
    Background: In this study, we examined audiovisual (AV) processing in normal and visually impaired individuals who exhibit partial loss of vision due to inherited retinal dystrophies (IRDs).

    Methods: Two groups were analyzed for this pilot study: Group 1 was composed of IRD participants: two with autosomal dominant retinitis pigmentosa (RP), two with autosomal recessive cone-rod dystrophy (CORD), and two with the related complex disorder, Bardet-Biedl syndrome (BBS); Group 2 was composed of 15 non-IRD participants (controls). Audiovisual looming and receding stimuli (conveying perceptual motion) were used to assess the cortical processing and integration of unimodal (A or V) and multimodal (AV) sensory cues. Read More

    Association of ARMS2 genotype with response to anti-vascular endothelial growth factor treatment in polypoidal choroidal vasculopathy.
    BMC Ophthalmol 2017 Dec 7;17(1):241. Epub 2017 Dec 7.
    Department of Ophthalmology, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul, 110-799, South Korea.
    Background: To investigate whether genetic risk variants for age-related macular degeneration (AMD) are associated with response to intravitreal anti-vascular endothelial growth factor (VEGF) in polypoidal choroidal vasculopathy (PCV) patients.

    Methods: This prospective cohort study included 95 treatment-naïve patients that underwent anti-VEGF treatment for PCV for 12 months. Patients were genotyped for 10 single nucleotide polymorphisms in eight AMD-relevant genes. Read More

    Clinical features of visual disturbances secondary to isolated sphenoid sinus inflammatory diseases.
    BMC Ophthalmol 2017 Dec 6;17(1):237. Epub 2017 Dec 6.
    Department of Ophthalmology, University of Colorado School of Medicine, Aurora, CO, USA.
    Background: Visual disturbances associated with isolated sphenoid sinus inflammatory diseases (ISSIDs) are easily misdiagnosed due to the nonspecific symptoms and undetectable anatomical location. The main objective of this retrospective case series is to investigate the clinical features of visual disturbances secondary to ISSIDs.

    Methods: Clinical data of 23 patients with unilateral or bilateral visual disturbances secondary to ISSIDs from 2004 to 2014 with new symptoms were collected. Read More

    Early anti-VEGF treatment for hemorrhagic occlusive retinal vasculitis as a complication of cataract surgery.
    BMC Ophthalmol 2017 Dec 6;17(1):238. Epub 2017 Dec 6.
    First Division of Ophthalmology, School of Medicine, National and Kapodistrian University of Athens, "G. Gennimatas" General Hospital of Athens, Athens, Greece.
    Background: We report a case of hemorrhagic occlusive retinal vasculitis (HORV) after prophylactic intracameral vancomycin use during an uneventful cataract surgery treated with early anti-VEGF treatment.

    Case Presentation: A 51-year-old female underwent uneventful cataract surgery with prophylactic intracameral vancomycin during the procedure. On the seventh post-operative-day, she presented with sudden painful, visual loss. Read More

    Case report: bilateral Mooren ulcer in association with hepatitis C.
    BMC Ophthalmol 2017 Dec 6;17(1):239. Epub 2017 Dec 6.
    Department of Ophthalmology, Turku University Hospital, PO Box 52, FIN-20521, Turku, Finland.
    Background: Mooren ulcer has been considered as an idiopathic autoimmune keratitis. However, it has been in some cases suggested to be associated with hepatitis C, although the evidence is very vague.

    Case Presentation: We present a case of a man who was diagnosed with a primary Mooren ulcer in his right eye. Read More

    Long-term follow-up after scleral lens fixation in patients with Marfan syndrome.
    BMC Ophthalmol 2017 Dec 6;17(1):235. Epub 2017 Dec 6.
    Eye Center, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
    Background: The dislocation of the crystalline lens is a common finding in patients with Marfan syndrome (MFS). Scleral intraocular lens (IOL) fixation is an accepted treatment method of this complication. To now, no long-term data on scleral IOL fixation in MFS exist. Read More

