6,660 results match your criteria BMC Infectious Diseases[Journal]


Invasive Salmonella infections among children in Bintulu, Sarawak, Malaysian Borneo: a 6-year retrospective review.

BMC Infect Dis 2019 Apr 18;19(1):330. Epub 2019 Apr 18.

Institute of Health and Community Medicine, Universiti Malaysia Sarawak, Kota Samarahan, Sarawak, Malaysia.

Background: Invasive Salmonella infections result in significant morbidity and mortality in developing countries. In Asia, typhoid and paratyphoid fever are reported to be the major invasive Salmonella infections, while invasive non-typhoidal Salmonella (iNTS) infections are believed to be uncommon. Data from Sarawak, in Malaysian Borneo, are limited. Read More

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http://dx.doi.org/10.1186/s12879-019-3963-xDOI Listing

The double-edged sword - prosthetic joint infection following BCG treatment for bladder cancer: a case report.

BMC Infect Dis 2019 Apr 18;19(1):331. Epub 2019 Apr 18.

Department of Medical Microbiology and Immunology, University of California - Davis, University of California Davis Medical Center, Sacramento, CA, USA.

Background: Prosthetic joint infections remain a significant cause of morbidity and are frustrating for patients and physicians alike. Unusual causes of infection may be seen in selected circumstances and a high index of suspicion and a careful history are required to ensure an accurate and timely diagnosis can be made.

Case Presentation: We present a case of Mycobacterium bovis prosthetic joint infection secondary to intravesicular Bacillus Calmette-Guérin (BCG) treatment for prior bladder cancer definitively identified by spoligotyping. Read More

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http://dx.doi.org/10.1186/s12879-019-3951-1DOI Listing

Direct-acting antivirals and visceral leishmaniasis: a case report.

BMC Infect Dis 2019 Apr 18;19(1):328. Epub 2019 Apr 18.

Dipartimento di Scienze per la promozione della Salute e Materno-infantile, Università di Palermo, Palermo, Italy.

Background: Visceral leishmaniasis is a vector-borne parasitic disease caused by protozoa belonging to the genus Leishmania. The clinical presentation of visceral leishmaniasis strictly depends on the host immunocompetency, whereas depressive conditions of the immune system impair the capability to resolve the infection and allow reactivation from sites of latency of the parasite.

Case Presentation: We describe a case of visceral leishmaniasis (VL) that occurred in a patient with chronic hepatitis C treated with direct-acting antiviral drugs (DAA). Read More

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12879-019-3947-xDOI Listing
April 2019
1 Read

Sero-epidemiological status and risk factors of toxoplasmosis in pregnant women in Northern Vietnam.

BMC Infect Dis 2019 Apr 18;19(1):329. Epub 2019 Apr 18.

Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820, Merelbeke, Belgium.

Background: In Vietnam, few studies have determined the epidemiological status of toxoplasmosis in pregnant women and no routine prenatal screening is in place. This study was conducted to evaluate the seroprevalence of this zoonotic parasitic infection in pregnant women in Northern Vietnam and to assess the association with awareness, risk factors and congenital toxoplasmosis.

Methods: Approximately 800 pregnant women were included in the study from two hospitals, one in Hanoi and one in Thai Binh province, which is known to have a dense cat population. Read More

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12879-019-3885-7DOI Listing
April 2019
1 Read

Listeria monocytogenes infectious periaortitis: a case report from the infectious disease standpoint.

BMC Infect Dis 2019 Apr 16;19(1):326. Epub 2019 Apr 16.

Bacteriology Laboratory, Department of Genetics and Laboratory Medicine, Geneva University Hospitals, rue Gabrielle Perret-Gentil 4, 1211, Geneva 14, Switzerland.

Background: Endograft infection is a rare but extremely dangerous complication of aortic repair (25-100% of mortality). We describe here the first case of Listeria monocytogenes abdominal periaortitis associated with a vascular graft. We also discuss the differential diagnosis of periaortitis and provide a literature review of L. Read More

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http://dx.doi.org/10.1186/s12879-019-3953-zDOI Listing
April 2019
3 Reads

Prevalence of group B streptococcus among pregnant women and newborns at Hawassa University comprehensive specialized hospital, Hawassa, Ethiopia.

BMC Infect Dis 2019 Apr 16;19(1):325. Epub 2019 Apr 16.

Department of Pediatrics, College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia.

Background: Group B streptococcus (GBS) is reported as the leading cause of neonatal sepsis and meningitis. Newborns from GBS colonized pregnant women are at high risk of infection.

Method: A Hospital based cross-sectional study was conducted at Hawassa University Comprehensive Specialized Hospital from November 05, 2014 to March 25, 2015. Read More

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http://dx.doi.org/10.1186/s12879-019-3859-9DOI Listing

Seroprevalence and risk factors of Toxoplasma gondii among pregnant women in Adwa district, northern Ethiopia.

BMC Infect Dis 2019 Apr 16;19(1):327. Epub 2019 Apr 16.

Department of Public Health, College of Health Sciences, Aksum University, Aksum, Ethiopia.

