20,728 results match your criteria BJU international[Journal]


Factors influencing return for maintenance treatment with Percutaneous Tibial Nerve Stimulation for the management of the overactive bladder.

BJU Int 2018 Dec 15. Epub 2018 Dec 15.

Department of Uro-Neurology, The National Hospital for Neurology and Neurosurgery, and UCL Institute of Neurology, Queen Square, London, WC1N 3BG, United Kingdom.

Objectives: To identify factors influencing return for maintenance Percutaneous tibial nerve stimulation (PTNS) treatment after successful completion of a 12-week course of treatment for the overactive bladder (OAB).

Patients And Methods: Patients with OAB symptoms referred for PTNS treatment underwent twelve sessions of weekly PTNS treatment and evaluated at baseline and week 12 using the International Consultation on Incontinence Questionnaire on OAB (ICIQ-OAB), lower urinary tract symptoms related quality of life questionnaire (ICIQ-LUT symptoms QOL) and bladder diary (BD). Responders to treatment, evaluated using two patient-reported outcome measurements, were invited to return for maintenance treatments when symptoms returned. Read More

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December 2018

Functional and Molecular Characterization of the Bilateral Pelvic Nerve Crush Injury Rat Model for Neurogenic Detrusor Underactivity.

BJU Int 2018 Dec 14. Epub 2018 Dec 14.

Laboratory of Experimental Urology, Department of Development and Regeneration, KU Leuven, Leuven, Belgium.

Objectives: To create a rat model for neurogenic detrusor underactivity (DU) by bilateral pelvic nerve crush injury (BPNI) and to study temporal changes in detrusor contractility and morphology.

Methods: Male Sprague-Dawley rats were subjected to BPNI or sham surgery and evaluated 1, 3 and 9 weeks after surgery. Bladder function was determined in vivo by awake cystometry, micturition pattern analysis and 24-hours urine collection. Read More

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December 2018

Urothelial cancer: a narrative review of the role of novel immuno-therapeutic agents with particular reference to the management of non- muscle invasive disease.

BJU Int 2018 Dec 7. Epub 2018 Dec 7.

Department of Oncology, Oxford Cancer and Haematology Centre, Oxford University Hospitals NHS Foundation Trust, Oxford.

Adjuvant intravesical BCG immunotherapy has been the mainstay of treatment for high risk Non Muscle Invasive Bladder Cancer (NMIBC) for decades but is associated with both significant side effect profile and failure rate. Recently, a significant body of trial data has been published demonstrating the successful use of systemic immunotherapy in the treatment of advanced urothelial malignancy and in particular a class of drugs known as "immune checkpoint inhibitors". This has led to the approval of a number of these drugs by the UK National Institute of Clinical Excellence and the US Food and Drug Administration, and ongoing trials are examining use in the management of NMIBC. Read More

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December 2018

An NCDB-based Nomogram to Predict Lymph Node Metastasis in Penile Cancer.

BJU Int 2018 Dec 11. Epub 2018 Dec 11.

Department of Urology, Wake Forest Baptist Health, Winston-Salem, North Carolina.

Introduction: To evaluate the predictive nature of several clinicopathologic variables by developing a nomogram predictive for lymph node positive disease using the National Cancer Database cohort of patients with squamous cell carcinoma of the penis.

Methods: Stepwise logistic regression was utilized to find best-fit model; remaining clinical variables were used to create a nomogram to predict probability of lymph node positive disease.

Results: Upon multivariate analysis, high pathologic grade [(3-4 vs 1 OR 3. Read More

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December 2018

In utero myelomeningocele repair and urological outcome: the first 100 cases of a prospective analysis. Is there an improvement in bladder function?

BJU Int 2018 Dec 9. Epub 2018 Dec 9.

Department of Urology, CACAU-NUPEP, São Paulo, Brazil.

Objectives: To evaluate the first one hundred cases of in utero myelomeningocele repair and urological outcome in a prospective analysis aiming to define possible improvement in bladder function.

Patients And Methods: We used a protocol consisting of detailed medical history, urinary tract ultrasound (US), voiding cystourethrography (VCUG) and urodynamic evaluation (UE). Patients were categorized into 4 patterns, including: normal, high risk (overactive bladder with detrusor leak point pressure higher than 40 cm H2O and high filling pressures also above 40 cm H2O), incontinent and underactivity (underactive bladder with post-void residual urine) and patients were treated accordingly. Read More

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December 2018

Laparoscopic artificial urinary sphincter implantation in women with stress urinary incontinence: update on 13 years experience in a single center.

