122,020 results match your criteria Australian Journal Of Linguistics[Journal]


The cost of Hypertensive Disorders of Pregnancy to the Australian healthcare system.

Pregnancy Hypertens 2020 Jul 1;21:197-199. Epub 2020 Jul 1.

School of Nursing and Midwifery, Griffith University, Queensland, Australia.

In Australia, Hypertensive Disorders of Pregnancy are one of the leading causes of maternal death. Additionally, mothers and babies can experience significant morbidity associated with Hypertensive Disorders of Pregnancy. Currently, there is little understanding about the resources spent on this pregnancy complication in Australia. Read More

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http://dx.doi.org/10.1016/j.preghy.2020.06.007DOI Listing

Taxonomic determination of the cryptogenic red alga, Chondria tumulosa sp. nov., (Rhodomelaceae, Rhodophyta) from Papahānaumokuākea Marine National Monument, Hawai'i, USA: A new species displaying invasive characteristics.

PLoS One 2020 7;15(7):e0234358. Epub 2020 Jul 7.

Department of Biology, College of Charleston, Charleston, SC, United States of America.

Survey cruises by the National Oceanic and Atmospheric Administration (NOAA) in 2016 and 2019 yielded specimens of an undetermined red alga that rapidly attained alarming levels of benthic coverage at Pearl and Hermes Atoll, Papahānaumokuākea Marine National Monument, Hawai'i. By 2019 the seaweed had covered large expanses on the northeast side of the atoll with mat-like, extensive growth of entangled thalli. Specimens were analyzed using light microscopy and molecular analysis, and were compared to morphological descriptions in the literature for closely related taxa. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0234358PLOS

Principles for creating a single authoritative list of the world's species.

PLoS Biol 2020 Jul 7;18(7):e3000736. Epub 2020 Jul 7.

Taxonomy Australia, Australian Academy of Science, Canberra, Australia.

Lists of species underpin many fields of human endeavour, but there are currently no universally accepted principles for deciding which biological species should be accepted when there are alternative taxonomic treatments (and, by extension, which scientific names should be applied to those species). As improvements in information technology make it easier to communicate, access, and aggregate biodiversity information, there is a need for a framework that helps taxonomists and the users of taxonomy decide which taxa and names should be used by society whilst continuing to encourage taxonomic research that leads to new species discoveries, new knowledge of species relationships, and the refinement of existing species concepts. Here, we present 10 principles that can underpin such a governance framework, namely (i) the species list must be based on science and free from nontaxonomic considerations and interference, (ii) governance of the species list must aim for community support and use, (iii) all decisions about list composition must be transparent, (iv) the governance of validated lists of species is separate from the governance of the names of taxa, (v) governance of lists of accepted species must not constrain academic freedom, (vi) the set of criteria considered sufficient to recognise species boundaries may appropriately vary between different taxonomic groups but should be consistent when possible, (vii) a global list must balance conflicting needs for currency and stability by having archived versions, (viii) contributors need appropriate recognition, (ix) list content should be traceable, and (x) a global listing process needs both to encompass global diversity and to accommodate local knowledge of that diversity. Read More

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http://dx.doi.org/10.1371/journal.pbio.3000736DOI Listing

Endocardial-Epicardial Phase Mapping of Prolonged Persistent Atrial Fibrillation Recordings: High Prevalence of Dissociated Activation Patterns.

Circ Arrhythm Electrophysiol 2020 Jul 7. Epub 2020 Jul 7.

Department of Cardiology, Royal Melbourne Hospital & Department of Medicine, University of Melbourne, Melbourne, Australia.

- Endocardial-epicardial dissociation (EED) and focal breakthroughs in humans with atrial fibrillation (AF) have been recently demonstrated using activation mapping of short 10-second AF segments. In the current study we used simultaneous endo-epi phase mapping to characterise endo-epi activation patterns on long segments of human persistent AF (PeAF). - Simultaneous intra-operative mapping of endo- and epicardial lateral RA wall was performed in patients with PeAF using two high-density grid catheters (16 electrodes, 3mm spacing). Read More

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http://dx.doi.org/10.1161/CIRCEP.120.008512DOI Listing

Maternity iron, anaemia and blood management in South Australia: a practice-based evidence for clinical practice improvement.

