123 results match your criteria Autism research and treatment[Journal]


Risk for ASD in Preterm Infants: A Three-Year Follow-Up Study.

Autism Res Treat 2018 11;2018:8316212. Epub 2018 Nov 11.

Department of Psychology, The Hebrew University of Jerusalem, Mount Scopus, Jerusalem, 91905, Israel.

Background: The aim of this study was to examine the long-term risk for autism spectrum disorders (ASD) in individuals who are born preterm and full-term using both observational instruments and parental reports. Neonatal risk factors and developmental characteristics associated with ASD risk were also examined.

Method: Participants included 110 preterm children (born at a gestational age of ≤ 34 weeks) and 39 full-term children assessed at ages 18, 24, and 36 months. Read More

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http://dx.doi.org/10.1155/2018/8316212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252203PMC
November 2018
1 Read

Neuromagnetic Beta-Band Oscillations during Motor Imitation in Youth with Autism.

Autism Res Treat 2018 25;2018:9035793. Epub 2018 Jul 25.

Department of Psychology, Colorado State University, Fort Collins, CO, USA.

Children with ASD often exhibit early difficulties with action imitation, possibly due to low-level sensory or motor impairments. Impaired cortical rhythms have been demonstrated in adults with ASD during motor imitation. While those oscillations reflect an age-dependent process, they have not been fully investigated in youth with ASD. Read More

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http://dx.doi.org/10.1155/2018/9035793DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083595PMC

Role of Inner Speech on Serial Recall in Children with ASD: A Pilot Study Using the Luria Hand Test.

Autism Res Treat 2018 14;2018:6873412. Epub 2018 Mar 14.

Faculty of Education, Tokyo Gakugei University, 4-1-1 Nukuikita-machi, Koganei City, Tokyo 184-8501, Japan.

This study was conducted to investigate the relation between the effect of articulatory suppression on the serial recall and severity of social impairments among children with autism spectrum disorders (ASD). The Luria hand test (LHT) was administered to evaluate the capacity for serial recall in 13 children with ASD. The LHT was administered under three conditions: control, under articulatory suppression, and under spatial suppression. Read More

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http://dx.doi.org/10.1155/2018/6873412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872676PMC

A Study of the Correlation between VEP and Clinical Severity in Children with Autism Spectrum Disorder.

Autism Res Treat 2018 14;2018:5093016. Epub 2018 Jan 14.

Research Center for Neuroscience, Institute of Molecular Biosciences, Mahidol University, Nakhon Pathom 73170, Thailand.

Visual evoked potential (VEP) is a technique used to assess the brain's electrical response to visual stimuli. The aims of this study were to examine neural transmission within the visual pathway through VEP testing in preschool children with autism spectrum disorder (ASD) and compare it to age-matched controls, as well as search for a correlation between the VEP parameters and the symptoms of ASD. Participants were composed of ASD children (9 males) and typically developing children (8 males and 4 females), aged between 3 and 5 years. Read More

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http://dx.doi.org/10.1155/2018/5093016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820569PMC
January 2018

Support Needs and Coping Strategies as Predictors of Stress Level among Mothers of Children with Autism Spectrum Disorder.

Autism Res Treat 2017 25;2017:8685950. Epub 2017 Dec 25.

Simmons College, Boston, MA, USA.

This study examined maternal stress, coping strategies, and support needs among mothers of children with Autism Spectrum Disorder (ASD). A convenience sample of 70 mothers completed the Parent Stress Index Short Form (PSI-SF), Coping Health Inventory for Parents (CHIP), and Modified Family Needs Questionnaire (FNQ). PSI-SF scores reflected clinically significant levels of stress for 77% of mothers, and mothers identified 62. Read More

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http://dx.doi.org/10.1155/2017/8685950DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757090PMC
December 2017
4 Reads

Associations between Familial Rates of Psychiatric Disorders and De Novo Genetic Mutations in Autism.

Autism Res Treat 2017 8;2017:9371964. Epub 2017 Nov 8.

Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 91895, USA.

The purpose of this study was to examine the confluence of genetic and familial risk factors in children with Autism Spectrum Disorder (ASD) with distinct de novo genetic events. We hypothesized that gene-disrupting mutations would be associated with reduced rates of familial psychiatric disorders relative to structural mutations. Participants included families of children with ASD in four groups: de novo duplication copy number variations (DUP, = 62), de novo deletion copy number variations (DEL, = 74), de novo likely gene-disrupting mutations (LGDM, = 267), and children without a known genetic etiology (NON, = 2111). Read More

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http://dx.doi.org/10.1155/2017/9371964DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698792PMC
November 2017
5 Reads

Social Skills Intervention Participation and Associated Improvements in Executive Function Performance.

Autism Res Treat 2017 17;2017:5843851. Epub 2017 Sep 17.

