405 results match your criteria Australian prescriber[Journal]


Managing acute dental pain without codeine.

Authors:
Leanne Teoh

Aust Prescr 2020 Apr 1;43(2):64. Epub 2020 Apr 1.

Bundoora Dental Clinic, Melbourne.

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http://dx.doi.org/10.18773/austprescr.2020.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186268PMC

Teduglutide for short bowel syndrome.

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Aust Prescr 2020 Apr 3;43(2):72-73. Epub 2020 Mar 3.

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http://dx.doi.org/10.18773/austprescr.2020.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186272PMC

Risankizumab for psoriasis.

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Aust Prescr 2020 Apr 20;43(2):70-71. Epub 2020 Feb 20.

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http://dx.doi.org/10.18773/austprescr.2020.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186275PMC

Fremanezumab for migraine.

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Aust Prescr 2020 Apr 3;43(2):68-69. Epub 2020 Mar 3.

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http://dx.doi.org/10.18773/austprescr.2020.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186266PMC

Estimating renal function for patients in wheelchairs.

Aust Prescr 2020 Apr 1;43(2):67. Epub 2020 Apr 1.

Department of Clinical Pharmacology and Toxicology, St Vincent's Hospital, Sydney.

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http://dx.doi.org/10.18773/austprescr.2020.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186273PMC

Errors in electronic prescribing systems.

Aust Prescr 2020 Apr 1;43(2):66. Epub 2020 Apr 1.

Centre for Health Systems and Safety Research, Australian Institute of Health Innovation, Macquarie University, Sydney.

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http://dx.doi.org/10.18773/austprescr.2020.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186278PMC

Atrial fibrillation - QT interval and catheter ablation.

Aust Prescr 2020 Apr 1;43(2):65. Epub 2020 Apr 1.

Cardiac Electrophysiology Unit, Department of Cardiology, Canberra Hospital and Health Services, Australian National University.

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http://dx.doi.org/10.18773/austprescr.2020.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186267PMC

Prescribing in renal supportive care.

Authors:
Kelly Li Mark Brown

Aust Prescr 2020 Apr 1;43(2):57-60. Epub 2020 Apr 1.

Renal Medicine, St George Hospital, Sydney.

Renal Supportive Care Incorporates The Principles Of Palliative Care Into The Management Of Patients With Advanced Kidney Disease Its Focus Is On Improving The Quality Of Life For Patients With A High Burden Of Symptoms:

Common Problems Include Pain Restless Legs Syndrome And Uraemic Pruritus Symptom Management Must Involve Patient Participation Education And Non-pharmacological Strategies To Address Both Physical And Psychosocial Problems And To Prioritise Patient-centred Goals:

The Patients Are Medically Complex And Polypharmacy Is Common When Prescribing It Is Important To Consider The Altered Pharmacokinetics Potential Drug Interactions And The Clearance Of Drugs By Dialysis: Read More

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http://dx.doi.org/10.18773/austprescr.2020.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186271PMC

Antiemetic drugs: what to prescribe and when.

Aust Prescr 2020 Apr 1;43(2):49-56. Epub 2020 Apr 1.

Drug Health Services and Clinical Pharmacology and Toxicology, Royal Prince Alfred Hospital, Sydney.

Nausea And Vomiting Are Common Symptoms With Many Possible Causes Including The Adverse Effects Of Drugs If A Drug Is Indicated The Cause Guides The Choice Of Antiemetic Drug:

The Main Antiemetic Classes Include Antagonists Of The Serotonin Dopamine Histamine Muscarinic And Neurokinin Systems Corticosteroids And Benzodiazepines Some Antiemetics Appear More Effective For Specific Indications:

Serotonin And Neurokinin Antagonists Such As Ondansetron And Aprepitant Are Highly Effective In Treating Chemotherapy-induced Nausea And Vomiting Metoclopramide And Antihistamines Are First-line Options For Nausea And Vomiting In Pregnancy:

Serotonin Antagonists And Some Dopamine Antagonists Such As Metoclopramide Can Prolong The Qt Interval On The Ecg Dopamine Antagonists Can Cause Extrapyramidal Adverse Effects Particularly In Children: Read More

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http://dx.doi.org/10.18773/austprescr.2020.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186277PMC

Oral or intravenous antibiotics?

