107,720 results match your criteria Australian and New Zealand Continence Journal [Journal]


Effect of Serial Anthropometric Measurements and Motivational Text Messages on Weight Reduction Among Workers: Pilot Randomized Controlled Trial.

JMIR Mhealth Uhealth 2019 Apr 24;7(4):e11832. Epub 2019 Apr 24.

School Of Medicine, University Centre for Rural Health, Western Sydney University, Lismore, Australia.

Background: Obesity is an endemic problem with significant health and financial consequences. Text messaging has been shown to be a simple and effective method of facilitating weight reduction. In addition, waist-to-hip ratio (WHR) has emerged as a significant anthropometric measure. Read More

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http://dx.doi.org/10.2196/11832DOI Listing

Rare plant species do not occupy water-remote refuges in arid environments subject to livestock grazing.

Ecol Appl 2019 Apr 24:e01911. Epub 2019 Apr 24.

School of Biological Sciences, University of Queensland, St Lucia, 4072, Queensland, Australia.

In many of the world's arid regions there has been a dramatic increase in grazing pressure with herds of livestock sustained by the provision of artificial water points. In these systems it has been suggested that grazing-sensitive plant species will have contracted to refuges distant from water points where grazing impacts are low. This association was tested using a large dataset of presence-absence records for rare plant species throughout the north-eastern Australian arid zone. Read More

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http://dx.doi.org/10.1002/eap.1911DOI Listing

A [C + C] route to propargylidyne complexes.

Dalton Trans 2019 Apr 24. Epub 2019 Apr 24.

Research School of Chemistry, The Australian National University, Canberra, ACT 2601, Australia.

The reactions of [W([triple bond, length as m-dash]CBr)(CO)2(Tp*)] (Tp* = hydrotris(dimethylpyrazolyl)borate) with a range of terminal alkynes (RC[triple bond, length as m-dash]CH), mediated by [Pd(PPh3)4] and CuI, afford new proparylidynes [W([triple bond, length as m-dash]C-C[triple bond, length as m-dash]CR)(CO)2(Tp*)] [R = tBu, C6H4X (X = H, NH2, NO2), ferrocenyl, APh3 (A = C, Si, Ge), B(O2CCH2)2NMe]. Similar treatment of [W([triple bond, length as m-dash]CBr)(CO)2(Tp*)] with Ph2Si(C[triple bond, length as m-dash]CH)2 affords the ditungstaoctatetrayne [W2(μ-C6)(CO)4(Tp*)2] while the bimetallic complex [W2{μ-([triple bond, length as m-dash]CC[triple bond, length as m-dash]C)2SiPh2}(CO)4(Tp*)2], which is obtained from [W([triple bond, length as m-dash]CBr)(CO)2(Tp*)] and Ph2Si(C[triple bond, length as m-dash]CSnPh3)2, reacts with [AuCl(THT)] (THT = tetrahydrothiophene) to provide the tetrametallic complex [W2Au2{μ-([triple bond, length as m-dash]CC[triple bond, length as m-dash]C)2SiPh2}Cl2(CO)4(Tp*)2]. Read More

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http://dx.doi.org/10.1039/c9dt00876dDOI Listing

Verifying alternative measures of healthcare service quality.

Int J Health Care Qual Assur 2019 Mar;32(2):516-533

American University in Cairo , Cairo, Egypt.

Purpose: The purpose of this paper is to determine the best measure among several alternatives (SERVQUAL, weighted SERVQUAL, SERVPERF, weighted SERVPERF) and develop a scale which healthcare providers can use for measurement of healthcare service quality.

Design/methodology/approach: The study involved two phases. The first phase was through a series of in-depth interviews with experts and patients followed by a pilot study. Read More

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http://dx.doi.org/10.1108/IJHCQA-05-2016-0069DOI Listing

Making errors at work due to sleepiness or sleep problems is not confined to non-standard work hours: results of the 2016 Sleep Health Foundation national survey.

Chronobiol Int 2019 Apr 24:1-12. Epub 2019 Apr 24.

c School of Exercise and Nutrition Sciences, Adelaide Institute of Sleep Health , Flinders University , Australia.

Almost one-third of Australians report having made errors at work that are related to sleep issues. While there is significant literature investigating the role of sleep in workplace health and safety in shiftworking and nightwork operations, long working hours, work-family conflict, and commute times getting longer also impact day workers' sleep behaviors and opportunities. The aim of this study was to examine the relationship between sleep duration and disorders, sleep health and hygiene factors, work-related factors and errors at work in Australian workers. Read More

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https://www.tandfonline.com/doi/full/10.1080/07420528.2019.1
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http://dx.doi.org/10.1080/07420528.2019.1578969DOI Listing
April 2019
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Development of a consumer experience reporting questionnaire for residential aged care homes in Australia.

Australas J Ageing 2019 Apr 23. Epub 2019 Apr 23.

Lincoln Centre for Research on Ageing, La Trobe University, Melbourne, Victoria, Australia.