    Acute Zonal Occult Outer Retinopathy (AZOOR): a case report of vision improvement after intravitreal injection of Ozurdex.
    BMC Ophthalmol 2017 Dec 6;17(1):236. Epub 2017 Dec 6.
    Institute of Eye Research, Buddhist Tzu Chi General Hospital, Tzu Chi University, 707, Sec. 3, Chung-Yang Rd., Hualien, 970, Taiwan.
    Background: AZOOR was first described by Gass in 1993 as a syndrome with rapid loss of one or more extensive zones of the outer retinal segments. It is characterized by photopsia, minimal funduscopic changes, and electroretinographic abnormalities. The efficacy of systemic steroids in treating AZOOR has been previously described and advocated by the concept of autoimmune retinopathy. Read More

    Injections frequency and health care costs in patients treated with aflibercept compared to ranibizumab: new real-life evidence from Switzerland.
    BMC Ophthalmol 2017 Dec 4;17(1):234. Epub 2017 Dec 4.
    Department of Health Sciences, Helsana Group, P.O. Box, Zürich, Switzerland.
    Background: Previous analyses of real-life data indicated that injection frequency and health care costs did not differ for anti-VEGF treatment with aflibercept and ranibizumab. The objective of this study was to investigate whether this finding persisted when analysing a longer time period after licensing.

    Methods: Retrospective analysis of health insurance claims data of two large Swiss basic health insurance plans including 28% of the Swiss population. Read More

    Complete occlusion of anterior capsulorhexis after uneventful cataract surgery, treated with YAG laser capsulotomy.
    BMC Ophthalmol 2017 Dec 4;17(1):233. Epub 2017 Dec 4.
    Myung-Gok Eye Research Institute, Department of Ophthalmology, Kim's Eye Hospital, Konyang University College of Medicine, 136, Yeongsin-ro, Yeongdeungpo-gu, Seoul, 07301, Korea.
    Background: Capsular contraction syndrome (CCS) has been reported as an uncommon complication after an cataract extraction surgery with intact anterior capsulorhexis. This report is written to present a case of complete occlusion of the anterior capsulorhexis opening after an uneventful cataract surgery, which was treated with non-invasive treatment.

    Case Presentation: A 69-year-old woman complained of decreased visual acuity in her right eye, which had started 2 months ago. Read More

    Portable acuity screening for any school: validation of patched HOTV with amblyopic patients and Bangerter normals.
    BMC Ophthalmol 2017 Dec 4;17(1):232. Epub 2017 Dec 4.
    Alaska Blind Child Discovery, Alaska Children's EYE & Strabismus, 3500 Latouche #280, Anchorage, Alaska, 99508, USA.
    Background: We needed to validate and calibrate our portable acuity screening tools so amblyopia could be detected quickly and effectively at school entry.

    Methods: Spiral-bound flip cards and download pdf surround HOTV acuity test box with critical lines were combined with a matching card. Amblyopic patients performed critical line, then threshold acuity which was then compared to patched E-ETDRS acuity. Read More

    Ten years follow-up after surgery for a foveal detachment due to optic disc pit: a case report of outer retinal layer healing.
    BMC Ophthalmol 2017 Dec 4;17(1):231. Epub 2017 Dec 4.
    Monticelli-Paradis Center, 13008, Marseille, France.
    Background: To report a case of complete progressive visual recovery and healing of outer retinal layers after vitrectomy for foveal detachment associated with optic disc pit.

    Case Presentation: Optical coherence tomography (OCT) follow-up was performed on a 15-year-old boy with deep optic disc pit and foveal detachment, before and for 10 years after vitrectomy with gas. The foveal detachment was successfully reattached with complete reapplication of the retina. Read More

    Prevalence and associated factors of strabismus in former preterm and full-term infants between 4 and 10 Years of age.
    BMC Ophthalmol 2017 Dec 2;17(1):228. Epub 2017 Dec 2.
    Department of Paediatrics, Helios Dr. Horst Schmidt Klinik, Wiesbaden, Germany.
    Background: Limited data exist collating most of the associated factors for strabismus in one analysis. The aim of this study was to assess the prevalence of strabismus and to analyse associated factors in former preterm and full-term infants.

    Methods: In this cross-sectional study, 239 former preterm infants with gestational age (GA) ≤ 32 weeks and 264 former full-term born infants with GA ≥ 37 weeks underwent detailed ophthalmologic examination in the age of 4-10 years and perinatal data assessment for risk factor analysis. Read More

    1 OF 25