Aust Prescr 2020 Apr 1;43(2):45-48. Epub 2020 Apr 1.

Royal Brisbane and Women's Hospital, Brisbane.

Intravenous Antibiotics Are Overused In Hospitals Many Infections Can Be Managed With Oral Antibiotics:

Oral Antibiotics Avoid The Adverse Effects Of Intravenous Administration They Are Also Usually Less Expensive:

When Intravenous Antibiotics Are Indicated It May Be Possible To Switch To Oral Therapy After A Short Course There Are Guidelines To Aid The Clinician With The Timing Of The Switch So That There Is No Loss Of Efficacy:

Infections That May Be Suitable For A Short Course Of Intravenous Antibiotic Include Pneumonia Complicated Urinary Tract Infections Certain Intra-abdominal Infections Gram-negative Bacteraemia Acute Exacerbations Of Chronic Lung Disease And Skin And Soft Tissue Infections:

Bone And Joint Infections And Infective Endocarditis Are Managed With Prolonged Courses Of Intravenous Antibiotics However There Is Research Looking At The Feasibility Of An Earlier Switch To Oral Antibiotics In These Conditions: Read More

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http://dx.doi.org/10.18773/austprescr.2020.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186270PMC

Management of dental pain in primary care.

Aust Prescr 2020 Apr 1;43(2):39-44. Epub 2020 Apr 1.

Melbourne Dental School, University of Melbourne.

Patients Sometimes Present To A Medical Practitioner With Dental Pain If They Cannot See A Dentist:

Doctors Need To Be Aware Of The Common Dental Diseases That Result In Pain So They Can Help To Manage The Patient’s Symptoms Until They Are Able To See A Dentist:

Appropriate Advice Regarding Analgesics For Dental Pain Is Important Paracetamol And Ibuprofen Are More Effective In Combination Than Either Of Them Alone With Or Without Opioids:

Antibiotics Are Only Indicated As An Adjunct To Dental Treatment When There Are Signs Of Systemic Involvement Progressive And Rapid Spread Of Infection Or When The Patient Is Immunocompromised: Read More

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http://dx.doi.org/10.18773/austprescr.2020.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186276PMC

Faecal microbiota transplantation: indications, evidence and safety.

Aust Prescr 2020 Apr 1;43(2):36-38. Epub 2020 Apr 1.

Inflammatory Bowel Disease Service, Department of Gastroenterology, Queen Elizabeth Hospital, Adelaide.

The Human Gut Contains Many Species Of Microorganisms Many Of Which Have A Role In Maintaining Good Health The Gut Microbiota Can Be Affected By Diet Diseases And Drugs Especially Antibiotics:

Faecal Microbiota Transplantation Involves Transplanting Faecal Material From A Healthy Person To A Patient With The Aim Of Treating Disease It Is A Recommended Treatment Option For Patients With Recurrent Or Refractory Clostridioides Difficile As It Has A Cure Rate Over 90%:

There Is Evidence That Faecal Microbiota Transplantation Can Induce Remission In Ulcerative Colitis However Maintenance Of Remission Data Are Lacking For Other Diseases It Currently Should Not Be Used Outside A Clinical Trial:

Stool Donors Have To Be Healthy And Are Screened For A Range Of Diseases As Faecal Material Is Usually Transplanted During Colonoscopy The Recipient Must Have Bowel Preparation Before The Procedure:

Adverse Effects Are Mainly Gastrointestinal And Usually Resolve In The Week Following Transplantation There Are Limited Data On Long-term Safety: Read More

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http://dx.doi.org/10.18773/austprescr.2020.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186269PMC

Erratum: Blood pressure: at what level is treatment worthwhile? [Correction].

