Search our Database of Scientific Publications and Authors

I’m looking for a

    444 results match your criteria BMC Medical Imaging[Journal]

    1 OF 9

    Cardiovascular magnetic resonance in the evaluation of heart valve disease.
    BMC Med Imaging 2017 Dec 29;17(1):67. Epub 2017 Dec 29.
    Department of Cardiovascular Sciences, University of Leicester and the NIHR Biomedical Research Centre, Glenfield Hospital, Groby Road, Leicester, UK.
    Background: Over the last 25 years, cardiovascular magnetic resonance imaging (CMR) has emerged as an alternative to echocardiography for assessment of valvular heart disease (VHD). Although echo remains the first-line imaging modality for the assessment of patients with VHD, CMR can now provide a comprehensive assessment in many instances. Using a combination of techniques, CMR provides information on valve anatomy and enables quantitative analysis of the severity of the valve lesion. Read More

    The morphology of maxillary first and second molars analyzed by cone-beam computed tomography in a polish population.
    BMC Med Imaging 2017 Dec 29;17(1):68. Epub 2017 Dec 29.
    Department of Endodontics, Medical University of Lodz, Poland, Pomorska 251, 92-213, Lodz, Poland.
    Background: The success of endodontic treatment is greatly affected by the location of the root canals. The purpose of this study was to evaluate the root and canal morphology of permanent maxillary first and second molars in a Polish population using cone-beam computed tomography scanning.

    Methods: Cone-beam computed tomography (CBCT) scans of maxillary first and second molars the maxilla were examined. Read More

    MRI texture analysis in differentiating luminal A and luminal B breast cancer molecular subtypes - a feasibility study.
    BMC Med Imaging 2017 Dec 29;17(1):69. Epub 2017 Dec 29.
    Department of Radiology, University of Turku and Turku University Hospital, Turku, Finland.
    Background: The aim of this study was to use texture analysis (TA) of breast magnetic resonance (MR) images to assist in differentiating estrogen receptor (ER) positive breast cancer molecular subtypes.

    Methods: Twenty-seven patients with histopathologically proven invasive ductal breast cancer were selected in preliminary study. Tumors were classified into molecular subtypes: luminal A (ER-positive and/or progesterone receptor (PR)-positive, human epidermal growth factor receptor type 2 (HER2) -negative, proliferation marker Ki-67 < 20 and low grade (I)) and luminal B (ER-positive and/or PR-positive, HER2-positive or HER2-negative with high Ki-67 ≥ 20 and higher grade (II or III)). Read More

    Superb microvascular imaging (SMI) compared with conventional ultrasound for evaluating thyroid nodules.
    BMC Med Imaging 2017 Dec 28;17(1):65. Epub 2017 Dec 28.
    Department of Ultrasonography, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China.
    Background: Superb microvascular imaging (SMI) for depiction of microvascular flow in thyroid nodules was compared with color/power Doppler imaging (CDI/PDI) and contrast-enhanced ultrasonography (CEUS). In addition, the diagnostic performance of conventional ultrasound combined with SMI for differentiating benign and malignant thyroid nodules was evaluated.

    Methods: Preoperative conventional ultrasound consisting of gray-scale ultrasonography and CDI/PDI, followed by SMI and CEUS, was used to record 52 thyroid nodules. Read More

    Follow-up of iatrogenic aorto-coronary "Dunning" dissections by cardiac computed tomography imaging.
    BMC Med Imaging 2017 Dec 21;17(1):64. Epub 2017 Dec 21.
    First Department of Medicine, University Medical Centre Mannheim, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
    Background: Iatrogenic aorto-coronary dissections following percutaneous coronary interventions (PCI) represent a rare but potentially life threatening complication. This restrospective and observational study aims to describe our in-house experience for timely diagnostics and therapy including cardiovascular imaging to follow-up securely high-risk patients with Dunning dissections.

    Methods: Dunning dissections (DD) occurred during clinical routine PCIs, which were indicated according to current ESC guidelines. Read More

    Ultra-high b-value diffusion-weighted imaging features of the prostatic leiomyoma-case report.
    BMC Med Imaging 2017 Dec 20;17(1):63. Epub 2017 Dec 20.
    Department of Radiology, Chinese PLA General Hospital, Fuxing Road NO.28, Box 100853, Beijing, China.
    Background: Leiomyoma of the prostate is a rare benign tumor arising from smooth muscle fibers. Most cases are incidental findings observed during pathological examinations after resection of the prostate. To the best of our knowledge, only few studies have reported the conventional magnetic resonance imaging (MRI) findings of such tumors; however, no reports have described the ultra-high b-value diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) findings of prostatic leiomyomas. Read More

    Improving the evaluation of cardiac function in rats at 7T with denoising filters: a comparison study.
    BMC Med Imaging 2017 Dec 19;17(1):62. Epub 2017 Dec 19.
    Le2I, Faculté de Médecine, Université Bourgogne Franche-Comté, 7 Bld Jeanne d'Arc, 21079, Dijon Cedex, BP 87900, France.
    Background: We investigate the use of different denoising filters on low signal-to-noise ratio cardiac images of the rat heart acquired with a birdcage volume coil at 7T. Accuracy and variability of cardiac function parameters were measured from manual segmentation of rat heart images with and without filtering.

