186,224 results match your criteria Autonomic Neuroscience-basic & Clinical[Journal]


[Visualisation and Radiofrequency Ablation of Sympathetic Innervation Loci in the Left Atrium in Patients with Paroxysmal Atrial Fibrillation].

Kardiologiia 2019 Apr 16;59(4):33-38. Epub 2019 Apr 16.

National Medical Research Center named after acad. E. N. Meshalkin, Novosibirsk.

Introduction: A novel cardiac gamma camera utilizes the radiopharmaceutical Iodine-123-Meta-iodobenzylguanidine (123I-MIBG) to visualize cardiac sympathetic innervation. Physiological accumulation of 123I-mIBG provides an anatomical quantitative determination of the structures of the autonomic nervous system (ANS) with discrete uptake areas (DUA) of sympathetic activity located in the left atrium (LA) corresponding to the main ganglionic plexi (GP) clusters that could not previously be visualized.

Aim: to visualize the DUA of the heart in patients with paroxysmal atrial fibrillation (AF) and to assess the effect of radiofrequency ablation (RFA) on DUA in LA. Read More

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http://dx.doi.org/10.18087/cardio.2019.4.10249DOI Listing

Distraction and reappraisal efficiency on immediate negative emotional responses: role of trait anxiety.

Anxiety Stress Coping 2019 Apr 19:1-16. Epub 2019 Apr 19.

a Institute of Psychology , University of Lausanne , Lausanne , Switzerland.

Background And Objectives: Emotion regulation involves attempts to influence emotion unfolding and may target experiential, expressive and physiological responses. Several strategies can be used, such as reappraisal (re-evaluating the emotional situation to reduce its emotional meaning) or distraction (turning the attention toward non-emotional aspects of the situation). Previous research on these regulation strategies produced contrasting results regarding their efficiency and we hypothesize that this could be due to individual differences such as trait anxiety. Read More

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http://dx.doi.org/10.1080/10615806.2019.1597859DOI Listing

Characterization of the Asymmetry of the Cardiac and Sympathetic Arms of the Baroreflex From Spontaneous Variability During Incremental Head-Up Tilt.

Front Physiol 2019 2;10:342. Epub 2019 Apr 2.

Department of Cardiothoracic, Vascular Anesthesia and Intensive Care, IRCCS Policlinico San Donato, Milan, Italy.

Hysteresis of the baroreflex (BR) is the result of the different BR sensitivity (BRS) when arterial pressure (AP) rises or falls. This phenomenon has been poorly studied and almost exclusively examined by applying pharmacological challenges and static approaches disregarding causal relations. This study inspects the asymmetry of the cardiac BR (cBR) and vascular sympathetic BR (sBR) in physiological closed loop conditions from spontaneous fluctuations of physiological variables, namely heart period (HP) and systolic AP (SAP) leading to the estimation of cardiac BRS (cBRS) and muscle sympathetic nerve activity (MSNA) and diastolic AP (DAP) leading to the estimation of vascular sympathetic BRS (sBRS). Read More

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http://dx.doi.org/10.3389/fphys.2019.00342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454064PMC

Proconvertase Furin Is Downregulated in Postural Orthostatic Tachycardia Syndrome.

Front Neurosci 2019 29;13:301. Epub 2019 Mar 29.

Department of Clinical Sciences, Faculty of Medicine, Clinical Research Center, Lund University, Malmö, Sweden.

Postural Orthostatic Tachycardia Syndrome (POTS) is a cardiovascular autonomic disorder characterized by orthostatic intolerance and high prevalence among young women. The etiology of POTS is uncertain, though autoimmunity and inflammation may play an important role. We aimed to identify novel inflammatory biomarkers associated with POTS. Read More

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https://www.frontiersin.org/article/10.3389/fnins.2019.00301
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http://dx.doi.org/10.3389/fnins.2019.00301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455076PMC
March 2019
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Changes in MIDAS, Perceived Stress, Frontalis Muscle Activity and Non-Steroidal Anti-Inflammatory Drugs Usage in Patients with Migraine Headache without Aura following Ayurveda and Yoga Compared to Controls: An Open Labeled Non-Randomized Study.

Ann Neurosci 2018 Dec 11;25(4):250-260. Epub 2018 Sep 11.

Division of Yoga and Life Sciences, Swami Vivekananda Yoga Anusandhana Samsthana (S-VYASA) A Deemed to be University, Bengaluru, India.

Background: There has been a significant increase in the use of complementary and integrative medicine to provide long-term healing solutions in migraine headache patients. Knowing the limitations of conventional medical approach, the present study evaluated the influence of two Indian traditional systems of medicine on migraine-related disability, autonomic variables, perceived stress, and muscle activity in patients with migraine headache without aura.

