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    1576 results match your criteria BMC Cardiovascular Disorders[Journal]

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    Long-term prognosis of patients with non-ST-segment elevation myocardial infarction according to coronary arteries atherosclerosis extent on coronary angiography: a historical cohort study.
    BMC Cardiovasc Disord 2017 Nov 16;17(1):279. Epub 2017 Nov 16.
    Department of Health, Science and Technology, Aalborg University, Aalborg, Denmark.
    Background: Patients with non-ST-segment elevation myocardial infarction (NSTEMI) without obstructive coronary artery disease (CAD) are often managed differently than those with obstructive CAD, therefore we aimed in this study to examine the long-term prognosis of patients with NSTEMI according to the degree of CAD on coronary angiography (CAG).

    Methods: We examined 8.889 consecutive patients admitted for first time NSTEMI during 2000-2011, to whom CAG was performed. Read More

    Elevated exhaled acetone concentration in stage C heart failure patients with diabetes mellitus.
    BMC Cardiovasc Disord 2017 Nov 16;17(1):280. Epub 2017 Nov 16.
    Department of Cardiovascular Medicine, Fukushima Medical University, 1 Hikarigaoka, Fukushima, Fukushima, 960-1295, Japan.
    Background: Breath acetone is a noninvasive biomarker of heart failure; however, its significance in heart failure patients with diabetes mellitus has yet to be clarified. The objective of this study is to investigate whether exhaled acetone concentration is a noninvasive biomarker in heart failure patients with diabetes mellitus.

    Methods: This study prospectively included 35 diabetic patients with stage C heart failure and 20 diabetic patients with or at risk of heart failure (stage A or B). Read More

    Effects of angiotensin receptor blockers on neointimal characteristics in angina patients requiring stent implantation: optical coherence tomography analysis.
    BMC Cardiovasc Disord 2017 Nov 15;17(1):278. Epub 2017 Nov 15.
    Department of Cardiology, Korea University Anam Hospital, Inchon-ro 73, Seongbuk-gu, Seoul, South Korea.
    Background: Angiotensin receptor blockers (ARBs) are known for its anti-inflammatory and anti-proliferative effects. The aim of the study was to evaluate long-term effects of ARBs on morphologic characteristics of stent restenosis in patients with coronary artery disease requiring stent implantation by optical coherence tomography (OCT).

    Methods: Patients with coronary artery disease having history of drug-eluting stent implantation (n = 407) were analyzed on the basis of ARB therapy as the ARB group (n = 162) and the non-ARB group (n = 245). Read More

    Case report: electrical storm during induced hypothermia in a patient with early repolarization.
    BMC Cardiovasc Disord 2017 Nov 15;17(1):277. Epub 2017 Nov 15.
    Cardiovascular Research Institute Basel (CRIB), University Hospital Basel, Basel, Switzerland.
    Background: Population based studies showed an association of early repolarization in the electrocardiogram (ECG) and a higher rate of sudden cardiac death presumably due to ventricular fibrillation. The triggers for ventricular fibrillation in patients with early repolarization are not fully understood.

    Case Presentation: We describe the case of a young patient with a survived ventricular fibrillation arrest while asleep followed by multiple episodes of recurrent ventricular fibrillation. Read More

    Control of cardiovascular risk factors and its determinants in the general population- findings from the STAAB cohort study.
    BMC Cardiovasc Disord 2017 Nov 2;17(1):276. Epub 2017 Nov 2.
    Institute of Clinical Epidemiology and Biometry, University of Würzburg, Würzburg, Germany.
    Background: While data from primary care suggest an insufficient control of vascular risk factors, little is known about vascular risk factor control in the general population. We therefore aimed to investigate the adoption of adequate risk factor control and its determinants in the general population free of cardiovascular disease (CVD).

    Methods: Data from the Characteristics and Course of Heart Failure Stages A-B and Determinants of Progression (STAAB) Cohort Study, a population-based study of inhabitants aged 30 to 79 years from the general population of Würzburg (Germany), were used. Read More

    Predicting operative mortality in octogenarians for isolated coronary artery bypass grafting surgery: a retrospective study.
    BMC Cardiovasc Disord 2017 Nov 2;17(1):275. Epub 2017 Nov 2.
    Division of Cardiac Surgery, Department of Surgery, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada.
    Background: Available cardiac surgery risk scores have not been validated in octogenarians. Our objective was to compare the predictive ability of the Society of Thoracic Surgeons (STS) score, EuroSCORE I, and EuroSCORE II in elderly patients undergoing isolated coronary artery bypass grafting surgery (CABG).

