Search our Database of Scientific Publications and Authors

I’m looking for a

    5703 results match your criteria BMC Infectious Diseases[Journal]

    1 OF 115

    Efficacy of a bivalent killed whole-cell cholera vaccine over five years: a re-analysis of a cluster-randomized trial.
    BMC Infect Dis 2018 Feb 20;18(1):84. Epub 2018 Feb 20.
    Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N., Seattle, 98109, WA, USA.
    Background: Oral cholera vaccine (OCV) is a feasible tool to prevent or mitigate cholera outbreaks. A better understanding of the vaccine's efficacy among different age groups and how rapidly its protection wanes could help guide vaccination policy.

    Methods: To estimate the level and duration of OCV efficacy, we re-analyzed data from a previously published cluster-randomized, double-blind, placebo controlled trial with five years of follow-up. Read More

    Factors affecting first month adherence due to antiretroviral therapy among HIV-positive adults at Felege Hiwot Teaching and Specialized Hospital, north-western Ethiopia; a prospective study.
    BMC Infect Dis 2018 Feb 20;18(1):83. Epub 2018 Feb 20.
    School of Mathematics, Statistics and Computer Science, University of Kwazulu Natal, Durban, South Africa.
    Background: Non-adherence to Highly Active Antiretroviral Therapy (HAART) is one of the factors for treatment failure in human immunodeficiency virus (HIV) infected patients in developing countries. The main objective of this study was to identify factors for treatment failure among adult HIV patients based on the assessment of first month adherence in the study area.

    Methods: The study was conducted using secondary data from antiretroviral unit at Felege Hiwot Teaching and Specialized Hospital. Read More

    Using eHealth to engage and retain priority populations in the HIV treatment and care cascade in the Asia-Pacific region: a systematic review of literature.
    BMC Infect Dis 2018 Feb 17;18(1):82. Epub 2018 Feb 17.
    Research Center for Public Health, Tsinghua University, Beijing, 100084, China.
    Background: The exponential growth in the reach and development of new technologies over the past decade means that mobile technologies and social media play an increasingly important role in service delivery models to maximise HIV testing and access to treatment and care. This systematic review examines the impact of electronic and mobile technologies in medical care (eHealth) in the linkage to and retention of priority populations in the HIV treatment and care cascade, focussing on the Asia-Pacific region.

    Methods: The review was informed by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement from the Cochrane Collaboration guidelines. Read More

    IL-10NK and TGF-βNK cells play negative regulatory roles in HIV infection.
    BMC Infect Dis 2018 02 13;18(1):80. Epub 2018 Feb 13.
    Key Laboratory of AIDS Immunology of National Health and Family Planning Commission, Department of Laboratory Medicine, The First Affiliated Hospital, China Medical University, No. 155, Nanjingbei Street, Heping District, Shenyang, Liaoning Province, 110001, China.
    Background: Natural killer (NK) cells play cytotoxic roles by targeting tumor cells or virus infected cells, they also play regulatory roles by secreting cytokines and chemokines. Transforming growth factor (TGF)-β and interleukin (IL)-10 are important immunosuppressive cytokines potentially related to the immune dysregulation that occurs in the infection of human immunodeficiency virus (HIV). NK cells are an important source of TGF-β and a main early producer of IL-10 in response to viral infection. Read More

    Prospective study on human fecal carriage of Enterobacteriaceae possessing mcr-1 and mcr-2 genes in a regional hospital in Hong Kong.
    BMC Infect Dis 2018 02 13;18(1):81. Epub 2018 Feb 13.
    Department of Pathology, 1/F, Li Shu Fan Block, Hong Kong Sanatorium & Hospital, 2 Village Road, Happy Valley, Hong Kong.
    Background: Human fecal carriage of Enterobacteriaceae possessing mobilized colistin resistance genes (mcr-1 and mcr-2) remains obscure in Hong Kong. As part of routine surveillance on emerging antibiotic resistance, we conducted a prospective study on this topic in a regional hospital in Hong Kong.

