103,543 results match your criteria Australian Veterinary Journal [Journal]


The development of anticipatory action planning in children with unilateral cerebral palsy.

Res Dev Disabil 2018 Dec 14;85:163-171. Epub 2018 Dec 14.

Department of Paediatrics, Monash University, Clayton, Victoria, 3168, Australia; School of Occupational Therapy, La Trobe University, Bundoora, Victoria, 3168, Australia; Victorian Paediatric Rehabilitation Service, Monash Children's Hospital, 246 Clayton Rd, Clayton, Victoria, 3168, Australia. Electronic address:

Background Previous studies suggest that compromised bimanual performance experienced by children with unilateral cerebral palsy (CP) is not only due to difficulties in action execution but may also be a result of impaired anticipatory action planning. Aims The effect of age and side of hemiplegia were examined and the relationship between anticipatory action planning, unimanual capacity and bimanual performance was explored. Methods and procedures Using a multi-centre, prospective, cross-sectional observational design, anticipatory action planning was analyzed in 104 children with unilateral cerebral palsy, aged 6-12 years, using the sword task. Read More

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December 2018
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Current perspectives of Australian therapists on rehabilitation and return to sport after anterior cruciate ligament reconstruction: A survey.

Phys Ther Sport 2018 Dec 10;35:139-145. Epub 2018 Dec 10.

Perth Orthopaedic and Sports Medicine Centre, West Perth, Western Australia, Australia.

Objectives: To investigate views and practices of Australian therapists on rehabilitation and return to sport (RTS) after anterior cruciate ligament reconstruction (ACLR).

Design: Survey-based study.

Setting: Online survey platform. Read More

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December 2018

Breaking habits with mindful snacking? An email-based intervention targeting unwanted snacking habits in an Australian sample.

Eat Behav 2018 Nov 30;32:37-43. Epub 2018 Nov 30.

CSIRO, Health and Biosecurity, Kintore Ave, Adelaide 5001, Australia.

Objective: To investigate the potential for an email-based, mindful eating exercise to improve unwanted snacking habits.

Method: Australian participants (N = 78, 86% female) with unwanted snacking habits engaged in a mindful eating email-based intervention, over a practice period of two weeks. All measures were completed using an online survey. Read More

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November 2018

A mouse model for intellectual disability caused by mutations in the X-linked 2'‑O‑methyltransferase Ftsj1 gene.

Biochim Biophys Acta Mol Basis Dis 2018 Dec 14. Epub 2018 Dec 14.

Department of Functional Genomics, Interfaculty Institute of Genetics and Functional Genomics, University Medicine Greifswald, Felix-Hausdorff-Strasse 8, 17489 Greifswald, Germany.

Mutations in the X chromosomal tRNA 2'‑O‑methyltransferase FTSJ1 cause intellectual disability (ID). Although the gene is ubiquitously expressed affected individuals present no consistent clinical features beyond ID. In order to study the pathological mechanism involved in the aetiology of FTSJ1 deficiency-related cognitive impairment, we generated and characterized an Ftsj1 deficient mouse line based on the gene trapped stem cell line RRD143. Read More

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December 2018

Cerebrospinal fluid ferritin levels predict brain hypometabolism in people with underlying β-amyloid pathology.

Neurobiol Dis 2018 Dec 14. Epub 2018 Dec 14.

Melbourne Dementia Research Centre, The Florey Institute for Neuroscience and Mental Health, The University of Melbourne, Victoria, Australia; Cooperative Research Center for Mental Health, Victoria, Australia. Electronic address:

β-Amyloid pathology is elevated in ~30% of cognitively normal people over 65, and is associated with accelerated neurodegeneration in the pre-clinical stages of Alzheimer's disease. Recent findings reveal that brain iron might also act to propel neurodegeneration in people with underlying amyloid pathology. Here, repeated PET scans of fluorodeoxyglucose (FDG) were used as a biomarker for brain hypometabolism and a downstream biomarker of neurodegeneration to investigate whether levels of ferritin in the cerebrospinal fluid (CSF; a reporter of brain iron load) are associated with prodromal disease progression of people with high β-amyloid pathology determined by established cut-off values in CSF t-tau/Aβ ratio. Read More

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December 2018

The relationship between pressure ulcer risk assessment and preventative interventions: a systematic review.

J Wound Care 2018 Dec;27(12):862-875

Professor of Nursing, School of Nursing, Midwifery and Paramedicine, Faculty of Health Sciences, Australian Catholic University, 1100 Nudgee Road, Banyo, QLD, Australia 4014. Nursing Research and Practice Development Centre, The Prince Charles Hospital, Rode Rd, Chermside, QLD, Australia 4032. Faculty of Health Sciences, University of Witwatersrand, South Africa.

Objective:: Hospital-acquired pressure ulcers (PU) continue to occur despite an ongoing focus on prevention. The aim of this review was to identify and evaluate primary research which links pressure ulcer risk assessment with prescription and implementation of preventative interventions for hospitalised adults.

