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    770 results match your criteria BMC Anesthesiology[Journal]

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    Effects of dexmedetomidine on TNF-α and interleukin-2 in serum of rats with severe craniocerebral injury.
    BMC Anesthesiol 2017 Sep 20;17(1):130. Epub 2017 Sep 20.
    Department of Anesthesiology II, Affiliated Zhongshan Hospital of Dalian University, No. 6 of Jiefang Street, Zhongshan District, Dalian, 116001, China.
    Background: Dexmedetomidine is a highly selective adrenergic receptor agonist, which has a dose-dependent sedative hypnotic effect. Furthermore, it also has pharmacological properties, and the ability to inhibit sympathetic activity and improve cardiovascular stability during an operation. However, its protective effect on patients with severe craniocerebral injury in the perioperative period remains unclear. Read More

    Effects of lubrication on air-sealing performance of a pediatric cuffed tracheal tube.
    BMC Anesthesiol 2017 Sep 19;17(1):129. Epub 2017 Sep 19.
    Department of Anesthesiology, Mizonokuchi Hospital, Teikyo University School of Medicine, 3-8-3 Mizonokuchi, Takatsu-ku, Kawasaki, 213-8507, Japan.
    Background: Lubrication of cuffed tracheal tubes (CTTs) reduces liquid leakage. However, it is not clear how cuff lubrication influences air leakage. We aimed to test the hypothesis that pretreatment with K-Y jelly, a water-soluble lubricant, would improve the air-sealing performance of pediatric CTTs in a model study. Read More

    Levosimendan combined with epinephrine improves rescue outcomes in a rat model of lipid-based resuscitation from bupivacaine-induced cardiac arrest.
    BMC Anesthesiol 2017 Sep 15;17(1):128. Epub 2017 Sep 15.
    Department of Anaesthesiology, the First Affiliated Hospital, Wenzhou Medical University, Zhejiang, China.
    Background: The effectiveness of a combination of a lipid emulsion with epinephrine in reversing local anesthetic-induced cardiac arrest has been confirmed. The combination of a lipid emulsion with levosimendan, was shown to be superior to administration of a lipid emulsion alone with regard to successful resuscitation. In this study, we compared the reversal effects of levosimendan, epinephrine, and a combination of the two agents in lipid-based resuscitation in a rat model of bupivacaine-induced cardiac arrest. Read More

    Incidence and severity of postoperative sore throat: a randomized comparison of Glidescope with Macintosh laryngoscope.
    BMC Anesthesiol 2017 Sep 12;17(1):127. Epub 2017 Sep 12.
    Department of Anesthesiology, King Khalid Hospital, Hail, Saudi Arabia.
    Background: Postoperative sore throat (POST) is a common problem following endotracheal (ET) intubation during general anesthesia. The objective was to compare the incidence and severity of POST during routine intubation with Glidescope (GL) and Macintosh laryngoscope (MCL).

    Methods: One hundred forty adult patients ASA I and II with normal airway, scheduled to undergo elective surgery under GA requiring ET intubation were enrolled in this prospective randomized study and were randomly divided in two groups, GL and MCL. Read More

    Determination of the optimal inspiratory pressure providing adequate ventilation while minimizing gastric insufflation using real-time ultrasonography in Chinese children: a prospective, randomized, double-blind study.
    BMC Anesthesiol 2017 Sep 11;17(1):126. Epub 2017 Sep 11.
    Department of Anesthesiology, Critical Care and Pain Medicine, The Second Affiliated Hospital and Yuying Children Hospital of Wenzhou Medical University, West College Road 109, Wenzhou, 325027, China.
    Background: During facemask ventilation, gastric insufflation is defined as appearance of a comet-tail or an acoustic shadow on ultrasonography. Ultrasonographic measurement of antral cross-section area (CSA) may reflect an insufflated antrum and provide interesting semi-quantitative data in regard to the gastric insufflation. This study aimed to determine the appropriate level of inspiratory pressure sufficient to provide adequate pulmonary ventilation with a lower occurrence of gastric insufflation during facemask pressure-controlled ventilation using real-time ultrasonography in paralyzed children. Read More

    Comparison of the Supreme™ and ProSeal™ laryngeal mask airways in infants: a prospective randomised clinical study.
    BMC Anesthesiol 2017 Sep 5;17(1):125. Epub 2017 Sep 5.
    Department of Paediatric Surgery, Sisli Hamidiye Etfal Education and Research Hospital, Halaskargazi Cad., Etfal Sok, 34377, Istanbul, Turkey.
    Background: The Supreme™ and ProSeal™ laryngeal mask airways (LMAs) are widely used in paediatric anaesthesia; however, LMA use in infants is limited because many anaesthesiologists prefer to use tracheal intubation in infants. In this study, we compared the Supreme and ProSeal LMAs in infants by measuring their performance characteristics, including insertion features, ventilation parameters, induced changes in haemodynamics and rates of postoperative complications.

