7,809 results match your criteria BMC Infectious Diseases[Journal]


Comparison of clinical features of acute lower respiratory tract infections in infants with RSV/HRV infection, and incidences of subsequent wheezing or asthma in childhood.

BMC Infect Dis 2020 May 30;20(1):387. Epub 2020 May 30.

Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, 100045, China.

Background: To compare the clinical characteristics of acute lower respiratory tract infections (ALRTIs) caused by respiratory syncytial virus (RSV) and human rhinovirus (HRV) and to explore the relationship between the development of recurrent wheezing/asthma and RSV/ HRV infections in infancy.

Methods: Retrospective study was conducted to compare the clinical characteristics of acute lower respiratory tract infections (ALRTIs). Hospitalized patients with ALRTIs from March 2007 to December 2016 were screened. Read More

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http://dx.doi.org/10.1186/s12879-020-05094-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260463PMC

Epidemiology and risk factors of Staphylococcus aureus CC398 bone and joint infections.

BMC Infect Dis 2020 May 29;20(1):384. Epub 2020 May 29.

Maladies infectieuses et tropicales, Centre Hospitalier Régional Universitaire, 25030, Besancon, France.

Background: A particular ability of the Staphylococcus aureus clonal complex 398 (CC398) to cause bone and joint infections (BJI) remains questionable, since some studies have described high prevalence of MSSA CC398 in prosthetic joint infection (PJI) and diabetic foot ostemolyelitis (DFO). Here, we described the long-term epidemiology of CC398 among S. aureus isolated from BJI and identified risk factors associated with CC398. Read More

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http://dx.doi.org/10.1186/s12879-020-05098-0DOI Listing

Prognostic accuracy of SIRS criteria and qSOFA score for in-hospital mortality among influenza patients in the emergency department.

BMC Infect Dis 2020 May 29;20(1):385. Epub 2020 May 29.

Department of Emergency Medicine, Linkou Medical Center, Chang-Gung Memorial Hospital, Taoyuan, Taiwan.

Background: The seasonal influenza epidemic is an important public health issue worldwide. Early predictive identification of patients with potentially worse outcome is important in the emergency department (ED). Similarly as with bacterial infection, influenza can cause sepsis. Read More

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http://dx.doi.org/10.1186/s12879-020-05102-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256917PMC

Clients' perceptions of barriers and facilitators to implementing hepatitis C virus care in homeless shelters.

BMC Infect Dis 2020 May 29;20(1):386. Epub 2020 May 29.

Department of Medicine, University of California San Francisco, Zuckerberg San Francisco General, Hospital and Trauma Center, 1001 Potrero Avenue, NH-3D, San Francisco, CA, 94110, USA.

Background: Hepatitis C virus (HCV) is highly prevalent among homeless persons, yet barriers continue to impede HCV testing and treatment in this population. We studied the experiences of homeless individuals related to accessing HCV care to inform the design of a shelter-based HCV prevention and treatment program.

Methods: Homeless shelter clients (10 women and 10 men) of a large shelter in San Francisco participated in gender segregated focus groups. Read More

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http://dx.doi.org/10.1186/s12879-020-05103-6DOI Listing

Human immunodeficiency virus positive status disclosure to a sexual partner and its determinant factors in Ethiopia: a systematic review and meta-analysis.

BMC Infect Dis 2020 May 29;20(1):382. Epub 2020 May 29.

Rift Valley University, Addis Ababa, Ethiopia.

Background: Disclosure of Human Immunodeficiency Virus positive status significantly reduced the transmission of HIV; yet, it remains a challenge for many HIV patients. Disclosure serves plays a crucial role to raise awareness and to reduce risky behaviors. Hence, this study aimed to determine the pooled prevalence and effect sizes of determinant factors of HIV positive status disclosure through a systematic review and meta-analysis of the results of the existing primary studies in Ethiopia. Read More

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http://dx.doi.org/10.1186/s12879-020-05081-9DOI Listing

Neurocognitive impairment in treatment-experienced adults living with HIV attending primary care clinics in Zimbabwe.

BMC Infect Dis 2020 May 29;20(1):383. Epub 2020 May 29.

Department of Psychiatry, College of Health Sciences, African Mental Health Research Initiative, University of Zimbabwe, Harare, Zimbabwe.

Background: HIV affects the central nervous system resulting in HIV associated neurocognitive impairment (NCI) in approximately 50% of people living with HIV. It typically affects memory, learning, working memory, fine motor skills, speed of information processing, verbal fluency and executive functioning cognitive domains. NCI can affect adherence to antiretroviral therapy (ART), employability, driving ability and activities of daily living. Read More

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http://dx.doi.org/10.1186/s12879-020-05090-8DOI Listing

Cryptococcus meningitis mimicking cerebral septic emboli, a case report series demonstrating injection drug use as a risk factor for development of disseminated disease.

