Search our Database of Scientific Publications and Authors

I’m looking for a

    10672 results match your criteria BJU international[Journal]

    1 OF 214

    Prostate Cancer Treatment in Renal Transplant Recipients: A Systematic Review.
    BJU Int 2017 Sep 18. Epub 2017 Sep 18.
    Molinette Hospital - University of Studies of Turin - Italy, Urology.
    Background: The majority of kidney transplants are performed in recipients (RTR) over 50; simultaneously their life expectancy is improving. The increasing age and number of RTR is likely to be paralleled by an increase of prostate cancer (PCa) incidence. However, little is known on the optimal management of these patients who represent a therapeutic challenge due to medical and anatomical graft-related issues. Read More

    First-line therapy with dacomitinib, an orally available pan-HER tyrosine kinase inhibitor, for locally-advanced or metastatic penile squamous cell carcinoma: results of an open label, single-arm, single-center, phase 2 study.
    BJU Int 2017 Sep 16. Epub 2017 Sep 16.
    Department of Surgery Urology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori.
    Objective: To harness the frontline therapy in advanced penile squamous cell carcinoma (PSCC), for which chemotherapy exerts moderate activity but poor efficacy. Dacomitinib is an irreversible, pan-epidermal growth factor receptor (HER) inhibitor.

    Patients And Methods: In a phase 2 study (NCT01728233), patients received dacomitinib 45 mg/day, orally, continuously. Read More

    Prospective comparison of transperineal MRI/ultrasound-fusion biopsy and transrectal systematic biopsy in biopsy-naïve patients.
    BJU Int 2017 Sep 16. Epub 2017 Sep 16.
    Department of Urology, Technische Universität Dresden, Dresden, Germany.
    Objectives: To evaluate the value of multiparametric magnetic resonance imaging (mpMRI) for the detection of significant prostate cancer (PCa) and to compare transperineal MRI/ultrasound-fusion biopsy (fusPbx) to conventional transrectal systematic biopsy (sysPbx) in biopsy-naïve patients.

    Patients And Methods: This multicentre, prospective trial investigated biopsy-naïve patients with suspicion of PCa undergoing transperineal fusPbx in combination with transrectal sysPbx (comPbx). The primary outcome was the detection of significant PCa defined as Gleason pattern four or five. Read More

    Robotic Kidney Transplantation: Comparison of the First 40 Cases of Open vs Robotic Transplantations by a Single Surgeon.
    BJU Int 2017 Sep 16. Epub 2017 Sep 16.
    Department of Nephrology, Bakirkoy Dr. Sadi Konuk Teaching and Research Hospital, Istanbul, Turkey.
    Objective: To compare the outcomes of the first 40 cases who underwent robotic kidney transplantation (RKT) with those of the first 40 cases who underwent open kidney transplantation (KT) in the Dr. Sadi Konuk Training Hospital.

    Material And Methods: Between January 2016 and February 2017, we prospectively collected the data of the first 40 RKT cases (RKT group) and compared them with those of the first 40 open KT cases (OKT group). Read More

    Guideline of Guidelines - Asymptomatic Microscopic Haematuria.
    BJU Int 2017 Sep 16. Epub 2017 Sep 16.
    Department of Urology, Mayo Clinic, Rochester, MN.
    Objective: To review major organizational guidelines on the evaluation and management of asymptomatic microscopic haematuria (AMH).

    Methods: This is a review of the haematuria guidelines from 1.) American Urological Association (AUA), 2. Read More

    Systematic Review and Network Meta-Analysis on the Relative Efficacy of Osteoporotic Medications: Men with Prostate Cancer on Continuous Androgen Deprivation Therapy to Reduce Risk of Fragility Fractures.
    BJU Int 2017 Sep 18. Epub 2017 Sep 18.
    The University of Toronto, Ontario, Canada.
    Background: Androgen deprivation therapy (ADT) is an effective treatment for men with advanced prostate cancer, but loss of bone mineral density (BMD) is a major risk factor for fractures. This analysis evaluated the relative effectiveness of osteoporosis treatments using BMD as a surrogate endpoint for fragility fractures in men on continuous ADT.