BJU Int 2018 Dec 11. Epub 2018 Dec 11.

Clinique du Pré, Dept of Urology, Technopôle Université, 13 Avenue René Laennec, 72018, Le Mans, France.

Introduction: Stress urinary incontinence (SUI) mainly affects women as a result of pregnancies with laborious delivery, obesity, and pelvic floor dysfunctions. The first therapeutic approach includes life-style interventions, pelvic floor muscle or bladder training. The second-line treatment usually is surgical. Read More

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December 2018

Bladder mapping of tumor recurrence after radical nephroureterectomy for upper tract urothelial carcinoma and its influence on oncologic outcomes.

BJU Int 2018 Dec 11. Epub 2018 Dec 11.

Sorbonne Université, GRC n°5, ONCOTYPE-URO, AP-HP, Hôpital Pitié-Salpêtrière, F-75013, Paris, France.

Objectives: To assess the location of intravesical recurrence (IVR) after radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC), to determine the main predictive factors for IVR in the bladder cuff area, and to assess the effect of bladder cuff recurrence on prognosis.

Patients And Methods: This was a multicenter, retrospective study using the French collaborative database on UTUC, which includes data for all patients treated in 24 referral uro-oncology centers across the country. All patients undergoing RNU with bladder cuff excision and who developed IVR between 1995 and 2010 were selected. Read More

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December 2018

Guidelines for reporting of statistics for clinical research in urology.

BJU Int 2018 Dec 8. Epub 2018 Dec 8.

Memorial Sloan Kettering Cancer Center.

In an effort to improve the quality of statistics in the clinical urology literature, statisticians at European Urology, The Journal of Urology, Urology and BJUI came together to develop a set of guidelines to address common errors of statistical analysis, reporting and interpretation. Authors should "break any of the guidelines if it makes scientific sense to do so" but would need to provide a clear justification. Adoption of the guidelines will in our view not only increase the quality of published papers in our journals but improve statistical knowledge in our field in general. Read More

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December 2018
3 Reads

Sacral neuromodulation: standardized tined lead implantation technique: two-year clinical outcome and sensory response upon lead stimulation comparing the use of the curved versus straight stylet.

BJU Int 2018 Dec 11. Epub 2018 Dec 11.

Department of Urology, Antwerp University Hospital, Edegem, Belgium.

Objectives: To assess clinical follow-up data over 24 months using the standardized tined lead implantation technique, comparing the use of the curved vs straight stylet.

Patients And Methods: Single tertiary center, prospective study (August 2013 - June 2015) involving 40 patients with overactive bladder and 15 with non-obstructive urinary retention refractory to first-line treatment.

Primary Outcome: successful tined lead procedure; intention to treat analysis at 12 and 24 months. Read More

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December 2018

Comparison of testis cancer-specific survival: an analysis of national cancer registry data from the USA, UK and Germany.

BJU Int 2018 Dec 9. Epub 2018 Dec 9.

Division of Urological Surgery and Center for Surgery and Public Health, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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December 2018

Voxel-wise correlation of PET/CT with multiparametric MRI and histology of the prostate using a sophisticated registration framework.

BJU Int 2018 Dec 10. Epub 2018 Dec 10.

School of Physics, The University of Sydney, Sydney, New South Wales, Australia.

Objectives: To develop a registration framework for correlating positron emission tomography/computed tomography (PET/CT) images with multiparametric MRI (mpMRI) and histology of the prostate, thereby enabling voxel-wise analysis of imaging parameters.

Patients And Methods: In this prospective proof-of-concept study, nine patients scheduled for radical prostatectomy underwent mpMRI and PET/CT imaging prior to surgery. One had PET imaging using F-fluoromethylcholine (FCH), five using Ga-labelled prostate-specific membrane antigen (PSMA)-HBED-CC (PMSA-11) and three using a trial Ga-labelled THP-PSMA tracer. Read More

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December 2018
2 Reads

Simvastatin and the Rho-kinase inhibitor Y-27632 prevent myofibroblast transformation in Peyronie's disease-derived fibroblasts via inhibition of YAP/TAZ nuclear translocation.