BMC Infect Dis 2020 May 27;20(1):381. Epub 2020 May 27.

Atrium Health Department of Medicine, Charlotte, NC, USA.

Background: Clinicians may be less inclined to consider a diagnosis of cryptococcal meningitis in people without HIV infection or transplant-related immunosuppression. This may lead to a delay in diagnosis particularly if disseminated cryptococcal disease mimics cerebral septic emboli in injection drug use (IDU) leading to a search for endocarditis or other infectious sources. Though, IDU has been described as a potential risk for disseminated cryptococcal disease. Read More

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http://dx.doi.org/10.1186/s12879-020-05108-1DOI Listing

Intestinal parasitosis, anaemia and risk factors among pre-school children in Tigray region, northern Ethiopia.

BMC Infect Dis 2020 May 27;20(1):379. Epub 2020 May 27.

Department of Medical Microbiology, College of Health Sciences, Aksum University, Tigray, Ethiopia.

Background: Intestinal parasitic infections (IPIs) and anaemia are major health problems. This study assessed the prevalence of intestinal parasitic infections, anaemia and associated factors among pre-school children in rural areas of the Tigray region, northern Ethiopia.

Methods: A community based cross-sectional study was conducted among 610 pre-school children in rural communities of Northern Ethiopia from June 2017 to August 2017. Read More

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http://dx.doi.org/10.1186/s12879-020-05101-8DOI Listing

Prevalence and associated factors of scabies in Ethiopia: systematic review and Meta-analysis.

BMC Infect Dis 2020 May 27;20(1):380. Epub 2020 May 27.

Department of Epidemiology and Biostatistics, School of Public health, College of Medicine and Health Science, Bahir Dar University, Bahir Dar, Ethiopia.

Background: Scabies is an infectious disease that affects the skin caused by the mite Sarcoptes scabiei and it transmitted through close personal contact. Even though it is easily treatable disease, its prevalence is high and continuous as neglected tropical disease of resource-poor settings, and particularly affects young age groups. Despite of these facts, studies conducted in Ethiopia regarding to the prevalence and associated factors for scabies infestation have been highly variable and didn't well compiled. Read More

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http://dx.doi.org/10.1186/s12879-020-05106-3DOI Listing

Case report: nosocomial fungemia caused by Candida diddensiae.

BMC Infect Dis 2020 May 27;20(1):377. Epub 2020 May 27.

Department of Laboratory Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea.

Background: Candida diddensiae, a yeast found in olive oil, is considered non-pathogenic to humans. Here, we describe the first case of fungemia caused by C. diddensiae in a hospitalized patient with underlying diseases. Read More

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http://dx.doi.org/10.1186/s12879-020-05095-3DOI Listing

A rare case of brain abscess caused by Actinomyces meyeri.

BMC Infect Dis 2020 May 27;20(1):378. Epub 2020 May 27.

Division of Infectious Disease, East Carolina University Brody School of Medicine, Greenville, NC, USA.

Background: Brain abscesses are the rare and most severe form of actinomycosis, which usually manifests as abscesses of the occipital or parietal lobe due to direct expansion from an adjacent area, the oral cavity. In the medical literature, there are only a few reported cases of brain abscess caused by Actinomyces meyeri. In this report, we present a 35-year-old male patient who experienced an insidious headache and left-sided weakness and was diagnosed with an Actinomyces meyeri brain abscess. Read More

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http://dx.doi.org/10.1186/s12879-020-05100-9DOI Listing

Molecular epidemiology and socio-demographic risk factors of sexually transmitted infections among women in Lebanon.

BMC Infect Dis 2020 May 27;20(1):375. Epub 2020 May 27.

Faculty of Health Sciences, University of Balamand, P.O.Box 166378 Ashrafieh, Beirut, 1100-2807, Lebanon.

Background: Sexually transmitted infections (STIs) cause a major public health problem that affect both men and women in developing and developed countries. The aim of the study was to estimate the prevalence of 11 STIs among women who voluntarily participated in the study, while seeking gynecological checkup. The existence of an association between the presence of pathogens and symptoms and various sociodemographic risk factors was assessed. Read More

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http://dx.doi.org/10.1186/s12879-020-05066-8DOI Listing

Efficacy of a single dose versus a multiple dose regimen of Mebendazole against hookworm infections among school children: a randomized open-label trial.

