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    1 OF 1332

    Vitamin D status, hypertension and body mass index in an urban black community in Mangaung, South Africa.
    Afr J Prim Health Care Fam Med 2016 Oct 31;8(1):e1-e5. Epub 2016 Oct 31.
    Department of Nutrition and Dietetics, University of the Free State.
    Background: A strong relationship exists between hypertension and body weight. Research has linked both higher blood pressure and body weight with lower vitamin D status.

    Objective: This study assessed the vitamin D status of a low-income, urban, black community in South Africa, to examine whether serum levels of 25-hydroxy vitamin D [25(OH)D] are associated with hypertension and body mass index (BMI). Read More

    Effects of an L-arginine-based multi ingredient product on endothelial function in subjects with mild to moderate hypertension and hyperhomocysteinemia - a randomized, double-blind, placebo-controlled, cross-over trial.
    BMC Complement Altern Med 2017 Feb 2;17(1):92. Epub 2017 Feb 2.
    Nutritional CRO, BioTeSys GmbH, Schelztorstraße 54-56, 73728, Esslingen, Germany.
    Background: Nutrition plays an important role in prevention and management of cardiovascular diseases (CVD) in early stages. Recent research demonstrated beneficial effects of various nutritional ingredients on vascular health. The aim of the current study was to evaluate the effects of an L-arginine-based multi ingredient product (AbMIP) on vascular function. Read More

    Vitamin B12 deficiency neuropathy; a rare diagnosis in young adults: a case report.
    BMC Res Notes 2017 Jan 28;10(1):72. Epub 2017 Jan 28.
    Department of Medicine, Faculty of Health Sciences, University of Buea and Global Health Dialogue Foundation, Buea, Cameroon.
    Background: Vitamin B12 deficiency is a metabolic disorder with many causes. It often presents with megaloblastic anaemia and neurological disorders which entail prompt treatment. The diagnosis of Vitamin B12 deficiency is challenging in resource limited-settings due to limited access to diagnostic tools and unfamiliarity with the disease, owing to its rarity especially in young people. Read More

    Cystatin C is Better than Serum Creatinine for Estimating Glomerular Filtration Rate to Detect Osteopenia in Chronic Kidney Disease Patients.
    Yonsei Med J 2017 Mar;58(2):380-387
    Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
    Purpose: Recent studies have reported that loss of bone mass is associated with renal function decline and increased fracture risks in chronic kidney disease (CKD) patients. The aim of this study was to investigate the best estimated glomerular filtration rate (eGFR) equation to detect osteopenia in CKD patients.

    Materials And Methods: This was a cross-sectional study, and 780 patients aged 50 years or above were classified into normal bone mass or osteopenia groups according to the -1. Read More

    Rapid healing of a patient with dramatic subacute combined degeneration of spinal cord: a case report.
    BMC Res Notes 2017 Jan 3;10(1):18. Epub 2017 Jan 3.
    Department of Neurology, Justus-Liebig-University Giessen, Klinikstraße 33, 35385, Gießen, Germany.
    Background: Prevalence of cobalamin deficiency is high especially in older patients and an immediate therapy start is necessary to prevent irreversible neurological damages. Unfortunately, the diagnosis of cobalamin deficiency is difficult and at present, there is no consensus for diagnosis of this deficiency. Therefore, we aim to elucidate a meaningful diagnostic pathway by a case report with an initially misleading medical history. Read More

    Hypovitaminosis D and "small burden" uterine fibroids: Opportunity for a vitamin D supplementation.
    Medicine (Baltimore) 2016 Dec;95(52):e5698
    aWoman's Health Sciences Department, Gynecologic Section, Polytechnic University of Marche bDepartment of Clinical Sciences, Section of Biochemistry, Biology and Physics, Polytechnic University of Marche, Ancona, Italy.
    The aim of this study was to evaluate the effect of vitamin D supplementation in women with hypovitaminosis D and "small burden" uterine fibroids.This study focused on 208 women diagnosed with uterine fibroids and concomitant hypovitaminosis D, from January to December 2014. One hundred eight women of the initial study population were diagnosed with "small burden" uterine fibroids. Read More

    Effect of vitamin D3 on self-perceived fatigue: A double-blind randomized placebo-controlled trial.
    Medicine (Baltimore) 2016 Dec;95(52):e5353
    aDepartment of Internal Medicine bInstitute for Clinical Chemistry, University Hospital Zurich and University of Zurich cDivision of Endocrinology, Diabetology and Clinical Nutrition dDepartment of Geriatrics, University Hospital Zurich, Zurich eDepartment of Internal Medicine, Spital Linth, Uznach, Switzerland.
    Background: Vitamin D deficiency is frequent and has been associated with fatigue in uncontrolled trials.

