161,454 results match your criteria Automated Software Engineering[Journal]

Building Consensus for a Shared Definition of Adverse Events: A Case Study in the Profession of Dentistry.

J Patient Saf 2022 Aug;18(5):470-474

School of Dentistry, The University of Texas Health Science Center at Houston, Houston, Texas.

Background: To achieve high-quality health care, adverse events (AEs) must be proactively recognized and mitigated. However, there is often ambiguity in applying guidelines and definitions. We describe the iterative calibration process needed to achieve a shared definition of AEs in dentistry. Read More

View Article and Full-Text PDF

Predicting Topographic Disease Progression and Treatment Response of Pegcetacoplan in Geographic Atrophy Quantified by Deep Learning.

Ophthalmol Retina 2022 Aug 7. Epub 2022 Aug 7.

Department of Ophthalmology, Medical University of Vienna, Austria. Electronic address:

Purpose: To identify disease activity and effects of intravitreal pegcetacoplan treatment on the topographic progression of geographic atrophy (GA) secondary to age-related macular degeneration (AMD) quantified in SD-OCT images by automated deep learning assessment.

Design: Retrospective analysis of a phase 2 clinical trial study evaluating pegcetacoplan in patients with GA (FILLY, NCT02503332).

Subjects: SD-OCT scans of 57 eyes with monthly, 46 eyes with every-other-month (EOM) treatment and 53 eyes with sham (SM) injection from baseline and 12 month follow up were included, in total 312 scans. Read More

View Article and Full-Text PDF

Perioperative course and socioeconomic status predict long-term neurodevelopment better than perioperative conventional neuroimaging in children with congenital heart disease.

J Pediatr 2022 Aug 7. Epub 2022 Aug 7.

Child Development Center, University Children's Hospital Zurich, Switzerland; Children's Research Center, University Children's Hospital Zurich, Switzerland; University of Zurich, Switzerland. Electronic address:

Objective: To compare the use of neonatal conventional brain magnetic resonance imaging (MRI) with that of clinical factors and socioeconomic status (SES) to predict long-term neurodevelopment in children with severe congenital heart disease (CHD).

Study Design: In this prospective cohort study, perioperative MRIs were acquired in 57 term-born infants with CHD undergoing cardiopulmonary bypass surgery during their first year of life. Total brain volume (TBV) was measured using an automated method. Read More

View Article and Full-Text PDF

Machine-learning media bias.

PLoS One 2022 10;17(8):e0271947. Epub 2022 Aug 10.

Dept. of Physics and Institute for AI & Fundamental Interactions, Massachusetts Institute of Technology, Cambridge, MA, United States of America.

We present an automated method for measuring media bias. Inferring which newspaper published a given article, based only on the frequencies with which it uses different phrases, leads to a conditional probability distribution whose analysis lets us automatically map newspapers and phrases into a bias space. By analyzing roughly a million articles from roughly a hundred newspapers for bias in dozens of news topics, our method maps newspapers into a two-dimensional bias landscape that agrees well with previous bias classifications based on human judgement. Read More

View Article and Full-Text PDF

AdipoQ - a simple, open-source software to quantify adipocyte morphology and function in tissues and .

Mol Biol Cell 2022 Aug 10:mbcE21110592. Epub 2022 Aug 10.

Institute of Innate Immunity, Biophysical Imaging, Medical Faculty, University of Bonn, 53127 Bonn, Germany.

The different adipose tissues can be distinguished according to their function. For example, white adipose tissue (WAT) stores energy in form of lipids, whereas brown adipose tissue (BAT) dissipates energy in the form of heat. These functional differences are represented in the respective adipocyte morphology: whereas white adipocytes contain large, unilocular lipid droplets, brown adipocytes contain smaller, multilocular lipid droplets. Read More

View Article and Full-Text PDF

Bioactive Natural Products Identification Using Automation of Molecular Networking Software.

J Chem Inf Model 2022 Aug 10. Epub 2022 Aug 10.

Department of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, 3306 Walker Building, Auburn, Alabama 36849, United States.

Secondary metabolites from natural sources are promising starting points for discovering and developing drug prototypes and new drugs, as many current treatments for numerous diseases are directly or indirectly related to such compounds. Recent advances in bioinformatics tools and molecular networking methods have made it possible to identify novel bioactive compounds. In this study, a workflow combining network-based methods for identifying bioactive compounds found in natural products was streamlined by innovating an automated bioinformatics software. Read More

View Article and Full-Text PDF

Comparison of the visual field test of Glaufield Lite with Humphrey Field Analyser.