BJU Int 2018 Dec 9. Epub 2018 Dec 9.

Laboratory of Experimental Urology, Department of Development and Regeneration, KU, Leuven, Belgium.

Objectives: To uncover the anti-myofibroblast (MFB) properties of Rho-kinase inhibitor (compound Y-27632) and simvastatin in an in vitro model of Peyronie's disease (PD). PD is a sexual debilitating disease caused by an irreversible fibrotic plaque in the penile tunica albuginea (TA). Treatment is limited to surgically restoring anatomical shape. Read More

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December 2018

Phenotypes of Circulating Tumor Cells Predict Time to Castration Resistance in Metastatic Castration-Sensitive Prostate Cancer.

BJU Int 2018 Dec 7. Epub 2018 Dec 7.

Department of Urology, Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China.

Objectives: To identify biomarkers that predict the response to standard androgen deprivation therapy (ADT) of patients newly diagnosed with metastatic castration-sensitive prostate cancer (CSPC) to improve therapeutic decision-making. We investigated whether the characterization of baseline circulating tumor cells (CTCs) predicted the effective period of standard ADT.

Materials And Methods: The study included 108 patients newly diagnosed with high-volume metastatic CSPC. Read More

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December 2018

The duration of infertility affects semen parameters in primary infertile men: results of a single-centre, cross-sectional study.

BJU Int 2018 Dec 4. Epub 2018 Dec 4.

Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy.

Objective: To assess the relationship between the duration of infertility (DI) and the seminal parameters of a cohort of White-European primary infertile men.

Patients And Methods: Data from 1644 infertile men were analysed. Patients were grouped according to the self-reported DI into 12-month time frames. Read More

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December 2018
2 Reads

Outcome Prediction of Prostatic Artery Embolization (PAE): Post hoc analysis of a randomized, open label, non-inferiority trial.

BJU Int 2018 Nov 30. Epub 2018 Nov 30.

Department of Radiology and Nuclear Medicine, St Gallen Cantonal Hospital, St Gallen, Switzerland.

Objectives: To identify predictive parameters of different treatment outcomes after prostatic artery embolization (PAE) in the treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia.

Patients And Methods: A post-hoc analysis of data derived from the 48 patients undergoing PAE in a randomized, open label, non-inferiority trial was performed. Relative changes in the International Prostate Symptoms Score (IPSS), absolute changes in maximum flow rate, and relative changes in MRI-assessed prostate volume from baseline to 12 weeks were defined as the outcomes measures of interest. Read More

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November 2018
1 Read

Examining the relationship between complications and perioperative mortality following radical cystectomy: A population-based analysis.

BJU Int 2018 Nov 30. Epub 2018 Nov 30.

Division of Urology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

Objective: To examine the incidence of perioperative complications after RC and assess their impact on 90-day postoperative mortality during the index stay and upon readmission.

Material And Methods: A total of 57,553 bladder cancer patients (unweighted cohort: 9,137 patients) treated with RC at 360 hospitals in the United States between 2005 to 2013 within the Premier Healthcare Database were used for analysis. Ninety-day perioperative mortality was the primary outcomes. Read More

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November 2018

Using prognosis to guide early detection and treatment selection in non-metastatic prostate cancer.

BJU Int 2018 Nov 30. Epub 2018 Nov 30.

Translational Prostate Cancer Group, CRUK Cambridge Cancer Centre, Cambridge, United Kingdom.

Over recent years there has been an increasing awareness that our ideas on the lethality of primary non-metastatic prostate cancer may need to change. This concept has emerged from a number of different sources including randomised controlled trials, reports from mature active surveillance programmes and prognostic modelling work in large populations (1-2). The evidence suggests that for many men without metastatic disease (85% of all presentations from the recent UK National Prostate Cancer Audit) tumours will evolve slowly and will not translate into cancer related mortality, at least, not within the first 10-15 years of its natural history. Read More

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November 2018

Robot-Assisted Surgery for Benign Distal Ureteral Strictures: Step-by-Step Technique Using the SP Surgical System.

BJU Int 2018 Nov 30. Epub 2018 Nov 30.

Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.

Objectives: To describe the step-by-step techniques for robotic ureteral reimplantation performed by using the Vinci SP surgical system (Intuitive Surgical, Sunnyvale, CA). Different case-scenarios were included with an educational purpose.

