Effects of dexmedetomidine on TNF-α and interleukin-2 in serum of rats with severe craniocerebral injury.
BMC Anesthesiol 2017 Sep 20;17(1):130. Epub 2017 Sep 20.
Department of Anesthesiology II, Affiliated Zhongshan Hospital of Dalian University, No. 6 of Jiefang Street, Zhongshan District, Dalian, 116001, China.
Background: Dexmedetomidine is a highly selective adrenergic receptor agonist, which has a dose-dependent sedative hypnotic effect. Furthermore, it also has pharmacological properties, and the ability to inhibit sympathetic activity and improve cardiovascular stability during an operation. However, its protective effect on patients with severe craniocerebral injury in the perioperative period remains unclear. Read More