Methods: Thirty subjects recruited to the Ayurveda and Yoga (AY) group underwent traditional (Bio-purification) using therapeutic Purgation followed by yoga therapy, while 30 subjects of control (CT) group continued on symptomatic treatment (non-steroidal anti-inflammatory drugs [NSAID's]) for 90 days. Read More

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http://dx.doi.org/10.1159/000492269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470355PMC
December 2018

The expression of androgen receptor in neurons of the anterior pelvic ganglion and celiac-superior mesenteric ganglion in the male pig.

Pol J Vet Sci 2019 Mar;22(1):151-155

Department of Animal Anatomy, Faculty of Veterinary Medicine, University of Warmia and Mazury, Oczapowskiego 13, 10-718 Olsztyn, Poland.

The present study investigated the expression of androgen receptor (AR) in neurons of the anterior pelvic ganglion (APG) and celiac-superior mesenteric ganglion (CSMG; ganglion not involved in the innervation of reproductive organs) in the male pig with quantitative real-time PCR (qPCR) and immunohistochemistry. qPCR investigations revealed that the level of AR gene expression in the APG tissue was approximately 2.5 times higher in the adult (180-day-old) than in the juvenile (7-day-old) boars. Read More

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http://dx.doi.org/10.24425/pjvs.2019.127081DOI Listing

Tonic pupils: an unusual autonomic involvement in chronic inflammatory demyelinating polyneuropathy (CIDP).

Neurol Sci 2019 Apr 17. Epub 2019 Apr 17.

Department of Neurology, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Pedro de Toledo, 650, São Paulo, SP, 04039-002, Brazil.

Background: Chronic inflammatory demyelinating polyneuropathy (CIDP) is a neuropathy which affects mainly large myelinated axons and has a typically mild autonomic dysfunction mainly from postganglionic nerve fiber involvement.

Case Report: We report here an acute onset CIDP initially diagnosed as Guillain-Barré syndrome (GBS), unresponsive to treatment with intravenous immunoglobulin (IVIg), which later responded to plasmapheresis and corticoids. The patient had a markedly distal demyelination, prominent cranial nerve involvement and, interestingly, bilateral fixed dilated pupils. Read More

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http://dx.doi.org/10.1007/s10072-019-03890-8DOI Listing
April 2019
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Exploring hyperhidrosis and related thermoregulatory symptoms as a possible clinical identifier for the dysautonomic subtype of Parkinson's disease.

J Neurol 2019 Apr 17. Epub 2019 Apr 17.

King's College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Basic and Clinical Neurosciences, De Crespigny Park, London, SE5 8AF, UK.

Objective: To identify associated (non-)motor profiles of Parkinson's disease (PD) patients with hyperhidrosis as a dominant problem.

Methods: This is a cross-sectional, exploratory, analysis of participants enrolled in the Non-motor Longitudinal International Study (NILS; UKCRN No: 10084) at the Parkinson's Centre at King's College Hospital (London, UK). Hyperhidrosis scores (yes/no) on question 28 of the Non-Motor Symptom Questionnaire were used to classify patients with normal sweat function (n = 172) and excessive sweating (n = 56) (Analysis 1; n = 228). Read More

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http://dx.doi.org/10.1007/s00415-019-09325-wDOI Listing

Pacing therapy in the management of unexplained syncope: a tertiary care centre prospective study.

Open Heart 2019 25;6(1):e001015. Epub 2019 Mar 25.

Department of Clinical Sciences, Lund University, Malmö, Sweden.

Objective: Pacemaker (PM) therapy is effective when syncope is associated with bradycardia, but syncope recurrences and fall injuries after PM implantation may occur. We aimed to survey indications and outcomes of PM implantation, following evaluation of unexplained syncope.

Methods: Among 1666 consecutive unpaced patients investigated in a tertiary syncope unit by carotid-sinus massage (CSM), head-up tilt test (HUT) and ECG monitoring, 106 (6. Read More

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http://openheart.bmj.com/lookup/doi/10.1136/openhrt-2019-001
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http://dx.doi.org/10.1136/openhrt-2019-001015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443123PMC
March 2019
2 Reads

Scorpion venom increases acetylcholine release by prolonging the duration of somatic nerve action potentials.

Neuropharmacology 2019 Apr 14. Epub 2019 Apr 14.

Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Robertson Trust Wing Building, Room 601, 161 Cathedral Street, G4 0RE, Glasgow, UK. Electronic address:

Scorpionism is frequently accompanied by a massive release of catecholamines and acetylcholine from peripheral nerves caused by neurotoxic peptides present in these venoms, which have high specificity and affinity for ion channels. Tityus bahiensis (T. bahiensis) is the second most medically important scorpion species in Brazil but, despite this, its venom remains scarcely studied, especially with regard to its pharmacology on peripheral (somatic and autonomic) nervous system. Read More

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http://dx.doi.org/10.1016/j.neuropharm.2019.04.013DOI Listing
April 2019
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Enhancement of excitatory transmission in NTS neurons projecting to ventral medulla of rats exposed to sustained hypoxia is blunted by minocycline.