    Methods: From October 31 to November 25, 2016, all fecal specimens submitted for routine analysis were included in this surveillance study. Read More

    Mortality estimates among adult patients with severe acute respiratory infections from two sentinel hospitals in southern Arizona, United States, 2010-2014.
    BMC Infect Dis 2018 02 12;18(1):78. Epub 2018 Feb 12.
    Arizona Department of Health Services, Border Infectious Disease Surveillance Program, 400 West Congress, Suite 116, Tucson, AZ, 85701, USA.
    Background: From October 2010 through February 2016, Arizona conducted surveillance for severe acute respiratory infections (SARI) among adults hospitalized in the Arizona-Mexico border region. There are few accurate mortality estimates in SARI patients, particularly in adults ≥ 65 years old. The purpose of this study was to generate mortality estimates among SARI patients that include deaths occurring shortly after hospital discharge and identify risk factors for mortality. Read More

    Hepatitis B/C in the countries of the EU/EEA: a systematic review of the prevalence among at-risk groups.
    BMC Infect Dis 2018 02 12;18(1):79. Epub 2018 Feb 12.
    Division of Infectious Disease Control, Municipal Public Health Service Rotterdam-Rijnmond, Rotterdam, the Netherlands.
    Background: In 2016, the World Health Organisation set a goal to eliminate viral hepatitis by 2030. Robust epidemiological information underpins all efforts to achieve elimination and this systematic review provides estimates of HBsAg and anti-HCV prevalence in the European Union/European Economic Area (EU/EEA) among three at-risk populations: people in prison, men who have sex with men (MSM), and people who inject drugs (PWID).

    Methods: Estimates of the prevalence among the three risk groups included in our study were derived from multiple sources. Read More

    Poor quality data challenges conclusion and decision making: timely analysis of measles confirmed and suspected cases line list in Southern Nations Nationalities and People's Region, Ethiopia.
    BMC Infect Dis 2018 02 12;18(1):77. Epub 2018 Feb 12.
    Health research and technology transfer support process, Southern nations nationalities and people's regional health bureau, Hawassa, Ethiopia.
    Background: Measles is one of the leading causes of death among young children even though a safe and cost-effective vaccine is available. Timely analysis of measles surveillance data is crucial for epidemic control and can show disease control program status. Therefore, this study aimed to show vaccination status and delay in seeking health care using surveillance data. Read More

    SESOTHO trial ("Switch Either near Suppression Or THOusand") - switch to second-line versus WHO-guided standard of care for unsuppressed patients on first-line ART with viremia below 1000 copies/mL: protocol of a multicenter, parallel-group, open-label, randomized clinical trial in Lesotho, Southern Africa.
    BMC Infect Dis 2018 02 12;18(1):76. Epub 2018 Feb 12.
    Clinical Research Unit, Department of Medicine, Swiss Tropical and Public Health Institute, Socinstrasse 57, 4051, Basel, Switzerland.
    Background: The World Health Organization (WHO) recommends viral load (VL) measurement as the preferred monitoring strategy for HIV-infected individuals on antiretroviral therapy (ART) in resource-limited settings. The new WHO guidelines 2016 continue to define virologic failure as two consecutive VL ≥1000 copies/mL (at least 3 months apart) despite good adherence, triggering switch to second-line therapy. However, the threshold of 1000 copies/mL for defining virologic failure is based on low-quality evidence. Read More

    Comparison of hepatitis E virus seroprevalence between HBsAg-positive population and healthy controls in Shandong province, China.
    BMC Infect Dis 2018 02 12;18(1):75. Epub 2018 Feb 12.
    Academy of Preventive Medicine, Shandong University, Jinan, China.
    Background: Persons with chronic hepatitis B (CHB) infection were reported to suffer severe disease after hepatitis E virus (HEV) superinfection, but the studies regarding HEV seroprevalence in this population were limited. A recent study in Vietnam found higher HEV seroprevalence among CHB patients compared with healthy controls.

    Methods: A community-based case-control study was conducted in two counties of Shandong province, China, where hepatitis E incidence was at the highest (Rushan) and lowest (Zhangqiu) in the province based on data from routine public health surveillance. Read More

    Rationale, design, and methodology of a trial evaluating three models of care for HCV treatment among injection drug users on opioid agonist therapy.
    BMC Infect Dis 2018 02 9;18(1):74. Epub 2018 Feb 9.
    Department of Medicine, University of South Carolina School of Medicine-Greenville, Greenville, South Carolina, USA.
    Background: People who inject drugs (PWID) constitute 60% of the approximately 5 million people in the U.S. infected with hepatitis C virus (HCV). Read More