Method:: A systematic review of the databases EBSCO CINAHL Complete, EBSCO MEDLINE Complete, Scopus and Web of Science was undertaken, using search terms related to pressure ulcers, hospital-acquired, risk, planning, implementation, prevention and outcome. Read More

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December 2018

The effect of hospitalization on potentially inappropriate medication use in older adults with chronic kidney disease.

Curr Med Res Opin 2018 Dec 17:1-18. Epub 2018 Dec 17.

a Pharmacy, School of Medicine, College of Health and Medicine, University of Tasmania , Australia.

Objectives: Potentially inappropriate medications (PIMs) use is associated with increased morbidity and mortality in chronic kidney disease (CKD). However, there is paucity of data on how hospitalization affects PIMs use in older adults with CKD. Therefore, we aimed to measure the impact of hospitalization on PIMs use in older CKD patients, and identify factors predicting PIMs use. Read More

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December 2018

Lanthanoid Heteroleptic Complexes with Cucurbit[5]uril and Dicarboxylate Ligands: From Discrete Structures to One-Dimensional and Two-Dimensional Polymers.

Inorg Chem 2018 Dec 17. Epub 2018 Dec 17.

CSIRO Manufacturing , P.O. Box 218, Lindfield , New South Wales 2070 , Australia.

Lanthanoid heteroleptic complexes with cucurbit[5]uril {Q[5]} and two dicarboxylate ligands, e.g., diglycolic acid (HDGC) and glutaric acid (HGT), have been investigated with six new compounds featuring a tetrametallic and dimetallic discrete structures, a one-dimensional (1D) polymer, and three two-dimensional (2D) polymers with a unique honeycomb-type topology being synthesized and structurally characterized. Read More

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December 2018

Minimum Information about an Uncultivated Virus Genome (MIUViG).

Nat Biotechnol 2018 Dec 17. Epub 2018 Dec 17.

US Department of Energy Joint Genome Institute, Walnut Creek, California, USA.

We present an extension of the Minimum Information about any (x) Sequence (MIxS) standard for reporting sequences of uncultivated virus genomes. Minimum Information about an Uncultivated Virus Genome (MIUViG) standards were developed within the Genomic Standards Consortium framework and include virus origin, genome quality, genome annotation, taxonomic classification, biogeographic distribution and in silico host prediction. Community-wide adoption of MIUViG standards, which complement the Minimum Information about a Single Amplified Genome (MISAG) and Metagenome-Assembled Genome (MIMAG) standards for uncultivated bacteria and archaea, will improve the reporting of uncultivated virus genomes in public databases. Read More

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December 2018
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Preventing intergenerational trauma transmission: A critical interpretive synthesis.

J Clin Nurs 2018 Dec 16. Epub 2018 Dec 16.

Australian Catholic University & NorthWestern Mental Health, Melbourne Health.

Aim: To synthesise and critically interpret literature of relevance to intervening in intergenerational transmission of relational trauma within parent-infant relationships.

Background: Intergenerational trauma is a discrete process and form of psychological trauma transmitted within families and communities. Intergenerational trauma can be transmitted through attachment relationships where the parent has experienced relational trauma and have significant impacts upon individuals across the lifespan, including predisposition to further trauma. Read More

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December 2018

A case-control genome wide association study of substance use disorder (SUD) identifies novel variants on chromosome 7p14.1 in patients from the United Arab Emirates (UAE).

Am J Med Genet B Neuropsychiatr Genet 2018 Dec 16. Epub 2018 Dec 16.

School of Psychiatry and Clinical Neurosciences, The University of Western Australia, Crawley, Western Australia, Australia.

Genome wide association studies (GWASs) have provided insights into the molecular basis of the disorder in different population. This study presents the first GWAS of substance use disorder (SUD) in patients from the United Arab Emirates (UAE). The aim was to identify genetic association(s) that may provide insights into the molecular basis of the disorder. Read More

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December 2018

Temperature thresholds for germination in 20 short-range endemic plant species from a Greenstone Belt in southern Western Australia.

Authors:
A Cochrane

Plant Biol (Stuttg) 2018 Dec 17. Epub 2018 Dec 17.

Biodiversity Conservation Science, Department of Biodiversity, Conservation and Attractions Bentley Delivery Centre, Locked Bag 104, Western Australia, 6983.

The study of climate-driven effects on seed traits such as germination has gained momentum over the past decade as the impact of global warming becomes more apparent on the health and survival of plant diversity. Seed response to warming was evaluated in a suite of short-range endemic species from the biodiverse Greenstone Belt of southern Western Australia. The temperature dimensions for germination in 20 woody perennials were identified using small un-replicated samples over 6 weeks on a temperature gradient plate (constant and fluctuating temperatures between 5 and 40 °C). Read More

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December 2018

The burden of hospitalized sports-related injuries in children: an Australian population-based study, 2005-2013.

Inj Epidemiol 2018 Dec 17;5(1):45. Epub 2018 Dec 17.

Child Population and Translational Health Research, The Children's Hospital at Westmead Clinical School, Level 2 The Hub, Charles Perkins Centre D17, The University of Sydney, Westmead, NSW, 2006, Australia.

