2,378 results match your criteria BMC Gastroenterology[Journal]


The impact of overlapping functional dyspepsia, belching disorders and functional heartburn on anxiety, depression and quality of life of Chinese patients with irritable bowel syndrome.

BMC Gastroenterol 2020 Jul 6;20(1):209. Epub 2020 Jul 6.

Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, No. 95 Yongan Road, Beijing, 100050, China.

Background: Functional dyspepsia (FD), belching disorders (BD) and functional heartburn (FH) are the three most common upper functional gastrointestinal disorders (FGID) in IBS patients. FD is known to exert deleterious effects on health-related quality of life (HRQoL) and the psychological status of IBS patients; however, the impact of overlapping BD and FH on anxiety, depression and HRQoL of IBS patients remains unknown. This cross-sectional study was conducted to investigate the impact of overlapping FD, BD and FH on anxiety, depression and HRQoL in patients with IBS. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01357-1DOI Listing

Human translatability of the GAN diet-induced obese mouse model of non-alcoholic steatohepatitis.

BMC Gastroenterol 2020 Jul 6;20(1):210. Epub 2020 Jul 6.

Gubra, DK-2970, Hørsholm, Denmark.

Background: Animal models of non-alcoholic steatohepatitis (NASH) are important tools in preclinical research and drug discovery. Gubra-Amylin NASH (GAN) diet-induced obese (DIO) mice represent a model of fibrosing NASH. The present study directly assessed the clinical translatability of the model by head-to-head comparison of liver biopsy histological and transcriptome changes in GAN DIO-NASH mouse and human NASH patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01356-2DOI Listing

Outcomes of liver-kidney transplantation in patients with primary hyperoxaluria: an analysis of the scientific registry of transplant recipients database.

BMC Gastroenterol 2020 Jul 3;20(1):208. Epub 2020 Jul 3.

Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health Key Laboratory of Organ Transplantation, Zhejiang University, No.79 Qingchun Road, Hangzhou, 310003, Zhejiang Province, China.

Background: Primary hyperoxaluria (PH) is an inherited disease lacking of hepatic oxalic acid metabolic enzymes which could lead to irreverisible renal damage. Currently, liver-kidney transplantation is a curative but highly invasive therapy used to treat patients with PH. However, limited studies have focused on combined liver-kidney transplantation (CLKT) and sequential liver and kidney transplantation (SLKT) in patients with PH. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01349-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333252PMC

Correction to: Comparison of the effects of adjuvant concurrent chemoradiotherapy and chemotherapy for resected biliary tract cancer.

BMC Gastroenterol 2020 Jul 2;20(1):207. Epub 2020 Jul 2.

Division of Hematology and Oncology, Department of Internal Medicine, Keimyung University, Dongsan Medical Center, 56 Dalseong-ro, Jung-gu, Daegu, 41931, South Korea.

An amendment to this paper has been published and can be accessed via the original article. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01347-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331170PMC

Increased incidence of metachronous gastric neoplasm after endoscopic resection in patients with synchronous gastric neoplasm.

BMC Gastroenterol 2020 Jun 30;20(1):206. Epub 2020 Jun 30.

Division of Gastroenterology & Hepatology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-GU, Seoul, 137-701, South Korea.

Background: Recurrence risk is a major concern after endoscopic resection (ER) of gastric neoplasms. This study was to compare metachronous risk in patients with and without synchronous neoplasms after complete ER.

Methods: After ER for gastric neoplasms, patients were divided into those with and without synchronous neoplasm. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01358-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325240PMC

Transarterial chemoembolization combined with iodine 125 seeds versus transarterial chemoembolization combined with radiofrequency ablation in the treatment of early- and intermediate-stage hepatocellular carcinoma.

BMC Gastroenterol 2020 Jun 29;20(1):205. Epub 2020 Jun 29.

Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.

Background: Transarterial chemoembolization (TACE), radiofrequency ablation (RFA), and iodine 125 seeds implantation are optional treatments for hepatocellular carcinoma (HCC). The aim of this study is to compare the efficacy of the combined treatment of TACE with iodine 125 seeds implantation (TACE-iodine 125) with TACE with RFA (TACE-RFA) in patients with early- and intermediate-stage HCC.

Methods: The study included 112 patients who were diagnosed with early- and intermediate-stage HCC from January 1, 2014, to May 31, 2018. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01355-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324959PMC

Evaluation of breath, plasma, and urinary markers of lactose malabsorption to diagnose lactase non-persistence following lactose or milk ingestion.

BMC Gastroenterol 2020 Jun 29;20(1):204. Epub 2020 Jun 29.

