8,672 results match your criteria Avian Flu


Continuing evolution of highly pathogenic H5N1 viruses in Bangladeshi live poultry markets.

Emerg Microbes Infect 2019 ;8(1):650-661

b Department of Zoology , Jahangirnagar University , Dhaka , Bangladesh.

Since November 2008, we have conducted active avian influenza surveillance in Bangladesh. Clades 2.2. Read More

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http://dx.doi.org/10.1080/22221751.2019.1605845DOI Listing
January 2019

Farm products' direct sale in accordance with national and EC Regulations.

Ital J Food Saf 2019 Mar 22;8(1):7119. Epub 2019 Mar 22.

Local Sanitary Authority of Modena.

Primary production has always been considered the weak link in the entire food production chain () and, due also to the grave health and food emergencies that have taken place over the years (BSE, dioxin, avian flu etc.), greater attention has been focused on the production stage, together with the need to regain the consumers' faith. To preserve and support small farms in a local setting and, consistent with the aims of flexibility and respecting the main requisites contained in the EC Regulations (No. Read More

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http://dx.doi.org/10.4081/ijfs.2019.7119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452099PMC
March 2019
1 Read

Contrasting effects of host species and phylogenetic diversity on the occurrence of HPAI H5N1 in European wild birds.

J Anim Ecol 2019 Apr 19. Epub 2019 Apr 19.

Resource Ecology Group, Wageningen University, 6708PB, Wageningen, The Netherlands.

Studies on the highly pathogenic avian influenza (HPAI) H5N1 suggest that wild bird migration may facilitate its long-distance spread, yet the role of wild bird community composition in its transmission risk remains poorly understood. Furthermore, most studies on the diversity-disease relationship focused on host species diversity without considering hosts' phylogenetic relationships, which may lead to rejecting a species diversity effect when the community has host species that are only distantly related. Here, we explored the influence of waterbird community composition for determining HPAI H5N1 occurrence in wild birds in a continental-scale study across Europe. Read More

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http://dx.doi.org/10.1111/1365-2656.12997DOI Listing

Aerosol Transmission of Gull-Origin Iceland Subtype H10N7 Influenza A Virus in Ferrets.

J Virol 2019 Apr 17. Epub 2019 Apr 17.

Department of Basic Science, College of Veterinary Medicine, Mississippi State University, Mississippi, United States

Subtype H10 influenza A viruses (IAVs) have been recovered from domestic poultry and various aquatic bird species, and sporadic transmission of these IAVs from avian species to mammals (i.e., human, seal, and mink) are well documented. Read More

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http://jvi.asm.org/lookup/doi/10.1128/JVI.00282-19
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http://dx.doi.org/10.1128/JVI.00282-19DOI Listing
April 2019
5 Reads

Immunosuppressive potential of fowl adenovirus serotype 4.

Poult Sci 2019 Apr 16. Epub 2019 Apr 16.

College of Animal Science and Technology, Shandong Agricultural University, Tai'an, Shandong Province 271018, China.

Fowl adenovirus serotype 4 (FAdV-4) is the causative agent of hydropericardium syndrome. To clarify the effects of FAdV-4 on immune organs in birds, we conducted a detailed examination of dynamic morphology and damage mechanisms in chickens randomly divided into 4 groups (FAdV-4, vaccination, FAdV-4 plus vaccination, and control). FAdV-4 caused the depletion of lymphocytes and subsequent growth impairment in the thymus and bursa. Read More

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https://academic.oup.com/ps/advance-article/doi/10.3382/ps/p
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http://dx.doi.org/10.3382/ps/pez179DOI Listing
April 2019
2 Reads

Subclade 2.2.1-Specific Human Monoclonal Antibodies That Recognize an Epitope in Antigenic Site A of Influenza A(H5) Virus HA Detected between 2015 and 2018.

Viruses 2019 Apr 2;11(4). Epub 2019 Apr 2.

Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Minato-ku, Tokyo 108-8639, Japan.

Highly pathogenic avian H5 influenza viruses persist among poultry and wild birds throughout the world. They sometimes cause interspecies transmission between avian and mammalian hosts. H5 viruses possessing the HA of subclade 2. Read More

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http://dx.doi.org/10.3390/v11040321DOI Listing
April 2019
1 Read

Ducks induce rapid and robust antibody responses than chickens at early time after intravenous infection with H9N2 avian influenza virus.

Virol J 2019 04 11;16(1):46. Epub 2019 Apr 11.

Innovation Team for Pathogen Ecology Research on Animal Influenza Virus, and Department of Avian Infectious Disease, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, People's Republic of China.

Background: Compared with chickens, ducks are normally resistant to avian influenza virus without clinical signs while they habor almost all subtypes of influenza A viruses. To date, however the mechanism for duck anti-influenza has not been completely understood. The H9N2 avian influenza virus (AIV) is the most prevalent subtype of influenza A virus that infects chickens and ducks in China. Read More

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http://dx.doi.org/10.1186/s12985-019-1150-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460658PMC
April 2019
1 Read

A two-year prospective study of small poultry flocks in Ontario, Canada, part 1: prevalence of viral and bacterial pathogens.