Background: There is concern about recent increase and severity of sports-related injuries in children. Despite the benefits of sports participation, injuries may carry long-term health consequences. We aimed to evaluate the prevalence, characteristics and types of hospitalized sports-related injuries in children. Read More

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December 2018

Facile Tuning of the Surface Energy of Cellulose Nanofibers for Nanocomposite Reinforcement.

ACS Omega 2018 Nov 27;3(11):15933-15942. Epub 2018 Nov 27.

Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane 4072, Queensland, Australia.

The isolation of nanocellulose from lignocellulosic biomass, with desirable surface chemistry and morphology, has gained extensive scientific attention for various applications including polymer nanocomposite reinforcement. Additionally, environmental and economic concerns have driven researchers to explore viable alternatives to current isolation approaches, employing chemicals with reduced environmental impact. To address these issues, in this study, we have tuned the amphiphilic behavior of cellulose nanofibers (CNFs) by employing controlled alkali treatment, instead of in combination with expensive, environmentally unsustainable conventional approaches. Read More

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November 2018

In situ recombination junction between p-Si and TiO enables high-efficiency monolithic perovskite/Si tandem cells.

Sci Adv 2018 Dec 14;4(12):eaau9711. Epub 2018 Dec 14.

Centre for Sustainable Energy Systems, Research School of Engineering, The Australian National University, Canberra 2601, Australia.

Increasing the power conversion efficiency of silicon (Si) photovoltaics is a key enabler for continued reductions in the cost of solar electricity. Here, we describe a two-terminal perovskite/Si tandem design that increases the Si cell's output in the simplest possible manner: by placing a perovskite cell directly on top of the Si bottom cell. The advantageous omission of a conventional interlayer eliminates both optical losses and processing steps and is enabled by the low contact resistivity attainable between n-type TiO and Si, established here using atomic layer deposition. Read More

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December 2018

Classification challenges in the field of eating disorders: can severe and enduring anorexia nervosa be better defined?

J Eat Disord 2018 10;6:41. Epub 2018 Dec 10.

2School of Psychology, The University of Sydney, Sydney, Australia.

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December 2018

[Cu]CuCl PET imaging reveals activity of Dextran-Catechin on tumor copper homeostasis.

Theranostics 2018 9;8(20):5645-5659. Epub 2018 Nov 9.

Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, NSW, Australia 2031.

Given the strong clinical evidence that copper levels are significantly elevated in a wide spectrum of tumors, copper homeostasis is considered as an emerging target for anticancer drug design. Monitoring copper levels is therefore of paramount importance when assessing the efficacy of copper-targeting drugs. Herein, we investigated the activity of the copper-targeting compound Dextran-Catechin by developing a [Cu]CuCl PET imaging protocol to monitor its effect on copper homeostasis in tumors. Read More

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November 2018

Imaging Individual Differences in the Response of the Human Suprachiasmatic Area to Light.

Front Neurol 2018 29;9:1022. Epub 2018 Nov 29.

Monash Institute of Cognitive and Clinical Neurosciences and School of Psychological Sciences, Monash University, Melbourne, VIC, Australia.

Circadian disruption is associated with poor health outcomes, including sleep and mood disorders. The suprachiasmatic nucleus (SCN) of the anterior hypothalamus acts as the master biological clock in mammals, regulating circadian rhythms throughout the body. The clock is synchronized to the day/night cycle via retinal light exposure. Read More

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November 2018
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Contemporary Knowledge Workers and the Boundaryless Work-Life Interface: Implications for the Human Resource Management of the Knowledge Workforce.

Front Psychol 2018 30;9:2414. Epub 2018 Nov 30.

School of Management, College of Business, RMIT University, Melbourne, VIC, Australia.

In the last decade, knowledge workers have seen tremendous change in ways of working and living, driven by proliferating mobile communication technologies, the rise of dual-income couples, shifting expectations of ideal motherhood and involved fatherhood, and the rise of flexible working arrangements. Drawing on 54 interviews with Australian knowledge workers in the information technology sector, we argue that the interface between work and life is now blurred and boundaryless for knowledge workers. By this, we mean that knowledge workers are empowered and enslaved by mobile devices that bring work into the home, and family into the workplace. Read More

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November 2018

Assessment of pain-related fear in individuals with chronic painful conditions.

J Pain Res 2018 30;11:3071-3077. Epub 2018 Nov 30.

Australian Research Centre for Population Oral Health, Adelaide Dental School, The University of Adelaide, Adelaide, SA, Australia,

Background: Heightened fear and anxiety related to pain may result in emotional and behavioral avoidance responses causing disability, distress, and depression. Fear and anxiety associated with pain can potentially change the course of the pain experience. It is plausible that fear and anxiety related to pain affect the duration and frequency of pain experienced by the patient. Read More

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November 2018

Feeding strategies for the acquisition of high-quality food sources in stream macroinvertebrates: Collecting, integrating, and mixed feeding.

Limnol Oceanogr 2018 Sep 6;63(5):1964-1978. Epub 2018 May 6.