    Methods: This is the first double-blind placebo-controlled clinical trial to investigate the efficacy of per os vitamin D3 (cholecalciferol) in treating fatigue among otherwise healthy persons with low serum 25-hydroxyvitamin D (25(OH)D) levels. We enrolled 120 individuals (mean age 29 ± 6 years, 53% women) presenting with fatigue and vitamin D deficiency (serum 25(OH)D < 20 μg/L). Read More

    Prevalence of Low Vitamin D Levels in Patients With Orthopedic Trauma.
    Am J Orthop (Belle Mead NJ) 2016 Nov/Dec;45(7):E522-E526
    Department of Orthopaedic Surgery, University of Missouri, Columbia, MO.
    Low levels of serum vitamin D have been linked to numerous musculoskeletal and nonmusculoskeletal conditions. Vitamin D deficiency appears relatively high among various patient subpopulations, including patients with fracture nonunion. We conducted a retrospective study to determine the prevalence of vitamin D deficiency and insufficiency in a large population of patients with orthopedic trauma. Read More

    Association between the Achievement of Target Range CKD-MBD Markers and Mortality in Prevalent Hemodialysis Patients in Taiwan by Using the Kidney Disease: Improving Global Outcomes Clinical Guidelines.
    Biomed Res Int 2016 27;2016:1523124. Epub 2016 Nov 27.
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan.
    Background. This study evaluated the association between achieving target chronic kidney disease-mineral and bone disorder (CKD-MBD) marker levels and mortality in Taiwanese hemodialysis (HD) patients. Target levels were based on the Kidney Disease: Improving Global Outcomes (KDIGO) guidelines. Read More

    Vitamin D Deficiency - Is There Really a Pandemic?
    N Engl J Med 2016 Nov;375(19):1817-1820
    From the Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston (J.E.M.); the Division of Nutritional Sciences, Cornell University, Ithaca, NY (P.M.B.); the Center for Clinical and Translational Medicine, Maine Medical Center Research Institute, Scarborough (C.J.R.); and the Office of Dietary Supplements, National Institutes of Health, Bethesda, MD (C.L.T.).

    Vitamin D and retinal microvascular damage: The Rotterdam Study.
    Medicine (Baltimore) 2016 Dec;95(49):e5477
    aDepartment of Epidemiology bDepartment of Ophthalmology cDepartment of Radiology dDepartment of Neurology, Erasmus University Medical Center, Rotterdam, The Netherlands eDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts fDepartment of Retinal Signal Processing, Netherlands Institute for Neuroscience gDepartment of Ophthalmology, Academic Medical Center, Amsterdam hDepartment of Ophthalmology, Leiden University Medical Center, Leiden iDepartment of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
    Vitamin D has been linked to various cardiovascular risk factors including indices of large-vessel disease. However, it remains unclear whether vitamin D is also associated with microvascular damage. In a community-dwelling population, we studied associations between vitamin D serum levels and retinal microvascular damage defined as retinopathy signs, narrower arterioles, and wider venules. Read More

    Assessment of 3-epi-25-hydroxyvitamin D levels during cholecalciferol supplementation in adults with chronic liver diseases.
    Appl Physiol Nutr Metab 2016 Dec;41(12):1311-1317
    b Institute of Bioanalytical Chemistry, Saarland University, Saarbrücken, Germany.
    Recently, hepatic immaturity was cited as a possible reason for high levels of the C-3 epimer of 25-hydroxyvitamin (25(OH)D) in premature infants: however what role, if any, the liver plays in controlling epimer concentrations is unknown. This study assesses 3-epi-25-hydroxyvitamin D (3-epi-25(OH)D) levels during the course of cholecalciferol supplementation in adults with chronic liver diseases (CLD). Vitamin D metabolites were analyzed in 65 CLD patients with 25(OH)D <30 ng/mL who received 20 000 IU cholecalciferol/week for 6 months. Read More