The Liggins Institute, The University of Auckland, Auckland, New Zealand.

Background: Adult lactase non-persistence (LNP) is due to low lactase expression, resulting in lactose malabsorption (LM). LNP is a genetic trait, but is typically determined by LM markers including breath H, blood glucose, and urinary galactose after a lactose tolerance test. Known validity of these markers using milk is limited, despite being common practice. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01352-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325051PMC

Undifferentiated carcinoma with osteoclast-like giant cells of the pancreas harboring KRAS and BRCA mutations: case report and whole exome sequencing analysis.

BMC Gastroenterol 2020 Jun 26;20(1):202. Epub 2020 Jun 26.

Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/ Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.

Background: Undifferentiated carcinoma with osteoclast-like giant cells (UC-OGC) is an extremely uncommon pancreatic neoplasm that comprises less than 1% of all exocrine pancreatic tumors. To date, cases and data from whole-exome sequencing (WES) analysis have been reported by specific studies. We report a case of pancreatic UC-OGC with a literature review, and provide novel insights into the molecular characteristics of this tumor entity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01351-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318525PMC

Relationship between mucosal healing by tacrolimus and relapse of refractory ulcerative colitis: a retrospective study.

BMC Gastroenterol 2020 Jun 26;20(1):203. Epub 2020 Jun 26.

Department of Gastroenterology, Tokyo Women's Medical University, Kawada-cho 8-1 Shinjuku-ku, Tokyo, 162-8666, Japan.

Background: Tacrolimus (TAC) is a powerful remission-inducing drug for refractory ulcerative colitis (UC). However, it is unclear whether mucosal healing (MH) influences relapse after completion of TAC.We investigated whether MH is related to relapse after TAC. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01317-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320561PMC

Predictors of surgical site infection after pancreaticoduodenectomy.

BMC Gastroenterol 2020 Jun 26;20(1):201. Epub 2020 Jun 26.

Department of Surgery, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, 270 Rama VI Road, Ratchathewi, Bangkok, 10400, Thailand.

Background: Surgical site infection (SSI) is one of the most common complications after pancreaticoduodenectomy (PD). Thus, it is beneficial to preoperatively identify patients at high risk of developing SSI. The primary aim of the present study was to identify the factors associated with SSI after PD, and the secondary aim was to identify the adverse outcomes associated with the occurrence of SSI. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01350-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318744PMC

The outcomes of modified endoscopic mucosal resection and endoscopic submucosal dissection for the treatment of rectal neuroendocrine tumors and the value of endoscopic morphology classification in endoscopic resection.

BMC Gastroenterol 2020 Jun 26;20(1):200. Epub 2020 Jun 26.

Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, No. 28 Fuxing Road, Beijing, 100853, China.

Background: To compare the outcomes of modified endoscopic mucosal resection (m-EMR) and endoscopic submucosal dissection (ESD) for rectal neuroendocrine tumors (NETs) and evaluate the value of endoscopic morphology classification in endoscopic resection (ER).

Methods: Patients with rectal NET diameters less than 2 cm who were treated between April 2007 and January 2019 were enrolled. The endoscopic morphology of rectal NETs was classified based on the endoscopic views. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01340-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318520PMC

Effects of gastric sleeve surgery on the serum levels of GH, IGF-1 and IGF-binding protein 2 in healthy obese patients.

BMC Gastroenterol 2020 Jun 25;20(1):199. Epub 2020 Jun 25.

Department of Physiology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

Background: Bariatric surgery is an effective treatment for severe obesity. It also ameliorates diabetes independently of weight loss through mechanisms that are not fully understood. In this study, we investigated the levels of GH, IGF-1 and IGF-binding protein 2 (IGFBP-2) after gastric sleeve surgery in healthy obese individuals. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01309-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318424PMC

Whipple disease diagnosed by enteroscopy: first case report in Colombia of an underdiagnosed disease and literature review.

BMC Gastroenterol 2020 Jun 23;20(1):197. Epub 2020 Jun 23.

Gastroenterology and Hepatology Department, Digestive Endoscopy Section, Fundación Santa Fe de Bogotá and Universidad de los Andes Medical School, Bogotá D.C., Colombia.

Background: Whipple's disease is a rare systemic disease caused by a gram-positive bacillus called Tropheryma whipplei. First described in 1907 as an intestinal lipodystrophy with histological finding of vacuoles in the macrophages of the intestinal mucous. Usually the symptoms are localized according to the compromised organ. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01302-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310292PMC

The impact of albumin infusion on the risk of rebleeding and in-hospital mortality in cirrhotic patients admitted for acute gastrointestinal bleeding: a retrospective study of a single institute.