J Vet Diagn Invest 2019 Apr 11:1040638719843577. Epub 2019 Apr 11.

Departments of Pathobiology (Brochu, Lillie, Susta).

In Ontario, within the past few years, there has been a marked increase in the number of non-commercial poultry flocks (referred to as "small flocks"). Small poultry flocks may act as a reservoir of avian and zoonotic pathogens, given the flocks' limited access to veterinary services, inadequate biosecurity practices, and increased risk of contact with wild birds. Despite these potential risks, there is a scarcity of data concerning the prevalence of poultry and zoonotic pathogens among these flocks. Read More

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http://dx.doi.org/10.1177/1040638719843577DOI Listing
April 2019
1 Read

Infections and pathology of free-roaming backyard chickens on St. Kitts, West Indies.

J Vet Diagn Invest 2019 Apr 11:1040638719843638. Epub 2019 Apr 11.

Departments of Biomedical Sciences (Bolfa, Callanan, Ketzis, Marchi, Cheng, Huynh, Lavinder, Boey).

Free-roaming chickens on Caribbean islands are important sentinels for local avian diseases and those introduced by birds migrating through the Americas. We studied 81 apparently healthy unvaccinated free-roaming chickens from 9 parishes on St. Kitts, an eastern Caribbean island. Read More

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http://journals.sagepub.com/doi/10.1177/1040638719843638
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http://dx.doi.org/10.1177/1040638719843638DOI Listing
April 2019
3 Reads

Genetic analysis identifies potential transmission of low pathogenic avian influenza viruses between poultry farms.

Transbound Emerg Dis 2019 Apr 9. Epub 2019 Apr 9.

Department of Virology, Wageningen Bioveterinary Research, Lelystad, The Netherlands.

Poultry can become infected with low pathogenic avian influenza (LPAI) viruses via (in)direct contact with infected wild birds, or by transmission of the virus between farms. This study combines routinely collected surveillance data with genetic analysis to assess the contribution of between-farm transmission to the overall incidence of LPAI virus infections in poultry. Over a ten-year surveillance period, we identified 35 potential cases of between-farm transmission in the Netherlands, of which ten formed geographical clusters. Read More

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http://dx.doi.org/10.1111/tbed.13199DOI Listing
April 2019
1 Read

Influenza A viruses in birds and humans: Prevalence, molecular characterization, zoonotic significance and risk factors' assessment in poultry farms.

Comp Immunol Microbiol Infect Dis 2019 Apr 9;63:51-57. Epub 2019 Jan 9.

Department of Virology, Faculty of Veterinary Medicine, Zagazig University, 44511, Zagazig, Egypt.

This study aimed to investigate the prevalence of influenza A viruses in birds and humans residing in the same localities of Sharkia Province, Egypt and the risk factors' assessment in poultry farms. A total of 100 birds comprised of 50 chickens, 25 ducks and 25 wild egrets were sampled. Swab samples were collected from 65 people (50 poultry farm workers and 15 hospitalized patients). Read More

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http://dx.doi.org/10.1016/j.cimid.2019.01.001DOI Listing
April 2019
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Meta-transcriptomics reveals a diverse antibiotic resistance gene pool in avian microbiomes.

BMC Biol 2019 Apr 8;17(1):31. Epub 2019 Apr 8.

Marie Bashir Institute for Infectious Diseases and Biosecurity and Sydney Medical School, The University of Sydney, Sydney, NSW, 2006, Australia.

Background: Antibiotic resistance is rendering common bacterial infections untreatable. Wildlife can incorporate and disperse antibiotic-resistant bacteria in the environment, such as water systems, which in turn serve as reservoirs of resistance genes for human pathogens. Anthropogenic activity may contribute to the spread of bacterial resistance cycling through natural environments, including through the release of human waste, as sewage treatment only partially removes antibiotic-resistant bacteria. Read More

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https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-01
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http://dx.doi.org/10.1186/s12915-019-0649-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454771PMC
April 2019
4 Reads

Protection Afforded By Avian Influenza Vaccination Programs Consisting Of A Novel RNA Particle And An Inactivated Avian Influenza Vaccine Against A Highly Pathogenic Avian Influenza Virus Challenge In Layer Chickens Up To 18 Weeks Post Vaccination.

Avian Pathol 2019 Apr 9:1-34. Epub 2019 Apr 9.

b Southeast Poultry Research Laboratory, US National Poultry Research Center, U.S. Department of Agriculture , Agricultural Research Service (ARS) , 934 College Station Rd., Athens , GA 30605.