    Methods: Ten rats were studied using a 7T Varian system. Read More

    Computed tomography scan based prediction of the vulnerable carotid plaque.
    BMC Med Imaging 2017 Dec 13;17(1):61. Epub 2017 Dec 13.
    Department of Cardiothoracic and Vascular Surgery, Odense University Hospital, Sdr. Boulevard 29, 5000, Odense C, Denmark.
    Background: Primary to validate a commercial semi-automated computed tomography angiography (CTA) -software for vulnerable plaque detection compared to histology of carotid endarterectomy (CEA) specimens and secondary validating calcifications scores by in vivo CTA with ex vivo non-contrast enhanced computed tomography (NCCT).

    Methods: From January 2014 to October 2016 53 patients were included retrospectively, using a cross-sectional design. All patients underwent both CTA and CEA. Read More

    Lesion based diagnostic performance of dual phase 99mTc-MIBI SPECT/CT imaging and ultrasonography in patients with secondary hyperparathyroidism.
    BMC Med Imaging 2017 Dec 12;17(1):60. Epub 2017 Dec 12.
    Department of Nuclear Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, 160 Pujian Road, Pudong District, Shanghai, 200127, China.
    Background: We aimed to evaluate the diagnostic performance of 99mTc-MIBI SPECT/CT and ultrasonography in patients with secondary hyperparathyroidism (SHPT), and explored the factors that affect the diagnostic performance.

    Methods: 99mTc-MIBI SPECT/CT and ultrasonography were performed in 50 patients with SHPT within 1 month before they underwent surgery. Imaging results were confirmed by the pathology. Read More

    Testing of the assisting software for radiologists analysing head CT images: lessons learned.
    BMC Med Imaging 2017 Dec 11;17(1):59. Epub 2017 Dec 11.
    Optoelectronics and Measurement Techniques Unit, University of Oulu, PO Box 4500, 90014, Oulu, Finland.
    Background: Assessing a plan for user testing and evaluation of the assisting software developed for radiologists.

    Methods: Test plan was assessed in experimental testing, where users performed reporting on head computed tomography studies with the aid of the software developed. The user testing included usability tests, questionnaires, and interviews. Read More

    Radiographic features of Ollier's disease - two case reports.
    BMC Med Imaging 2017 Dec 2;17(1):58. Epub 2017 Dec 2.
    Orthopedic Department of French Medical Institute for Mothers and Children (FMIC), Kabul, Afghanistan.
    Background: Ollier's disease is a non-hereditary, benign bone tumor which is usually characterized by presence of multiple radiolucent lesions (enchondromas) in the metaphysis of long bones with unilateral predominance. The disease is a rare clinical entity with 1/100000 occurrence in early childhood. Patients mostly present with multiple hard swellings and deformity of the tubular bones specially hands and feet with leg discrepancy and pathologic fractures. Read More

    Nonlocal total variation based on symmetric Kullback-Leibler divergence for the ultrasound image despeckling.
    BMC Med Imaging 2017 Nov 28;17(1):57. Epub 2017 Nov 28.
    Guangdong Provincial Key Laboratory of Medical Image Processing, School of Biomedical Engineering, Southern Medical University, Guangzhou, 510515, People's Republic of China.
    Background: Ultrasound imaging is safer than other imaging modalities, because it is noninvasive and nonradiative. Speckle noise degrades the quality of ultrasound images and has negative effects on visual perception and diagnostic operations.

    Methods: In this paper, a nonlocal total variation (NLTV) method for ultrasonic speckle reduction is proposed. Read More

    Contribution of diffusion-weighted imaging to conventional MRI for detection of haemorrhagic infarction in ovary torsion.
    BMC Med Imaging 2017 Nov 22;17(1):56. Epub 2017 Nov 22.
    Department of Radiology, Muş State Hospital, Muş, Turkey.
    Background: To assess the role of DWI in differentiation haemorrhagic ovary infarction from non-haemorrhagic one.