BMC Gastroenterol 2020 Jun 23;20(1):198. Epub 2020 Jun 23.

Department of Gastroenterology and Hepatology, West China Hospital of Sichuan University, 37# Guoxue Lane, Chengdu, 610041, Sichuan, China.

Background: To investigate the effect of albumin infusion on cirrhotic patients admitted for acute gastrointestinal bleeding.

Methods: Medical records of cirrhotic patients who admitted due to acute gastrointestinal bleeding through January 2009 to December 2018 were reviewed. Clinical data and the total amount of albumin and red blood cell used during hospitalization were recorded. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01337-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310478PMC

The comparison of capnography and epigastric auscultation to assess the accuracy of nasogastric tube placement in intensive care unit patients.

BMC Gastroenterol 2020 Jun 22;20(1):196. Epub 2020 Jun 22.

Department of Nursing, Faculty of Nursing and Midwifery, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Background: Placement of nasogastric (NG) tubes is a common procedure for patients especially in intensive care units (ICUs). Thus, it is important to determine the correct placement of the tube to prevent misplacement in the airways. Accordingly, the aim of this study was to compare the epigastric auscultation and capnography in assessing the accuracy of NG tube insertion in ICU patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01353-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306926PMC

Comparison between transpancreatic sphincterotomy and needle-knife fistulotomy in difficulty biliary access, a retrospective study in Taiwan.

BMC Gastroenterol 2020 Jun 19;20(1):194. Epub 2020 Jun 19.

Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.

Background: Selective deep biliary cannulation is the first and the most important step before further biliary therapy. Transpancreatic sphincterotomy (TPS), and needle knife fistulotomy (NKF) were commonly used in patients with difficult cannulation, but few studies compare the outcome between TPS and NKF.

Methods: A total of 78 patients who met the criteria of difficult cannulation in the National Taiwan University hospital from October 2015 to October 2017 were retrospectively reviewed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01323-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304153PMC

Novel modified endoscopic mucosal resection of large GI lesions (> 20 mm) using an external additional working channel (AWC) may improve R0 resection rate: initial clinical experience.

BMC Gastroenterol 2020 Jun 19;20(1):195. Epub 2020 Jun 19.

Department of Gastroenterology and Gastrointestinal Oncology, Interdisciplinary Endoscopy, University Medical Center, Georg-August-University, 37075, Goettingen, Germany.

Background: En-bloc resection of large, flat dysplastic mucosal lesions of the luminal GI tract can be challenging. In order to improve the efficacy of resection for lesions ≥2 cm and to optimize R0 resection rates of lesions suspected of harboring high-grade dysplasia or early adenocarcinoma, a novel grasp and snare EMR technique utilizing a novel over the scope additional accessory channel, termed EMR Plus (EMR+), was developed. The aim of this pilot study is to describe the early safety and efficacy data from the first in human clinical cases. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01344-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304141PMC

The risk of rheumatoid arthritis among patients with inflammatory bowel disease: a systematic review and meta-analysis.

BMC Gastroenterol 2020 Jun 17;20(1):192. Epub 2020 Jun 17.

Department of Gastroenterology, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, 410008, Hunan Province, China.

Background: Studies have suggested that patients with inflammatory bowel disease (IBD) have an increased risk of rheumatoid arthritis (RA). However, the available data on this association are inconsistent. This meta-analysis aimed to determine the association between IBD and the risk of RA. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01339-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301504PMC

Impact of guideline awareness in public pharmacies on counseling of patients with acute or chronic constipation in a survey of pharmacy personnel.

BMC Gastroenterol 2020 Jun 17;20(1):191. Epub 2020 Jun 17.

Department of Pharmacology, Johannes Gutenberg University, Mainz, Germany.

Background: Constipation is often self-managed by patients and guidelines are available to aid healthcare professionals in the counseling of patients for self-management. Therefore, we have explored the knowledge and attitude of pharmacy personnel towards guidelines for the management of acute and functional chronic constipation and how they affects their recommendations.

Methods: An online survey was conducted among 201 pharmacists and pharmacy technicians from an existing panel. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01338-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301513PMC

Validation of a new risk score system for non-variceal upper gastrointestinal bleeding.

BMC Gastroenterol 2020 Jun 17;20(1):193. Epub 2020 Jun 17.

Division of Gastroenterology, Departmentof Internal Medicine, Chungnam National University Hospital, Chungnam National University School of Medicine, 282 Munhwa-ro, Jung-gu, Daejeon, 35015, Republic of Korea.