    Methods: Infants of ASA physical status I scheduled for elective, minor, lower abdominal surgery were divided into two groups: the Supreme LMA group and the ProSeal LMA group. Read More

    TREK-1 mediates isoflurane-induced cytotoxicity in astrocytes.
    BMC Anesthesiol 2017 Sep 5;17(1):124. Epub 2017 Sep 5.
    Department of Anesthesiology and Perioperative Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.
    Background: There are growing concerns that anaesthetic exposure can cause extensive apoptotic degeneration of neurons and the impairment of normal synaptic development and remodelling. However, little attention has been paid to exploring the possible cytotoxicity of inhalation anaesthetics, such as isoflurane, in astrocytes. In this research, we determined that prolonged exposure to an inhalation anaesthetic caused cytotoxicity in astrocytes, and we identified the underlying molecular mechanism responsible for this process. Read More


    Ten important articles on noninvasive ventilation in critically ill patients and insights for the future: A report of expert opinions.
    BMC Anesthesiol 2017 Sep 4;17(1):122. Epub 2017 Sep 4.
    Department of Biopathology and Medical Biotechnologies (DIBIMED). Section of Anestesia, Analgesia, Intensive Care and Emergency, Policlinico P. Giaccone, University of Palermo, Palermo, Italy.
    Background: Noninvasive ventilation is used worldwide in many settings. Its effectiveness has been proven for common clinical conditions in critical care such as cardiogenic pulmonary edema and chronic obstructive pulmonary disease exacerbations. Since the first pioneering studies of noninvasive ventilation in critical care in the late 1980s, thousands of studies and articles have been published on this topic. Read More

    Hydrogen sulfide attenuates isoflurane-induced neuroapoptosis and cognitive impairment in the developing rat brain.
    BMC Anesthesiol 2017 Sep 5;17(1):123. Epub 2017 Sep 5.
    Department of Veterinary Medicine, College of Veterinary Medicine, Northeast Agricultural University, No. 600 of Changjiang Road, Xiangfang District, Harbin, Heilongjiang Province, China.
    Background: Isoflurane-induced neuroapoptosis and cognitive impairment has been previously reported. Hydrogen sulfide (H2S) has been shown to be a neuromodulator that is thought to have anti-apoptotic, anti-inflammatory, and anti-oxidative benefits. However, it is not known if H2S is protective against anesthesia-induced apoptosis and cognitive defects. Read More

    Pediatric supraglottic airway devices in clinical practice: A prospective observational study.
    BMC Anesthesiol 2017 Sep 2;17(1):119. Epub 2017 Sep 2.
    Department of Anaesthesiology and Pain Therapy, Inselspital, University Hospital Bern, University of Bern, Freiburgstrasse, 3010, Bern, Switzerland.
    Background: Supraglottic airway devices (SGA) are commonly used in pediatric anesthesia and serve as primary or back-up devices for difficult airway management. Most SGA are marketed without proper clinical evaluation. The purpose of this study was to evaluate the performance of the pediatric LMA Supreme™, Air-Q® and Ambu® Aura-i™. Read More

    Multicenter assessment of sedation and delirium practices in the intensive care units in Poland - is this common practice in Eastern Europe?
    BMC Anesthesiol 2017 Sep 2;17(1):120. Epub 2017 Sep 2.
    Department of Medicine/Allergy, Pulmonary and Critical Care, Vanderbilt University School ofMedicine, Vetaran's Affairs Geriatric Research Education Clinical Center (GRECC) for Tennessee Valley, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN, USA.
    Background: The majority of critically ill patients experience distress during their stay in the Intensive Care Unit (ICU), resulting from systemic illness, multiple interventions and environmental factors. Providing humane care should address concomitant treatment of pain, agitation and delirium. The use of sedation and approaches to ICU delirium should be monitored according to structured guidelines. Read More

    The role of increased body mass index in outcomes of sepsis: a systematic review and meta-analysis.
    BMC Anesthesiol 2017 Aug 31;17(1):118. Epub 2017 Aug 31.
    Department of Anesthesiology and Intensive Care Medicine, the First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, 310003, China.
    Background: The role of increased body mass index (BMI) in sepsis is controversial. We aimed to evaluate the associations between overweight (25 kg/m(2) < BMI ≤ 29.9 kg/m(2)), obese (30 kg/m(2) < BMI ≤ 39. Read More