Objective: To develop and pilot a short interview tool to be implemented by the Australian Aged Care Quality Agency (AACQA) in residential aged care, to inform prospective consumers about the quality of care and services received-the consumer experience report (CER).

Methods: Twenty-four questions addressing the four Aged Care Quality Standards were piloted with 140 residents and 48 representatives (including 27 resident-representative pairs). A method for approximating random selection was also trialled. Read More

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http://dx.doi.org/10.1111/ajag.12664DOI Listing

Review article: A primer for clinical researchers in the emergency department: Part VIII. Implementation science: An introduction.

Emerg Med Australas 2019 Apr 24. Epub 2019 Apr 24.

Nursing Research Institute, St Vincent's Health Australia and Australian Catholic University, Sydney, New South Wales, Australia.

New research findings may not lead to change in practice, or a change at the front line may be delayed by years. A number of terms have been used to describe efforts and strategies to speed a change in evidence-based practice, such as: implementation science, knowledge translation, research translation and others. In contrast to traditional clinical research, implementation science generally aims to understand and change health professional behaviour to promote evidence uptake as opposed to attempting to change patient behaviour. Read More

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http://dx.doi.org/10.1111/1742-6723.13296DOI Listing

Standardising the Classification of Harm Associated with Medication Errors: The Harm Associated with Medication Error Classification (HAMEC).

Drug Saf 2019 Apr 23. Epub 2019 Apr 23.

Centre for Health Systems and Safety Research, Australian Institute of Health Innovation, Macquarie University, Sydney, NSW, Australia.

Classifying harm associated with a medication error can be time consuming and labour intensive and limited studies undertake this step. There is no standardised process, and few studies that report harm assessment provide adequate methods to allow for study replication. Studies typically mention that a clinical review panel classified patient harm and provide a reference to a classification tool. Read More

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http://dx.doi.org/10.1007/s40264-019-00823-4DOI Listing

Diversity and Distribution of Bacteria Producing Known Secondary Metabolites.

Microb Ecol 2019 Apr 23. Epub 2019 Apr 23.

Centre for Marine Bio-Innovation and School of Biological, Earth and Environmental Sciences, The University of New South Wales Sydney, Sydney, NSW, Australia.

There is an increasing interest in the utilisation of marine bioactive compounds as novel biopharmaceuticals and agrichemicals; however, little is known about the environmental distribution for many of these molecules. Here, we aimed to elucidate the environmental distribution and to detect the biosynthetic gene clusters in environmental samples of four bioactive compounds, namely violacein, tropodithietic acid (TDA), tambjamine and the antibacterial protein AlpP. Our database analyses revealed high bacterial diversity for AlpP and violacein producers, while TDA-producing bacteria were mostly associated with marine surfaces and all belonged to the roseobacter group. Read More

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http://dx.doi.org/10.1007/s00248-019-01380-0DOI Listing

Bidirectional sliding of two parallel microtubules generated by multiple identical motors.

J Math Biol 2019 Apr 23. Epub 2019 Apr 23.

School of Mathematics and Physics, The University of Queensland, St. Lucia, QLD, 4072, Australia.

It is often assumed in biophysical studies that when multiple identical molecular motors interact with two parallel microtubules, the microtubules will be crosslinked and locked together. The aim of this study is to examine this assumption mathematically. We model the forces and movements generated by motors with a time-continuous Markov process and find that, counter-intuitively, a tug-of-war results from opposing actions of identical motors bound to different microtubules. Read More

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http://dx.doi.org/10.1007/s00285-019-01369-wDOI Listing

Outcome of atrial fibrillation ablation in pulmonary hypertension: Is pulmonary hypertension a modifiable risk factor?

Int J Cardiol Heart Vasc 2019 Jun 15;23:100360. Epub 2019 Apr 15.

Institute of Pharmacology, West German Heart and Vascular Center, University Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1016/j.ijcha.2019.100360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465768PMC

The profile of chiropractors managing patients with low back-related leg pain: analyses of 1907 chiropractors from the ACORN practice-based research network.

Chiropr Man Therap 2019 17;27:19. Epub 2019 Apr 17.

3Faculty of Health, University of Technology Sydney, Sydney, NSW Australia.

Background: Approximately 60% of people with low back pain also have associated leg pain symptoms. Guidelines for low back pain recommend non-pharmacological approaches, including spinal manipulation - a therapy provided by chiropractors. However, limited empirical data has examined the characteristics of chiropractors managing patients with low back-related leg pain (LBRLP). Read More

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http://dx.doi.org/10.1186/s12998-019-0239-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469207PMC

Pore-tuning to boost the electrocatalytic activity of polymeric micelle-templated mesoporous Pd nanoparticles.

Chem Sci 2019 Apr 12;10(14):4054-4061. Epub 2019 Mar 12.

Key Laboratory of Eco-chemical Engineering , College of Chemistry and Molecular Engineering , Qingdao University of Science and Technology (QUST) , Qingdao 266042 , China.