Background: Recently, a new international bleeding score was developed to predict 30-day hospital mortality in patients with upper gastrointestinal bleeding (UGIB). However, the efficacy of this newly developed scoring system has not been extensively investigated. We aimed to validate a new scoring system for predicting 30-day mortality in patients with non-variceal UGIB and determine whether a higher score is associated with re-bleeding, length of hospital stay, and endoscopic failure. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01346-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301517PMC

Prevalence of non Helicobacter pylori gastric Helicobacters in Iranian dyspeptic patients.

BMC Gastroenterol 2020 Jun 16;20(1):190. Epub 2020 Jun 16.

Department of Biology, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran.

Background: Non Helicobacter pylori gastric Helicobacters (NHPGHs) are associated with a range of upper gastrointestinal symptoms, histologic and endoscopic findings. For the first time in Iran, we performed a cross-sectional study in order to determine the prevalence of five species of NHPGHs in patients presenting with dyspepsia.

Methods: The participants were divided into H. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01331-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298804PMC

CO or air cholangiography reduces the risk of post-ERCP cholangitis in patients with Bismuth type IV hilar biliary obstruction.

BMC Gastroenterol 2020 Jun 15;20(1):189. Epub 2020 Jun 15.

Diagnosis and Treatment Center of Liver Cirrhosis, 302 Hospital of PLA, Beijing, China.

Background: Endoscopic biliary stenting by endoscopic retrograde cholangiopancreatography (ERCP) is the most common form of palliation for malignant hilar obstruction. However, ERCP in such cases is associated with a risk of cholangitis. The incidence of post-ERCP cholangitis is particularly high in Bismuth type IV hilar obstruction, and this risk is further increased when the contrast injected for cholangiography is not drained. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01341-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296950PMC
June 2020
2.365 Impact Factor

Nomogram based on blood lipoprotein for estimation of mortality in patients with hepatitis B virus-related acute-on-chronic liver failure.

BMC Gastroenterol 2020 Jun 15;20(1):188. Epub 2020 Jun 15.

Cell-gene Therapy Translational Medicine Research Center, Key Laboratory of Liver Disease of Guangdong Province, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.

Background: Acute-on-chronic liver failure (ACLF) is a clinic syndrome with substantial high short-term mortality. It is very important to stratify patients according to prognosis to decide management strategy. This study aimed to formulate and validate a nomogram model based on blood lipoprotein for prediction of 3-month mortality in patients with hepatitis B virus (HBV)-related ACLF. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01324-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294630PMC
June 2020
2.365 Impact Factor

Short-course Rifaximin therapy efficacy and lactulose hydrogen breath test in Chinese patients with diarrhea-predominant irritable bowel syndrome.

BMC Gastroenterol 2020 Jun 12;20(1):187. Epub 2020 Jun 12.

Department of Gastroenterology and Hepatology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510080, China.

Background: Gut microbiota alterations including small intestinal bacterial overgrowth (SIBO) might play a role in pathogenesis of irritable bowel syndrome (IBS). Rifaximin could effectively and safely improve IBS symptoms. The aim of this study was to investigate the effect of rifaximin on Gastrointestinal (GI) symptoms, quality of life (QOL) and SIBO eradication in Chinese IBS-D patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01336-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291629PMC

Efficacy of serum miRNA test as a non-invasive method to diagnose nonalcoholic steatohepatitis: a systematic review and meta-analysis.

BMC Gastroenterol 2020 Jun 12;20(1):186. Epub 2020 Jun 12.

Department of Infectious Diseases, Peking University First Hospital, Beijing, China.

Background: Nonalcoholic steatohepatitis (NASH) is a key turning point during the progression of nonalcoholic fatty liver disease (NAFLD). Recent studies have shown that serum miRNA tests may be effective in the diagnosis of NAFLD. We conducted a meta-analysis to assess the evidence for the diagnostic efficacy of serum miRNAs in patients with NAFLD and its subtype, NASH, in particular. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01334-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291448PMC

Eosinophilic esophagitis (EoE); a disease that must not be neglected - implications of esophageal rupture and its management.

BMC Gastroenterol 2020 Jun 11;20(1):185. Epub 2020 Jun 11.

Durham University, Durham, United Kingdom.

Background: The prevalence of Eosinophilic esophagitis (EoE) is increasing, a severe complication of EoE is spontaneous perforation of the oesophagus. It is of great importance to be aware of this risk and handle this severe complication carefully.

Case Presentation: A middle-age man with EoE since 2004, had a total esophageal bolus obstruction while eating lunch at the local hospital. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01330-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291749PMC

A newly designed uncovered biliary stent for palliation of malignant obstruction: results of a prospective study.