    Method: We included randomized controlled trials studying bisphosphonates, denosumab, toremifene, and raloxifene in patients with non-metastatic prostate cancer on ADT for review. Read More

    Perioperative Allogeneic Blood Transfusion Does Not Adversely Impact Oncological Outcomes After Radical Cystectomy for Urinary Bladder Cancer - a Propensity Score-weighted European Multicenter Study.
    BJU Int 2017 Sep 14. Epub 2017 Sep 14.
    Department of Urology, University Medical Center Rostock, Rostock, Germany.
    Objectives: To evaluate the effect of perioperative blood transfusion (PBT) on recurrence-free survival (RFS), overall survival (OS), cancer-specific mortality (CSM), and other-cause mortality (OCM) in patients undergoing radical cystectomy (RC), utilizing a contemporary European multicenter cohort.

    Patients And Methods: The PROspective MulticEnTer RadIcal Cystectomy Series (PROMETRICS) includes data on 679 patients who underwent RC at 18 European tertiary care centers in 2011. The association between PBT and oncological survival outcomes was assessed using Kaplan-Meier, Cox regression, and competing-risks analyses. Read More

    Effects of Thiazolidinedione in Patients with Active Bladder Cancer.
    BJU Int 2017 Sep 5. Epub 2017 Sep 5.
    Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, TX.
    Objective: To examine the influence of perioperative thiazolidinedione (TZD) on cancer-specific outcomes in patients undergoing radical cystectomy (RC) for urothelial carcinoma (UC).

    Design, Setting, And Participants: A retrospective cohort of 173 diabetic patients undergoing RC from 2005 to 2010 was identified. Of those, 53 were on TZD treatment at the time of surgery, with 33 patients taking pioglitazone. Read More

    Prospective Randomized Non-Inferiority Trial of Pelvic Drain Placement Versus No Pelvic Drain Placement after Robot-Assisted Radical Prostatectomy.
    BJU Int 2017 Sep 5. Epub 2017 Sep 5.
    City of Hope National Medical Center, Department of Surgery, Division of Urology and Urologic Oncology, Duarte, CA.
    Objectives: To determine if eliminating the prophylactic placement of a pelvic drain (PD) after robot-assisted radical prostatectomy (RARP) affects the incidence of early (90-day) postoperative adverse events.

    Materials And Methods: In this parallel-group, blinded, non-inferiority trial, we randomized patients planning to undergo RARP to one of two arms: no drain placement (ND) or PD placement. Patients with demonstrable intra-operative leakage upon bladder irrigation were excluded. Read More

    Association between Metabolic Syndrome and intravesical prostatic protrusion in benign prostatic enlargement patients with lower urinary tract symptoms (MIPS Study).
    BJU Int 2017 Sep 5. Epub 2017 Sep 5.
    Urology section, Department of surgery, University of Catania.
    Objective: To investigate the association between metabolic syndrome (MetS) and morphological features of benign prostatic enlargement (BPE), including total prostate volume (TPV), transitional zone volume (TZV) and intra vesical prostatic protrusion (IPP).

    Patients And Methods: From January 2015 to January 2017, 224 consecutive men older than 50 years presenting with lower urinary tract symptoms (LUTS) suggestive of BPE were recruited in this multicentre cross-sectional study. MetS was defined according to international diabetes federation criteria. Read More

    Time on androgen deprivation therapy and adaptations to exercise: secondary analysis from a 12-month randomized controlled trial in men with prostate cancer.
    BJU Int 2017 Sep 5. Epub 2017 Sep 5.
    Exercise Medicine Research Institute, Edith Cowan University, Joondalup, WA, Australia.
    Objectives: To explore if duration of prior exposure to androgen deprivation therapy (ADT) in men with prostate cancer (PCa) undertaking a yearlong exercise program moderates the exercise response on body composition and muscle performance. In addition, we explored the moderator effect of baseline testosterone, time since ADT, and baseline value of the outcome.

    Patients And Methods: In a multicenter randomized controlled trial, 100 patients previously treated for either 6 months (short-term) or 18 months (long-term) ADT in combination with radiotherapy as part of the TROG 03. Read More

    Multi-centre, prospective evaluation of the Seldinger technique for difficult male urethral catheter insertions by non-urology trained doctors.
    BJU Int 2017 Sep 5. Epub 2017 Sep 5.
    Department of Urology, Gosford District Hospital, Gosford, NSW, Australia.
    Objective: To evaluate the safety and effectiveness of the Seldinger technique by non-urology trained (NUT) doctors for difficult male indwelling urinary catheter (IDC) insertions.

