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Iran J Kidney Dis 2019 Mar;13(2):132-133

University of Health Sciences, Konya Research and Training Hospital, Nephrology Department, Konya, Turkey.

McKittrick-Wheelock syndrome is a rare complication of rectosigmoid villous adenoma leading to secretory diarrhea, prerenal acute kidney injury and severe fluid and electrolyte imbalances. There are about 50 cases reported in literature. We represent a case of 71 year-old patient with persistant chronic diarrhea, prerenal azotemia, severe hypokalemia, and hyponatremia. Read More

Med Pharm Rep 2019 Jan 15;92(1):36-42. Epub 2019 Jan 15.

Internal Medicine Department, Pt. BD Sharma PGIMS, Rohtak, India.

Introduction: Scrub typhus is an acute febrile illness caused by . It is characterised by fever, rash, myalgia and diffuse lymphadenopathy. Most common complications are sepsis, shock, acute respiratory distress syndrome (ARDS), hepatitis, pre renal azotemia and multi organ dysfunction syndrome (MODS). Read More

J Am Vet Med Assoc 2019 Apr;254(8):944-952

Objective: To describe postobstructive diuresis (POD) in cats undergoing surgical placement of ureteral stents or subcutaneous ureteral bypass systems for treatment of ureteral obstruction in cats and to identify factors associated with duration and maximum severity of POD.

Design: Retrospective case series.

Animals: 37 client-owned cats with ureteral obstruction treated between August 2010 and December 2014. Read More

Prog Mol Biol Transl Sci 2019 8;162:349-362. Epub 2019 Mar 8.

Systems Biology and Medicine Center for Complex Diseases, Affiliated Hospital of Qingdao University, Qingdao, China. Electronic address:

Fucosylated glycans are essential molecules that facilitate signal transductions in several signal pathways and play important roles in development, inflammation, infection, and tumor metastasis. The fucosylated glycans are difficult to be developed into clinical biomarkers due to their complicated structures, but the decreased or increased activities of serum α-l-fucosidase, the lysosomal enzyme required for fucosylated glycan degradation, are diagnostic biomarker for patients with fucosidosis and hepatocellular carcinoma, respectively. However, the relationship between serum α-l-fucosidase activities and other human diseases is largely unknown. Read More

Prog Mol Biol Transl Sci 2019 6;162:307-319. Epub 2019 Mar 6.

Systems Biology and Medicine Center for Complex Diseases, Affiliated Hospital of Qingdao University, Qingdao, China. Electronic address:

Serum glycated albumin (GA) level is used along with that of glucose and glycated hemoglobin (HbA1c) as indicators of glycemic control for diabetic patients. Although serum GA levels are affected by blood glucose level, they are also influenced by serum albumin metabolism and other pathological conditions. However, a systematic comparison of the serum GA levels in different types of human diseases has not been reported. Read More

Prog Mol Biol Transl Sci 2019 9;162:165-175. Epub 2019 Mar 9.

Systems Biology and Medicine Center for Complex Diseases, Affiliated Hospital of Qingdao University, Qingdao, China. Electronic address:

Increased serum squamous cell carcinoma antigen (SCCA) levels are clinically used diagnostic or prognostic biomarker for squamous cell carcinomas. According to recently published studies, increased serum SCCA levels are also observed in adenocarcinomas, hepatocarcinomas, kidney, and other inflammatory diseases, indicating squamous cell carcinoma is not the production source of serum SCCA in these diseases. However, serum SCCA levels in patients suffering different types of diseases have not been systematically measured and compared. Read More

Mech Ageing Dev 2019 Mar 14;180:1-10. Epub 2019 Mar 14.

Department of Clinical and Molecular Sciences, DISCLIMO, Università Politecnica delle Marche, Ancona, Italy; Center of Clinical Pathology and Innovative Therapy, IRCCS INRCA, Ancona, Italy.

To evaluate the combined effect of age and glycemic state on circulating levels of the inflamma-miR-146a levels, 188 healthy subjects (CTR) aged 20-104 years and 144 type-2 diabetic patients (T2DM), aged 40-80 years, were analyzed. In CTR subjects, miR-146a levels showed a significant age-related decline. When a gender-stratified analysis was ran, the miR-146a age-related trajectory was confirmed only in men and a negative correlation with PAI-1, uric acid, and creatinine was also observed. Read More

Caspian J Intern Med 2019 ;10(1):11-15

Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

Background: The aim of this study was to use the volume of the graft as an adjunct tool for better decision making.