J Physiol 2019 Apr 17. Epub 2019 Apr 17.

Department of Physiology, School of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, 14049-900, SP, Brazil.

Key Points: -Rats submitted to sustained hypoxia (SH) presents increase in arterial pressure (AP) as well as increase in glutamatergic transmission in the nucleus tractus solitarius (NTS) neurons sending projections to ventrolateral medulla (VLM). -Treatment with minocycline, a microglial inhibitor, attenuated the increase in AP in response to SH. -The increase in the amplitude of glutamatergic post-synaptic currents in the NTS-VLM neurons, induced by post-synaptic mechanisms, was blunted by minocycline treatment. Read More

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http://dx.doi.org/10.1113/JP277532DOI Listing

Authors' response to the letter: Takotsubo syndrome: a neurocardiac syndrome inside the autonomic nervous system.

Heart Fail Rev 2019 Apr 16. Epub 2019 Apr 16.

Department of Experimental and Clinical Physiology, Laboratory of Centre for Preclinical Research, Medical University of Warsaw, 1b Banacha Street, 02-097, Warsaw, Poland.

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http://dx.doi.org/10.1007/s10741-019-09789-yDOI Listing

Dysautonomia and hyponatraemia as harbingers of Guillain-Barre syndrome.

BMJ Case Rep 2019 Apr 15;12(4). Epub 2019 Apr 15.

Department of Critical Care, Jaslok Hospital and Research Centre, Mumbai, Maharashtra, India.

A 56-year-old woman with a medical history of hypertension presented to our hospital with back pain, abdominal pain, vomiting and elevated blood pressure. The laboratory parameters including evaluation for secondary hypertension were within normal ranges at the time of presentation. During her hospitalisation, fluctuations in her blood pressure and pulse were observed which were attributed to autonomic disturbances, the cause of which was unknown. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22692
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http://dx.doi.org/10.1136/bcr-2018-226925DOI Listing
April 2019
2 Reads

Increased QT and P-wave dispersion during attack-free period in pediatric patients with migraine attacks.

Cardiol Young 2019 Apr 17:1-4. Epub 2019 Apr 17.

Department of Pediatric Neurology,Medeniyet University Faculty of Medicine,Istanbul,Turkey.

Introduction: Migraine is a common neurovascular disease characterised with recurrent attacks by pain-free periods. It has been suggested that both sympathetic and parasympathetic dysfunctions play a role in its pathophysiology.

Aim: The aim of our study was to investigate the ECG changes during attack-free period in children with migraine, in terms of QTc interval, QTc, and P-wave dispersion to evaluate the autonomic nervous system disturbance. Read More

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http://dx.doi.org/10.1017/S1047951119000088DOI Listing

Clinical characteristics of autoimmune GFAP astrocytopathy.

J Neuroimmunol 2019 Apr 9;332:91-98. Epub 2019 Apr 9.

Department of Neurology and Geriatrics, Gifu University Graduate School of Medicine, Gifu, Japan.

The clinical features of autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy remain to be elucidated. We describe here the clinical features of 14 patients with GFAP astrocytopathy confirmed by detection of GFAP-IgG in cerebrospinal fluid (CSF). The novel findings of this study are as follows. Read More

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http://dx.doi.org/10.1016/j.jneuroim.2019.04.004DOI Listing
April 2019
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The impact of informal cancer caregiving: A literature review on psychophysiological studies.

Eur J Cancer Care (Engl) 2019 Apr 16:e13042. Epub 2019 Apr 16.

Departamento de Psicologia, Centro de Investigação em Psicologia (CIP-UAL), Universidade Autónoma de Lisboa Luís de Camões, Lisboa, Portugal.

Caregiving can be experienced as a stressful process, which can cause psychological and physical consequences. The combination of prolonged stress and the physical demands of caregiving may impair the physiological functioning of caregivers and increase the risk of health problems creating considerable stress in the life of caregivers regarding emotional, physical, social and financial areas. This literature review explored studies that used measures of the autonomic nervous system in caregivers of oncology patients such as electrodermal and cardiovascular (re)activity. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/ecc.13042
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http://dx.doi.org/10.1111/ecc.13042DOI Listing
April 2019
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Role of autonomic dysfunction in the regulation of myocardial blood flow in systemic sclerosis evaluated by cardiac magnetic resonance.

Int J Rheum Dis 2019 Apr 15. Epub 2019 Apr 15.