    A case report of Tubo-ovarian abscess caused by Burkholderia pseudomallei.
    BMC Infect Dis 2018 02 8;18(1):73. Epub 2018 Feb 8.
    Division of Infectious Disease, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama VI Road, Ratchathewi, Bangkok, 10400, Thailand.
    Background: Melioidosis, the disease caused by Burkholderia pseudomallei is endemic in the Northeastern part of Thailand, South-East Asia, and Northern Australia. The pelvic involvement of disease is rare even in an endemic area. Therefore, we describe in this report the clinical presentation, management, and outcome of the patient with primary tubo-ovarian abscess due to melioidosis. Read More

    Risk factors associated with cluster size of Mycobacterium tuberculosis (Mtb) of different RFLP lineages in Brazil.
    BMC Infect Dis 2018 02 8;18(1):71. Epub 2018 Feb 8.
    Laboratório de Epidemiologia da Universidade Federal do Espírito Santo, Av. Marechal Campos, 1468- Maruípe-, Vitória, ES, Brazil.
    Background: Tuberculosis (TB) transmission is influenced by patient-related risk, environment and bacteriological factors. We determined the risk factors associated with cluster size of IS6110 RFLP based genotypes of Mycobacterium tuberculosis (Mtb) isolates from Vitoria, Espirito Santo, Brazil.

    Methods: Cross-sectional study of new TB cases identified in the metropolitan area of Vitoria, Brazil between 2000 and 2010. Read More

    Comparison of the prevalence of respiratory viruses in patients with acute respiratory infections at different hospital settings in North China, 2012-2015.
    BMC Infect Dis 2018 02 8;18(1):72. Epub 2018 Feb 8.
    MOH Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, 100730, People's Republic of China.
    Background: Acute respiratory infections (ARIs) are a great public health challenge globally. The prevalence of respiratory viruses in patients with ARIs attending at different hospital settings is fully undetermined.

    Methods: Laboratory-based surveillance for ARIs was conducted at inpatient and outpatient settings of 11 hospitals in North China. Read More

    Transmission dynamics for Methicilin-resistant Staphalococous areus with injection drug user.
    BMC Infect Dis 2018 02 7;18(1):69. Epub 2018 Feb 7.
    Department of Ecology and Evolutionary Biology, University of Kansas, Lawrence, 66045, KS, USA.
    Background: Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial pathogen resistance to antibiotics including methicillin. The resistance first emerged in 1960 in a healthcare setting only after two years of using methicillin as a viable treatment for methicillin-susceptible Staphylococcus aureus. MRSA leads to infections in different parts of the body including the skin, bloodstream, lungs, or the urinary tract. Read More

    Late-onset postoperative Mycobacterium haemophilum endophthalmitis masquerading as inflammatory uveitis: a case report.
    BMC Infect Dis 2018 02 7;18(1):70. Epub 2018 Feb 7.
    Department of Ophthalmology, Faculty of Medicine, Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkok Noi, Bangkok, 10700, Thailand.
    Background: Although atypical mycobacteria had been increasingly found in various ocular infections in the past decades, a slow-growing Mycobacterium haemophilum (M. haemophilum) was scarcely reported. Similar to tuberculous infection, the presentation can masquerade as low-grade granulomatous intraocular inflammation with partial response to corticosteroids. Read More

    Microbial contaminants isolated from items and work surfaces in the post- operative ward at Kawolo general hospital, Uganda.
    BMC Infect Dis 2018 02 6;18(1):68. Epub 2018 Feb 6.
    Department of Medical Microbiology, International Health Sciences University, P.O. Box 7782, Kampala, Uganda.
    Background: Nosocomial infections are a major setback in the healthcare delivery system especially in developing countries due to the limited resources. The roles played by medical care equipment and work surfaces in the transmission of such organisms have inevitably contributed to the elevated mortality, morbidity and antibiotic resistances.

    Methods: A total 138 samples were collected during the study from Kawolo general hospital. Read More

    Estimation of the incidence of severe fever with thrombocytopenia syndrome in high endemic areas in China: an inpatient-based retrospective study.
    BMC Infect Dis 2018 02 5;18(1):66. Epub 2018 Feb 5.
    National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, 155 Changbai Road, Changping District, Beijing, 102206, People's Republic of China.
    Background: Severe fever with thrombocytopenia syndrome (SFTS) is a severe viral disease caused by SFTSV. It is important to estimate the rate of missed SFTS diagnosis and to further understand the actual incidence in high endemic areas in China.