Methods: Kidney transplanted patients with acute azotemia and documented volume and finally a biopsy were enrolled in this study‌. Graft volumes between rejected patients (antibody-mediated rejection {AMR} and cell - mediated rejection {CMR}) and ‌non rejected but azotemic patients were compared. Read More

J Am Assoc Lab Anim Sci 2019 Mar 7. Epub 2019 Mar 7.

Sustained-release (SR) drugs refine current analgesic regimens by alleviating the need for multiple sessions of handlingand restraint and by reducing the local tissue irritation that can occur due to repeated injections. Although a variety of SRdrugs are already used in lab animal medicine, no studies exist that evaluate the suitability of an SR NSAID in sheep. Thisstudy used HPLC-MS to measure the plasma concentrations of 2 formulations of meloxicam-conventional and SRM-after subcutaneous administration in 6 adult ewes. Read More

Vet J 2019 Mar 17;245:77-81. Epub 2019 Jan 17.

Veterinary Teaching Hospital 'Mario Modenato', Department of Veterinary Sciences, University of Pisa, Via Livornese Lato monte, San Piero a Grado 56122, Pisa, Italy.

Acute pancreatitis and acute kidney injury are well-documented comorbidities in human medicine. Dogs that develop acute kidney injury during hospitalization have significantly higher mortality rates than those that do not. The aim of this study was to evaluate the prevalence of acute kidney injury in dogs with acute pancreatitis and the prognostic value of various clinicopathological parameters. Read More

Intern Med J 2019 Feb 28. Epub 2019 Feb 28.

Department of Nephrology, Prince of Wales Clinical School, University of New South Wales, Sydney, New South Wales, Australia.

Background: Acute kidney injury (AKI) is a rapid deterioration of renal function, often caused by a variety of co-existing morbidities complicating its recognition and treatment, leading to short- and long-term adverse clinical outcomes. There are limited data on the incidence of AKI in Australia using the Kidney Disease Improving Global Outcomes (KDIGO) creatinine-based consensus definition.

Aim: To determine the incidence and estimate the extent of under-reporting of AKI in four hospitals in the South-Eastern Sydney/Illawarra regions of New South Wales, Australia. Read More

Indian J Nephrol 2019 Jan-Feb;29(1):65-69

Department of Nephrology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

A 63-year-old diabetic gentleman with microvascular complications presented with advanced azotemia and anemia. He was stabilized with blood transfusion and hemodialysis. With the probable diagnosis of diabetic nephropathy-related end-stage renal disease, he underwent kidney transplantation. Read More

Mil Med 2019 Feb 27. Epub 2019 Feb 27.

Carl R Darnell Army Medical Center, 36065 Santa Fe Ave, Fort Hood, TX.

Exertional Heat Illness with associated ischemic hepatitis (IH) is a common occurrence among military trainees; however, few specific therapies exist if unresponsive to appropriate supportive measures. A 27-year-old basic combat trainee presented with altered mental status, renal insufficiency, rhabdomyolysis, and a core temp of 107.9 °F after collapsing during a run, leading to the diagnosis of heat stroke. Read More

Tierarztl Prax Ausg K Kleintiere Heimtiere 2019 Feb 26;47(1):37-47. Epub 2019 Feb 26.

Klinik für kleine Haustiere, Freie Universität Berlin.

An impaired elimination of urinary excreted substances and an increase of these substances in the blood (azotemia) can also occur in rabbits and rodents. In addition to renal diseases, prerenal and postrenal conditions can induce azotemia. A systematic evaluation of patients with azotemia is needed to find a diagnosis and to initiate an effective treatment. Read More

J Hosp Med 2019 04 20;14(4):232-238. Epub 2019 Feb 20.

Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Stanford, California.

Acute kidney injury (AKI) is a common complication in hospitalized patients and is associated with mortality, prolonged hospital length of stay, and increased healthcare costs. This paper reviews several areas of controversy in the identification and management of AKI. Serum creatinine and urine output are used to identify and stage AKI by severity. Read More

J Vet Intern Med 2019 Mar 21;33(2):630-639. Epub 2019 Feb 21.

Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, Sweden.

Background: Early detection of decreased glomerular filtration rate (GFR) in dogs is challenging. Current methods are insensitive and new biomarkers are required.