The efficacies of an oil adjuvanted-inactivated reverse genetics derived H5 avian influenza virus (AIV) vaccine and an alphavirus replicon RNA particle (RP) AIV vaccine were evaluated in commercial leghorn chickens. Challenge utilized A/Turkey/MN/12582/2015, an isolate representing the U.S. Read More

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http://dx.doi.org/10.1080/03079457.2019.1605148DOI Listing
April 2019
1 Read

Application of Deep-Learning Methods to Bird Detection Using Unmanned Aerial Vehicle Imagery.

Sensors (Basel) 2019 Apr 6;19(7). Epub 2019 Apr 6.

Department of Biosystems and Biomaterials Science and Engineering, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Korea.

Wild birds are monitored with the important objectives of identifying their habitats and estimating the size of their populations. Especially in the case of migratory bird, they are significantly recorded during specific periods of time to forecast any possible spread of animal disease such as avian influenza. This study led to the construction of deep-learning-based object-detection models with the aid of aerial photographs collected by an unmanned aerial vehicle (UAV). Read More

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http://dx.doi.org/10.3390/s19071651DOI Listing
April 2019
1 Read

Immunological and pathological effects of vitamin E with Fetomune Plus on chickens experimentally infected with avian influenza virus H9N2.

Vet Microbiol 2019 Apr 20;231:24-32. Epub 2019 Feb 20.

Department of Pathology, Animal Health Research Institute, Mansoura branch, Egypt.

Avian influenza virus (AIV) H9N2 infection causes economic losses on poultry farms, and immunostimulants are essential for improving chicken immunity. This study evaluated the immunological and pathological effects of vitamin E with Fetomune Plus (a commercial product based on a yeast extract and vitamins) on chickens experimentally infected with AIV H9N2. Three groups of white Hy-Line chicks were included. Read More

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http://dx.doi.org/10.1016/j.vetmic.2019.02.028DOI Listing
April 2019
2 Reads

Clinical evaluation of multiplex RT-PCR assays for the detection of influenza A/B and respiratory syncytial virus using a high throughput system.

J Virol Methods 2019 Apr 1;269:49-54. Epub 2019 Apr 1.

University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.

Background: Lower respiratory tract infections are a major threat to public health systems worldwide, with RSV and influenza being the main agents causing hospitalization. In outbreak situations, high-volume respiratory testing is needed. In this study, we evaluated the analytical and clinical performance of a pre-designed primer/probe set for the simultaneous multiplex detection of both viruses on a high-throughput platform, the cobas 6800, using the "open channel" of the system for integration of lab-developed assays for the detection of influenza and RSV. Read More

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http://dx.doi.org/10.1016/j.jviromet.2019.03.015DOI Listing
April 2019
3 Reads

H7N6 low pathogenic avian influenza outbreak in commercial turkey farms in Chile caused by a native South American Lineage.

Transbound Emerg Dis 2019 Apr 4. Epub 2019 Apr 4.

The ithree Institute, University of Technology Sydney, Sydney, New South Wales, Australia.

In December 2016, low pathogenic avian influenza (LPAI) caused by an H7N6 subtype was confirmed in a grow-out turkey farm located in Valparaiso Region, Chile. Depopulation of exposed animals, zoning, animal movement control and active surveillance were implemented to contain the outbreak. Two weeks later, a second grow-out turkey farm located 70 km north of the first site was also infected by H7N6 LPAI, which subsequently spilled over to one backyard poultry flock. Read More

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http://dx.doi.org/10.1111/tbed.13166DOI Listing

Characterization of three clade 2.3.4.4 H5 highly pathogenic avian influenza viruses isolated from wild birds.

J Infect 2019 Mar 27. Epub 2019 Mar 27.

Guangdong Institute of Applied Biological Resources, Guangzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.jinf.2019.03.011DOI Listing
March 2019
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H9N2 Viruses Isolated From Mammals Replicated in Mice at Higher Levels Than Avian-Origin Viruses.

Front Microbiol 2019 11;10:416. Epub 2019 Mar 11.

Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.

H9N2 subtype influenza A virus (IAV) has more than 20 genotypes that are able to cross species barriers and expand from birds to mammals and humans. To better understand the impact of different H9N2 genotypes and their characteristics, five H9N2 viruses from different hosts including chickens, geese, pigs, mink, and humans representing the B69 88(Gs/14, Ck/15, and Mi/14), B35 (Sw/08) and G9 genotypes (Hu/04) were infected in chicken and mice. In mice, mammal-origin viruses replicated at higher levels in the lungs compared to avian viruses. Read More

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http://dx.doi.org/10.3389/fmicb.2019.00416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421276PMC
March 2019
2 Reads

A computationally designed H5 antigen shows immunological breadth of coverage and protects against drifting avian strains.

Vaccine 2019 Apr 21;37(17):2369-2376. Epub 2019 Mar 21.

Sanofi-Pasteur, 38 Sidney Street, Cambridge, MA 02139, USA.