    Methods: For this prospectively designed study, of 117 female patients who presented with acute lower quadrant pain and underwent MRI for suspicion of ovary torsion, results of only 29 patients (mean age, 24.7; SD, ±5. Read More

    Computer-aided evaluation of inflammatory changes over time on MRI of the spine in patients with suspected axial spondyloarthritis: a feasibility study.
    BMC Med Imaging 2017 Sep 19;17(1):55. Epub 2017 Sep 19.
    Department of Radiology, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.
    Background: Evaluating inflammatory changes over time on MR images of the spine in patients with suspected axial Spondyloarthritis (axSpA) can be a labor-intensive task, requiring readers to manually search for and perceptually align a set of vertebrae between two scans. The purpose of this study was to assess the feasibility of computer-aided (CA) evaluation of such inflammatory changes in a framework where scans from two time points are fused into a single color-encoded image integrated into an interactive scoring tool.

    Methods: For 30 patients from the SPondyloArthritis Caught Early (SPACE) cohort (back pain ≥ 3 months, ≤ 2 years, onset < 45 years), baseline and follow-up MR scans acquired 9-12 months apart were fused into a single color-encoded image through locally-rigid image registration to evaluate inflammatory changes in 23 vertebral units (VUs). Read More

    Case report of hyperglycemic nonketotic chorea with rapid radiological resolution.
    BMC Med Imaging 2017 Sep 12;17(1):54. Epub 2017 Sep 12.
    National hospital, Colombo, Sri Lanka.
    Background: Hemichorea is a rare manifestation of nonketotic hyperglycemia that usually affects elderly Asian women with poor glycemic control. Non-contrast computerized Tomography and T1- weighted Magnetic Resonance Imaging shows characteristic hyperintense basal ganglia lesions.

    Case Presentation: A Fifty-seven year old Sri Lankan female presented with a two-day history of right upper limb chorea. Read More

    Electronic cleansing in computed tomography colonography using AT layer identification with integration of gradient directional second derivative and material fraction model.
    BMC Med Imaging 2017 Sep 4;17(1):53. Epub 2017 Sep 4.
    Machine Intelligence and Multimedia Information Technology laboratory (MIMIT Lab), Department of Mathematics and Computer Science, Faculty of Science, Chulalongkorn University, Payathai Road, Bangkok, 10330, Thailand.
    Background: In computed tomography colonography images, electronic cleansing (EC) is applied to remove opacified residual materials, called fecal-tagging materials (FTM), using positive-contrast tagging agents and laxative to facilitate polyp detection.

    Methods: The proposed EC, EC prop , integrates the gradient directional second derivative into material fraction model to preserve submerged soft tissue (ST) under FTM. Three-material fraction model is used to remove FTM and artifacts at air-tagging (AT) layers and T-junctions where air, ST, and FTM material meet simultaneously. Read More

    Assessment of thoracic ultrasound in complementary diagnosis and in follow up of community-acquired pneumonia (cap).
    BMC Med Imaging 2017 Aug 31;17(1):52. Epub 2017 Aug 31.
    Unit of Interventional and Diagnostic Ultrasound of Internal Medicine, "Casa Sollievo della Sofferenza" Hospital, IRCCS, San Giovanni Rotondo (FG), Italy.
    Background: Chest X-ray (CXR) is the primary diagnostic tool for community-acquired pneumonia (CAP). Some authors recently proposed that thoracic ultrasound (TUS) could valuably flank or even reliably substitute CXR in the diagnosis and follow-up of CAP. We investigated the clinical utility of TUS in a large sample of patients with CAP, to challenge the hypothesis that it may be a substitute for CXR. Read More

    Cardiovascular magnetic resonance feature tracking in small animals - a preliminary study on reproducibility and sample size calculation.
    BMC Med Imaging 2017 Aug 23;17(1):51. Epub 2017 Aug 23.
    Department of Internal Medicine / Cardiology, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.
    Background: Cardiovascular magnetic resonance feature tracking (CMR-FT) is a novel tissue tracking technique developed for noninvasive assessment of myocardial motion and deformation. This preliminary study aimed to evaluate the observer's reproducibility of CMR-FT in a small animal (mouse) model and define sample size calculation for future trials.

    Methods: Six C57BL/6 J mice were selected from the ongoing experimental mouse model onsite and underwent CMR with a 3 Tesla small animal MRI scanner. Read More

    Diffusion tensor MR imaging characteristics of cerebral white matter development in fetal pigs.
    BMC Med Imaging 2017 Aug 22;17(1):50. Epub 2017 Aug 22.
    Department of Radiology, Shengjing Hospital, China Medical University, Shenyang, 110004, People's Republic of China.
    Background: The purpose of this study was to investigate the anisotropic features of fetal pig cerebral white matter (WM) development by magnetic resonance diffusion tensor imaging, and to evaluate the developmental status of cerebral WM in different anatomical sites at different times.