WasserCluster Lunz-Inter-University Centre for Aquatic Ecosystem Research Lunz am See Austria.

Aquatic macroinvertebrates play an important functional role in energy transfer in food webs, linking basal food sources to upper trophic levels that include fish, birds, and humans. However, the trophic coupling of nutritional quality between macroinvertebrates and their food sources is still poorly understood. We conducted a field study in subalpine streams in Austria to investigate how the nutritional quality (measured by long-chain polyunsaturated fatty acids, LC-PUFAs) in macroinvertebrates changes relative to their basal food sources. Read More

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September 2018

Predictors of E-cigarette Use Among Young Australian Women.

Am J Prev Med 2018 Dec 13. Epub 2018 Dec 13.

Research Centre for Generational Health and Ageing, Faculty of Health and Medicine, University of Newcastle, Newcastle, Australia.

Introduction: E-cigarette use is controversial worldwide. The majority of previous studies on e-cigarette use were not gender specific. This study aimed to identify the predictors of e-cigarette use among young Australian women. Read More

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December 2018

'A match made in midwifery': Women's perceptions of student midwife partnerships.

Women Birth 2018 Dec 13. Epub 2018 Dec 13.

Southern Cross University, School of Health and Human Sciences, Australia.

Problem: Little is known regarding experiences of childbearing women participating in a Continuity of Care Experience.

Background: Continuity of Care immersion is considered a vital component of undergraduate education in Australia. A student midwife follows a woman's childbearing journey regardless of the woman's individual needs or chosen model of care. Read More

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December 2018

A National Wastewater Monitoring Program for a better understanding of public health: A case study using the Australian Census.

Environ Int 2018 Dec 14. Epub 2018 Dec 14.

Queensland Alliance for Environmental Health Sciences, The University of Queensland, Woolloongabba, Queensland 4102, Australia.

Wastewater contains a large range of biological and chemical markers of human activity and exposures. Through systematic collection and analysis of these markers within wastewater samples it is possible to measure the public health of whole populations. The analysis of effluent and biosolids can also be used to understand the release of chemicals from wastewater treatment plants into the environment. Read More

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December 2018

Effect of point-of-care C-reactive protein testing on antibiotic prescription in febrile patients attending primary care in Thailand and Myanmar: an open-label, randomised, controlled trial.

Lancet Glob Health 2019 Jan;7(1):e119-e131

Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK. Electronic address:

Background: In southeast Asia, antibiotic prescription in febrile patients attending primary care is common, and a probable contributor to the high burden of antimicrobial resistance. The objective of this trial was to explore whether C-reactive protein (CRP) testing at point of care could rationalise antibiotic prescription in primary care, comparing two proposed thresholds to classify CRP concentrations as low or high to guide antibiotic treatment.

Methods: We did a multicentre, open-label, randomised, controlled trial in participants aged at least 1 year with a documented fever or a chief complaint of fever (regardless of previous antibiotic intake and comorbidities other than malignancies) recruited from six public primary care units in Thailand and three primary care clinics and one outpatient department in Myanmar. Read More

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January 2019

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes.