    Methods: All patients who underwent isolated CABG (2002 - 2008) were identified from the Alberta Provincial Project for Outcomes Assessment in Coronary Heart Disease (APPROACH) registry. Read More

    Vitamin D3 repletion versus placebo as adjunctive treatment of heart failure patient quality of life and hormonal indices: a randomized, double-blind, placebo-controlled trial.
    BMC Cardiovasc Disord 2017 Oct 30;17(1):274. Epub 2017 Oct 30.
    Providence Saint Patrick Hospital, 500 W. Broadway St, Missoula, MT, 59802, USA.
    Background: Vitamin D status may influence heart failure (HF) patient outcomes by affecting b-type natriuretic peptide (BNP), parathyroid hormone (PTH), and enhancing cardiac contractility. Vitamin D deficiency is associated with morbidity and mortality in HF patients. The objective of this study was to determine if vitamin D3 at a comparatively high dose would replete 25-hydroxyvitamin D (25(OH)D) stores, improve BNP, PTH, cardiopulmonary function, reduce inflammatory markers, and improve quality of life (QOL) in HF patients. Read More

    Fluid upstream shear stress of rabbit aortic stenosis inhibits neointimal hyperplasia by promoting endothelization after balloon injury.
    BMC Cardiovasc Disord 2017 Oct 30;17(1):273. Epub 2017 Oct 30.
    Department of Cardiology, Jiangmen Central Hospital, No.23, Haibang Street, Jiangmen, Guangdong, 529030, China.
    Background: Atherosclerosis is associated with disturbed blood flow characterized by low and oscillatory shear stress (SS), however, few study directly links SS to neointimal hyperplasia in animal model. This study was focused on the effects of changed SS upon the neointimal hyperplasia which responded to balloon injury in a novel rabbit model with partially-constricted abdominal aorta.

    Methods: We established a rabbit model subjected to partial abdominal aortic constriction with a cylinder-shaped cannula as a model of disturbed flow, which was similar to the hemodynamic features of stenosis caused by atherosclerosis plaque. Read More

    The protective effect of activating Nrf2 / HO-1 signaling pathway on cardiomyocyte apoptosis after coronary microembolization in rats.
    BMC Cardiovasc Disord 2017 Oct 24;17(1):272. Epub 2017 Oct 24.
    Department of Cardiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, 530021, China.
    Background: Myocardial apoptosis is closely related to myocardial injury caused by coronary microembolization (CME).Nuclear factor erythroid 2-like (Nrf2) has been taken into account as an inhibitor of apoptosis in various tissues. Thus, this research aims to investigate which part Nrf2/HO-1 signaling pathway plays in myocardial apoptosis process following the effect of CME on rats. Read More

    Ideal cardiovascular health and the subclinical impairments of cardiovascular diseases: a cross-sectional study in central south China.
    BMC Cardiovasc Disord 2017 Oct 18;17(1):269. Epub 2017 Oct 18.
    Department of Health Management Centre, the Third Xiangya Hospital, Central South University, Tongzipo Road 138, Changsha, Hunan Province, 410013, China.
    Background: Ideal cardiovascular health (CVH) is related to a low cardiovascular disease risk profile. This study aimed to investigate CVH metrics with both the biomarkers and markers of subclinical impairments of cardiovascular diseases (CVDs) in subjects from central south China.

    Methods: The ideal CVH score (non-smoking status; ideal body mass index; regular physical activity; healthy diet; and an optimal serum cholesterol, blood pressure, and glucose profile; 1 point for each; total score: 0-7) was collected from 3009 participants without a history of CVDs. Read More

    Comparison of circulating dendritic cell and monocyte subsets at different stages of atherosclerosis: insights from optical coherence tomography.
    BMC Cardiovasc Disord 2017 Oct 18;17(1):270. Epub 2017 Oct 18.
    Department of Cardiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
    Background: While specific patterns of circulating dendritic cells (DCs) and monocytes are associated with the incidence of coronary artery disease, the characterization of circulating DC and monocyte subsets in patients with different stages of atherosclerosis remains unclear.

