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    462 results match your criteria BMC Medical Imaging[Journal]

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    The segmentation of bones in pelvic CT images based on extraction of key frames.
    BMC Med Imaging 2018 May 22;18(1):18. Epub 2018 May 22.
    Department of Biomedical Engineering, Tianjin University, Tianjin, China.
    Background: Bone segmentation is important in computed tomography (CT) imaging of the pelvis, which assists physicians in the early diagnosis of pelvic injury, in planning operations, and in evaluating the effects of surgical treatment. This study developed a new algorithm for the accurate, fast, and efficient segmentation of the pelvis.

    Methods: The proposed method consists of two main parts: the extraction of key frames and the segmentation of pelvic CT images. Read More

    A consistency evaluation of signal-to-noise ratio in the quality assessment of human brain magnetic resonance images.
    BMC Med Imaging 2018 May 16;18(1):17. Epub 2018 May 16.
    Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
    Background: Quality assessment of medical images is highly related to the quality assurance, image interpretation and decision making. As to magnetic resonance (MR) images, signal-to-noise ratio (SNR) is routinely used as a quality indicator, while little knowledge is known of its consistency regarding different observers.

    Methods: In total, 192, 88, 76 and 55 brain images are acquired using T, T, T and contrast-enhanced T (TC) weighted MR imaging sequences, respectively. Read More

    MPCaD: a multi-scale radiomics-driven framework for automated prostate cancer localization and detection.
    BMC Med Imaging 2018 May 16;18(1):16. Epub 2018 May 16.
    Department of Medical Imaging, University of Toronto and Sunnybrook Research Institute, Toronto, Ontario, Canada.
    Background: Quantitative radiomic features provide a plethora of minable data extracted from multi-parametric magnetic resonance imaging (MP-MRI) which can be used for accurate detection and localization of prostate cancer. While most cancer detection algorithms utilize either voxel-based or region-based feature models, the complexity of prostate tumour phenotype in MP-MRI requires a more sophisticated framework to better leverage available data and exploit a priori knowledge in the field.

    Methods: In this paper, we present MPCaD, a novel Multi-scale radiomics-driven framework for Prostate Cancer Detection and localization which leverages radiomic feature models at different scales as well as incorporates a priori knowledge of the field. Read More

    In silico simulation of liver crack detection using ultrasonic shear wave imaging.
    BMC Med Imaging 2018 May 16;18(1):15. Epub 2018 May 16.
    College of Science, Liaoning Shihua University, Fushun, People's Republic of China.
    Background: Liver trauma is an important source of morbidity and mortality worldwide. A timely detection and precise evaluation of traumatic liver injury and the bleeding site is necessary. There is a need to develop better imaging modalities of hepatic injuries to increase the sensitivity of ultrasonic imaging techniques for sites of hemorrhage caused by cracks. Read More

    Contrast-enhanced ultrasonography of the pancreas shows impaired perfusion in pancreas insufficient cystic fibrosis patients.
    BMC Med Imaging 2018 May 15;18(1):14. Epub 2018 May 15.
    Department of Clinical Medicine, University of Bergen, Bergen, Norway.
    Background: Perfusion assessment of the pancreas is challenging and poorly evaluated. Pancreatic affection is a prevalent feature of cystic fibrosis (CF). Little is known about pancreatic perfusion in CF. Read More

    An automated algorithm for the detection of cortical interruptions and its underlying loss of trabecular bone; a reproducibility study.
    BMC Med Imaging 2018 May 15;18(1):13. Epub 2018 May 15.
    Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Centre, P.O. Box 5800, NL-6202, Maastricht, AZ, the Netherlands.
    Background: We developed a semi-automated algorithm that detects cortical interruptions in finger joints using high-resolution peripheral quantitative computed tomography (HR-pQCT), and extended it with trabecular void volume measurement. In this study we tested the reproducibility of the algorithm using scan/re-scan data.

    Methods: Second and third metacarpophalangeal joints of 21 subjects (mean age 49 (SD 11) years, 17 early rheumatoid arthritis and 4 undifferentiated arthritis, all diagnosed < 1 year ago) were imaged twice by HR-pQCT on the same day with repositioning between scans. Read More

    Utility of routine ultrasonography follow-up after total thyroidectomy in patients with papillary thyroid carcinoma: a single-center study.
    BMC Med Imaging 2018 May 15;18(1):12. Epub 2018 May 15.
    Department of Radiology, Gyeongsang National University School of Medicine and Gyeongsang National University Changwon Hospital, Changwon, 51476, South Korea.
    Background: This study aimed to assess the appropriate number of sessions and interval of routine follow-up ultrasonography (US) in patients who underwent total thyroidectomy for papillary thyroid carcinoma (PTC).