    Methods: This study was conducted in two high SFTS endemic provinces in 2015. Read More

    Diabetes and the occurrence of infection in primary care: a matched cohort study.
    BMC Infect Dis 2018 02 5;18(1):67. Epub 2018 Feb 5.
    School of Pharmacy, Health Sciences Centre, Memorial University of Newfoundland, St. John's, A1B 3V6, Newfoundland and Labrador, Canada.
    Background: People with diabetes may be at higher risk for acquiring infections through both glucose-dependent and biologic pathways independent of glycemic control. Our aim was to estimate the association between diabetes and infections occurring in primary care.

    Methods: Using the Newfoundland and Labrador Sentinel of the Canadian Primary Care Sentinel Surveillance Network, patients with diabetes ≥18 years between 1 January 2008 and 31 March 2013 were included with at least 1-year of follow-up. Read More

    Characteristics of diarrheagenic Escherichia coli among children under 5 years of age with acute diarrhea: a hospital based study.
    BMC Infect Dis 2018 02 1;18(1):63. Epub 2018 Feb 1.
    Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jiefang Road, Wuhan, 430030, China.
    Background: Diarrhea is the leading infectious cause of childhood morbidity and mortality. Among bacterial agents, diarrheagenic Escherichia coli (DEC) is the major causal agent of childhood diarrhea in developing countries, particularly in children under the age of 5 years. Here, we performed a hospital-based prospective study to explore the pathotype distribution, epidemiological characteristics and antibiotic resistance patterns of DEC from < 5-year-old diarrheal children. Read More

    Reduction in HIV community viral loads following the implementation of a "Treatment as Prevention" strategy over 2 years at a population-level among men who have sex with men in Hangzhou, China.
    BMC Infect Dis 2018 02 1;18(1):62. Epub 2018 Feb 1.
    Zhejiang Provincial Center for Disease Control and Prevention, No. 3399 Bin Sheng Road, Binjiang District, Hangzhou, Zhejiang Province, People's Republic of China.
    Background: Previous studies have shown that the increased coverage of antiretroviral therapy (ART) could reduce the community viral load (CVL) and reduce the occurrence of new HIV infections. However, the impact on the reduction of HIV transmission among men who have sex with men (MSM) is much less certain. The frequency of HIV infections in MSM have been rapidly increasing in recent years in Hangzhou, China. Read More

    Acute biliary events during anti-tuberculosis treatment: hospital case series and a nationwide cohort study.
    BMC Infect Dis 2018 02 1;18(1):64. Epub 2018 Feb 1.
    Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan.
    Background: Tuberculosis (TB) remains one of the major infectious diseases worldwide. Adverse reactions are common during TB treatment. Few reports, however, are available on treatment-related acute biliary events (ABEs), such as cholelithiasis, biliary obstruction, acute cholecystitis, and cholangitis. Read More

    Probiotics and infective endocarditis in patients with hereditary hemorrhagic telangiectasia: a clinical case and a review of the literature.
    BMC Infect Dis 2018 02 1;18(1):65. Epub 2018 Feb 1.
    National Institute for Infectious Diseases "Lazzaro Spallanzani" IRCCS, Rome, Italy.
    Background: In the last decades, probiotics have been widely used as food supplements because of their putative beneficial health effects. They are generally considered safe but rare reports of serious infections caused by bacteria included in the definition of probiotics raise concerns on their potential pathogenic role in patients with particular predisposing factors. Patients with hereditary hemorrhagic telangiectasia (HHT) are exposed to infections because of telangiectasias and arteriovenous malformations (AVMs). Read More

    Co-circulation and simultaneous co-infection of dengue, chikungunya, and zika viruses in patients with febrile syndrome at the Colombian-Venezuelan border.
    BMC Infect Dis 2018 01 30;18(1):61. Epub 2018 Jan 30.
    Grupo de Investigación en Ciencias Animales-GRICA, Universidad Cooperativa de Colombia, Calle 30A #, 33-51, Bucaramanga, Colombia.
    Background: In Colombia, the dengue virus (DENV) has been endemic for decades, and with the recent entry of the chikungunya virus (CHIKV) (2014) and the Zika virus (ZIKV) (2015), health systems are overloaded because the diagnosis of these three diseases is based on clinical symptoms, and the three diseases share a symptomatology of febrile syndrome. Thus, the objective of this study was to use molecular methods to identify their co-circulation as well as the prevalence of co-infections, in a cohort of patients at the Colombian-Venezuelan border.