    Methods: Fetal pigs were divided into three groups according to gestational age: E69 (n = 8), E85 (n = 11), and E114 (n = 6). All pigs were subjected to conventional magnetic resonance imaging (MRI) and diffusion tensor imaging using a GE Signa 3. Read More

    Survey of practitioners' competency for diagnosis of acute diseases manifest on chest X-ray.
    BMC Med Imaging 2017 Aug 18;17(1):49. Epub 2017 Aug 18.
    Department of Radiology, Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
    Background: Chest X-ray (CXR) is a common imaging modality that could impact immediate decision-making for acute chest pathologies. We sought to examine the non-radiologists proficiency of diagnosing acute pathologies manifest on CXR.

    Methods: We selected 9 clinical vignettes, each associated with a CXR, wherein only a single acute chest pathology was manifest. Read More

    Alterations in resting-state functional connectivity of the default mode network in amnestic mild cognitive impairment: an fMRI study.
    BMC Med Imaging 2017 Aug 16;17(1):48. Epub 2017 Aug 16.
    College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, China.
    Background: Amnestic mild cognitive impairment (aMCI) is characterized by cognitive functional decline, especially in memory. Resting-state functional magnetic resonance imaging (fMRI) has been widely used in neuroimaging studies that explore alterations between patients and normal individuals to elucidate the pathological mechanisms of different diseases. The current study was performed to investigate alterations in the functional connectivity of the default mode network (DMN) in aMCI patients compared to healthy elderly controls, as well as further define the association between neurological alterations and memory function. Read More

    Detection of articular perforations of the proximal humerus fracture using a mobile 3D image intensifier - a cadaver study.
    BMC Med Imaging 2017 Aug 1;17(1):47. Epub 2017 Aug 1.
    Department of Orthopedics, Trauma and Plastic Surgery, University of Leipzig, Liebigstrasse 20, 04103, Leipzig, Germany.
    Background: The purpose of this study was to investigate the accuracy of perforation detection with multiplanar reconstructions using a mobile 3D image intensifier.

    Methods: In 12 paired human humeri, K-wires perforating the subchondral bone and placed just below the cartilage level were directed toward five specific regions in the humeral head. Image acquisition was initiated by a fluoroscopy scan. Read More

    The value of 99mTc-methylene diphosphonate single photon emission computed tomography/computed tomography in diagnosis of fibrous dysplasia.
    BMC Med Imaging 2017 Jul 24;17(1):46. Epub 2017 Jul 24.
    Department of Nuclear Medicine, Affiliated Cancer Hospital&Institute of Guangzhou Medical University, 78 Hengzhigang Road, Guangzhou, 510095, Guangdong province, People's Republic of China.
    Background: Fibrous dysplasia (FD) is a rare benign bone disorder in which the normal bone is replaced by immature fibro-osseous tissue. However, some case reports have reported that FD showed significantly increased 99mTc-methylene diphosphonate (99mTc-MDP) uptake on whole-body bone scintigraphy (WBS), which may mimic bone metastasis or skeletal involvement of the patients with known cancer. Thus, the purpose of present study is to observe the reliable characteristics and usefulness of single photon emission computed tomography/computed tomography (SPECT/CT) for the diagnosis of FD. Read More

    Efficacy of sellar opening in the pituitary adenoma resection of transsphenoidal surgery influences the degree of tumor resection.
    BMC Med Imaging 2017 Jul 24;17(1):45. Epub 2017 Jul 24.
    Department of Neurosurgery, Fuzhou General Hospital, Fujian Medical University, No. 156 Xi'erhuanbei Road, Fuzhou, 350025, People's Republic of China.
    Background: Endonasal transsphenoidal microsurgery is often adopted in the resection of pituitary adenoma, and has showed satisfactory treatment and minor injuries. It is important to accurately localize sellar floor and properly incise the bone and dura matter.

    Methods: Fifty-one patients with pituitary adenoma undergoing endonasal transsphenoidal microsurgery were included in the present study. Read More

    Evaluation of left atrial volume and function using single-beat real-time three-dimensional echocardiography in atrial fibrillation patients.
    BMC Med Imaging 2017 Jul 21;17(1):44. Epub 2017 Jul 21.
    Department of Echocardiography, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No.100 Hai Ning Road, Shanghai, 200080, China.
    Background: This study was aimed to evaluate the feasibility and accuracy of real-time three-dimensional echocardiography (RT-3DE) measurement of left atrial (LA) volume and function in comparison with two-dimensional echocardiography (2DE) measurements in atrial fibrillation (AF) patients.