Vox Sang 2020 Jul 7. Epub 2020 Jul 7.

Lyell McEwin Hospital, Northern Adelaide Local Health Network, Elizabeth Vale, SA, Australia.

Background: Anaemia at delivery is a strong modifiable risk factor for transfusion in women with a postpartum haemorrhage (PPH). A Maternity Patient Blood Management (PBM) Practice Based Evidence Clinical Practice Improvement (CPI) was conducted to optimize antenatal haemoglobin and iron stores prior to delivery.

Methods: Australian maternity PBM CPI resources (featuring algorithms on diagnosing iron deficiency with both haemoglobin and ferritin screening, as well as information on oral iron therapy for maternity patients) were introduced at a major tertiary hospital from November 2016 to March 2017. Read More

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http://dx.doi.org/10.1111/vox.12969DOI Listing

Ecklonia radiata extract containing eckol protects neuronal cells against Aβ evoked toxicity and reduces aggregate density.

Food Funct 2020 Jul 7. Epub 2020 Jul 7.

Discipline of Pharmacology, Adelaide Medical School, Faculty of Health Sciences, The University of Adelaide, Adelaide, South Australia, Australia.

Brown seaweed (Phaeophyceae) polyphenolics such as phlorotannins are ascribed various biological activities, including neuroprotection. Of these seaweeds, Ecklonia radiata (E. radiata) is found abundantly along South Australian coastal regions; however it has not been explored for various biological activities relative to any component phlorotannins previously ascribed neuroprotective capacity. Read More

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http://dx.doi.org/10.1039/d0fo01438aDOI Listing

Gender differences in social harms from drinking among young Australians: findings from the Mater University Study of Pregnancy and its Outcomes.

J Addict Dis 2020 Jul 7:1-13. Epub 2020 Jul 7.

Institute for Social Science Research, University of Queensland, Brisbane, Australia.

Background: Despite the growing interest in investigating social harms from drinking, little is known about drinkers' reports of these harms and their gender differences among Australian young adults at age 30. We aimed to examine gender differences of social harms from drinking as reported by drinkers.

Methods: 2,200 young adults at age 30 with complete data on social harms from drinking were drawn from the 30-year follow-up of the Mater-University of Queensland Study of Pregnancy. Read More

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http://dx.doi.org/10.1080/10550887.2020.1767324DOI Listing

The Mental Health of Online Learners within the Educational Sector.

Issues Ment Health Nurs 2020 Jul 7:1-3. Epub 2020 Jul 7.

School of Health Sciences, College of Health and Medicine, University of Tasmania, Sydney, NSW, Australia.

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http://dx.doi.org/10.1080/01612840.2020.1776552DOI Listing

Trends and characteristics in barbiturate deaths Australia 2000-2019: a national retrospective study.

Clin Toxicol (Phila) 2020 Jul 7:1-7. Epub 2020 Jul 7.

National Drug and Alcohol Research Centre, UNSW Sydney, Sydney, Australia.

Introduction: There have been increasing reports documenting barbiturate-related deaths, despite routine prescribing for only relatively rare indications. The aims of the current study were to examine trends in barbiturate-related deaths in Australia from 2000 to 2019 and determine the case characteristics and circumstances of barbiturate-related deaths.

Methods: All barbiturate-related deaths identified in the Australian National Coronial Information System were examined. Read More

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http://dx.doi.org/10.1080/15563650.2020.1789653DOI Listing

'Extreme personal stress' and 'a lot of pain': Exploring the physical, mental and social contexts of extramedical pharmaceutical opioid use in Australian paramedic case descriptions.

Drug Alcohol Rev 2020 Jul 7. Epub 2020 Jul 7.

Turning Point, Eastern Health, Melbourne, Australia.

Introduction And Aims: Despite growing concerns over the extramedical use of pharmaceutical opioids, few studies have focused on the contexts that shape this use or how it might lead to harm. There is also limited research examining how contexts might vary across different opioids, such as those with well-established abuse liabilities (e.g. Read More

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http://dx.doi.org/10.1111/dar.13118DOI Listing

Aeromedical retrievals in Queensland: A five-year review.

Emerg Med Australas 2020 Jul 6. Epub 2020 Jul 6.

Discipline of Public Health and Tropical Medicine, College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, Queensland, Australia.

