Prevalence and correlates of non-adherence to immunosuppressants and to health behaviours in patients after kidney transplantation in Brazil - the ADHERE BRAZIL multicentre study: a cross-sectional study protocol.
- Helady Sanders-Pinheiro,
- Fernando Antonio Basile Colugnati,
- Elisa Oliveira Marsicano,
- Sabina De Geest,
- José Osmar Pestana Medina,
BMC Nephrol 2018 Feb 20;19(1):41. Epub 2018 Feb 20.
Hospital do Rim e Hipertensão, Federal University of São Paulo, São Paulo, Brazil.
Background: Non-adherence to immunosuppressive therapy is a prevalent risk factor for poor clinical and after kidney transplantation (KT), and has contributed to the lack of improvement in long-term graft survival over the past decade. Understanding the multilevel correlates and risk factors of non-adherence is crucial to determine the optimal level for planning interventions, namely at the patient, health care provider, KT centre, and health care system level. Brazil, having the largest public transplantation program in the world and with regional differences regarding access to health services and service implementation, is in a unique position to study this multilevel approach. Read More