Since the first identification of the H5N1 Goose/Guangdong lineage in 1996, this highly pathogenic avian influenza virus has spread worldwide, becoming endemic in domestic poultry. Sporadic transmission to humans has raised concerns of a potential pandemic and underscores the need for a broad cross-protective influenza vaccine. Here, we tested our previously described methodology, termed Computationally Optimized Broadly Reactive Antigen (COBRA), to generate a novel hemagglutinin (HA) gene, termed COBRA-2, that was based on H5 HA sequences from 2005 to 2006. Read More

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http://dx.doi.org/10.1016/j.vaccine.2019.03.018DOI Listing
April 2019
2 Reads

Isolation and characterization of a novel H7N8 avian influenza virus from domestic ducks in Central China in 2017.

Virus Genes 2019 Mar 20. Epub 2019 Mar 20.

China Animal Health and Epidemiology Center, Qingdao, China.

In 2017, an H7N8 avian influenza virus (AIV) was isolated from a domestic duck from a farm in Central China. Sequences analysis showed that this strain received its genes from H7, H1, H2, H3, H5, and H6 AIVs of domestic poultry and wild birds in Asia. It exhibited low pathogenicity in chickens and mild pathogenicity in mice. Read More

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http://link.springer.com/10.1007/s11262-018-01630-2
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http://dx.doi.org/10.1007/s11262-018-01630-2DOI Listing
March 2019
7 Reads

Effects of cage size on growth performance, blood biochemistry, and antibody response in layer breeder males during rearing stage.

Poult Sci 2019 Mar 20. Epub 2019 Mar 20.

Institute of Animal Husbandry and Veterinary Medicine, Anhui Academy of Agricultural Science, Anhui Province Key Laboratory of Livestock and Poultry Product Safety Engineering, Hefei 230031, China.

This study was conducted to investigate the effects of cage size on growth performance, blood biochemistry, and antibody response in layer breeder males during rearing stage. 575 one-day-old Jinghong layer breeder males were randomly allocated into 3 treatments and reared in 3 cage sizes: large (160 × 160 × 62 cm; LC), medium (120 × 120 × 62 cm; MC), and small (80 × 70 × 62 cm; SC). The stocking density of birds in 3 treatments was kept identical and adjusted every 2 wk, from 45 birds/m2 during the period of 0 to 2 wk of age to 12 birds/m2 during the period of 17 to 18 wk of age. Read More

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http://dx.doi.org/10.3382/ps/pez102DOI Listing
March 2019
1 Read

Antarctic penguins as reservoirs of diversity for avian avulaviruses.

J Virol 2019 Mar 20. Epub 2019 Mar 20.

WHO Collaborating Centre for Reference and Research on Influenza, at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia

Wild birds harbour a huge diversity of avian avulaviruses (formerly avian paramyxoviruses). Antarctic penguin species have been screened for avian avulaviruses since the 1980s, and as such are known hosts of these viruses. In this study we screened three penguin species from the South Shetland Islands and the Antarctic Peninsula for avian avulaviruses. Read More

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http://dx.doi.org/10.1128/JVI.00271-19DOI Listing
March 2019
2 Reads

Efficacy of novel recombinant fowlpox vaccine against recent Mexican H7N3 highly pathogenic avian influenza virus.

Vaccine 2019 Apr 15;37(16):2232-2243. Epub 2019 Mar 15.

Exotic and Emerging Avian Viral Diseases Research Unit, Southeast Poultry Research Laboratory, U.S. National Poultry Research Center, Agricultural Research Service, U.S. Department of Agriculture, Athens, GA, USA. Electronic address:

Since 2012, H7N3 highly pathogenic avian influenza (HPAI) has produced negative economic and animal welfare impacts on poultry in central Mexico. In the present study, chickens were vaccinated with two different recombinant fowlpox virus vaccines (rFPV-H7/3002 with 2015 H7 hemagglutinin [HA] gene insert, and rFPV-H7/2155 with 2002 H7 HA gene insert), and were then challenged three weeks later with H7N3 HPAI virus (A/chicken/Jalisco/CPA-37905/2015). The rFPV-H7/3002 vaccine conferred 100% protection against mortality and morbidity, and significantly reduced virus shed titers from the respiratory and gastrointestinal tracts. Read More

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http://dx.doi.org/10.1016/j.vaccine.2019.03.009DOI Listing
April 2019
4 Reads

Intranasally administered polyethylenimine adjuvanted influenza M2 ectodomain induces partial protection against H9N2 influenza A virus infection in chickens.

Vet Immunol Immunopathol 2019 Mar 4;209:78-83. Epub 2019 Mar 4.