    Isolated Common Hepatic Artery Branch Thrombosis: Results and Risk Factors.
    Acta Med Iran 2016 Sep;54(9):610-613
    Department of Surgery, School of Medicine, Kashan University of Medical Sciences, Kashan, Iran.
    Isolated common hepatic artery branch thrombosis with severe gastric ischemia and duodenojejunal infarction is a rare condition; it usually presents with acute abdomen and may be associated with underlying thrombotic risk factors. We present a 35-year-old man admitted to our hospital with five days history of sudden abdominal pain and deteriorating epigastric pain. He was a driver and had no any past medical history. Read More

    Vitamin D supplementation for preventing infections in children under five years of age.
    Cochrane Database Syst Rev 2016 11 9;11:CD008824. Epub 2016 Nov 9.
    Departments of Epidemiology and Nutrition, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA, USA, 02115.
    Background: Vitamin D is a micronutrient important for bone growth and immune function. Deficiency can lead to rickets and has been linked to various infections, including respiratory infections. The evidence on the effects of supplementation on infections in children has not been assessed systematically. Read More

    Berberine activates peroxisome proliferator-activated receptor gamma to increase atherosclerotic plaque stability in Apoe(-/-) mice with hyperhomocysteinemia.
    J Diabetes Investig 2016 Nov 15;7(6):824-832. Epub 2016 Apr 15.
    Central Laboratory, The Second Hospital of Jilin University, Changchun, China.
    Aims/introduction: An elevated level of plasma homocysteine has long been suspected as a metabolic risk factor for the development of atherosclerotic vascular diseases in diabetes. Berberine (BBR) has several preventive effects on cardiovascular diseases. The effects of BBR on atherosclerotic plaque stability increased by homocysteine thiolactone (HTL) remain unknown. Read More

    Vitamin D profile of patients with spinal cord injury and post-stroke hemiplegia: All in the same boat.
    J Back Musculoskelet Rehabil 2016 Apr;29(2):205-210
    Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Cukurova University, Adana, Turkey.
    Background: Patients with spinal cord injury (SCI) and hemiplegia are at risk of fractures partly due to decreased bone mineral density with relation to the low levels of vitamin D.

    Objective: The objective of this study is to evaluate the vitamin D profile of patients with SCI and post-stroke hemiplegia.

    Methods: 25(OH)D levels of patients with SCI and hemiplegia were obtained from the electronic medical record database and compared with age- and sex-matched non-disabled controls. Read More

    ABC Transporter Subfamily D: Distinct Differences in Behavior between ABCD1-3 and ABCD4 in Subcellular Localization, Function, and Human Disease.
    Biomed Res Int 2016 28;2016:6786245. Epub 2016 Sep 28.
    Department of Biological Chemistry, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan.
    ATP-binding cassette (ABC) transporters are one of the largest families of membrane-bound proteins and transport a wide variety of substrates across both extra- and intracellular membranes. They play a critical role in maintaining cellular homeostasis. To date, four ABC transporters belonging to subfamily D have been identified. Read More

    Vitamin D Repletion in Kidney Stone Formers: A Randomized Controlled Trial.
    J Urol 2016 Oct 17. Epub 2016 Oct 17.
    Department of Urology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania. Electronic address:
    Purpose: Vitamin D deficiency is often detected during metabolic evaluation in the nephrolithiasis population. Multiple vitamin D repletion protocols exist, although their differing impact on urinary stone formation risk factors is unclear.