    Effects and mechanism of dexmedetomidine on neuronal cell injury induced by hypoxia-ischemia.
    BMC Anesthesiol 2017 Aug 30;17(1):117. Epub 2017 Aug 30.
    Department of Anesthesiology, Qilu Hospital of Shandong University, No. 107, Wenhua West Road, Jinan, Shandong, 250012, China.
    Background: The present study aims to investigate the protective effects of dexmedetomidine (DMED) on hypoxia ischemia injury induced by oxygen and glucose deprivation (OGD) in PC12 and primary neuronal cells.

    Methods: PC12 cells exposed to OGD was used to establish ischemia model. The OGD-induced cell injury was evaluated by alterations of cell viability, apoptosis and expressions of apoptosis-associated proteins. Read More

    Assessing advances in regional anesthesia by their portrayals in meta-analyses: an alternative view on recent progress.
    BMC Anesthesiol 2017 Aug 29;17(1):112. Epub 2017 Aug 29.
    Department of Anesthesiology, Brigham and Women's Hospital, 75 Francis St, Boston, MA, 20115, USA.
    Background: The aim of this study was to delineate research reflecting advances in regional/local anesthesia where recent clinical progress was clearly defined by meta-analysis.

    Methods: We conducted a search to identify all articles with meta-analyses of randomized clinical trials related to the field of regional/local anesthesia. From 279 titles, after multiple exclusions, 16 meta-analyses on important clinical practice developments with high potential for a positive conclusion on the effectiveness of the treatment were left for the assessment. Read More

    Combined spinal-epidural anesthesia for cesarean delivery in a patient with cor triloculare biventriculare.
    BMC Anesthesiol 2017 Aug 29;17(1):115. Epub 2017 Aug 29.
    Department of Anesthesiology, The Affiliated Hospital of Xuzhou Medical University, NO. 99 Huaihai Road, Quanshan District, Xuzhou city, Jiangsu Province, China.
    Background: Cor triloculare biventriculare accounts for approximately 0.31% of cases of congenital heart disease (CHD). Moreover, people with cor triloculare biventriculare always have shorter life spans, and cases of gestation are rare. Read More

    Influence of the postoperative inflammatory response on cognitive decline in elderly patients undergoing on-pump cardiac surgery: a controlled, prospective observational study.
    BMC Anesthesiol 2017 Aug 29;17(1):113. Epub 2017 Aug 29.
    Department of Anaesthesia and Intensive Therapy, Semmelweis University, P.O.B. 2, Budapest, H-1428, Hungary.
    Background: The role of non-infective inflammatory response (IR) in the aetiology of postoperative cognitive dysfunction (POCD) is still controversial. The aim of this controlled, prospective observational study was to assess the possible relationship between the grade of IR, defined by procalcitonin (PCT) changes, and development of POCD related to cardiac surgery.

    Methods: Forty-two patients, who were ≥ 60 years of age and scheduled for elective cardiac surgery, were separated into the low inflammatory (LIR) and high inflammatory (HIR) response groups based on their PCT levels measured on the first postoperative day. Read More

    Anesthetic management of a pediatric patient with Electron Transfer Flavoprotein Dehydrogenase deficiency (ETFDH) and acute appendicitis: case report and review of the literature.
    BMC Anesthesiol 2017 Aug 29;17(1):116. Epub 2017 Aug 29.
    Department of Pediatric Surgery, University Hospital of Crete, 71110, Herakllion, Greece.
    Background: Mitochondria are the energy producing organelles practically in every human cell except erythrocytes. Indeed mitochondria are widespread in high energy requiring organs like brain, heart and muscles. Currently there are no clinical trials supporting with clear evidence which is the most suitable surgical or anesthetic management of a patient with known mitochondrial disease presenting with surgical disorders. Read More

    Intravenous theophylline is the most effective intervention to prolong EEG seizure duration in patients undergoing electroconvulsive therapy.
    BMC Anesthesiol 2017 Aug 29;17(1):114. Epub 2017 Aug 29.
    Department of Anesthesiology, University Hospital of Erlangen, Krankenhausstrasse 12, 91054, Erlangen, Germany.
    Background: Seizure duration in electroconvulsive therapy (ECT) is positively related with patients' outcome. This study sought to investigate the impact of anesthetic management on seizure duration, and the impact of selected drugs (theophylline, remifentanil, S-ketamine) on seizure duration.