College of Veterinary Medicine, Chonbuk National University, Iksan, 54596, Republic of Korea. Electronic address:

This study aimed to investigate whether intranasally coadministered four tandem copies of extracellular domains of M2 (M2e) and polyethyleneimine (PEI), a mucosal adjuvant, can protect chickens against H9N2 influenza A virus infection. Groups of chickens were intranasally vaccinated with M2e plus PEI adjuvant, M2e alone or PEI adjuvant, and antibody (serum IgG and mucosal IgA) and cellular (CD4 T cells and IFN-γ levels) immune responses were measured post-vaccination. We demonstrated that the chickens vaccinated with M2e plus PEI adjuvant showed significantly (p < 0. Read More

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http://dx.doi.org/10.1016/j.vetimm.2019.02.007DOI Listing
March 2019
1 Read

Isolation of H8N4 avian influenza virus from wild birds in Shanghai, China.

Acta Virol 2019;63(1):121-125

The H8 subtype viruses are rarely isolated from wild ducks. Shanghai is one of the important wintering or stopover sites on the East Asia-Australia Migration Flyway. An influenza virus, subtype H8N4, was firstly isolated from a common teal (Anas crecca) in Shanghai during 2017-2018 in this study. Read More

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http://dx.doi.org/10.4149/av_2019_116DOI Listing
January 2019
1 Read

Genetic relationship between poultry and wild bird viruses during the highly pathogenic avian influenza H5N6 epidemic in the Netherlands, 2017-2018.

Transbound Emerg Dis 2019 Mar 15. Epub 2019 Mar 15.

Wageningen Bioveterinary Research, Lelystad, the Netherlands.

In the Netherlands, three commercial poultry farms and two hobby holdings were infected with highly pathogenic avian influenza (HPAI) H5N6 virus in the winter of 2017-2018. This H5N6 virus is a reassortant of HPAI H5N8 clade 2.3. Read More

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http://dx.doi.org/10.1111/tbed.13169DOI Listing
March 2019
1 Read

Cross-reactive antibodies binding to H4 hemagglutinin protect against a lethal H4N6 influenza virus challenge in the mouse model.

Emerg Microbes Infect 2019 ;8(1):155-168

a Department of Microbiology , Icahn School of Medicine at Mount Sinai , New York , NY , USA.

Influenza viruses of the H4 subtype are widespread in wild birds, circulate in domestic poultry, readily infect mammals, and tolerate the insertion of a polybasic cleavage site. In addition, serological evidence suggests that humans working with poultry are exposed to these viruses. While H4 viruses are not of immediate pandemic concern, there is a lack of knowledge regarding their antigenicity. Read More

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http://dx.doi.org/10.1080/22221751.2018.1564369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455122PMC
January 2019
2 Reads

Survivability of highly pathogenic avian influenza virus (H5N1) in naturally preened duck feathers at different temperatures.

Transbound Emerg Dis 2019 Mar 12. Epub 2019 Mar 12.

Division of Bacteriology and Mycology, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, India.

Ducks are the "Trojan Horses" for Asian H5N1 avian influenza viruses (AIV) and attain carrier status without displaying overt infection. These birds help in the spread of the virus among the poultry and human population through direct or indirect contact. Preen oil is the secretion of preen gland of water birds such as ducks. Read More

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http://dx.doi.org/10.1111/tbed.13148DOI Listing
March 2019
6 Reads
2.944 Impact Factor

Modelling the impact of biosecurity practices on the risk of high pathogenic avian influenza outbreaks in Australian commercial chicken farms.

Prev Vet Med 2019 Apr 5;165:8-14. Epub 2019 Feb 5.

School of Animal and Veterinary Sciences and Graham Centre for Agricultural Innovation, Charles Sturt University, Australia.

As of 2018, Australia has experienced seven outbreaks of highly pathogenic avian influenza (HPAI) in poultry since 1976, all of which involved chickens. There is concern that increases in free-range farming could heighten HPAI outbreak risk due to the potential for greater contact between chickens and wild birds that are known to carry low pathogenic avian influenza (LPAI). We use mathematical models to assess the effect of a shift to free-range farming on the risk of HPAI outbreaks of H5 or H7 in the Australian commercial chicken industry, and the potential for intervention strategies to reduce this risk. Read More

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http://dx.doi.org/10.1016/j.prevetmed.2019.02.002DOI Listing
April 2019
1 Read

A modified TOPSIS (Technique for Order of Preference by Similarity to Ideal Solution) applied to choosing appropriate selection methods in ongoing surveillance for Avian Influenza in Canada.

Prev Vet Med 2019 Apr 10;165:36-43. Epub 2019 Feb 10.

Terrestrial Animal Health Epidemiology and Surveillance Section, Canadian Food Inspection Agency, 3200 Sicotte St., P.O. Box 5000, St-Hyacinthe, QC, J2S 7C6, Canada.

To achieve an appropriate and efficient sample in a surveillance program, the goals of the program should drive a careful consideration of the selection method or combination of selection methods to be applied. Therefore, the ongoing analysis and assessment of a surveillance system may include an assessment of the ability of the applied selection methods to generate an appropriate sample. There may be opinions from many technical experts (TEs) and many criteria to consider in a surveillance system so there is a need for methods to combine knowledge, priorities and preferences from a group of TEs. Read More

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http://dx.doi.org/10.1016/j.prevetmed.2019.02.006DOI Listing
April 2019
1 Read

Two novel reassortant H11N8 avian influenza viruses occur in wild birds found in East Dongting Lake, China.