    Patients And Methods: In all, 115 patients and 57 participating NUT doctors were recruited by the urologist or urology registrar, when contacted in regards to failed IDC insertion. The successful passage of an IDC by the NUT doctors using the Seldinger technique with a straight, hydrophilic guidewire was assessed in our prospective, multicentre evaluation. Read More

    Feasibility and safety of focal irreversible electroporation as salvage treatment for localized radio-recurrent prostate cancer.
    BJU Int 2017 Aug 21. Epub 2017 Aug 21.
    St Vincent's Prostate Cancer Centre, Darlinghurst, NSW, Australia.
    Objectives: To evaluate the feasibility, safety, early quality-of-life (QoL) and oncological outcomes of salvage focal irreversible electroporation (IRE) for radio-recurrent prostate cancer (PCa).

    Patients And Methods: Patients with localized, radio-recurrent PCa without evidence of metastatic or nodal disease were offered focal IRE according to the consensus guidelines. Patients with a minimum follow-up of 6 months were eligible for analysis. Read More

    Analysis of survival for patients with chronic kidney disease primarily related to renal cancer surgery.
    BJU Int 2017 Aug 21. Epub 2017 Aug 21.
    Glickman Urological and Kidney Institute, Cleveland, OH, USA.
    Objectives: To evaluate predictors of long-term survival for patients with chronic kidney disease primarily due to surgery (CKD-S). Patients with CKD-S have generally good survival that approximates patients who do not have CKD even after renal cancer surgery (RCS), yet there may be heterogeneity within this cohort.

    Patients And Methods: From 1997 to 2008, 4 246 patients underwent RCS at our centre. Read More

    More extended lymph node dissection template at radical prostatectomy detects metastases in the common iliac region and in the fossa of Marcille.
    BJU Int 2017 Aug 21. Epub 2017 Aug 21.
    Department of Urology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
    Objectives: To assess the effect of adding lymph nodes (LNs) located along the common iliac vessels and in the fossa of Marcille to the extended pelvic LN dissection (PLND) template at radical prostatectomy (RP).

    Patients And Methods: A total of 485 patients underwent RP and PLND at a referral centre between 2000 and 2008 (historical cohort: classic extended PLND template) and a total of 268 patients between 2010 and 2015 (contemporary cohort: extended PLND template including LNs located along the common iliac vessels and in the fossa of Marcille). Descriptive analyses were used to compare baseline, pathological, complication and functional data between the two cohorts. Read More

    Does robot-assisted radical prostatectomy benefit patients with prostate cancer and bone oligometastases?
    BJU Int 2017 Aug 21. Epub 2017 Aug 21.
    Department of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul, Korea.
    Objective: To investigate the peri-operative and oncological outcomes of robot-assisted radical prostatectomy (RARP) in patients with oligometastatic prostate cancer (PCa).

    Patients And Methods: We retrospectively reviewed the records of 79 patients with oligometastatic PCa treated with RARP or androgen deprivation therapy (ADT) between 2005 and 2015 at our institution. Of these 79 patients, 38 were treated with RARP and 41 were treated with ADT without local therapy. Read More

    Controlled release of IGF1 enhances urethral sphincter function and histological structure in the treatment of female stress urinary incontinence in a rodent model.
    BJU Int 2017 Aug 14. Epub 2017 Aug 14.
    Institute for Regenerative Medicine, Wake Forest University, Winston-Salem, NC, USA.
    Objectives: Stress urinary incontinence (SUI) diminishes the quality of life of millions, particularly women who have delivered vaginally, which can injure the urethral sphincter. Despite several well-established treatments for SUI, growth factor therapy might provide an alternative to promote urethral sphincter repair. The goal of this study was to determine the effects of controlled release of IGF1 from alginate-poly-L-ornithine-gelatin microbeads (IGF1-A-PLO-G microbeads) on sphincter tissue regeneration in a rat model of SUI. Read More

    Female urethral injuries associated with pelvic fracture: a systematic review of the literature.
    BJU Int 2017 Aug 14. Epub 2017 Aug 14.
    Division of Urology, Department of Surgery, Cedars Sinai Medical Center, Los Angeles, CA, USA.
    To review systematically the literature on female urethral injuries associated with pelvic fracture and to determine the optimum management of this rare injury. Using Meta-analysis of Observational Studies in Epidemiology criteria, we searched the Cochrane, Pubmed and OVID databases for all articles available before 30 June 2016 using the terms 'female pelvic fracture urethroplasty', 'female urethral distraction', 'female pelvic fracture urethral injury' and 'female pelvic fracture urethra girls.' Two authors of this paper independently reviewed the titles, abstracts, and articles in duplicate. Read More

    Multiparametric magnetic resonance imaging identifies significant apical prostate cancers.
    BJU Int 2017 Aug 14. Epub 2017 Aug 14.
    Department of Urology, New York University School of Medicine, New York, NY, USA.
    Objective: To determine if multiparametric (mp) magnetic resonance imaging (MRI) can identify significant apical disease, thereby informing decisions regarding preservation of the membranous urethra.