Authors:

Aust Prescr 2020 02 19;43(1):33. Epub 2019 Dec 19.

[This corrects the article DOI: 10.18773/austprescr.2019. Read More

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http://dx.doi.org/10.18773/austprescr.2019.078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026921PMC
February 2020

Bruce Shepherd Medal for independent medicine.

Authors:

Aust Prescr 2020 Feb 3;43(1):32. Epub 2020 Feb 3.

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http://dx.doi.org/10.18773/austprescr.2020.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026920PMC
February 2020

Tisagenlecleucel for B-cell cancers.

Authors:

Aust Prescr 2020 Feb 17;43(1):30-31. Epub 2019 Dec 17.

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http://dx.doi.org/10.18773/austprescr.2019.077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026923PMC
February 2020

Patiromer sorbitex calcium for hyperkalaemia.

Authors:

Aust Prescr 2020 Feb 17;43(1):28-29. Epub 2019 Dec 17.

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http://dx.doi.org/10.18773/austprescr.2019.076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026922PMC
February 2020

National Medicines Policy 2.0: a vision for the future.

Aust Prescr 2020 Feb 3;43(1):24-26. Epub 2020 Feb 3.

Sydney Pharmacy School, Faculty of Medicine and Health, The University of Sydney.

Australia’s National Medicines Policy Was Launched 20 Years Ago With The Aim Of Improving Health Outcomes For All Australians It Was Developed In Partnership With Healthcare Professionals Consumers And The Pharmaceutical Industry:

The Key Parts Of The Policy Focus On Timely Access To High-quality And Affordable Medicines And Their Safe And Judicious Use It Also Supports A Viable And Responsible Pharmaceutical Industry:

Since The Policy Was First Launched Australia Has Seen Significant Changes In Healthcare Systems Medicines Subsidies Health Services Remuneration Digital Technologies And The Pharmaceutical Industry:

Medicines Themselves Have Also Changed As Have Consumers’ Expectations To Respond To These Changes The National Medicines Policy Needs To Be Updated With A Greater Focus On Implementing And Measuring Outcomes: Read More

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http://dx.doi.org/10.18773/austprescr.2020.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026915PMC
February 2020

Drug interaction resources: mind the gaps.

Authors:
Louise Grannell

Aust Prescr 2020 Feb 3;43(1):18-23. Epub 2020 Feb 3.

Alfred Health, Melbourne.

Drug Interactions Can Lead To Significant Toxicity Or Loss Of Clinical Effect The Risks Increase With The Number Of Drugs The Patient Takes:

General And Specialised Drug Interaction Resources Are Available Access To Up-to-date Electronic Resources Is Encouraged:

There Are Gaps In The Information On Interactions For New Drugs Those With Complicated Metabolism And Drugs With Limited Use It May Be Necessary To Use Multiple Resources To Find The Information:

When Assessing Information About Interactions Clinicians Should Evaluate The Relevance For Each Patient In High-risk Situations Expert Advice Can Be Valuable:

Clinicians Should Report New Or Unusual Drug Interactions To The Therapeutic Goods Administration: Read More

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http://dx.doi.org/10.18773/austprescr.2020.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026916PMC
February 2020

Management of heart failure with preserved ejection fraction.

Aust Prescr 2020 Feb 3;43(1):12-17. Epub 2020 Feb 3.

Monash University, Clayton, Vic.