Objective: Aeromedical services are an essential part of the healthcare system. Centralised coordination of aeromedical retrieval tasking offers benefits for safety, timeliness and efficiency in service delivery. The aim of the present study is to review aeromedical retrievals in Queensland exploring patient demographics, temporal patterns and usage characteristics. Read More

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http://dx.doi.org/10.1111/1742-6723.13559DOI Listing

Current outlook and future research needs for harvest weed seed control in North American cropping systems.

Pest Manag Sci 2020 Jul 6. Epub 2020 Jul 6.

Sustainable Agricultural Systems Laboratory, Beltsville Agricultural Research Center, USDA-ARS, Beltsville, MD, USA.

Harvest weed seed control (HWSC) comprises a set of tools and tactics that prevents the addition of weed seed to the soil seed bank, attenuating weed infestations and providing a method to combat the development and spread of herbicide-resistant weed populations. Initial HWSC research efforts in North America are summarized and, combined with the vast area of crops suitable to HWSC, clearly indicate strong potential for this technology. But potential limitations exist that are not present in Australian cropping systems, where HWSC was developed. Read More

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http://dx.doi.org/10.1002/ps.5986DOI Listing

Hyperendemic rheumatic heart disease in a remote Australian town identified by echocardiographic screening.

Med J Aust 2020 Jul 6. Epub 2020 Jul 6.

Royal Darwin Hospital, Darwin, NT.

Objectives: Using echocardiographic screening, to estimate the prevalence of rheumatic heart disease (RHD) in a remote Northern Territory town.

Design: Prospective, cross-sectional echocardiographic screening study; results compared with data from the NT rheumatic heart disease register.

Setting, Participants: People aged 5-20 years living in Maningrida, West Arnhem Land (population, 2610, including 2366 Indigenous Australians), March 2018 and November 2018. Read More

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http://dx.doi.org/10.5694/mja2.50682DOI Listing

Epidemiology of cutaneous sebaceous carcinoma.

Australas J Dermatol 2020 Jul 6. Epub 2020 Jul 6.

South Australian Institute of Ophthalmology, Royal Adelaide Hospital, The University of Adelaide, Adelaide, Australia.

There has been uncertainty about the demographics and anatomical distribution of cutaneous sebaceous carcinoma. This study aims to investigate these uncertainties by analysing data from various countries. Data were obtained from cancer registries of the United States, England, Norway and Taiwan, and incidence rates were calculated with uniform age-adjustment. Read More

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http://dx.doi.org/10.1111/ajd.13387DOI Listing

Functional Outcomes in Patients Admitted to the Intensive Care Unit with Traumatic Brain Injury and Exposed to Hyperoxia: A Retrospective Multicentre Cohort Study.

Neurocrit Care 2020 Jul 6. Epub 2020 Jul 6.

Department of Intensive Care and Hyperbaric Medicine, The Alfred, 55 Commercial Road, Melbourne, VIC, 3004, Australia.

Background: Supplemental oxygen administration to critically ill patients is ubiquitous in the intensive care unit (ICU). Uncertainty persists as to whether hyperoxia is benign in patients with traumatic brain injury (TBI), particularly in regard to their long-term functional neurological outcomes.

Methods: We conducted a retrospective multicenter cohort study of invasively ventilated patients with TBI admitted to the ICU. Read More

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http://dx.doi.org/10.1007/s12028-020-01033-yDOI Listing

Half a century of amyloids: past, present and future.

Chem Soc Rev 2020 Jul 7. Epub 2020 Jul 7.

Department of Health Sciences & Technology, ETH Zurich, Schmelzbergstrasse 9, LFO, E23, 8092 Zurich, Switzerland. and Department of Materials, ETH Zurich, Wolfgang Pauli Strasse 10, 8093 Zurich, Switzerland.

Amyloid diseases are global epidemics with profound health, social and economic implications and yet remain without a cure. This dire situation calls for research into the origin and pathological manifestations of amyloidosis to stimulate continued development of new therapeutics. In basic science and engineering, the cross-β architecture has been a constant thread underlying the structural characteristics of pathological and functional amyloids, and realizing that amyloid structures can be both pathological and functional in nature has fuelled innovations in artificial amyloids, whose use today ranges from water purification to 3D printing. Read More

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http://dx.doi.org/10.1039/c9cs00199aDOI Listing

Genetic reduction of the extracellular matrix protein versican attenuates inflammatory cell infiltration and improves contractile function in dystrophic mdx diaphragm muscles.