Understanding how mesoporous noble metal architectures affect electrocatalytic performance is very important for the rational design and preparation of high-performance electrocatalysts. Herein, by using polymeric micelle-assembled structures as templates, mesoporous Pd nanoparticles with tunable porous constructions are synthesized by simply tuning the solvent compositions. The effect of porous Pd nanoparticles on the electrocatalytic performance is thoroughly studied. Read More

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http://dx.doi.org/10.1039/c8sc03911aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457336PMC

Expanding the role of Australian pharmacists in community pharmacies in chronic pain management - a narrative review.

Pharm Pract (Granada) 2019 Jan-Mar;17(1):1410. Epub 2019 Feb 18.

School of Health and Biomedical Sciences, Discipline of Pharmacy, RMIT University. Bundoora, VIC (Australia).

Chronic pain is a condition where patients continuously experience pain symptoms for at least 3 to 6 months. It is one of the leading causes of disabilities across the globe. Failure to adequately manage chronic pain often results in additional health concerns that may directly contribute to the worsening symptoms of pain. Read More

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http://dx.doi.org/10.18549/PharmPract.2019.1.1410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463420PMC
February 2019

Psychological Sleep Interventions for Migraine and Tension-Type Headache: A Systematic Review and Meta-Analysis.

Sci Rep 2019 Apr 23;9(1):6411. Epub 2019 Apr 23.

School of Applied Psychology and Menzies Health Institute Queensland, Griffith University, Mount Gravatt, Australia.

Disordered sleep, poor sleep quality, and insufficient or excessive sleep duration are known triggers of primary and secondary headaches. Given this, it is plausible that improving sleep will subsequently reduce headache activity. We report a systematic review of the literature, examining studies utilising psychological sleep interventions for the treatment of migraine and tension-type headache. Read More

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http://dx.doi.org/10.1038/s41598-019-42785-8DOI Listing

KCC1 Activation protects Mice from the Development of Experimental Cerebral Malaria.

Sci Rep 2019 Apr 23;9(1):6356. Epub 2019 Apr 23.

Department of Immunology and Infectious Disease, John Curtin School of Medical Research, Australian National University, Australian Capital Territory, Australia.

Plasmodium falciparum malaria causes half a million deaths per year, with up to 9% of this mortality caused by cerebral malaria (CM). One of the major processes contributing to the development of CM is an excess of host inflammatory cytokines. Recently K+ signaling has emerged as an important mediator of the inflammatory response to infection; we therefore investigated whether mice carrying an ENU induced activation of the electroneutral K+ channel KCC1 had an altered response to Plasmodium berghei. Read More

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http://dx.doi.org/10.1038/s41598-019-42782-xDOI Listing

Mice lacking Casp1, Ifngr and Nos2 genes exhibit altered depressive- and anxiety-like behaviour, and gut microbiome composition.

Sci Rep 2019 Apr 23;9(1):6456. Epub 2019 Apr 23.

Mind and Brain Theme, South Australian Health and Medical Research Institute, Adelaide, SA, Australia.

Converging evidence supports the involvement of pro-inflammatory pathways and the gut microbiome in major depressive disorder (MDD). Pre-clinical and clinical studies suggest that decreasing pro-inflammatory signaling may provide clinical benefit in MDD. In this study, we used the chronic unpredictable stress (CUS) paradigm to assess whether mice lacking the pro-inflammatory caspase 1, interferon gamma-receptor, and nitric oxide synthase (Casp1, Ifngr, Nos2) present altered depressive- and anxiety-like behaviour at baseline and in response to CUS. Read More

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http://dx.doi.org/10.1038/s41598-018-38055-8DOI Listing

Thermally robust spin correlations between two Rb atoms in an optical microtrap.

Nat Commun 2019 Apr 23;10(1):1889. Epub 2019 Apr 23.

The Dodd-Walls Centre for Photonic and Quantum Technologies, Department of Physics, University of Otago, Dunedin, New Zealand.

The complex collisional properties of atoms fundamentally limit investigations into a range of processes in many-atom ensembles. In contrast, the bottom-up assembly of few- and many-body systems from individual atoms offers a controlled approach to isolating and studying such collisional processes. Here, we use optical tweezers to individually assemble pairs of trapped Rb atoms, and study the spin dynamics of the two-body system in a thermal state. Read More

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http://dx.doi.org/10.1038/s41467-019-09420-6DOI Listing

The Structural Basis for a Transition State That Regulates Pore Formation in a Bacterial Toxin.

MBio 2019 Apr 23;10(2). Epub 2019 Apr 23.

Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA

The cholesterol-dependent cytolysin (CDC) genes are present in bacterial species that span terrestrial, vertebrate, and invertebrate niches, which suggests that they have evolved to function under widely different environmental conditions. Using a combination of biophysical and crystallographic approaches, we reveal that the relative stability of an intramolecular interface in the archetype CDC perfringolysin O (PFO) plays a central role in regulating its pore-forming properties. The disruption of this interface allows the formation of the membrane spanning β-barrel pore in all CDCs. Read More

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http://dx.doi.org/10.1128/mBio.00538-19DOI Listing

Balancing the Hype with Reality: What Do Patients with Advanced Melanoma Consider When Making the Decision to Have Immunotherapy?