    Methods: A total of 157 serum samples from patients with febrile syndrome consistent with DENV were collected after informed consent and processed for the identification of DENV (conventional PCR and real-time PCR), CHIKV (conventional PCR), and ZIKV (real-time PCR). Read More

    Comparison of the efficacy of nafcillin and glycopeptides as definitive therapy for patients with methicillin-susceptible Staphylococcus aureus bacteremia: a retrospective cohort study.
    BMC Infect Dis 2018 01 30;18(1):60. Epub 2018 Jan 30.
    Department of Internal Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, 03722, Seoul, Republic of Korea.
    Background: Studies have shown that the prognosis of the treatment of methicillin-susceptible S. aureus (MSSA) with glycopeptides is inferior compared to treatment with β-lactam. However, there are only few studies comparing treatment with antistaphylococcal penicillin alone to glycopeptide treatment. Read More

    Late presentation for HIV care in Southwest Ethiopia in 2003-2015: prevalence, trend, outcomes and risk factors.
    BMC Infect Dis 2018 01 30;18(1):59. Epub 2018 Jan 30.
    Public Health, Flinders University, Adelaide, Australia.
    Background: Early presentation for HIV care is vital as an initial tread in the UNAIDS 90-90-90 targets. However, late presentation for HIV care (LP) challenges achieving the targets. This study assessed the prevalence, trends, outcomes and risk factorsfor LP. Read More

    The global switch from trivalent oral polio vaccine (tOPV) to bivalent oral polio vaccine (bOPV): facts, experiences and lessons learned from the south-south zone; Nigeria, April 2016.
    BMC Infect Dis 2018 01 27;18(1):57. Epub 2018 Jan 27.
    World Health organization (WHO) Nigeria Country office, UN House, plot 617/618, Diplomatic Drive, Central Business District, Abuja, Garki, PMB 2861, Nigeria.
    Background: The globally synchronized switch from trivalent Oral Polio Vaccine (tOPV) to bivalent Oral Polio Vaccine (bOPV) took place in Nigeria on April 18th 2016. The country is divided into six geopolitical zones. This study reports the experiences and lessons learned from the switch process in the six states that make up Nigeria's south-south geopolitical zone. Read More

    Case report: a fatal case of disseminated adenovirus infection in a non-transplant adult haematology patient.
    BMC Infect Dis 2018 01 27;18(1):58. Epub 2018 Jan 27.
    Clinical Microbiology, Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust, Level 5 Sandringham Building, Leicester Royal Infirmary, Infirmary Square, Leicester, LE1 5WW, UK.
    Background: We report a fatal case of disseminated adenovirus infection in a non-transplant haematology adult patient with chronic lymphocytic leukaemia who had completed combination chemoimmunotherapy a few months before developing respiratory symptoms. In such non-transplant patients, monitoring for adenovirus in the blood is not routine. However, with adenoviruses, when there is a more peripheral (i. Read More

    Empiric antibiotic therapy in urinary tract infection in patients with risk factors for antibiotic resistance in a German emergency department.
    BMC Infect Dis 2018 01 26;18(1):56. Epub 2018 Jan 26.
    Second Department of Internal Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer Ufer 1-3, D-68167, Mannheim, Germany.
    Background: The aim of this study was to identify clinical risk factors for antimicrobial resistances and multidrug resistance (MDR) in urinary tract infections (UTI) in an emergency department in order to improve empirical therapy.

    Methods: UTI cases from an emergency department (ED) during January 2013 and June 2015 were analyzed. Differences between patients with and without resistances towards Ciprofloxacin, Piperacillin with Tazobactam (Pip/taz), Gentamicin, Cefuroxime, Cefpodoxime and Ceftazidime were analyzed with Fisher's exact tests. Read More

    Case report: mechanisms of HIV elite control in two African women.
    BMC Infect Dis 2018 01 25;18(1):54. Epub 2018 Jan 25.
    Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
    Background: The majority of people living with HIV require antiretroviral therapy (ART) for controlling viral replication, however there are rare HIV controllers who spontaneously and durably control HIV in the absence of treatment. Understanding what mediates viral control in these individuals has provided us with insights into the immune mechanisms that may be important to induce for a vaccine or functional cure for HIV. To date, few African elite controllers from high incidence settings have been described. Read More

    A complex scenario of tuberculosis transmission is revealed through genetic and epidemiological surveys in Porto.
    BMC Infect Dis 2018 01 25;18(1):53. Epub 2018 Jan 25.
    Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Gualtar Campus, 4710-057, Braga, Portugal.
    Background: Tuberculosis (TB) incidence is decreasing worldwide and eradication is becoming plausible. In low-incidence countries, intervention on migrant populations is considered one of the most important strategies for elimination. However, such measures are inappropriate in European areas where TB is largely endemic, such as Porto in Portugal. Read More