    Methods: A total of 50 pairs of AF patients and healthy controls were enrolled in this study. Indexed LA end-diastole volume (ILAEDV) and indexed LA end-systolic volume (ILAESV), as well as LA function indices such as segmental LA ejection fraction (LAEF), were assessed using 2DE Simpson's method and the RT-3DE method. Read More

    Iodine concentration calculated by dual-energy computed tomography (DECT) as a functional parameter to evaluate thyroid metabolism in patients with hyperthyroidism.
    BMC Med Imaging 2017 Jul 19;17(1):43. Epub 2017 Jul 19.
    Department of Diagnostic Radiology and Nuclear Medicine, Gunma University Graduate School of Medicine, Faculty of Medicine, 3-39-22, Showa, Maebashi, Gunma, 371-8511, Japan.
    Background: Thyroid function in patients with Grave's disease is usually evaluated by thyroid scintigraphy with radioactive iodine. Recently, dual-energy computed tomography (DECT) with two different energy X-rays can calculate iodine concentrations and can be applied for iodine measurements in thyroid glands. This study aimed to assess the potential use of DECT for the functional assessment of the thyroid gland. Read More

    Texture-based classification of different single liver lesion based on SPAIR T2W MRI images.
    BMC Med Imaging 2017 Jul 13;17(1):42. Epub 2017 Jul 13.
    Shandong Cancer Hospital affiliated to Shandong University, Shandong Academy of Medical Sciences, Jinan, Shandong, China.
    Background: To assess the feasibility of texture analysis (TA) based on spectral attenuated inversion-recovery T2 weighted magnetic resonance imaging (SPAIR T2W-MRI) for the classification of hepatic hemangioma (HH), hepatic metastases (HM) and hepatocellular carcinoma (HCC).

    Methods: The SPAIR T2W-MRI data of 162 patients with HH (n=55), HM (n=67) and HCC (n=40) were retrospectively analyzed. We used two independent cohorts for training (n = 112 patients) and validation (n = 50 patients). Read More

    The value of ultrasound-guided biopsy of fluorodeoxy-glucose positron emission tomography (FDG-PET)-positive supraclavicular lymph nodes in patients with suspected lung cancer.
    BMC Med Imaging 2017 Jul 11;17(1):41. Epub 2017 Jul 11.
    Department of Radiology and Nuclear Medicine, Cantonal Hospital, Spitalstrasse 13, 6000, Lucerne, Switzerland.
    Background: Accurate lymph node staging is essential for adequate prognostication and therapy planning in patients with non-small cell lung cancer (NSCLC). FDG-PET/CT is a sensitive tool for the detection of metastases, including non-palpable supraclavicular lymph node (SCLN) metastases. Histological proof of metastatic spread and mutation analysis is crucial for optimal staging and therapy. Read More

    Prospective evaluation of computer-assisted analysis of skeletal lesions for the staging of prostate cancer.
    BMC Med Imaging 2017 Jul 10;17(1):40. Epub 2017 Jul 10.
    Department of Nuclear Medicine, Clinical Cancer Research Center, Aalborg University Hospital, Hobrovej 18-22, DK-9000, Aalborg, Denmark.
    Background: The purpose of this study was to compare the agreement of the bone scan index (BSI) using EXINI BoneBSI versus experts' readings in the initial staging for bone metastasis in prostate cancer. In addition, the diagnostic outcome was assessed in a large subset of patients where a true reference for metastases could be determined based on clinical and biochemical follow-up and/or supplementary imaging.

    Methods: A total of 342 patients had a bone scintigraphy as part of routine staging for prostate cancer. Read More

    Microbubbles in macrocysts - Contrast-enhanced ultrasound assisted sclerosant therapy of a congenital macrocystic lymphangioma: a case report.
    BMC Med Imaging 2017 Jul 6;17(1):39. Epub 2017 Jul 6.
    Department of Pediatrics and Adolescent Medicine, University Hospital of Erlangen, Loschgestrasse 15, D-91054, Erlangen, Germany.
    Background: Congenital cystic lymphangiomas are benign malformations due to a developmental disorder of lymphatic vessels. Besides surgical excision, sclerosant therapy of these lesions by intracavitary injection of OK-432 (Picibanil®), a lyophilized mixture of group A Streptococcus pyogenes, is a common therapeutical option. For an appropriate application of OK-432, a detailed knowledge about the structure and composition of the congenital cystic lymphangioma is essential. Read More

    CT texture features are associated with overall survival in pancreatic ductal adenocarcinoma - a quantitative analysis.
    BMC Med Imaging 2017 Jun 19;17(1):38. Epub 2017 Jun 19.
    Department of Medical Imaging and Sunnybrook Research Institute, Sunnybrook Health Sciences Center, University of Toronto, 2075 Bayview Ave., Room Rm AG 46, Toronto, M4N 3 M5, ON, Canada.
    Background: To assess whether CT-derived texture features predict survival in patients undergoing resection for pancreatic ductal adenocarcinoma (PDAC).

