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    5786 results match your criteria Australian and New Zealand Journal of Psychiatry[Journal]

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    Lower antioxidant capacity in the prefrontal cortex of individuals with schizophrenia.
    Aust N Z J Psychiatry 2017 Sep 1:4867417728805. Epub 2017 Sep 1.
    1 Schizophrenia Research Institute, Sydney, NSW, Australia.
    Objective: The glutathione (GSH) pathway is the main antioxidant system to protect against oxidative stress in the human brain. In this study, we tested whether molecular components of the GSH antioxidant system are changed in dorsolateral prefrontal cortex tissue from people with schizophrenia compared to controls.

    Method: The levels of total glutathione and reduced GSH were determined by fluorometric assay via quantifying thiols in extracts from frontal cortex of 68 people. Read More

    Treating body, treating mind: The experiences of people with psychotic disorders and their general practitioners - Findings from the Australian National Survey of High Impact Psychosis.
    Aust N Z J Psychiatry 2017 Sep 1:4867417728806. Epub 2017 Sep 1.
    1 Neuropsychiatric Epidemiology Research Unit, Division of Psychiatry, School of Medicine, University of Western Australia, Perth, WA, Australia.
    Objectives: To describe from the perspective of people living with psychotic illness their use of general practitioner services over a 12-month period and the experiences, attitudes and challenges general practitioners face providing health care to this population.

    Methods: A two-phase design was used. Phase 1, screening for psychosis, occurred in public specialised mental health services and non-government organisations within seven catchment sites across Australia. Read More

    Borderline personality disorder and polycystic ovary syndrome: A review of the literature.
    Aust N Z J Psychiatry 2017 Sep 1:4867417730650. Epub 2017 Sep 1.
    1 Monash Alfred Psychiatry Research Centre (MAPrc), Melbourne, VIC, Australia.
    Objective: This review examines the existing evidence for the relationship between borderline personality disorder and polycystic ovary syndrome, and to identify commonalities in etiological mechanisms of borderline personality disorder and polycystic ovary syndrome that might explain the relationship between these seemingly disparate disorders.

    Methods: A search of Medline, EMBASE and Cochrane Central was undertaken on 5 December 2016 to identify studies investigating women with borderline personality disorder and polycystic ovary syndrome (or symptoms and markers specific to polycystic ovary syndrome).

    Results: Nine studies were identified, including three cross-sectional studies investigating symptoms of polycystic ovary syndrome in women with borderline personality disorder, two cross-sectional and one cohort study examining the prevalence of psychiatric diagnoses in women with polycystic ovary syndrome and three case reports of comorbid borderline personality disorder and polycystic ovary syndrome. Read More

    An appraisal of practice guidelines for smoking cessation in people with severe mental illness.
    Aust N Z J Psychiatry 2017 Aug 1:4867417726176. Epub 2017 Aug 1.
    1 School of Public Health, The University of Queensland, Herston, QLD, Australia.
    Objective: To review the quality of current smoking cessation guidelines that include recommendations for people with severe mental illness.

    Methods: A systematic search of scientific databases, central government health authority websites, psychiatry peak bodies, guideline clearing houses and Google was undertaken for relevant smoking cessation guidelines. Three reviewers independently assessed guideline quality using the AGREE II (Appraisal of Guidelines for REsearch and Evaluation II) instrument. Read More

    Getting RID of the blues: Formulating a Risk Index for Depression (RID) using structural equation modeling.
    Aust N Z J Psychiatry 2017 Aug 1:4867417726860. Epub 2017 Aug 1.
    2 Department of Statistics, Data Science and Epidemiology, Swinburne University of Technology, Melbourne, VIC, Australia.
    Objective: While risk factors for depression are increasingly known, there is no widely utilised depression risk index. Our objective was to develop a method for a flexible, modular, Risk Index for Depression using structural equation models of key determinants identified from previous published research that blended machine-learning with traditional statistical techniques.