    Characterization of Staphylococcus aureus isolated from patients with burns in a regional burn center, Southeastern China.
    BMC Infect Dis 2018 01 25;18(1):51. Epub 2018 Jan 25.
    Department of respiration, The first Affiliated Hospital of Nanchang University, Nanchang, 330006, China.
    Background: S.aureus is a predominant pathogen that causes infection in critically ill patients, but little information exists regarding the characterization of S. aureus from different sources in burn patients in southeastern China. Read More

    Cost-effectiveness of increasing vaccination in high-risk adults aged 18-64 Years: a model-based decision analysis.
    BMC Infect Dis 2018 01 25;18(1):52. Epub 2018 Jan 25.
    Department of Family Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
    Background: Adults aged 18-64 years with comorbid conditions are at high risk for complications of certain vaccine-preventable diseases, including influenza and pneumococcal disease. The 4 Pillars™ Practice Transformation Program (4 Pillars Program) increases uptake of pneumococcal polysaccharide vaccine, influenza vaccine and tetanus-diphtheria-acellular pertussis vaccine by 5-10% among adults with high-risk medical conditions, but its cost-effectiveness is unknown.

    Methods: A decision tree model estimated the cost-effectiveness of implementing the 4 Pillars Program in primary care practices compared to no program for a population of adults 18-64 years of age at high risk of illness complications over a 10 year time horizon. Read More

    Place of death for people with HIV: a population-level comparison of eleven countries across three continents using death certificate data.
    BMC Infect Dis 2018 01 25;18(1):55. Epub 2018 Jan 25.
    End-of-Life Care Research Group, Vrije Universiteit Brussel (VUB) & Ghent University, Brussels, Belgium.
    Background: With over 1 million HIV-related deaths annually, quality end-of-life care remains a priority. Given strong public preference for home death, place of death is an important consideration for quality care. This 11 country study aimed to i) describe the number, proportion of all deaths, and demographics of HIV-related deaths; ii) identify place of death; iii) compare place of death to cancer patients iv), determine patient/health system factors associated with place of HIV-related death. Read More

    Study on the persistence of Zika virus (ZIKV) in body fluids of patients with ZIKV infection in Brazil.
    BMC Infect Dis 2018 01 22;18(1):49. Epub 2018 Jan 22.
    World Health Organization, Geneva, Switzerland.
    Background: Zika virus (ZIKV) has been identified in several body fluids of infected individuals. In most cases, it remained detected in blood from few days to 1 week after the onset of symptoms, and can persist longer in urine and in semen. ZIKV infection can have dramatic consequences such as microcephaly and Guillain-Barré syndrome. Read More

    Guillain-Barre syndrome caused by hepatitis E infection: case report and literature review.
    BMC Infect Dis 2018 01 23;18(1):50. Epub 2018 Jan 23.
    Zhejiang University First Affiliated Hospital State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Hangzhou, Zhejiang, China.
    Background: Hepatitis E infection is a global disorder that causes substantial morbidity. Numerous neurologic illnesses, including Guillain-Barre syndrome (GBS), have occurred in patients with hepatitis E virus (HEV) infection.

    Case Presentation: We report a 58 year-old non-immunocompromised man who presented with progressive muscle weakness in all extremities during an episode of acute HEV infection, which was confirmed by measuring the anti-HEV IgM antibodies in the serum. Read More

    Characterization of Salmonella enterica from invasive bloodstream infections and water sources in rural Ghana.
    BMC Infect Dis 2018 01 19;18(1):47. Epub 2018 Jan 19.
    Infectious Disease Epidemiology, Bernhard Nocht Institute for Tropical Medicine (BNITM), Bernhard-Nocht-Str. 74, D-20359, Hamburg, Germany.
    Background: Non-typhoidal Salmonella (NTS) cause the majority of bloodstream infections in Ghana, however the mode of transmission and source of invasive NTS in Africa are poorly understood. This study compares NTS from water sources and invasive bloodstream infections in rural Ghana.