    Methods: Retrospective analysis of all patients undergoing ECT at our institution from January 2011 to April 2012 was performed based on electronic medical chart and review of existing quality improvement data. Read More

    Ketamine attenuates the glutamatergic neurotransmission in the ventral posteromedial nucleus slices of rats.
    BMC Anesthesiol 2017 Aug 23;17(1):111. Epub 2017 Aug 23.
    Guizhou Key Laboratory of Anesthesia and Organ Protection, Zunyi Medical College, Dalian Road, Zunyi, Guizhou, 201, China.
    Background: Ketamine is a frequently used intravenous anesthetic, which can reversibly induce loss of consciousness (LOC). Previous studies have demonstrated that thalamocortical system is critical for information transmission and integration in the brain. The ventral posteromedial nucleus (VPM) is a critical component of thalamocortical system. Read More

    Adequate interval for the monitoring of vital signs during endotracheal intubation.
    BMC Anesthesiol 2017 Aug 22;17(1):110. Epub 2017 Aug 22.
    Department of Anesthesiology and Pain Medicine, Severance Hospital, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 120-752, Republic of Korea.
    Background: In the perioperative period, it may be inappropriate to monitor vital signs during endotracheal intubation using the same interval as during a hemodynamically stable period. The aim of the present study was to determine whether it is appropriate to use the same intervals used during the endotracheal intubation and stable periods to monitor vital signs of patients under general anesthesia.

    Methods: The mean arterial pressure (MAP) and heart rate (HR) were continuously measured during endotracheal intubation (15 min after intubation) and hemodynamically stable (15 min before skin incision) periods in 24 general anesthesia patients. Read More

    Minimal shedding of the glycocalyx layer during abdominal hysterectomy.
    BMC Anesthesiol 2017 Aug 22;17(1):107. Epub 2017 Aug 22.
    Department of Anaesthesiology and Intensive Care, Riga Stradins University and Paul Stradins Clinical University Hospital, Riga, Latvia.
    Background: Surgery with and without hypervolaemia may cause shedding (breakdown) of the endothelial glycocalyx layer, but the severity of this problem is unclear.

    Methods: In this preliminary report of a larger clinical trial, the plasma and urine concentrations of three biomarkers of glycocalyx shedding (syndecan-1, hyaluronic acid and heparan sulfate) were measured in seven patients before, during, and after open hysterectomy. The fluid therapy consisted of 25 ml/kg (approximately 2 l) of Ringer's lactate, which was infused over 30 min when the surgery started. Read More

    Recovery and prediction of postoperative muscle power - is it still a problem?
    BMC Anesthesiol 2017 Aug 22;17(1):108. Epub 2017 Aug 22.
    Department of Anaesthesia and Intensive Care Medicine, University of Marburg, Baldinger Strasse, D-35033, Marburg, Germany.
    Background: In the postoperative period, immediate recovery of muscular power is essential for patient safety, but this can be affected by anaesthetic drugs, opioids and neuromuscular blocking agents (NMBA). In this cohort study, we evaluated anaesthetic and patient-related factors contributing to reduced postoperative muscle power and pulse oximetric saturation.

    Methods: We prospectively observed 615 patients scheduled for minor surgery. Read More

    Impact of intrathecal morphine analgesia on the incidence of pulmonary complications after cardiac surgery: a single center propensity-matched cohort study.
    BMC Anesthesiol 2017 Aug 22;17(1):109. Epub 2017 Aug 22.
    Department of Anesthesiology, Pharmacology and Intensive Care, University Hospital of Geneva, Rue Gabrielle-Perret-Gentil 4, -1211, Geneva, CH, Switzerland.
    Background: Acute pain and systemic opioids may both negatively impact respiratory function after cardiac surgery. This study analyzes the local practice of using intrathecal morphine analgesia (ITMA) with minimal parenteral opioid administration in cardiac surgery, specifically the impact on postoperative pulmonary complications (PPCs).