BMC Infect Dis 2020 May 27;20(1):376. Epub 2020 May 27.

Department of Medical Parasitology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, P.O.Box: 196, Gondar, Ethiopia.

Background: Despite the existence of a population-based control program using single dose albendazole or mebendazole as a preventive chemotherapy, hookworm transmission remains high. It causes a negative impact on the growth and school performance of children. In connection to this preventive chemotherapy, different studies produced conflicting results. Read More

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http://dx.doi.org/10.1186/s12879-020-05097-1DOI Listing

The effect of oral care intervention on pneumonia hospitalization, Staphylococcus aureus distribution, and salivary bacterial concentration in Taiwan nursing home residents: a pilot study.

BMC Infect Dis 2020 May 27;20(1):374. Epub 2020 May 27.

School of Dentistry, College of Dental Medicine, Kaohsiung Medical University, No.100, Shiquan 1st Rd., Sanmin Dist., Kaohsiung City, 807, Taiwan.

Background: Elevated Staphylococcus aureus and oral bacterial concentrations are known to correlate with pneumonia hospitalization in nursing home residents. However, the effects of a professional oral care intervention on these factors remain unclear. The aims of this quasi-experimental study were to compare bacterial concentrations in saliva and sputum, oral health status, distribution of Staphylococcus aureus, and pneumonia status before and after a professional oral care intervention. Read More

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http://dx.doi.org/10.1186/s12879-020-05061-zDOI Listing

Resurgence risk for malaria, and the characterization of a recent outbreak in an Amazonian border area between French Guiana and Brazil.

BMC Infect Dis 2020 May 26;20(1):373. Epub 2020 May 26.

ESPACE-DEV, IRD, Universités de Montpellier, de La Réunion, de la Guyane, des Antilles, Montpellier, France: LIS, ICICT, Fiocruz, Av. Brasil, 4365, Manguinhos, Rio de Janeiro, Brazil.

Background: In 2017, inhabitants along the border between French Guiana and Brazil were affected by a malaria outbreak primarily due to Plasmodium vivax (Pv). While malaria cases have steadily declined between 2005 and 2016 in this Amazonian region, a resurgence was observed in 2017.

Methods: Two investigations were performed according to different spatial scales and information details: (1) a local study on the French Guiana border, which enabled a thorough investigation of malaria cases treated at a local village health center and the entomological circumstances in the most affected neighborhood, and (2) a regional and cross-border study, which enabled exploration of the regional spatiotemporal epidemic dynamic. Read More

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http://dx.doi.org/10.1186/s12879-020-05086-4DOI Listing

Diagnostic performance of APRI and FIB-4 for confirming cirrhosis in Indonesian HIV/HCV co-infected patients.

BMC Infect Dis 2020 May 25;20(1):372. Epub 2020 May 25.

Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Diponegoro, Jakarta, 71, Indonesia.

Background: After successful of antiretroviral therapy, highly effective direct acting antiviral (DAA) make HCV elimination reasonable in HIV/HCV co-infected patients. However, in achieving this target, there are still barriers to start DAA treatment, particularly in the area of liver fibrosis assessment that determine the duration of therapy. We aimed to assess the diagnostic performance of APRI and FIB-4 for diagnosing cirrhosis in HIV/HCV co-infected patients using hepatic transient elastography (TE) as gold standard. Read More

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http://dx.doi.org/10.1186/s12879-020-05069-5DOI Listing

Prevalence and risk factors related to poor outcome of patients with severe Plasmodium vivax infection: a systematic review, meta-analysis, and analysis of case reports.

BMC Infect Dis 2020 May 24;20(1):363. Epub 2020 May 24.

Department of Medical Technology, Far Eastern University, Manila, Philippines.

Background: Plasmodium vivax rarely develops severe complications when compared to severe falciparum malaria. However, severe vivax malaria also needs urgent, intensive care and treatment as severe falciparum malaria. This systematic review aimed to explore pooled prevalence of severe vivax malaria and to identify factors related to poor outcome of patients who developed severe manifestation. Read More

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http://dx.doi.org/10.1186/s12879-020-05046-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245863PMC

Identification of Kosakonia cowanii as a rare cause of acute cholecystitis: case report and review of the literature.

BMC Infect Dis 2020 May 24;20(1):366. Epub 2020 May 24.

Institute for Medical Microbiology, Virology and Hygiene, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.