Arch Virol 2019 May 8;164(5):1405-1410. Epub 2019 Mar 8.

School of Life Sciences, East China Normal University, Shanghai, 200062, China.

During the surveillance of avian influenza viruses in East Dongting Lake, China (2014-2015), two H11N8 avian influenza viruses were detected in the bean goose (Anser fabalis) and the falcated teal (Anas falcata). Phylogenetic analysis showed that these two novel reassortant H11N8 avian influenza viruses contain genes from poultry and wild birds. This is the first report detecting the H11N8 subtype influenza virus from wild birds in Asia. Read More

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http://dx.doi.org/10.1007/s00705-019-04168-2DOI Listing
May 2019
1 Read

Transmission dynamics and control strategies assessment of avian influenza A (H5N6) in the Philippines.

Infect Dis Model 2018 16;3:35-59. Epub 2018 Mar 16.

Mathematics & Statistics Department, De La Salle University, 2401 Taft Avenue, 0922 Manila, Philippines.

Due to the outbreaks of Highly Pathogenic Avian Influenza A (HPAI) H5N6 in the Philippines (particularly in Pampanga and Nueva Ecija) in August 2017, there has been an increase in the need to cull the domestic birds to control the spread of the infection. However, this control method poses a negative impact on the poultry industry. In addition, the pathogenicity and transmissibility of the H5N6 in both the birds and the humans remain largely unknown which call for the necessity to develop more strategic control methods for the virus. Read More

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http://dx.doi.org/10.1016/j.idm.2018.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326262PMC
March 2018
1 Read

Diet May Drive Influenza A Virus Exposure in African Mammals.

J Infect Dis 2019 Mar 6. Epub 2019 Mar 6.

Department of Wildlife Diseases, Leibniz Institute for Zoo and Wildlife Research, Berlin.

Background: Influenza A viruses (IAVs) represent repeatedly emerging pathogens with near worldwide distribution and an unclear nonavian-host spectrum. While the natural hosts for IAV are among waterfowl species, certain mammals can be productively infected. Southern Africa is home to diverse avian and mammalian fauna for which almost no information exists on IAV dynamics. Read More

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http://dx.doi.org/10.1093/infdis/jiz032DOI Listing
March 2019
6 Reads

Chicken anaemia virus enhances and prolongs subsequent avian influenza (H9N2) and infectious bronchitis viral infections.

Vet Microbiol 2019 Mar 2;230:123-129. Epub 2019 Feb 2.

National Laboratory for Veterinary Quality Control on Poultry Production, Animal Health Research Institute, Giza, 12618, Egypt; Zoonosis Science Center, Department of Medical Biochemistry and Microbiology, Uppsala University, 751 21, Uppsala, Sweden. Electronic address:

Immunosuppressive viral diseases have a great economic importance in the poultry industry due to the increased susceptibility to secondary infections. Chicken anaemia virus (CAV) is one of the major immunosuppressive diseases in chickens. In addition, low pathogenic avian influenza (LPAI) of subtype H9N2 and infectious bronchitis (IB) viruses are among the most frequently reported respiratory viral diseases in poultry worldwide. Read More

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http://dx.doi.org/10.1016/j.vetmic.2019.01.024DOI Listing
March 2019
6 Reads

Modelling high pathogenic avian influenza outbreaks in the commercial poultry industry.

Theor Popul Biol 2019 04 27;126:59-71. Epub 2019 Feb 27.

Research School of Population Health, Australian National University, Canberra, Australia.

Highly pathogenic avian influenza (HPAI) outbreaks are devastating to poultry industries and pose a risk to human health. There is concern that demand for free-range poultry products could increase the number of HPAI outbreaks by increasing the potential for low pathogenic avian influenza (LPAI) introduction to commercial flocks. We formulate stochastic mathematical models to understand how poultry-housing (barn, free-range and caged) within the meat and layer sectors interacts with a continuous low-level risk of introduction from wild birds, heterogeneity in virus transmission rates and virus mutation probabilities, to affect the risk of HPAI emergence - at both the shed and industry scales. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00405809183017
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http://dx.doi.org/10.1016/j.tpb.2019.02.004DOI Listing
April 2019
3 Reads

Study of the underlying mechanisms and consequences of pathogenicity differences between two in vitro selected G1-H9N2 clones originating from a single isolate.

Vet Res 2019 Mar 1;50(1):18. Epub 2019 Mar 1.

Avian Virology and Immunology Service, National Reference Laboratory for Avian Influenza and Newcastle Disease Virus, Sciensano, Uccle, Brussels, Belgium.