    Methods: Data from adult patients who underwent elective cardiac surgery between January 2002, and December 2013 in a single center were analyzed. Read More

    Comparison of the trapezius and the adductor pollicis muscle as predictor of good intubating conditions: a randomized controlled trial.
    BMC Anesthesiol 2017 Aug 17;17(1):106. Epub 2017 Aug 17.
    Department of Anesthesia and Intensive Care Medicine, University of Rostock, Rostock, Germany.
    Background: Adequate muscle relaxation is important for ensuring optimal conditions for intubation. Although acceleromyography of the adductor pollicis muscle is commonly used to assess conditions for intubation, we hypothesized that acceleromyography of the trapezius is more indicative of optimal intubating conditions. The primary outcome was the difference between both measurement sites with regard to prediction of good or acceptable intubating conditions. Read More

    Systemic LPS resulted in a transient hippocampus malfunction but a prolonged corpus callosum injury.
    BMC Anesthesiol 2017 Aug 14;17(1):105. Epub 2017 Aug 14.
    Department of Anesthesiology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, People's Republic of China.
    Background: To investigate the effect of systemic lipopolysaccharide (LPS) on function of hippocampus and corpus callosum (CC) in adult rats.

    Methods: Adult rats with mature white matter tract were divided into systemic LPS and saline injection groups. Animal were euthanized following 3 daily injections (day 3) and 3-day after cessation of injections (day 6). Read More

    Incidence and risk factors of chronic pain following hysterectomy among Southern Jiangsu Chinese Women.
    BMC Anesthesiol 2017 Aug 11;17(1):103. Epub 2017 Aug 11.
    The Affiliated Yixing Hospital of Jiangsu University, 75 Tongzhenguan Road, Yixing, Jiangsu, 214200, People's Republic of China.
    Background: Chronic post-surgical pain (CPSP) after hysterectomy has been recognized as a major clinical problem in the Western World. Reports on post-hysterectomy pain are relatively scarce in China. The aim of the current study was to prospectively investigate the incidence and the potential risk factors of CPSP at 3 months following hysterectomy in Chinese population. Read More

    A novel thermal compression device for perioperative warming: a randomized trial for feasibility and efficacy.
    BMC Anesthesiol 2017 Aug 11;17(1):102. Epub 2017 Aug 11.
    Department of Anesthesiology, Stanford University, Stanford, USA.
    Background: Inadvertent perioperative hypothermia (IPH) leads to surgical complications and increases length of stay. IPH rates are high with the current standard of care, forced air warming (FAW). Our hypothesis is that a prototype thermal compression device that heats the popliteal fossa and soles of the feet, with lower leg compression, increases perioperative temperatures and reduces IPH compared to the current standard of care. Read More

    Randomized comparison of sevoflurane versus propofol-remifentanil on the cardioprotective effects in elderly patients with coronary heart disease.
    BMC Anesthesiol 2017 Aug 11;17(1):104. Epub 2017 Aug 11.
    Department of Anesthesiology, 1st affiliated hospital of Wenzhou Medical University, 1#, nanbaixiang, Ouhai District, Wenzhou, 325000, China.
    Background: It is skeptical about cardioprotective property of sevoflurane in patients undergoing noncardiac surgery, especially in the elderly patients with coronary heart disease. We hypothesized that long duration of sevoflurane inhalation in noncardiac surgery could ameliorate myocardial damage in such patients.

    Methods: This was a randomized, prospective study. Read More

    Development of an algorithm using clinical tests to avoid post-operative residual neuromuscular block.
    BMC Anesthesiol 2017 Aug 4;17(1):101. Epub 2017 Aug 4.
    Klinik für Anaesthesiologie, Klinikum rechts der Isar, Technische Universität München, Munich, Ismaninger Str. 22, 81675, Munich, Germany.
    Background: Quantitative neuromuscular monitoring is the gold standard to detect postoperative residual curarization (PORC). Many anesthesiologists, however, use insensitive, qualitative neuromuscular monitoring or unreliable, clinical tests. Goal of this multicentre, prospective, double-blinded, assessor controlled study was to develop an algorithm of muscle function tests to identify PORC. Read More

    Aspirations to become an anaesthetist: longitudinal study of historical trends and trajectories of UK-qualified doctors' early career choices and of factors that have influenced their choices.
    BMC Anesthesiol 2017 Jul 25;17(1):100. Epub 2017 Jul 25.
    UK Medical Careers Research Group, Unit of Health-Care Epidemiology, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
    Background: It is important to inform medical educators and workforce planners in Anaesthesia about early career choices for the specialty, factors that influence them and to elucidate how recent choices of men and women doctors relate to the overall historical trends in the specialty's popularity.