Oncologist 2019 Apr 23. Epub 2019 Apr 23.

Department of Cancer Experiences Research, Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, Australia

Background: Immunotherapy has resulted in unprecedented improvements in survival and maintained quality of life for many patients with advanced melanoma. However, durable responses are observed in only a minority of patients, and severe treatment side effects are experienced by 5%-30%. There are no reliable tests that can differentiate between patients who are likely to respond to immunotherapy and those who will not. Read More

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http://theoncologist.alphamedpress.org/lookup/doi/10.1634/th
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http://dx.doi.org/10.1634/theoncologist.2018-0820DOI Listing
April 2019
2 Reads

Carbon dots: Applications in Bioimaging and Theranostics.

Int J Pharm 2019 Apr 20. Epub 2019 Apr 20.

Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China. Electronic address:

Carbon dots are a carbonaceous nanomaterial that were discovered accidentally and are now drawing significant attention as a new quantum-sized fluorescent nanoparticle. Carbon dots are biocompatible, non-toxic, photostable, and easily functionalized with good photoluminescence and water solubility. Due to these unique properties, they are used broadly in live cell imaging, catalysis, electronics, biosensing, power, targeted drug delivery, and other biomedical applications. Read More

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http://dx.doi.org/10.1016/j.ijpharm.2019.04.055DOI Listing

Cats as potential mammalian reservoirs for Rickettsia sp. genotype RF2125 in Bangkok, Thailand.

Vet Parasitol Reg Stud Reports 2018 Aug 3;13:188-192. Epub 2018 Jul 3.

Department of Parasitology, Faculty of Veterinary Medicine, Kasetsart University, Bangkok, Thailand. Electronic address:

Rickettsia felis is an obligate intracellular alpha-proteobacteria and the cause of flea-borne spotted fever (FBSF), an emerging zoonosis of global public health importance, for which dogs and cats have been implicated as potential mammalian reservoirs hosts. The purpose of this study was to determine the prevalence and associated risk factors for R. felis-like species in semi-domesticated cats and their fleas in aim of understanding public health risks posed by cats and their fleas in Bangkok, Thailand. Read More

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http://dx.doi.org/10.1016/j.vprsr.2018.07.001DOI Listing

Proactive treatment of angiotensin receptor antibodies in kidney transplantation with plasma exchange and/or candesartan is safe and associated with excellent graft survival at 4 years: A single centre Australian experience.

Hum Immunol 2019 Apr 20. Epub 2019 Apr 20.

South Australian Tissue Typing and Immunogenetics Service, Australian Red Cross Blood Service (ARCBS), Adelaide, South Australia, Australia; Central Northern Adelaide Renal and Transplantation Services (CNARTS), Royal Adelaide Hospital, Adelaide, South Australia, Australia.

High levels of angiotensin receptor antibodies (ATRab) are associated with acute cellular and humoral rejection, vascular occlusion, de novo human leucocyte antigen donor specific antibody (HLA DSA) and poor graft survival in kidney transplant recipients (KTR). Since 2015 we proactively managed patients "at risk" (AR) with ATRab >17 U/ml with perioperative plasma exchange (PLEX) and/or angiotensin receptor blockade (ARB). 44 patients were treated with this protocol. Read More

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http://dx.doi.org/10.1016/j.humimm.2019.04.005DOI Listing

Development of New Proliferative Diabetic Retinopathy in the BEVORDEX Trial.

Ophthalmol Retina 2019 Mar 25;3(3):286-287. Epub 2018 Oct 25.

Macular Research Group, Save Sight Institute, University of Sydney, Sydney, Australia; Sydney Eye Hospital, Sydney, Australia.

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http://dx.doi.org/10.1016/j.oret.2018.10.010DOI Listing

Elevated Triglycerides to High-Density Lipoprotein Cholesterol (TG/HDL-C) Ratio Predicts Long-Term Mortality in High-Risk Patients.

Heart Lung Circ 2019 Apr 16. Epub 2019 Apr 16.

Department of Cardiology, St. Vincent's Hospital, Melbourne, Vic, Australia; Department of Cardiology, St. Vincent's Private Hospital, Melbourne, Vic, Australia.

Background: Elevated triglycerides to high-density lipoprotein cholesterol (TG/HDL-C) ratio has been utilised as a predictor of outcomes in patients with adverse cardiometabolic risk profiles. In this study, we examined the prognostic value of elevated TG/HDL-C level in an Australian population of patients with high clinical suspicion of coronary artery disease (CAD) presenting for coronary angiography.

Methods: Follow-up data was collected for 482 patients who underwent coronary angiography in a prospective cohort study. Read More

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http://dx.doi.org/10.1016/j.hlc.2019.03.019DOI Listing

The Alternative Splicing Regulator Nova2 Constrains Vascular Erk Signaling to Limit Specification of the Lymphatic Lineage.