    Methods: Between January 2008 and December 2009, 569 patients underwent total thyroidectomy for PTC. Of the 569 patients, 44 were excluded from the study because of no US follow-up data for the neck (n = 43) or owing to indeterminate tumor recurrence/persistence (n = 1). Read More

    Mammographic density changes in surgical weight loss-an indication for personalized screening.
    BMC Med Imaging 2018 May 9;18(1):10. Epub 2018 May 9.
    Division of Breast Surgery, Columbia University Medical Center/New York Presbyterian, 161 Fort Washington Ave 10th floor, New York, NY, 10032, USA.
    Background: Obesity and high radiologic breast density independently increase breast cancer risk. We evaluated the effect of surgical weight loss on mammographic density (MD).

    Methods: Patients undergoing bariatric surgery and screening mammography (MG) were identified, data regarding demographics, comorbidities, calculated and genetic breast cancer risk was collected. Read More

    Quantification of FDG-PET/CT with delayed imaging in patients with newly diagnosed recurrent breast cancer.
    BMC Med Imaging 2018 May 9;18(1):11. Epub 2018 May 9.
    Department of Nuclear Medicine, University Hospital, Sdr. Boulevard 29, 5000, Odense C, Denmark.
    Background: Several studies have shown the advantage of delayed-time-point imaging with 18F-FDG-PET/CT to distinguish malignant from benign uptake. This may be relevant in cancer diseases with low metabolism, such as breast cancer. We aimed at examining the change in SUV from 1 h (1h) to 3 h (3h) time-point imaging in local and distant lesions in patients with recurrent breast cancer. Read More

    Automatic brain tissue segmentation based on graph filter.
    BMC Med Imaging 2018 May 9;18(1). Epub 2018 May 9.
    Laboratory of Image Science and Technology, Key Laboratory of Computer Network and Information Integration, School of Computer Science and Engineering, Southeast University, Nanjing, People's Republic of China.
    Background: Accurate segmentation of brain tissues from magnetic resonance imaging (MRI) is of significant importance in clinical applications and neuroscience research. Accurate segmentation is challenging due to the tissue heterogeneity, which is caused by noise, bias filed and partial volume effects.

    Methods: To overcome this limitation, this paper presents a novel algorithm for brain tissue segmentation based on supervoxel and graph filter. Read More

    A prospective study to evaluate the intra-individual reproducibility of bone scans for quantitative assessment in patients with metastatic prostate cancer.
    BMC Med Imaging 2018 May 4;18(1). Epub 2018 May 4.
    Department of Clinical Physiology and Nuclear Medicine, Skåne University Hospital, Inga Marie Nilssons gata 49, SE-205 02, Malmö, Sweden.
    Background: The Bone Scan Index (BSI) is used to quantitatively assess the total tumour burden in bone scans of patients with metastatic prostate cancer. The clinical utility of BSI has recently been validated as a prognostic imaging biomarker. However, the clinical utility of the on-treatment change in BSI is dependent on the reproducibility of bone scans. Read More

    Joint sparse reconstruction of multi-contrast MRI images with graph based redundant wavelet transform.
    BMC Med Imaging 2018 May 3;18(1). Epub 2018 May 3.
    Department of Electronic Science, Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance, Xiamen University, Xiamen, 361005, China.
    Background: Multi-contrast images in magnetic resonance imaging (MRI) provide abundant contrast information reflecting the characteristics of the internal tissues of human bodies, and thus have been widely utilized in clinical diagnosis. However, long acquisition time limits the application of multi-contrast MRI. One efficient way to accelerate data acquisition is to under-sample the k-space data and then reconstruct images with sparsity constraint. Read More

    Differentiation of orbital lymphoma and idiopathic orbital inflammatory pseudotumor: combined diagnostic value of conventional MRI and histogram analysis of ADC maps.
    BMC Med Imaging 2018 May 2;18(1). Epub 2018 May 2.
    Department of Radiology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
    Background: The overlap of morphological feature and mean ADC value restricted clinical application of MRI in the differential diagnosis of orbital lymphoma and idiopathic orbital inflammatory pseudotumor (IOIP). In this paper, we aimed to retrospectively evaluate the combined diagnostic value of conventional magnetic resonance imaging (MRI) and whole-tumor histogram analysis of apparent diffusion coefficient (ADC) maps in the differentiation of the two lesions.