BMC Gastroenterol 2020 Jun 10;20(1):184. Epub 2020 Jun 10.

Division of Gastroenterology and Hepatology, Stony Brook University Hospital, 101 Nicolls Road, HSC Building, 17th floor, Room 063, Stony Brook, New York, Stony Brook, NY, 11794, USA.

Background: Biliary decompression can reduce symptoms and improve quality of life in patients with malignant biliary obstruction. Endoscopically placed stents have become the standard of care for biliary drainage with the aim of improving hepatic function, relieving jaundice, and reducing adverse effects of obstruction. The purpose of this study was to evaluate the performance characteristics of a newly-designed, uncovered metal biliary stent for the palliation of malignant biliary obstruction. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01325-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288422PMC

Hypophosphataemia after ferric carboxymaltose is unrelated to symptoms, intestinal inflammation or vitamin D status.

BMC Gastroenterol 2020 Jun 10;20(1):183. Epub 2020 Jun 10.

Department of Gastroenterology, Northern Health, 185 Cooper St, Epping, Victoria, 3076, Australia.

Background: Intravenous iron replacement is recommended for iron-deficient patients with inflammatory bowel disease (IBD), but may be associated with hypophosphataemia, predisposing to osteomalacia and fractures. This study aimed to evaluate the incidence and risk factors for hypophosphataemia following intravenous ferric carboxymaltose (FCM) in patients with IBD.

Methods: This prospective observational study of patients with and without IBD evaluated serum phosphate for 28 days following intravenous FCM, and assessed associations with symptoms, markers of inflammation and vitamin D status. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01298-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288415PMC

A combination of single-balloon enteroscopy-assisted laparoscopy and endoscopic mucosal resection for treating gastrointestinal venous malformations in blue rubber bleb nevus syndrome: a case report.

BMC Gastroenterol 2020 Jun 10;20(1):182. Epub 2020 Jun 10.

Department of Gastroenterology, Yinzhou Hospital affiliated to Medical School of Ningbo University, 251 Baizhang Rd. Ningbo, Zhejiang, 315040, China.

Background: Blue rubber bleb nevus syndrome (BRBNS) is a rare congenital disease characterized by multifocal venous malformations. It remains a considerable challenge in treating the gastrointestinal (GI) venous malformations due to multiple lesions throughout the GI tract, and the likelihood of recurrence. We report a case study of BRBNS in the GI tract, in which GI venous malformations and related GI bleeding were successfully treated with a combination of multiple endoscopic procedures. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01328-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285593PMC
June 2020
2.365 Impact Factor

Risk of rebleeding from gastroesophageal varices after initial treatment with cyanoacrylate; a systematic review and pooled analysis.

BMC Gastroenterol 2020 Jun 9;20(1):181. Epub 2020 Jun 9.

Department of Gastroenterology, The Third Xiangya Hospital of Central South University, Changsha city, Hunan, P.R. China.

Background: Cyanoacrylate alone or in combination with other interventions, can be used to achieve variable rates of success in preventing rebleeding. Our study aims to assess the pooled risk of gastric and esophageal varices rebleeding after an initial treatment with cyanoacrylate alone and/or in combination with other treatments, by a systematic review of the literature and pooled analysis.

Methods: PubMed, EMBASE, SCOPUS, and the Cochrane library were searched for studies that reported the risk of rebleeding during the follow-up period after treatment of gastric or esophageal varices with either cyanoacrylate alone or in combination with other treatments. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01333-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285616PMC
June 2020
2.365 Impact Factor

Value of routine test for identifying colorectal cancer from patients with nonalcoholic fatty liver disease.

BMC Gastroenterol 2020 Jun 9;20(1):180. Epub 2020 Jun 9.

Institute of Information Security and Big Data, Central South University, 932 South Lushan Rd, Changsha, Hunan, 410083, P.R. China.

Background: Nonalcoholic fatty liver disease (NAFLD) is a risk factor for colorectal neoplasms. Our goal is to explore the relationship between NAFLD and colorectal cancer (CRC) and to analyze potential indicators for screening CRC in NAFLD based on clinical big data.

Methods: Demographic information and routine clinical indicators were extracted from Xiangya Medical Big Data Platform. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01327-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285775PMC

Optimization of impedance-measured reflux events in GORD utilizing acid exposure time.

BMC Gastroenterol 2020 Jun 9;20(1):179. Epub 2020 Jun 9.

Gastroenterology and Liver Center, Greenville Health System, Greenville, SC, USA.