    Methods: We analysed longitudinal data on career choice, based on self-completed questionnaires, from national year-of-qualification cohorts of UK-trained doctors from 1974 to 2012 surveyed one, three and 5 years post-qualification. Career destination data 10 years post-qualification were used for qualifiers between 1993 and 2002, to investigate the association between early choice and later destinations. Read More

    Assessment of cerebral circulation in a porcine model of intravenously given E. coli induced fulminant sepsis.
    BMC Anesthesiol 2017 Jul 24;17(1):98. Epub 2017 Jul 24.
    Department of Anesthesiology and Intensive Care, University of Debrecen, Faculty of Medicine, Nagyerdei krt. 98, Debrecen, H 4032, Hungary.
    Background: The aim of the present work was to assess cerebral hemodynamic changes in a porcine model of E.coli induced fulminant sepsis.

    Methods: Nineteen healthy female Hungahib pigs, 10-12 weeks old, randomly assigned into two groups: Control (n = 9) or Septic Group (n = 10). Read More

    Surgical frailty assessment: a missed opportunity.
    BMC Anesthesiol 2017 Jul 24;17(1):99. Epub 2017 Jul 24.
    Department of Surgery, 2D, Walter C Mackenzie Health Sciences Centre, University of Alberta, 8440-112 Street, Edmonton, AB, T6G 2B7, Canada.
    Background: Preoperative frailty predicts adverse postoperative outcomes. Despite the advantages of incorporating frailty assessment into surgical settings, there is limited research on surgical healthcare professionals' use of frailty assessment for perioperative care.

    Methods: Healthcare professionals caring for patients enrolled at a Canadian teaching hospital were surveyed to assess their perceptions of frailty, as well as attitudes towards and practices for frail patients. Read More

    The communication between patient relatives and physicians in intensive care units.
    BMC Anesthesiol 2017 Jul 17;17(1):97. Epub 2017 Jul 17.
    Department of Anesthesiology, Selcuk University, Medical Faculty, Alaadin Keykubat Yerleskesi, Konya, Turkey.
    Background: Patients in intensive care units (ICUs) are often physically unable to communicate with their physicians. Thus, the sharing of information about the on-going treatment of the patients in ICUs is directly related to the communication attitudes governing a patient's relatives and the physician. This study aims to analyze the attitudes displayed by the relatives of patients and the physician with the purpose of determining the communication between the two parties. Read More

    Assessing anesthesiology residents' out-of-the-operating-room (OOOR) emergent airway management.
    BMC Anesthesiol 2017 Jul 15;17(1):96. Epub 2017 Jul 15.
    Department of Anesthesiology, University of Michigan, 1500 E. Medical Center Drive, 1H247 University Hospital, SPC 5048, Ann Arbor, MI, 48103, USA.
    Background: At many academic institutions, anesthesiology residents are responsible for managing emergent intubations outside of the operating room (OOOR), with complications estimated to be as high as 39%. In order to create an OOOR training curriculum, we evaluated residents' familiarity with the content and correct adherence to the American Society of Anesthesiologists' Difficult Airway Algorithm (ASA DAA).

    Methods: Residents completed a pre-simulation multiple-choice survey measuring their understanding and use of the DAA. Read More

    Case report: perioperative management of caesarean section for a parturient with mitochondrial myopathy.
    BMC Anesthesiol 2017 Jul 12;17(1):94. Epub 2017 Jul 12.
    Department of Anesthesiology, Qilu Hospital of Shandong University (Qingdao), No.758 Hefei Road, Qingdao, 266035, People's Republic of China.
    Background: Mitochondrial myopathies represent a group of disorders caused by mitochondrial defects that disrupt energy production. Most patients have issues from infancy to early childhood. Pregnancy in women with mitochondrial myopathy is uncommon and the management for these parturients is full of challenges. Read More

    The current level of shared decision-making in anesthesiology: an exploratory study.
    BMC Anesthesiol 2017 Jul 12;17(1):95. Epub 2017 Jul 12.
    Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands.
    Background: Shared decision-making (SDM) seeks to involve both patients and clinicians in decision-making about possible health management strategies, using patients' preferences and best available evidence. SDM seems readily applicable in anesthesiology. We aimed to determine the current level of SDM among preoperative patients and anesthesiology clinicians. Read More

    End-of-life perceptions among physicians in intensive care units managed by anesthesiologists in Germany: a survey about structure, current implementation and deficits.
    BMC Anesthesiol 2017 Jul 11;17(1):93. Epub 2017 Jul 11.
    Universitätsklinik für Anästhesiologie, op. Intensivmedizin, Rettungsmedizin, Schmerztherapie der Ruhr-Universität Bochum, Klinikum Herford, Herford, Germany.
    Background: Structural aspects and current practice about end-of-life (EOL) decisions in German intensive care units (ICUs) managed by anesthesiologists are unknown. A survey among intensive care anesthesiologists has been conducted to explore current practice, barriers and opinions on EOL decisions in ICU.