    Methods: In total, 18 patients with orbital lymphoma and 22 patients with IOIP were included, who underwent both conventional MRI and diffusion weighted imaging before treatment. Read More

    Dental age estimation in southern Chinese population using panoramic radiographs: validation of three population specific reference datasets.
    BMC Med Imaging 2018 Apr 27;18(1). Epub 2018 Apr 27.
    Paediatric Dentistry, School of Dentistry, University of Western Australia, Perth, Australia.
    Background: The accuracy of estimated age should depend on the reference data sets (RDS) from which the maturity scores or Ages of Attainment (AoA) were obtained. This study aimed to test the accuracy of age estimation from three different population specific dental reference datasets (RDS).

    Methods: Two hundred and sixty six dental panoramic radiographs of subjects belonging to southern Chinese ethnicity were scored and dental age (DA) was estimated from three reference datasets: French-Canadian, United Kingdom (UK) Caucasian and southern Chinese. Read More

    Daily routine versus on-demand chest radiograph policy and practice in adult ICU patients- clinicians' perspective.
    BMC Med Imaging 2018 Apr 3;18(1). Epub 2018 Apr 3.
    Department of Health Systems and Quality Management, College of Public Health and Health Informatics, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
    Background: Chest radiographs are taken daily as a part of routine investigations in Intensive care unit (ICU) patients. They are less effective and unlikely to alter the management of the majority of these patients compared to the radiographs obtained when indicated. According to the American College of Radiology (ACR) Appropriateness criteria, only selective ordering of chest radiographs is recommended, including elderly or high risk patients. Read More

    Incidental finding of large pneumothorax on Cardiac MR scan.
    BMC Med Imaging 2018 02 12;18(1). Epub 2018 Feb 12.
    Centre for Cardiovascular Sciences, Chancellors Building, University of Edinburgh, 49 Little France Crescent, Edinburgh, EH16 4SB, UK.
    Background: We believe this is the first case report of a pneumothorax being identified using cardiac magnetic resonance imaging. This case also illustrates the haemodynamic effect a large pneumothorax can have on right ventricular filling in diastole.

    Case Presentation: A 26-year-old attended for an interval follow up Cardiac Magnetic Resonance (CMR) of his thoracic aorta after a thoracic co-arctation repair aged 3. Read More

    Investigations of organ and effective doses of abdominal cone-beam computed tomography during transarterial chemoembolization using Monte Carlo simulation.
    BMC Med Imaging 2018 02 5;18(1). Epub 2018 Feb 5.
    Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou, 5 Fushing Street, Kweishan, Taoyuan, 333, Taiwan, Republic of China.
    Background: To investigate the organ dose, effective dose (ED), conversion factor, and the C-arm rotation angle effects on dose variations of abdominal C-arm cone-beam computed tomography (CBCT) during transarterial chemoembolization (TACE).

    Methods: The organ doses and EDs for abdominal C-arm CBCT were retrospectively calculated according to a Monte Carlo technique for 80 patients. Dose variations from projections, ED to dose-area product (DAP) ratios, and effects of body mass index (BMI) on the ED and ED to DAP ratios were also analyzed. Read More

    Systemic air embolism after percutaneous computed tomography-guided lung biopsy due to a kink in the coaxial biopsy system: a case report.
    BMC Med Imaging 2018 01 27;18(1). Epub 2018 Jan 27.
    School of Medicine, Tzu Chi University, Hualien, Taiwan.
    Background: Systemic air embolism is a rare but potentially life-threatening complication of percutaneous computed tomography (CT)-guided lung biopsy. The incidence might be underestimated because of failure to diagnose this adverse event in asymptomatic patients; early recognition is difficult.

    Case Presentation: We report the case of a 73-year-old man with systemic air embolism, a complication of percutaneous CT-guided lung biopsy, due to a kink in the coaxial biopsy system. Read More

    Cardiovascular magnetic resonance in the evaluation of heart valve disease.
    BMC Med Imaging 2017 12 29;17(1):67. Epub 2017 Dec 29.
    Department of Cardiovascular Sciences, University of Leicester and the NIHR Biomedical Research Centre, Glenfield Hospital, Groby Road, Leicester, UK.
    Background: Over the last 25 years, cardiovascular magnetic resonance imaging (CMR) has emerged as an alternative to echocardiography for assessment of valvular heart disease (VHD). Although echo remains the first-line imaging modality for the assessment of patients with VHD, CMR can now provide a comprehensive assessment in many instances. Using a combination of techniques, CMR provides information on valve anatomy and enables quantitative analysis of the severity of the valve lesion. Read More

    The morphology of maxillary first and second molars analyzed by cone-beam computed tomography in a polish population.
    BMC Med Imaging 2017 12 29;17(1):68. Epub 2017 Dec 29.
    Department of Endodontics, Medical University of Lodz, Poland, Pomorska 251, 92-213, Lodz, Poland.
    Background: The success of endodontic treatment is greatly affected by the location of the root canals. The purpose of this study was to evaluate the root and canal morphology of permanent maxillary first and second molars in a Polish population using cone-beam computed tomography scanning.