Authors:
Nasim Mavaddat Kyriaki Michailidou Joe Dennis Michael Lush Laura Fachal Andrew Lee Jonathan P Tyrer Ting-Huei Chen Qin Wang Manjeet K Bolla Xin Yang Muriel A Adank Thomas Ahearn Kristiina Aittomäki Jamie Allen Irene L Andrulis Hoda Anton-Culver Natalia N Antonenkova Volker Arndt Kristan J Aronson Paul L Auer Päivi Auvinen Myrto Barrdahl Laura E Beane Freeman Matthias W Beckmann Sabine Behrens Javier Benitez Marina Bermisheva Leslie Bernstein Carl Blomqvist Natalia V Bogdanova Stig E Bojesen Bernardo Bonanni Anne-Lise Børresen-Dale Hiltrud Brauch Michael Bremer Hermann Brenner Adam Brentnall Ian W Brock Angela Brooks-Wilson Sara Y Brucker Thomas Brüning Barbara Burwinkel Daniele Campa Brian D Carter Jose E Castelao Stephen J Chanock Rowan Chlebowski Hans Christiansen Christine L Clarke J Margriet Collée Emilie Cordina-Duverger Sten Cornelissen Fergus J Couch Angela Cox Simon S Cross Kamila Czene Mary B Daly Peter Devilee Thilo Dörk Isabel Dos-Santos-Silva Martine Dumont Lorraine Durcan Miriam Dwek Diana M Eccles Arif B Ekici A Heather Eliassen Carolina Ellberg Christoph Engel Mikael Eriksson D Gareth Evans Peter A Fasching Jonine Figueroa Olivia Fletcher Henrik Flyger Asta Försti Lin Fritschi Marike Gabrielson Manuela Gago-Dominguez Susan M Gapstur José A García-Sáenz Mia M Gaudet Vassilios Georgoulias Graham G Giles Irina R Gilyazova Gord Glendon Mark S Goldberg David E Goldgar Anna González-Neira Grethe I Grenaker Alnæs Mervi Grip Jacek Gronwald Anne Grundy Pascal Guénel Lothar Haeberle Eric Hahnen Christopher A Haiman Niclas Håkansson Ute Hamann Susan E Hankinson Elaine F Harkness Steven N Hart Wei He Alexander Hein Jane Heyworth Peter Hillemanns Antoinette Hollestelle Maartje J Hooning Robert N Hoover John L Hopper Anthony Howell Guanmengqian Huang Keith Humphreys David J Hunter Milena Jakimovska Anna Jakubowska Wolfgang Janni Esther M John Nichola Johnson Michael E Jones Arja Jukkola-Vuorinen Audrey Jung Rudolf Kaaks Katarzyna Kaczmarek Vesa Kataja Renske Keeman Michael J Kerin Elza Khusnutdinova Johanna I Kiiski Julia A Knight Yon-Dschun Ko Veli-Matti Kosma Stella Koutros Vessela N Kristensen Ute Krüger Tabea Kühl Diether Lambrechts Loic Le Marchand Eunjung Lee Flavio Lejbkowicz Jenna Lilyquist Annika Lindblom Sara Lindström Jolanta Lissowska Wing-Yee Lo Sibylle Loibl Jirong Long Jan Lubiński Michael P Lux Robert J MacInnis Tom Maishman Enes Makalic Ivana Maleva Kostovska Arto Mannermaa Siranoush Manoukian Sara Margolin John W M Martens Maria Elena Martinez Dimitrios Mavroudis Catriona McLean Alfons Meindl Usha Menon Pooja Middha Nicola Miller Fernando Moreno Anna Marie Mulligan Claire Mulot Victor M Muñoz-Garzon Susan L Neuhausen Heli Nevanlinna Patrick Neven William G Newman Sune F Nielsen Børge G Nordestgaard Aaron Norman Kenneth Offit Janet E Olson Håkan Olsson Nick Orr V Shane Pankratz Tjoung-Won Park-Simon Jose I A Perez Clara Pérez-Barrios Paolo Peterlongo Julian Peto Mila Pinchev Dijana Plaseska-Karanfilska Eric C Polley Ross Prentice Nadege Presneau Darya Prokofyeva Kristen Purrington Katri Pylkäs Brigitte Rack Paolo Radice Rohini Rau-Murthy Gad Rennert Hedy S Rennert Valerie Rhenius Mark Robson Atocha Romero Kathryn J Ruddy Matthias Ruebner Emmanouil Saloustros Dale P Sandler Elinor J Sawyer Daniel F Schmidt Rita K Schmutzler Andreas Schneeweiss Minouk J Schoemaker Fredrick Schumacher Peter Schürmann Lukas Schwentner Christopher Scott Rodney J Scott Caroline Seynaeve Mitul Shah Mark E Sherman Martha J Shrubsole Xiao-Ou Shu Susan Slager Ann Smeets Christof Sohn Penny Soucy Melissa C Southey John J Spinelli Christa Stegmaier Jennifer Stone Anthony J Swerdlow Rulla M Tamimi William J Tapper Jack A Taylor Mary Beth Terry Kathrin Thöne Rob A E M Tollenaar Ian Tomlinson Thérèse Truong Maria Tzardi Hans-Ulrich Ulmer Michael Untch Celine M Vachon Elke M van Veen Joseph Vijai Clarice R Weinberg Camilla Wendt Alice S Whittemore Hans Wildiers Walter Willett Robert Winqvist Alicja Wolk Xiaohong R Yang Drakoulis Yannoukakos Yan Zhang Wei Zheng Argyrios Ziogas Alison M Dunning Deborah J Thompson Georgia Chenevix-Trench Jenny Chang-Claude Marjanka K Schmidt Per Hall Roger L Milne Paul D P Pharoah Antonis C Antoniou Nilanjan Chatterjee Peter Kraft Montserrat García-Closas Jacques Simard Douglas F Easton

Am J Hum Genet 2018 Dec 5. Epub 2018 Dec 5.

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK.

Stratification of women according to their risk of breast cancer based on polygenic risk scores (PRSs) could improve screening and prevention strategies. Our aim was to develop PRSs, optimized for prediction of estrogen receptor (ER)-specific disease, from the largest available genome-wide association dataset and to empirically validate the PRSs in prospective studies. The development dataset comprised 94,075 case subjects and 75,017 control subjects of European ancestry from 69 studies, divided into training and validation sets. Read More

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December 2018
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The behaviour change techniques used by Australian physiotherapists to promote non-treatment physical activity to patients with musculoskeletal conditions.

J Sci Med Sport 2019 Jan 9;22(1):2-10. Epub 2018 Jun 9.

School of Medical and Health Sciences, Edith Cowan University, Australia.

Objectives: To determine: (i) the behaviour change techniques used by a sample of Australian physiotherapists to promote non-treatment physical activity; and (ii) whether those behaviour change techniques are different to the techniques used to encourage adherence to rehabilitation exercises.

Design: Cross-sectional survey.