    Materials And Methods: Patients with a history of calcium stones and vitamin D deficiency (less than 30 ng/ml) were randomized to receive either 1,000 IU daily or 50,000 IU weekly of vitamin D supplementation for 6 weeks. Read More

    Association of plasma 25-hydroxyvitamin D with physical performance in physically active children.
    Appl Physiol Nutr Metab 2016 Nov 13;41(11):1124-1128. Epub 2016 Jul 13.
    a Rabta Hospital, Laboratory of Biochemistry, LR99ES11, 1007 Tunis, Tunisia.
    Vitamin D is thought to regulate skeletal muscle function and boost physical performance. The aim of this study was to assess the relationship between vitamin D and physical performance in physically active children. This cross-sectional study included 125 children who practice football as a leisure activity. Read More

    Wernicke's encephalopathy due to hyperemesis gravidarum: Clinical and magnetic resonance imaging characteristics.
    J Postgrad Med 2016 Oct-Dec;62(4):260-263
    Department of Neurology, Malabar Institute of Medical Sciences, Calicut, Kerala, India.
    Hyperemesis gravidarum-induced Wernicke's encephalopathy (WE) is an underestimated condition. The purpose of this study is to improve its awareness and early diagnosis. We report five cases of WE secondary to hyperemesis gravidarum. Read More

    Vitamin D deficiency in critically ill children with sepsis.
    Paediatr Int Child Health 2016 Feb 27;36(1):15-21. Epub 2015 Jun 27.
    Department of Paediatrics, Advanced Paediatric Center, Postgraduate Institute of Medical Education and Research (PGIMER) , Chandigarh, India.
    Background: Data on the prevalence of vitamin D deficiency (VDD) in critically ill children with sepsis and its association with illness severity and outcome are limited.

    Aim: To investigate the prevalence of VDD in critically ill children with sepsis.

    Methods: One hundred and twenty-four critically ill children with sepsis aged 1-12 years were prospectively enrolled in a paediatric intensive care unit (PICU) in North India over a 1-year period. Read More

    Bone Histology of Two Cases with Osteomalacia Related to Low-dose Adefovir.
    Intern Med 2016;55(20):3013-3019. Epub 2016 Oct 15.
    Nephrology Center, Toranomon Hospital, Japan.
    We performed a bone histomorphometric analysis in two patients demonstrating Fanconi syndrome with hypophosphatemia, adefovir-related bone disease and chronic hepatitis B infection. Both patients had osteomalacia, but showed two different histological patterns. The osteoid volume of the patient without risedronate increased with [(osteoid volume/ bone volume)×100=18. Read More

    Vitamin D status and glucose metabolism in youth.
    Crit Rev Food Sci Nutr 2017 Jan;57(1):147-151
    a Department of Nutrition , School of Public Health, University of São Paulo , São Paulo , Brazil.
    This study aimed to review and synthesize the available scientific evidence on the relationship between serum 25(OH)D concentrations and glucose metabolism among adolescents. A total of 19 studies were included. Many studies did not find a relation between 25(OH)D concentrations and insulin sensitivity, but most studies have shown that vitamin D status influences glucose dysregulation in youth due to particularities of this life stage. Read More

    The other side of vitamin D therapy: 
a case series of acute kidney injury due to malpractice-related vitamin D intoxication
    Clin Nephrol 2016 Nov;86 (2016)(11):236-241
    Background: Vitamin D deficiency is highly prevalent in Indian Kashmir. Many people get injectable vitamin D (600,000 IU/injection). At times, the dose prescribed is far above the permissible limit. Read More

    Vitamin D status of Māori and non-Māori octogenarians in New Zealand: a Cohort Study (LiLACS NZ).
    Asia Pac J Clin Nutr 2016 Dec;25(4):885-897
    Department of General Practice and Primary Health Care, Faculty of Medical and Health Sciences, University of Auckland, New Zealand.
    Background And Objectives: This study assessed vitamin D status and its determinants in a cohort of octogenarians living within New Zealand's Bay of Plenty and Lakes Districts.

    Methods And Study Design: Serum 25- hydroxyvitamin D [25(OH)D] concentration was measured in 209 Māori (aged 80-90 years) and 357 non-Māori (85 years), along with demographic, lifestyle, supplement use and other health data.