    Methods: In November 2015, all members of the German Society of Anesthesiology and Intensive Care Medicine (DGAI) and the Association of German Anesthesiologists (BDA) were asked to participate in an online survey to rate the presence or absence and the importance of 50 items. Read More

    Combatting pain after orthopedic/trauma surgery- perioperative oral extended-release tapentadol vs. extended-release oxycodone/naloxone.
    BMC Anesthesiol 2017 Jul 11;17(1):91. Epub 2017 Jul 11.
    Institute for Biostatistics, Hannover Medical School, Carl-Neuberg-Str. 1, D-30652, Hannover, Germany.
    Background: High post-operative pain scores after "minor" orthopedic/trauma surgery are in part attributed to inadequate prescription of opioid analgesics. Novel concepts aiming to achieve sufficient analgesia while minimizing opioid-related side effects by avoiding fluctuating plasma levels are based on perioperative oral administration of extended-release opioids beginning with the first dose pre-operatively. This is the first study to evaluate analgesic efficacy and side effect rates of extended-release tapentadol compared to oxycodone/naloxone following orthopedic/trauma surgery. Read More

    Cyclic PaO2 oscillations assessed in the renal microcirculation: correlation with tidal volume in a porcine model of lung lavage.
    BMC Anesthesiol 2017 Jul 11;17(1):92. Epub 2017 Jul 11.
    Department of Anesthesiology, Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
    Background: Oscillations of the arterial partial pressure of oxygen induced by varying shunt fractions occur during cyclic alveolar recruitment within the injured lung. Recently, these were proposed as a pathomechanism that may be relevant for remote organ injury following acute respiratory distress syndrome. This study examines the transmission of oxygen oscillations to the renal tissue and their tidal volume dependency. Read More

    Case report: anaesthetic management of radical gastrectomy for gastric cancer associated with anti-N-methyl-D-aspartate receptor encephalitis.
    BMC Anesthesiol 2017 Jul 6;17(1):90. Epub 2017 Jul 6.
    Key laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Anaesthesiology, Peking University Cancer Hospital & Institute, Beijing, 100142, China.
    Background: Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a rare neurological disorder that is caused by the production of antibodies against NMDARs. As many anaesthetic drugs interact with NMDARs and may worsen the disease and because the disease poses risks, such as cardiovascular events, hyperthermia and respiratory insufficiency, while under anaesthesia, administering anaesthesia to patients with this disorder is clinically challenging.

    Case Presentation: A 55-year-old man with gastric cancer associated with anti-NMDAR encephalitis who was diagnosed 8 months prior was admitted to Peking University Cancer Hospital for tumour resection. Read More

    Bilateral thoracic Paravertebral block for immediate postoperative pain relief in the PACU: a prospective, observational study.
    BMC Anesthesiol 2017 Jul 5;17(1):89. Epub 2017 Jul 5.
    Department of Anesthesiology, West China Hospital, Sichuan University, No37 Guoxue Street, Chengdu, Sichuan, 610041, People's Republic of China.
    Background: To investigate the feasibility, effectiveness and safety of bilateral thoracic paravertebral block (TPVB) in the post anesthesia care unit (PACU) for pain relief in participants after laparotomy.

    Methods: A single shot of bilateral TPVB with 25 ml of 0.2% ropivacaine and 5 mg dexamethasone in combination for both sides at the 8th thoracic transverse level (T8) was performed on 201 participants who complained moderate to severe pain on arrival to PACU after laparotomy. Read More

    General vs. neuraxial anaesthesia in hip fracture patients: a systematic review and meta-analysis.
    BMC Anesthesiol 2017 Jun 28;17(1):87. Epub 2017 Jun 28.
    Department of Anaesthesiology, University Hospital RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Germany.
    Background: Hip fracture is a trauma of the elderly. The worldwide number of patients in need of surgery after hip fracture will increase in the coming years. The 30-day mortality ranges between 4 and 14%. Read More

    Effects of combined spinal epidural labor analgesia on episiotomy: a retrospective cohort study.
    BMC Anesthesiol 2017 Jun 28;17(1):88. Epub 2017 Jun 28.
    Department of Anesthesiology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, 710061, China.
    Background: According to some published studies, neuraxial analgesia may be associated with prolonged labor and an increased risk for instrumental vaginal delivery. However, its effects on episiotomy are unknown. This study aimed to examine the incidence of episiotomy with and without combined spinal-epidural analgesia (CSEA) during labor. Read More