    Materials And Methods: Men undergoing radical prostatectomy (RP) between January 2012 and June 2016, who underwent a 12-core transrectal ultrasonography-guided systematic biopsy (SB), preoperative 3-Tesla MRI, and sectioning of the prostate specimen with tumour foci mapping, were extracted from a single surgeon's prospective longitudinal outcomes database. Apical SB and mpMRI lesion results were compared with regard to their ability to predict aggressive tumours in the prostatic apex (PA), defined as prostate cancer grade group >1. Read More

    Microvascular and lymphovascular tumour invasion are associated with poor prognosis and metastatic spread in renal cell carcinoma: a validation study in clinical practice.
    BJU Int 2017 Aug 13. Epub 2017 Aug 13.
    Department of Urology, Ernst-Moritz Arndt University of Greifswald, Greifswald, Germany.
    Objective: To validate microvascular (MVI) and lymphovascular (LVI) invasion as prognostic factors in patients with renal cell carcinoma (RCC).

    Patients And Methods: Data of patients with RCC who underwent radical or nephron-sparing surgery were prospectively collected from three academic centres. The occurrence of MVI and LVI was determined with standard staining protocols by experienced pathologists at the time of diagnosis. Read More

    Focal irreversible electroporation as primary treatment for localized prostate cancer.
    BJU Int 2017 Aug 10. Epub 2017 Aug 10.
    St Vincent's Prostate Cancer Centre, Darlinghurst, NSW, Australia.
    Objectives: To determine the safety, quality of life (QoL) and short-term oncological outcomes of primary focal irreversible electroporation (IRE) for the treatment of localized prostate cancer (PCa), and to identify potential risk factors for oncological failure.

    Patients And Methods: Patients who met the consensus guidelines on patient criteria and selection methods for primary focal therapy were eligible for analysis. Focal IRE was performed for organ-confined clinically significant PCa, defined as high-volume disease with Gleason sum score 6 (International Society of Urological Pathology [ISUP] grade 1) or any Gleason sum score of 7 (ISUP grades 2-3). Read More

    Evaluation of a needle disinfectant technique to reduce infection-related hospitalisation after transrectal prostate biopsy.
    BJU Int 2017 Aug 10. Epub 2017 Aug 10.
    Department of Urology, University of Michigan, Ann Arbor, MI, USA.
    Objectives: To determine whether a needle disinfectant step during transrectal ultrasonography (TRUS)-guided prostate biopsy is associated with lower rates of infection-related hospitalisation.

    Patients And Methods: We conducted a retrospective analysis of all TRUS-guided prostate biopsies taken across the Michigan Urological Surgery Improvement Collaborative (MUSIC) from January 2012 to March 2015. Natural variation in technique allowed us to evaluate for differences in infection-related hospitalisations based on whether or not a needle disinfectant technique was used. Read More

    cAMP-dependent post-translational modification of neuronal nitric oxide synthase neuroprotects penile erection in rats.
    BJU Int 2017 Aug 7. Epub 2017 Aug 7.
    The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
    Objectives: To evaluate neuronal nitric oxide (NO) synthase (nNOS) phosphorylation, nNOS uncoupling, and oxidative stress in the penis and major pelvic ganglia (MPG), before and after the administration of the cAMP-dependent protein kinase A (PKA) agonist colforsin in a rat model of bilateral cavernous nerve injury (BCNI),which mimics nerve injury after prostatectomy.

    Materials And Methods: Adult male Sprague-Dawley rats were divided into BCNI and sham-operated groups. Each group included two subgroups: vehicle and colforsin (0. Read More

    Serous-lined, stapled pouch wall plication: initial results of a simple and quick novel continence mechanism in troubleshooting secondary to continent cutaneous urinary diversion.
    BJU Int 2017 Aug 4. Epub 2017 Aug 4.
    Department of Urology and Paediatric Urology, Julius-Maximilians-University Medical School, Würzburg, Germany.
    Objectives: To report a novel and straightforward technique of a secondary continent outlet for continent cutaneous urinary diversion (CCUD) reservoirs without the need for further bowel resection, reducing operating time and length of hospitalization.