Department of Special Education, University of Missouri, Columbia, MO, USA.

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social communication. It has been postulated that such difficulties are related to disruptions in underlying cognitive processes such as executive function. The present study examined potential changes in executive function performance associated with participation in the Social Competence Intervention (SCI) program, a short-term intervention designed to improve social competence in adolescents with ASD. Read More

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http://dx.doi.org/10.1155/2017/5843851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623786PMC
September 2017
7 Reads

Longitudinal Study of Sensory Features in Children with Autism Spectrum Disorder.

Autism Res Treat 2017 27;2017:1934701. Epub 2017 Aug 27.

École de Réadaptation, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, QC, Canada J1H 5N4.

Background: Between 45 and 95% of children with Autism Spectrum Disorder (ASD) present sensory features that affect their daily functioning. However, the data in the scientific literature are not conclusive regarding the evolution of sensory features in children with ASD. The main objective of this study was to analyze the sensory features of children within the age of 3-4 (T1) when they received their ASD diagnosis and two years later (T2) when they started school. Read More

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http://dx.doi.org/10.1155/2017/1934701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592014PMC
August 2017
26 Reads

Neuropsychological Characteristics of Children with Mixed Autism and ADHD.

Autism Res Treat 2017 25;2017:5781781. Epub 2017 Jul 25.

University of Michigan, Ann Arbor, MI, USA.

Clinical heterogeneity is a well-established characteristic of autism spectrum disorder (ASD). While the comorbidity of ASD and ADHD is well known in clinical practice, relatively little research has examined the neuropsychological profile of children with ASD + ADHD. Our study showed significant differences in the neuropsychological characteristics of children with ASD + ADHD compared to those with ASD only. Read More

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http://dx.doi.org/10.1155/2017/5781781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547727PMC
July 2017
1 Read

The 2D : 4D Digit Ratio as a Biomarker for Autism Spectrum Disorder.

Autism Res Treat 2017 19;2017:1048302. Epub 2017 Jul 19.

Division of Pharmacology, Utrecht University, Utrecht, Netherlands.

It has been suggested that the second (2D, index finger) to fourth (4D, ring finger) digit ratio, 2D : 4D, may be a biomarker for the risk of developing autism. The aim of the current study was to determine the usefulness of the 2D : 4D digit ratio as biomarker for autistic traits. = 401 healthy young volunteers participated in the study. Read More

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https://www.hindawi.com/journals/aurt/2017/1048302/
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http://dx.doi.org/10.1155/2017/1048302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540470PMC
July 2017
6 Reads

Investigating the Evidence of Behavioral, Cognitive, and Psychiatric Endophenotypes in Autism: A Systematic Review.

Autism Res Treat 2017 5;2017:6346912. Epub 2017 Jul 5.

Department of Psychiatry, University of Oxford, Oxford, UK.

Substantial evidence indicates that parents of autistic individuals often display milder forms of autistic traits referred to as the broader autism phenotype (BAP). To determine if discrete endophenotypes of autism can be identified, we reviewed the literature to assess the evidence of behavioral, cognitive, and psychiatric profiles of the BAP. A systematic review was conducted using EMBASE, MEDLINE, PsycINFO, PsycEXTRA, and Global Health. Read More

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http://dx.doi.org/10.1155/2017/6346912DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516739PMC
July 2017
4 Reads

Autistic Traits Affect P300 Response to Unexpected Events, regardless of Mental State Inferences.

Autism Res Treat 2017 4;2017:8195129. Epub 2017 Jun 4.

Graduate School of Environmental Studies, Nagoya University, Nagoya, Japan.

Limited use of contextual information has been suggested as a way of understanding cognition in people with autism spectrum disorder (ASD). However, it has also been argued that individuals with ASD may have difficulties inferring others' mental states. Here, we examined how individuals with different levels of autistic traits respond to contextual deviations by measuring event-related potentials that reflect context usage. Read More

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http://dx.doi.org/10.1155/2017/8195129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474239PMC

Initial Development of the Early Intensive Behavioral Intervention Parental Self-Efficacy Scale: A Pilot Study.

Autism Res Treat 2017 31;2017:9512180. Epub 2017 May 31.

Capella University, Minneapolis, MN, USA.

Early Intensive Behavioral Intervention (EIBI) is an effective treatment for children with autism. However, it is known that some parents struggle to fully implement the program, and providers are not always able to identify the specifics of each family's individualized challenges. The purpose of this pilot study was to begin the process of developing a new instrument, the EIBI Parental Self-Efficacy (EPSE) Scale, to help providers better assess and assist parents in regard to EIBI implementation. Read More

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http://dx.doi.org/10.1155/2017/9512180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469979PMC
May 2017
5 Reads

Autism Spectrum Disorder Screening Instruments for Very Young Children: A Systematic Review.

Autism Res Treat 2016 26;2016:4624829. Epub 2016 Dec 26.