Background: Toxoplasma gondii infection is a great health concern to pregnant women and the developing fetus. The aim of this study was to determine the seroprevalence of T. gondii and its associated factors in Adwa district. Read More

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12879-019-3936-0DOI Listing
April 2019
1 Read

Diagnostic value of the interferon-γ release assay for tuberculosis infection in patients with Behçet's disease.

BMC Infect Dis 2019 Apr 15;19(1):323. Epub 2019 Apr 15.

Department of Rheumatology and Clinical Immunology, Key Laboratory of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Ministry of Education, Beijing, China.

Background: To investigate the diagnostic value of the interferon-γ release assay (IGRA) for detecting tuberculosis (TB) infection in patients with Behçet's disease (BD).

Methods: We retrospective analyzed the data collected from 173 BD patients hospitalized between 2010 and 2015. Ninety-nine healthy volunteers were enrolled as a control group. Read More

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http://dx.doi.org/10.1186/s12879-019-3954-yDOI Listing

Risk factors for death among children 0-59 months of age with moderate-to-severe diarrhea in Manhiça district, southern Mozambique.

BMC Infect Dis 2019 Apr 15;19(1):322. Epub 2019 Apr 15.

Centro de Investigação em Saúde de Manhiça (CISM), Rúa 12, Vila da Manhiça, 1929, Maputo, CP, Mozambique.

Background: Despite major improvements in child survival rates, the number of deaths due to diarrhea remains unacceptably high. We aimed to describe diarrhea-associated mortality and evaluate risk factors for death among Mozambican children with moderate-to-severe diarrhea (MSD).

Methods: Between December 2007 and November 2012, children under-five with MSD were enrolled in Manhiça district, as part of the Global Enteric Multicenter study (GEMS). Read More

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http://dx.doi.org/10.1186/s12879-019-3948-9DOI Listing
April 2019
1 Read

Prevalence and determinants of persistent symptoms after treatment for Lyme borreliosis: study protocol for an observational, prospective cohort study (LymeProspect).

BMC Infect Dis 2019 Apr 15;19(1):324. Epub 2019 Apr 15.

National Institute for Public Health and Environment (RIVM), Center for Infectious Disease Control, P.O. Box 1, 3720, BA, Bilthoven, the Netherlands.

Background: After antibiotic treatment of Lyme borreliosis, a subset of patients report persistent symptoms, also referred to as post-treatment Lyme disease syndrome. The reported prevalence of persistent symptoms varies considerably, and its pathophysiology is under debate. The LymeProspect study has been designed to investigate the prevalence, severity, and a wide range of hypotheses on the etiology of persistent symptoms among patients treated for Lyme borreliosis in the Netherlands. Read More

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12879-019-3949-8DOI Listing
April 2019
2 Reads

A systematic review of necrotising fasciitis in children from its first description in 1930 to 2018.

BMC Infect Dis 2019 Apr 11;19(1):317. Epub 2019 Apr 11.

Department of Paediatric Surgery, Chris Hani Baragwanath Academic Hospital, Faculty of Health Sciences, University of the Witwatersrand, 26 Chris Hani Road, Johannesburg, ZA-1860, South Africa.

Background: Necrotising fasciitis is a rapidly progressing soft-tissue infection with a low incidence that carries a relevant risk of morbidity and mortality. Although necrotising fasciitis is often fatal in adults, its case fatality rate seems to be lower in children. A highly variable clinical presentation makes the diagnosis challenging, which often results in misdiagnosis and time-delay to therapy. Read More

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http://dx.doi.org/10.1186/s12879-019-3941-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458701PMC
April 2019
1 Read

Identification of priority areas for surveillance of cutaneous leishmaniasis using spatial analysis approaches in Southeastern Brazil.

BMC Infect Dis 2019 Apr 11;19(1):318. Epub 2019 Apr 11.

Departamento de Parasitologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Av. Pres. Antônio Carlos, 6627 - Pampulha, Belo Horizonte, MG, 31270-901, Brazil.

Background: Cutaneous leishmaniasis (CL) is an important public health problem in Brazil and in several tropical regions of the world. In the Americas, Brazil is the country with the highest number of registered cases. In Brazil, the state of Minas Gerais has the highest number of cases in the southeastern region. Read More

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http://dx.doi.org/10.1186/s12879-019-3940-4DOI Listing

Human rabies post exposure prophylaxis at the Pasteur Institute of Dakar, Senegal: trends and risk factors.

BMC Infect Dis 2019 Apr 11;19(1):321. Epub 2019 Apr 11.

Pasteur Institute of Dakar, Epidemiology unit, Dakar, Senegal.

Background: Rabies remains a major public health problem in developing countries. Most fatal rabies cases, especially in children, result from dog bites and occur in low-income countries, such as those in Sub-Saharan Africa. Rabies can be controlled through mass dog vaccination and human deaths prevented through timely and appropriate post-exposure prophylaxis (PEP). Read More

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http://dx.doi.org/10.1186/s12879-019-3928-0DOI Listing
April 2019
1 Read

Severe infection increases cardiovascular risk among HIV-infected individuals.

BMC Infect Dis 2019 Apr 11;19(1):319. Epub 2019 Apr 11.