Objective: To compare overall diagnostic performance of serum symmetric dimethylarginine (SDMA) and serum cystatin C to serum creatinine, for detection of decreased GFR in clinically stable dogs, with or without chronic kidney disease (CKD). Read More

Clin Interv Aging 2019 30;14:225-229. Epub 2019 Jan 30.

Department of Nephrology, University Côte d'Azur, University Hospital of Nice, Nice, France.

Purpose: Water balance disorders are associated with a high risk of death in elderly patients. The role of osmotic stress intensity and its direction toward hypo- or hypernatremia is a matter of controversy regarding patients' survival. The aims of this study were, first, to measure the frequency of cellular hydration disorders in patients over 75 years old hospitalized in nephrology department for reversible acute renal failure, and second, to compare the impact of hyperhydration and hypohydration on the risk of death at 6 months. Read More

J Vet Intern Med 2019 Mar 18;33(2):686-693. Epub 2019 Feb 18.

Institute of Veterinary Clinical Science, School of Veterinary Medicine, College of Bio-Resources and Agriculture, National Taiwan University, Taipei, Taiwan.

Background: Indoxyl sulfate (IS) has been reported not only to increase with the severity of impaired renal function, but also possibly to be a factor associated with bone abnormalities linked to fibroblast growth factor-23 (FGF-23) in humans with chronic kidney disease (CKD). It is not yet known whether this correlation between IS and FGF-23 holds true for cats with CKD.

Hypothesis: Accumulation of IS is related to FGF-23 secretion in cats with CKD. Read More

Hemodial Int 2019 Apr 18;23(2):E69-E71. Epub 2019 Feb 18.

Department of Nephrology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Patients with end stage renal disease (ESRD) and severe hyponatremia always pose a challenge to manage. It is necessary to correct biochemical parameters, advanced azotemia, and fluid overload with conventional haemodialysis (HD) but it may correct serum sodium (Na) rapidly resulting in neurological complications like seizures and osmotic demyelination syndrome. Continuous renal replacement therapy (CRRT) is an ideal modality to manage such patients. Read More

J Vet Intern Med 2019 Mar 14;33(2):654-661. Epub 2019 Feb 14.

Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul, Minnesota.

Background: Active kidney injury may play a role in chronic kidney disease (CKD) progression in dogs. Neutrophil gelatinase-associated lipocalin (NGAL), a novel tubular kidney injury biomarker, may help differentiate progressive CKD from stable CKD in dogs.

Objectives: To determine if urinary NGAL : creatinine ratio (UNCR) differentiates stable and progressive CKD in dogs. Read More

J Vet Intern Med 2019 Mar 13;33(2):1009-1014. Epub 2019 Feb 13.

Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota.

A 2-year-old mixed breed goat was presented for a 1-day history of anorexia and 1 week of weight loss. Serum biochemistry disclosed severe azotemia. Abdominal ultrasound examination showed decreased renal corticomedullary distinction, poor visualization of the renal pelves, and dilated ureters. Read More

J Vet Intern Med 2019 Mar 13;33(2):508-515. Epub 2019 Feb 13.

Department of Clinical Science and Services, Small Animal Medicine and Surgery Group, The Royal Veterinary College, Hertfordshire, United Kingdom.

Background: Iatrogenic hypothyroidism might worsen the prognosis of cats with azotemic CKD after thyroidectomy. Varying thyroxine concentrations influence utility of creatinine in assessing renal function. Symmetric dimethylarginine (SDMA) has limited studies in cats with changing thyroid status. Read More

Tierarztl Prax Ausg K Kleintiere Heimtiere 2018 Dec 18;46(6):370-379. Epub 2019 Jan 18.

Objective: To investigate the prevalence and etiology of an increased concentration of ionized magnesium (iMg) in dogs and to evaluate its prognostic relevance.

Materials And Methods: From April 2009 to December 2013, serum electrolytes were measured in 9950 dogs using an ion-selective electrode. Inclusion criterion was an iMg concentration ≥ 0. Read More

Indian J Nephrol 2018 Nov-Dec;28(6):477-481

Laboratory of Pathology Souss, Agadir, Morocco.