Background: Combining impedance with pH monitoring improves the detection and characterization of gastro-oesophageal reflux (GOR), yet the two modalities frequently differ in GOR quantification. Ambulatory 24-h pH-impedance monitoring often reveals more significant oesophageal acid exposure than impedance-measured reflux activity in patients with symptomatic gastro-oesophageal reflux disease (GORD). The purpose of this study is to elucidate the discrepancies between these modalities by assessing the predictive accuracy of impedance compared to acid exposure standards. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01321-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281954PMC

Non-steroidal anti-inflammatory drug-induced enteropathy as a major risk factor for small bowel bleeding: a retrospective study.

BMC Gastroenterol 2020 Jun 8;20(1):178. Epub 2020 Jun 8.

Department of Internal Medicine, Kosin University College of Medicine, Kosin University Gospel Hospital, Busan, South Korea.

Background: Small bowel (SB) bleeding accounts for 5% of all gastrointestinal (GI) bleeding cases and 80% of obscure GI bleeding cases. Although angioectasia is the common etiology of SB bleeding, nonsteroidal anti-inflammatory drug (NSAID)-induced SB lesions are also reported as a major cause in studies from Eastern countries. Herein, we assessed the frequency of occurrence of NSAID-induced SB lesions in Korean patients with obscure GI bleeding. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01329-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282042PMC
June 2020
2.365 Impact Factor

Indications and diagnostic yield of small-bowel capsule endoscopy in a real-world setting.

BMC Gastroenterol 2020 Jun 8;20(1):177. Epub 2020 Jun 8.

Digestive Disease Center, Bispebjerg Hospital, University of Copenhagen, Bispebjerg Bakke 23, DK-2400, Copenhagen NV, Denmark.

Background: Indications and diagnostic yield of small-bowel video capsule endoscopy (SB-VCE) are communicated in recent clinical academic guidelines. However, guidelines are based mainly on relatively few, small, selection-biased studies at experienced centers, and thus we lack information on indications and diagnostic yield of SB-VCE in the real-world community setting. The aim of the study was to evaluate indications and diagnostic yield of SB-VCE in the real-world community setting. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01326-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282185PMC

Use of Immunostaining for the diagnosis of Lymphovascular invasion in superficial Barrett's esophageal adenocarcinoma.

BMC Gastroenterol 2020 Jun 5;20(1):175. Epub 2020 Jun 5.

Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.

Background: The prevalence of Barrett's esophageal adenocarcinoma (BEA) is increasing in Japan. Accurate assessment of lymphovascular invasion (LVI) after endoscopic resection or surgery is essential in evaluating treatment response. This study aimed to assess the usefulness of immunostaining in determining the extent of LVI in superficial BEA. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01319-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275380PMC

Portal hypertension as a result of the incomplete surgically treated advanced alveolar echinococcosis: a case description.

BMC Gastroenterol 2020 Jun 5;20(1):176. Epub 2020 Jun 5.

Department and Clinic of Tropical and Parasitic Diseases, Poznan University of Medical Sciences, Przybyszewskiego Street 49, 60-355, Poznań, Poland.

Background: Infection of Echinococcus multilocularis causes in humans the alveolar echinococcosis. Although the infection has world-wide distribution it is rarely detected. Diagnosis of alveococcosis is difficult because of not typical clinical picture and irregular results of radiological examinations suggesting neoplasmatic process which begins in the liver tissue or in the biliary tracts. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01320-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275433PMC

Aetiologies and outcomes of patients with abdominal pain presenting to an emergency department of a tertiary hospital in Tanzania: a prospective cohort study.

BMC Gastroenterol 2020 Jun 5;20(1):173. Epub 2020 Jun 5.

Emergency Medicine Department, Muhimbili National Hospital, Dar es Salaam, Tanzania.

Background: Abdominal pain in adults represents a wide range of illnesses, often warranting immediate intervention. This study is to fill the gap in the knowledge about incidence, presentation, causes and mortality from abdominal pain in an established emergency department of a tertiary hospital in Tanzania.

Methods: This was a prospective cohort study of adult (age ≥ 18 years) patients presenting to the Emergency Medicine Department of Muhimbili National Hospital (EMD-MNH) in Dar Es Salaam, Tanzania with non-traumatic abdominal pain from September 2017 to October 2017. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01313-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275297PMC

Hemorrhagic cholecystitis with rare imaging presentation: a case report and a lesson learned from neglected medication history of NSAIDs.

BMC Gastroenterol 2020 Jun 5;20(1):172. Epub 2020 Jun 5.

Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University School of Medicine, 79 Qingchun Road, Hangzhou, 310003, China.