Int Ophthalmol 2022 Aug 10. Epub 2022 Aug 10.

Department of Biostatistics, Jawaharlal Institute of Post-Graduate Medical Education and Research (JIPMER), Puducherry, India.

Purpose: To compare visual field test results of Glaufield Lite AP901 CTS 133 (Appasamy Associates, Mannadipet Commune, Thirubhuvanai, Puducherry, India, hereafter Glaufield Lite) with Humphrey Field Analyser (HFA, Carl Zeiss Meditec, Dublin, California, USA, hereafter HFA).

Methods: A pilot study at a tertiary eye centre involving 23 normal and 24 glaucoma patients who underwent two consecutive visual field tests on (i) HFA 24-2 SITA Fast and (ii) Glaufield Lite Quick Central program.

Results: The mean testing time on HFA was significantly shorter than Glaufield Lite (normals: HFA: 2. Read More

View Article and Full-Text PDF

Automated Bonding Analysis with Crystal Orbital Hamilton Populations.

Chempluschem 2022 Aug 10:e202200246. Epub 2022 Aug 10.

Université Catholique de Louvain, Institute of Condensed Matter and Nanosciences, Chemin des Étoiles 8, 1348, Louvain-la-Neuve, Belgium.

Invited for this month's cover are researchers from Bundesanstalt für Materialforschung und -prüfung (Federal Institute for Materials Research and Testing) in Germany, Friedrich Schiller University Jena, Université catholique de Louvain, University of Oregon, Science & Technology Facilities Council, RWTH Aachen University, Hoffmann Institute of Advanced Materials, and Dartmouth College. The cover picture shows a workflow for automatic bonding analysis with Python tools (green python). The bonding analysis itself is performed with the program LOBSTER (red lobster). Read More

View Article and Full-Text PDF

Effect of ambient temperature on average daily gain of pigs evaluated using public weather data and a plateau-linear regression model.

Anim Sci J 2022 Jan;93(1):e13762

Graduate School of Agricultural Science, Tohoku University, Sendai, Japan.

We performed a plateau-linear regression model analysis of the average daily gain (ADG) of pigs on daily average temperature at the end of performance testing (T). Records for performance testing between 30 kg and 105 kg of 2268 purebred Duroc pigs raised at the National Livestock Breeding Center Miyazaki Station were used. Off-farm ambient temperatures were measured at the nearest Automated Meteorological Data Acquisition System station at Kobayashi, Miyazaki (Kobayashi station). Read More

View Article and Full-Text PDF
January 2022

Olfactory perception in patients with a mild traumatic brain injury: a longitudinal study.

Brain Inj 2022 Aug 9:1-6. Epub 2022 Aug 9.

Research Center of the Hôpital du Sacré-Cœur de Montréal, Montreal, QC, Canada.

Objective: This longitudinal study aimed to evaluate olfactory perception in patients with first time mild traumatic brain injury (mTBI) 2-4 weeks (baseline) and 6 months (follow-up) following their trauma.

Methods: At baseline, we enrolled 107 participants (54 healthy controls; 53 patients with mTBI). Thirty-nine healthy controls and 32 patients with mTBI returned for follow-up. Read More

View Article and Full-Text PDF

Fully automated breast segmentation on spiral breast computed tomography images.

J Appl Clin Med Phys 2022 Aug 9:e13726. Epub 2022 Aug 9.

Institute of Diagnostic and Interventional Radiology, University Hospital of Zurich, Zurich, Switzerland.

Introduction: The quantification of the amount of the glandular tissue and breast density is important to assess breast cancer risk. Novel photon-counting breast computed tomography (CT) technology has the potential to quantify them. For accurate analysis, a dedicated method to segment the breast components-the adipose and glandular tissue, skin, pectoralis muscle, skinfold section, rib, and implant-is required. Read More

View Article and Full-Text PDF

Detection of COVID-19 from chest X-ray images: Boosting the performance with convolutional neural network and transfer learning.

Expert Syst 2022 Jul 29. Epub 2022 Jul 29.

Key Laboratory for Information Photonic Technology of Shaanxi Province and Key Laboratory for Physical Electronics and Devices of the Ministry of Education, School of Electronic Science and Engineering, Faculty of Electronic and Information Engineering Xi'an Jiaotong University Xi'an Shaanxi China.