Allopurinol-induced drug reactions with eosinophilia and systemic symptoms (DRESS) is a severe illness related to hypersensitivity syndrome characterized by fever, skin rash, lymph node enlargement, hematological abnormalities, especially eosinophilia and atypical lymphocytosis, and single or multiple organ involvement. The syndrome is difficult to diagnose in view of its clinical heterogeneity and long latency period within 8 weeks after start treatment. We report a case of DRESS syndrome in a 64-year-old man, induced by allopurinol treatment for asymptomatic hyperuricemia, started 8 weeks earlier but stopped only 3 days after because of the onset of rash. Read More

Scand J Gastroenterol 2018 Dec 8;53(12):1590-1596. Epub 2019 Jan 8.

a Department of Critical Care Medicine , Beijing Ditan Hospital, Capital Medical University , Beijing , PR China.

Introduction: Acute kidney injury (AKI) is a common and devastating complication in patients with cirrhosis. In 2015, the International Club of Ascites (ICA) proposed the definition of hepatorenal syndrome (HRS) type of AKI (HRS-AKI) in patients with cirrhosis. This study aims to evaluate the criteria of HRS-AKI in patients with cirrhosis admitted to ICU with regard to the prognosis. Read More

Vet J 2019 Jan 30;243:82-90. Epub 2018 Nov 30.

Department of Clinical Bacteriology and Mycology, The Kimron Veterinary Institute, Bet Dagan, Israel. Electronic address:

Disseminated canine mold infections are reviewed. Case inclusion criteria were dogs as hosts, two or more non-adjacent organs affected and identification of the etiological agent at least to the genus level. Of the 157 cases identified, 59. Read More

Semin Nephrol 2019 01;39(1):96-106

Center for Critical Care Nephrology, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA.

Acute kidney injury (AKI) now is recognized as a systemic disease. It occurs frequently in critically ill patients and has profound effects on morbidity and mortality. Recent research efforts have shown a bidirectional interplay between AKI and the immune system. Read More

Semin Nephrol 2019 01;39(1):17-30

University College London Centre for Nephrology, Division of Medicine, University College London Medical School, Royal Free Hospital, London, UK. Electronic address:

Acute kidney injury (AKI) is a common presentation in patients with advanced cirrhosis hospitalized with acute decompensation. A new revised classification now divides AKI in cirrhotic patients into two broad subgroups: hepatorenal syndrome AKI (HRS AKI) and non-hepatorenal syndrome AKI (non-HRS AKI). HRS AKI represents the end-stage complication of decompensated cirrhosis with severe portal hypertension and is characterized by worsening of renal function in the absence of prerenal azotemia, nephrotoxicity, and intrinsic renal disease. Read More

J Med Biochem 2018 Jul 1;37(3):346-354. Epub 2018 Jul 1.

Department of Clinical Biochemistry, Ankara Training and Research Hospital, Ministry of Health,Ankara, Turkey.

Background: The aim of this study is to determine whether the saliva analysis is an alternative to routine biochemical and immunoassay analyses in patients undergoing perito - neal dialysis (PD) or hemodialysis (HD).

Methods: Study group consisted of 40 healthy control, 44 PD and 44 HD patients. Routine biochemical analytes, thyroid stimulating hormone (TSH), free T3, free T4, vitamin B12, ferritin and folic acid were measured. Read More

Nutr Clin Pract 2018 Dec 26. Epub 2018 Dec 26.

School of Health Professions, Department of Clinical and Preventive Nutrition Sciences, Rutgers University, Brunswick, New Jersey, USA.

Acute kidney injury (AKI) is common among critically ill patients. There are a number of nutrition considerations in the management of AKI, including fluid balance, electrolyte and acid-base disturbances, protein provision, and management of comorbid conditions. The optimal amount of protein provision for patients with AKI who are not on renal replacement therapy (RRT) has been a topic of debate for years. Read More

Vet Med (Auckl) 2018 27;9:73-78. Epub 2018 Nov 27.

Interventional Radiology/Endoscopy Department, ACCESS Specialty Animal Hospital, Culver City, CA, USA.

Purpose: We describe a case of ureteral obstruction and fungal pyelonephritis in a cat. The case was managed successfully with a subcutaneous ureteral bypass (SUB) device and systemic antifungal medication.

Case Summary: A 9-year-old, male, neutered, domestic shorthair cat was referred for severe azotemia, ureteral obstruction, and sonographically identified progressive pyelectasia of the left kidney. Read More

Open Vet J 2018 19;8(4):441-444. Epub 2018 Nov 19.