Background: Kosakonia cowanii, formerly known as Enterobacter cowanii, is a Gram-negative bacillus belonging to the order Enterobacterales. The species is usually recognized as a plant pathogen and has only anecdotally been encountered as a human pathogen. Here we describe the rare case of a K. Read More

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http://dx.doi.org/10.1186/s12879-020-05084-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245821PMC

Successful bedaquiline-containing antimycobacterial treatment in post-traumatic skin and soft-tissue infection by Mycobacterium fortuitum complex: a case report.

BMC Infect Dis 2020 May 24;20(1):365. Epub 2020 May 24.

Technical University of Munich, School of Medicine, University Hospital Rechts der Isar, Department of Internal Medicine II, Ismaningerstrasse 22, 81675, Munich, Germany.

Background: Mycobacterium fortuitum complex is a group of rapidly growing nontuberculous mycobacteria (NTM) associated with skin and soft-tissue infections after surgery or trauma. Treatment of NTM is challenging, due to resistance to multiple antimycobacterial agents. Bedaquiline is a diarylquinoline that inhibits mycobacterial ATP-synthase. Read More

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http://dx.doi.org/10.1186/s12879-020-05075-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245858PMC

Early diagnosis and appropriate respiratory support for Mycoplasma pneumoniae pneumonia associated acute respiratory distress syndrome in young and adult patients: a case series from two centers.

BMC Infect Dis 2020 May 24;20(1):367. Epub 2020 May 24.

Department of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine, Beijing Key Laboratory of Respiratory and Pulmonary Circulation, Beijing Chao-Yang Hospital, Capital Medical University, No. 8 Gongren Tiyuchang Nanlu, Chaoyang District, Beijing, 100020, China.

Background: Mycoplasma pneumoniae (M. pneumoniae) is one of the most common causes of community acquired pneumonia (CAP). Establishing an early diagnosis of M. Read More

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http://dx.doi.org/10.1186/s12879-020-05085-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245847PMC

Underdiagnoses of Rickettsia in patients hospitalized with acute fever in Indonesia: observational study results.

BMC Infect Dis 2020 May 24;20(1):364. Epub 2020 May 24.

Hasan Sadikin Hospital - Faculty of Medicine Universitas Padjadjaran, Bandung, Indonesia.

Background: Reports of human rickettsial infection in Indonesia are limited. This study sought to characterize the epidemiology of human rickettsioses amongst patients hospitalized with fever at 8 tertiary hospitals in Indonesia.

Methods: Acute and convalescent blood from 975 hospitalized non-dengue patients was tested for Rickettsia IgM and IgG by ELISA. Read More

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http://dx.doi.org/10.1186/s12879-020-05057-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245627PMC

Live poultry market closure and avian influenza A (H7N9) infection in cities of China, 2013-2017: an ecological study.

BMC Infect Dis 2020 May 24;20(1):369. Epub 2020 May 24.

School of Public Health, Key Laboratory of Tropical Diseases Control of Ministry of Education, One Health Center of Excellence for Research &Training, Sun Yat-sen University, Guangzhou, China.

Background: Previous studies have proven that the closure of live poultry markets (LPMs) was an effective intervention to reduce human risk of avian influenza A (H7N9) infection, but evidence is limited on the impact of scale and duration of LPMs closure on the transmission of H7N9.

Method: Five cities (i.e. Read More

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http://dx.doi.org/10.1186/s12879-020-05091-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245998PMC

Hepatitis E virus infection in pregnant women, Argentina.

BMC Infect Dis 2020 May 24;20(1):368. Epub 2020 May 24.

Instituto de Virología "Dr. J. M. Vanella", Facultad de Ciencias Médicas, Universidad Nacional de Córdoba (UNC), Enfermera Gordillo Gómez, s/n (without number), X5016, Córdoba, Argentina.

Background: Hepatitis E virus (HEV) infection is an important cause of acute hepatitis worldwide. In pregnant women, HEV can cause more severe symptoms, with high rates of fatal hepatic failure in endemic countries. However, HEV prevalence and circulation among pregnant women from South America is almost unknown. Read More

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http://dx.doi.org/10.1186/s12879-020-05087-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245834PMC

Precision diagnosis and therapy of a case of brain abscesses associated with asymptomatic pulmonary arteriovenous fistulas.

BMC Infect Dis 2020 May 24;20(1):370. Epub 2020 May 24.

Department of Neurology, Qilu Hospital of Shandong University, Jinan, 250012, Shandong Province, China.

Background: Brain abscesses, a severe infectious disease of the CNS, are usually caused by a variety of different pathogens, which include Streptococcus intermedius (S. intermedius). Pulmonary arteriovenous fistulas (PAVFs), characterized by abnormal direct communication between pulmonary artery and vein, are a rare underlying cause of brain abscesses. Read More

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http://dx.doi.org/10.1186/s12879-020-05092-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247166PMC

A retrospective study on Xpert MTB/RIF for detection of tuberculosis in a teaching hospital in China.