    Methods: Blood from hospitalised, febrile children and samples from drinking water sources were analysed for Salmonella spp. Read More

    Risk factors for Mycobacterium ulcerans infection (Buruli Ulcer) in Togo ─ a case-control study in Zio and Yoto districts of the maritime region.
    BMC Infect Dis 2018 01 19;18(1):48. Epub 2018 Jan 19.
    Ecole Supérieure des Techniques Biologiques et Alimentaires (ESTBA), Laboratoire des Sciences Biologiques et des Substances Bioactives, Université de Lomé, Lomé, Togo.
    Background: Buruli ulcer (BU) is a neglected mycobacterial skin infection caused by Mycobacterium ulcerans. This disease mostly affects poor rural populations, especially in areas with low hygiene standards and sanitation coverage. The objective of this study was to identify these risk factors in the districts of Zio and Yoto of the Maritime Region in Togo. Read More

    Knowledge, attitudes and practices on Schistosomiasis in sub-Saharan Africa: a systematic review.
    BMC Infect Dis 2018 01 18;18(1):46. Epub 2018 Jan 18.
    School of Nursing and Public Health, College of Health Sciences, University of KwaZulu-Natal, Howard Campus, Durban, South Africa.
    Background: Schistosomiasis remains a global health problem with an estimated 250 million people in 78 countries infected, of whom 85% live in Sub-Saharan Africa. Preventive chemotherapy remains the key public health strategy to combat schistosomiasis worldwide. Recently the WHO emphasized on the use of integrative approaches in the control and elimination of schistosomiasis. Read More

    Antimicrobial resistance of Neisseria gonorrhoeae in Germany: low levels of cephalosporin resistance, but high azithromycin resistance.
    BMC Infect Dis 2018 01 17;18(1):44. Epub 2018 Jan 17.
    Department for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
    Background: The widespread antimicrobial resistance of Neisseria gonorrhoeae is a serious problem for the treatment and control of gonorrhoea. Many of the previously effective therapeutic agents are no longer viable. Because N. Read More

    An appraisal: how notifiable infectious diseases are reported by Hungarian family physicians.
    BMC Infect Dis 2018 01 17;18(1):45. Epub 2018 Jan 17.
    Faculty of Public Health, Department Family and Occupational Medicine, University of Debrecen, Debrecen, Hungary.
    Background: Within the frame of National Epidemiological Surveillance System, family physicians have an obligation to report infections and suspicions cases. The aim of this study was to evaluate the knowledge, attitudes, daily practice and the reporting activities of Hungarian family physicians regarding to infectious diseases.

    Methods: A self-administered survey was developed, validated and used. Read More

    Estimating the scale of chronic hepatitis C virus infection in the EU/EEA: a focus on migrants from anti-HCV endemic countries.
    BMC Infect Dis 2018 01 16;18(1):42. Epub 2018 Jan 16.
    Division of Infectious Disease Control, Municipal Public Health Service Rotterdam-Rijnmond, PO Box 70032, 3000, LP, Rotterdam, The Netherlands.
    Background: Increasing the proportion diagnosed with and on treatment for chronic hepatitis C (CHC) is key to the elimination of hepatitis C in Europe. This study contributes to secondary prevention planning in the European Union/European Economic Area (EU/EEA) by estimating the number of CHC (anti-HCV positive and viraemic) cases among migrants living in the EU/EEA and born in endemic countries, defining the most affected migrant populations, and assessing whether country of birth prevalence is a reliable proxy for migrant prevalence.

    Methods: Migrant country of birth and population size extracted from statistical databases and anti-HCV prevalence in countries of birth and in EU/EEA countries derived from a systematic literature search were used to estimate caseload among and most affected migrants. Read More

    In vitro antimicrobial susceptibility testing of human Brucella melitensis isolates from Ulanqab of Inner Mongolia, China.
    BMC Infect Dis 2018 01 16;18(1):43. Epub 2018 Jan 16.
    College of Veterinary Medical Inner Mongolia Agriculture University, Hohhot, 010018, China.
    Background: Brucellosis is an endemic disease in the Inner Mongolia Autonomous Region of China and Ulanqab exhibits the highest prevalence of brucellosis in this region. Due to the complex nature of Brucellosis, a cure for this disease has proven to be elusive. Furthermore, the reduced susceptibility of Brucella spp. Read More