Department of Clinical Medicine, Clinical Immunology Unit-Scleroderma Center, Sapienza University of Rome, Rome, Italy.

Aim: Autonomic dysfunction (AD) is an early feature of systemic sclerosis (SSc). A regular endothelial function is a prerequisite for normal response of the myocardial blood flow (MBF) to cold pressure test (CPT). The aim of the study was to evaluate the relation between MBF and AD at rest and after CPT in asymptomatic SSc patients. Read More

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http://dx.doi.org/10.1111/1756-185X.13569DOI Listing
April 2019
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Selective Sensory Axon Reinnervation and TRPV1 Activation.

Mol Neurobiol 2019 Apr 15. Epub 2019 Apr 15.

Division of Neurology, Department of Medicine and the Neuroscience and Mental Health Institute, University of Alberta, 132A-Clinical Sciences Building, 11350 Ave, Edmonton, Alberta, T6G 2G3, Canada.

Current strategies to enhance regeneration of peripheral neurons involve broad activation of sensory, autonomic, and motor axons. Peripheral neuron regeneration is limited in persons with damage or disease of peripheral axons. Here, we provide evidence that subtoxic activation of TRPV1 channels in sensory neurons is associated with activation of growth and subtle changes in skin reinnervation. Read More

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http://link.springer.com/10.1007/s12035-019-1574-6
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http://dx.doi.org/10.1007/s12035-019-1574-6DOI Listing
April 2019
4 Reads

Time-Resolved Directional Brain-Heart Interplay Measurement Through Synthetic Data Generation Models.

Ann Biomed Eng 2019 Apr 15. Epub 2019 Apr 15.

Bioengineering and Robotics Research Center E.Piaggio & Department of Information Engineering, School of Engineering, University of Pisa, Largo Lucio Lazzarino 1, 56122, Pisa, Italy.

Although a plethora of synthetic data generation models have been proposed to validate biomarkers of brain and cardiovascular dynamics separately, a limited number of computational methods estimating directed brain-heart information flow are currently available in the scientific literature. This study introduces a computational framework exploiting existing generative models for a novel time-resolved quantification of causal brain-heart interplay. Exemplarily, having electroencephalographic signals and heart rate variability series as inputs, respective synthetic data models are coupled through parametrised functions defined in accordance with current central autonomic network (CAN) knowledge. Read More

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http://dx.doi.org/10.1007/s10439-019-02251-yDOI Listing

Haemodynamic changes during prone positioning in anaesthetised chronic cervical myelopathy patients.

Indian J Anaesth 2019 Mar;63(3):212-217

Department of Neuroanesthesia and Neurocritical Care, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.

Background And Aims: Anaesthetised patients, when positioned prone, experience hypotension and reduction in cardiac output. Associated autonomic dysfunction in cervical myelopathy patients predisposes them to haemodynamic changes. The combined effect of prone positioning and autonomic dysfunction in anaesthetised patients remains unknown. Read More

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http://dx.doi.org/10.4103/ija.IJA_810_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423938PMC

Low plasma adropin concentrations increase risks of weight gain and metabolic dysregulation in response to a high-sugar diet in male nonhuman primates.

J Biol Chem 2019 Apr 15. Epub 2019 Apr 15.

University of California Davis.

Mouse studies linking adropin, a peptide hormone encoded by the energy homeostasis associated () gene, to biological clocks and to glucose and lipid metabolism suggest a potential therapeutic target for managing diseases of metabolism. However, adropin's roles in human metabolism are unclear. expression profiling in a nonhuman primate diurnal transcriptome atlas (GSE98965) revealed a dynamic and diurnal pattern of expression. Read More

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http://dx.doi.org/10.1074/jbc.RA119.007528DOI Listing

Measles, magic and misidentifications: a defence of the two-factor theory of delusions.

Authors:
Ryan McKay

Cogn Neuropsychiatry 2019 Apr 16:1-8. Epub 2019 Apr 16.

a Department of Psychology , Royal Holloway, University of London , Egham , UK.

Corlett (Corlett, P. (this issue). Factor one, familiarity and frontal cortex: A challenge to the two-factor theory of delusions. Read More

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http://dx.doi.org/10.1080/13546805.2019.1607273DOI Listing

Hyperglycaemia-Induced Downregulation in Expression of nNOS Intramural Neurons of the Small Intestine in the Pig.

Int J Mol Sci 2019 Apr 4;20(7). Epub 2019 Apr 4.

Department of Clinical Physiology Faculty of Veterinary Medicine, University of Warmia and Mazury, Oczapowskiego Str. 13, 10-719 Olsztyn, Poland.