BMC Infect Dis 2020 May 24;20(1):362. Epub 2020 May 24.

Department of Clinical Laboratory, Peking University People's Hospital, Xizhimen South Avenue No.11, Beijing, 100044, China.

Background: The Xpert MTB/RIF assay is an automated molecular test that is designed to simultaneously detect Mycobacterium tuberculosis (MTB) complex and rifampin resistance. However, there are relatively few studies on this method in China. Xpert has been routinely used at Peking University People's Hospital (PKUPH) since November 2016. Read More

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http://dx.doi.org/10.1186/s12879-020-05004-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245878PMC

Zika virus in southeastern Senegal: survival of the vectors and the virus during the dry season.

BMC Infect Dis 2020 May 24;20(1):371. Epub 2020 May 24.

Pôle de Zoologie Médicale, Institut Pasteur de Dakar, 36 Avenue Pasteur, BP 220, Dakar, Senegal.

Background: Zika virus (ZIKV, genus Flavivirus, family Flaviviridae) is transmitted mainly by Aedes mosquitoes. This virus has become an emerging concern of global public health with recent epidemics associated to neurological complications in the pacific and America. ZIKV is the most frequently amplified arbovirus in southeastern Senegal. Read More

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http://dx.doi.org/10.1186/s12879-020-05093-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247193PMC

Carriage rate of Neisseria meningitidis, antibiotic susceptibility pattern and associated risk factors among primary school children in Gondar town, Northwest Ethiopia.

BMC Infect Dis 2020 May 20;20(1):358. Epub 2020 May 20.

Department of Medical Microbiology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Background: Globally, in 2012, about 1.2 million estimated cases were reported with ~ 135,000 deaths annually. In Ethiopia, specifically in our study area, limited information is found on the oropharyngeal carriage, antimicrobial resistance pattern, and associated risk factors for N. Read More

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http://dx.doi.org/10.1186/s12879-020-05080-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238561PMC

A case of acanthosis nigricans in a HIV-infected patient.

BMC Infect Dis 2020 May 20;20(1):360. Epub 2020 May 20.

Department of Public Health and Infectious Diseases, "Sapienza" University of Rome, Rome, Italy.

Background: To date, very little information is available concerning the relationship between acanthosis nigricans (AN) and infection with human immunodeficiency virus type 1 (HIV-1).

Case Presentation: Herein, we report the case of a middle-aged man admitted for fever and progressively worsening dyspnea in the context of an opportunistic pneumonia and firstly diagnosed with acquired immunodeficiency syndrome (AIDS). At the time of diagnosis, physical examination revealed the presence of a palpable, hyperpigmented skin lesion on the left areola with surface desquamation and velvety texture consistent with AN. Read More

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http://dx.doi.org/10.1186/s12879-020-05089-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238735PMC

Adherence to guidelines across different specialties to prevent infections in patients undergoing immunosuppressive therapies.

BMC Infect Dis 2020 May 20;20(1):359. Epub 2020 May 20.

Department of Haematology, James Cook University Hospital, Middlesbrough, UK.

Background: Substantial numbers of patients are now receiving either immunosuppressive therapies or chemotherapy. There are significant risks in such patients of developing opportunistic infections or re-activation of latent infections, with higher associated morbidity and mortality. The aim of this quality improvement project was to determine how effective 5 different specialties were in assessing and mitigating risks of developing opportunistic infections or re-activation of latent infections in patients undergoing immunosuppressive therapies. Read More

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http://dx.doi.org/10.1186/s12879-020-05082-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238578PMC

Meningococcaemia causing necrotizing cellulitis associated with acquired complement deficiency after gastric bypass surgery: a case report.

BMC Infect Dis 2020 May 20;20(1):361. Epub 2020 May 20.

Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles, 808 Route de Lennik, Brussels, Belgium.

Background: Neisseria meningitidis has rarely been described as an agent of necrotic soft tissue infection.

Case Presentation: We report a case of a septic shock with necrotizing cellulitis due to Neisseria meningitidis serogroup W, treated by urgent extensive surgical debridement followed by skin grafts. The invasive meningococcal disease occurred together with a complement deficiency, possibly acquired after bypass surgery that took place 1 year before. Read More

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http://dx.doi.org/10.1186/s12879-020-05079-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240913PMC

Unusual subdural empyema in a homeless patient diagnosed by molecular approach: a case report.