    Results: Mean [95% CI] 25(OH)D concentration was 69 [67 to 72] nmol/L, with 15% >100 nmol/L and 6 individuals >150 nmol/L. Read More

    25 hydroxy vitamin D is higher when a renal multivitamin is given with cholecalciferol at hemodialysis.
    Asia Pac J Clin Nutr 2016 Dec;25(4):754-759
    Department of Nutritional Sciences, Texas Tech University, Lubbock, Texas, USA.
    Background And Objectives: Seventy six hemodialysis (HD) patients were used in a prospective randomized and clinical trial to determine if a multivitamin with vitamin D (cholecalciferol 12,000 IU/week) given during dialysis would improve the vitamin D status of hemodialysis subjects.

    Methods And Study Design: Subjects were randomly assigned to two groups: 37 subjects were in the renal multivitamin without vitamin D (MV) group and 39 subjects were in a multivitamin route with vitamin D (MVD) group (12,000 IU of cholecalciferol per week). All subjects were given 2 multivitamin tablets at their 3 HD sessions each week for 20 weeks. Read More

    Choline and betaine ameliorate liver lipid accumulation induced by vitamin B6 deficiency in rats.
    Biosci Biotechnol Biochem 2017 Feb 4;81(2):316-322. Epub 2016 Oct 4.
    a The United Graduate School of Agricultural Science , Gifu University , Gifu , Japan.
    We investigated the efficacy of supplementing the diet with choline or betaine in ameliorating lipid accumulation induced by vitamin B6 (B6) deficiency in rat liver. Male Wistar rats were fed a control, B6-deficient, choline-supplemented (2, 4, or 6 g choline bitartrate/kg diet) B6-deficient diet or betaine-supplemented (1, 2, or 4 g betaine anhydrous/kg diet) B6-deficient diet for 35 d; all diets contained 9 g L-methionine (Met)/kg diet. Choline or betaine supplementation attenuated liver lipid deposition and restored plasma lipid profiles to control levels. Read More

    Relationships between low serum vitamin D levels and HBV "a" determinant mutations in chronic hepatitis B patients.
    J Infect Dev Ctries 2016 Sep 30;10(9):1025-1030. Epub 2016 Sep 30.
    Medical College of Soochow University, Suzhou, China.
    Introduction: Vitamin D is significantly associated with virus replication in chronic hepatitis B virus (HBV) infection. However, the relationship between low serum vitamin D levels and HBV "a" determinant mutations remains unknown.

    Methodology: A total of 133 chronically HBV-infected, treatment-naive patients were randomly selected in the present study. Read More

    Skeletal deformities associated with nutritional congenital rickets in newborn lambs.
    N Z Vet J 2017 Jan 16;65(1):51-55. Epub 2016 Oct 16.
    b Northern Southland Veterinary Services , 105 Berwick Street, Riversdale , Southland , New Zealand.
    Case History: A group of 545 pregnant rising 2-year-old Coopdale ewes on a Southland sheep farm were grazed over winter on a fodder beet (Beta vulgaris) crop. Subsequently, 45 out of approximately 750 lambs were born with a variety of skeletal deformities, including shortened limbs, varus and valgus angular limb deformities, palmar grade stance and cranial bowing of the carpus. Analysis of the crop showed the fodder beet contained a low percentage of phosphorus. Read More

    Clinical significance of hyperhomocysteinemia in infective endocarditis: A case-control study.
    Medicine (Baltimore) 2016 Sep;95(39):e4972
    aInternal Medicine Section, Department of Cardiothoracic Sciences, University of Naples S.U.N. bUnit of Infectious & Transplant Medicine cUnit of Clinical Biochemistry dUnit of Cardiac Surgery A.O.R.N. dei Colli - Ospedale Monaldi, Napoli, Italy.
    Blood coagulation plays a key role in the pathogenesis of infective endocarditis (IE). Conditions associated with thrombophilia could enhance IE vegetation formation and promote embolic complications.In this study, we assessed prevalence, correlates, and clinical consequences of hyper-homocysteinemia (h-Hcy) in IE. Read More