    Surgical anesthesia with a combination of T12 paravertebral block and lumbar plexus, sacral plexus block for hip replacement in ankylosing spondylitis: CARE-compliant 4 case reports.
    BMC Anesthesiol 2017 Jun 26;17(1):86. Epub 2017 Jun 26.
    Department of anesthesiology and Pain medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Road, Wuhan, 430030, People's Republic of China.
    Background: Anesthesia management for patients with severe ankylosing spondylitis scheduled for total hip arthroplasty is challenging due to a potential difficult airway and difficult neuraxial block. We report 4 cases with ankylosing spondylitis successfully managed with a combination of lumbar plexus, sacral plexus and T12 paravertebral block.

    Case Presentation: Four patients were scheduled for total hip arthroplasty. Read More

    Gabapentin in procedure-specific postoperative pain management - preplanned subgroup analyses from a systematic review with meta-analyses and trial sequential analyses.
    BMC Anesthesiol 2017 Jun 21;17(1):85. Epub 2017 Jun 21.
    Department of Anaesthesiology and Intensive Care, Bispebjerg and Frederiksberg Hospitals, Bispebjerg bakke 23, 2400, Copenhagen, NV, Denmark.
    Background: It has been argued that postoperative pain treatment should be "procedure-specific", since different analgesics may have specific effects dependent on the surgical procedure. The aim of the present subgroup analysis was to compare the beneficial and harmful effects of perioperative gabapentin treatment in different surgical procedures.

    Methods: Relevant databases were searched for randomized clinical trials (RCTs) comparing gabapentin versus placebo. Read More

    Risk factors for pulmonary complications after hepatic resection: role of intraoperative hemodynamic instability and hepatic ischemia.
    BMC Anesthesiol 2017 Jun 20;17(1):84. Epub 2017 Jun 20.
    Department of Anesthesiology and Reanimation, Assistance Publique-Hôpitaux de Paris (AP-HP), University Hospitals Pitié-Salpêtrière Charles-Foix, 43-87 Boulevard de l'Hôpital, 75013, Paris, France.
    Background: Postoperative operative pulmonary complications (PPCs) after hepatic surgery are associated with increased length of hospital stays. Intraoperative blood transfusion, extensive resection and different comorbidities have been identified. Other parameters, like time of hepatic ischemia, have neither been clinically studied, though experimental studies show that hepatic ischemia can provide lung injury. Read More

    Lipid emulsion mitigates impaired pulmonary function induced by limb ischemia/reperfusion in rats through attenuation of local cellular injury and the subsequent systemic inflammatory.
    BMC Anesthesiol 2017 Jun 19;17(1):83. Epub 2017 Jun 19.
    Department of Anesthesiology, the First Affiliated Hospital of Wenzhou Medical University, Zhejiang, China.
    Background: Limb ischemia/reperfusion causes inflammation and elicits oxidative stress that may lead to local tissue damage and remote organ such as lung injury. This study investigates pulmonary function after limb ischemia/reperfusion and the protective effect of a lipid emulsion (Intralipid).

    Methods: Twenty-four rats were divided into three groups: sham operation group (group S), ischemia/reperfusion group (group IR), and lipid emulsion treatment group (group LE). Read More

    Systolic blood pressure variability in patients with early severe sepsis or septic shock: a prospective cohort study.
    BMC Anesthesiol 2017 Jun 17;17(1):82. Epub 2017 Jun 17.
    Pulmonary and Critical Care, Intermountain Medical Center, 5121 Cottonwood St, Murray, UT, 84107, USA.
    Background: Severe sepsis and septic shock are often lethal syndromes, in which the autonomic nervous system may fail to maintain adequate blood pressure. Heart rate variability has been associated with outcomes in sepsis. Whether systolic blood pressure (SBP) variability is associated with clinical outcomes in septic patients is unknown. Read More

    Two-minute disconnection technique with a double-lumen tube to speed the collapse of the non-ventilated lung for one-lung ventilation in thoracoscopic surgery.
    BMC Anesthesiol 2017 Jun 15;17(1):80. Epub 2017 Jun 15.
    Department of Anesthesiology of Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, 200030, China.
    Background: Thoracic surgery requires the effective collapse of the non-ventilated lung. In the majority of cases, we accomplished, accelerated lung collapse using a double-lumen tube (DLT). We hypothesized that using the two-minute disconnection technique with a DLT would improve lung collapse during subsequent one-lung ventilation. Read More

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