3,260 results match your criteria Avian Pathology[Journal]

Comparative Pathogenesis of Turkey Reoviruses.

Avian Pathol 2022 May 18:1-26. Epub 2022 May 18.

Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 55108, USA.

Turkey reoviruses have been implicated in multiple disease syndromes resulting in significant economic losses to the turkey industry. Turkey enteric reovirus (TERV) has been known to be involved in poult enteritis complex for decades, but turkey arthritis reovirus (TARV), the causative agent of tenosynovitis in turkeys, emerged in 2011. Recently in 2019, we isolated reovirus from several cases of hepatitis in turkeys and tentatively named it as turkey hepatitis reovirus (THRV). Read More

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Differential expression of microRNAs in the caecal content and faeces of broiler chickens experimentally infected with .

Avian Pathol 2022 May 18:1-27. Epub 2022 May 18.

Pathobiology and Population Sciences, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Herts, AL9 7TA.

Coccidiosis caused by spp. incurs significant morbidity and mortality in chickens, and is thus of great economic importance. Post-mortem intestinal lesion scoring remains one of the most common means of diagnosis, and therefore alternative, non-invasive methods of diagnosis and monitoring would be highly desirable. Read More

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Phenotypic antimicrobial resistance (AMR) of avian pathogenic (APEC) from broiler breeder flocks between 2009 and 2018.

Avian Pathol 2022 May 9:1-23. Epub 2022 May 9.

ICBAS - Instituto de Ciências Biomédicas de Abel Salazar, Universidade do Porto, Rua Jorge de Viterbo Ferreira, 228, 4050-313 Porto, Portugal.

Colibacillosis is one of the most important diseases in poultry production. The use of antimicrobials remains a therapeutic cornerstone for avian pathogenic (APEC), thereby contributing to the development of antimicrobial resistance (AMR). The aim of this study was to characterize AMR in broiler breeder flocks reared under commercial conditions. Read More

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Study on the mechanism of infection on chicken tracheal mucosa injury.

Avian Pathol 2022 May 3:1-0. Epub 2022 May 3.

College of Animal Science, Fujian Agriculture and Forestry University, Fuzhou 8 350002, People's Republic of China.

(MG) is a pathogenic microorganism that causes serious harm to the poultry industry. It is mainly adsorbed on the cilia and mucosa of respiratory epithelial cells, causing tracheal mucosal damage or cilia loss, causing chronic respiratory disease (CRD). In order to study the effect of MG infection on chicken tracheal mucosa injury and explore its possible mechanism, specific-pathogen-free (SPF) chickens were challenged with wild-type strain MG-HY. Read More

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Neuronal satellitosis is a common finding in the avian brain.

Avian Pathol 2022 May 3:1-41. Epub 2022 May 3.

Department of Veterinary Medicine, University of Perugia, Via San Costanzo, 4, 06126 Perugia, Italy.

Perineuronal or neuronal satellitosis is the term describing the presence of glial cells in the satellite space surrounding the neuronal perikaryon. Confusingly, this finding has been described both as a physiologic and pathologic condition in humans and animals. In animals, neuronal satellitosis has been described in mammals, as well as in avian species. Read More

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Antimicrobial susceptibility, plasmid replicon typing, phylogenetic grouping, and virulence potential of avian pathogenic and faecal isolated from meat chickens in Australia.

Avian Pathol 2022 Apr 13:1-32. Epub 2022 Apr 13.

School of Veterinary Science, The University of Queensland, Gatton, Queensland 4343, Australia.

Globally, avian colibacillosis is a leading cause of morbidity and mortality in poultry, associated with economic losses and welfare problems. Here, clinical avian pathogenic isolates (CEC; n=50) and faecal isolates from healthy (FEC; n=187) Australian meat chickens collected between 2006 and 2014 were subjected to antimicrobial susceptibility testing, phylogenetic grouping, plasmid replicon (PR) typing, multilocus sequence typing, and virulence gene (VG) profiling. Extended-spectrum cephalosporin (ESC)- and fluoroquinolone (FQ)-resistant isolates underwent further genetic characterisation. Read More

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Pathological effect of different avian infectious bronchitis virus strains on the bursa of Fabricius of chickens.

Avian Pathol 2022 May 9:1-10. Epub 2022 May 9.

Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing, People's Republic of China.

Infectious bronchitis is an acute and highly contagious disease caused by avian infectious bronchitis virus (IBV). As well as the typical clinical respiratory signs, such as dyspnoea and tracheal rales, QX genotype strains can also cause damage to the urinary system and reproductive system. Our previous studies found that chickens infected with QX-type IBV also displayed damage to the bursa of Fabricius. Read More

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Strategies for enhancing immunity against avian influenza virus in chickens: a review.

Avian Pathol 2022 May 5:1-25. Epub 2022 May 5.

Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Canada.

Poultry infection with avian influenza viruses (AIV) is a continuous source of concern for poultry production and human health. Uncontrolled infection and transmission of AIV in poultry increase the potential for viral mutation and reassortment, possibly resulting in the emergence of zoonotic viruses. To this end, implementing strategies to disrupt the transmission of AIV in poultry, including a wide array of traditional and novel methods, is much needed. Read More

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Characterization of antibody response to an epitope spanning the haemagglutinin cleavage site of H7N9 subtype avian influenza virus for the differentiation of infected and vaccinated chickens.

Avian Pathol 2022 Apr 19:1-9. Epub 2022 Apr 19.

Joint International Research Laboratory of Agriculture and Agri-Product Safety, The Ministry of Education of China, Yangzhou University, Yangzhou, People's Republic of China.

H7N9 subtype avian influenza virus (AIV) is endemic in poultry in China, and vaccination is used as the primary strategy for disease control. However, by current serological tests, monitoring H7N9 virus infection in vaccinated poultry is difficult because vaccine-induced antibodies are not readily distinguishable from field viruses. Therefore, a test differentiating infected and vaccinated animals (DIVA) is critical for monitoring H7N9 virus. Read More

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Gizzard erosions in broiler chickens in Sweden caused by fowl adenovirus serotype 1 (FAdV-1): investigation of outbreaks, including whole-genome sequencing of an isolate.

Avian Pathol 2022 Apr 11:1-10. Epub 2022 Apr 11.

Department of Animal Health and Antimicrobial Strategies, National Veterinary Institute (SVA), Uppsala, Sweden.

The present paper describes the investigation of the first outbreaks of adenoviral gizzard erosions (AGE) in Sweden, in five broiler flocks. The investigation included whole viral genome sequencing and investigation of genomic organization and sequence relationships with other adenoviruses. All five flocks had a history of decreased growth and uneven size of birds since 9-10 days of age. Read More

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First detection of avian metapneumovirus subtype C Eurasian lineage in a Eurasian wigeon () wintering in Northeastern Italy: an additional hint on the role of migrating birds in the viral epidemiology.

Avian Pathol 2022 Mar 23:1-8. Epub 2022 Mar 23.

Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia, Italy.

Avian metapneumovirus (aMPV) economically affects the global poultry industry causing respiratory and reproductive disorders. Considering the paucity of data on aMPV occurrence in European free-ranging avifauna, a molecular survey was conducted on wild birds of 23 species belonging to the orders Anseriformes, Charadriiformes or Passeriformes, captured alive and sampled in Northeast Italy as part of the national avian influenza virus (AIV) surveillance activities. A total of 492 oropharyngeal swabs, collected from 2007-2010, all AIV-negative, were screened from aMPV by subtype-specific qRT-PCR. Read More

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Bone quality and composition are influenced by egg production, layer line, and oestradiol-17ß in laying hens.

Avian Pathol 2022 Apr 14:1-16. Epub 2022 Apr 14.

Institute of Animal Welfare and Animal Husbandry, Friedrich-Loeffler-Institut, Celle, Germany.

Keel bone fractures are a serious animal welfare problem in laying hens. The aim of the current study was to assess the influence of egg production, oestradiol-17ß, and selection for high laying performance on bone quality. Hens of two layer lines differing in laying performance (WLA: 320 eggs per year, G11: 200 eggs per year) were allocated to four treatment groups. Read More

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Point mutation revealed the resurgence of sub-genotype VII.2 Newcastle disease virus in Israel.

Avian Pathol 2022 Mar 2:1-8. Epub 2022 Mar 2.

The Poultry Health Laboratories, The Egg and Poultry Board, Kiryat Malachi, Israel.

RESEARCH HIGHLIGHTSIn 2019, there was a resurgence of NDV from sub-genotype VII.2 in Israel, in an already endemic area of sub-genotype VII.1. Read More

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Extracting turkey coronaviruses from the intestinal lumen of infected turkey embryos yields full genome data with good coverage by NGS.

Avian Pathol 2022 Mar 14:1-4. Epub 2022 Mar 14.

Agence National de Sécurité Sanitaire, de l'environnement et du travail (ANSES) laboratory of Ploufragan-Plouzané-Niort, Virology, immunology and parasitology in poultry and rabbit (VIPAC) Unit, Université de Rennes 1, Rennes, France.

Currently, turkey coronaviruses (TCoV) are isolated from homogenized intestines of experimentally infected embryos to ensure a maximum recovery of viral particles from all components of the intestines. However, the process of homogenization also ensures release of a significant amount of cellular RNAs into the sample that hinders downstream viral genome sequencing. This is especially the case for next generation sequencing (NGS) which sequences molecules at random. Read More

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Considerations for rapid development and licencing of conventional and platform technology veterinary vaccines.