    Methods: Cone-beam computed tomography (CBCT) scans of maxillary first and second molars the maxilla were examined. Read More

    MRI texture analysis in differentiating luminal A and luminal B breast cancer molecular subtypes - a feasibility study.
    BMC Med Imaging 2017 12 29;17(1):69. Epub 2017 Dec 29.
    Department of Radiology, University of Turku and Turku University Hospital, Turku, Finland.
    Background: The aim of this study was to use texture analysis (TA) of breast magnetic resonance (MR) images to assist in differentiating estrogen receptor (ER) positive breast cancer molecular subtypes.

    Methods: Twenty-seven patients with histopathologically proven invasive ductal breast cancer were selected in preliminary study. Tumors were classified into molecular subtypes: luminal A (ER-positive and/or progesterone receptor (PR)-positive, human epidermal growth factor receptor type 2 (HER2) -negative, proliferation marker Ki-67 < 20 and low grade (I)) and luminal B (ER-positive and/or PR-positive, HER2-positive or HER2-negative with high Ki-67 ≥ 20 and higher grade (II or III)). Read More

    Superb microvascular imaging (SMI) compared with conventional ultrasound for evaluating thyroid nodules.
    BMC Med Imaging 2017 12 28;17(1):65. Epub 2017 Dec 28.
    Department of Ultrasonography, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China.
    Background: Superb microvascular imaging (SMI) for depiction of microvascular flow in thyroid nodules was compared with color/power Doppler imaging (CDI/PDI) and contrast-enhanced ultrasonography (CEUS). In addition, the diagnostic performance of conventional ultrasound combined with SMI for differentiating benign and malignant thyroid nodules was evaluated.

    Methods: Preoperative conventional ultrasound consisting of gray-scale ultrasonography and CDI/PDI, followed by SMI and CEUS, was used to record 52 thyroid nodules. Read More

    Follow-up of iatrogenic aorto-coronary "Dunning" dissections by cardiac computed tomography imaging.
    BMC Med Imaging 2017 12 21;17(1):64. Epub 2017 Dec 21.
    First Department of Medicine, University Medical Centre Mannheim, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
    Background: Iatrogenic aorto-coronary dissections following percutaneous coronary interventions (PCI) represent a rare but potentially life threatening complication. This restrospective and observational study aims to describe our in-house experience for timely diagnostics and therapy including cardiovascular imaging to follow-up securely high-risk patients with Dunning dissections.

    Methods: Dunning dissections (DD) occurred during clinical routine PCIs, which were indicated according to current ESC guidelines. Read More

    Ultra-high b-value diffusion-weighted imaging features of the prostatic leiomyoma-case report.
    BMC Med Imaging 2017 Dec 20;17(1):63. Epub 2017 Dec 20.
    Department of Radiology, Chinese PLA General Hospital, Fuxing Road NO.28, Box 100853, Beijing, China.
    Background: Leiomyoma of the prostate is a rare benign tumor arising from smooth muscle fibers. Most cases are incidental findings observed during pathological examinations after resection of the prostate. To the best of our knowledge, only few studies have reported the conventional magnetic resonance imaging (MRI) findings of such tumors; however, no reports have described the ultra-high b-value diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) findings of prostatic leiomyomas. Read More

    Improving the evaluation of cardiac function in rats at 7T with denoising filters: a comparison study.
    BMC Med Imaging 2017 Dec 19;17(1):62. Epub 2017 Dec 19.
    Le2I, Faculté de Médecine, Université Bourgogne Franche-Comté, 7 Bld Jeanne d'Arc, 21079, Dijon Cedex, BP 87900, France.
    Background: We investigate the use of different denoising filters on low signal-to-noise ratio cardiac images of the rat heart acquired with a birdcage volume coil at 7T. Accuracy and variability of cardiac function parameters were measured from manual segmentation of rat heart images with and without filtering.