Diabetic autonomic peripheral neuropathy (PN) involves a broad spectrum of organs. One of them is the gastrointestinal (GI) tract. The molecular mechanisms underlying the pathogenesis of digestive complications are not yet fully understood. Read More

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http://dx.doi.org/10.3390/ijms20071681DOI Listing
April 2019
2 Reads

High Cervical Spinal Cord Stimulation: A One Year Follow-Up Study on Motor and Non-Motor Functions in Parkinson's Disease.

Brain Sci 2019 Apr 3;9(4). Epub 2019 Apr 3.

Department of Biotechnological and Applied Clinical Sciences (DISCAB), University of L'Aquila, 67100 L'Aquila, Italy.

Background: The present study investigated the effectiveness of stimulation applied at cervical levels on pain and Parkinson's disease (PD) symptoms using either tonic or burst stimulation mode.

Methods: Tonic high cervical spinal cord stimulation (T-HCSCS) was applied on six PD patients suffering from low back pain and failed back surgery syndrome, while burst HCSCS (B-HCSCS) was applied in twelve PD patients to treat primarily motor deficits. Stimulation was applied percutaneously with quadripolar or octapolar electrodes. Read More

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http://dx.doi.org/10.3390/brainsci9040078DOI Listing

Autonomic Nervous System Team-Based Learning Module.

MedEdPORTAL 2016 Nov 29;12:10507. Epub 2016 Nov 29.

Assistant Professor of Neuroscience, Department of Biomedical Sciences, Oakland University William Beaumont School of Medicine.

Introduction: The team-based learning (TBL) instructional strategy promotes learning and retention, enhances student engagement, allows for a deeper understanding of foundational and applied concepts, and helps students' develop lifelong learning skills. The autonomic nervous system (ANS) TBL was created for first-year medical students in the Neuroscience 1 course at Oakland University William Beaumont School of Medicine.

Methods: The module covered the pathophysiology of ANS-related diseases and therapeutic agents that impact ANS function. Read More

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http://dx.doi.org/10.15766/mep_2374-8265.10507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440417PMC
November 2016

Influence of Sex, Menstrual Cycle, and Menopause Status on the Exercise Pressor Reflex.

Med Sci Sports Exerc 2019 May;51(5):874-881

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.

In this review, we highlight the underlying mechanisms responsible for the sex differences in the exercise pressor reflex (EPR), and, importantly, the impact of sex hormones and menopausal status. The EPR is attenuated in premenopausal women compared with age-matched men. Specifically, activation of the metaboreflex (a component of the EPR) results in attenuated increases in blood pressure and sympathetic vasomotor outflow compared with age-matched men. Read More

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http://dx.doi.org/10.1249/MSS.0000000000001877DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467496PMC

Cervical ganglioneuroma: A case report and review of the literature.

Medicine (Baltimore) 2019 Apr;98(15):e15203

Department of Otolaryngology-Head and Neck Surgery, First Hospital of Jilin University, Jilin University, Changchun 130021, Jilin Province, China.

Rationale: Ganglioneuromas are benign neoplasm of neuroblastic origin which arise from central or peripheral parts of the autonomic nervous system. They are normally found at posterior mediastinum, retroperitoneum, and the adrenal gland but ganglioneuromas are rarely found in the cervical region.

Patient Concerns: A 12-year-old boy was admitted with a left-lateral neck mass slow growing over a 7-days duration. Read More

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http://dx.doi.org/10.1097/MD.0000000000015203DOI Listing
April 2019
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Health and Disease-Emergent States Resulting From Adaptive Social and Biological Network Interactions.

Front Med (Lausanne) 2019 28;6:59. Epub 2019 Mar 28.

Department Geriatric Medicine, Radboud University Medical Center, Nijmegen, Netherlands.

Health is an adaptive state unique to each person. This subjective state must be distinguished from the objective state of disease. The experience of health and illness (or poor health) can occur both in the absence and presence of objective disease. Read More

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http://dx.doi.org/10.3389/fmed.2019.00059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447670PMC

Cardiorespiratory Coupling Analysis Based on Entropy and Cross-Entropy in Distinguishing Different Depression Stages.

Front Physiol 2019 29;10:359. Epub 2019 Mar 29.

School of Instrument Science and Engineering, Southeast University, Nanjing, China.

Aims: This study used entropy- and cross entropy-based methods to explore the cardiorespiratory coupling of depressive patients, and thus to assess the values of those entropy methods for identifying depression patients with different disease severities.

Methods: Electrocardiogram (ECG) and respiration signals from 69 depression patients were recorded simultaneously for 5 min. Patients were classified into three groups according to the Hamilton Depression Rating Scale (HDRS) scores: group Non-De (HDRS 0-7), Mid-De (HDRS 8-17), and Con-De (HDRS >17). Read More

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http://dx.doi.org/10.3389/fphys.2019.00359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449862PMC
March 2019
1 Read

Exercise-Induced Changes of Multimodal Interactions Within the Autonomic Nervous Network.