Avian Pathol 2022 Apr 11;51(2):107-112. Epub 2022 Mar 11.

BioVacc Consulting Ltd, Amersham, UK.

The threat posed by zoonotic diseases and other livestock pathogens has never been greater, and thus we must do all we can to learn from experience in order to tackle emerging disease threats. The process of developing a new veterinary vaccine involves the generation of a specific set of data in order to meet the strict product licencing requirements of regulatory approval bodies around the globe. As a result, it is important that those embarking on the development of a vaccine using either conventional or novel platform technologies understand these regulations. Read More

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The inactivated infectious bronchitis virus (IBV) vaccine used as booster in layer hens influences the breadth of protection against challenge with IBV variants.

Avian Pathol 2022 Mar 7:1-13. Epub 2022 Mar 7.

MSD Animal Health/Intervet International BV, Boxmeer, The Netherlands.

To achieve long term protection of laying and breeding hens against aberrant egg production caused by infectious bronchitis virus (IBV), a vaccination programme incorporating both live-attenuated and inactivated IBV vaccines is required. High quality IBV vaccines of both types are widely available, but the number of IBV variants of global importance continues to increase and it is not possible to develop vaccines against each one of them. Therefore, it is desirable to perform studies under controlled conditions to determine which IBV vaccine(s) provide the best protection for laying hens against different IBV challenges. Read More

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Assessment of maternal immunity against serovar Heidelberg in progeny of broiler breeders vaccinated with different formulations of bacterins.

Avian Pathol 2022 Apr 3;51(2):197-205. Epub 2022 Mar 3.

Department of Preventive Veterinary Medicine, Veterinary School, Federal University of Minas Gerais (UFMG), Belo Horizonte, Brazil.

RESEARCH HIGHLIGHTSProgeny from vaccinated 30-week-old breeders presented less SH in caecal content compared to the control.High titres of maternal anti- IgY could be associated with lower SH faecal shedding. Read More

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Avian metapneumovirus subtype B vaccination in commercial broiler chicks: heterologous protection and selected host transcription responses to subtype A or B challenge.

Avian Pathol 2022 Apr 21;51(2):181-196. Epub 2022 Feb 21.

Institute of Infection and Global Health, University of Liverpool, Cheshire, UK.

Avian metapneumovirus (aMPV) causes respiratory disease and drops in egg production in chickens, and is routinely controlled by vaccination. However, the host's immune response to virulent challenge in vaccinated or unvaccinated broiler chickens is poorly characterized. We show that subtype B vaccination offers heterologous (subtype A challenge) and homologous (subtype B challenge) protection. Read More

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A Golden Anniversary for .

Damer P Blake

Avian Pathol 2022 Feb 31;51(1). Epub 2022 Jan 31.

Royal Veterinary College, Hawkshead Lane, North Mymms, Hertfordshire AL9 7TA, UK.

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February 2022

Epidemiological investigation of duck adenovirus 3 in southern China, during 2018-2020.

Avian Pathol 2022 Apr 17;51(2):171-180. Epub 2022 Feb 17.

Wen's Group Academy, Wen's Foodstuffs Group Co, Ltd, Yunfu, People's Republic of China.

RESEARCH HIGHLIGHTSFirst report of the epidemiology of duck adenovirus 3 infection in China.Mutant DAdV-3 strains (truncated ORF67) became predominant. Read More

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A multiplex real-time PCR assay for differential identification of avian .

Avian Pathol 2022 Apr 14;51(2):164-170. Epub 2022 Feb 14.

Avian Disease Research Division, Animal and Plant Quarantine Agency, Gimcheon-si, Korea.

Avian chlamydiosis is an acute or chronic disease of birds after infection by . Although is the primary agent of the disease, two additional species, and , have also been recognized as potential disease agents. Therefore, the diagnosis of avian chlamydiosis requires differential identification of these avian species. Read More

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Hcp2b of T6SS affects colonization of avian pathogenic and host keratin filament expression.

Avian Pathol 2022 Apr 28;51(2):154-163. Epub 2022 Feb 28.

Anhui Province Key Laboratory of Veterinary Pathobiology and Disease Control, College of Animal Science and Technology, Anhui Agricultural University, Hefei, PR People's Republic of China.

T6SS (type VI secretion system) is a type of nano-syringe that exists in APEC (avian pathogenic ). Hcp (haemolysin-coregulated protein) of T6SS participates in the regulation of virulence during APEC infection. However, whether plays a role in bacterial colonization by expression in host cells remains unclear. Read More

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Susceptibility of herons (family: ) to clade H5N1 subtype high pathogenicity avian influenza virus.

Avian Pathol 2022 Apr 25;51(2):146-153. Epub 2022 Jan 25.

Department of Joint Veterinary Medicine, Faculty of Agriculture, Tottori University, Tottori, Japan.