Laboratório de Pesquisa Clínica em Medicina Intensiva, Instituto Nacional de Infectologia Evandro Chagas (INI), Fundação Oswaldo Cruz (FIOCRUZ), Rio de Janeiro, Brazil.

Background: The identification and management of cardiovascular risk factors became a major clinical issue among HIV-infected individuals in the post-cART era. As in the past decades the link between acute infections and cardiovascular diseases became clear in the general population, we sorted to investigate the role of severe infections on incident cardiovascular diseases (CVDs) among HIV-infected individuals.

Methods: HIV-infected individuals aged ≥18 years, with no history of CVD were followed from January 2000 to December 2013 until the occurrence of the first CVD event, death or end of study, whichever occurred first. Read More

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http://dx.doi.org/10.1186/s12879-019-3894-6DOI Listing

Treatment outcomes of drug resistant tuberculosis patients in Morocco: multi-centric prospective study.

BMC Infect Dis 2019 Apr 11;19(1):316. Epub 2019 Apr 11.

Equipe de Recherche de Pharmacoéconomie & Pharmacoépidémiologie. Laboratoire de Pharmacologie & Toxicologie, Faculté de Médecine et de Pharmacie, Université Mohammed V, Rabat, Morocco.

Background: Drug resistant tuberculosis is a major public health problem in Morocco and worldwide. Treatment outcome of drug resistant tuberculosis is poor and requires a long period of treatment with many toxic and expensive antituberculosis drugs. The aim of this study is to evaluate treatment outcomes of drug resistant tuberculosis and to determine predictors of poor treatment outcomes in a large region of Morocco. Read More

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http://dx.doi.org/10.1186/s12879-019-3931-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458640PMC

High incidence and low case detection rate among contacts of tuberculosis cases in Shanghai, China.

BMC Infect Dis 2019 Apr 11;19(1):320. Epub 2019 Apr 11.

Department of Epidemiology, School of Public Health, Fudan University, Shanghai, China.

Background: To assess the effect of a contact investigation strategy by assessing the incidence of tuberculosis and the case detection rate among contacts of tuberculosis patients.

Methods: The pulmonary tuberculosis incidence among contacts was determined retrospectively from a tuberculosis information management system. For each detection method (symptom examination only, symptom examination plus chest radiography or other alternatives), the detection rate of pulmonary tuberculosis patients among contacts was derived from contact investigation form records. Read More

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http://dx.doi.org/10.1186/s12879-019-3942-2DOI Listing

Prevalence of hepatitis C infection, screening and associated factors among men who have sex with men attending gay venues: a cross-sectional survey (PREVAGAY), France, 2015.

BMC Infect Dis 2019 Apr 11;19(1):315. Epub 2019 Apr 11.

Department of Infectious Diseases - Santé publique France, French national public health agency, 12 rue du Val d'Osne, 94415, Saint-Maurice, Cedex, France.

Background: Over the last 20 years, Hepatitis C virus (HCV) infection prevalence has dramatically increased among HIV-infected men who have sex with men (MSM) in many countries worldwide. It is suspected that this increase is primarily driven by sexual behaviours linked to blood exposure. Monitoring these behaviours is crucial to understand the drivers of the epidemic. Read More

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http://dx.doi.org/10.1186/s12879-019-3945-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458747PMC
April 2019
4 Reads

Epidemiological and genetic characterization of pH1N1 and H3N2 influenza viruses circulated in MENA region during 2009-2017.

BMC Infect Dis 2019 Apr 11;19(1):314. Epub 2019 Apr 11.

Biomedical Research Center, Qatar University, Doha, 2713, Qatar.

Background: Influenza surveillance is necessary for detection of emerging variants of epidemiologic and clinical significance. This study describes the epidemiology of influenza types A and B, and molecular characteristics of surface glycoproteins (hemagglutinin [HA] and neuraminidase [NA]) of influenza A subtypes: pH1N1 and H3N2 circulated in Arabian Gulf, Levant and North Africa regions during 2009-2017.

Methods: Analysis of phylogenetics and evolution of HA and NA genes was done using full HA and NA sequences (n = 1229) downloaded from Influenza Research Database (IRD). Read More

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http://dx.doi.org/10.1186/s12879-019-3930-6DOI Listing

Diversity of HIV-1 genotypes and high prevalence of pretreatment drug resistance in newly diagnosed HIV-infected patients in Shanghai, China.

BMC Infect Dis 2019 Apr 8;19(1):313. Epub 2019 Apr 8.

Fudan University (Shanghai Public Health Clinical Center), Shanghai, China.

Background: Genetic variability and liability to develop drug-resistant mutations are the main characteristics of HIV-1, which can not only increase the risk of antiretroviral treatment (ART) failure, but also can lead to the spread of resistant strains. We aim to investigate the distribution of HIV-1 genotypes and prevalence of pretreatment drug resistance (PDR) in ART-naïve HIV-1 infected patients in Shanghai China.

Methods: A cross-sectional study was performed among the newly diagnosed ART-naive HIV-1 infected patients during the period from January 2017 to November 2017 in Shanghai Public Health Clinical Center. Read More

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http://dx.doi.org/10.1186/s12879-019-3927-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454613PMC
April 2019
4 Reads

Impact of early detection of acute invasive fungal rhinosinusitis in immunocompromised patients.