    Methods: Ten rats were studied using a 7T Varian system. Read More

    Computed tomography scan based prediction of the vulnerable carotid plaque.
    BMC Med Imaging 2017 Dec 13;17(1):61. Epub 2017 Dec 13.
    Department of Cardiothoracic and Vascular Surgery, Odense University Hospital, Sdr. Boulevard 29, 5000, Odense C, Denmark.
    Background: Primary to validate a commercial semi-automated computed tomography angiography (CTA) -software for vulnerable plaque detection compared to histology of carotid endarterectomy (CEA) specimens and secondary validating calcifications scores by in vivo CTA with ex vivo non-contrast enhanced computed tomography (NCCT).

    Methods: From January 2014 to October 2016 53 patients were included retrospectively, using a cross-sectional design. All patients underwent both CTA and CEA. Read More

    Lesion based diagnostic performance of dual phase Tc-MIBI SPECT/CT imaging and ultrasonography in patients with secondary hyperparathyroidism.
    BMC Med Imaging 2017 Dec 12;17(1):60. Epub 2017 Dec 12.
    Department of Nuclear Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, 160 Pujian Road, Pudong District, Shanghai, 200127, China.
    Background: We aimed to evaluate the diagnostic performance of Tc-MIBI SPECT/CT and ultrasonography in patients with secondary hyperparathyroidism (SHPT), and explored the factors that affect the diagnostic performance.

    Methods: Tc-MIBI SPECT/CT and ultrasonography were performed in 50 patients with SHPT within 1 month before they underwent surgery. Imaging results were confirmed by the pathology. Read More

    Testing of the assisting software for radiologists analysing head CT images: lessons learned.
    BMC Med Imaging 2017 Dec 11;17(1):59. Epub 2017 Dec 11.
    Optoelectronics and Measurement Techniques Unit, University of Oulu, PO Box 4500, 90014, Oulu, Finland.
    Background: Assessing a plan for user testing and evaluation of the assisting software developed for radiologists.

    Methods: Test plan was assessed in experimental testing, where users performed reporting on head computed tomography studies with the aid of the software developed. The user testing included usability tests, questionnaires, and interviews. Read More

    Radiographic features of Ollier's disease - two case reports.
    BMC Med Imaging 2017 Dec 2;17(1):58. Epub 2017 Dec 2.
    Orthopedic Department of French Medical Institute for Mothers and Children (FMIC), Kabul, Afghanistan.
    Background: Ollier's disease is a non-hereditary, benign bone tumor which is usually characterized by presence of multiple radiolucent lesions (enchondromas) in the metaphysis of long bones with unilateral predominance. The disease is a rare clinical entity with 1/100000 occurrence in early childhood. Patients mostly present with multiple hard swellings and deformity of the tubular bones specially hands and feet with leg discrepancy and pathologic fractures. Read More

    Nonlocal total variation based on symmetric Kullback-Leibler divergence for the ultrasound image despeckling.
    BMC Med Imaging 2017 Nov 28;17(1):57. Epub 2017 Nov 28.
    Guangdong Provincial Key Laboratory of Medical Image Processing, School of Biomedical Engineering, Southern Medical University, Guangzhou, 510515, People's Republic of China.
    Background: Ultrasound imaging is safer than other imaging modalities, because it is noninvasive and nonradiative. Speckle noise degrades the quality of ultrasound images and has negative effects on visual perception and diagnostic operations.

    Methods: In this paper, a nonlocal total variation (NLTV) method for ultrasonic speckle reduction is proposed. Read More

    Contribution of diffusion-weighted imaging to conventional MRI for detection of haemorrhagic infarction in ovary torsion.
    BMC Med Imaging 2017 Nov 22;17(1):56. Epub 2017 Nov 22.
    Department of Radiology, Muş State Hospital, Muş, Turkey.
    Background: To assess the role of DWI in differentiation haemorrhagic ovary infarction from non-haemorrhagic one.

    Methods: For this prospectively designed study, of 117 female patients who presented with acute lower quadrant pain and underwent MRI for suspicion of ovary torsion, results of only 29 patients (mean age, 24.7; SD, ±5. Read More

    Computer-aided evaluation of inflammatory changes over time on MRI of the spine in patients with suspected axial spondyloarthritis: a feasibility study.
    BMC Med Imaging 2017 Sep 19;17(1):55. Epub 2017 Sep 19.
    Department of Radiology, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.
    Background: Evaluating inflammatory changes over time on MR images of the spine in patients with suspected axial Spondyloarthritis (axSpA) can be a labor-intensive task, requiring readers to manually search for and perceptually align a set of vertebrae between two scans. The purpose of this study was to assess the feasibility of computer-aided (CA) evaluation of such inflammatory changes in a framework where scans from two time points are fused into a single color-encoded image integrated into an interactive scoring tool.

