Statin therapy in critical illness: an international survey of intensive care physicians' opinions, attitudes and practice.
- Manu Shankar-Hari,
- Peter S Kruger,
- Stefania Di Gangi,
- Damon C Scales,
- Gavin D Perkins,
- Danny F McAuley,
- Marius Terblanche
BMC Clin Pharmacol 2012 Jun 28;12:13. Epub 2012 Jun 28.
Division of Asthma, Allergy and Lung Biology, King's College London, London, UK.
Background: Pleotropic effects of statins on inflammation are hypothesised to attenuate the severity of and possibly prevent the occurrence of the host inflammatory response to pathogen and infection-related acute organ failure. We conducted an international survey of intensive care physicians in Australia, New Zealand (ANZ) and United Kingdom (UK). The aims of the survey were to assess the current prescribing practice patterns, attitudes towards prescribing statin therapy in critically ill patients and opinions on the need for an interventional trial of statin therapy in critically ill patients. Read More