Heart Failure With Preserved Ejection Fraction Is A Highly Heterogenous Disease There Is Emerging Evidence That Treatment Should Be Tailored To The Individual’s Associated Comorbidities:

No Current Algorithms Exist For The Management Of Heart Failure With Preserved Ejection Fraction Conventional Therapies Used In Heart Failure With Reduced Ejection Fraction Are Yet To Show A Mortality Benefit:

Key Treatment Objectives Include Control Of Hypertension And Fluid Balance:

Common Comorbidities Include Coronary Artery Disease Atrial Fibrillation Obesity Diabetes Renal Impairment And Pulmonary Hypertension These Comorbidities Should Be Considered In All Patients And Treatment Optimised: Read More

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http://dx.doi.org/10.18773/austprescr.2020.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026917PMC
February 2020

Managing the overlap of asthma and chronic obstructive pulmonary disease.

Authors:
Anne Knight

Aust Prescr 2020 Feb 3;43(1):7-11. Epub 2020 Feb 3.

Hunter New England Local Health District, Taree, NSW.

Approximately 20% Of Patients With Obstructive Lung Disease Have Features Of Both Asthma And Chronic Obstructive Pulmonary Disease:

These Patients Have A Higher Burden Of Disease And Increased Exacerbations Compared To Those With Asthma Or Chronic Obstructive Pulmonary Disease Alone:

Management Should Address Dominant Clinical Features In Each Individual Patient And Comorbidities Should Be Considered:

There Are Several Interventions That Are Useful In The Management Of Both Asthma And Chronic Obstructive Pulmonary Disease:

As Inhaled Corticosteroids Are Key To The Management Of Asthma They Are Recommended In Patients With Overlapping Chronic Obstructive Pulmonary Disease: Read More

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http://dx.doi.org/10.18773/austprescr.2020.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026918PMC
February 2020

Herpes zoster vaccination in Australia: what's available and who benefits?

Aust Prescr 2020 Feb 3;43(1):2-6. Epub 2020 Feb 3.

National Centre for Immunisation Research and Surveillance, Kids Research, The Children's Hospital at Westmead, Sydney.

Acute Herpes Zoster And Associated Postherpetic Neuralgia Is Caused By Reactivation Of Latent Varicella Zoster Virus It Can Be Debilitating For Older Adults And Interfere With Activities Of Daily Living:

A Live Attenuated Single-dose Vaccine That Protects Against Both Acute Herpes Zoster And Postherpetic Neuralgia Is Available For Free To All Australians Aged 70 Years And In A Catch-up Program For Those Aged 71–79 Years:

The Vaccine Is Contraindicated In People Who Are Immunocompromised But Can Be Considered In Those Who Are Receiving Low Doses Of Selected Disease-modifying Antirheumatic Drugs:

Records Of The Australian Immunisation Register Suggest That Only A Third Of 70 Year Olds Received The Vaccine In The First Year-and-a-half Of The Program This Is Likely An Underestimation But Emphasises The Importance Of Ensuring The Vaccine Is Offered To All Eligible Patients And That Vaccination Is Recorded On The Register:

A Non-live Recombinant Herpes Zoster Vaccine Has Recently Been Developed Which Is More Efficacious Than The Live Vaccine In Clinical Trials It Is Registered In Australia But Not Currently Available: Read More

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http://dx.doi.org/10.18773/austprescr.2020.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026919PMC
February 2020

Antipsychotic switching tool [Update].

Authors:

Aust Prescr 2019 Dec 29;42(6):213. Epub 2019 Oct 29.

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http://dx.doi.org/10.18773/austprescr.2019.072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954871PMC
December 2019

Crisaborole for atopic dermatitis.

Authors:

Aust Prescr 2019 Dec 2;42(6):211. Epub 2019 Dec 2.

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http://dx.doi.org/10.18773/austprescr.2019.075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954874PMC
December 2019

Neratinib for breast cancer.

Authors:

Aust Prescr 2019 Dec 21;42(6):209-210. Epub 2019 Nov 21.

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http://dx.doi.org/10.18773/austprescr.2019.074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954866PMC
December 2019

Dupilumab for atopic dermatitis.