    Methods: For 30 patients from the SPondyloArthritis Caught Early (SPACE) cohort (back pain ≥ 3 months, ≤ 2 years, onset < 45 years), baseline and follow-up MR scans acquired 9-12 months apart were fused into a single color-encoded image through locally-rigid image registration to evaluate inflammatory changes in 23 vertebral units (VUs). Read More

    Case report of hyperglycemic nonketotic chorea with rapid radiological resolution.
    BMC Med Imaging 2017 Sep 12;17(1):54. Epub 2017 Sep 12.
    National hospital, Colombo, Sri Lanka.
    Background: Hemichorea is a rare manifestation of nonketotic hyperglycemia that usually affects elderly Asian women with poor glycemic control. Non-contrast computerized Tomography and T1- weighted Magnetic Resonance Imaging shows characteristic hyperintense basal ganglia lesions.

    Case Presentation: A Fifty-seven year old Sri Lankan female presented with a two-day history of right upper limb chorea. Read More

    Electronic cleansing in computed tomography colonography using AT layer identification with integration of gradient directional second derivative and material fraction model.
    BMC Med Imaging 2017 Sep 4;17(1):53. Epub 2017 Sep 4.
    Machine Intelligence and Multimedia Information Technology laboratory (MIMIT Lab), Department of Mathematics and Computer Science, Faculty of Science, Chulalongkorn University, Payathai Road, Bangkok, 10330, Thailand.
    Background: In computed tomography colonography images, electronic cleansing (EC) is applied to remove opacified residual materials, called fecal-tagging materials (FTM), using positive-contrast tagging agents and laxative to facilitate polyp detection.

    Methods: The proposed EC, EC , integrates the gradient directional second derivative into material fraction model to preserve submerged soft tissue (ST) under FTM. Three-material fraction model is used to remove FTM and artifacts at air-tagging (AT) layers and T-junctions where air, ST, and FTM material meet simultaneously. Read More

    Assessment of thoracic ultrasound in complementary diagnosis and in follow up of community-acquired pneumonia (cap).
    BMC Med Imaging 2017 Aug 31;17(1):52. Epub 2017 Aug 31.
    Unit of Interventional and Diagnostic Ultrasound of Internal Medicine, "Casa Sollievo della Sofferenza" Hospital, IRCCS, San Giovanni Rotondo (FG), Italy.
    Background: Chest X-ray (CXR) is the primary diagnostic tool for community-acquired pneumonia (CAP). Some authors recently proposed that thoracic ultrasound (TUS) could valuably flank or even reliably substitute CXR in the diagnosis and follow-up of CAP. We investigated the clinical utility of TUS in a large sample of patients with CAP, to challenge the hypothesis that it may be a substitute for CXR. Read More

    Cardiovascular magnetic resonance feature tracking in small animals - a preliminary study on reproducibility and sample size calculation.
    BMC Med Imaging 2017 Aug 23;17(1):51. Epub 2017 Aug 23.
    Department of Internal Medicine / Cardiology, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.
    Background: Cardiovascular magnetic resonance feature tracking (CMR-FT) is a novel tissue tracking technique developed for noninvasive assessment of myocardial motion and deformation. This preliminary study aimed to evaluate the observer's reproducibility of CMR-FT in a small animal (mouse) model and define sample size calculation for future trials.

    Methods: Six C57BL/6 J mice were selected from the ongoing experimental mouse model onsite and underwent CMR with a 3 Tesla small animal MRI scanner. Read More

    Diffusion tensor MR imaging characteristics of cerebral white matter development in fetal pigs.
    BMC Med Imaging 2017 Aug 22;17(1):50. Epub 2017 Aug 22.
    Department of Radiology, Shengjing Hospital, China Medical University, Shenyang, 110004, People's Republic of China.
    Background: The purpose of this study was to investigate the anisotropic features of fetal pig cerebral white matter (WM) development by magnetic resonance diffusion tensor imaging, and to evaluate the developmental status of cerebral WM in different anatomical sites at different times.

    Methods: Fetal pigs were divided into three groups according to gestational age: E69 (n = 8), E85 (n = 11), and E114 (n = 6). All pigs were subjected to conventional magnetic resonance imaging (MRI) and diffusion tensor imaging using a GE Signa 3. Read More

    Survey of practitioners' competency for diagnosis of acute diseases manifest on chest X-ray.
    BMC Med Imaging 2017 Aug 18;17(1):49. Epub 2017 Aug 18.
    Department of Radiology, Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
    Background: Chest X-ray (CXR) is a common imaging modality that could impact immediate decision-making for acute chest pathologies. We sought to examine the non-radiologists proficiency of diagnosing acute pathologies manifest on CXR.