Front Physiol 2019 29;10:240. Epub 2019 Mar 29.

Institute of Sports Medicine, University of Paderborn, Paderborn, Germany.

Physical exercise has been shown to modulate activity within the autonomic nervous system (ANS). Considering physical exercise as a holistic stimulus on the nervous system and specifically the ANS, uni- and multimodal analysis tools were applied to characterize centrally driven interactions and control of ANS functions. Nineteen young and physically active participants performed treadmill tests at individually determined moderate and high intensities. Read More

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http://dx.doi.org/10.3389/fphys.2019.00240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449462PMC
March 2019
2 Reads

Prokinetic effects of spinal cord stimulation and its autonomic mechanisms in dogs.

Neurogastroenterol Motil 2019 Apr 14:e13596. Epub 2019 Apr 14.

Division of Gastroenterology and Hepatology, Johns Hopkins Center for Neurogastroenterology, Baltimore, Maryland.

Background: Spinal cord stimulation (SCS) is widely used to treat chronic pain by inhibiting sympathetic activity; however, it is unknown whether it exerts a prokinetic effect on gastric motility. Our aim was to explore effects and possible mechanisms of SCS on glucagon-induced gastric dysmotility and dysrhythmia.

Methods: Seven female dogs with electrodes chronically placed on the dorsal column of the spinal cord between T10 and T12 segments were studied in 2 randomized sessions (glucagon + sham-SCS, glucagon + SCS). Read More

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http://dx.doi.org/10.1111/nmo.13596DOI Listing

Clinical Predictors of Rapid Gastric Emptying in Patients Presenting with Dyspeptic Symptoms.

Dig Dis Sci 2019 Apr 13. Epub 2019 Apr 13.

Digestive Diseases and Surgery Institute, Cleveland Clinic, Cleveland, OH, USA.

Background: Rapid gastric emptying (RGE) is defined as less than 30% retention at 1 h of solid meal ingestion. It is unclear whether RGE represents a separated clinical entity or part of the functional dyspepsia spectrum.

Aims: To determine clinical predictors of RGE in patients presenting with dyspeptic symptoms. Read More

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http://dx.doi.org/10.1007/s10620-019-05620-8DOI Listing

Prognostic Significance of Heart Rate Turbulence Parameters in Patients with Noncompaction Cardiomyopathy.

Cardiology 2019 Apr 12;142(1):56-62. Epub 2019 Apr 12.

University of Kyrenia, Department of Cardiology, Kyrenia, Cyprus,

Background: Noncompaction cardiomyopathy (NC) is a rare congenital heart disease characterized by progressive heart failure and life-threatening arrhythmias. Heart rate turbulence (HRT) has been defined as a noninvasive prognostic method to reveal the cardiac death risk in high-risk patients.

Objectives: We aimed to assess the cardiac autonomic functions and their relations to the mortality in NC patients. Read More

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http://dx.doi.org/10.1159/000499408DOI Listing

The relationship between heart rate and functional connectivity of brain regions involved in autonomic control.

Neuroimage 2019 Apr 11. Epub 2019 Apr 11.

Psychiatric Brain and Body Research Group, Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena, Germany. Electronic address:

The peripheral autonomic nervous system (ANS) adjusts the heart rate (HR) to intrinsic and extrinsic demands. It is controlled by a group of functionally connected brain regions assembling the so-called central autonomic network (CAN). More specifically, forebrain cortical regions, limbic and brainstem structures within the CAN have been identified as important components of circuits involved in HR regulation. Read More

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http://dx.doi.org/10.1016/j.neuroimage.2019.04.014DOI Listing

The Potential Implication of the Autonomic Nervous System in Hepatocellular Carcinoma.

Cell Mol Gastroenterol Hepatol 2019 Apr 11. Epub 2019 Apr 11.

UMR5286, CNRS, INSERM U1052, Cancer Research Centre of Lyon, Lyon, France; University of Lyon, Lyon, France; DevWeCan Laboratories of Excellence Network (Labex), Lyon, France; Hepatogastroenterology Service, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France.

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http://dx.doi.org/10.1016/j.jcmgh.2019.03.002DOI Listing

Gentle perineal skin stimulation for control of nocturia.

Anat Rec (Hoboken) 2019 Apr 12. Epub 2019 Apr 12.

Department of Autonomic Neuroscience, Tokyo Metropolitan Institute of Gerontology, Tokyo 173-0015, Japan.

One of the major causes of nocturia is overactive bladder (OAB). Somatic afferent nerve stimuli are used for treating OAB. However, clinical evidence for the efficacy of this treatment is insufficient due to the lack of appropriate control stimuli. Read More

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http://dx.doi.org/10.1002/ar.24135DOI Listing

[Diabetic neuropathy and diabetic foot syndrome (Update 2019)].