Authors:

Aust Prescr 2019 Dec 10;42(6):207-208. Epub 2019 Oct 10.

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http://dx.doi.org/10.18773/austprescr.2019.071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954865PMC
December 2019

Top 10 drugs 2018-19.

Authors:

Aust Prescr 2019 Dec 2;42(6):204. Epub 2019 Dec 2.

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http://dx.doi.org/10.18773/austprescr.2019.073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954868PMC
December 2019

The 2018 Aged Care National Antimicrobial Prescribing Survey: results show room for improvement.

Aust Prescr 2019 Dec 14;42(6):200-203. Epub 2019 Nov 14.

National Centre for Antimicrobial Stewardship, Melbourne, Vic.

The Annual Aged Care National Antimicrobial Prescribing Survey Aims To Identify Local And National Prescribing Issues And Guide Antimicrobial Stewardship Goals:

In The 2018 Point Prevalence Survey Medication Charts Of Over 20000 Residents Were Reviewed From 407 Participating Facilities Across Australia:

On The Day Of The Survey Almost 10% Of Residents Were Prescribed An Antimicrobial:

Nearly Two-thirds Of Recently Prescribed Antimicrobials Were For Residents Who Had No Documented Signs Or Symptoms Of Infection:

Over A Quarter Of Antimicrobials Had Been Prescribed For Longer Than Six Months:

Incomplete Documentation Was A Prominent Barrier To Proper Review Of Antimicrobial Therapy With The Indication Review Date Or Stop Date Not Documented For Many Prescriptions:

Recommendations Include Using Appropriate Microbiological Testing To Guide Prescribing Following National Antimicrobial Prescribing Guidelines Documenting The Indication For The Antimicrobial And Its Start Stop And Review Dates And Monitoring And Re-evaluating Long-term Antimicrobial Use: Read More

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http://dx.doi.org/10.18773/austprescr.2019.066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954873PMC
December 2019

Penicillin allergy: a practical approach to assessment and prescribing.

Aust Prescr 2019 Dec 2;42(6):192-199. Epub 2019 Dec 2.

Antimicrobial Stewardship, Drug and Antibiotic Allergy Service and Centre for Antibiotic Allergy and Research, Austin Health, Melbourne.

Penicillin Allergies Are Not Always Lifelong Approximately 50% Are Lost Over Five Years:

A Reaction To Penicillin During A Childhood Infection Is Unlikely To Be A True Allergy:

Only 1–2% Of Patients With A Confirmed Penicillin Allergy Have An Allergy To Cephalosporins In Patients With A Low Risk Of Severe Allergic Reactions Cephalosporins Are A Relatively Safe Treatment Option:

Patients With A History Of Delayed Non-severe Reactions Such As Mild Childhood Rashes That Occurred Over 10 Years Ago May Be Suitable For An Oral Rechallenge With Low-dose Penicillin This Should Be Done In A Supervised Hospital Environment:

In Many Cases With Appropriate Assessment And Allergy Testing It May Be Possible To Remove The Penicillin Allergy Label: Read More

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http://dx.doi.org/10.18773/austprescr.2019.065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954877PMC
December 2019

Atrial fibrillation: an update on management.

Aust Prescr 2019 Dec 2;42(6):186-191. Epub 2019 Dec 2.

Cardiac Electrophysiology Unit, Department of Cardiology, Canberra Hospital and Health Services, Australian National University.