    Methods: Thirty patients with pre-operative CT from 2007 to 2012 for PDAC were included. Tumor size and five texture features namely uniformity, entropy, dissimilarity, correlation, and inverse difference normalized were calculated. Read More

    Atypical findings of perineural cysts on postmyelographic computed tomography: a case report of intermittent intercostal neuralgia caused by thoracic perineural cysts.
    BMC Med Imaging 2017 Jun 13;17(1):37. Epub 2017 Jun 13.
    Department of Neurosurgery, Tokyo Metropolitan Neurological Hospital, 2-6-1 Musashidai, Fuchu, 1830042, Japan.
    Background: Perineural cysts are sometimes found incidentally with magnetic resonance imaging, and clinical symptoms requiring treatment are rare. Perineural cysts typically exhibit delayed filling with contrast medium on myelography, which is one of the criteria used by Tarlov to distinguish perineural cysts from meningeal diverticula. We present a case of multiple thoracolumbar perineural cysts, one of which was considered the cause of intermittent intercostal neuralgia with atypical findings on postmyelographic computed tomography seen as selective filling of contrast medium. Read More

    Statistical Permutation-based Artery Mapping (SPAM): a novel approach to evaluate imaging signals in the vessel wall.
    BMC Med Imaging 2017 May 26;17(1):36. Epub 2017 May 26.
    European Institute for Molecular Imaging (EIMI), University of Münster, Münster, Germany.
    Background: Cardiovascular diseases are the leading cause of death worldwide. A prominent cause of cardiovascular events is atherosclerosis, a chronic inflammation of the arterial wall that leads to the formation of so called atherosclerotic plaques. There is a strong clinical need to develop new, non-invasive vascular imaging techniques in order to identify high-risk plaques, which might escape detection using conventional methods based on the assessment of the luminal narrowing. Read More

    Importance of correctly interpreting magnetic resonance imaging to diagnose posterior reversible encephalopathy syndrome associated with HELLP syndrome: a case report.
    BMC Med Imaging 2017 May 25;17(1):35. Epub 2017 May 25.
    Obstetrics & Gynecology, Hospital of International University of Health and Welfare, 537-3, Iguchi, Nasushiobara, Tochigi, 329-2763, Japan.
    Background: Severe haemolysis, elevated liver enzyme levels, and low platelet count (HELLP) syndrome in pregnancy are possible underlying trigger factors for posterior reversible encephalopathy syndrome (PRES). Magnetic resonance imaging (MRI) shows diffuse signal abnormalities involving the subcortical white matter in the parieto-occipital lobes. Although the diagnosis of RPES was clearly established by the distinctive reversibility of clinical and radiological abnormalities, it is difficult to distinguish from differential diagnosis. Read More

    Deterministic compressive sampling for high-quality image reconstruction of ultrasound tomography.
    BMC Med Imaging 2017 May 25;17(1):34. Epub 2017 May 25.
    Faculty of Electronics & Telecommunications, VNU University of Engineering & Technology, Hanoi, Vietnam.
    Background: A well-known diagnostic imaging modality, termed ultrasound tomography, was quickly developed for the detection of very small tumors whose sizes are smaller than the wavelength of the incident pressure wave without ionizing radiation, compared to the current gold-standard X-ray mammography. Based on inverse scattering technique, ultrasound tomography uses some material properties such as sound contrast or attenuation to detect small targets. The Distorted Born Iterative Method (DBIM) based on first-order Born approximation is an efficient diffraction tomography approach. Read More

    The effect of initial teaching on evaluation of left ventricular volumes by cardiovascular magnetic resonance imaging: comparison between complete and intermediate beginners and experienced observers.
    BMC Med Imaging 2017 May 17;17(1):33. Epub 2017 May 17.
    Division of Imaging Sciences and Biomedical Engineering, King's College London, London, UK.
    Background: High reproducibility and low intra- and interobserver variability are important strengths of cardiac magnetic resonance (CMR). In clinical practice a significant learning curve may however be observed. Basic CMR courses offer an average of 1. Read More