    Tc-99m-ECD SPECT as the measure for therapeutic response in patients with cobalamin deficiency: Two case reports.
    Medicine (Baltimore) 2016 Sep;95(39):e4851
    aDepartment of Neurology bDepartment of Radiology cDepartment of Nuclear Medicine, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung dSchool of Medicine, Tzu Chi University, Hualien eGraduate Institute of Medical Imaging and Radiological Sciences, Central Taiwan University of Science and Technology, Taichung, Taiwan.
    Background: Cobalamin (Cbl) is an essential vitamin for human health. While an increasing body of evidence supports the negative impact of Cbl deficiency on cognition, the causality has yet to be determined, and the reported therapeutic responses after Cbl supplement therapy have been inconsistent. Besides, few reports have described neuroimaging characteristics associated with the therapeutic response. Read More

    Risk assessment of obstructive sleep apnea syndrome in pediatric patients with vitamin D deficiency: A questionnaire-based study.
    Medicine (Baltimore) 2016 Sep;95(39):e4632
    aDepartment of Pediatrics, Suleymaniye Maternity and Children's Training and Research Hospital bDepartment of Pediatrics, Bezmialem Vakıf University, Faculty of Medicine, İstanbul, Turkey.
    The aim of the following study is to evaluate the risk of obstructive sleep apnea syndrome (OSAS) in subjects with vitamin D deficiency.Prospective and comparative study.We enrolled 240 subjects into the study. Read More

    Estimated serum vitamin D status, vitamin D intake, and risk of incident alopecia areata among US women.
    Arch Dermatol Res 2016 Nov 23;308(9):671-676. Epub 2016 Sep 23.
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02115, USA.
    Studies have identified increased prevalence of vitamin D deficiency in patients with alopecia areata (AA), an autoimmune disease characterized by hair loss, but none have prospectively examined vitamin D status and incident AA. In 55,929 women in the Nurses' Health Study (NHS), we prospectively evaluated the association between estimated vitamin D status, derived from a prediction model incorporating lifestyle determinants of serum vitamin D, and self-reported incident AA. We evaluated dietary, supplemental, and total vitamin D intake as additional exposures. Read More

    Hypovitaminosis D and adipose tissue - cause and effect relationships in obesity.
    Ann Agric Environ Med 2016 Sep;23(3):403-9
    Division of Biology of Civilization-Linked Diseases, Department of Chemistry and Clinical Biochemistry, Poznan University of Medical Sciences, Poland.
    In recent years, attention has been focused on pleiotropic directions of effects exerted by vitamin D. Epidemiological data indicate that deficiency of vitamin D in various population groups represents an increasingly widespread phenomenon, while a decreased serum concentration of calcitriol correlates with manifestation of civilization-linked diseases, including visceral obesity. This study aims at a review and synthesis of data linked to relationships between lowered vitamin D concentrations in blood and manifestation of obesity, and potential mechanisms which affect the concentration of the vitamin in conditions of an excessive accumulation of adipose tissue. Read More

    [Relationship between vitamin D deficiency and early-onset neonatal sepsis].
    Zhongguo Dang Dai Er Ke Za Zhi 2016 Sep;18(9):791-795
    Department of Pediatrics, Third People's Hospital of Chengdu/Second Affiliated Hospital of Chengdu, Chongqing Medical University, Chengdu 610031, China.
    Objective: To evaluate the effect of vitamin D level on early-onset sepsis (EOS) in neonates.

    Methods: Seventy-eight full-term neonates with EOS were used as the research group (EOS group). sixty healthy full-term neonates without clinical and/or laboratory features related to infections were used as the control group. Read More

    Nutraceutical approaches to homocysteine lowering in hypertensive subjects at low cardiovascular risk: a multicenter, randomized clinical trial.
    J Biol Regul Homeost Agents 2016 Jul-Sep;30(3):921-927
    Department of Clinical Research, FADOI Foundation, Milan, Italy.
    Although the role of homocysteine (HCys) in secondary cardiovascular prevention has been scaled down, hyper-homocysteinemia remains a risk factor for cerebrovascular events. The aim of this study was to investigate the efficacy of nutraceuticals in lowering HCys serum levels versus a conventional vitamin supplementation in hypertensive subjects at low cardiovascular risk. One-hundred and four patients (mean age 62. Read More