BMC Infect Dis 2019 Apr 5;19(1):310. Epub 2019 Apr 5.

Department of Ophthalmology, Otorhinolaryngology, and Head and Neck Surgery, Ribeirão Preto Medical School, University of São Paulo, Av. Bandeirantes, 3900 - 12° andar., São Paulo, São Paulo, CEP: 14049-900, Brazil.

Background: Early diagnosis of acute invasive fungal rhinosinusitis (AIFRS) is vital to improving outcomes in immunocompromised patients. This study evaluated the impact of a systematic protocol with nasal endoscopy and biopsies to early detect AIFRS in immunocompromised patients. Additionally, we compared the accuracy of frozen-section biopsy and culture with formalin-fixed paraffin-embedded (FFPE) biopsy. Read More

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http://dx.doi.org/10.1186/s12879-019-3938-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451285PMC
April 2019
1 Read

Health care seeking delay among pulmonary tuberculosis patients in North West zone of Tigrai region, North Ethiopia.

BMC Infect Dis 2019 Apr 5;19(1):309. Epub 2019 Apr 5.

College of medicine and health science, Adigrat University, Adigrat, Ethiopia.

Background: Tuberculosis (TB) is a major public health problem and it is among the top 10 causes of death worldwide. One of the challenges against attaining an effective TB control program is delay in seeking health care to diagnosis and treatment of TB patients. The aim of this study was to assess health care-seeking delay among pulmonary TB patients. Read More

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http://dx.doi.org/10.1186/s12879-019-3893-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451246PMC

Safety and efficacy of prophylaxis for Pneumocystis jirovecii pneumonia involving trimethoprim-sulfamethoxazole dose reduction in kidney transplantation.

BMC Infect Dis 2019 Apr 5;19(1):311. Epub 2019 Apr 5.

Kidney Transplant Program, St. Michael's Hospital, University of Toronto, 61 Queen Street East, 9th Floor, Toronto, ON, M5C 2T2, Canada.

Background: Trimethoprim-sulfamethoxazole (TMP-SMX) is the drug of choice for anti-Pneumocystis jirovecii pneumonia (PcP) prophylaxis in kidney transplant recipients (KTR). Post-transplant management balances preventing PcP with managing TMP-SMX-related adverse effects. TMP-SMX dose reduction addresses adverse effects but its implications to incident PcP are unclear. Read More

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http://dx.doi.org/10.1186/s12879-019-3944-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451305PMC
April 2019
1 Read

Retention in care and virological failure among adult HIV+ patients on second-line ART in Rwanda: a national representative study.

BMC Infect Dis 2019 Apr 5;19(1):312. Epub 2019 Apr 5.

Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, University of Basel, Spitalstrasse 12, 1st floor, CH-4031, Basel, Switzerland.

Background: Currently, there is limited evidence on the effectiveness of second-line antiretroviral therapy (ART) in sub-Saharan Africa. To address this challenge, outcomes of second-line protease inhibitor (PI) based ART in Rwanda were assessed.

Methods: A two-stage cluster sampling design was undertaken. Read More

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http://dx.doi.org/10.1186/s12879-019-3934-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451213PMC

Integrated care of severe infectious diseases to people with substance use disorders; a systematic review.

BMC Infect Dis 2019 Apr 4;19(1):306. Epub 2019 Apr 4.

Department of Addiction Medicine, Haukeland University Hospital, Bergen, Norway.

Background: Various integrated care models have been used to improve treatment completion of medications for chronic hepatitis B virus (HBV), chronic hepatitis C virus (HCV), Mycobacterium tuberculosis (TB), and Human immunodeficiency virus (HIV) among people with substance use disorders (SUD). We have conducted a systematic review to evaluate whether integrated models have impacts of the treatment of infectious diseases among marginalized people with SUD.

Methods: We searched MEDLINE/PubMed (1946 to 2018, on July 26, 2018) and Embase (from 1974 to 2018, on July 26, 2018) for randomized controlled trials (RCTs) and cohort studies evaluating diverse integrated models' effects on sustained virological response (SVR), HIV suppression, HBV curation or suppression, completion of TB treatment regimen among people with SUD. Read More

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http://dx.doi.org/10.1186/s12879-019-3918-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449980PMC
April 2019
1 Read

Prevalence of rifampicin resistant Mycobacterium tuberculosis among presumptive tuberculosis patients in selected governmental hospitals in Addis Ababa, Ethiopia.

BMC Infect Dis 2019 Apr 4;19(1):307. Epub 2019 Apr 4.

Department of internal Medicine, Yekatit 12 Hospital Medical College, P.O. Box 257, Addis Ababa, Ethiopia.

Background: Rapid detection of rifampicin resistance is essential for early management and prevention of transmission of multidrug-resistant tuberculosis (MDR-TB). We studied the prevalence of rifampicin resistance of Mycobacterium tuberculosis (MTB) among presumptive TB patients in Addis Ababa, Ethiopia.