    Methods: Forty-eight patients with unstable angina pectoris (UAP) diagnosed by angiography were enrolled. Likewise, 31 patients with ST-segment elevation myocardial infarction (STEMI) were enrolled and confirmed with the presence of thrombosis by angiography. Read More

    Deletion of the NR4A nuclear receptor NOR1 in hematopoietic stem cells reduces inflammation but not abdominal aortic aneurysm formation.
    BMC Cardiovasc Disord 2017 Oct 18;17(1):271. Epub 2017 Oct 18.
    Department of Medicine, Division of Cardiology, Pittsburgh Heart, Lung, Blood, and Vascular Medicine Institute, UPMC and University of Pittsburgh School of Medicine, Pittsburgh, PA, 15261, USA.
    Background: The NR4A3 orphan nuclear hormone receptor, NOR1, functions as a constitutively active transcription factor to regulate inflammation, proliferation, and cell survival during pathological vascular remodeling. Inflammatory processes represent key mechanisms leading to abdominal aortic aneurysm (AAA) formation. However, a role of NOR1 in AAA formation has not been investigated previously. Read More

    Detrimental effects of specific Periodontopathic bacterial infection on tachyarrhythmia compared to Bradyarrhythmia.
    BMC Cardiovasc Disord 2017 Oct 17;17(1):267. Epub 2017 Oct 17.
    Department of Cardiovascular Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8549, Japan.
    Background: Tachyarrhythmia (TA) and bradyarrhythmia (BA) are cardiac rhythm disorders that result in the decline of quality of life. While patients with periodontitis are at a high risk of cardiovascular disease (CVD), little causal information between TA and BA has been provided to date. To assess the relationship, periodontal bacterial infection in patients with TA or BA was evaluated. Read More

    Quality of life questionnaire predicts poor exercise capacity only in HFpEF and not in HFrEF.
    BMC Cardiovasc Disord 2017 Oct 17;17(1):268. Epub 2017 Oct 17.
    Clinic of Cardiology, University Clinical Centre of Kosova, Rrethi i Spitalit, P.N, 10000, Prishtina, Kosovo.
    Background: The Minnesota Living with Heart Failure Questionnaire (MLHFQ) is the most widely used measure of quality of life (QoL) in HF patients. This prospective study aimed to assess the relationship between QoL and exercise capacity in HF patients.

    Methods: The study subjects were 118 consecutive patients with chronic HF (62 ± 10 years, 57 females, in NYHA I-III). Read More

    Takotsubo cardiomyopathy in a patient with ileus: a case report.
    BMC Cardiovasc Disord 2017 Oct 17;17(1):266. Epub 2017 Oct 17.
    Department of Surgery, Madou Sin-Lau Hospital, 20 Lingzilin, Tainan, 72152, Taiwan.
    Background: Takotsubo cardiomyopathy (TCM) is a form of stress-induced cardiomyopathy featured by the dilatation of the apex of the left ventricle during systole. Whereas the pathogenesis of this disorder is not well understood, it usually occurs after an emotional or physical stress such as acute asthma, surgery, chemotherapy, and stroke. However, its occurrence in ileus patients is rarely reported. Read More

    Left ventricular non-compaction cardiomyopathy with coronary artery anomaly complicated by ventricular tachycardia.
    BMC Cardiovasc Disord 2017 Oct 16;17(1):263. Epub 2017 Oct 16.
    Centre for Research and Development, Uppsala University/Region Gävleborg, SE-801 87, Gävle, Sweden.
    Background: Non-compaction cardiomyopathy (NCCM) is characterized by prominent trabeculations, deep intertrabecular recesses, and a thick non-compacted endocardial myocardium. Prevalence in the general population remains unclear, but echocardiography series report 0.05%. Read More

    Diagnostic performance of various familial hypercholesterolaemia diagnostic criteria compared to Dutch lipid clinic criteria in an Asian population.
    BMC Cardiovasc Disord 2017 Oct 16;17(1):264. Epub 2017 Oct 16.
    Institute for Pathology, Laboratory and Forensic Medicine (I-PPerForM), University Teknologi MARA, 47000, Sungai Buloh, Selangor, Malaysia.
    Background: Familial hypercholesterolaemia (FH) is a genetic disorder with a high risk of developing premature coronary artery disease that should be diagnosed as early as possible. Several clinical diagnostic criteria for FH are available, with the Dutch Lipid Clinic Criteria (DLCC) being widely used. Information regarding diagnostic performances of the other criteria against the DLCC is scarce. Read More

    An inappropriate pacing threshold increase after repeated electrical storm in a patient with implantable cardioverter defibrillator.
    BMC Cardiovasc Disord 2017 Oct 16;17(1):265. Epub 2017 Oct 16.
    Department of Global Biostatistics and Data Science, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, 70112, USA.
    Background: Implantable cardioverter defibrillators (ICD) are capable of effectively terminating malignant ventricular arrhythmia and are the most effective way to prevent sudden cardiac death. However, some evidences demonstrated that both anti-tachycardia pacing (ATP) and ICD shock can also bring adverse prognosis.