Westchester Institute for Human Development, Valhalla, NY, USA; School of Health Sciences & Practice, New York Medical College, Valhalla, NY, USA; Department of Pediatrics, New York Medical College, Valhalla, NY, USA.

Research on ASD in infancy has provided a rationale for developing screening instruments for children from the first year of life to age of 18 months. A comprehensive literature search identified candidate screening tools. Using methodological probe questions adapted from the Quality Assessment of Diagnostic Accuracy Studies (QUADAS), two Level 1 and three Level 2 screening instruments were reviewed in detail. Read More

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http://dx.doi.org/10.1155/2016/4624829DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220395PMC
December 2016
1 Read

A Preliminary Investigation of a Specialized Music Therapy Model for Children with Disabilities Delivered in a Classroom Setting.

Autism Res Treat 2016 23;2016:1284790. Epub 2016 Nov 23.

Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC, USA.

Music therapy is gaining popularity as an intervention strategy for children with developmental disabilities, including autism spectrum disorder (ASD). This study was a pilot investigation of a classroom-based music-based intervention, , for improving communication skills in children with ASD and children with intellectual disabilities. Four local public elementary school special education classrooms, serving 5 children with a classification of autistic disorder and 32 children with intellectual disability without autism, were randomly selected to receive one of two levels of exposure to music therapy: "long-term" (15 weeks beginning in January 2015 (Time 1), = 14) or "short-term" (7 weeks beginning 7 weeks later in February (Time 2), = 17). Read More

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http://dx.doi.org/10.1155/2016/1284790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141315PMC
November 2016
2 Reads

What Do Parents Think about Chromosomal Microarray Testing? A Qualitative Report from Parents of Children with Autism Spectrum Disorders.

Autism Res Treat 2016 20;2016:6852539. Epub 2016 Jun 20.

Department of Health Education and Promotion, College of Health and Human Performance, East Carolina University, Greenville, NC 27858, USA.

Background. Chromosomal Microarray Analysis (CMA) is increasingly utilized to detect copy number variants among children and families affected with autism spectrum disorders (ASD). However, CMA is controversial due to possible ambiguous test findings, uncertain clinical implications, and other social and legal issues related to the test. Read More

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http://dx.doi.org/10.1155/2016/6852539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931081PMC
July 2016
3 Reads

Calcium and Vitamin D Supplement Prescribing Practices among Providers Caring for Children with Autism Spectrum Disorders: Are We Addressing Bone Health?

Autism Res Treat 2016 6;2016:6763205. Epub 2016 Mar 6.

Pediatric Endocrinology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

Children with autism spectrum disorders (ASD) have several risk factors for low bone mineral density. The gluten-free, casein-free (GFCF) diet is a complementary therapy sometimes used in ASD that raises concerns for the adequacy of calcium and vitamin D intake. This study evaluated the prescribing practices of calcium and vitamin D supplements and the practice of checking 25-hydroxy vitamin D (25(OH)D) levels by providers in 100 children with ASD, 50 of whom were on the GFCF diet. Read More

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http://dx.doi.org/10.1155/2016/6763205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799806PMC
April 2016
4 Reads

The Association between Adult Participation and the Engagement of Preschoolers with ASD.

Autism Res Treat 2016 24;2016:6029837. Epub 2016 Feb 24.

Frank Porter Graham Child Development Institute, University of North Carolina, Chapel Hill, 517 S. Greensboro Road, Carrboro, NC 27510, USA.

The ability for a child to engage in the classroom is associated with better academic outcomes. Yet, there is limited information on how child characteristics of autism and adult behavior impact engagement. This study examined (1) the pattern of adult participation and child engagement in preschool classrooms that serve children with ASD, (2) the associations between child engagement and adult participation, and (3) how characteristics of ASD (autism severity, language ability, and challenging behavior) moderate the relationship between adult participation and child engagement. Read More

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http://dx.doi.org/10.1155/2016/6029837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783529PMC
March 2016
47 Reads

Factor Structure, Internal Consistency, and Screening Sensitivity of the GARS-2 in a Developmental Disabilities Sample.

Autism Res Treat 2016 15;2016:8243079. Epub 2016 Feb 15.

Department of Counseling, Educational Psychology, and Special Education, College of Education, Michigan State University, East Lansing, MI 48824-1034, USA.

The Gilliam Autism Rating Scale-Second Edition (GARS-2) is a widely used screening instrument that assists in the identification and diagnosis of autism. The purpose of this study was to examine the factor structure, internal consistency, and screening sensitivity of the GARS-2 using ratings from special education teaching staff for a sample of 240 individuals with autism or other significant developmental disabilities. Exploratory factor analysis yielded a correlated three-factor solution similar to that found in 2005 by Lecavalier for the original GARS. Read More

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http://dx.doi.org/10.1155/2016/8243079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770117PMC
March 2016
16 Reads

An Analysis of Canadian Institute for Health Research Funding for Research on Autism Spectrum Disorder.