BMC Infect Dis 2020 May 19;20(1):357. Epub 2020 May 19.

Sorbonne Université, Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pierre-Louis d'Epidémiologie et de Santé Publique, Paris, France.

Background: We report a case of subdural empyema in a homeless patient caused by Bartonella quintana. B. quintana is a facultative intracellular bacteria for which bacterial growth is fastidious. Read More

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http://dx.doi.org/10.1186/s12879-020-05088-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236200PMC

Performance of malaria microscopy external quality assessment and networking among health facilities in west Amhara region, Ethiopia.

BMC Infect Dis 2020 May 19;20(1):355. Epub 2020 May 19.

Amhara Public Health Institute, P.O. BOX: 477, Bahir Dar, Ethiopia.

Background: Microscopic examination of peripheral blood smear produces reliable results both about the malaria infection status and level of parasitemia. However, test results are affected by skill of the laboratory personnel, workload, condition of microscopes and quality of laboratory supplies. Therefore, continuous monitoring of the performance of laboratories is of pivotal importance in order to make timely correction. Read More

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http://dx.doi.org/10.1186/s12879-020-05077-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236141PMC
May 2020
2.613 Impact Factor

Pathogen analysis of pertussis-like syndrome in children.

BMC Infect Dis 2020 May 19;20(1):353. Epub 2020 May 19.

Department of Respiration, Children's Hospital of Soochow University, No. 303 Jing De Road, Suzhou, 215003, China.

Background: The aim of the study was to identify the pathogens, in addition to bordetella pertussis (B. pertussis), which cause pertussis-like syndrome in children and to compare clinical presentation between those with B. pertussis and pertussis-like syndrome. Read More

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http://dx.doi.org/10.1186/s12879-020-05074-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236299PMC

Spontaneous community-acquired PVL-producing Staphylococcus aureus mediastinitis in an immunocompetent adult - a case report.

BMC Infect Dis 2020 May 19;20(1):354. Epub 2020 May 19.

Réanimation polyvalente, CHU Dupuytren, 2 avenue Martin Luther King, F-87000, Limoges, France.

Background: Mediastinitis caused by hematogenous spread of an infection is rare. We report the first known case of community-acquired mediastinitis from hematogenous origin in an immunocompetent adult. This rare invasive infection was due to Panton-Valentine Leucocidin-producing (PVL+) methicillin-susceptible Staphylococcus aureus (MSSA). Read More

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http://dx.doi.org/10.1186/s12879-020-05076-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236110PMC

Solutions to improve the latent tuberculosis Cascade of Care in Ghana: a longitudinal impact assessment.

BMC Infect Dis 2020 May 18;20(1):352. Epub 2020 May 18.

McGill International TB Centre, Montreal, QC, Canada.

Background: Loss of patients in the latent tuberculosis infection (LTBI) cascade of care is a major barrier to LTBI management. We evaluated the impact and acceptability of local solutions implemented to strengthen LTBI management of household contacts (HHCs) at an outpatient clinic in Ghana.

Methods: Local solutions to improve LTBI management were informed by a baseline evaluation of the LTBI cascade and questionnaires administered to index patients, HHCs, and health care workers at the study site in Offinso, Ghana. Read More

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http://dx.doi.org/10.1186/s12879-020-05060-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236456PMC

Lung abscess secondary to lung cancer with Eikenella corrodens and Streptococcus anginosus: a case report.

BMC Infect Dis 2020 May 18;20(1):351. Epub 2020 May 18.

Oncology Center, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.

Background: Eikenella corrodens and Streptococcus anginosus, which are primary colonization bacteria of the normal flora of the oropharynx, are infrequent bacteria, especially the former. Here, we report a case of lung abscess with a coinfection of Eikenella corrodens and Streptococcus anginosus in a lung cancer patient.

Case Presentation: A 66-year-old Chinese man with lung cancer was admitted to the hospital, complaining of a cough and expectoration for five months and fever for two months. Read More

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http://dx.doi.org/10.1186/s12879-020-05054-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236361PMC

Epidemiological analysis of the Kaohsiung city strategy for dengue fever quarantine and epidemic prevention.

BMC Infect Dis 2020 May 15;20(1):347. Epub 2020 May 15.

National Mosquito-Borne Diseases Control Research Center, National Health Research Institutes, Zhunan, Taiwan.