    Case Presentation: A 66-year-old Han Chinese man with prior ICD implantation was admitted to our hospital because of frequent ICD shocks. Read More

    Effectiveness of a PRECEDE-based education intervention on quality of life in elderly patients with chronic heart failure.
    BMC Cardiovasc Disord 2017 Oct 16;17(1):262. Epub 2017 Oct 16.
    Department of Geriatrics, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
    Background: One of the most important challenges in public health is to improve the quality of life in patients with chronic heart failure (CHF). Depression, self-care capacity, and quality of life interact each other in these patients. It's difficult to treat with general education programs and conventional therapy. Read More

    Uncertainty on the effectiveness and safety of rivaroxaban in premenopausal women with atrial fibrillation: empirical evidence needed.
    BMC Cardiovasc Disord 2017 Oct 13;17(1):260. Epub 2017 Oct 13.
    Department for Health Evidence, Radboud University Medical Center, Nijmegen, The Netherlands.
    Background: Novel anticoagulations (NOACs) are increasingly prescribed for the prevention of stroke in premenopausal women with atrial fibrillation. Small studies suggest NOACs are associated with a higher risk of abnormal uterine bleeds than vitamin K antagonists (VKAs). Because there is no direct empirical evidence on the benefit/risk profile of rivaroxaban compared to VKAs in this subgroup, we synthesize available indirect evidence, estimate decision uncertainty on the treatments, and assess whether further research in premenopausal women is warranted. Read More

    Right precordial-directed electrocardiographical markers identify arrhythmogenic right ventricular cardiomyopathy in the absence of conventional depolarization or repolarization abnormalities.
    BMC Cardiovasc Disord 2017 Oct 13;17(1):261. Epub 2017 Oct 13.
    Department of Cardiology, Clinical Sciences, Lund University, Lund, Sweden.
    Background: Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) carries a risk of sudden death. We aimed to assess whether vectorcardiographic (VCG) parameters directed toward the right heart and a measured angle of the S-wave would help differentiate ARVD/C with otherwise normal electrocardiograms from controls.

    Methods: Task Force 2010 definite ARVD/C criteria were met for all patients. Read More

    Feasibility and safety of early discharge after transfemoral transcatheter aortic valve implantation - rationale and design of the FAST-TAVI registry.
    BMC Cardiovasc Disord 2017 Oct 10;17(1):259. Epub 2017 Oct 10.
    Catania Division of Cardiology, Ferrarotto Hospital, University of Catania, Via Salvatore Citelli 6, Catania, Italy.
    Background: There is an increasing trend towards shorter hospital stays after transcatheter aortic valve implantation (TAVI), in particular for patients undergoing the procedure via transfemoral (TF) access. Preliminary data suggest that there exists a population of patients that can be discharged safely very early after TF-TAVI. However, current evidence is limited to few retrospective studies, encompassing relatively small sample sizes. Read More

    Circulating adipocyte fatty acid-binding protein is a predictor of cardiovascular events in patients with stable angina undergoing percutaneous coronary intervention.
    BMC Cardiovasc Disord 2017 Oct 10;17(1):258. Epub 2017 Oct 10.
    Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Okayama, 700-8558, Japan.
    Background: Adipocyte fatty acid-binding protein (A-FABP) is expressed in both adipocytes and macrophages. Recent studies have shown that A-FABP is secreted by adipocytes and that the A-FABP concentration is associated with obesity, insulin resistance, and atherosclerosis. We have reported that the coronary atherosclerotic burden is associated with the serum A-FABP concentration. Read More

    Effect of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers on cardiovascular events in patients with heart failure: a meta-analysis of randomized controlled trials.
    BMC Cardiovasc Disord 2017 Oct 5;17(1):257. Epub 2017 Oct 5.
    Department of Cardiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 Yanchang Road, Shanghai, China.
    Background: Heart failure (HF) remains a significant cause of morbidity and mortality. Multiple trials over the past several years have examined the effects of both angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) in the treatment of left ventricular dysfunction, both acutely after myocardial infarction and in chronic heart failure. Yet, there is still confusion regarding the relative efficacy of rennin-angiotensin-aldosterone system (RAAS) inhibition. Read More