Autism Res Treat 2016 10;2016:8106595. Epub 2016 Feb 10.

Interdisciplinary School of Health Sciences, Faculty of Health Sciences, University of Ottawa, 25 University Private, THN 208, Ottawa, ON, Canada K1N 6N5; School of Psychology, Faculty of Social Sciences, University of Ottawa, Ottawa, ON, Canada K1N 6N5.

We examined patterns of Canadian Institute for Health Research (CIHR) funding on autism spectrum disorder (ASD) research. From 1999 to 2013, CIHR funded 190 ASD grants worth $48 million. Biomedical research received 43% of grants (46% of dollars), clinical research 27% (41%), health services 10% (7%), and population health research 8% (3%). Read More

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http://dx.doi.org/10.1155/2016/8106595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764728PMC

Illness Severity, Social and Cognitive Ability, and EEG Analysis of Ten Patients with Rett Syndrome Treated with Mecasermin (Recombinant Human IGF-1).

Autism Res Treat 2016 26;2016:5073078. Epub 2016 Jan 26.

Tuscany Rett Center, Ospedale Versilia, 55043 Lido di Camaiore, Italy; Department of Psychiatry, Trinity College Dublin, College Green, Dublin 2, Ireland; Neuropsychiatric Genetics, Trinity Centre for Health Sciences, St. James Hospital, Dublin 8, Ireland.

Rett Syndrome (RTT) is a severe neurodevelopmental disorder characterized by an apparently normal development followed by an arrest and subsequent regression of cognitive and psychomotor abilities. At present, RTT has no definitive cure and the treatment of RTT represents a largely unmet clinical need. Following partial elucidation of the underlying neurobiology of RTT, a new treatment has been proposed, Mecasermin (recombinant human Insulin-Like Growth Factor 1), which, in addition to impressive evidence from preclinical murine models of RTT, has demonstrated safety in human studies of patients with RTT. Read More

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http://dx.doi.org/10.1155/2016/5073078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746298PMC
February 2016
22 Reads

Theory of Mind Indexes the Broader Autism Phenotype in Siblings of Children with Autism at School Age.

Autism Res Treat 2016 10;2016:6309189. Epub 2016 Jan 10.

Department of Psychiatry & Bio-Behavioral Sciences, David Geffen School of Medicine at UCLA, University of California, Los Angeles, CA 90024, USA.

Subclinical variants of the social-communicative challenges and rigidity that define autism spectrum disorder (ASD) are known as the broader autism phenotype (BAP). The BAP has been conceptualized categorically (as specific to a subset of relatives of individuals with ASD) and dimensionally (as continuously distributed within the general population). The current study examined the compatibility of these two approaches by assessing associations among autism symptoms and social-communicative skills in young school-age children with ASD, children who have a sibling with ASD, and children without a sibling with ASD. Read More

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http://dx.doi.org/10.1155/2016/6309189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736958PMC
February 2016
3 Reads

Neural Mechanisms Involved in Hypersensitive Hearing: Helping Children with ASD Who Are Overly Sensitive to Sounds.

Autism Res Treat 2015 28;2015:369035. Epub 2015 Dec 28.

Advanced Brain Technologies, Ogden, UT, USA.

Professionals working with children diagnosed with autism spectrum disorder (ASD) may find that these children are overly sensitive to sounds. These professionals are often concerned as to why children may have auditory hypersensitivities. This review article discusses the neural mechanisms identified underlying hypersensitive hearing in people. Read More

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http://dx.doi.org/10.1155/2015/369035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707379PMC
January 2016
1 Read

The Effects of Rhythm and Robotic Interventions on the Imitation/Praxis, Interpersonal Synchrony, and Motor Performance of Children with Autism Spectrum Disorder (ASD): A Pilot Randomized Controlled Trial.

Autism Res Treat 2015 17;2015:736516. Epub 2015 Dec 17.

Department of Physical Therapy, Biomechanics and Movement Sciences, University of Delaware, Newark, DE 19713, USA; Physical Therapy Program, Department of Kinesiology, University of Connecticut, Storrs, CT 06269, USA; Center for Health, Intervention, and Prevention, Department of Psychology, University of Connecticut, Storrs, CT 06269, USA; Behavioral Neuroscience Program, Department of Psychology, University of Delaware, Newark, DE 19713, USA.

We assessed the effects of three interventions, rhythm, robotic, and standard-of-care, on the imitation/praxis, interpersonal synchrony, and overall motor performance of 36 children with Autism Spectrum Disorder (ASD) between 5 and 12 years of age. Children were matched on age, level of functioning, and services received, prior to random assignment to one of the three groups. Training was provided for 8 weeks with 4 sessions provided each week. Read More

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http://dx.doi.org/10.1155/2015/736516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697072PMC
January 2016
13 Reads

Video Game Playing Effects on Obesity in an Adolescent with Autism Spectrum Disorder: A Case Study.