Background: Dengue is endemic in over 100 countries and is an important public health problem worldwide. Dengue fever is not endemic in Taiwan; the importation of dengue viruses from neighboring countries via close commercial links and air travel is considered to be the cause of local outbreaks. Therefore, efforts toward disease control have focused on preventing the importation of dengue into Taiwan. Read More

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http://dx.doi.org/10.1186/s12879-020-4942-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226716PMC
May 2020
2.613 Impact Factor

Ultrasound in managing extrapulmonary tuberculosis: a randomized controlled two-center study.

BMC Infect Dis 2020 May 15;20(1):349. Epub 2020 May 15.

Ifakara Health Institute, Ifakara, United Republic of Tanzania, Off Mlabani Passage, P. O Box 53, Ifakara, Tanzania.

Background: Patients with clinically suspected tuberculosis are often treated empirically, as diagnosis - especially of extrapulmonary tuberculosis - remains challenging. This leads to an overtreatment of tuberculosis and to underdiagnosis of possible differential diagnoses.

Methods: This open-label, parallel-group, superiority randomized controlled trial is done in a rural and an urban center in Tanzania. Read More

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http://dx.doi.org/10.1186/s12879-020-05073-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226714PMC

Molecular prevalence of intestinal parasites infections in children with diarrhea in Franceville, Southeast of Gabon.

BMC Infect Dis 2020 May 15;20(1):350. Epub 2020 May 15.

Unité d'Evolution, Epidémiologie et Résistance Parasitaire (UNEEREP), Centre International de Recherches Médicales de Franceville (CIRMF), BP 769, Franceville, Gabon.

Background: Pediatric diarrhea caused by a range of pathogens, including intestinal parasites, is one of main causes of death among children under 5 years of age. The distribution of these parasitic infections overlaps in many environmental, socioeconomic and epidemiological settings. Their distribution and prevalence varies from region to region. Read More

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http://dx.doi.org/10.1186/s12879-020-05071-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226932PMC

Blackfly fever and dermatitis caused by Simulium kiritshenkoi: a human case report in Iran.

BMC Infect Dis 2020 May 15;20(1):348. Epub 2020 May 15.

Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Background: Besides the considerable role of blackflies to the transmission of many disease agents, these flies considered as annoying biting pests of wildlife, livestock, poultry, and humans. There are few literature reports of blackfly fever following Simulium spp. This study describes a case of blackfly fever and dermatitis following blackflies numerous bites in Iran. Read More

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http://dx.doi.org/10.1186/s12879-020-05070-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227273PMC

Prevalence of sexually transmitted infections among foreigners living in Guangzhou, China: a cross-sectional study (2010-2017).

BMC Infect Dis 2020 May 14;20(1):345. Epub 2020 May 14.

Department of Microbiology, School of Public Health, Southern Medical University, Guangzhou, 510515, China.

Background: The prevalence of HIV/HCV/HBV/ Treponema pallidum is an essential health issue in China. However, there are few studies focused on foreigners living in China. This study aimed to assess the prevalence and socio-demographic distribution of HIV, HBV, HCV, and T. Read More

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http://dx.doi.org/10.1186/s12879-020-04995-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222532PMC

Epidemiological and genetic investigation of a cluster of cases of severe fever with thrombocytopenia syndrome bunyavirus.

BMC Infect Dis 2020 May 14;20(1):346. Epub 2020 May 14.

Liaoning Province Center for Disease Control and Prevention, Shenyang, Liaoning Province, China.

Background: To analyze and discuss the transmission route of a cluster of cases of severe fever with thrombocytopenia syndrome bunyavirus (SFTSV).

Method: We performed an epidemiological investigation and a genetic analysis of patients with severe fever with thrombocytopenia syndrome (SFTS) caused by SFTSV, their close contacts and the surrounding population.

Results: We found that all patients had contact with the blood of the first patient. Read More

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http://dx.doi.org/10.1186/s12879-020-05072-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227288PMC

Subacute pericardial abscess after aortic valve replacement: a case report.

BMC Infect Dis 2020 May 13;20(1):342. Epub 2020 May 13.

Department of Experimental, Diagnostic and Specialty Medicine-DIMES (Padiglione 23), University of Bologna, Via Giuseppe Massarenti 9, 40138, Bologna, Italy.

Background: Purulent pericarditis is an infectious disease, frequently caused by gram-positive bacteria, that is rarely observed in healthy individuals, and is often associated with predisposing conditions.

Case Presentation: Here, we present the case of an Escherichia coli post-surgical localized purulent pericarditis complicated by transient constrictive pericarditis and its diagnostic and therapeutic management.