Coronavirus disease (COVID-19) is a pandemic that has caused thousands of casualties and impacts all over the world. Most countries are facing a shortage of COVID-19 test kits in hospitals due to the daily increase in the number of cases. Early detection of COVID-19 can protect people from severe infection. Read More

View Article and Full-Text PDF

Randomized feasibility trial of the Scleroderma Patient-centered Intervention Network hand exercise program (SPIN-HAND).

PeerJ 2022 4;10:e13471. Epub 2022 Aug 4.

Service de Médecine Interne, Centre de Référence Maladies Autoimmunes Systémiques Rares d'Ile de France, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.

Purpose: The Scleroderma Patient-centered Intervention Network (SPIN) online hand exercise program (SPIN-HAND), is an online self-help program of hand exercises designed to improve hand function for people with scleroderma. The objective of this feasibility trial was to evaluate aspects of feasibility for conducting a full-scale randomized controlled trial of the SPIN-HAND program.

Materials And Methods: The feasibility trial was embedded in the SPIN cohort and utilized the cohort multiple randomized controlled trial (cmRCT) design. Read More

View Article and Full-Text PDF

Development and validation of a clinicoradiomic nomogram to assess the HER2 status of patients with invasive ductal carcinoma.

BMC Cancer 2022 Aug 10;22(1):872. Epub 2022 Aug 10.

Department of Radiology, The Central Hospital Affiliated to Shaoxing University (Shaoxing Central Hospital), Shaoxing, 312030, China.

Background: The determination of HER2 expression status contributes significantly to HER2-targeted therapy in breast carcinoma. However, an economical, efficient, and non-invasive assessment of HER2 is lacking. We aimed to develop a clinicoradiomic nomogram based on radiomics scores extracted from multiparametric MRI (mpMRI, including ADC-map, T2W1, DCE-T1WI) and clinical risk factors to assess HER2 status. Read More

View Article and Full-Text PDF

Online patient feedback as a safety valve: An automated language analysis of unnoticed and unresolved safety incidents.

Risk Anal 2022 Aug 9. Epub 2022 Aug 9.

Department of Psychological & Behavioural Science, London School of Economics, London, UK.

Safety reporting systems are widely used in healthcare to identify risks to patient safety. But, their effectiveness is undermined if staff do not notice or report incidents. Patients, however, might observe and report these overlooked incidents because they experience the consequences, are highly motivated, and independent of the organization. Read More

View Article and Full-Text PDF

Do-it-yourself and Commercial Automated Insulin Delivery Systems in Type 1 Diabetes: An Uncertain Area for Canadian Healthcare Providers.

Can J Diabetes 2022 Jun 22. Epub 2022 Jun 22.

Division of Endocrinology and Metabolism, Department of Medicine, Walter C. MacKenzie Health Sciences Centre, University of Alberta, Edmonton, Alberta, Canada.

In the past century, since the discovery of insulin, methods of insulin delivery and glucose monitoring have advanced technologically. In particular, the introduction of insulin pumps, providing continuous subcutaneous insulin infusion (CSII), and continuous glucose monitors (CGM) have been revolutionary for people living with type 1 diabetes. In this review, we have focussed on automated insulin delivery (AID) systems and discuss the implications of both approved and off-label options for the user and healthcare providers. Read More

View Article and Full-Text PDF

A rare case of clinically significant naturally occurring anti-C reported in a healthy male donor.

Transfus Clin Biol 2022 Aug 6. Epub 2022 Aug 6.

Transfusion Medicine & Blood centre, Jaypee Hospital, Noida, Delhi NCR, India. Electronic address:

Anti-C antibody is an immunoglobulin against the red cell antigen C which is a low frequency red cell antigen that belongs to the Rh antigen system. It is a clinically significant antibody and may cause haemolysis on exposure to antigen positive red cells. Due to its low frequency, it is not included in routine antibody screening panels. Read More

View Article and Full-Text PDF

Effective cleaning and decontamination of the internal air and water channels, heads and head-gears of multiple contra angle dental handpieces using an enzymatic detergent and automated washer disinfection in a dental hospital setting.

J Hosp Infect 2022 Aug 6. Epub 2022 Aug 6.