Atrial Fibrillation Carries A Markedly Increased Risk Of Stroke And Left Ventricular Dysfunction And Is Associated With Reduced Quality Of Life:

In Light Of The Potential For Poor Outcomes And The Likely Understated Presence Of Silent Atrial Fibrillation Opportunistic Screening Should Be Carried Out In General Practice:

Modifying The Risk Factors For Atrial Fibrillation Is The Cornerstone Of Management With Adjuvant Drug Therapy To Help Maintain Sinus Rhythm Control The Ventricular Rate And Reduce The Risk Of Cerebral Thromboembolism:

The Need For Anticoagulant Therapy Can Be Assessed By Using The Revised Cha2ds2-vasc Score Direct Oral Anticoagulants Are Now Preferred To Warfarin In Those Who Qualify For Their Use:

Catheter Ablation Is An Effective Option To Improve Survival In Patients With Left Ventricular Dysfunction It Also Improves Quality Of Life And Reduces Arrhythmia-related Hospital Admissions: Read More

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http://dx.doi.org/10.18773/austprescr.2019.067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954870PMC
December 2019

Psychoactive drugs and driving.

Authors:
Vanita Parekh

Aust Prescr 2019 Dec 2;42(6):182-185. Epub 2019 Dec 2.

Clinical Forensic Medical Services, Canberra Hospital, ACT.

Any Drug Or Substance With Effects On The Central Nervous System Can Impair The Ability To Drive Safely:

When Prescribing Consider The Effects Of Each Drug On Driving As Well As The Use Of Other Substances Advise The Patient Of The Risks:

Opioids Benzodiazepines Anticonvulsants Antipsychotics And Sedating Antidepressants Increase The Risk Of Crashing Erratic Use Of Sedatives Causes A Higher Level Of Impairment Than Stable Regimens:

Patients Who Have Complex Medical Conditions And Take Multiple Drugs Should Undergo A Fitness-to-drive Assessment: Read More

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http://dx.doi.org/10.18773/austprescr.2019.070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954869PMC
December 2019

When should treatment be started for hypertension?

Authors:

Aust Prescr 2019 Dec 2;42(6):180-181. Epub 2019 Dec 2.

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http://dx.doi.org/10.18773/austprescr.2019.069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954872PMC
December 2019

Medicines information: dwindling support in the age of information overload.

Authors:
Felicity Prior

Aust Prescr 2019 Dec 2;42(6):178-179. Epub 2019 Dec 2.

Hunter Drug Information Service, Calvary Mater Newcastle, Waratah, New South Wales.

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http://dx.doi.org/10.18773/austprescr.2019.068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954876PMC
December 2019

Erratum: Blood pressure: at what level is treatment worthwhile? [Correction].

Authors:

Aust Prescr 2019 Oct 1;42(5):175. Epub 2019 Oct 1.

[This corrects the article DOI: 10.18773/austprescr.2019. Read More

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http://dx.doi.org/10.18773/austprescr.2019.062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787306PMC
October 2019

Tezacaftor/ivacaftor for cystic fibrosis.

Authors:

Aust Prescr 2019 Oct 13;42(5):174-175. Epub 2019 Sep 13.

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http://dx.doi.org/10.18773/austprescr.2019.060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787300PMC
October 2019
1 Read

Plitidepsin for multiple myeloma.

Authors:

Aust Prescr 2019 Oct 13;42(5):172-173. Epub 2019 Sep 13.

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http://dx.doi.org/10.18773/austprescr.2019.059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787298PMC
October 2019

Lumacaftor/ivacaftor for cystic fibrosis.

Authors:

Aust Prescr 2019 Oct 13;42(5):170-171. Epub 2019 Sep 13.

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http://dx.doi.org/10.18773/austprescr.2019.058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787305PMC
October 2019

Binimetinib plus encorafenib for metastatic melanoma.

Authors:

Aust Prescr 2019 Oct 13;42(5):168. Epub 2019 Sep 13.

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http://dx.doi.org/10.18773/austprescr.2019.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787304PMC
October 2019

How to adjust drug doses in chronic kidney disease.

Aust Prescr 2019 Oct 1;42(5):163-167. Epub 2019 Oct 1.

Department of Clinical Pharmacology and Toxicology, St Vincent's Hospital, Sydney.