Wien Klin Wochenschr 2019 Apr 12. Epub 2019 Apr 12.

Universitätsklinik für Innere Medizin, Medizinische Universität Graz, Graz, Österreich.

These are the guidelines for diagnosis and treatment of diabetic neuropathy and diabetic foot. Diabetic neuropathy comprises a number of mono- and polyneuropathies, plexopathies, radiculopathies and autonomic neuropathy.The position statement summarizes characteristic clinical symptoms and techniques for diagnostic assessment of diabetic neuropathy, including the complex situation of the diabetic foot syndrome. Read More

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http://link.springer.com/10.1007/s00508-019-1487-4
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http://dx.doi.org/10.1007/s00508-019-1487-4DOI Listing
April 2019
2 Reads

Cardiac and Peripheral Autonomic Responses to Orthostatic Stress During Transcutaneous Vagus Nerve Stimulation in Healthy Subjects.

J Clin Med 2019 Apr 11;8(4). Epub 2019 Apr 11.

Department of Internal Medicine, Fondazione IRCSS Ca' Granda, Ospedale Maggiore Policlinico, 20122 Milan, Italy.

Previous studies showed that transcutaneous vagus nerve stimulation (tVNS) modulates the autonomic nervous system (ANS) in resting condition. However, the autonomic regulation in response to an orthostatic challenge during tVNS in healthy subjects remains unknown. We tested the hypothesis that tVNS reduces heart rate (HR) and alters the responsivity of ANS to orthostatic stress in healthy subjects. Read More

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http://dx.doi.org/10.3390/jcm8040496DOI Listing
April 2019
1 Read

Noise Exposure Accelerates the Risk of Cognitive Impairment and Alzheimer's Disease: Adulthood, Gestational, and Prenatal Mechanistic Evidence from Animal Studies.

Neurosci Biobehav Rev 2019 Apr 9. Epub 2019 Apr 9.

Department of Neuroscience, Canadian Centre for Behavioural Neuroscience, University of Lethbridge, Lethbridge, AB, T1K 3M4, Canada. Electronic address:

This review examines the adverse impacts of different noise exposure paradigms on the neuroendocrine system, hippocampal and neocortical structures, cognitive performances, and the development of Alzheimer's disease (AD)-like neuropathological changes in the brain of laboratory animals. Studies were reviewed in three periods during the lifespan including: adult animals exposed to noise, female rodents exposed to noise during gestation, and offspring exposed to noise during the prenatal period. Findings imply that chronic noise exposure dysregulates the neuroendocrine system leading to hyperactivation of the sympathetic divisions of the autonomic nervous system (i. Read More

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http://dx.doi.org/10.1016/j.neubiorev.2019.04.001DOI Listing
April 2019
1 Read

Region-Specific Effects of Trigeminal Capsaicin Stimulation.

J Oral Facial Pain Headache 2019 Apr 12. Epub 2019 Apr 12.

Aims: To investigate the region-specific effects of painful trigeminal capsaicin stimulation in healthy participants.

Methods: Twenty healthy participants (10 men and 10 women) participated in four sessions in which they received application of 0.05 mL Vaseline (placebo) or capsaicin cream (0. Read More

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http://dx.doi.org/10.11607/ofph.2303DOI Listing

Effects of interval training on risk markers for arrhythmic death: a randomized controlled trial.

Clin Rehabil 2019 Apr 12:269215519840388. Epub 2019 Apr 12.

1 Cardiovascular Prevention and Rehabilitation (EPIC) Center, Montreal Heart Institute and University of Montreal, Montreal, QC, Canada.

Objective: To compare the effects of high-intensity interval training versus moderate-intensity continuous training on risk markers of arrhythmic death in patients who recently suffered from an acute coronary syndrome.

Design: Double-blind (patient and evaluator) randomized controlled trial.

Setting: Cardiovascular Prevention and Rehabilitation Centre (EPIC Centre) of the Montreal Heart Institute, Montreal, Canada. Read More

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http://dx.doi.org/10.1177/0269215519840388DOI Listing
April 2019
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Dietary heat-killed Lactobacillus brevis SBC8803 (SBL88™) improves hippocampus-dependent memory performance and adult hippocampal neurogenesis.

Neuropsychopharmacol Rep 2019 Apr 11. Epub 2019 Apr 11.

Department of Bioscience, Faculty of Applied Bioscience, Tokyo University of Agriculture, Setagaya-ku, Tokyo, Japan.