Materials And Methods: Three consecutive patients diagnosed with distal benign ureteral strictures were counseled for ureteral reimplantation and accepted to undergo surgery performed by using the da Vinci SP surgical system. Read More

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November 2018
9 Reads

The Onuf's nucleus, serotonin and spinal cord injury.

BJU Int 2018 Nov 30. Epub 2018 Nov 30.

Department of Uro-Neurology, The National Hospital for Neurology and Neurosurgery and UCL Queen Square Institute of Neurology, London, United Kingdom.

Nerve fibres innervating the urethral and anal striated sphincters play an important role in the regulation of urinary and defaecatory continence. These fibres are derived from a group of neurons in the sacral spinal cord known as the Onuf's nucleus. Different neuron groups innervate the anal and urethral sphincter, and the nucleus uniquely demonstrates sexual dimorphism across different species. Read More

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November 2018
1 Read

Long-Term Therapeutic Effect of Cell Therapy on Improvement in Erectile Function in a Rat Model with Pelvic Neurovascular Injury.

BJU Int 2018 Nov 30. Epub 2018 Nov 30.

Wake Forest Institute for Regenerative Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, 27101, USA.

Objective: To determine the long-term therapeutic effect among three types of human cell types on erectile function recovery in a rodent model of dual neurovascular injured erectile dysfunction (NVED).

Materials And Methods: A dual NVED model was established in athymic rats by crushing the bilateral cavernous nerves and ligations of the bilateral internal pudendal nerve-vessel bundles. At the time of defect creation, three different types of human cell populations (2. Read More

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November 2018
1 Read
3.533 Impact Factor

Drowning in ethics for low-risk data: is this best for patients?

BJU Int 2018 Nov;122 Suppl 5

Department of Surgery, Austin Hospital and Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, Vic., Australia.

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November 2018
4 Reads

A picture is worth a thousand words… but does it add utility to a nomogram to predict extraprostatic extension?

Authors:
Caroline M Moore

BJU Int 2018 Dec;122(6):915-916

Reader in Urology, University College London, London, UK.

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December 2018

Science, technology and artificial intelligence.

Authors:
Prokar Dasgupta

BJU Int 2018 Dec;122(6):913

Medical Research Council (MRC) Centre for Transplantation, National Institute for Health Research (NIHR) Biomedical Research Centre, King's College London, London, UK.

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December 2018

Urinary incontinence and the causality dilemma.

BJU Int 2018 Dec;122(6):918-919

Department of Urology, Vanderbilt University, Nashville, TN, USA.

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December 2018

Predicting progression in T1 non-muscle-invasive bladder cancer: back to histology.

BJU Int 2018 Dec;122(6):914-915

Department of Diagnostics and Public Health, University of Verona, Verona, Italy.

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December 2018
3 Reads

Mental imagery: 'You can observe a lot by watching!'

BJU Int 2018 Dec;122(6):920-921

Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.

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December 2018

Ureteroscopy vs miniaturized percutaneous nephrolithotomy: what and who are we comparing?

BJU Int 2018 Dec;122(6):919-920

Service d'Urologie, AP-HP, Hôpital Tenon, Sorbonne Université, Paris, France.

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December 2018

A novel nomogram for predicting ECE of prostate cancer.

BJU Int 2018 Dec;122(6):916-918

Department of Urology, University of Modena and Reggio Emilia, Italy.

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December 2018

First-line checkpoint inhibitors in PD-L1-positive patients with advanced urothelial carcinoma.

BJU Int 2018 Nov 20. Epub 2018 Nov 20.

Russian Society of Clinical Oncology, Moscow, Russia.

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November 2018
4 Reads

Impact of ureteral stent removal by string on patient's quality of life and complications at post-ureteroscopy for urolithiasis: a controlled trial.

BJU Int 2018 Nov 16. Epub 2018 Nov 16.

Department of Urology and Andrology, Kansai Medical University, Osaka, Japan.

Objectives: To evaluate the impact of ureteral stent removal by string in comparison with stent removal by cystoscope regarding with the pain at ureteral stent removal, complications, and quality of life as well as self-rated symptoms of patients after ureteroscopy for urolithiasis.