Autism Res Treat 2015 10;2015:128365. Epub 2015 Dec 10.

University of Florida, College of Nursing, P.O. Box 100187, Gainesville, FL 32610-0187, USA.

Adolescent obesity has tripled in the past two decades, and adolescents with disabilities, specifically autism spectrum disorders (ASD), may be at greater risk for obesity due to the behavioral, physical, and psychosocial complications related to their disorder. This case study reports the effects of video game playing on an obese adolescent with ASD and illustrates the use of a multiple baseline single subject design. Over 12 weeks, the participant played inactive (6 weeks) and active video games (6 weeks) on the Wii console. Read More

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http://dx.doi.org/10.1155/2015/128365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689879PMC
January 2016

Characteristics of Two-Year College Students on the Autism Spectrum and Their Support Services Experiences.

Autism Res Treat 2015 15;2015:391693. Epub 2015 Nov 15.

SRI International, 333 Ravenswood Avenue, BS 162, Menlo Park, CA 94025-3493, USA.

Approximately 80% of college-going youth with autism in the US attend a 2-year college at some point. These community-based, universally accessible institutions offer both academic and vocational courses and have experience in teaching diverse learners. This study used nationally representative survey data from the National Longitudinal Transition Study-2 to describe the characteristics and services experiences of adults with autism who attended postsecondary education after high school, focusing on those who attended a 2-year college. Read More

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http://dx.doi.org/10.1155/2015/391693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662964PMC
December 2015
23 Reads

About Face: Evaluating and Managing Tactile Impairment at the Time of Autism Diagnosis.

Autism Res Treat 2015 28;2015:612507. Epub 2015 Oct 28.

Teaching Research Institute, Western Oregon University, Post Office Box 92, McMinnville, OR 97128, USA.

Evaluation for sensory impairment is a routine part of autism diagnosis. Sensory impairment of hearing, vision, or touch results in developmental delay and must be addressed before delay can resolve. Recent studies confirm that tactile impairment is present in autism and can be effectively treated with a tactile stimulation protocol. Read More

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http://dx.doi.org/10.1155/2015/612507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641176PMC
November 2015

Parenting Behavior in Mothers of Preschool Children with ASD: Development of a Self-Report Questionnaire.

Autism Res Treat 2015 29;2015:381236. Epub 2015 Oct 29.

Parenting and Special Education Research Unit, University of Leuven (KU Leuven), Leopold Vanderkelenstraat 32, P.O. Box 3765, 3000 Leuven, Belgium ; Leuven Autism Research (LAuRes), University of Leuven (KU Leuven), 3000 Leuven, Belgium.

Parents of young children with autism spectrum disorder (ASD) encounter many daily challenges and often experience much stress. However, little research exists about parenting behavior among these parents. With this study, we aim to address this gap. Read More

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http://dx.doi.org/10.1155/2015/381236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641949PMC
November 2015
3 Reads

Gaze Behavior of Children with ASD toward Pictures of Facial Expressions.

Autism Res Treat 2015 19;2015:617190. Epub 2015 May 19.

Department of Psychology, Keio University, 2-15-45 Mita, Minato-ku, Tokyo 108-0073, Japan ; CREST, Japan Science and Technology Agency, 4-1-8 Honcho, Kawaguchi-shi, Saitama 332-0012, Japan.

Atypical gaze behavior in response to a face has been well documented in individuals with autism spectrum disorders (ASDs). Children with ASD appear to differ from typically developing (TD) children in gaze behavior for spoken and dynamic face stimuli but not for nonspeaking, static face stimuli. Furthermore, children with ASD and TD children show a difference in their gaze behavior for certain expressions. Read More

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http://dx.doi.org/10.1155/2015/617190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452249PMC
June 2015
3 Reads

Gait deviations in children with autism spectrum disorders: a review.

Autism Res Treat 2015 2;2015:741480. Epub 2015 Apr 2.

Discipline of Physiotherapy, School of Medicine, Trinity College Dublin, Dublin, Ireland.

In recent years, it has become clear that children with autism spectrum disorders (ASDs) have difficulty with gross motor function and coordination, factors which influence gait. Knowledge of gait abnormalities may be useful for assessment and treatment planning. This paper reviews the literature assessing gait deviations in children with ASD. Read More

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http://www.hindawi.com/journals/aurt/2015/741480/
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http://dx.doi.org/10.1155/2015/741480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398922PMC
April 2015
3 Reads

Parent-Child Agreement Using the Spence Children's Anxiety Scale and a Thermometer in Children with Autism Spectrum Disorder.

Autism Res Treat 2015 2;2015:315495. Epub 2015 Apr 2.