Drugs Excreted By The Kidney Require Dose Reduction In Chronic Kidney Disease This Adjustment Depends On The Severity Of The Disease And What Proportion Of The Drug Is Eliminated By The Kidneys:

The Estimated Glomerular Filtration Rate Can Generally Be Used To Guide Dose Adjustment In Patients With Stable Kidney Function However The Formula Can Be Misleading In Some Patient Subsets And Other Approaches Are Required:

At Extremes Of Body Mass The Estimated Glomerular Filtration Rate Can Under- Or Overestimate Kidney Function It May Need To Be Adjusted For Body Surface Area Particularly For Drugs With A Narrow Therapeutic Range Or Requiring A Minimum Concentration To Be Effective Close Monitoring Of Drug Effect And Toxicity Is Also Needed And Can Be Supported By Therapeutic Drug Monitoring:

For Short Courses Of Drugs With A Wide Therapeutic Index Dose Adjustment May Not Be Needed:

Alternative Methods For Quantifying Kidney Function Include The Cockcroft-gault Formula Estimates Creatinine Clearance Or Direct Measures Of Glomerular Filtration Rate Using Exogenous Isotope Compounds These Are Not Commonly Required: Read More

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http://dx.doi.org/10.18773/austprescr.2019.054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787303PMC
October 2019

Amiodarone in the aged.

Aust Prescr 2019 Oct 1;42(5):158-162. Epub 2019 Oct 1.

Royal North Shore Hospital.

Amiodarone Is A Highly Effective Antiarrhythmic Drug But Can Have Serious Adverse Effects Particularly In Older Patients If Possible It Should Not Be Used Purely For Controlling The Heart Rate:

If A Prescription For Amiodarone Is Contemplated Particularly For An Older Patient Consult A Cardiologist Avoid Amiodarone In Patients With Significant Conduction System Disease Significant Liver Or Pulmonary Disease Or Hyperthyroidism:

Regular Monitoring Of The Patient Clinically And Biochemically Is Required To Identify Complications At An Early Treatable Stage Maintain A High Level Of Suspicion If A Patient Taking Amiodarone Is Experiencing Adverse Reactions And Presents With New Symptoms:

Consider Potential Drug Interactions When Other Drugs Are Prescribed With Amiodarone The Effects And Toxicities Of Amiodarone May Persist Weeks After It Is Stopped: Read More

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http://dx.doi.org/10.18773/austprescr.2019.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787299PMC
October 2019

Antipsychotic switching tool.

Aust Prescr 2019 Oct 1;42(5):156. Epub 2019 Oct 1.

Delmont Private Hospital, Glen Iris, Victoria.

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http://dx.doi.org/10.18773/austprescr.2019.056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787302PMC
October 2019

Stopping and switching antipsychotic drugs.

Aust Prescr 2019 Oct 1;42(5):152-157. Epub 2019 Oct 1.

Centre for Mental Health Education and Research, Delmont Private Hospital, Glen Iris, Victoria.

In General Specialist Advice Should Be Sought When Stopping Or Switching Antipsychotics:

While Antipsychotics Are Often Needed Long Term There Are Circumstances When Clinicians Patients And Families Should Reconsider The Benefits Versus The Harms Of Continuing Treatment:

Withdrawal Syndromes Relapse And Rebound Can Occur If Antipsychotics Are Discontinued Especially If They Are Stopped Abruptly Generally They Should Be Reduced And Stopped Slowly Ideally Over Weeks To Months:

Relapse Of Psychosis And Exacerbation Occur In Most Patients With Psychotic Disorders Occasionally With Drastic Consequences Sometimes This Occurs Many Months After Stopping Antipsychotics:

Switching From One Antipsychotic To Another Is Frequently Indicated Due To An Inadequate Treatment Response Or Unacceptable Adverse Effects It Should Be Carried Out Cautiously And Under Close Observation: Read More

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http://dx.doi.org/10.18773/austprescr.2019.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787301PMC
October 2019
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The Prescribing Skills Assessment: a step towards safer prescribing.