Patients And Methods: Of 328 patients who underwent ureteroscopy for upper urinary tract stones at our institution, 149 were randomly divided into a ureteral stent removal by string (string group) and by flexible cystoscope (cystoscope group) using gender as a stratification factor. We focused on four sites, namely upper abdomen, bladder, flank, and urethra, to evaluate the most painful site at stent removal. Read More

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November 2018
2 Reads

The Performance Improvement (Pi) score: an algorithm to objectively score performance improvement during E-BLUS hands on training (HoT) sessions. An ESUT project.

BJU Int 2018 Nov 15. Epub 2018 Nov 15.

ICVS/3B's, PT Government Associate Laboratory, Braga/Guimarães, Portugal.

Introduction And Objectives: Assessing performance improvement (Pi) is one of the most important roles of a tutor, but is usually based on subjective observation, personal judgement and expertise. Our study is aimed to evaluate the variability of subjective tutor Pi assessment and to compare it to a novel measurement algorithm: 'the Pi-score' MATERIALS AND METHODS: The Pi-score algorithm considers time measurement and number of errors from two different repetitions (first and fifth) of the same training task and compares them to the relative task goals, to produce an objective score. We collected data during 8 courses on the four basic laparoscopic urological skills (E-BLUS) tasks. Read More

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November 2018

Initial outcomes of local anaesthetic freehand transperineal biopsies in the outpatient setting.

BJU Int 2018 Nov 15. Epub 2018 Nov 15.

Department of Urology, Guy's at St Thomas' Hospitals, London, UK.

Introduction: Systematic transperineal (TP) and targeted prostate biopsies can be achieved using a freehand access system through perineal punctures, with the potential for reduced morbidity and enabling the procedure under local anesthesia (LA), particularly sepsis.

Objectives: To evaluate the histopathological outcomes, morbidity and tolerability of freehand TP prostate biopsies using the PrecisionPoint access system under local anaesthetic (LA) in the day surgery and outpatient environments.

Methods: 176 patients underwent freehand TP prostate biopsies from May 2016 to November 2017. Read More

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November 2018
4 Reads
3.530 Impact Factor

Good clinical practice can and must include comparative effectiveness research.

BJU Int 2018 Nov 13;122 Suppl 5:7-8. Epub 2018 Nov 13.

University of Otago, Christchurch, New Zealand.

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November 2018

Sentinel Node Biopsy in Clinical Stage I Testicular Cancer Enables Early Detection of Occult Metastatic Disease.

BJU Int 2018 Nov 11. Epub 2018 Nov 11.

Department of Oncological Urology, UMC Utrecht Cancer Center, University Medical Center Utrecht, Utrecht, The Netherlands.

Objectives: To report the long-term results of the sentinel node approach in clinical stage I testicular tumour patients in our facility.

Patients And Methods: Analysis of 27 consecutive patients suspected of clinical stage I testicular germ cell tumour and treated with a sentinel node procedure at our tertiary referral centre. Sentinel nodes were identified using lymphoscintigraphy with or without single photo emission computed tomography with computed tomography. Read More

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November 2018
6 Reads

A clinical prediction tool to determine the need for concurrent systematic sampling at the time of magnetic resonance imaging-guided biopsy.

BJU Int 2018 Nov 11. Epub 2018 Nov 11.

Department of Urology, University of Minnesota, Minneapolis, MN, USA.

Objective: To develop a clinical prediction tool that characterises the risk of missing significant prostate cancer by omitting systematic biopsy in men undergoing transrectal ultrasonography/magnetic resonance imaging (TRUS/MRI)-fusion-guided biopsy.

Patients And Methods: A consecutive sample of men undergoing TRUS/MRI-fusion-guided biopsy with the UroNav® system (Invivo International, Best, The Netherlands) who also underwent concurrent systematic biopsy was included. By comparing the grade of cancer diagnosed on targeted and systematic biopsy cores, we identified cases where clinically significant disease (Gleason score ≥3+4) was only found on systematic and not targeted cores. Read More

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November 2018
4 Reads

The ultrasound characteristics of regions identified as suspicious by magnetic resonance imaging (MRI) predict the likelihood of clinically significant cancer on MRI-ultrasound fusion-targeted biopsy.

BJU Int 2018 Nov 11. Epub 2018 Nov 11.

Department of Urology and Radiology, NYU Langone Health, New York, NY, USA.

Objective: To determine whether the presence of an ultrasound hypoechoic region at the site of a region of interest (ROI) on magnetic resonance imaging (MRI) results in improved prostate cancer (PCa) detection and predicts clinically significant PCa on MRI-ultrasonography fusion-targeted prostate biopsy (MRF-TB).