Deakin Child Study Centre, School of Psychology, Deakin University, Melbourne Burwood Campus, 221 Burwood Highway, Burwood, VIC 3125, Australia.

Children with Autism Spectrum Disorder (ASD) experience high anxiety which often prompts clinical referral and requires intervention. This study aimed to compare parent and child reports on the Spence Children's Anxiety Scale (SCAS) and a child-reported "worry thermometer" in 88 children aged 8-13 years, 44 with ASD and 44 age, gender, and perceptual IQ matched typically developing children. There were no gender differences in child report on the SCAS and worry thermometers. Read More

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http://dx.doi.org/10.1155/2015/315495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398944PMC

Early Intervention with a Parent-Delivered Massage Protocol Directed at Tactile Abnormalities Decreases Severity of Autism and Improves Child-to-Parent Interactions: A Replication Study.

Autism Res Treat 2015 24;2015:904585. Epub 2015 Mar 24.

Sikhara Group, 3434 NW Savier Street, Portland, OR 97210, USA.

Tactile abnormalities are severe and universal in preschool children with autism. They respond well to treatment with a daily massage protocol directed at tactile abnormalities (QST massage for autism). Treatment is based on a model for autism proposing that tactile impairment poses a barrier to development. Read More

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http://dx.doi.org/10.1155/2015/904585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387906PMC
April 2015
4 Reads

Knowledge of Childhood Autism and Challenges of Management among Medical Doctors in Kaduna State, Northwest Nigeria.

Autism Res Treat 2015 23;2015:892301. Epub 2015 Mar 23.

Department of Psychiatry, ABUTH, Shika-Zaria 810001, Nigeria.

Autism is a neurodevelopmental disorder with serious implications in childhood. There is a significant gap in the identification and provision of health and social services for autism in Africa. The knowledge of autism among health care providers and identifying challenges associated with its management could facilitate bridging the gap and ensuring better outcomes. Read More

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http://dx.doi.org/10.1155/2015/892301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386291PMC

Preliminary efficacy of adapted responsive teaching for infants at risk of autism spectrum disorder in a community sample.

Autism Res Treat 2015 11;2015:386951. Epub 2015 Jan 11.

University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7122, USA.

This study examined the (a) feasibility of enrolling 12-month-olds at risk of ASD from a community sample into a randomized controlled trial, (b) subsequent utilization of community services, and (c) potential of a novel parent-mediated intervention to improve outcomes. The First Year Inventory was used to screen and recruit 12-month-old infants at risk of ASD to compare the effects of 6-9 months of Adapted Responsive Teaching (ART) versus referral to early intervention and monitoring (REIM). Eighteen families were followed for ~20 months. Read More

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http://dx.doi.org/10.1155/2015/386951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306223PMC
February 2015
3 Reads

Temporal Synchrony Detection and Associations with Language in Young Children with ASD.

Autism Res Treat 2014 29;2014:678346. Epub 2014 Dec 29.

Division of Occupational Sciences, CB No. 7122, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

Temporally synchronous audio-visual stimuli serve to recruit attention and enhance learning, including language learning in infants. Although few studies have examined this effect on children with autism, it appears that the ability to detect temporal synchrony between auditory and visual stimuli may be impaired, particularly given social-linguistic stimuli delivered via oral movement and spoken language pairings. However, children with autism can detect audio-visual synchrony given nonsocial stimuli (objects dropping and their corresponding sounds). Read More

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http://dx.doi.org/10.1155/2014/678346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295130PMC
January 2015
5 Reads

How sex of children with autism spectrum disorders and access to treatment services relates to parental stress.

Autism Res Treat 2014 14;2014:721418. Epub 2014 Dec 14.

Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA.

Parents of children with autism spectrum disorders (ASD) experience higher levels of stress in comparison to parents of neurotypical children and consequently are more susceptible to negative health and social outcomes (Dunn et al., 2001). However, less is known about how individual child characteristics impact stress levels in parents of children with ASD. Read More

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http://dx.doi.org/10.1155/2014/721418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279184PMC
January 2015
1 Read

Experiences of dental care and dental anxiety in adults with autism spectrum disorder.

Autism Res Treat 2014 28;2014:238764. Epub 2014 Oct 28.

Department of Clinical Neuroscience, Karolinska Institutet and Northern Stockholm Psychiatry, St. Göran Hospital, 112 81 Stockholm, Sweden.

Dental anxiety is associated with previous distressing dental experiences, such as lack of understanding of the dentist intentions, perceptions of uncontrollability and experiences of pain during dental treatment. People with autism spectrum disorder (ASD) are impaired in building flexible predictions and expectations, which is very much needed during a dental visit. The aims of the study were to investigate if people with ASD have more negative dental experiences and a higher level of dental anxiety compared to a matched control group. Read More

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http://dx.doi.org/10.1155/2014/238764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228704PMC
December 2014
2 Reads

Mild dermatoglyphic deviations in adolescents with autism spectrum disorders and average intellectual abilities as compared to typically developing boys.