Conclusions: Our case report focuses on the importance of imaging-guided treatment of purulent pericardial diseases, in particular on the emerging role of 18 F-labelled 2-fluoro-2-deoxy-D-glucose Positron Emission Tomography/Computed Tomography in pericardial diseases and on the management of transient constrictive pericarditis, often seen after thoracic surgery. Read More

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http://dx.doi.org/10.1186/s12879-020-05063-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218556PMC

Molecular epidemiology of drug resistant Mycobacterium tuberculosis in Africa: a systematic review.

BMC Infect Dis 2020 May 13;20(1):344. Epub 2020 May 13.

DST/NRF Centre of Excellence for Biomedical Tuberculosis Research/South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

Background: The burden of drug resistant tuberculosis in Africa is largely driven by the emergence and spread of multidrug resistant (MDR) and extensively drug resistant (XDR) Mycobacterium tuberculosis strains. MDR-TB is defined as resistance to isoniazid and rifampicin, while XDR-TB is defined as MDR-TB with added resistance to any of the second line injectable drugs and any fluoroquinolone. The highest burden of drug resistant TB is seen in countries further experiencing an HIV epidemic. Read More

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http://dx.doi.org/10.1186/s12879-020-05031-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222473PMC

Molecular characteristics of Clostridium difficile in children with acute gastroenteritis from Zhejiang.

BMC Infect Dis 2020 May 13;20(1):343. Epub 2020 May 13.

School of Laboratory Medicine, Hangzhou Medical College, No. 481, Binwen Road, Hangzhou, Zhejiang, China.

Background: Clostridium difficile infection (CDI) has an increasing pediatric prevalence worldwide. However, molecular characteristics of C. difficile in Chinese children with acute gastroenteritis have not been reported. Read More

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http://dx.doi.org/10.1186/s12879-020-05030-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222317PMC

The effect of body mass index and creatinine clearance on serum trough concentration of vancomycin in adult patients.

BMC Infect Dis 2020 May 13;20(1):341. Epub 2020 May 13.

Department of Pharmacy, Children's Hospital of Soochow University, Suzhou, 215000, China.

Background: The aim of this study was to evaluate the influence of patient body mass index (BMI) and estimated creatinine clearance (CrCl) on serum vancomycin concentrations to define a possible optimal dosage regimen in overweight patients based on data obtained during therapeutic drug monitoring.

Methods: This retrospective study used data collected from January 2017 to January 2019. Adult patients (n = 204) received vancomycin treatment at a dose of 1000 mg every 12 h and underwent serum monitoring. Read More

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http://dx.doi.org/10.1186/s12879-020-05067-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218520PMC
May 2020
2.613 Impact Factor

Antibiotic prescribing among patients with severe infectious diseases in two private sector hospitals in Central India - a time series analysis over 10 years.

BMC Infect Dis 2020 May 13;20(1):340. Epub 2020 May 13.

Department of Global Public Health, Health Systems and Policy. Karolinska Institutet, SE-171 77, Stockholm, Sweden.

Background: Antibiotic resistance is an emerging problem caused due to antibiotic use. In countries with high rates of infectious diseases, antibiotic resistance is a frequent cause of mortality. The aim was to analyse antibiotic prescribing practices between 2008 and 2017 in a teaching (TH) and a non-teaching (NTH) hospital, as typical hospitals of low- and middle-income countries, and to compare antibiotic prescribing for severe infectious indications for which empiric antibiotic treatment is recommended. Read More

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http://dx.doi.org/10.1186/s12879-020-05059-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218632PMC

An unusual case of dengue shock syndrome complicated by ilio-femoral deep vein thrombosis; a case report.

BMC Infect Dis 2020 May 12;20(1):335. Epub 2020 May 12.

Physician, National Hospital of Sri Lanka, Colombo, Sri Lanka.

Background: Dengue fever is a hemorrhagic fever caused by flaviviruses. Hemorrhagic manifestations are well known to be associated with dengue fever, though the thrombotic events are only seldom reported. Underlying pathophysiology of thrombotic events is multifactorial and the management is challenging due to associated thrombocytopenia and bleeding tendency. Read More

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http://dx.doi.org/10.1186/s12879-020-05062-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216574PMC

Peer education for HIV prevention among high-risk groups: a systematic review and meta-analysis.

BMC Infect Dis 2020 May 12;20(1):338. Epub 2020 May 12.

Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, 510080, Guangdong Province, China.

Background: Peer education has become a strategy for health promotion among high-risk groups for HIV infection worldwide. However, the extent to which peer education could have an impact on HIV prevention or the long-term effect of this impact is still unknown. This study thus quantifies the impact of peer education over time among high-risk HIV groups globally. Read More

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http://dx.doi.org/10.1186/s12879-020-05003-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218508PMC