Hokkaido University Veterinary Teaching Hospital, Kita 19, Nishi 10, Kita-ku, Sapporo, Hokkaido 060-0819, Japan.

A 10-year-old castrated male cross-breed dog was referred for the repair of perineal hernia with bladder retroflexion and a mass lesion in the hernial sac. Surgical treatment was performed and the mass was identified as degenerated adipose tissue that was suspected to be derived from the omentum. The hernial contents were reduced without difficulty, and the dog exhibited a normal recovery. Read More

Rev Chilena Infectol 2018 ;35(3):225-232

Escuela Superior de Medicina, Instituto Politécnico Nacional, Instituto Mexicano del Seguro Social, México, D.F, México.

Background: Peritonitis is the most important and frequent complication of peritoneal dialysis (PD). Bacterial infections are responsible in most cases, with characteristic symptoms.

Aim: To determine the most frequent pathogens in peritonitis associated with PD in patients with chronic renal failure (CRF). Read More

Clin Nephrol 2019 Feb;91(2):107-113

BK virus is a known cause of renal failure in kidney transplant recipients, but there is little data regarding its effect on native kidneys in heart transplant patients. Here, we describe the case of a child who underwent heart transplantation and was later diagnosed with BK virus with multiorgan involvement. This patient was diagnosed with dilated cardiomyopathy at 4 months of age and underwent heart transplantation at the age of 5 years. Read More

Stem Cell Res Ther 2018 12 10;9(1):344. Epub 2018 Dec 10.

Graduate Institute of Medical Genomics and Proteomics, National Taiwan University College of Medicine, Taipei, Taiwan.

Background: Renal ischemia-reperfusion (I/R) injury is a major cause of acute kidney injury (AKI), which is associated with high morbidity and mortality. AKI is a serious and costly medical condition. Effective therapy for AKI is an unmet clinical need, and molecular mechanisms underlying the interactions between an injured kidney and distant organs remain unclear. Read More

Mymensingh Med J 2018 Oct;27(4):866-868

Dr Mohammad Omar Faruque Miah, Senior Clinical Pathologist, Department of Pathology, Mymensingh Medical College Hospital, Mymensingh, Bangladesh.

A 52 years old male was admitted at National Institute of Kidney Diseases & Urology, Dhaka, Bangladesh on 16th September 2016 with the history of oliguria, nausea, vomiting & swelling of both legs following consumption of rohu fish gall bladder for the permanent remedy of recurrent abdominal discomfort. He was admitted and received antiemetic, proton pump inhibitor. He had azotemia & underwent urgent haemodialysis (HD). Read More

Clin Epidemiol 2018 26;10:1583-1598. Epub 2018 Oct 26.

Division of Nephrology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan,

Objective: Prompt assessment of perioperative complications is critical for the comprehensive care of surgical patients. Acute kidney injury requiring dialysis (AKI-D) is associated with high mortality, yet little is known about how long-term outcomes of patients have evolved. The association of AKI-D with postsurgical outcomes has not been well studied. Read More

Turk J Gastroenterol 2019 Mar;30(3):299-302

Department of Pathology, Necmettin Erbakan University School of Medicine, Konya, Turkey.

Fixed drug eruption (FDE) is a type of drug reaction characterized by localized erythema, hyperpigmentation, and bullous at the same site(s), generally observed following every intake of a causative drug. Delayed-type cellular hypersensitivity (Type IVC) is considered to play a role in FDE etiology. Several antibiotics, barbiturates, oral contraceptives, nonsteroidal anti-inflammatory drugs, laxative-containing phenolphthalein, metronidazole, and quinine are known to be the primary drugs responsible for FDE. Read More

J Am Vet Med Assoc 2018 Dec;253(11):1452-1459

CASE DESCRIPTION A 9-year-old spayed female Dalmatian was examined because of progressive pelvic limb paraparesis. CLINICAL FINDINGS The dog had a history of chronic urinary incontinence and had been treated with phenylpropanolamine (PPA) for almost 8.5 years. Read More

Open Access Maced J Med Sci 2018 Sep 23;6(9):1678-1681. Epub 2018 Aug 23.

Nephrology Department, University Children Hospital, Skopje, Republic of Macedonia.

Background: Neonatal renal vein thrombosis is the most common vascular condition in the newborn kidney, which could lead to serious complication in infants.