University of Dublin Trinity College, Microbiology Research Unit, Division of Oral Biosciences, Dublin Dental University Hospital, Lincoln Place, Dublin D02 F859, Ireland. Electronic address:

Background: Dental handpieces (DHPs) are reusable invasive medical devices that must be cleaned, decontaminated, lubricated and steam sterilized after use. DHPs have a complex internal design including narrow channels, contamination of which can compromise sterilization. DHPs are not designed for routine disassembly, making cleaning/decontamination efficacy difficult to monitor. Read More

View Article and Full-Text PDF

[Preparation of doses to be administered : there is automated machine and automated machine].

Demange Claude

Ann Pharm Fr 2022 Aug 6. Epub 2022 Aug 6.

Pharmacien Praticien Hospitalier Chef de Service, Service Pharmacie - Centre Hospitalier de Saint-Dié des Vosges, 26 rue du Nouvel Hôpital, 88100 Saint Dié Des Vosges, France. Electronic address:

The new reference system of the national council of the order of pharmacists relating to pharmacies for internal use, endorses the use of deconditioning machines. The authors express their disagreement by promoting the use of over-conditioning automatons and explain the reasons for this. They call for a debate. Read More

View Article and Full-Text PDF

High-throughput screening paradigms in ecotoxicity testing: Emerging prospects and ongoing challenges.

Chemosphere 2022 Aug 6:135929. Epub 2022 Aug 6.

LemnaTec GmbH, Nerscheider Weg 170, 52076, Aachen, Germany.

The rapidly increasing number of new production chemicals coupled with stringent implementation of global chemical management programs necessities a paradigm shift towards boarder uses of low-cost and high-throughput ecotoxicity testing strategies as well as deeper understanding of cellular and sub-cellular mechanisms of ecotoxicity that can be used in effective risk assessment. The latter will require automated acquisition of biological data, new capabilities for big data analysis as well as computational simulations capable of translating new data into in vivo relevance. However, very few efforts have been so far devoted into the development of automated bioanalytical systems in ecotoxicology. Read More

View Article and Full-Text PDF

Comparison of simulated candidemia detection during prophylactic antifungal therapy.

Diagn Microbiol Infect Dis 2022 Jul 16;104(2):115768. Epub 2022 Jul 16.

Department of Laboratory Medicine, Chung-Ang University College of Medicine, Seoul, Republic of Korea. Electronic address:

Background: We investigated the neutralization performance of various automated blood culture systems for antifungal agents with regard to the most commonly isolated Candida species.

Methods: In this study, we evaluated the time to detection (TTD) of simulated candidemia for 6 Candida spp. (C. Read More

View Article and Full-Text PDF

Semi-automated detection of ungulates using UAV imagery and reflective spectrometry.

J Environ Manage 2022 Aug 6;320:115807. Epub 2022 Aug 6.

Czech University of Life Sciences Prague, Faculty of Tropical AgriSciences, Kamýcká 129, Praha-Suchdol, 165 00, Czech Republic.

In the field of species conservation, the use of unmanned aerial vehicles (UAV) is increasing in popularity as wildlife observation and monitoring tools. With large datasets created by UAV-based species surveying, the need arose to automate the detection process of the species. Although the use of computer learning algorithms for wildlife detection from UAV-derived imagery is an increasing trend, it depends on a large amount of imagery of the species to train the object detector effectively. Read More

View Article and Full-Text PDF

Accurate and Efficient Calculation of the Solution Enthalpy and Diffusivity of Solutes in Liquid Metals Using Machine Learning Potential.

J Chem Theory Comput 2022 Aug 9. Epub 2022 Aug 9.

Department of Nuclear Engineering, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea.

Liquid metals (LMs) have various applications in energy systems, such as coolants in advanced nuclear reactors. In addition, room-temperature LMs are attracting attention as flexible components in robotics and electronics and as novel chemical reaction media to form low-dimensional materials. In many of these applications, the capabilities of LMs can be further enhanced if one can better understand and control the chemical reactivity of LMs, which is largely affected by the stability and mobility of solutes in LMs. Read More

View Article and Full-Text PDF

Opioid prescriptions for individuals receiving workers' compensation in Michigan.

PLoS One 2022 9;17(8):e0272385. Epub 2022 Aug 9.

Department of Medicine, Michigan State University, East Lansing, Michigan, United States of America.

Purpose: We evaluated the prevalence of opioid prescriptions after injury and associated characteristics among workers receiving workers' compensation for a lost work time injury.

Methods: Injured workers identified in Michigan's Workers' Compensation records from 2016 to 2018 were linked to the opioid prescription history in the Michigan Automated Prescription System.