Dev Cell 2019 Apr;49(2):279-292.e5

Division of Genomics of Development and Disease, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, QLD 4073, Australia. Electronic address:

The correct assignment of cell fate within fields of multipotent progenitors is essential for accurate tissue diversification. The first lymphatic vessels arise from pre-existing veins after venous endothelial cells become specified as lymphatic progenitors. Prox1 specifies lymphatic fate and labels these progenitors; however, the mechanisms restricting Prox1 expression and limiting the progenitor pool remain unknown. Read More

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http://dx.doi.org/10.1016/j.devcel.2019.03.017DOI Listing

Response to the Letter to the Editor by Harris.

Parasit Vectors 2019 Apr 24;12(1):178. Epub 2019 Apr 24.

Vector and Waterborne Pathogens Research Group, College of Science, Health, Engineering and Education, Perth, WA, Australia.

In a letter to the Editor, Harris considers the eight new species of Apicomplexa that were recently identified and named to be invalid on the basis that only molecular characters were provided in the species descriptions. In this response, we counter that the species names are valid as the descriptions have met the requirements of the International Code of Zoological Nomenclature; molecular characters can be used to satisfy article 13.1. Read More

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http://dx.doi.org/10.1186/s13071-019-3439-2DOI Listing

Genomic sequence analysis reveals diversity of Australian Xanthomonas species associated with bacterial leaf spot of tomato, capsicum and chilli.

BMC Genomics 2019 Apr 23;20(1):310. Epub 2019 Apr 23.

Agriculture Victoria Research Division, Department of Economic Development, Jobs, Transport & Resources, AgriBio, La Trobe University, Bundoora, Victoria, 3083, Australia.

Background: The genetic diversity in Australian populations of Xanthomonas species associated with bacterial leaf spot in tomato, capsicum and chilli were compared to worldwide bacterial populations. The aim of this study was to confirm the identities of these Australian Xanthomonas species and classify them in comparison to overseas isolates. Analysis of whole genome sequence allows for the investigation of bacterial population structure, pathogenicity and gene exchange, resulting in better management strategies and biosecurity. Read More

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http://dx.doi.org/10.1186/s12864-019-5600-xDOI Listing

Marine reserves shape seascapes on scales visible from space.

Proc Biol Sci 2019 Apr;286(1901):20190053

1 Department of Biological Sciences, Macquarie University , Sydney, New South Wales 2109 , Australia.

Marine reserves can effectively restore harvested populations, and 'mega-reserves' increasingly protect large tracts of ocean. However, no method exists of monitoring ecological responses at this large scale. Herbivory is a key mechanism structuring ecosystems, and this consumer-resource interaction's strength on coral reefs can indicate ecosystem health. Read More

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http://www.royalsocietypublishing.org/doi/10.1098/rspb.2019.
Publisher Site
http://dx.doi.org/10.1098/rspb.2019.0053DOI Listing
April 2019
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Conceptualizing the Association Between Community Participation and CQI in Aboriginal and Torres Strait Islander PHC Services.

Qual Health Res 2019 Apr 23:1049732319843107. Epub 2019 Apr 23.

4 The University of Sydney, University Centre for Rural Health, Lismore, New South Wales, Australia.

Drawing from Australian Aboriginal and Torres Strait Islander perspectives, we conceptualize the association between community participation and continuous quality improvement (CQI) processes in Indigenous primary health care (PHC) services. Indigenous experiences of community participation were drawn from our study identifying contextual factors affecting CQI processes in high-improving PHC services. Using case study design, we collected quantitative and qualitative data at the micro-, meso-, and macro-health system level in 2014 and 2015 in six services in northern Australia. Read More

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http://dx.doi.org/10.1177/1049732319843107DOI Listing

Baseline fasting plasma insulin levels predict risk for major adverse cardiovascular events among patients with diabetes and high-risk vascular disease: Insights from the ACCELERATE trial.

Diab Vasc Dis Res 2019 Mar;16(2):171-177

1 Heart and Vascular Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.

Background: Despite optimal treatment, type II diabetes mellitus remains associated with an increased risk for future cardiovascular events. We sought to determine the association between baseline fasting plasma insulin levels and major adverse cardiovascular outcomes in patients with type II diabetes mellitus and high-risk vascular disease enrolled in the ACCELERATE (Assessment of Clinical Effects of Cholesteryl Ester Transfer Protein Inhibition with Evacetrapib in Patients at a High Risk for Vascular Outcomes) trial.

Methods: We included all patients with type II diabetes mellitus who had a central laboratory measured fasting plasma insulin level drawn at baseline as part of the study protocol. Read More

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http://dx.doi.org/10.1177/1479164119827604DOI Listing
March 2019
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Fabrication of Highly Conductive Porous Cellulose/PEDOT:PSS Nanocomposite Paper via Post-Treatment.

Nanomaterials (Basel) 2019 Apr 13;9(4). Epub 2019 Apr 13.

Department of Plant & Environmental New Resources, Kyung Hee University, 1732 Deogyeong-daero, Giheung-gu, Yongin-si, Gyeonggi-do 446-701, Korea.