Method: An online self-report survey was advertised to private practice and outpatient physiotherapists treating patients with musculoskeletal conditions. Read More

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January 2019

Wearing compression socks during exercise aids subsequent performance.

J Sci Med Sport 2019 Jan 19;22(1):123-127. Epub 2018 Jun 19.

Physiology, Australian Institute of Sport, Australia; Sport Performance Optimisation Research Team (SPORT), University of Tasmania, Australia.

Objectives: To assess the effect of wearing compression socks on immediate and subsequent 5km running time trials, with particular attention to the influences on physiological, perceptual and performance-based parameters.

Design: Counter-balanced cross-over experiment.

Methods: Twelve male runners (mean±SD 5km run time 19:29±1:18min:s) each completed two experimental sessions. Read More

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January 2019

Catheter Ablation of Idiopathic Ventricular Arrhythmias.

Heart Lung Circ 2019 Jan 17;28(1):102-109. Epub 2018 Oct 17.

Cardiovascular Division, Electrophysiology Section, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

Ventricular arrhythmias (VA) are observed in the setting of structural heart disease. However, in a proportion of patients presenting with VT, the routine diagnostic modalities fail to demonstrate overt myocardial abnormality. These arrhythmias have been called idiopathic VAs. Read More

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January 2019

Retrospective analysis of pleural effusion in cats.

J Feline Med Surg 2018 Dec 17:1098612X18816489. Epub 2018 Dec 17.

1 Clinic of Small Animal Medicine, LMU University of Munich, Munich, Germany.

Objectives: Pleural effusion is a common presenting cause for feline patients in small animal practice. The objectives of this study were to identify possible correlations between the aetiology of effusion and clinical and laboratory findings.

Methods: In this retrospective study of 306 cats diagnosed with pleural effusion of established aetiology, cats were divided into six major groups: cardiac disease (CD), feline infectious peritonitis (FIP), neoplasia, pyothorax, chylothorax and miscellaneous. Read More

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December 2018

Trials with proxy-reported outcomes registered on the Australian New Zealand Clinical Trials Registry (ANZCTR).

Qual Life Res 2018 Dec 15. Epub 2018 Dec 15.

Department of Health Services, Policy & Practice, Brown University School of Public Health, Providence, USA.

Aims: A proxy is someone other than a patient who reports a patient's outcomes as if they are the patient. Due to known discordance with patient reports, proxies are often not recommended in clinical trials; however, proxies may be needed in certain research contexts. We aimed to identify and describe trials registered on the Australian New Zealand Clinical Trials Registry (ANZCTR) with proxy-reported endpoints. Read More

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December 2018

Epidemiology of gastrostomy insertion for children and adolescents with intellectual disability.

Eur J Pediatr 2018 Dec 15. Epub 2018 Dec 15.

Telethon Kids Institute, Centre for Child Health Research, The University of Western Australia, PO Box 855, West Perth, Western Australia, 6872, Australia.

The largest group of recipients of pediatric gastrostomy have neurological impairment with intellectual disability (ID). This study investigated trends in first gastrostomy insertion according to markers of disadvantage and ID etiology. Linked administrative and health data collected over a 32-year study period (1983-2014) for children with ID born between 1983 and 2009 in Western Australia were examined. Read More

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December 2018

No association between common genetic variation in FOXP2 and language impairment in schizophrenia.

Psychiatry Res 2018 Dec 6;271:590-597. Epub 2018 Dec 6.

Division of Psychiatry, Centre for Clinical Research in Neuropsychiatry, Faculty of Health and Medical Sciences, The University of Western Australia, Medical Research Foundation Building, Perth WA 6000, Australia; Perth Voices Clinic, South Street, Murdoch, WA 6150, Australia. Electronic address:

The FOXP2 gene is hypothesised to be involved in schizophrenia by affecting speech and language development. Associations between common single nucleotide polymorphisms (SNPs) in FOXP2 and language have been inconsistent. We tested five previously associated SNPs for association with language in the Western Australian Family Study of Schizophrenia (n = 709, including n = 333 with schizophrenia/spectrum disorder) and found no significant associations. Read More

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December 2018

DNA based method for determining source country of the short beaked echidna (Tachyglossus aculeatus) in the illegal wildlife trade.

Forensic Sci Int 2018 Dec 5;295:46-53. Epub 2018 Dec 5.

Australian Centre for Wildlife Genomics, Australian Museum Research Institute, 1 William Street, Sydney, Australia. Electronic address:

The illegal trade in wild animals being sold as 'captive bred' is an emerging issue in the pet and zoo industry and has both animal welfare and conservation implications. DNA based methods can be a quick, inexpensive, and definitive way to determine the source of these animals, thereby assisting efforts to combat this trade. The short beaked echidna (Tachyglossus aculeatus) is currently one of the species suspected to be targeted in this trade. Read More

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December 2018

Incremental clinical effectiveness and cost effectiveness of providing supervised physiotherapy in addition to usual medical care in patients with osteoarthritis of the hip or knee: 2-year results of the MOA randomised controlled trial.

Osteoarthritis Cartilage 2018 Dec 13. Epub 2018 Dec 13.