Materials And Methods: Between July 2011 and June 2017, 1058 men who underwent MRF-TB, with or without systematic biopsy, by a single surgeon were prospectively entered into an institutional review board-approved database. Each MRI ROI was identified and scored for suspicion by a single radiologist, and was prospectively evaluated for presence of a hypoechoic region at the site by the surgeon and graded as 0, 1 or 2, representing none, a poorly demarcated ROI-HyR, or a well demarcated ROI-HyR, respectively. Read More

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November 2018

Metabolic consequences of gonadotropin-releasing hormone agonists vs orchiectomy: a randomized clinical study.

BJU Int 2018 Nov 2. Epub 2018 Nov 2.

Department of Urology, Herlev and Gentofte Hospital, Herlev, Denmark.

Objectives: To compare the metabolic changes between men with advanced prostate cancer commenced on a gonadotropin-releasing hormone (GnRH) agonist and those treated with orchiectomy.

Patients And Methods: Fifty-eight hormone-naive men with advanced prostate cancer were randomly assigned (1:1) to either subcapsular orchiectomy or triptorelin 22.5 mg/24 week depot injections. Read More

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November 2018
2 Reads

Prevalence of penile curvature: a population-based cross-sectional study in metropolitan and rural cities in Australia.

BJU Int 2018 Nov;122 Suppl 5:42-49

Department of Urology, Western Health, Melbourne, Vic., Australia.

Objective: To evaluate the prevalence of penile curvature and health-seeking behaviour in Australian men.

Patients And Methods: A population-based, cross-sectional anonymous web-based survey was designed, and men aged between 35 and 75 years in major and rural metropolitan cities across Australia were invited to participate. Respondents were screened for self-reported symptoms of penile curvature and their impact on various psychosexual domains. Read More

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November 2018
1 Read
3.533 Impact Factor

Second-generation of temporary implantable nitinol device for the relief of lower urinary tract symptoms due to benign prostatic hyperplasia: results of a prospective, multicentre study at 1 year of follow-up.

BJU Int 2018 Nov 1. Epub 2018 Nov 1.

Division of Urology, Frimley Health, London, UK.

Objectives: To report the clinical experience with a second-generation of temporary implantable nitinol device (iTIND; Medi-Tate Ltd, Or-Akiva, Israel) for the treatment of lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH) after 1 year of follow-up.

Patients And Methods: In all, 81 patients with LUTS, International Prostate Symptom Score (IPSS) ≥10, maximum urinary flow rate (Q ) ≤12 mL/s, and prostate volume <75 mL, were enrolled in this prospective Research Ethics Committee-approved multicentre study. The main exclusion criteria were: haemostatic disorders, post-void residual urine volume (PVR) >250 mL, obstructive median lobe, and previous prostate surgery. Read More

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November 2018
1 Read

Penile length is preserved after implant surgery.

BJU Int 2018 Oct 30. Epub 2018 Oct 30.

King's College, London, UK.

Objective: To investigate if there is a correlation between penile size measured preoperatively and erect penis after penile implant surgery (PI). A common cause of patient dissatisfaction after PI is caused by patients complaining that surgery has shortened the penis. It has been suggested that stretched penile length preoperatively is almost the same after surgery when the prosthesis is in erect status. Read More

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October 2018
4 Reads

Vaccines for the prevention of recurrent urinary tract infections:A systematic review.

BJU Int 2018 Oct 30. Epub 2018 Oct 30.

Department of Urology, Queen Elizabeth Hospital, Woolwich, London, UK.

Objectives: To systematically review the evidence regarding the efficacy of vaccines or immunostimulants in reducing the recurrence rate of urinary tract infections (UTIs).

Material And Methods: MEDLINE, EMBASE, PubMed, Cochrane Library, WHO International Clinical Trials Registry Platform Search Portal, and conference abstracts were searched up to January2018 for English-titled citations. Randomised placebo-controlled trials evaluating UTI recurrence rates in adult patients with recurrent UTIs treated with a vaccine were selected by two independent reviewers according to the population, interventions, comparators, and outcomes (PICO) criteria. Read More

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October 2018

Prostate cancer heterogeneity: texture analysis score based on multiple MRI sequences for detection, stratification and selection of lesions at time of biopsy.