Methods: A retrospective cross sectional study was conducted in three referral hospitals and the regional laboratory in Addis Ababa city from March 2015 to October 2017. Read More

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http://dx.doi.org/10.1186/s12879-019-3943-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449910PMC
April 2019
2 Reads

Epidemiology and burden of influenza in healthy children aged 6 to 35 months: analysis of data from the placebo arm of a phase III efficacy trial.

BMC Infect Dis 2019 Apr 4;19(1):308. Epub 2019 Apr 4.

Netherlands Institute for Health Services Research, Utrecht, The Netherlands.

Background: Despite World Health Organization recommendations, in many countries young children are not targeted for influenza vaccination. To help inform influenza vaccination policy, we examined the occurrence and burden of influenza in healthy children aged 6 to 35 months using data from a recent phase III placebo-controlled influenza vaccine trial conducted in countries in the Northern and Southern Hemispheres.

Methods: This was an analysis of data from participants included in the placebo arm of a phase III clinical trial in healthy children aged 6 to 35 months (EudraCT no. Read More

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http://dx.doi.org/10.1186/s12879-019-3920-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449994PMC
April 2019
3 Reads

Using country of origin to inform targeted tuberculosis screening in asylum seekers: a modelling study of screening data in a German federal state, 2002-2015.

BMC Infect Dis 2019 Apr 3;19(1):304. Epub 2019 Apr 3.

Institute of Medical Biometry and Informatics (IMBI), University Hospital Heidelberg, Heidelberg, Germany.

Background: Screening programmes for tuberculosis (TB) among immigrants rarely consider the heterogeneity of risk related to migrants' country of origin. We assess the performance of a large screening programme in asylum seekers by analysing (i) the difference in yield and numbers needed to screen (NNS) by country and WHO-reported TB burden, (ii) the possible impact of screening thresholds on sensitivity, and (iii) the value of WHO-estimated TB burden to improve the prediction accuracy of screening yield.

Methods: We combined individual data of 119,037 asylum seekers screened for TB in Germany (2002-2015) with TB estimates of the World Health Organization (WHO) (1990-2014) for their 81 countries of origin. Read More

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12879-019-3902-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448304PMC
April 2019
5 Reads

Fulminant arterial vasculitis as an unusual complication of disseminated staphylococcal disease due to the emerging CC1 methicillin-susceptible Staphylococcus aureus clone: a case report.

BMC Infect Dis 2019 Apr 3;19(1):302. Epub 2019 Apr 3.

Department of Infection, Immunity and Inflammation, Institut Cochin, INSERM U1016, Paris, EU, France.

Background: Staphylococcus aureus has emerged as a leading cause of invasive severe diseases with a high rate of morbidity and mortality worldwide. The wide spectrum of clinical manifestations and outcome observed in staphylococcal illness may be a consequence of both microbial factors and variability of the host immune response.

Case Presentation: A 14-years old child developed limb ischemia with gangrene following S. Read More

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http://dx.doi.org/10.1186/s12879-019-3933-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446405PMC

Lactococcus garvieae, an unusual pathogen in infective endocarditis: case report and review of the literature.

BMC Infect Dis 2019 Apr 3;19(1):301. Epub 2019 Apr 3.

Department of Internal Medicine, Division of Infectious Diseases, UTHealth - McGovern Medical School, Houston, TX, USA.

Background: Lactococcus garvieae is an unusual cause of infective endocarditis (IE). No current diagnostic and therapeutic guidelines are available to treat IE caused by these organisms. Based on a case report, we provide a review of the literature of IE caused by L. Read More

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http://dx.doi.org/10.1186/s12879-019-3912-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446321PMC
April 2019
2 Reads

Predictors of virological treatment failure among adult HIV patients on first-line antiretroviral therapy in Woldia and Dessie hospitals, Northeast Ethiopia: a case-control study.

BMC Infect Dis 2019 Apr 3;19(1):305. Epub 2019 Apr 3.

Department of Epidemiology, Institute of health, Jimma University, Jimma, Ethiopia.

Background: Virological treatment failure is a problem that a Human Immune Virus patient faces after starting treatment due to different factors. However, there were few studies done on the predictors of virological treatment failure among adult patients on first-line antiretroviral therapy in Ethiopia in general, and no study was done in the study area in particular. Therefore, the aim of the study was to identify predictors of virological treatment failure among adult patients on first-line antiretroviral therapy in Woldiya and Dessie Hospitals, Northeast Ethiopia. Read More

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http://dx.doi.org/10.1186/s12879-019-3924-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448227PMC
April 2019
1 Read

Incidence and microbiology of post-operative infections after radical cystectomy and ureteral stent removal; a retrospective cohort study.

BMC Infect Dis 2019 Apr 3;19(1):303. Epub 2019 Apr 3.

Radboud center for infectious diseases, Radboud university medical center, P.O. Box 9101, 6500, HB, Nijmegen, the Netherlands.