Sci Rep 2020 Jul 6;10(1):11080. Epub 2020 Jul 6.

Centre for Molecular and Medical Research, School of Medicine, Deakin University, Waurn Ponds, VIC, 3216, Australia.

There is a persistent, aberrant accumulation of V0/V1 versican in skeletal muscles from patients with Duchenne muscular dystrophy and in diaphragm muscles from mdx mice. Versican is a provisional matrix protein implicated in fibrosis and inflammation in various disease states, yet its role in the pathogenesis of muscular dystrophy is not known. Here, female mdx and male hdf mice (haploinsufficient for the versican allele) were bred. Read More

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http://dx.doi.org/10.1038/s41598-020-67464-xDOI Listing

Body Mass Index From Early to Late Childhood and Cardiometabolic Measurements at 11 to 12 years.

Pediatrics 2020 Jul 6. Epub 2020 Jul 6.

Murdoch Children's Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia.

Objectives: To examine how overweight and obesity at specific ages and overall BMI growth patterns throughout childhood predict cardiometabolic phenotypes at 11 to 12 years.

Methods: In a population-based sample of 5107 infants, BMI was measured every 2 years between ages 2 to 3 and 10 to 11 years. We identified 5 BMI trajectories using growth curve models. Read More

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http://dx.doi.org/10.1542/peds.2019-3666DOI Listing

Nurse-led mind-body relaxation intervention in prison: A multiperspective mixed-method evaluation.

Nurs Outlook 2020 Jul 3. Epub 2020 Jul 3.

Division of Prison Health, Geneva University Hospitals and University of Geneva, Chêne-Bourg, Geneva, Switzerland; Australian Centre for Public and Population Health Research, Faculty of Health, University of Technology, Sydney, NSW, Australia. Electronic address:

Background: Mind-body relaxation techniques are complementary or alternative to medication to manage high stress and anxiety levels in prisons.

Purpose: To assess the motivation to attend and perceived benefits of a nurse-led group relaxation intervention in prison, investigate the experience of participants, prison officers, and health professionals, and identify improvements.

Method: Exploratory study was conducted in a post-trial facility in Switzerland using a multiperspective convergent parallel mixed method drawing from participatory action research principles. Read More

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http://dx.doi.org/10.1016/j.outlook.2020.05.005DOI Listing

Oral medicinal cannabinoids to relieve symptom burden in the palliative care of patients with advanced cancer: a double-blind, placebo-controlled, randomised clinical trial of efficacy and safety of 1:1 delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD).

Trials 2020 Jul 6;21(1):611. Epub 2020 Jul 6.

Mater Health Services, Mater Research Institute-University of Queensland, St Vincent's Private Hospital, Brisbane, Australia.

Background: Despite improvements in medical care, patients with advanced cancer still experience substantial symptom distress. There is increasing interest in the use of medicinal cannabinoids but little high-quality evidence to guide clinicians. This study aims to define the role of a 1:1 delta-9-tetrahydrocannabinol/cannabidiol (THC/CBD) cannabinoid preparation in the management of symptom burden in patients with advanced cancer undergoing standard palliative care. Read More

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http://dx.doi.org/10.1186/s13063-020-04541-6DOI Listing

Effects of a novel nutraceutical combination (BruMeChol™) in subjects with mild hypercholesterolemia: study protocol of a randomized, double-blind, controlled trial.

Trials 2020 Jul 6;21(1):616. Epub 2020 Jul 6.

Cardiology Unit, IRCCS INRCA, Via della Montagnola 81, 60131, Ancona, Italy.

Background: Elevated cholesterol levels and systemic inflammation are considered relevant risk factors for cardiovascular disease (CVD) development and progression. Increasing evidence suggests that cholesterol-lowering and inflammation-lowering nutraceuticals are useful in the management of moderate hypercholesterolemia. Here, we describe the study protocol of a clinical trial aimed to evaluate the cholesterol and inflammatory lowering effect of an innovative dietary supplement (BruMeChol™, Mivell S. Read More

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http://dx.doi.org/10.1186/s13063-020-04551-4DOI Listing

Recruiting a representative sample of urban South Australian Aboriginal adults for a survey on alcohol consumption.