Background: Gallbladder carcinogenesis, frequently occurredin chronic cholecystitis patients, requires radical resection. We herein describe a hemorrhagic cholecystitis case that failed to be differentiated from gallbladder cancer preoperatively owing to the neglected medication history of long term oral nonsteroidal anti-inflammatory drugs (NSIADs) intake.

Case Presentation: A 57-year-old Chinese female was admitted for right upper quadrant pain with the initial diagnosis of cholecystitis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01312-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275556PMC

Identification of novel alternative splicing isoform biomarkers and their association with overall survival in colorectal cancer.

BMC Gastroenterol 2020 Jun 5;20(1):171. Epub 2020 Jun 5.

Tianjia Genomes Tech CO., LTD., Anhui Chaohu Economic Develop Zone, No. 6 Longquan Road, Hefei, 238014, People's Republic of China.

Background: Alternative splicing (AS) is an important mechanism of regulating eukaryotic gene expression. Understanding the most common AS events in colorectal cancer (CRC) will help developing diagnostic, prognostic or therapeutic tools in CRC.

Methods: Publicly available RNA-seq data of 28 pairs of CRC and normal tissues and 18 pairs of metastatic and normal tissues were used to identify AS events using PSI and DEXSeq methods. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01288-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275609PMC
June 2020
2.365 Impact Factor

Inflammatory polyps occur more frequently in inflammatory bowel disease than other colitis patients.

BMC Gastroenterol 2020 Jun 5;20(1):170. Epub 2020 Jun 5.

Gastroenterology division, Stanford University, School of Medicine, Palo Alto, California, USA.

Background: Colitis is generally considered a risk factor for colon neoplasia. However, not all types of colitis seem to have equal neoplastic transformation potential.

Aim: To determine the prevalence of colorectal polyps in a predominantly African American population with inflammatory bowel disease (IBD) and Non-IBD/Non-Infectious Colitis (NIC). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01279-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275388PMC

Percutaneous stent placement for malignant hilar biliary obstruction: side-by-side versus stent-in-stent technique.

BMC Gastroenterol 2020 Jun 5;20(1):174. Epub 2020 Jun 5.

Department of Interventional Radiology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Gulou District, Nanjing, 210029, China.

Background: Currently, side-by-side (SBS) and stent-in-stent (SIS) are the two main techniques for stent deployment to treat hilar biliary obstructions. Previous studies comparing these two techniques are very limited, and thus, no consensus has been reached on which technique is better. The purpose of this study is to compare the clinical efficacy and safety of SBS and SIS deployment via a percutaneous approach for malignant hilar biliary obstruction. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01316-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275544PMC

The influence of demographic characteristics on constipation symptoms: a detailed overview.

BMC Gastroenterol 2020 Jun 3;20(1):168. Epub 2020 Jun 3.

Department of Surgery, Anorectal Physiology Laboratory, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30 001, 9700, RB, Groningen, the Netherlands.

Background: Diagnosing constipation remains difficult and its treatment continues to be ineffective. The reason may be that the symptom patterns of constipation differ in different demographic groups. We aimed to determine the pattern of constipation symptoms in different demographic groups and to define the symptoms that best indicate constipation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01306-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268616PMC

Liver cirrhosis in a patient with hepatic hereditary hemorrhagic telangiectasia and Budd-Chiari syndrome: a case report.

BMC Gastroenterol 2020 Jun 3;20(1):169. Epub 2020 Jun 3.

Department of Hepatology and Gastroenterology, the Third Central Clinical College of Tianjin Medical Universityssss, 83 Jintang Road, Hedong District, Tianjin, 300170, China.

Background: Hereditary hemorrhagic telangiectasia (HHT) often involves the liver, and belongs to abnormal blood vessel disease. The etiology of Budd-Chiari syndrome (BCS) is not clear, but congenital vascular dysplasia is considered to be one of the causes. Liver cirrhosis due to hepatic hereditary hemorrhagic telangiectasia concomitant with BCS has not been reported. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01311-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268624PMC

Juvenile polyposis syndrome might be misdiagnosed as familial adenomatous polyposis: a case report and literature review.

BMC Gastroenterol 2020 Jun 1;20(1):167. Epub 2020 Jun 1.

Department of Colorectal Surgery, Changhai Hospital, 168 Changhai Road, Shanghai, 200433, China.

Background: Juvenile polyposis syndrome (JPS) is a rare disorder characterized by the presence of multiple juvenile polyps in the gastrointestinal tract, and germline mutations in SMAD4 or BMPR1A. Due to its rarity and complex clinical manifestation, misdiagnosis often occurs in clinical practice.