    Methods: Demographic, clinical and laboratory variables from the National Health and Nutrition Examination Study (2009-2010, N = 5546) were utilised. Read More

    A framework to create more mentally healthy workplaces: A viewpoint.
    Aust N Z J Psychiatry 2017 Aug 1:4867417726174. Epub 2017 Aug 1.
    1 School of Psychiatry, University of New South Wales, Sydney, NSW, Australia.
    Mental illness is now the leading cause of long-term sickness absence among Australian workers, with significant costs to the individual, their employers and society more broadly. However, to date, there has been little evidence-informed guidance as to what workplaces should be doing to enhance their employees' mental health and wellbeing. In this article, we present a framework outlining the key strategies employers can implement to create more mentally healthy workplaces. Read More

    ICD-11 and DSM-5 personality trait domains capture categorical personality disorders: Finding a common ground.
    Aust N Z J Psychiatry 2017 Aug 1:4867417727867. Epub 2017 Aug 1.
    4 Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
    Objective: The five personality disorder trait domains in the proposed International Classification of Diseases, 11th edition and the Diagnostic and Statistical Manual of Mental Disorders, 5th edition are comparable in terms of Negative Affectivity, Detachment, Antagonism/Dissociality and Disinhibition. However, the International Classification of Diseases, 11th edition model includes a separate domain of Anankastia, whereas the Diagnostic and Statistical Manual of Mental Disorders, 5th edition model includes an additional domain of Psychoticism. This study examined associations of International Classification of Diseases, 11th edition and Diagnostic and Statistical Manual of Mental Disorders, 5th edition trait domains, simultaneously, with categorical personality disorders. Read More

    Translational delivery of Cool Little Kids to prevent child internalising problems: Randomised controlled trial.
    Aust N Z J Psychiatry 2017 Aug 1:4867417726582. Epub 2017 Aug 1.
    9 Centre for Emotional Health, Macquarie University, Sydney, NSW, Australia.
    Objective: To determine whether a population-delivered parenting programme assists in preventing internalising problems at school entry for preschool children at-risk with temperamental inhibition.

    Methods: Design: a randomised controlled trial was used.

    Setting: the setting was 307 preschool services across eight socioeconomically diverse government areas in Melbourne, Australia. Read More

    Prospective associations between personality and bullying among Australian adolescents.
    Aust N Z J Psychiatry 2017 Aug 1:4867417726583. Epub 2017 Aug 1.
    NHMRC Centre for Research Excellence in Mental Health and Substance Use, National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW, Australia.
    Objective: This study aimed to examine whether high-risk personality dimensions increased susceptibility to bullying victimisation and perpetration among Australian adolescents.

    Method: Longitudinal cohort study of 527 secondary school students in Australia (baseline average age = 13 years, 67% female and 93% Australian-born). Bullying was measured using an amended version of the Revised Olweus Bully/Victim Scale. Read More

    Effectiveness of a treatment guideline for schizophrenia in adolescents: Lessons from a middle-income country.
    Aust N Z J Psychiatry 2017 Aug 1:4867417726581. Epub 2017 Aug 1.
    2 Arete Proyectos, Mexico City, Mexico.
    Introduction: Treatment guidelines for schizophrenia represent a standard way to manage patients, especially in countries with limited staff resources. However, they have not been compared on their efficacy with treatment as usual, despite adult studies suggesting they can be more effective.

    Methods: Inpatient and outpatient adolescents with schizophrenia were randomly allocated to be either treated according to a guideline-based treatment ( n = 43) or treatment as usual ( n = 44). Read More

    Prevalence and correlates of suboptimal vitamin D status in people living with psychotic disorders: Data from the Australian Survey of High Impact Psychosis.
    Aust N Z J Psychiatry 2017 Sep 21;51(9):921-929. Epub 2016 Dec 21.
    1 Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, QLD, Australia.
    Objective: Having sufficient sera concentrations of 25-hydroxyvitamin D is important for a range of health outcomes including cardiometabolic diseases. Clinical studies in people with psychotic disorders suggest that a sizable proportion has suboptimal vitamin D status (i.e. Read More