    Relationship between cardio-ankle vascular index and homocysteine in hypertension subjects with hyperhomocysteinemia.
    Clin Exp Hypertens 2016;38(7):652-657. Epub 2016 Sep 21.
    a Department of Vascular Medicine , Peking University Shougang Hospital , Beijing , P. R. of China.
    Background: Arteriosclerosis evaluated by arterial stiffness is the basic pathophysiological change during the development of hypertension. Cardio-ankle vascular index (CAVI) is an index of arterial stiffness. Hyperhomocysteinemia (HHcy) is an independent risk factor for vascular diseases. Read More

    Lower Plasma Levels of Antioxidant Vitamins in Patients with Metabolic Syndrome: A Case Control Study.
    Adv Clin Exp Med 2016 Jul-Aug;25(4):689-700
    Department of Internal and Infectious Diseases, Medical University of Lodz, Poland.
    Background: Metabolic syndrome (MS) is a coexistence of metabolic risk factors affecting the development of cardiovascular diseases. Reactive oxygen species, which are excessively produced in MS, participate in its pathogenesis. Vitamins A, C and E are an important part of the non-enzymatic antioxidative barrier in humans. Read More

    B-Group Vitamins: Chemoprevention?
    Adv Clin Exp Med 2016 May-Jun;25(3):561-8
    Department of Biochemistry and Biopharmaceuticals, The National Medicines Institute, Warszawa, Poland.
    The importance of vitamins in the prevention of cancer has attracted the attention of consumers, nutritionists and scientists for decades. The mechanisms of carcinogenesis, extended in the context of the function of vitamins, i.e. Read More

    Vitamin D levels, vitamin D supplementation, and prognosis in patients with chronic kidney disease
    Clin Nephrol 2016 Oct;86(10):165-74
    Background: Vitamin D (Vit D) deficiency plays a central role in the pathogenesis of chronic kidney disease (CKD) complications, both skeletal and nonskeletal. The purpose of this study was to examine whether 25(OH)D levels and supplementation with oral cholecalciferol (Vitamin D3 (Vit D3)) are associated with morbidity and mortality among patients with significant CKD.

    Methods: CKD patients attending the nephrology clinic at Shaare Zedek Medical Center between July 1, 2008 and January 31, 2012, tested at least twice for 25(OH)D levels, were enrolled. Read More

    Modification of the association between smoking status and severity of coronary stenosis by vitamin D in patients suspected of coronary heart disease.
    Medicine (Baltimore) 2016 Sep;95(36):e4817
    Heart Center of Beijing Chaoyang Hospital Affiliated to Capital Medical University, Chaoyang District, Beijing, China.
    Given both smoking and vitamin D are associated with coronary heart disease (CHD) via inflammation and smoking may interfere with the local antiinflammatory effects of vitamin D. We hypothesized that the relationship between smoking and severity of CHD may be modified by vitamin D.A cross-sectional study was conducted. Read More

    Cerebral salt-wasting syndrome in a child with Wernicke encephalopathy treated with fludrocortisone therapy: A case report.
    Medicine (Baltimore) 2016 Sep;95(36):e4393
    aDepartment of Pediatrics bResearch Institute of Clinical Medicine, Chonbuk National University Medical School, Jeonju, Korea.
    Rationale For This Case Report: Cerebral Salt-Wasting Syndrome (CSWS) is characterized by hyponatremia and sodium wasting in the urine. These conditions are triggered by various neurosurgical disorders such as subarachnoid hemorrhage, brain tumor, head injury, and brain surgery. To our knowledge, CSWS caused by Wernicke encephalopathy (WE) has been rarely reported. Read More

    Adequate vitamin D status is associated with the reduced odds of prevalent diabetic retinopathy in African Americans and Caucasians.
    Cardiovasc Diabetol 2016 09 1;15(1):128. Epub 2016 Sep 1.
    Department of Ophthalmology and Visual Sciences, School of Medicine and Public Health, The University of Wisconsin-Madison, Madison, WI, USA.
    Background: Vitamin D status has been hypothesized to protect against development of diabetic retinopathy via its anti-inflammatory and anti-angiogenic properties. Additionally, in vitro and in vivo studies suggest vitamin D favorably influences blood pressure and blood glucose control, strong risk factors for diabetic retinopathy. We examined the association between vitamin D status and prevalent diabetic retinopathy in participants with diabetes from a population-based cohort. Read More

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