    Rapid Cartesian versus radial acquisition: comparison of two sequences for hepatobiliary phase MRI at 3 tesla in patients with impaired breath-hold capabilities.
    BMC Med Imaging 2017 May 9;17(1):32. Epub 2017 May 9.
    Department of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
    Background: Hepatocyte-specific gadolinium based contrast agents (HSCA) provide substantial information for the classification of liver lesions in magnetic resonance imaging (MRI). However, breathing artifacts which reduce image quality and diagnostic confidence of hepatobiliary phase acquisitions are regularly observed in clinical routine. The aim of this study was to evaluate two approaches to reduce breathing artifacts for hepatobiliary phase imaging. Read More

    Evaluation of patients with painful total hip arthroplasty using combined single photon emission tomography and conventional computerized tomography (SPECT/CT) - a comparison of semi-quantitative versus 3D volumetric quantitative measurements.
    BMC Med Imaging 2017 May 8;17(1):31. Epub 2017 May 8.
    Department of Orthopaedic Surgery and Traumatology, Kantonsspital Baselland Bruderholz, Liestal, Laufen, Switzerland.
    Background: It was the primary purpose of our study to evaluate the inter- and intra-observer reliability of a standardized SPECT/CT algorithm for evaluating patients with painful primary total hip arthroplasty (THA). The secondary purpose was a comparison of semi-quantitative and 3D volumetric quantification method for assessment of bone tracer uptake (BTU) in those patients.

    Methods: A novel SPECT/CT localization scheme consisting of 14 femoral and 4 acetabular regions on standardized axial and coronal slices was introduced and evaluated in terms of inter- and intra-observer reliability in 37 consecutive patients with hip pain after THA. Read More

    Semi-automated brain tumor segmentation on multi-parametric MRI using regularized non-negative matrix factorization.
    BMC Med Imaging 2017 May 4;17(1):29. Epub 2017 May 4.
    Department of Electrical Engineering (ESAT), STADIUS Centre for Dynamical Systems, Signal Processing and Data Analytics, KULeuven, Kasteelpark Arenberg, Leuven, Belgium.
    Background: Segmentation of gliomas in multi-parametric (MP-)MR images is challenging due to their heterogeneous nature in terms of size, appearance and location. Manual tumor segmentation is a time-consuming task and clinical practice would benefit from (semi-) automated segmentation of the different tumor compartments.

    Methods: We present a semi-automated framework for brain tumor segmentation based on non-negative matrix factorization (NMF) that does not require prior training of the method. Read More

    Registration error of the liver CT using deformable image registration of MIM Maestro and Velocity AI.
    BMC Med Imaging 2017 May 4;17(1):30. Epub 2017 May 4.
    Proton Medical Research Center, University of Tsukuba, 1-1-1, Tennoudai, Tsukuba, Japan.
    Background: Understanding the irradiated area and dose correctly is important for the reirradiation of organs that deform after irradiation, such as the liver. We investigated the spatial registration error using the deformable image registration (DIR) software products MIM Maestro (MIM) and Velocity AI (Velocity).

    Methods: Image registration of pretreatment computed tomography (CT) and posttreatment CT was performed in 24 patients with liver tumors. Read More

    A comparison of pediatric and adult CT organ dose estimation methods.
    BMC Med Imaging 2017 Apr 26;17(1):28. Epub 2017 Apr 26.
    Department of Medical Physics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 84, New York, NY, 10065, USA.
    Background: Computed Tomography (CT) contributes up to 50% of the medical exposure to the United States population. Children are considered to be at higher risk of developing radiation-induced tumors due to the young age of exposure and increased tissue radiosensitivity. Organ dose estimation is essential for pediatric and adult patient cancer risk assessment. Read More

    Semi-automatic synthesis and biodistribution of N-(2-18F-fluoropropionyl)-bis(zinc (II)-dipicolylamine) (18F-FP-DPAZn2) for AD model imaging.
    BMC Med Imaging 2017 Apr 21;17(1):27. Epub 2017 Apr 21.
    Department of Nuclear Medicine, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.
    Background: Phosphatidylserine (PS)-targeting positron emission tomography (PET) imaging with labeled small-molecule tracer is a crucial non-invasive molecule imaging method of apoptosis. In this study, semi-automatic radiosynthesis and biodistribution of N-(2-18F-fluoropropionyl)-bis(zinc(II)-dipicolylamine) (18F-FP-DPAZn2), as a potential small-molecule tracer for PET imaging of cell death in Alzheimer's disease (AD) model, were performed.