In this paper, we report the fabrication of highly conductive poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate) (PEDOT:PSS)/cellulose nanofiber (CNF) nanocomposite paper with excellent flexibility through post-treatment with an organic solvent. The post-treated PEDOT:PSS/CNF porous nanocomposite papers showed a lower sulfur content, indicating the removal of residual PSS. The electrical conductivity of PEDOT:PSS/CNF porous nanocomposite paper was increased from 1. Read More

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http://dx.doi.org/10.3390/nano9040612DOI Listing

Schistosomiasis in the Philippines: Innovative Control Approach is Needed if Elimination is the Goal.

Trop Med Infect Dis 2019 Apr 13;4(2). Epub 2019 Apr 13.

Research School of Population Health, Australian National University, Canberra 2601, Australia.

In 1996, schistosomiasis due to was declared eradicated in Japan. In the People's Republic of China, transmission has been interrupted in the major endemic areas in the coastal plains but the disease persists in the lake and marshland regions south of the Yangtze River. The disease remains a public health problem in endemic areas in the Philippines and in isolated areas in Indonesia. Read More

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http://dx.doi.org/10.3390/tropicalmed4020066DOI Listing

The Food Literacy Action Logic Model: A Tertiary Education Sector Innovative Strategy to Support the Charitable Food Sectors Need for Food Literacy Training.

Nutrients 2019 Apr 12;11(4). Epub 2019 Apr 12.

School of Medical and Health Sciences, Edith Cowan University, Joondalup, Perth, WA 6027, Australia.

Food literacy is seen as a key component in improving the increasing levels of food insecurity. While responsibility for providing training falls on the charitable service organizations, they may not have the capacity to adequately reach those in need. This paper proposes a tertiary education - (university or higher education) led model to support the food literacy training needs of the food charity sector. Read More

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http://dx.doi.org/10.3390/nu11040837DOI Listing

Using Patient-Reported Outcomes to Predict Revision Arthroplasty Following Femoral Neck Fracture: Enhancing the Value of Clinical Registries through Data Linkage.

Int J Environ Res Public Health 2019 Apr 12;16(8). Epub 2019 Apr 12.

Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia.

The aim of this study was to determine the association between patient-reported outcome measures (PROMs) six months following femoral neck fracture after a low fall and future arthroplasty, and the factors associated with this. Six-month post-fracture PROMs were collected from the Victorian Orthopaedic Trauma Outcomes Registry (VOTOR) for patients aged >55 years who were admitted for a femoral neck fracture after a low fall between March 2007 and June 2015. These cases were linked with those registered by Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR) up to October 2016. Read More

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http://dx.doi.org/10.3390/ijerph16081325DOI Listing

The return of the frogs: The importance of habitat refugia in maintaining diversity during a disease outbreak.

Mol Ecol 2019 Apr 23. Epub 2019 Apr 23.

College of Science and Engineering, James Cook University, Townsville, QLD, 4811, Australia.

Recent decades have seen the emergence and spread of numerous infectious diseases, often with severe negative consequences for wildlife populations. Nevertheless, many populations survive the initial outbreaks, and even undergo recoveries. Unfortunately, the long-term effects of these outbreaks on host population genetics are poorly understood; to increase this understanding, we examined the population genetics of two species of rainforest frogs (Litoria nannotis and Litoria serrata) that have largely recovered from a chytridiomycosis outbreak at two national parks in the Wet Tropics of northern Australia. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/mec.15108
Publisher Site
http://dx.doi.org/10.1111/mec.15108DOI Listing
April 2019
1 Read

Australian Aboriginal children have higher hospitalization rates for otitis media but lower surgical procedures than non-Aboriginal children: A record linkage population-based cohort study.

PLoS One 2019 23;14(4):e0215483. Epub 2019 Apr 23.

Wesfarmers Centre for Vaccines and Infectious Diseases, Telethon Kids Institute, The University of Western Australia, Perth, Western Australia, Australia.

Introduction: Otitis media (OM) is one of the most common infectious diseases affecting children globally and the most common reason for antibiotic prescription and paediatric surgery. Australian Aboriginal children have higher rates of OM than non-Aboriginal children; however, there are no data comparing OM hospitalization rates between them at the population level. We report temporal trends for OM hospitalizations and in-hospital tympanostomy tube insertion (TTI) in a cohort of 469,589 Western Australian children born between 1996 and 2012. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215483PLOS
April 2019
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Group B streptococcus prevalence, serotype distribution and colonization dynamics in Western Australian pregnant women.

J Med Microbiol 2019 Apr 23. Epub 2019 Apr 23.

1 The School of Medicine, Division of Obstetrics and Gynaecology, The University of Western Australia, Australia.

Purpose: Streptococcus agalactiae, or group B streptococcus (GBS), is a leading neonatal pathogen that causes sepsis, meningitis and pneumonia. Globally, strategies have been implemented to address vertical transmission, and in Western Australia (WA), culture-based screening at 35-37 weeks' gestation is part of routine care and guides antibiotic administration. Previous Australian studies have focused on other regions or included low sample-size representatives; we aimed to describe antenatal GBS colonization in WA. Read More

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https://www.microbiologyresearch.org/content/journal/jmm/10.
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http://dx.doi.org/10.1099/jmm.0.000980DOI Listing
April 2019
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Application of Low-Frequency Raman Scattering Spectroscopy to Probe in Situ Drug Solubilization in Milk during Digestion.