Autism Res Treat 2014 19;2014:968134. Epub 2014 Nov 19.

Department of Developmental Psychology, Faculty of Psychology & Education, VU University Amsterdam, 1081 BT Amsterdam, The Netherlands.

Dermatoglyphics, ridge constellations on the hands and feet, are permanently formed by the second trimester of pregnancy. Consequently, they are considered "fossilized" evidence of a specific prenatal period. A high frequency of dermatoglyphic anomalies, or a high rate of dermatoglyphic asymmetry (discordance), is an indication of developmental instability (prenatal disturbances) prior to 24-week gestation. Read More

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http://dx.doi.org/10.1155/2014/968134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251361PMC
December 2014
3 Reads

A Randomised Control Trial of the Impact of a Computer-Based Activity Programme upon the Fitness of Children with Autism.

Autism Res Treat 2014 7;2014:419653. Epub 2014 Oct 7.

School of Health and Life Sciences, Northumbria University, Coach Lane Campus, Newcastle Upon Tyne NE7 7XA, UK.

The poor levels of fitness in children with autism are prompting concern for the children's future health. This study looked to assess if a computer-based activity programme could improve fitness levels (as reflected in cardiopulmonary function) of these children, and achieve a reduction in their body mass index. In a randomised controlled trial, 50 children with autism (of which 33 were under the age of 11 years and 39 were boys) were allocated to an intervention group which encouraged them to use the Nintendo Wii and the software package "Mario and Sonics at the Olympics" in addition to their routine physical education classes. Read More

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http://dx.doi.org/10.1155/2014/419653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220566PMC
November 2014

Physical activity and physical fitness of school-aged children and youth with autism spectrum disorders.

Autism Res Treat 2014 16;2014:312163. Epub 2014 Sep 16.

School of Education, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

Autism spectrum disorder (ASD) is characterized by impairments in social communication deficits and the presence of restricted and repetitive behaviors, interests, or activities. Literature comparing the physical activity and fitness of children with ASD to typically developing peers is in need of attention. The purpose of this investigation was to examine the physical activity and fitness of school-aged children with ASD (N = 17) in comparison to typically developing peers (N = 12). Read More

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http://dx.doi.org/10.1155/2014/312163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182001PMC
October 2014
4 Reads

Mental health services for individuals with high functioning autism spectrum disorder.

Autism Res Treat 2014 3;2014:502420. Epub 2014 Sep 3.

Dual Diagnosis Service, Centre for Addiction and Mental Health, 501 Queen Street West, Toronto, ON, Canada M5V 2B4 ; Department of Psychiatry, University of Toronto, 250 College Street, 8th Floor, Toronto, ON, Canada M5T 1R8.

Adolescents and adults with an autism spectrum disorder (ASD) who do not have an intellectual impairment or disability (ID), described here as individuals with high-functioning autism spectrum disorder (HFASD), represent a complex and underserved psychiatric population. While there is an emerging literature on the mental health needs of children with ASD with normal intelligence, we know less about these issues in adults. Of the few studies of adolescents and adults with HFASD completed to date, findings suggest that they face a multitude of cooccurring psychiatric (e. Read More

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http://dx.doi.org/10.1155/2014/502420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168143PMC
October 2014
10 Reads

Tsc2 Haploinsufficiency Has Limited Effects on Fetal Brain Cytokine Levels during Gestational Immune Activation.

Authors:
Dan Ehninger

Autism Res Treat 2014 9;2014:761279. Epub 2014 Jul 9.

German Center for Neurodegenerative Diseases (DZNE), Ludwig-Erhard-Allee 2, 53175 Bonn, Germany.

Dysregulated TSC/mTOR signaling may play a pathogenetic role in forms of syndromic autism, such as autism associated with tuberous sclerosis, a genetic disorder caused by heterozygous TSC1 or TSC2 mutations. Environmental risk factors, such as gestational viral infections, may, in some cases, also contribute to the pathogenesis of autism and related neuropsychiatric disorders. We have recently found that a heterozygous Tsc2 mutation and the poly I:C model of maternal immune activation (MIA) interactively perturb fetal development and adult social behavior in mice, suggesting that these factors converge on shared pathways. Read More

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http://dx.doi.org/10.1155/2014/761279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119898PMC

Computer vision tools for low-cost and noninvasive measurement of autism-related behaviors in infants.

Autism Res Treat 2014 22;2014:935686. Epub 2014 Jun 22.

Department of Electrical and Computer Engineering, Department of Computer Science, and Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA.