Case Report: We report a case of the unilateral renal vein and inferior vena cava thrombosis, presented with gross hematuria and thrombocytopenia in a neonate. The neonate was a macrosomic male born to a mother with hyperglycemia in pregnancy. Read More

J Vet Intern Med 2018 Nov 13;32(6):1874-1885. Epub 2018 Oct 13.

Department of Small Animal Internal Medicine, Koret School of Veterinary Medicine - Veterinary Teaching Hospital and Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, Rehovot, Israel.

Background: Pancreatitis in cats (FP) has been increasingly diagnosed in recent years, but clinical studies of large numbers of affected cats are scarce.

Objectives: To describe a large cohort of cats with FP requiring hospitalization.

Animals: One hundred and fifty-seven client-owned cats. Read More

J Am Vet Med Assoc 2018 Nov;253(9):1169-1176

CASE DESCRIPTION A 7-year-old female domestic shorthair cat was referred for evaluation of azotemia and unilateral hydronephrosis. CLINICAL FINDINGS Abdominal ultrasonography revealed right-sided hydronephrosis and dilation of the proximal aspect of the ureter; the left kidney was small with irregular margins. A highly vascular, irregular retroperitoneal mass, not clearly associated with the ureteral obstruction, was also visualized. Read More

Biosens Bioelectron 2019 Jan 20;123:36-50. Epub 2018 Sep 20.

Department of Biochemistry, M.D. University, Rohtak 124001, Haryana, India.

Urea is the major end product of nitrogen metabolism in humans, which is eliminated from the body mainly by the kidneys through urine but is also secreted in body fluids such as blood and saliva. Its level in urine ranges from 7 to 20 mg/dL, which drastically rises under patho-physiological conditions thus providing key information of renal function and diagnosis of various kidney and liver disorders. Increase in urea levels in blood, also referred to as azotemia or uremia. Read More

Vet Ophthalmol 2018 Oct 5. Epub 2018 Oct 5.

Small Animal Clinic, College of Veterinary Medicine, University of Leipzig, Leipzig, Germany.

Objective: The aim of the study was to determine the lacrimal fluid (LF) contents of glucose, urea nitrogen, and creatinine in cats.

Animal Studied: A total of 96 cats were included in the study.

Procedure: Venous blood and LF samples were collected. Read More

Ticks Tick Borne Dis 2019 01 11;10(1):124-126. Epub 2018 Sep 11.

Diagnostic Medicine/Pathobiology, College of Veterinary Medircine, Kansas State University, 1800 Denison Ave., Manhattan, KS 66506, USA. Electronic address:

A possible novel Babesia species infection of a maned wolf (Chrysocyon brachyurus) was first reported in 2012. The current case details a confirmed report of a maned wolf with infection by an undetermined species of Babesia. As the mortality and morbidity of babesiosis is high, this may become a significant concern to captive maned wolves, which are considered a near-threatened species by the World Association of Zoos and Aquariums. Read More

ACG Case Rep J 2018 29;5:e62. Epub 2018 Aug 29.

Division of Gastroenterology Hepatology and Nutrition, NYU-Winthrop Hospital, Mineola, NY.

Cholesterol crystal embolism can be spontaneous or iatrogenic, and it can involve any organ of the gastrointestinal tract, presenting with common gastrointestinal symptoms such as bleeding, perforation, obstruction, and inflammation. It is therefore considered the "great masquerader," requiring a high level of suspicion because the condition is associated with increased morbidity and mortality. We present a 69-year-old man who presented with gastrointestinal bleeding and azotemia. Read More

Clin Case Rep 2018 Sep 25;6(9):1801-1806. Epub 2018 Jul 25.

University of Pennsylvania Philadelphia PA USA.

Implant associated granulomatous inflammation causing hypercalcemia can occur following use of commercial xenogeneic pericardial tissue patches in dogs. Removal of the implant can result in resolution of the hypercalcemia, suggesting a causal relationship between the tissue reaction to a xenogeneic implant and development of hypercalcemia. Read More

J Zoo Wildl Med 2018 Sep;49(3):722-731

The aims of this study were to determine if a propofol constant rate infusion (CRI) in Speke's gazelle, Gazella spekei, would serve as an effective alternative maintenance anesthetic, result in shorter recovery times, and improve anesthetic recovery quality when compared with isoflurane. Eight adult gazelle were enrolled in this complete crossover study with a minimum 3-wk washout period. All gazelle were induced with 10 mg/kg intravenous propofol and maintained with either propofol CRI (0. Read More