    Patients And Methods: From 2015 to 2017, six patients with unreconstructable, incontinent outlets (out of a total pool of 595 patients with CCUD) have undergone the technique described in the present paper at our department. The technique relies on the Mitrofanoff principle, using a stapled full-thickness pouch wall plication, which creates a flap-valve continence mechanism. Read More

    Intradetrusor onabotulinumtoxinA injections for refractory neurogenic detrusor overactivity incontinence: do we need urodynamic investigation for outcome assessment?
    BJU Int 2017 Aug 3. Epub 2017 Aug 3.
    Neuro-Urology, Spinal Cord Injury Center and Research, University of Zürich, Balgrist University Hospital, Zürich, Switzerland.
    Objective: To evaluate if urinary continence in patients with refractory neurogenic detrusor overactivity (NDO) incontinence after intradetrusor onabotulinumtoxinA injections is sufficient for appropriate outcome assessment or if urodynamic investigation (UDI) is needed.

    Patients And Methods: A consecutive series of 148 patients undergoing intradetrusor onabotulinumtoxinA injections for refractory NDO incontinence were prospectively evaluated. Patients underwent UDI before and at 6 weeks after onabotulinumtoxinA injections. Read More

    Comparison of lesions detected and undetected by template-guided transperineal saturation prostate biopsy.
    BJU Int 2017 Aug 3. Epub 2017 Aug 3.
    Department of Urology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
    Objectives: To compare the characteristics of lesions detected or undetected by template-guided transperineal saturation prostate biopsy and to evaluate the potential impact of undetected lesions.

    Materials And Methods: We evaluated the characteristics of lesions in radical prostatectomy (RP) specimens, compared the differences between lesions detected and undetected by systematic transperineal ultrasonography-guided 11-region biopsy with regard to tumour volume, Gleason score, surgical margin, spatial location and clinical significance, and assessed the potential impact of undetected clinically significant lesions.

    Results: The median number of biopsy cores was 24. Read More

    Impact of warm ischaemia time on postoperative renal function after partial nephrectomy for clinical T1 renal cell carcinoma: a propensity score-matched study.
    BJU Int 2017 Jul 27. Epub 2017 Jul 27.
    Department of Urology, Seoul National University Bundang Hospital, Seongnam, Korea.
    Objectives: To analyse the effect of prolonged warm ischaemia time (WIT) on long-term renal function after partial nephrectomy (PN), as controversy still exists as to whether prolonged WIT adversely affects the incidence of chronic kidney disease (CKD) after PN.

    Patients And Methods: We reviewed data from 1816 patients who underwent PN for a clinical T1 renal tumour. The propensity scores for prolonged WIT were calculated with the shorter WIT group (<30 min) matched to the longer WIT group (≥30 min) in a 2:1 ratio. Read More

    Diagnostic accuracy of a five-point Likert scoring system for magnetic resonance imaging (MRI) evaluated according to results of MRI/ultrasonography image-fusion targeted biopsy of the prostate.
    BJU Int 2017 Jul 27. Epub 2017 Jul 27.
    USC Institute of Urology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
    Objective: To evaluate the accuracy of a magnetic resonance imaging (MRI)-based Likert scoring system in the detection of clinically significant prostate cancer (CSPC), using MRI/ultrasonography (US) image-fusion targeted biopsy (FTB) as a reference standard.

    Patients And Methods: We retrospectively reviewed 1218 MRI-detected lesions in 629 patients who underwent subsequent MRI/US FTB between October 2012 and August 2015. 3-Tesla MRI was independently reported by one of eight radiologists with varying levels of experience and scored on a five-point Likert scale. Read More

    'Trifecta' outcomes of robot-assisted partial nephrectomy in solitary kidney: a Vattikuti Collective Quality Initiative (VCQI) database analysis.
    BJU Int 2017 Jul 27. Epub 2017 Jul 27.
    Vattikuti Urology Institute, Henry Ford Hospital, Detroit, MI, USA.
    Objectives: To analyse the outcomes of robot-assisted partial nephrectomy (RAPN) in patients with a solitary kidney in a large multi-institutional database.

    Patients And Methods: In all, 2755 patients in the Vattikuti Collective Quality Initiative database underwent RAPN by 22 surgeons at 14 centres in nine countries. Of these patients, 74 underwent RAPN with a solitary kidney between 2007 and 2016. Read More

    Ventral-onlay buccal mucosa graft substitution urethroplasty for urethral stricture in women.
    BJU Int 2017 Jul 27. Epub 2017 Jul 27.
    Department of Urology, University College London Hospital at Westmoreland Street, London, UK.
    Objective: To present our outcomes of ventral-onlay buccal mucosa graft (BMG) substitution urethroplasty in treating female urethral stricture (FUS).