    Methods: 18F-FP-DPAZn2 was synthesized on the modified PET-MF-2V-IT-I synthesizer. Read More

    Usefulness of grayscale inverted images in addition to standard images in digital mammography.
    BMC Med Imaging 2017 Apr 18;17(1):26. Epub 2017 Apr 18.
    Department of Statistics, Faculty of Science, Selcuk University, Konya, Turkey.
    Background: Mammography is essential for early diagnosis of breast cancer, which is the most common type of cancer in females that is associated with a high mortality rate. We investigated whether evaluation of the grayscale inverted images of mammograms would aid in increasing the diagnostic sensitivity of the mammographic imaging technique.

    Methods: Our study included 636 mammograms of 159 women who had undergone digital mammography. Read More

    Estimation of myocardial deformation using correlation image velocimetry.
    BMC Med Imaging 2017 Apr 5;17(1):25. Epub 2017 Apr 5.
    Department of Aerospace Engineering, Indian Institute of Technology Madras, Chennai, 600036, India.
    Background: Tagged Magnetic Resonance (tMR) imaging is a powerful technique for determining cardiovascular abnormalities. One of the reasons for tMR not being used in routine clinical practice is the lack of easy-to-use tools for image analysis and strain mapping. In this paper, we introduce a novel interdisciplinary method based on correlation image velocimetry (CIV) to estimate cardiac deformation and strain maps from tMR images. Read More

    Image quality improvement using model-based iterative reconstruction in low dose chest CT for children with necrotizing pneumonia.
    BMC Med Imaging 2017 Mar 16;17(1):24. Epub 2017 Mar 16.
    Imaging Center, Beijing Children's Hospital, Capital Medical University, No.56, Nanlishi Road, Xicheng District, Beijing, 100045, People's Republic of China.
    Background: Model-based iterative reconstruction (MBIR) is a promising reconstruction method which could improve CT image quality with low radiation dose. The purpose of this study was to demonstrate the advantage of using MBIR for noise reduction and image quality improvement in low dose chest CT for children with necrotizing pneumonia, over the adaptive statistical iterative reconstruction (ASIR) and conventional filtered back-projection (FBP) technique.

    Methods: Twenty-six children with necrotizing pneumonia (aged 2 months to 11 years) who underwent standard of care low dose CT scans were included. Read More

    Analysis of the three-dimensional anatomical variance of the distal radius using 3D shape models.
    BMC Med Imaging 2017 Mar 9;17(1):23. Epub 2017 Mar 9.
    Computational Imaging Research Laboratory, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Waehringer Guertel 18-20, Vienna, 1090, Austria.
    Background: Various medical fields rely on detailed anatomical knowledge of the distal radius. Current studies are limited to two-dimensional analysis and biased by varying measurement locations. The aims were to 1) generate 3D shape models of the distal radius and investigate variations in the 3D shape, 2) generate and assess morphometrics in standardized cut planes, and 3) test the model's classification accuracy. Read More

    Focused cardiac ultrasound by unselected residents-the challenges.
    BMC Med Imaging 2017 Mar 4;17(1):22. Epub 2017 Mar 4.
    Department of cardiology, Vestfold Hospital Trust, Po. Box 2168, N3103, Tønsberg, Norway.
    Background: Focus Cardiac Ultrasound (FoCUS) performed by internal medicine residents on call with 2 h of training can provide a means for ruling out cardiac disease, but with poor sensitivity. The purpose of the present study was to evaluate diagnostic usefulness as well as diagnostic accuracy of FoCUS following 4 h of training.

    Methods: All residents on call were given a 4-h training course with an additional one-hour training course after 6 months. Read More

    Ultrasonographic prevalence and characteristics of non-palpable thyroid incidentalomas in a hospital-based population in a sub-Saharan country.
    BMC Med Imaging 2017 Mar 4;17(1):21. Epub 2017 Mar 4.
    Douala General Hospital, Douala, Cameroon.
    Background: Thyroid incidentalomas (TI) are highly prevalent asymptomatic thyroid nodules with ultrasound as the best imaging modality for their detection and characterization. Although they are mostly benign, potential for malignancy is up to 10-15%. In sub-Saharan Africa little data exists on the prevalence and risk categorization of TI. Read More

    Evaluating segmental liver function using T1 mapping on Gd-EOB-DTPA-enhanced MRI with a 3.0 Tesla.
    BMC Med Imaging 2017 Mar 1;17(1):20. Epub 2017 Mar 1.
    Department of Radiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530021, People's Republic of China.
    Background: Assessing the liver function provides valuable information to evaluate surgical risk and plan accordingly. Current studies focus on whole liver function evaluation. However, assessment of segmental liver function is equally important in the clinical practice. Read More

    1 OF 9