Case Presentation: A 42-year-old man with multiple pedunculated colorectal polyps and concomitant rectal adenocarcinoma was admitted to our hospital. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01238-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268223PMC
June 2020
2.365 Impact Factor

Evaluation of four scoring systems in prognostication of acute pancreatitis for elderly patients.

BMC Gastroenterol 2020 Jun 1;20(1):165. Epub 2020 Jun 1.

Geriatrics Department, Zhongda Hospital Southeast University, No.87, Dingjiaqiao, Nanjing, China.

Background: To evaluate the ability of four scoring systems (Ranson, BISAP, Glasgow, and APACHE II) to predict outcomes of acute pancreatitis (AP) in elderly patients.

Methods: This was a retrospective study of 918 patients presenting with AP at Zhongda Hospital Southeast University, from January 2015 to December 2018. We divided patients into two groups: 368 patients who were ≥ 60 years old, and 550 patients who were < 60 years old. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01318-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268671PMC

The development of early ascites is associated with shorter overall survival in patients with hepatocellular carcinoma treated with drug-eluting embolic chemoembolization.

BMC Gastroenterol 2020 Jun 1;20(1):166. Epub 2020 Jun 1.

Liver Unit, Hospital Universitario Central de Asturias, 33011, Oviedo, Spain.

Background: A single-centre cohort study was performed to identify the independent factors associated with the overall survival (OS) of hepatocellular carcinoma (HCC) patients treated with transarterial chemoembolization with drug-eluting beads (DEB-TACE).

Methods: A total of 216 HCC patients who underwent DEB-TACE from October 2008 to October 2015 at a tertiary hospital were consecutively recruited. The analysis of prognostic factors associated with overall survival after DEB-TACE, stressing the role of post-TACE events, was performed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01307-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268728PMC

A case report of iatrogenic gas gangrene post colonoscopy successfully treated with conservative management- is surgery always necessary?

BMC Gastroenterol 2020 May 27;20(1):163. Epub 2020 May 27.

The Mater Hospital, Townsville, Australia.

Background: Colonoscopy is a routine procedure in diagnosis and treatment of colonic disease. While generally regarded as a safe procedure, potentially fatal complications can occur. Gas gangrene is one such complication, with very high mortality. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01314-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254699PMC

Elevated hemoglobin A1c is associated with the presence of pancreatic cysts in a high-risk pancreatic surveillance program.

BMC Gastroenterol 2020 May 27;20(1):161. Epub 2020 May 27.

Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, USA.

Background: Emerging evidence demonstrates that surveillance of individuals at high-risk (HRIs) of developing pancreatic adenocarcinoma allows for identification and treatment of resectable tumors with improved survival. Population-based data suggest that hyperglycemia may be present up to three years before the development of pancreatic cancer. We investigated whether elevated hemoglobin A1c (HbA1c) is associated with the development of pancreatic cysts in a pancreatic surveillance program. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01308-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254640PMC

High-density lipoprotein cholesterol to low-density lipoprotein cholesterol ratio in early assessment of disease severity and outcome in patients with acute pancreatitis admitted to the ICU.

BMC Gastroenterol 2020 May 27;20(1):164. Epub 2020 May 27.

Department of Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China.

Background: Patients with acute pancreatitis usually exhibit dyslipidemia and oxidative stress. However, the significance of high-density lipoprotein cholesterol (HDL-C) level, low-density lipoprotein cholesterol (LDL-C) level and the HDL-C/LDL-C ratio (H/L ratio) as markers for disease progression remain unknown.

Aim: The aim of this study was to evaluate the role of HDL-C levels, LDL-C levels and the H/L ratio as markers of disease progression in patients admitted to the intensive cate unit with acute pancreatitis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01315-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254649PMC

Stretta radiofrequency treatment vs Toupet fundoplication for gastroesophageal reflux disease: a comparative study.

BMC Gastroenterol 2020 May 27;20(1):162. Epub 2020 May 27.

Department of General Surgery, the Second Hospital of Hebei Medical University, 19 Jiuzhong Street, Shijiazhuang, 050000, China.

Background: Outcomes of gastroesophageal reflux disease (GERD) using Toupet fundoplication (TF) and Stretta radiofrequency (SRF) have not been compared and this study was conducted to compare therapeutic efficacy of the two methods.

Methods: This retrospective study analyzed a total of 230 patients undergoing TF or SRF at our hospital. Baseline data, reflux symptoms, the DeMeester scores, lower esophageal sphincter (LES) pressure and adverse events were compared over 1 year period. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01310-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251847PMC