    Anemia in people on second line antiretroviral treatment in Lilongwe, Malawi: a cross-sectional study.
    BMC Infect Dis 2018 01 15;18(1):39. Epub 2018 Jan 15.
    UNC Project, Tidziwe Centre, Private Bag, A-104, Lilongwe, Malawi.
    Background: Anemia is common among people living with HIV infection and is frequently associated with poor quality of life and poor prognosis. It has been well described in antiretroviral naïve individuals and those on non-nucleoside reverse transcriptase inhibitor-based first line antiretroviral therapy (ART) regimens. However there is limited information on anemia for ART experienced individuals on protease inhibitor-based second line ART regimens in resource limited settings. Read More

    Self-reported genital warts among sexually-active university students: a cross-sectional study.
    BMC Infect Dis 2018 01 15;18(1):41. Epub 2018 Jan 15.
    Department of Cardiac, Thoracic and Vascular Sciences, Public Health Unit, University of Padua, Padua, Italy.
    Background: Genital warts are one of the most common forms of sexually-transmitted disease, but their epidemiology has yet to be thoroughly elucidated. The present study was designed to shed light on the prevalence of clinically-confirmed, self-reported genital warts (GWs) in a representative sample of the university population.

    Methods: In 2015, a cross-sectional survey was conducted on 11,096 individuals approached at the Students Information Bureau where they came to enroll for a university degree course. Read More

    A rare case of pericarditis and pleural empyema secondary to transdiaphragmatic extension of pyogenic liver abscess.
    BMC Infect Dis 2018 01 15;18(1):40. Epub 2018 Jan 15.
    Department of Internal Medicine, Chonnam National University Hospital, Gwangju, South Korea.
    Background: Transdiaphragmatic extension of pyogenic liver abscess is the rarest cause of pericarditis and pleural empyema. It is a rapidly progressive and highly lethal infection with mortality rates reaching 100% if left untreated. However, the transmission route, treatment methods and prognosis have not been well studied. Read More

    Monitoring vaccine and non-vaccine HPV type prevalence in the post-vaccination era in women living in the Basilicata region, Italy.
    BMC Infect Dis 2018 01 15;18(1):38. Epub 2018 Jan 15.
    Franchise Development, Sanofi-Pasteur MSD, 162 avenue Jean-Jaurès, CS 50712 69367, Cedex 07, Lyon, France.
    Background: A large free-of-charge quadrivalent HPV (qHPV) vaccination program, covering four cohorts annually (women 11, 14, 17 and 24 years), has been implemented in Basilicata since 2007. This study evaluated vaccine and non-vaccine HPV prevalence 5-7 years post-vaccination program implementation in vaccinated and unvaccinated women.

    Methods: This population-based, cross-sectional study was conducted in the public screening centers of the Local Health Unit in Matera between 2012 and 2014. Read More

    Transmission of measles among healthcare Workers in Hospital W, Xinjiang Autonomous Region, China, 2016.
    BMC Infect Dis 2018 01 12;18(1):36. Epub 2018 Jan 12.
    Chinese Center for Disease Control and Prevention, No.27, Nanwei Road, Xicheng District, Beijing, 100050, China.
    Background: As China approaches the elimination of measles, outbreaks of measles continue to occur. Healthcare workers (HCWs) are known to be at high risk of infection and transmission of measles virus. A measles outbreak occurred in a hospital in Xinjiang Uighur Autonomous Region of the People's Republic of China. Read More

    Eikenella corrodens endocarditis and liver abscess in a previously healthy male, a case report.
    BMC Infect Dis 2018 01 12;18(1):35. Epub 2018 Jan 12.
    Department of Infectious Diseases, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
    Background: Eikenella corrodens is one of the HACEK bacteria constituting part of the normal flora of the oropharynx, however, still an uncommon pathogen. We report a case of a large Eikenella corrodens liver abscess with simultaneously endocarditis in a previously healthy male.

    Case Presentation: A 49-year-old Danish man was admitted because of one-month malaise, fever, cough and unintentional weight loss. Read More

    Landscape and rodent community composition are associated with risk of hemorrhagic fever with renal syndrome in two cities in China, 2006-2013.
    BMC Infect Dis 2018 01 12;18(1):37. Epub 2018 Jan 12.
    State Key Laboratory of Remote Sensing Science, College of Global Change and Earth System Science, Beijing Normal University, Beijing, 100875, China.
    Background: Hemorrhagic fever with renal syndrome (HFRS) is a rodent-borne disease caused by hantaviruses. Landscape can influence the risk of hantavirus infection for humans, mainly through its effect on rodent community composition and distribution. It is important to understand how landscapes influence population dynamics for different rodent species and the subsequent effect on HFRS risk. Read More

    1 OF 115