The pathogenicity of the H5 subtype high pathogenicity avian influenza viruses (HPAIVs) in bird species has not been investigated yet despite the increasing infections reported. Therefore, the present study aimed to examine the susceptibility of the species, which had already been reported to be susceptible to HPAIVs, to a clade 2.3. Read More

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A preliminary study of the localization of infectious laryngotracheitis virus glycoprotein E within specific peripheral blood lymphocytes.

Avian Pathol 2022 Apr 19;51(2):141-145. Epub 2022 Jan 19.

Animal Science, School of Environmental and Rural Science, University of New England, Armidale, Australia.

Infectious laryngotracheitis virus (ILTV) DNA has been detected in blood fractions, but the cell phenotype with which the virus is associated is unknown. This study investigated the presence of ILTV antigen in peripheral blood cells of six acutely ILTV-infected chickens (5 or 9 days post ocular inoculation with a virulent isolate) and three sham-inoculated chickens using immunofluorescent staining. Blood fractions were separated by Ficoll-Paque density gradient centrifugation, and smears were prepared from erythrocyte and leukocyte fractions. Read More

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The association of ribosomal protein L18 with Newcastle disease virus matrix protein enhances viral translation and replication.

Avian Pathol 2022 Apr 25;51(2):129-140. Epub 2022 Jan 25.

Key Laboratory of Animal Genetics, Breeding and Reproduction in the Plateau Mountainous Region, Ministry of Education, Guizhou University, Guiyang, People's Republic of China.

Numerous studies have shown that viruses can utilize or manipulate ribosomal proteins to achieve viral protein biosynthesis and replication. In our recent studies using proteomics analysis of virus-infected cells, we found that ribosomal protein L18 (RPL18) was the highest up-regulated differentially expressed protein, along with the increasingly expressed viral proteins later in Newcastle disease virus (NDV) infection. However, the association of RPL18 with viral protein biosynthesis and NDV replication remains unclear. Read More

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Combining pangenome analysis to identify potential cross-protective antigens against avian pathogenic .

Avian Pathol 2022 Feb 31;51(1):66-75. Epub 2022 Jan 31.

College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People's Republic of China.

RESEARCH HIGHLIGHTSPan-RV analysis was used for the first time in the discovery of APEC-protective proteins.A total of 53 potential protective proteins were screened out.Four proteins were verified as potential vaccine candidates using western blotting. Read More

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February 2022

Comparative pathogenicity of Malaysian variant and very virulent infectious bursal disease viruses in chickens.

Avian Pathol 2022 Feb;51(1):76-86

Department of Veterinary Clinical Studies, Faculty of Veterinary Medicine, Universiti Putra Malaysia Serdang, Malaysia.

Variant infectious bursal disease virus (vaIBDV) has been identified in various countries with significant economic losses. Recently, the first identification of a variant strain in Malaysia was reported. The pathogenicities of the Malaysian variant, UPM1432/2019, and very virulent infectious bursal disease virus (vvIBDV), UPM1056/2018 strains were comparatively evaluated in specific-pathogen-free (SPF) chickens based on gross and histopathological examinations and viral load. Read More

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February 2022

Detection and molecular characterization of a new genotype of infectious bursal disease virus in Portugal.

Avian Pathol 2022 Feb 14;51(1):97-105. Epub 2021 Dec 14.

Department of Animal Medicine, Production and Health, University of Padua, Legnaro (PD), Italy.

RESEARCH HIGHLIGHTSEight IBDV strains with unique VP2 features were detected in Portugal.Based on two distinct classification methods, the strains belong to a new genotype. Read More

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February 2022

Retroviral association with ovarian adenocarcinoma in laying hens.

Avian Pathol 2022 Apr 31;51(2):113-119. Epub 2022 Jan 31.

Department of Veterinary Clinical Medicine, University of Illinois, Urbana, IL, USA.

The laying hen has been used as a model for ovarian adenocarcinoma (OAC) in women. Previous work has shown an association between expression of endogenous retroviral proteins and elevated envelope mRNA and occurrence of OAC in humans, but causality has not been demonstrated. The objective of this study was to determine whether there is a similar association between retrovirus presence and OAC in a commercial laying hen flock at the University of Illinois Poultry Research facility with a history of a high OAC prevalence in older hens. Read More

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Short-term and long-term effects of antimicrobial use on antimicrobial resistance in broiler and turkey farms.

Avian Pathol 2022 Apr 20;51(2):120-128. Epub 2022 Jan 20.

Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro (PD), Italy.

RESEARCH HIGHLIGHTSSulfamethoxazole and ampicillin resistance are the highest in isolates of both broilers and turkeys.Short-term effects of antibiotic use on resistance are seen more often than long-term effects.Historical penicillin use is associated with penicillin resistance in broilers. Read More

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