BMC Med Res Methodol 2020 Jul 6;20(1):183. Epub 2020 Jul 6.

Faculty of Medicine and Health, Discipline of Addiction Medicine, NHMRC Centre of Research Excellence in Indigenous Health and Alcohol, The University of Sydney, King George V Building, 83-117 Missenden Road, Camperdown, NSW, 2050, Australia.

Background: Population estimates of alcohol consumption vary widely among samples of Aboriginal and Torres Strait Islander (Indigenous) Australians. Some of this difference may relate to non-representative sampling. In some communities, household surveys are not appropriate and phone surveys not feasible. Read More

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http://dx.doi.org/10.1186/s12874-020-01067-yDOI Listing

What methods are used to promote patient and family involvement in healthcare regulation? A multiple case study across four countries.

BMC Health Serv Res 2020 Jul 6;20(1):616. Epub 2020 Jul 6.

Erasmus School of Health Policy and Management, Erasmus University, Rotterdam, the Netherlands.

Background: In the regulation of healthcare, the subject of patient and family involvement figures increasingly prominently on the agenda. However, the literature on involving patients and families in regulation is still in its infancy. A systematic analysis of how patient and family involvement in regulation is accomplished across different health systems is lacking. Read More

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http://dx.doi.org/10.1186/s12913-020-05471-4DOI Listing

Sarcoma epidemiology and cancer-related hospitalisation in Western Australia from 1982 to 2016: a descriptive study using linked administrative data.

BMC Cancer 2020 Jul 6;20(1):625. Epub 2020 Jul 6.

Health Economics and Data Analytics, School of Public Health, Faculty of Health Sciences, Curtin University, GPO Box U1987, Perth, Western Australia, 6845, Australia.

Background: Sarcomas are a heterogeneous group of malignancies arising from mesenchymal cells. Epidemiological studies on sarcoma from Australia are lacking, as previous studies have focused on a sarcoma type (e.g. Read More

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http://dx.doi.org/10.1186/s12885-020-07103-wDOI Listing

Weight management barriers and facilitators after breast cancer in Australian women: a national survey.

BMC Womens Health 2020 Jul 6;20(1):140. Epub 2020 Jul 6.

ICON Cancer Centre, Sydney Adventist Hospital, Wahroonga, NSW, 2076, Australia.

Background: Breast cancer is the most common cancer in women worldwide. Weight gain after breast cancer is associated with poorer health outcomes. The aim of this study was to describe how Australian breast cancer survivors are currently managing their weight. Read More

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http://dx.doi.org/10.1186/s12905-020-01002-9DOI Listing

Understanding the Biology of Human Interstitial Cells of Cajal in Gastrointestinal Motility.

Int J Mol Sci 2020 Jun 25;21(12). Epub 2020 Jun 25.

School of Medicine, Western Sydney University, Campbelltown, NSW 2560, Australia.

Millions of patients worldwide suffer from gastrointestinal (GI) motility disorders such as gastroparesis. These disorders typically include debilitating symptoms, such as chronic nausea and vomiting. As no cures are currently available, clinical care is limited to symptom management, while the underlying causes of impaired GI motility remain unaddressed. Read More

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http://dx.doi.org/10.3390/ijms21124540DOI Listing

Thermal Requirements Underpinning Germination Allude to Risk of Species Decline from Climate Warming.

Plants (Basel) 2020 Jun 25;9(6). Epub 2020 Jun 25.

Department of Biodiversity, Conservation and Attractions, Locked Bag 104, Bentley Delivery Centre, Western Australia 6983, Australia.

The storage of seeds is a commonly used means of preserving plant genetic diversity in the face of rising threats such as climate change. Here, the findings of research from the past decade into thermal requirements for germination are synthesised for more than 100 plant species from southern Western Australia. This global biodiversity hotspot is predicted to suffer major plant collapse under forecast climate change. Read More

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http://dx.doi.org/10.3390/plants9060796DOI Listing

Cross-Species BAC Mapping Highlights Conservation of Chromosome Synteny across Dragon Lizards (Squamata: Agamidae).