J Phys Chem Lett 2019 Apr 23:2258-2263. Epub 2019 Apr 23.

Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences , Monash University (Parkville Campus) , 381 Royal Parade , Parkville , VIC 3052 , Australia.

We have recently shown that real-time monitoring of drug solubilization and changes to solid state of the drug during digestion of milk can be achieved using synchrotron small-angle X-ray scattering. A complementary laboratory-based method to explore such changes is low-frequency Raman spectroscopy, which has been increasingly used to characterize crystalline drugs and their polymorphs in powders and suspensions. This study investigates the use of this technique to monitor in situ drug solubilization in milk during the process of digestion, using a lipolysis model/flow-through configuration identical to that used previously for in situ synchrotron small-angle X-ray scattering studies. Read More

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http://dx.doi.org/10.1021/acs.jpclett.9b00654DOI Listing

Extended-spectrum β-lactamase in the rectal flora of patients undergoing transrectal prostate biopsy: a study of the prevalence in a major metropolitan hospital.

BJU Int 2019 Apr 23. Epub 2019 Apr 23.

Department of Urology, Royal Melbourne Hospital, Parkville, Vic., Australia.

Objectives: To determine the prevalence of extended-spectrum β-lactamase (ESBL) in patients undergoing transrectal prostate biopsy, to assess the incidence of postoperative sepsis, to correlate the development of sepsis with the presence of preoperative ESBL on rectal swabs, and to assess the adequacy of prophylactic antibiotic guidelines in the context of local ESBL prevalence.

Methods: Patients undergoing transrectal ultrasonography (TRUS)-guided biopsy at the Royal Melbourne Hospital between January 2012 and July 2016 had rectal swabs taken immediately prior to TRUS with specific cultures to identify the presence of ESBL. Patients were given a prophylactic antibiotic, 500 mg oral ciprofloxacin, 1 h before the TRUS procedure. Read More

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http://dx.doi.org/10.1111/bju.14745DOI Listing

A randomized controlled trial of a wearable technology-based intervention for increasing moderate to vigorous physical activity and reducing sedentary behavior in breast cancer survivors: The ACTIVATE Trial.

Cancer 2019 Apr 23. Epub 2019 Apr 23.

Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia.

Background: The benefits of an active lifestyle after a breast cancer diagnosis are well recognized, but the majority of survivors are insufficiently active. The ACTIVATE Trial examined the efficacy of an intervention (use of the Garmin Vivofit 2 activity monitor coupled with a behavioral feedback and goal-setting session and 5 telephone-delivered health coaching sessions) to increase moderate to vigorous physical activity (MVPA) and reduce sedentary behavior in breast cancer survivors.

Methods: This randomized controlled trial recruited 83 inactive, postmenopausal women diagnosed with stage I-III breast cancer who had completed primary treatment. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/cncr.32143
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http://dx.doi.org/10.1002/cncr.32143DOI Listing
April 2019
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Maintenance of physical activity and sedentary behavior change, and physical activity and sedentary behavior change after an abridged intervention: Secondary outcomes from the ACTIVATE Trial.

Cancer 2019 Apr 23. Epub 2019 Apr 23.

Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia.

Background: This brief report examines the maintenance of moderate to vigorous physical activity (MVPA) and sedentary behavior changes approximately 12 weeks after the delivery of the ACTIVATE Trial primary intervention (use of the Garmin Vivofit 2 activity tracker coupled with a behavioral feedback and goal-setting session and 5 telephone-delivered health coaching sessions). We also examine the efficacy of an abridged intervention (use of the Garmin Vivofit 2 only) in the waitlist control group.

Methods: A pre-post design was employed to examine the secondary aims of the ACTIVATE Trial (n = 80; mean age = 62 years). Read More

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http://dx.doi.org/10.1002/cncr.32142DOI Listing

Photochemical Etching of Carbonyl Groups from a Carbon Matrix: The (001) Diamond Surface.

Phys Rev Lett 2019 Jan;122(1):016802

MQ Photonics Research Centre, Department of Physics and Astronomy, Macquarie University, New South Wales 2109, Australia.

The surface of diamond is reported to undergo nonablative photochemical etching when exposed to ultraviolet (UV) radiation which allows controlled single and partial layer removal of lattice layers. Oxygen termination of surface dangling bonds is known to be crucial for the etching process; however, the exact mechanism of carbon ejection remains unclear. We investigate the interaction of UV laser pulses with oxygen-terminated diamond surfaces using atomic-scale surface characterization combined with first-principles time-dependent density functional theory calculations. Read More

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http://dx.doi.org/10.1103/PhysRevLett.122.016802DOI Listing
January 2019

Foliar water uptake in Amazonian trees: evidence and consequences.