    Effect of pocket irrigation with antimicrobial on prevention of pacemaker pocket infection: a meta-analysis.
    BMC Cardiovasc Disord 2017 Sep 30;17(1):256. Epub 2017 Sep 30.
    Department of Cardiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510120, People's Republic of China.
    Background: The presence of cardiac implantable electronic devices (CIEDs) pocket infection is difficult to treat, causing serious clinical outcomes, but little is known for prevention. Results from some studies suggested that pocket irrigation could reduce infection while others showed conflicting results. We pooled the effects of pocket irrigations on the prevention of pocket infection by meta-analysis methods. Read More

    Association of the single nucleotide polymorphism in chromosome 9p21 and chromosome 9q33 with coronary artery disease in Chinese population.
    BMC Cardiovasc Disord 2017 Sep 30;17(1):255. Epub 2017 Sep 30.
    Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
    Background: Our study aims to explore the association of rs7025486 single-nucleotide polymorphisms (SNP) in DAB2IP and rs1333049 on chromosome 9p21.3 with the coronary artery disease in Chinese population.

    Methods: All patients came from the east China area and underwent coronary angiography. Read More

    Socially disadvantaged city districts show a higher incidence of acute ST-elevation myocardial infarctions with elevated cardiovascular risk factors and worse prognosis.
    BMC Cardiovasc Disord 2017 Sep 22;17(1):254. Epub 2017 Sep 22.
    The Bremer Institut für Herz- und Kreislaufforschung (BIHKF) am Klinikum Links der Weser, Bremen, Germany.
    Background: The importance of socioeconomic status (SES) for coronary heart disease (CHD)-morbidity is subject of ongoing scientific investigations. This study was to explore the association between SES in different city-districts of Bremen/Germany and incidence, severity, treatment modalities and prognosis for patients with ST-elevation myocardial infarctions (STEMI).

    Methods: Since 2006 all STEMI-patients from the metropolitan area of Bremen are documented in the Bremen STEMI-registry. Read More

    Aqua walking as an alternative exercise modality during cardiac rehabilitation for coronary artery disease in older patients with lower extremity osteoarthritis.
    BMC Cardiovasc Disord 2017 Sep 21;17(1):252. Epub 2017 Sep 21.
    Department of Health and Exercise Science, Wake Forest University, Winston-Salem, NC, USA.
    Background: The purpose of this study was to examine the effects of aqua walking (AW) on coronary artery disease (CAD) and cardiorespiratory fitness in older adults with osteoarthritis in the lower extremity and compare it with that of traditional over-ground walking.

    Methods: Sixty consecutive eligible patients who had undergone percutaneous coronary intervention for CAD with limited ambulation due to lower extremity osteoarthritis were recruited. They were randomly assigned to the AW program group, treadmill/track walking (TW) program group, or non-exercise control group (CON). Read More

    Complexity of pathomechanisms leading to diastolic heart failure in diabetes mellitus - potential field for therapeutic interventions?
    BMC Cardiovasc Disord 2017 Sep 21;17(1):253. Epub 2017 Sep 21.
    Department of Cardiology, Charité - Universitätsmedizin Berlin, Campus Virchow Klinikum (CVK), Berlin, Germany.
    Advanced glycation end products (AGE) have been implicated in diabetes associated complications. They have been suggested as potential mediators in the progression of diabetic heart failure and as a potential target for treatment. Brunvand et al. Read More

    Financial burden of survivors of medically-managed myocardial infarction and its association with selected social determinants and quality of life in a lower middle income country.
    BMC Cardiovasc Disord 2017 Sep 19;17(1):251. Epub 2017 Sep 19.
    Cardiology Unit, National Hospital Sri Lanka, Colombo, Sri Lanka.
    Background: Burden from ischemic heart disease is rising in Sri Lanka due to the demographic and epidemiological transitions. Documented literature is scarce on quality of life, financial burden and its determinants in relation to myocardial infarction (MI). This study was done to describe the financial burden among the survivors of MI managed only with drugs (i. Read More

    The association of sleep disordered breathing with left ventricular remodeling in CAD patients: a cross-sectional study.
    BMC Cardiovasc Disord 2017 Sep 18;17(1):250. Epub 2017 Sep 18.
    Behavioral Medicine Institute, Lithuanian University of Health Sciences, Vyduno 4, 00135, Palanga, Lithuania.
    Background: There is still insufficient knowledge on the potential effect of mild to moderate sleep-disordered breathing (SDB) that is widely prevalent, often asymptomatic, and largely undiagnosed in patients with stable coronary artery disease (CAD). SDB affects 34% of men and 17% of women aged between 30 and 70. The objective of this study was to evaluate the association between SDB and left ventricular (LV) hypertrophy as well as structural remodeling in stable CAD patients. Read More