Genes (Basel) 2020 Jun 25;11(6). Epub 2020 Jun 25.

Institute for Applied Ecology, University of Canberra, Bruce, ACT 2617, Australia.

Dragon lizards (Squamata: Agamidae) comprise about 520 species in six subfamilies distributed across Asia, Australasia and Africa. Only five species are known to have sex chromosomes. All of them possess ZZ/ZW sex chromosomes, which are microchromosomes in four species from the subfamily Amphibolurinae, but much larger in from the subfamily Agaminae. Read More

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http://dx.doi.org/10.3390/genes11060698DOI Listing

Leachate Analysis of Heavy Metals in Cigarette Butts and Bricks Incorporated with Cigarette Butts.

Materials (Basel) 2020 Jun 25;13(12). Epub 2020 Jun 25.

School of Engineering, RMIT University, Melbourne 3000, Australia.

Billions of cigarette butts (CBs) are discarded as litter in the environment every year worldwide. As CBs have poor biodegradability, it can take several years for them to break down while leaching toxic chemicals and heavy metals. Mohajerani et al. Read More

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http://dx.doi.org/10.3390/ma13122843DOI Listing

Exploring Therapeutic Targets to Reverse or Prevent the Transition from Metabolically Healthy to Unhealthy Obesity.

Cells 2020 Jul 1;9(7). Epub 2020 Jul 1.

Medical School, Australian National University, Canberra, ACT 2601, Australia.

The prevalence of obesity and obesity-related metabolic comorbidities are rapidly increasing worldwide, placing a huge economic burden on health systems. Excessive nutrient supply combined with reduced physical exercise results in positive energy balance that promotes adipose tissue expansion. However, the metabolic response and pattern of fat accumulation is variable, depending on the individual's genetic and acquired susceptibility factors. Read More

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http://dx.doi.org/10.3390/cells9071596DOI Listing

Ultra-Processed Foods and Health Outcomes: A Narrative Review.

Nutrients 2020 Jun 30;12(7). Epub 2020 Jun 30.

School of Exercise and Nutrition Science, Deakin University, Geelong 3217, Australia.

The nutrition literature and authoritative reports increasingly recognise the concept of ultra-processed foods (UPF), as a descriptor of unhealthy diets. UPFs are now prevalent in diets worldwide. This review aims to identify and appraise the studies on healthy participants that investigated associations between levels of UPF consumption and health outcomes. Read More

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http://dx.doi.org/10.3390/nu12071955DOI Listing

Wheat Sensitivity and Functional Dyspepsia: A Pilot, Double-Blind, Randomized, Placebo-Controlled Dietary Crossover Trial with Novel Challenge Protocol.

Nutrients 2020 Jun 30;12(7). Epub 2020 Jun 30.

Faculty of Health and Medicine, University of Newcastle, Callaghan, NSW 2308, Australia.

Functional dyspepsia (FD), characterised by symptoms of epigastric pain or early satiety and post prandial distress, has been associated with duodenal eosinophilia, raising the possibility that it is driven by an environmental allergen. Non-coeliac gluten or wheat sensitivity (NCG/WS) has also been associated with both dyspeptic symptoms and duodenal eosinophilia, suggesting an overlap between these two conditions. The aim of this study was to evaluate the role of wheat (specifically gluten and fructans) in symptom reduction in participants with FD in a pilot randomized double-blind, placebo controlled, dietary crossover trial. Read More

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http://dx.doi.org/10.3390/nu12071947DOI Listing

It Takes Two: Dimerization Is Essential for the Broad-Spectrum Predatory and Defensive Activities of the Venom Peptide Mp1a from the Jack Jumper Ant .

Biomedicines 2020 Jun 30;8(7). Epub 2020 Jun 30.

Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD 4072, Australia.

Ant venoms have recently attracted increased attention due to their chemical complexity, novel molecular frameworks, and diverse biological activities. The heterodimeric peptide ∆-myrtoxin-Mp1a (Mp1a) from the venom of the Australian jack jumper ant, , exhibits antimicrobial, membrane-disrupting, and pain-inducing activities. In the present study, we examined the activity of Mp1a and a panel of synthetic analogues against the gastrointestinal parasitic nematode , the fruit fly , and for their ability to stimulate pain-sensing neurons. Read More

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http://dx.doi.org/10.3390/biomedicines8070185DOI Listing

Peptide-Mediated Liposome Fusion as a Tool for the Detection of Matrix Metalloproteinases.