Aims: Lactobacillus species are used widely as various food and supplements to improve health. Previous studies have shown that heat-killed Lactobacillus brevis SBC8803 induces serotonin release from intestinal cells and affects sleep rhythm and the autonomic nervous system. However, the effect of SBC8803 on cognitive function remains unknown. Read More

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http://dx.doi.org/10.1002/npr2.12054DOI Listing

A temporal and spatial map of axons in developing mouse prostate.

Histochem Cell Biol 2019 Apr 11. Epub 2019 Apr 11.

Molecular and Environmental Toxicology Center, University of Wisconsin-Madison, Madison, WI, USA.

Prostate autonomic and sensory axons control glandular growth, fluid secretion, and smooth muscle contraction and are remodeled during cancer and inflammation. Morphogenetic signaling pathways reawakened during disease progression may drive this axon remodeling. These pathways are linked to proliferative activities in prostate cancer and benign prostate hyperplasia. Read More

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http://link.springer.com/10.1007/s00418-019-01784-6
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http://dx.doi.org/10.1007/s00418-019-01784-6DOI Listing
April 2019
3 Reads

Mental stress causes vasoconstriction in sickle cell disease and normal controls.

Haematologica 2019 Apr 11. Epub 2019 Apr 11.

Children's Hospital Los Angeles;

Vaso-occlusive crisis is a hallmark of sickle cell disease where deoxygenated sickled red blood cells occlude the microvasculature. Any stimulus like mental stress that decreases microvascular blood flow will increase likelihood of red cell entrapment resulting in local vaso-occlusion and progression to vaso-occlusive crisis. Neurally mediated vasoconstriction might be the physiologic link between crisis triggers and vaso-occlusion. Read More

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http://www.haematologica.org/lookup/doi/10.3324/haematol.201
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http://dx.doi.org/10.3324/haematol.2018.211391DOI Listing
April 2019
2 Reads

Multiple system atrophy mimicked by multi-organ pathology.

Pract Neurol 2019 Apr 11. Epub 2019 Apr 11.

Department of Neurology, Leeds Teaching Hospitals NHS Trust, Leeds, UK

Both multiple system atrophy and Parkinson's disease may present with parkinsonism and autonomic dysfunction. We describe a patient who initially met the diagnostic criteria for multiple system atrophy and had atypical features for Parkinson's disease including blackouts and pyramidal signs. Ultimately, he was found to have three separate diagnoses rather than a single unifying one. Read More

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http://pn.bmj.com/lookup/doi/10.1136/practneurol-2019-002233
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http://dx.doi.org/10.1136/practneurol-2019-002233DOI Listing
April 2019
2 Reads

Heart rate variability monitoring for emotion and disorders of emotion.

Physiol Meas 2019 Apr 11. Epub 2019 Apr 11.

School of Instrument Science and Engineering, Southeast University, Sipailou 2, Nanjing, Jiangsu, 210096, CHINA.

Emotion is composed of cognitive processing, physiological response and behavioral reaction. Heart rate variability (HRV) refers to the fluctuations between consecutive heartbeat cycles, which is considered as non-invasive method for evaluating cardiac autonomic function. HRV analysis plays an important role in emotional study and detection. Read More

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http://dx.doi.org/10.1088/1361-6579/ab1887DOI Listing

Association of thyroid function with white coat hypertension and sustained hypertension.

J Clin Hypertens (Greenwich) 2019 Apr 11. Epub 2019 Apr 11.

Department of Cardiology, Institute of Field Surgery, Daping Hospital, Army Military Medical University, Chongqing, China.

This study aimed to explore the relationship of thyroid-stimulating hormone (TSH), free triiodothyronine (FT3), and free thyroxine (FT4) levels with hypertension subtypes. 1056 euthyroid adults were included as research samples. They underwent measurement of clinic blood pressure and 24-hours ambulatory blood pressure monitoring. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jch.13536
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http://dx.doi.org/10.1111/jch.13536DOI Listing
April 2019
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Neuromuscular dentistry and the role of the autonomic nervous system: Sphenopalatine ganglion blocks and neuromodulation. An International College of Cranio Mandibular Orthopedics (ICCMO) position paper.

Authors:
Ira L Shapira

Cranio 2019 May;37(3):201-206

a Regent, Master & Fellow , International College of Cranio Mandibular Orthopedics (ICCMO), Private Practice, Delany Dental Care, Gurnee, IL and Think Better Life , Highland Park , IL , USA.

The Sphenopalatine Ganglion (SPG) is known to play an integral role in the pathophysiology of a wide variety of orofacial pains involving the jaws, sinuses, eyes and the trigeminal autonomic cephalalgias. It supplies direct parasympathetic innervation to the trigeminal and facial nerves. Sympathetic innervation from the superior sympathetic chain passes thru the SPG to the trigeminal and facial nerves. Read More

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http://dx.doi.org/10.1080/08869634.2019.1592807DOI Listing