Department of Physical Therapy, High Point University, High Point, North Carolina, USA. Electronic address:

Objective: To investigate the clinical- and cost-effectiveness at 2-year follow-up of providing individual, supervised exercise physiotherapy and/or manual physiotherapy in addition to usual medical care.

Method: People with hip or knee osteoarthritis meeting the American College of Rheumatology clinical diagnostic criteria were randomised (1:1, concealed, assessor-blinded) to 4 groups: usual medical care; supervised exercise physiotherapy; manual physiotherapy; or combined exercise and manual physiotherapy. Physiotherapy group participants were provided 10 50-minute treatment sessions including booster sessions at 4 and 13 months, in addition to usual care. Read More

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December 2018

Plio-Pleistocene diversification and biogeographic barriers in southern Australia reflected in the phylogeography of a widespread and common lizard species.

Mol Phylogenet Evol 2018 Dec 13. Epub 2018 Dec 13.

College of Science and Engineering, Flinders University, South Australia; Evolutionary Biology Unit, South Australian Museum.

Palaeoclimatic events and biogeographical processes since the mid-Tertiary have played an important role in shaping the evolution and distribution of Australian fauna. However, their impacts on fauna in southern and arid zone regions of Australia are not well understood. Here we investigate the phylogeography of an Australian scincid lizard, Tiliqua rugosa, across southern Australia using mitochondrial DNA (mtDNA) and 11 nuclear DNA markers (nuDNA), including nine anonymous nuclear loci. Read More

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December 2018

Renewing the performance of an expired particle packed column using active flow technology end fittings.

J Chromatogr A 2018 Dec 4. Epub 2018 Dec 4.

Australian Centre for Research on Separation Science (ACROSS), School of Science and Health, Western Sydney University, North Paramatta, NSW, 2050, Australia. Electronic address:

The performance of a particle packed column will inevitably degrade through use or misadventure. 'Active flow technology' (AFT) is known to greatly improve the performance of pristine columns, but is as of yet untested when used on columns that have degraded significantly. In this study AFT was used to regenerate a degraded column, where the reduced plate height and asymmetry values were 3. Read More

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December 2018

Calculating the economic burden of fatal drowning in Australia.

J Safety Res 2018 Dec 21;67:57-63. Epub 2018 Sep 21.

Royal Life Saving Society - Australia, Broadway, NSW, Australia.

Background: Aquatic activities provide physical and social benefits, while the risk of drowning generates countervailing social costs. Drawing on estimates of fatal drowning gathered by Royal Life Saving Society - Australia, this paper outlines a method for estimating the economic burden attributable to fatal drowning.

Methods: This study estimated the burden of fatal drowning by combining Value of a Statistical Life Year (VSLY), hospitalization, productivity and emergency services costs. Read More

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December 2018

Preparation of hydroxylated lecithin complexed iodine/carboxymethyl chitosan/sodium alginate composite membrane by microwave drying and its applications in infected burn wound treatment.

Carbohydr Polym 2019 Feb 29;206:435-445. Epub 2018 Oct 29.

Agriculture Products Processing Research Institute, Chinese Academy of Tropical Agricultural Sciences, Zhanjiang, 524001, PR China.

Improving the antibacterial properties of membrane wound dressings of natural polymers is crucial. Iodine is an important safe inorganic antibacterial agent, but was confined in the composition with polymer membranes due to the challenges of homogeneity and stability during drying. In the present work, iodine was complexed with hydroxylated lecithin (HL) to improve its stability and complexing efficiency for the composition with carboxymethly chitosan/sodium alginate. Read More

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February 2019

The structure and stability of the disulfide-linked γS-crystallin dimer provide insight into oxidation products associated with lens cataract formation.

J Mol Biol 2018 Dec 12. Epub 2018 Dec 12.

Research School of Chemistry, The Australian National University, Acton, ACT, 2601, Australia. Electronic address:

The reducing environment in the eye lens diminishes with age, leading to significant oxidative stress. Oxidation of lens crystallin proteins is the major contributor to their destabilization and deleterious aggregation that scatters visible light, obscures vision and ultimately leads to cataracts. However, the molecular basis for oxidation-induced aggregation is unknown. Read More

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December 2018
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Effectiveness of a theory-based sun-safe randomised behavioural change trial among Australian adolescents.

Psychooncology 2018 Dec 15. Epub 2018 Dec 15.

Australian Institute for Suicide Research and Prevention, Griffith University, Mt Gravatt, Queensland.

Objective: Sun safety is crucial for preventing skin cancer. This study evaluated a school-based intervention based on the Theory of Planned Behaviour (TPB) which aimed to encourage sun-protective behaviour among adolescents.

Methods: Secondary school students (N=382; 61. Read More

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December 2018
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Scutellarein inhibits RANKL-induced osteoclast formation in vitro and prevents LPS-induced bone loss in vivo.

J Cell Physiol 2018 Dec 14. Epub 2018 Dec 14.

Department of Trauma Orthopedic and Hand Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.