Results: Among the 46,934 injured workers with paid claims, the prevalence of receiving an opioid prescription, morphine milligram equivalents (MME) per prescription, number of opioid prescription and probability of receiving opioids prescription>90 days after injury decreased from 2016-2018. Read More

View Article and Full-Text PDF

Effects of Feedback From Self-Monitoring Devices on Lifestyle Changes in Workers with Diabetes: 3-Month Randomized Controlled Pilot Trial.

JMIR Form Res 2022 Aug 9;6(8):e23261. Epub 2022 Aug 9.

Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan.

Background: Although lifestyle interventions are useful in the prevention and management of diabetes, they can be expensive and time-consuming. There is some evidence on the effectiveness of automated mobile technology for health self-monitoring; however, few studies have used such devices in the occupational health field.

Objective: We aimed to examine the effectiveness of a digital self-monitoring device on glucose levels and activity of workers with diabetes in Japan. Read More

View Article and Full-Text PDF

Magistral Compounding with 3D Printing: A Promising Way to Achieve Personalized Medicine.

Ther Innov Regul Sci 2022 Aug 9. Epub 2022 Aug 9.

Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.

Background: Magistral compounding has always been an integral part of pharmacy practice. The increasing demand worldwide for personalized drug treatments might be accommodated by an increase in magistral compounding. The new, flexible technology of 3D medicine printing could advance this process even further. Read More

View Article and Full-Text PDF

Current status and challenges of percutaneous vertebroplasty (PVP).

Jpn J Radiol 2022 Aug 9. Epub 2022 Aug 9.

Department of Radiology, National Hospital Organization Kyushu Medical Center, 1-8-1 Jigyohama, Chuo-ku, Fukuoka City, Fukuoka Province, 810-8563, Japan.

A narrative review regarding percutaneous vertebroplasty (PVP) for osteoporotic vertebral fracture (OVF) is provided herein, addressing the epidemic of OVF in Japan, the latest response to the criticism of PVP for OVFs, the indications and potential risks of PVP for OVFs, and a future perspective for PVP. Each year in Japan, approximately 32,000 patients aged 55 years or older suffer from chronic low back pain for several months to several years due to a compression fracture. PVP is one of the surgical treatments for an OVF, and it is less invasive compared to the traditional open surgery. Read More

View Article and Full-Text PDF

Initial emergency department vital signs may predict PICU admission in pediatric patients presenting with asthma exacerbation.

J Asthma 2022 Aug 9:1-13. Epub 2022 Aug 9.

Division of Pulmonary Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA.

Objective: Severe asthma exacerbations account for a large share of asthma morbidity, mortality, and costs. Here, we aim to identify early predictive factors associated with pediatric intensive care unit (PICU) admission.

Methods: We performed a retrospective observational study of 5,185 emergency department (ED) encounters at a large children's hospital, including 86 (1. Read More

View Article and Full-Text PDF

A rotation invariant template matching algorithm based on Sub-NCC.

Math Biosci Eng 2022 Jun;19(9):9505-9519

School of Mechanical and Electrical Engineering, Guangzhou University, Guangzhou 511400, China.

This paper proposes an anti-rotation template matching method based on a portion of the whole pixels. To solve the problem that the speed of the original template matching method based on NCC (Normalized cross correlation) is too slow for the rotated image, a template matching method based on Sub-NCC is proposed, which improves the anti-jamming ability of the algorithm. At the same time, in order to improve the matching speed, the rotation invariant edge points are selected from the rotation invariant pixels, and the selected points are used for rough matching to quickly screen out the unmatched areas. Read More

View Article and Full-Text PDF

Reversible Corneal Decompensation Caused by a Topical Dorzolamide/Timolol Fixed Combination After Descemet Stripping Automated Endothelial Keratoplasty.

Cornea 2022 Sep 19;41(9):1171-1173. Epub 2021 Oct 19.

Department of Ophthalmology, Keimyung University School of Medicine, Dongsan Medical Center, Daegu, Korea.

Purpose: The purpose of this study was to report a case of acute corneal endothelial decompensation caused by a topical dorzolamide/timolol fixed combination (DTFC) after Descemet stripping automated endothelial keratoplasty.

Methods: A 75-year-old woman who was referred to our hospital with a chief complaint of visual disturbance in the right eye after cataract surgery. Anterior segment optical coherence tomography identified an extensive defect in Descemet membrane. Read More

View Article and Full-Text PDF
September 2022