    Methods: We selected 9 clinical vignettes, each associated with a CXR, wherein only a single acute chest pathology was manifest. Read More

    Alterations in resting-state functional connectivity of the default mode network in amnestic mild cognitive impairment: an fMRI study.
    BMC Med Imaging 2017 Aug 16;17(1):48. Epub 2017 Aug 16.
    College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, China.
    Background: Amnestic mild cognitive impairment (aMCI) is characterized by cognitive functional decline, especially in memory. Resting-state functional magnetic resonance imaging (fMRI) has been widely used in neuroimaging studies that explore alterations between patients and normal individuals to elucidate the pathological mechanisms of different diseases. The current study was performed to investigate alterations in the functional connectivity of the default mode network (DMN) in aMCI patients compared to healthy elderly controls, as well as further define the association between neurological alterations and memory function. Read More

    Detection of articular perforations of the proximal humerus fracture using a mobile 3D image intensifier - a cadaver study.
    BMC Med Imaging 2017 Aug 1;17(1):47. Epub 2017 Aug 1.
    Department of Orthopedics, Trauma and Plastic Surgery, University of Leipzig, Liebigstrasse 20, 04103, Leipzig, Germany.
    Background: The purpose of this study was to investigate the accuracy of perforation detection with multiplanar reconstructions using a mobile 3D image intensifier.

    Methods: In 12 paired human humeri, K-wires perforating the subchondral bone and placed just below the cartilage level were directed toward five specific regions in the humeral head. Image acquisition was initiated by a fluoroscopy scan. Read More

    The value of Tc-methylene diphosphonate single photon emission computed tomography/computed tomography in diagnosis of fibrous dysplasia.
    BMC Med Imaging 2017 Jul 24;17(1):46. Epub 2017 Jul 24.
    Department of Nuclear Medicine, Affiliated Cancer Hospital&Institute of Guangzhou Medical University, 78 Hengzhigang Road, Guangzhou, 510095, Guangdong province, People's Republic of China.
    Background: Fibrous dysplasia (FD) is a rare benign bone disorder in which the normal bone is replaced by immature fibro-osseous tissue. However, some case reports have reported that FD showed significantly increased Tc-methylene diphosphonate (Tc-MDP) uptake on whole-body bone scintigraphy (WBS), which may mimic bone metastasis or skeletal involvement of the patients with known cancer. Thus, the purpose of present study is to observe the reliable characteristics and usefulness of single photon emission computed tomography/computed tomography (SPECT/CT) for the diagnosis of FD. Read More

    Efficacy of sellar opening in the pituitary adenoma resection of transsphenoidal surgery influences the degree of tumor resection.
    BMC Med Imaging 2017 Jul 24;17(1):45. Epub 2017 Jul 24.
    Department of Neurosurgery, Fuzhou General Hospital, Fujian Medical University, No. 156 Xi'erhuanbei Road, Fuzhou, 350025, People's Republic of China.
    Background: Endonasal transsphenoidal microsurgery is often adopted in the resection of pituitary adenoma, and has showed satisfactory treatment and minor injuries. It is important to accurately localize sellar floor and properly incise the bone and dura matter.

    Methods: Fifty-one patients with pituitary adenoma undergoing endonasal transsphenoidal microsurgery were included in the present study. Read More

    Evaluation of left atrial volume and function using single-beat real-time three-dimensional echocardiography in atrial fibrillation patients.
    BMC Med Imaging 2017 Jul 21;17(1):44. Epub 2017 Jul 21.
    Department of Echocardiography, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No.100 Hai Ning Road, Shanghai, 200080, China.
    Background: This study was aimed to evaluate the feasibility and accuracy of real-time three-dimensional echocardiography (RT-3DE) measurement of left atrial (LA) volume and function in comparison with two-dimensional echocardiography (2DE) measurements in atrial fibrillation (AF) patients.