The early detection of developmental disorders is key to child outcome, allowing interventions to be initiated which promote development and improve prognosis. Research on autism spectrum disorder (ASD) suggests that behavioral signs can be observed late in the first year of life. Many of these studies involve extensive frame-by-frame video observation and analysis of a child's natural behavior. Read More

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http://dx.doi.org/10.1155/2014/935686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090521PMC
July 2014
2 Reads

Defining autism: variability in state education agency definitions of and evaluations for autism spectrum disorders.

Autism Res Treat 2014 2;2014:327271. Epub 2014 Jun 2.

North Carolina State University, Raleigh, NC 27607, USA.

In light of the steady rise in the prevalence of students with autism, this study examined the definition of autism published by state education agencies (SEAs), as well as SEA-indicated evaluation procedures for determining student qualification for autism. We compared components of each SEA definition to aspects of autism from two authoritative sources: Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR) and Individuals with Disabilities Education Improvement Act (IDEA-2004). We also compared SEA-indicated evaluation procedures across SEAs to evaluation procedures noted in IDEA-2004. Read More

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http://dx.doi.org/10.1155/2014/327271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060325PMC

Parent training interventions for toddlers with autism spectrum disorder.

Autism Res Treat 2014 7;2014:839890. Epub 2014 May 7.

Université de Sherbrooke, Sherbrooke, QC, Canada J1H 5N4.

Background. Now that early identification of toddlers with autism spectrum disorder (ASD) is possible, efforts are being made to develop interventions for children under three years of age. Most studies on early intervention have focused on intensive and individual interventions. Read More

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http://dx.doi.org/10.1155/2014/839890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033505PMC
June 2014
2 Reads

Characteristics of children who lost the diagnosis of autism: a sample from istanbul, Turkey.

Autism Res Treat 2014 27;2014:472120. Epub 2014 Apr 27.

Private Education Center, 34140 Istanbul, Turkey.

Aim. The aim of this study was to describe a group of children who lost a diagnosis of autism following participation in early educational programs. Method. Read More

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http://dx.doi.org/10.1155/2014/472120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022169PMC
May 2014
1 Read

Recognition of emotion from facial expressions with direct or averted eye gaze and varying expression intensities in children with autism disorder and typically developing children.

Autism Res Treat 2014 3;2014:816137. Epub 2014 Apr 3.

Department of Psychology, DePaul University, 2219 N. Kenmore Avenue, Chicago, IL 60614, USA.

Eye gaze direction and expression intensity effects on emotion recognition in children with autism disorder and typically developing children were investigated. Children with autism disorder and typically developing children identified happy and angry expressions equally well. Children with autism disorder, however, were less accurate in identifying fear expressions across intensities and eye gaze directions. Read More

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http://dx.doi.org/10.1155/2014/816137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996291PMC
May 2014
3 Reads

Minor physical anomalies in adults with autism spectrum disorder and healthy controls.

Autism Res Treat 2014 24;2014:743482. Epub 2014 Mar 24.

Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.

Minor Physical Anomalies (MPAs) are subtle abnormalities of the head, face, and limbs, without significant cosmetic or functional impact to the individual. They are assumed to represent external markers of developmental deviations during foetal life. MPAs have been suggested to indicate severity in mental illness and constitute external markers for atypical brain development. Read More

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http://dx.doi.org/10.1155/2014/743482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982266PMC
April 2014
2 Reads

Conceptualisation and development of a quality of life measure for parents of children with autism spectrum disorder.

Autism Res Treat 2014 20;2014:160783. Epub 2014 Mar 20.

University of New South Wales, Sydney, NSW 2052, Australia.

Parents of children with autism spectrum disorder (ASD) tend to experience greater psychological distress than parents of typically developing children or children with other disabilities. Quality of Life (QoL) is increasingly recognised as a critical outcome measure for planning and treatment purposes in ASD. There is a need for ASD-specific QoL measures as generic measures may not capture all relevant aspects of living with ASD. Read More

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http://dx.doi.org/10.1155/2014/160783DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977417PMC
April 2014
3 Reads

Potential Role of Selenoenzymes and Antioxidant Metabolism in relation to Autism Etiology and Pathology.

Autism Res Treat 2014 5;2014:164938. Epub 2014 Mar 5.

Energy & Environmental Research Center, University of North Dakota, 15 North 23rd Street, Stop 9018, Grand Forks, ND 58202, USA.

Autism and autism spectrum disorders (ASDs) are behaviorally defined, but the biochemical pathogenesis of the underlying disease process remains uncharacterized. Studies indicate that antioxidant status is diminished in autistic subjects, suggesting its pathology is associated with augmented production of oxidative species and/or compromised antioxidant metabolism. This suggests ASD may result from defects in the metabolism of cellular antioxidants which maintain intracellular redox status by quenching reactive oxygen species (ROS). Read More

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http://dx.doi.org/10.1155/2014/164938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966422PMC
June 2014
4 Reads