Background: Post-operative infections are frequent after radical cystectomy with urinary diversion surgery (UDS). Reduction of post-operative infections necessitates appropriate peri-operative antimicrobial prophylaxis targeting causative bacteria. We assessed the incidence and microbiology of infections in the 30-day post-operative period after UDS and investigated effectiveness of the currently used peri-operative antibacterial prophylaxis. Read More

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12879-019-3932-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448312PMC
April 2019
2 Reads

Evaluation of antimicrobial prophylaxis use and rate of surgical site infection in surgical ward of Wachemo University Nigist Eleni Mohammed Memorial Hospital, Southern Ethiopia: prospective cohort study.

BMC Infect Dis 2019 Apr 2;19(1):298. Epub 2019 Apr 2.

Ethiopian Biotechnology Institute, Addis Ababa, Ethiopia.

Background: Surgical site infection (SSI) is the foremost infection in the overall patient population, affecting up to 66% of operated patients and with a frequency up to nine times more than in developed countries. This study aimed to determine the rate, associated factors of surgical site infection, and identification of causative agents and their antimicrobial susceptibility in surgical ward of Wachemo University Nigist Eleni Mohamed Memorial Hospital (WUNEMMH), Southern Ethiopia.

Method: Prospective cohort study involving 255 patients who underwent surgical procedure in WUNEMMH from January 1 to September 1, 2017. Read More

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12879-019-3895-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446332PMC
April 2019
2 Reads

Bovine leukemia virus discovered in human blood.

BMC Infect Dis 2019 Apr 2;19(1):297. Epub 2019 Apr 2.

School of Public Health, University of California, 16 Barker Hall, Berkeley, CA, 94720-7354, USA.

Background: Bovine leukemia virus (BLV) infection is widespread in cattle globally and is present in marketed beef and dairy products. Human infection with BLV has been reported in breast and lung cancer tissues and was significantly associated with breast cancer in 3 case-control studies. The purpose of this current research was to determine if BLV is present in human blood cells and if antibodies to BLV are related to blood cell infection. Read More

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http://dx.doi.org/10.1186/s12879-019-3891-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444872PMC
April 2019
1 Read

Safety and efficacy of the combination simeprevir-sofosbuvir in HCV genotype 1- and 4-mono-infected patients from the French ANRS CO22 hepather cohort.

BMC Infect Dis 2019 Apr 2;19(1):300. Epub 2019 Apr 2.

Université Paris Descartes ; APHP, Unité d'Hépatologie, Hôpital Cochin ; INSERM U-818 et USM20, Institut Pasteur, Paris, France.

Background: Although real-life results of sofosbuvir/simeprevir have been extensively reported from the United States, data from other geographical areas are limited. In the French observational cohort, ANRS CO22 HEPATHER, 9432 patients were given the new oral antivirals from December 2013 to June 30, 2018. We report the results of sofosbuvir/simeprevir in genotypes 1- and 4-infected patients. Read More

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http://dx.doi.org/10.1186/s12879-019-3923-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446259PMC
April 2019
1 Read

Seroprevalence and incidence of primary dengue infections among children in a rural region of Maharashtra, Western India.

BMC Infect Dis 2019 Apr 2;19(1):296. Epub 2019 Apr 2.

KEM Hospital and Research Centre, Pune, 411001, India.

Background: Dengue infections have become a huge threat to public health systems in developing countries. Data on seroprevalence and incidence of dengue infections are lacking from rural regions of India. The objective of present study was to investigate the seroprevalence and incidence of dengue infection utilizing repeated serosurveys from a rural region of Maharashtra, Western India. Read More

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http://dx.doi.org/10.1186/s12879-019-3937-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444844PMC
April 2019
1 Read

First isolation and genotyping of Bartonella henselae from a cat living with a patient with cat scratch disease in Southeast Europe.

BMC Infect Dis 2019 Apr 2;19(1):299. Epub 2019 Apr 2.

Department for Bacteriology and Parasitology, Croatian Veterinary Institute, Savska cesta 143, 10000, Zagreb, Croatia.

Background: The bacterial genus Bartonella is distributed worldwide and poses a public health risk. Cat-scratch disease caused by B. henselae in Croatia was first described in 1957. Read More

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http://dx.doi.org/10.1186/s12879-019-3929-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446304PMC

Prevalence and clinical outcomes of Plasmodium falciparum and intestinal parasitic infections among children in Kiryandongo refugee camp, mid-Western Uganda: a cross sectional study.

BMC Infect Dis 2019 Apr 1;19(1):295. Epub 2019 Apr 1.

Department of Biology, Faculty of Science and Education, Busitema University, Tororo, Uganda.

Background: The prevalence of Plasmodium falciparum and Intestinal Parasitic Infections (IPIs) - with the corresponding pathogenesis among children remain uncertain. This study aimed at determining the prevalence and the outcomes (including anaemia) of the respective infections and co-infections. Anaemia is a condition in which the number of red blood cells transporting oxygen to the various body parts is not sufficient to meet the needs of the body. Read More

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http://dx.doi.org/10.1186/s12879-019-3939-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444856PMC
April 2019
1 Read

The 2018 Lebanese Society of Infectious Diseases and Clinical Microbiology Guidelines for the use of antimicrobial therapy in complicated intra-abdominal infections in the era of antimicrobial resistance.

BMC Infect Dis 2019 Mar 29;19(1):293. Epub 2019 Mar 29.