The G1-H9N2 avian influenza virus (AIV) has caused significant economic losses in the commercial poultry industry due to reduced egg production and increased mortality. The field observations have shown that H9N2 viruses circulate and naturally mix with other pathogens and these simultaneous infections can exacerbate disease. To avoid an incorrect virus characterization, due to co-infection, isolates were purified by in vitro plaque assays. Read More

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http://dx.doi.org/10.1186/s13567-019-0635-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397504PMC
March 2019
2 Reads

Avian influenza viruses at the wild-domestic bird interface in Egypt.

Infect Ecol Epidemiol 2019 20;9(1):1575687. Epub 2019 Feb 20.

Zoonosis Science Center, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.

Wild birds of the orders Anseriforme (mainly ducks, geese and swans) and Charadriiformes (mainly gulls, terns and waders) constitute the natural reservoir for low pathogenic avian influenza (LPAI) viruses. In Egypt, highly pathogenic avian influenza (HPAI) H5N1 and LPAI H9N2 viruses are endemic in domestic poultry, forming a threat to animal and human health and raising questions about the routes of introduction and mechanisms of persistence. Recently, HPAI H5N8 virus was also introduced into Egyptian domestic birds. Read More

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http://dx.doi.org/10.1080/20008686.2019.1575687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383604PMC
February 2019
3 Reads

Zoonotic diseases from birds to humans in Vietnam: possible diseases and their associated risk factors.

Eur J Clin Microbiol Infect Dis 2019 Feb 26. Epub 2019 Feb 26.

School of Odonto Stomatology, Hanoi Medical University, Hanoi, Vietnam.

In recent decades, exceeding 60% of infectious cases in human beings are originated from pathogenic agents related to feral or companion animals. This figure continues to swiftly increase due to excessive exposure between human and contaminated hosts by means of applying unhygienic farming practices throughout society. In Asia countries-renowned for lax regulation towards animal-trading markets-have experienced tremendous outbreaks of zoonotic diseases every year. Read More

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http://dx.doi.org/10.1007/s10096-019-03505-2DOI Listing
February 2019
2 Reads
2.668 Impact Factor

Multiplex one-step real-time PCR assay for rapid simultaneous detection of velogenic and mesogenic Newcastle disease virus and H5-subtype avian influenza virus.

Arch Virol 2019 Apr 21;164(4):1111-1119. Epub 2019 Feb 21.

Animal Infectious Disease Laboratory, School of Veterinary Medicine, Yangzhou University, 48 East Wenhui Road, Yangzhou, Jiangsu, China.

H5 avian influenza virus (AIV) and velogenic Newcastle disease virus (v-NDV) are pathogens listed in the OIE Terrestrial Animal Health Code and are considered key pathogens to be eliminated in poultry production. Molecular techniques for rapid detection of H5 AIV and v-NDV are required to investigate their transmission characteristics and to guide prevention. Traditional virus isolation, using embryonated chicken eggs, is time-consuming and cannot be used as a rapid diagnostic technology. Read More

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http://dx.doi.org/10.1007/s00705-019-04180-6DOI Listing
April 2019
1 Read

Human exposures to H5N6 Avian influenza, England, 2018.

J Infect Dis 2019 Feb 21. Epub 2019 Feb 21.

National Infection Service, Public Health England, London, UK.

The human risk following exposure to the European reassortant avian influenza A (H5N6) is unknown. We used routine data collected as part of public health follow-up to assess outcomes of individuals exposed to H5N6 infected wild birds in England. There were 19 separate incidents of confirmed H5N6 among wild birds in the first quarter of 2018 in England and 69 individuals exposed to infected birds during these incidents. Read More

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http://dx.doi.org/10.1093/infdis/jiz080DOI Listing
February 2019
2 Reads

Viral infection detection using metagenomics technology in six poultry farms of eastern China.

PLoS One 2019 20;14(2):e0211553. Epub 2019 Feb 20.

China Animal Health and Epidemiology Center, Qingdao, Shandong, China.

With rapidly increasing animal pathogen surveillance requirements, new technologies are needed for a comprehensive understanding of the roles of pathogens in the occurrence and development of animal diseases. We applied metagenomic technology to avian virus surveillance to study the main viruses infecting six poultry farms in two provinces in eastern China. Cloacal/throat double swabs were collected from 60 birds at each farm according to a random sampling method. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0211553PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382132PMC
February 2019
14 Reads

Pathogenicity and Transmissibility of North American H7 Low Pathogenic Avian Influenza Viruses in Chickens and Turkeys.

Viruses 2019 Feb 16;11(2). Epub 2019 Feb 16.

VA-MD Regional College of Veterinary Medicine, University of Maryland, College Park, MD 20742, USA.

Low pathogenic avian influenza (LPAI) viruses can silently circulate in poultry and wild aquatic birds and potentially mutate into highly pathogenic avian influenza (HPAI) viruses. In the U.S. Read More

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http://dx.doi.org/10.3390/v11020163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410290PMC
February 2019
4 Reads

Wild birds do not harbor higher diversity of influenza virus internal genes than poultry.