    Medical therapy following hospitalization for heart failure with reduced ejection fraction and association with discharge to long-term care: a cross-sectional analysis of the REasons for Geographic And Racial Differences in Stroke (REGARDS) population.
    BMC Cardiovasc Disord 2017 Sep 16;17(1):249. Epub 2017 Sep 16.
    Weill Cornell Medicine, New York, NY, USA.
    Background: Less intensive treatment for heart failure with reduced ejection fraction (HFrEF) may be appropriate for patients in long-term care settings because of limited life expectancy, frailty, comorbidities, and emphasis on quality of life.

    Methods: We compared treatment patterns between REasons for Geographic And Racial Differences in Stroke (REGARDS) study participants discharged to long-term care versus home following HFrEF hospitalizations. We examined medical records and Medicare pharmacy claims for 147 HFrEF hospitalizations among 80 participants to obtain information about discharge disposition and medication prescriptions and fills. Read More

    Anemia in severe heart failure patients: does it predict prognosis?
    BMC Cardiovasc Disord 2017 Sep 16;17(1):248. Epub 2017 Sep 16.
    Department of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
    Background: Anemia is highly prevalent in heart failure (HF) patients. However, the prevalence, clinical impact and prognostic factor of anemia in heart failure patients is widely varies. The aim of this study was to evaluate the prevalence of anemia in patients with HF, to compare baseline clinical characteristic and outcomes of severe HF patients with and without anemia admitted to Gondar University Referral Hospital (GURH), Gondar, Ethiopia. Read More

    Nutrition in primary and secondary prevention of cardiovascular risk in the continental and Mediterranean regions of Croatia.
    BMC Cardiovasc Disord 2017 Sep 16;17(1):247. Epub 2017 Sep 16.
    Division of Cardiology, Department of Internal Medicine, Sveti Duh University Hospital, Zagreb, Croatia.
    Background: The aim of this observational study was to evaluate the effect of Mediterranean and continental nutrition on cardiovascular risk in patients with acute and chronic coronary heart disease in Croatia.

    Methods: The study included 1284 patients who were hospitalized in a 28-month period due to acute or chronic ischaemic heart disease in hospitals across Croatia. An individual questionnaire was prepared which enabled recording of various cardiovascular risk factors. Read More

    Resting heart rate and impaired glucose regulation in middle-aged and elderly Chinese people: a cross-sectional analysis.
    BMC Cardiovasc Disord 2017 Sep 13;17(1):246. Epub 2017 Sep 13.
    Department of Endocrinology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, 1665 Kongjiang Road, Shanghai, 200092, China.
    Background: Elevated resting heart rate (RHR) has been reported to be associated with metabolic syndrome and type 2 diabetes. The aim of this study was to explore whether a positive relationship exists between RHR and impaired glucose regulation (IGR) among middle-aged and older Chinese individuals.

    Methods: We conducted a cross-sectional analysis that included a total of 9898 subjects (3194 men and 6704 women) in a Chinese population. Read More

    Determination of risk factors affecting the in-hospital prognosis of patients with acute ST segment elevation myocardial infarction after percutaneous coronary intervention.
    BMC Cardiovasc Disord 2017 Sep 12;17(1):243. Epub 2017 Sep 12.
    School of Nursing, Guangdong Pharmaceutical University, Guangzhou, 510310, China.
    Background: To determine the factors affecting the in-hospital prognosis of patients with acute ST segment elevation myocardial infarction (STEMI) after percutaneous coronary intervention (PCI), and to establish its prognostic discriminant model.

    Methods: A total of 701 consecutive STEMI patients undergoing PCI were enrolled in this study. The patients were divided into two groups, good prognosis and poor prognosis, based on whether the patient had adverse outcomes (death or heart function ≥ grade III) at discharge. Read More

    Barriers to lifestyle changes for prevention of cardiovascular disease - a survey among 40-60-year old Danes.
    BMC Cardiovasc Disord 2017 Sep 12;17(1):245. Epub 2017 Sep 12.
    Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, J.B.Winsløwvej 9, DK-5000, Odense, Denmark.
    Background: Elimination of modifiable risk factors including unhealthy lifestyle has the potential for prevention of 80% of cardiovascular disease cases. The present study focuses on disclosing barriers for maintaining specific lifestyle changes by exploring associations between perceiving these barriers and various sociodemographic and health-related characteristics.