Division of Infectious Diseases, Department of Internal Medicine, Makassed General Hospital, Beirut, Lebanon.

Background: The Lebanese Society of Infectious Diseases and Clinical Microbiology (LSIDCM) is involved in antimicrobial stewardship. In an attempt at guiding clinicians across Lebanon in regards to the proper use of antimicrobial agents, members of this society are in the process of preparing national guidelines for common infectious diseases, among which are the guidelines for empiric and targeted antimicrobial therapy of complicated intra-abdominal infections (cIAI). The aims of these guidelines are optimizing patient care based on evidence-based literature and local antimicrobial susceptibility data, together with limiting the inappropriate use of antimicrobials thus decreasing the emergence of antimicrobial resistance (AMR) and curtailing on other adverse outcomes. Read More

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http://dx.doi.org/10.1186/s12879-019-3829-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441166PMC
March 2019
1 Read

Syphilis-attributable adverse pregnancy outcomes in China: a retrospective cohort analysis of 1187 pregnant women with different syphilis treatment.

BMC Infect Dis 2019 Mar 29;19(1):292. Epub 2019 Mar 29.

Division of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, 9 Jinsui Road, Guangzhou, 510623, China.

Background: Syphilis is responsible for a substantial burden of preventable adverse outcomes in pregnancy. The purpose of this study was to compare the frequency of adverse pregnancy outcomes among syphilis-seropositive women who received different treatment regimens at different times in Guangzhou, China.

Methods: Pregnant women with syphilis infection who received prenatal and delivery services in Guangzhou between January 2014 and December 2016 were included. Read More

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http://dx.doi.org/10.1186/s12879-019-3896-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439997PMC
March 2019
1 Read
2.613 Impact Factor

The epidemiology of HIV and other sexually transmitted infections in African, Caribbean and Black men in Toronto, Canada.

BMC Infect Dis 2019 Mar 29;19(1):294. Epub 2019 Mar 29.

Faculty of Medicine, University of Toronto, 1 Kings College Circle, Toronto, ON, M5S 1A8, Canada.

Background: African, Caribbean, and Black (Black) men account for 16.5% of new HIV diagnoses among men in Ontario. There is substantial evidence that sexually transmitted infections (STIs) are associated with increased likelihood of HIV infection; however, little is known regarding the prevalence of HIV/STI co-infections among Black men in Toronto. Read More

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http://dx.doi.org/10.1186/s12879-019-3925-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441217PMC
March 2019
1 Read

Epidemiological and clinical characteristics of Streptococcus tigurinus endocarditis.

BMC Infect Dis 2019 Mar 29;19(1):291. Epub 2019 Mar 29.

CIBER Enfermedades Respiratorias-CIBERES, Madrid, Spain.

Background: Streptococcus tigurinus was recently described as a new streptococcal species within the viridans group streptococci (VGS). The objectives of the present work were to analyse the clinical and microbiological characteristics of S. tigurinus isolated from patients with bacteraemias, to determine the prevalence of S. Read More

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http://dx.doi.org/10.1186/s12879-019-3914-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440093PMC
March 2019
1 Read

Development of a TaqMan Array card to target 21 purulent meningitis-related pathogens.

BMC Infect Dis 2019 Mar 28;19(1):289. Epub 2019 Mar 28.

Anhui Medical University, Hefei, China.

Background: Purulent meningitis (PM) is a serious life-threatening infection of the central nervous system (CNS) by bacteria or fungi and associated with high mortality and high incidence of CNS sequelae in children. However, the conventional cerebrospinal fluid (CSF) culture method is time-consuming and has a low sensitivity.

Methods: Our study developed a real-time PCR-based purulent meningitis-TaqMan array card (PM-TAC) that targeted 21 PM-related pathogens and could produce results within 3 h. Read More

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http://dx.doi.org/10.1186/s12879-019-3856-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438039PMC
March 2019
2 Reads
2.613 Impact Factor

Correction to: Temporal patterns of influenza A subtypes and B lineages across age in a subtropical city, during pre-pandemic, pandemic, and post-pandemic seasons.

BMC Infect Dis 2019 Mar 28;19(1):290. Epub 2019 Mar 28.

Sichuan Center for Disease Control and Prevention, No. 6 Zhongxue Road, Wuhou District, Chengdu, 610041, Sichuan, People's Republic of China.

Following publication of the original article [1], the author reported an error in the title. Read More

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http://dx.doi.org/10.1186/s12879-019-3807-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437956PMC

Clinical characteristics and managements of severe hand, foot and mouth disease caused by enterovirus A71 and coxsackievirus A16 in Shanghai, China.

BMC Infect Dis 2019 Mar 27;19(1):285. Epub 2019 Mar 27.

Department of Pediatrics, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, 1665 Kongjiang Road, Shanghai, 200092, China.

Background: Hand, foot and mouth disease (HFMD) is a transmissible infectious disease caused by human enteroviruses (EV). Here, we described features of children with severe HFMD caused by EV-A71 or coxsackievirus A16 (CV-A16) in Shanghai, China.