Virology 2019 Apr 7;530:59-64. Epub 2019 Feb 7.

Jiangsu Key Laboratory for Microbes and Functional Genomics, College of Life Sciences, Nanjing Normal University, Nanjing, Jiangsu 210023, China. Electronic address:

Avian influenza A virus (AIV) has threatened global economy and public health. Wild birds have long been thought to serve as the natural reservoir of influenza virus, and thus it is expected that wild birds harbor higher viral diversity than poultry. Yet, this hypothesis has not been formally tested. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00426822193004
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http://dx.doi.org/10.1016/j.virol.2019.02.003DOI Listing
April 2019
6 Reads

Difference in pathogenicity of 2 strains of avian leukosis virus subgroup J in broiler chicken.

Poult Sci 2019 Feb 15. Epub 2019 Feb 15.

Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong Agricultural University, 61 Daizong Street, Taian City, Shandong Province 271018, China.

Avian leukosis virus subgroup J has been found to infect many types of chickens with various genetic backgrounds. The ALV-J strain NX0101, which was isolated from broiler breeders in 2001, mainly induces the formation of myeloid cell tumors. However, strain HN10PY01, which was recently isolated from laying hens, mainly induces the formation of myeloid cell tumors and hemangioma. Read More

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http://dx.doi.org/10.3382/ps/pez065DOI Listing
February 2019
2 Reads

Emerging Influenza D Virus Threat: What We Know so Far!

J Clin Med 2019 Feb 5;8(2). Epub 2019 Feb 5.

Department of Microbiology and Immunology, Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, IL 60064, USA.

Influenza viruses, since time immemorial, have been the major respiratory pathogen known to infect a wide variety of animals, birds and reptiles with established lineages. They belong to the family and cause acute respiratory illness often during local outbreaks or seasonal epidemics and occasionally during pandemics. Recent studies have identified a new genus within the family. Read More

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http://dx.doi.org/10.3390/jcm8020192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406440PMC
February 2019
4 Reads

An avian influenza virus A(H7N9) reassortant that recently emerged in the United States with low pathogenic phenotype does not efficiently infect swine.

Influenza Other Respir Viruses 2019 May 13;13(3):288-291. Epub 2019 Feb 13.

Virus and Prion Research Unit, Agricultural Research Service, National Animal Disease Center, U.S. Department of Agriculture, Ames, Iowa.

In 2017, outbreaks of low and highly pathogenic avian H7N9 viruses were reported in four States in the United States. In total, over 270 000 birds died or were culled, causing significant economic loss. The potential for avian-to-swine transmission of the U. Read More

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http://dx.doi.org/10.1111/irv.12631DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468088PMC
May 2019
1 Read

Characterization of Mouse Monoclonal Antibodies Against the HA of A(H7N9) Influenza Virus.

Viruses 2019 Feb 11;11(2). Epub 2019 Feb 11.

Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Minato-ku, Tokyo 108-8639, Japan.

Many cases of human infection with the H7N9 virus have been detected in China since 2013. H7N9 viruses are maintained in chickens and are transmitted to humans at live bird markets. During circulation in birds, H7N9 viruses have accumulated amino acid substitutions in their hemagglutinin (HA), which resulted in an antigenically change in the recent H7N9 viruses. Read More

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http://dx.doi.org/10.3390/v11020149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410113PMC
February 2019
2 Reads

One health insights to prevent the next HxNy viral outbreak: learning from the epidemiology of H7N9.

BMC Infect Dis 2019 Feb 11;19(1):138. Epub 2019 Feb 11.

School of Public Health, Sun Yat-sen University, Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China.

Background: With an increased incidence of viral zoonoses, there is an impetus to strengthen collaborations between public health, agricultural and environmental departments. This interdisciplinary cooperation, also known as the 'One Health' approach, has received significant support from various stakeholders. However, current efforts and policies still fall short of those needed for an effective One Health approach towards disease control and prevention. Read More

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http://dx.doi.org/10.1186/s12879-019-3752-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371560PMC
February 2019
3 Reads

[Genetic characteristic of hemagglutinin of avian influenza A (H7N9) virus in Guizhou Province in 2017].

Zhonghua Yu Fang Yi Xue Za Zhi 2019 Feb;53(2):229-232

Clinical Laboratory of Institute for Communicable Disease Control and Prevention, Guizhou Center for Disease Control and Prevention, Guiyang 550004, China.

The number of H7N9 bird flu cases was high and the situation was grim in guizhou province in 2017. To understand the molecular characteristics of the hemagglutinin gene (HA) and the risk of human infection with avian influenza virus A(H7N9) in Guizhou Province, 2017. Homology, genetic evolution and pivotal sites related to receptor binding regions, pathogenicity and potential glycosylation of 14 avian influenza viruses A(H7N9) were analyzed by a series of bioinformation softwares. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0253-9624.2019.02.020DOI Listing
February 2019
1 Read