    Methods: A total of 50 pairs of AF patients and healthy controls were enrolled in this study. Indexed LA end-diastole volume (ILAEDV) and indexed LA end-systolic volume (ILAESV), as well as LA function indices such as segmental LA ejection fraction (LAEF), were assessed using 2DE Simpson's method and the RT-3DE method. Read More

    Iodine concentration calculated by dual-energy computed tomography (DECT) as a functional parameter to evaluate thyroid metabolism in patients with hyperthyroidism.
    BMC Med Imaging 2017 Jul 19;17(1):43. Epub 2017 Jul 19.
    Department of Diagnostic Radiology and Nuclear Medicine, Gunma University Graduate School of Medicine, Faculty of Medicine, 3-39-22, Showa, Maebashi, Gunma, 371-8511, Japan.
    Background: Thyroid function in patients with Grave's disease is usually evaluated by thyroid scintigraphy with radioactive iodine. Recently, dual-energy computed tomography (DECT) with two different energy X-rays can calculate iodine concentrations and can be applied for iodine measurements in thyroid glands. This study aimed to assess the potential use of DECT for the functional assessment of the thyroid gland. Read More

    Texture-based classification of different single liver lesion based on SPAIR T2W MRI images.
    BMC Med Imaging 2017 Jul 13;17(1):42. Epub 2017 Jul 13.
    Shandong Cancer Hospital affiliated to Shandong University, Shandong Academy of Medical Sciences, Jinan, Shandong, China.
    Background: To assess the feasibility of texture analysis (TA) based on spectral attenuated inversion-recovery T2 weighted magnetic resonance imaging (SPAIR T2W-MRI) for the classification of hepatic hemangioma (HH), hepatic metastases (HM) and hepatocellular carcinoma (HCC).

    Methods: The SPAIR T2W-MRI data of 162 patients with HH (n=55), HM (n=67) and HCC (n=40) were retrospectively analyzed. We used two independent cohorts for training (n = 112 patients) and validation (n = 50 patients). Read More

    The value of ultrasound-guided biopsy of fluorodeoxy-glucose positron emission tomography (FDG-PET)-positive supraclavicular lymph nodes in patients with suspected lung cancer.
    BMC Med Imaging 2017 Jul 11;17(1):41. Epub 2017 Jul 11.
    Department of Radiology and Nuclear Medicine, Cantonal Hospital, Spitalstrasse 13, 6000, Lucerne, Switzerland.
    Background: Accurate lymph node staging is essential for adequate prognostication and therapy planning in patients with non-small cell lung cancer (NSCLC). FDG-PET/CT is a sensitive tool for the detection of metastases, including non-palpable supraclavicular lymph node (SCLN) metastases. Histological proof of metastatic spread and mutation analysis is crucial for optimal staging and therapy. Read More

    Prospective evaluation of computer-assisted analysis of skeletal lesions for the staging of prostate cancer.
    BMC Med Imaging 2017 Jul 10;17(1):40. Epub 2017 Jul 10.
    Department of Nuclear Medicine, Clinical Cancer Research Center, Aalborg University Hospital, Hobrovej 18-22, DK-9000, Aalborg, Denmark.
    Background: The purpose of this study was to compare the agreement of the bone scan index (BSI) using EXINI Bone versus experts' readings in the initial staging for bone metastasis in prostate cancer. In addition, the diagnostic outcome was assessed in a large subset of patients where a true reference for metastases could be determined based on clinical and biochemical follow-up and/or supplementary imaging.

    Methods: A total of 342 patients had a bone scintigraphy as part of routine staging for prostate cancer. Read More

    Microbubbles in macrocysts - Contrast-enhanced ultrasound assisted sclerosant therapy of a congenital macrocystic lymphangioma: a case report.
    BMC Med Imaging 2017 Jul 6;17(1):39. Epub 2017 Jul 6.
    Department of Pediatrics and Adolescent Medicine, University Hospital of Erlangen, Loschgestrasse 15, D-91054, Erlangen, Germany.
    Background: Congenital cystic lymphangiomas are benign malformations due to a developmental disorder of lymphatic vessels. Besides surgical excision, sclerosant therapy of these lesions by intracavitary injection of OK-432 (Picibanil®), a lyophilized mixture of group A Streptococcus pyogenes, is a common therapeutical option. For an appropriate application of OK-432, a detailed knowledge about the structure and composition of the congenital cystic lymphangioma is essential. Read More

    CT texture features are associated with overall survival in pancreatic ductal adenocarcinoma - a quantitative analysis.
    BMC Med Imaging 2017 Jun 19;17(1):38. Epub 2017 Jun 19.
    Department of Medical Imaging and Sunnybrook Research Institute, Sunnybrook Health Sciences Center, University of Toronto, 2075 Bayview Ave., Room Rm AG 46, Toronto, M4N 3 M5, ON, Canada.
    Background: To assess whether CT-derived texture features predict survival in patients undergoing resection for pancreatic ductal adenocarcinoma (PDAC).

    Methods: Thirty patients with pre-operative CT from 2007 to 2012 for PDAC were included. Tumor size and five texture features namely uniformity, entropy, dissimilarity, correlation, and inverse difference normalized were calculated. Read More

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