Glob Chang Biol 2019 Apr 23. Epub 2019 Apr 23.

Research School of Biology, The Australian National University, Canberra, 2601 ACT, Australia.

The absorption of atmospheric water directly into leaves enables plants to alleviate the water stress caused by low soil moisture, hydraulic resistance in the xylem and the effect of gravity on the water column, whilst enabling plants to scavenge small inputs of water from leaf wetting events. By increasing the availability of water, and supplying it from the top of the canopy (in a direction facilitated by gravity), foliar uptake (FU) may be a significant process in determining how forests interact with climate, and could alter our interpretation of current metrics for hydraulic stress and sensitivity. FU has not been reported for lowland tropical rain forests; we test whether FU occurs in six common Amazonian tree genera in lowland Amazônia, and make a first estimation of its contribution to canopy-atmosphere water exchange. Read More

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http://dx.doi.org/10.1111/gcb.14666DOI Listing

Noncoding Variations in the Gene Encoding Ceramide Synthase 6 are Associated with Type 2 Diabetes in a Large Indigenous Australian Pedigree.

Twin Res Hum Genet 2019 Apr 23:1-9. Epub 2019 Apr 23.

Diabetes Research Laboratories, School of Clinical Medicine Prince Charles Hospital Northside Clinical Unit, Faculty of Medicine,University of Queensland,Brisbane,Queensland,Australia.

Type 2 diabetes (T2D) is a chronic disease that disproportionately affects Indigenous Australians. We have previously reported the localization of a novel T2D locus by linkage analysis to chromosome 2q24 in a large admixed Indigenous Australian pedigree (Busfield et al. (2002). Read More

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http://dx.doi.org/10.1017/thg.2019.13DOI Listing

A systematic review of the approaches to multi-level learning in the general practice context, using a realist synthesis approach: BEME Guide No. 55.

Med Teach 2019 Apr 23:1-15. Epub 2019 Apr 23.

c Faculty of Arts and Social Sciences, University of Technology Sydney , Australia.

Background: Recent global increases in medical student numbers and shifts in medical education from teaching hospitals to community settings call for effective strategies to meet the demand for general practice teaching placements. It has been proposed that "multi-level learning" (MLL), in which learning and teaching are shared across different levels of learners, may provide teaching efficiencies and valuable experiences for learners and teachers.

Aims: To identify, evaluate and synthesize the evidence related to the types, benefits, challenges, and facilitators of MLL in community-based general practice, and the underlying mechanisms and associated contexts to explain the reported outcomes. Read More

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http://dx.doi.org/10.1080/0142159X.2019.1595554DOI Listing

Outcomes of universal germline testing for men with prostate cancer in an Australian tertiary center.

Asia Pac J Clin Oncol 2019 Apr 22. Epub 2019 Apr 22.

Kinghorn Cancer Centre, St. Vincent's Hospital, Darlinghurst, NSW, Australia.

Aim: The role of germline testing in prostate cancer is evolving and knowledge of an individual's genetic profile may be used to guide not only an assessment of their familial risk but also have prognostic and therapeutic implications. Although international guidelines have incorporated recommendations for germline testing in prostate cancer, there is little Australian data to guide referrals. The aim of this study is to review the frequency of relevant pathogenic mutations in an Australian center, their associated clinical factors and clinical impact. Read More

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http://dx.doi.org/10.1111/ajco.13148DOI Listing

Experiences and perceptions of residential and home care services among older lesbian women and gay men in Australia.

Health Soc Care Community 2019 Apr 22. Epub 2019 Apr 22.

National LGBTI Health Alliance, Sydney, NSW, Australia.

The needs of older lesbian and gay people regarding access and use of aged-care services remain underresearched. This paper reports the findings of 33 qualitative interviews with older lesbian women and gay men about their perceptions and experiences of residential aged-care and home-based aged-care services in Australia. The focus of this paper is their preparedness for using aged-care services. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/hsc.12760
Publisher Site
http://dx.doi.org/10.1111/hsc.12760DOI Listing
April 2019
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Interleukin-22: friend or foe?

Immunol Cell Biol 2019 Apr;97(4):355-357

Inflammatory Bowel Disease Group, Mater Research institute-The University of Queensland, Translational Research Institute, Brisbane, QLD, Australia.

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http://dx.doi.org/10.1111/imcb.12249DOI Listing

Educator as Diagnostician, Judge and Confidant: a positioning analysis of medical student support encounters.

Adv Health Sci Educ Theory Pract 2019 Apr 22. Epub 2019 Apr 22.

Department of Medical Education, Melbourne Medical School, University of Melbourne, Parkville, VIC, 3052, Australia.

Medical schools, programs and educators are increasingly expected to address medical student stress and wellbeing, yet also ensure student competence and fitness to practice. Educators play a central role in supporting students when evaluating a student's concerns and in deciding whether support and/or sanction should be offered. It is not known how educators approach or resolve such potentially contradictory responses. Read More

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http://dx.doi.org/10.1007/s10459-019-09892-7DOI Listing