Aust Prescr 2019 Oct 1;42(5):148-150. Epub 2019 Oct 1.

Humphries Road Medical Centre, Frankston South, Victoria.

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http://dx.doi.org/10.18773/austprescr.2019.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787296PMC
October 2019

Erratum: Prescribing for transgender patients [Correction].

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Aust Prescr 2019 Aug 4;42(4):145. Epub 2019 Jul 4.

[This corrects the article DOI: 10.18773/austprescr.2019. Read More

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http://dx.doi.org/10.18773/austprescr.2019.053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698243PMC

Peramivir for influenza.

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Aust Prescr 2019 Aug 17;42(4):143. Epub 2019 Jun 17.

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http://dx.doi.org/10.18773/austprescr.2019.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698233PMC

Inotuzumab ozogamicin for acute lymphoblastic leukaemia.

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Aust Prescr 2019 Aug 17;42(4):141-142. Epub 2019 Jun 17.

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http://dx.doi.org/10.18773/austprescr.2019.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698239PMC

Iatrogenic Cushing's syndrome with inhaled fluticasone.

Aust Prescr 2019 Aug 1;42(4):139-140. Epub 2019 Aug 1.

Royal North Shore Hospital, Sydney.

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http://dx.doi.org/10.18773/austprescr.2019.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698236PMC

The safety of computerised prescribing in hospitals.

Aust Prescr 2019 Aug 1;42(4):136-138. Epub 2019 Aug 1.

Faculty of Health Sciences, The University of Sydney.

The Implementation Of Computerised Prescribing Can Result In Large Reductions In Prescribing Error Rates The Flow-on Effects To Patient Outcomes Are Not Well Studied:

The Reduction In Errors Is Dependent On Prescribers Becoming Proficient In Using The Electronic Prescribing System All Potential Safety Benefits Are Therefore Not Expected To Be Achieved Immediately:

Electronic Prescribing Systems Introduce New Types Of Errors Most Frequently Errors In Selection Some Of These Errors Can Be Prevented If The System Is Well Designed:

Computerised Decision Support Embedded In Electronic Prescribing Systems Has Enormous Potential To Improve Medication Safety However Current Support Systems Have A Limited Capacity To Provide Context-relevant Advice To Prescribers: Read More

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http://dx.doi.org/10.18773/austprescr.2019.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698235PMC

Meningococcal vaccines in Australia: a 2019 update.

Aust Prescr 2019 Aug 1;42(4):131-135. Epub 2019 Aug 1.

National Centre for Immunisation Research and Surveillance for Vaccine Preventable Diseases, The Children's Hospital at Westmead, Sydney.

Invasive Meningococcal Disease Is A Rare But Serious Infection Caused By Neisseria Meningitidis:

Serogroup B Was The Predominant Serogroup Causing Invasive Meningococcal Disease In Australia Until 2015 Serogroup W Disease Has Increased Substantially Since 2014 And In 2017 Serogroups B And W Caused Similar Numbers Of Invasive Disease Cases:

Vaccines Against Serogroups A C W Y And B Are Available For Anyone Who Wishes To Reduce The Risk Of Meningococcal Disease:

Vaccination Is Strongly Recommended For People In High-risk Age Or Population Groups These Are Children Under 2 Years 15–19 Year Olds Aboriginal And Torres Strait Islander Children And People With Medical Occupational Behavioural Or Travel-related Risk Factors For Invasive Meningococcal Disease:

Meningococcal Acwy Vaccine Is Funded Under The National Immunisation Program For Babies Aged 12 Months Since April 2019 It Has Been Funded For Year 10 Students Through A School Program There Are Additional State And Territory-based Programs For Both Meningococcal Acwy And Meningococcal B Vaccines: Read More

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http://dx.doi.org/10.18773/austprescr.2019.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698237PMC
August 2019
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