    Methods: Data were collected through a web-based questionnaire survey and included 962 respondents who initially accepted treatment for a hypothetical cardiovascular risk, and who subsequently stated that they preferred lifestyle changes to medication. Read More

    One symptom, two arrhythmias: the rare and the even rarer.
    BMC Cardiovasc Disord 2017 Sep 12;17(1):244. Epub 2017 Sep 12.
    Department of Cardiology & Angiology, Hannover Medical School, Carl-Neuberg-Strasse 1, D-30625, Hannover, Germany.
    Background: Wolff-Parkinson-White (WPW) syndrome and idiopathic left ventricular tachycardia (ILVT) are rare and up to now the coexistence of both entities has rarely been reported. In patients with ventricular preexcitation the underlying mechanism of paroxysmal tachycardia most likely is atrioventricular reentrant tachycardia (AVRT). However, without ECG documentation of the tachycardia diagnosis of the underlying mechanism cannot be made due to similar clinical presentation of AVRT and ILVT. Read More

    Chronic kidney disease and diabetes associated with long-term outcomes in patients receiving percutaneous coronary intervention.
    BMC Cardiovasc Disord 2017 Sep 11;17(1):242. Epub 2017 Sep 11.
    Division of Pediatric General Medicine, Department of Pediatrics, Chang Gung Memorial Hospital at Linko, No. 5, Fu-Hsin Street, Kweishan, Taoyuan, Taiwan.
    Background: The effect of diabetes mellitus (DM) and chronic kidney disease (CKD) on long-term outcomes in patients receiving percutaneous coronary intervention (PCI) is unclear.

    Methods: A total of 1394 patients who underwent PCI were prospectively enrolled and divided into 4 groups according to the presence or absence of DM or CKD. Baseline characteristics, risk factors, medications, and angiographic findings were compared. Read More

    Medical and sociodemographic factors predict persistent smoking after coronary events.
    BMC Cardiovasc Disord 2017 Sep 6;17(1):241. Epub 2017 Sep 6.
    Department of Medicine, Drammen Hospital, PB 800, 3004, Drammen, Norway.
    Background: Understanding the determinants of persistent smoking after a coronary event constitutes the basis of modelling interventions of smoking cessation in secondary prevention programs. We aim to identify the potentially modifiable medical, sociodemographic and psychosocial factors, comprising the study factors, associated with unfavourable risk factor control after CHD events.

    Methods: A cross-sectional explorative study used logistic regression analysis to investigate the association between study factors and smoking status in 1083 patients hospitalized with myocardial infarction and/or coronary revascularization. Read More

    Long-term outcomes of coronary artery bypass grafting versus stent-PCI for unprotected left main disease: a meta-analysis.
    BMC Cardiovasc Disord 2017 Sep 6;17(1):240. Epub 2017 Sep 6.
    Division of Cardiology, Department of Medical and Surgical Sciences, "Magna Graecia" University, 88100, Catanzaro, Italy.
    Background: Coronary artery bypass graft (CABG) surgery has traditionally represented the standard of care for left main coronary artery (LMCA) disease. However, percutaneous coronary intervention with stent implantation (PCI) has more recently emerged as a valuable alternative. The long-time awaited results of the largest randomized trials on the long-term impact of PCI versus CABG in LMCA disease, the newly published NOBLE and EXCEL studies, revealed contrasting results. Read More

    Sildenafil dosed concomitantly with bosentan for adult pulmonary arterial hypertension in a randomized controlled trial.
    BMC Cardiovasc Disord 2017 Sep 6;17(1):239. Epub 2017 Sep 6.
    Pfizer Inc, 4 E Carol Ave, Burlingame, New York, CA, 94010, USA.
    Background: Few controlled clinical trials exist to support oral combination therapy in pulmonary arterial hypertension (PAH).

    Methods: Patients with PAH (idiopathic [IPAH] or associated with connective tissue disease [APAH-CTD]) taking bosentan (62.5 or 125 mg twice daily at a stable dose for ≥3 months) were randomized (1:1) to sildenafil (20 mg, 3 times daily; n = 50) or placebo (n = 53). Read More

    Comparative effectiveness of rivaroxaban versus warfarin or dabigatran for the treatment of patients with non-valvular atrial fibrillation.
    BMC Cardiovasc Disord 2017 Sep 6;17(1):238. Epub 2017 Sep 6.
    Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
    Background: Rivaroxaban is an oral anticoagulant approved in the US for prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation (NVAF). We determined the effectiveness and associated risks of rivaroxaban versus other oral anticoagulants in a large real-world population.