    Patients And Methods: We conducted a review of a prospectively collected database of 22 consecutive women (median [range] age 50 [34-72] years) with urethral stricture who underwent ventral onlay BMG substitution urethroplasty after June 2012 and who had a minimum follow-up of 6 months (median 21.5, range 6-51 months). Read More

    Comparison between target magnetic resonance imaging (MRI) in-gantry and cognitively directed transperineal or transrectal-guided prostate biopsies for Prostate Imaging-Reporting and Data System (PI-RADS) 3-5 MRI lesions.
    BJU Int 2017 Jul 27. Epub 2017 Jul 27.
    Wesley Hospital, University of Queensland, Brisbane, Qld, Australia.
    Objective: To compare the detection rates of prostate cancer (PCa) in men with Prostate Imaging-Reporting and Data System (PI-RADS) 3-5 abnormalities on 3-Tesla multiparametric (mp) magnetic resonance imaging (MRI) using in-bore MRI-guided biopsy compared with cognitively directed transperineal (cTP) biopsy and transrectal ultrasonography (cTRUS) biopsy.

    Methods: This was a retrospective single-centre study of consecutive men attending the private practice clinic of an experienced urologist performing MRI-guided biopsy and an experienced urologist performing cTP and cTRUS biopsy techniques for PI-RADS 3-5 lesions identified on 3-Tesla mpMRI.

    Results: There were 595 target mpMRI lesions from 482 men with PI-RADS 3-5 regions of interest during 483 episodes of biopsy. Read More

    Large institutional variations in use of androgen deprivation therapy with definitive radiotherapy in a population-based cohort of men with intermediate- and high-risk prostate cancer.
    BJU Int 2017 Jul 27. Epub 2017 Jul 27.
    Alfred Health Radiation Oncology Services, Prahran, Vic., Australia.
    Objective: To evaluate the pattern of use of androgen deprivation therapy (ADT) with definitive radiotherapy (RT) in men with prostate cancer (PCa) in a population-based study in Australia.

    Patients And Methods: This is a prospective cohort of men with intermediate- and high-risk PCa, captured in the population-based Prostate Cancer Outcome Registry Victoria, who were treated with definitive prostate RT between January 2010 and December 2015. The primary outcome of interest was ADT utilization. Read More

    Transumbilical laparoendoscopic single-site radical prostatectomy and cystectomy with the aid of a transurethral port: a feasibility study.
    BJU Int 2017 Jul 22. Epub 2017 Jul 22.
    Department of Urology, Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Jiangsu Provincial Hospital of Traditional Chinese Medicine, Nanjing, China.
    Objective: To describe the surgical technique and report early outcomes of transurethral assisted laparoendoscopic single-site (LESS) radical prostatectomy (RP) and LESS radical cystectomy (RC) in a single institution.

    Materials And Methods: Between December 2014 and March 2016, a total of 114 LESS RPs and RCs were performed, comprising 68 LESS RPs, 38 LESS RCs with cutaneous ureterostomy (CU) and eight LESS RCs with orthotopic ileal neobladder (OIN). Access was achieved via a single-port, with four channels placed through a transumblical incision. Read More

    Implementation rates of uro-oncology multidisciplinary meeting decisions.
    BJU Int 2017 Jul 18. Epub 2017 Jul 18.
    Department of Urology, Austin Health, Heidelberg, Vic., Australia.
    Objectives: To assess implementation rates of the consensus plans made at the uro-oncology multidisciplinary meeting (MDM) of an Australian tertiary centre, and analyse obstacles to implementation.

    Methods: A retrospective review was performed of all patients discussed at the uro-oncology MDM at our institution between 1 January and 30 June 2015. Rates of referral for MDM discussion after a new histological diagnosis of malignancy, categorised by tumour type, were assessed. Read More

    Baseline and longitudinal plasma caveolin-1 level as a biomarker in active surveillance for early-stage prostate cancer.
    BJU Int 2017 Jul 15. Epub 2017 Jul 15.
    Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
    Objectives: To evaluate the role of caveolin-1 (Cav-1) as a predictor of disease reclassification (DR) in men with early prostate cancer undergoing active surveillance (AS).

    Patients And Methods: We analysed archived plasma samples prospectively collected from patients with early prostate cancer in a single-institution AS study. Of 825 patients enrolled, 542 had ≥1 year of follow-up. Read More

    1 OF 214