BJU Int 2018 Oct 30. Epub 2018 Oct 30.

Normandie Univ, UNICAEN, CEA, CNRS, ISTCT/ CERVOxy group, GIP CYCERON, 14000, Caen, France.

Purpose: To undertake an early proof of concept study on a novel, semi-automated texture-based scoring system in order to enhance the association between MRI lesions and clinically significant cancer.

Patients And Methods: With ethics approval, 536 imaging volumes were generated from 20 consecutive patients who underwent mpMRI at time of biopsy. Volumes of interest (VOIs) included zonal anatomy segmentation and suspicious MRI lesion for cancer (Likert scale score greater than 2). Read More

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October 2018
1 Read

The trajectory of patients who die from metastatic prostate cancer: a population-based study.

BJU Int 2018 Oct 29. Epub 2018 Oct 29.

Department of Medicine, St Vincent's Hospital, University of Melbourne, Melbourne, Vic., Australia.

Objectives: To describe health service use, symptom and survival characteristics in metastatic prostate cancer (mPCa) in order to outline usual care practices and identify future opportunities to improve the quality of care in this patient group.

Patients And Methods: This population cohort study, conducted in Victoria, Australia, used 10 years (2000-2010) of linked hospital discharge, emergency visit, and death registration data, to track patients from their first inpatient admission with mPCa until death. Descriptive statistics on inpatient health service use, symptoms, procedures, survival, and place of death are presented. Read More

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October 2018
3 Reads

Penile cancer information on the internet: a needle in a haystack.

BJU Int 2018 Nov 29;122 Suppl 5:22-26. Epub 2018 Oct 29.

Department of Surgery, Austin Hospital, University of Melbourne, Melbourne, Vic., Australia.

Introduction: Penile cancer is a disease with high morbidity and mortality and is rare in developed countries. In the developing world, the incidence is significantly higher, and accounts for 1-2% of malignant disease in men. Penile cancer is associated with delayed diagnosis, often due to psychological factors. Read More

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November 2018
3 Reads
3.530 Impact Factor

Is postoperative Doppler ultrasonography useful for the early detection of asymptomatic pseudoaneurysm and prevention of haemorrhagic complications after partial nephrectomy?

BJU Int 2018 Nov 29;122 Suppl 5:15-21. Epub 2018 Oct 29.

Department of Radiology, Royal Brisbane and Women's Hospital, Brisbane, Qld, Australia.

Objective: To assess the clinical utility of systematic Doppler ultrasonography (DUS) after robot-assisted partial nephrectomy (PN) for the detection of renal artery pseudoaneurysm (PA) and to allow pre-emptive arterial embolization to reduce the postoperative bleeding risk.

Materials And Methods: A retrospective study was conducted including all consecutive patients treated with robot-assisted PN for renal tumours between 2015 and 2017. Every patient underwent renal DUS in the early postoperative period. Read More

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November 2018
4 Reads

Penile traction therapy with the new device 'Penimaster PRO' is effective and safe in the stable phase of Peyronie's disease: a controlled multicenter study.

BJU Int 2018 Oct 26. Epub 2018 Oct 26.

Rush University Medical Center, Chicago, USA.

Objectives: To evaluate the efficacy and safety of a new penile traction device (PTD) 'Penimaster PRO' in a group of patients with stable Peyronie's disease (PD) compared to a non-intervention group in a multicentre study trial.

Material And Methods: 93 patients with chronic stable PD (without ED, no significant pain, and with a unidirectional curvature of at least 45 degrees being stable for more than 3 months) were recruited and followed for a 12-week period. 47 patients were randomly assigned to 'PeniMaster PRO' group (PG) and 46 assigned to the non-intervention group (NIG). Read More

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October 2018
7 Reads

The opioid epidemic: a wake-up call for us all.

BJU Int 2018 Nov;122(5):719-720

The London Clinic, London W1G 6BW, UK.

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November 2018

Contemporary quality-of-life scores provide a key foundation for high-quality cancer research.

BJU Int 2018 Nov;122(5):720-721

Center for Surgery and Public Health, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.

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November 2018
5 Reads

Multiparametric MRI: an important tool to improve risk stratification for active surveillance in prostate cancer.

BJU Int 2018 Nov;122(5):721-722

Martini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, Hamburg, Germany.

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November 2018
4 Reads