The effect of non-TNF-targeted biologics and small molecules on insulin resistance in inflammatory arthritis.
- Francesco Ursini,
- Emilio Russo,
- Piero Ruscitti,
- Roberto Giacomelli,
- Giovambattista De Sarro
Autoimmun Rev 2018 Feb 13. Epub 2018 Feb 13.
Department of Health Sciences, University of Catanzaro "Magna Graecia", Catanzaro, Italy.
Inflammatory arthritides are chronic diseases characterised by an increase in cardiovascular risk, largely attributable to the synergy between high-grade systemic inflammation and an elevated prevalence of traditional cardiovascular risk factors. Amongst the latter, insulin resistance and type 2 diabetes (T2D) play a key position. Previous studies demonstrated a potential insulin-sensitizing effect of anti-TNF biologic medications. Read More