Osteoporosis, arthritis, Peget's disease, bone tumor, periprosthetic joint infection, and periprosthetic loosening have a common characteristic of osteolysis, which is characterized by the enhanced osteoclastic bone resorptive function. At present, the treatment target of these diseases is to interfere with osteoclastic formation and function. Scutellarein (Scu), a flavonoids compound, can inhibit the progress of tumor and inflammation. Read More

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December 2018

Flow-Mediated Drug Transport from Drug-Eluting Stents is Negligible: Numerical and In-vitro Investigations.

Ann Biomed Eng 2018 Dec 14. Epub 2018 Dec 14.

UNSW Sydney, Sydney, NSW, Australia.

Prior numerical studies have shown that the blood flow patterns surrounding drug-eluting stents can enhance drug uptake in stented arteries. However, these studies employed steady-state simulations, wherein flow and drug transport parameters remained constant with respect to time. In the present study, numerical simulations and in-vitro experiments were performed to determine whether luminal blood flow patterns can truly enhance drug uptake in stented arteries. Read More

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December 2018

Characterizing coral skeleton mineralogy with Raman spectroscopy.

Authors:
Thomas M DeCarlo

Nat Commun 2018 Dec 14;9(1):5325. Epub 2018 Dec 14.

School of Earth Sciences and Oceans Graduate School, The University of Western Australia, 35 Stirling Highway, Crawley, WA, 6009, Australia.

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December 2018

Definition of whole person care in general practice in the English language literature: a systematic review.

BMJ Open 2018 Dec 14;8(12):e023758. Epub 2018 Dec 14.

Psycho-Oncology Co-operative Research Group, Sydney Health Ethics, Faculty of Medicine, University of Sydney, Sydney, New South Wales, Australia.

Objectives: The importance of 'whole person' or 'holistic' care is widely recognised, particularly with an increasing prevalence of chronic multimorbidity internationally. This approach to care is a defining feature of general practice. However, its precise meaning remains ambiguous. Read More

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December 2018

Predicting 7-year mortality for use with evidence-based guidelines for Prostate-Specific Antigen (PSA) testing: findings from a large prospective study of 123 697 Australian men.

BMJ Open 2018 Dec 14;8(12):e022613. Epub 2018 Dec 14.

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.

Objectives: To develop and validate a prediction model for short-term mortality in Australian men aged ≥45years, using age and self-reported health variables, for use when implementing the Australian Clinical Practice Guidelines for Prostate-Specific Antigen (PSA) Testing and Early Management of Test-Detected Prostate Cancer. Implementation of one of the Guideline recommendations requires an estimate of 7-year mortality.

Design: Prospective cohort study using questionnaire data linked to mortality data. Read More

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December 2018

haplotypes confer different sulfite tolerance when expressed in a null mutant.

Appl Environ Microbiol 2018 Dec 14. Epub 2018 Dec 14.

The Australian Wine Research Institute, PO Box 197, Glen Osmond, Adelaide, South Australia, 5064, Australia.

SO addition is practiced in the wine industry to mitigate the risk of microbial spoilage and to extend wine shelf-life. Generally, this strategy does not interfere with primary alcoholic fermentation as wine strains of exhibit significant SO tolerance, largely driven by the efflux pump Ssu1p. One of the key yeast species responsible for wine spoilage is , which also exhibits strain-dependent SO tolerance, although this occurs via unknown mechanisms. Read More

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December 2018
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Phase IIa, placebo-controlled, randomised study of lutikizumab, an anti-interleukin-1α and anti-interleukin-1β dual variable domain immunoglobulin, in patients with erosive hand osteoarthritis.

Ann Rheum Dis 2018 Dec 14. Epub 2018 Dec 14.

Immunology Development, AbbVie, North Chicago, Illinois, USA.

Objective: To assess the efficacy, safety, pharmacokinetics and pharmacodynamics of the anti-interleukin (IL)-1α/β dual variable domain immunoglobulin lutikizumab (ABT-981) in erosive hand osteoarthritis (HOA).

Methods: Patients with ≥1 erosive and ≥3 tender and/or swollen hand joints were randomised to placebo or lutikizumab 200 mg subcutaneously every 2 weeks for 24 weeks. The primary endpoint was change in Australian/Canadian Osteoarthritis Hand Index (AUSCAN) pain subdomain score from baseline to 16 weeks. Read More

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December 2018

Pipeline shield with single antiplatelet therapy in aneurysmal subarachnoid haemorrhage: multicentre experience.

J Neurointerv Surg 2018 Dec 14. Epub 2018 Dec 14.

Institute of Neurological Sciences, Prince of Wales Hospital, Randwick, New South Wales, Australia.

Background: The Pipeline Embolisation Device with Shield technology (PED-Shield) is suggested to have reduced thrombogenicity. This reduced thrombogenicity may make it possible to use safely in the acute treatment of aneurysmal subarachnoid haemorrhage (aSAH) on single antiplatelet therapy (SAPT).

Objective: To evaluate the safety and efficacy of the off-label use of PED-Shield with SAPT for the acute treatment of aSAH. Read More

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December 2018