    Methods: We selected NVAF patients initiating oral anticoagulant use in 2010-2014 enrolled in MarketScan databases. Read More

    Myocardial infarction during anaphylaxis in a young healthy male with normal coronary arteries- is epinephrine the culprit?
    BMC Cardiovasc Disord 2017 Sep 4;17(1):237. Epub 2017 Sep 4.
    National Hospital, Colombo, Sri Lanka.
    Background: Anaphylaxis is an acute, potentially fatal medical emergency. Myocardial injury or infarction in the setting of an anaphylaxis can be due the anaphylaxis itself, when it is known as Kounis syndrome or it can also be due to the effect of epinephrine treatment. Epinephrine is considered as the cornerstone in management of anaphylaxis. Read More

    Adherence and outcomes to direct oral anticoagulants among patients with atrial fibrillation: findings from the veterans health administration.
    BMC Cardiovasc Disord 2017 Sep 2;17(1):236. Epub 2017 Sep 2.
    Division of Cardiology - Campus Box B130, University of Colorado Anschutz Medical Campus, 12631 E. 17th Avenue, Aurora, CO, 80045, USA.
    Background: The direct oral anticoagulants (DOACs) reduce the risk of stroke in moderate to high-risk patients with non-valvular atrial fibrillation (AF). Yet, concerns remain regarding its routine use in real world practice. We sought to describe adherence patterns and the association between adherence and outcomes to the DOACs among outpatients with AF. Read More

    The top tertile of hematocrit change during hospitalization is associated with lower risk of mortality in acute heart failure patients.
    BMC Cardiovasc Disord 2017 Sep 2;17(1):235. Epub 2017 Sep 2.
    State Key Laboratory of Organ Failure Research, Department of Cardiology, Nanfang Hospital Southern Medical University, 1838 North Guangzhou Avenue, Guangzhou, 510515, China.
    Background: Hemoconcentration has been proposed as surrogate for changes in volume status among patients hospitalized with acute heart failure (AHF) and is associated with a favorable outcome. However, there is a dearth of research assessing the clinical outcomes of hospitalized patients with hemoconcentration, hemodilution and unchanged volume status.

    Methods: We enrolled 510 consecutive patients hospitalized for AHF from April 2011 to July 2015. Read More

    Efficacy and safety of transcatheter aortic valve replacement in aortic stenosis patients at low to moderate surgical risk: a comprehensive meta-analysis.
    BMC Cardiovasc Disord 2017 Aug 24;17(1):234. Epub 2017 Aug 24.
    Faculty of Medicine, Damascus University, Damascus, Syria.
    Background: Recently, transcatheter aortic valve replacement (TAVR) has become the procedure of choice in high surgical risk patients with aortic stenosis (AS). However, its value is still debated in operable AS cases. We performed this meta-analysis to compare the safety and efficacy of TAVR to surgical aortic valve replacement (SAVR) in low-to-moderate surgical risk patients with AS. Read More

    PR interval prolongation in coronary patients or risk equivalent: excess risk of ischemic stroke and vascular pathophysiological insights.
    BMC Cardiovasc Disord 2017 Aug 24;17(1):233. Epub 2017 Aug 24.
    Division of Cardiology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, Rm 1928, Block K, Hong Kong, China.
    Background: Whether PR prolongation independently predicts new-onset ischemic events of myocardial infarction and stroke was unclear. Underlying pathophysiological mechanisms of PR prolongation leading to adverse cardiovascular events were poorly understood. We investigated the role of PR prolongation in pathophysiologically-related adverse cardiovascular events and underlying mechanisms. Read More

    2-Dimensional Speckle Tracking Echocardiography predicts severe coronary artery disease in women with normal left ventricular function: a case-control study.
    BMC Cardiovasc Disord 2017 Aug 24;17(1):231. Epub 2017 Aug 24.
    Department of Cardiovascular Diseases, Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA.
    Background: Women who have coronary artery disease (CAD) often present with atypical symptoms that may lead to misdiagnosis. We assessed strain, systolic strain rate and left ventricular dyssynchrony with 2- dimensional- speckle tracking echocardiography to evaluate its use as a non-invasive method for detecting CAD in women with normal ejection fraction compared with healthy women controls with a normal angiogram.

    Methods: We included 35 women with CAD confirmed by coronary angiography and a positive exercise stress echocardiography and 35 women in a control group with a low pretest probability of CAD, normal angiogram and a normal stress echocardiography with normal EF. Read More

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