Methods: Severe EV-A71 or CV-A16 caused HFMD children admitted to the Xinhua Hospital from January 2014 and December 2016, were recruited retrospectively to the study. Read More

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http://dx.doi.org/10.1186/s12879-019-3878-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438032PMC
March 2019
1 Read

A case report of disseminated histoplasmosis and concurrent cryptococcal meningitis in a patient treated with ruxolitinib.

BMC Infect Dis 2019 Mar 27;19(1):287. Epub 2019 Mar 27.

Division of Infectious Diseases, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0711, USA.

Background: Ruxolitinib is a highly potent janus kinase inhibitor that places its users at risk for various bacterial infections and viral reactivation. However new reports are also emerging that suggest greater immunosuppression and risk for fungal disease.

Case Presentation: We report the case of a 51 year-old veteran from Guam, treated with ruxolitinib for polycythemia vera, who developed disseminated histoplasmosis and concurrent cryptococcal meningitis. Read More

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http://dx.doi.org/10.1186/s12879-019-3922-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437885PMC
March 2019
1 Read

A cross-sectional study of enteric fever among febrile patients at Ambo hospital: prevalence, risk factors, comparison of Widal test and stool culture and antimicrobials susceptibility pattern of isolates.

BMC Infect Dis 2019 Mar 27;19(1):288. Epub 2019 Mar 27.

Department of Veterinary Laboratory Technology, Ambo University, College of Agriculture and Veterinary Sciences, P.O. Box 19, Ambo, Ethiopia.

Background: Enteric fever is one of the common infectious diseases of humans. The objectives of this study were to:1) estimate the prevalence of enteric fever among febrile patients visiting Ambo hospital; 2) comparison of Widal test and stool culture;3) evaluation of the antimicrobial susceptibility of isolates; and 4) assess potential risk factors to acquire enteric fever infection.

Methods: Blood and stool samples were collected from 372 febrile patients with symptoms clinically similar to enteric fever. Read More

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
Publisher Site
http://dx.doi.org/10.1186/s12879-019-3917-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437987PMC
March 2019
5 Reads

Incidence and predictors of major adverse drug events among drug-resistant tuberculosis patients on second-line anti-tuberculosis treatment in Amhara regional state public hospitals; Ethiopia: a retrospective cohort study.

BMC Infect Dis 2019 Mar 27;19(1):286. Epub 2019 Mar 27.

Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health sciences, University of Gondar, Gondar, Ethiopia.

Background: Second line anti-tuberculosis drugs are substantially complex, long term, more costly, and more toxic than first line anti-tuberculosis drugs. In Ethiopia, evidence on the incidence and predictors of adverse drug events has been limited. Thus, this study aimed at assessing incidence and predictors of major adverse drug events among drug resistant tuberculosis patients on second line tuberculosis treatment in Amhara Regional State public hospitals, Ethiopia. Read More

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http://dx.doi.org/10.1186/s12879-019-3919-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437856PMC

Correction to: Identifying high risk subgroups of MSM: a latent class analysis using two samples.

BMC Infect Dis 2019 Mar 26;19(1):284. Epub 2019 Mar 26.

Division of Infectious Diseases, University of North Carolina at Chapel Hill, 130 Mason Farm Road, 2nd Floor, Chapel Hill, NC, 27599, USA.

Following publication of the original article [1], the author reported his family name has been marked as the first name. His given name is M. Kumi and his family name is Smith. Read More

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http://dx.doi.org/10.1186/s12879-019-3886-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434628PMC

Missed opportunities of HIV pre-exposure prophylaxis in France: a retrospective analysis in the French DAT'AIDS cohort.

BMC Infect Dis 2019 Mar 25;19(1):278. Epub 2019 Mar 25.

APHM Hôpital Sainte-Marguerite, Service d'Immuno-hématologie clinique, Aix-Marseille University, Marseille, France.

Background: HIV pre-exposure prophylaxis (PrEP) was implemented in France in November 2015 based on individual-level risk factors for HIV infection. We evaluated the proportion of missed opportunities for PrEP among newly HIV-diagnosed people entering the Dat'AIDS cohort in 2016.

Methods: Multicenter retrospective analysis in 15 French HIV clinical centers of patients with a new diagnosis of HIV infection. Read More

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http://dx.doi.org/10.1186/s12879-019-3915-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434788PMC
March 2019
2 Reads

Ten years of external quality assessment (EQA) of Neisseria gonorrhoeae antimicrobial susceptibility testing in Europe elucidate high reliability of data.

BMC Infect Dis 2019 Mar 25;19(1):281. Epub 2019 Mar 25.

WHO Collaborating Centre for Gonorrhoea and other STIs, Örebro University, Örebro, Sweden.

Background: Confidence in any diagnostic and antimicrobial susceptibility testing data is provided by appropriate and regular quality assurance (QA) procedures. In Europe, the European Gonococcal Antimicrobial Susceptibility Programme (Euro-GASP) has been monitoring the antimicrobial susceptibility in Neisseria gonorrhoeae since 2004. Euro-GASP includes an external quality assessment (EQA) scheme as an essential component for a quality-assured laboratory-based surveillance programme. Read More

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http://dx.doi.org/10.1186/s12879-019-3900-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434634PMC
March 2019
1 Read
2.613 Impact Factor