    Mood stabilizers in pregnancy and child developmental outcomes: A systematic review.
    Aust N Z J Psychiatry 2017 Aug 1:4867417726175. Epub 2017 Aug 1.
    2 School of Psychology and Exercise Science, Murdoch University, Murdoch, WA, Australia.
    Background: Research suggests that maintaining treatment during pregnancy for women with bipolar affective disorder reduces the risk of relapse. However, one of the key questions for women and clinicians during pregnancy is whether there are implications of exposure to mood stabilizers for longer term child development. Despite these concerns, there are few recent systematic reviews comparing the impact on child developmental outcomes for individual mood-stabilizing agents to inform clinical decisions. Read More

    Social connectedness improves public mental health: Investigating bidirectional relationships in the New Zealand attitudes and values survey.
    Aust N Z J Psychiatry 2017 Aug 1:4867417723990. Epub 2017 Aug 1.
    2 School of Psychology, The University of Auckland, Auckland, New Zealand.
    Background: The importance of social connectedness in supporting public mental health is well established. However, the reverse causal pathway (that psychological ill-health leads to reduced social connectedness) remains a dominant perspective among mental health practitioners. Our analysis aimed to provide a rigorous test of the directionality of this relationship. Read More

    ALDH2 modulated changes in cytokine levels and cognitive function in bipolar disorder: A 12-week follow-up study.
    Aust N Z J Psychiatry 2017 Aug 1:4867417720517. Epub 2017 Aug 1.
    5 Department of Psychiatry, National Cheng Kung University Hospital, Tainan, Taiwan.
    Objectives: We investigated the association of the aldehyde dehydrogenase 2 ( ALDH2) polymorphism (rs671), which is involved with the dopaminergic function, and with changes in cytokine levels and cognitive function, in a 12-week follow-up study in patients with bipolar disorder.

    Methods: Patients with a first diagnosis of bipolar disorder were recruited. Symptom severity and levels of plasma cytokines (tumor necrosis factor α, C-reactive protein, interleukin 6 and transforming growth factor β1) were examined during weeks 0, 1, 2, 4, 8 and 12. Read More

    Psychotropic medication use in Australia, 2007 to 2015: Changes in annual incidence, prevalence and treatment exposure.
    Aust N Z J Psychiatry 2017 Jul 1:4867417721018. Epub 2017 Jul 1.
    1 Medicines Policy Research Unit, Centre for Big Data Research in Health, University of New South Wales, Sydney, NSW, Australia.
    Objective: To examine changes in annual patterns of psychotropic medication use in Australia from 2007 to 2015.

    Methods: We used a 10% sample of individual-level nationwide dispensing claims for concessional beneficiaries dispensed psychotropic medications (stratified by class, subclass) to investigate annual trends and changes in the incidence and prevalence of use, median annual duration of exposure, proportion of people with single psychotropic dispensing and median defined daily doses per person dispensed each medicine per year.

    Results: Over the study period, there was a 26. Read More

    Blockade of the angiotensin system improves mental health domain of quality of life: A meta-analysis of randomized clinical trials.
    Aust N Z J Psychiatry 2017 Jul 1:4867417721654. Epub 2017 Jul 1.
    11 IMPACT Strategic Research Centre, School of Medicine, Deakin University, Geelong, VIC, Australia.
    Objective: It is unclear whether blockade of the angiotensin system has effects on mental health. Our objective was to determine the impact of angiotensin converting enzyme inhibitors and angiotensin II type 1 receptor (AT1R) blockers on mental health domain of quality of life.

    Study Design: Meta-analysis of published literature. Read More

    Use of granulocyte-colony stimulating factor to prevent recurrent clozapine-induced neutropenia on drug rechallenge: A systematic review of the literature and clinical recommendations.
    Aust N Z J Psychiatry 2017 Jul 1:4867417720516. Epub 2017 Jul 1.
    2 School of Medicine, University of Queensland, St Lucia, QLD, Australia.
    Background: Clozapine is the most effective medication for treatment-refractory schizophrenia; however, its use is contraindicated in people who have had previous clozapine-induced neutropenia. Co-prescription of granulocyte-colony stimulating factor may prevent recurrent neutropenia and allow continuation or rechallenge of clozapine.

    Objective And Methods: Systematic review of literature reporting the use of granulocyte-colony stimulating factor to allow rechallenge or continuation of clozapine in people with previous episodes of clozapine-induced neutropenia. Read More

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