Adv Biosyst 2019 May 12;3(5):e1800330. Epub 2019 Mar 12.

School of Chemical Engineering and Australian Centre for Nanomedicine (ACN), The University of New South Wales (UNSW Sydney), Sydney, NSW, 2052, Australia.

Biological cells continue to inspire the development of technologies toward rapid, sensitive, and selective detection of analytes. Membrane fusion is a key biological event in living cells that involves a highly selective recognition mechanism controlled by different functional proteins. Herein, liposome-liposome fusion mediated by coiled-coil forming peptides JR2EC and JR2KC to mimic biological membrane fusion is reported. Read More

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http://dx.doi.org/10.1002/adbi.201800330DOI Listing

Carbon Nanotubes and Graphene as Nanoreinforcements in Metallic Biomaterials: a Review.

Adv Biosyst 2019 Mar 13;3(3):e1800212. Epub 2019 Feb 13.

School of Engineering, RMIT University, Bundoora, Victoria, 3083, Australia.

Current challenges in existing metallic biomaterials encourage undertaking research in the development of novel materials for biomedical applications. This paper critically reviews the potential of carbon nanotubes (CNT) and graphene as nanoreinforcements in metallic biomaterials for bone tissue engineering. Unique and remarkable mechanical, electrical, and biological properties of these carbon nanomaterials allow their use as secondary-phase reinforcements in monolithic biomaterials. Read More

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http://dx.doi.org/10.1002/adbi.201800212DOI Listing

Setting of import tolerances for haloxyfop-P in linseed and rapeseed.

EFSA J 2018 Nov 2;16(11):e05470. Epub 2018 Nov 2.

In accordance with Article 6 of Regulation (EC) No 396/2005, the Australian Government Department of Agriculture and Water Resources submitted two requests to the competent national authority in Denmark to set import tolerances for the active substance haloxyfop-P in linseed and rapeseed. The data submitted in support of the request were found to be sufficient to derive maximum residue level (MRL) proposals for linseed and rapeseed. Adequate analytical methods for enforcement are available to control the residues of haloxyfop-P in plant matrices under consideration at the validated limit of quantification (LOQ) of 0. Read More

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http://dx.doi.org/10.2903/j.efsa.2018.5470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009466PMC
November 2018

Pest categorisation of the species complex.

EFSA J 2018 Jan 22;16(1):e05107. Epub 2018 Jan 22.

The Panel on Plant health performed a pest categorisation of the Australian Eucalyptus snout-beetle (Coleoptera: Curculionidae), for the EU. should be referred as the species complex because it includes several cryptic species. A complete nomenclature of the species present in the EU is still pending. Read More

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http://dx.doi.org/10.2903/j.efsa.2018.5107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009585PMC
January 2018

Picolinic acid, a catabolite of tryptophan, has an anabolic effect on bone in vivo.

J Bone Miner Res 2020 Jul 6. Epub 2020 Jul 6.

Neuroinflammation Group, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, New South Wales, Australia.

Fractures due to osteoporosis have a severe impact on our older population. Reports of side effects with commonly prescribed osteoporosis drugs have led to the investigation of new and safer treatments with novel mechanisms of action. Picolinic acid (PIC), a catabolite of tryptophan, induces in vitro osteogenic differentiation of mesenchymal stem cells. Read More

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http://dx.doi.org/10.1002/jbmr.4125DOI Listing

A citizen-science approach reveals long-term social network structure in an urban parrot, Cacatua galerita.

J Anim Ecol 2020 Jul 6. Epub 2020 Jul 6.

Centre for Ecosystem Science, School of Biological, Earth and Environmental Sciences, UNSW, Sydney, NSW, 2052, Australia.

Parrots are often referenced in discussions of social and cognitive complexity, yet relatively little is known of their social organisation in the wild. In particular, the presence of long-lasting social ties has been highlighted as a hallmark of social complexity, however the presence of such ties can be masked in fission-fusion systems like that exhibited by most parrot species. Social network analysis has the potential to elucidate such multi-level dynamics. Read More

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http://dx.doi.org/10.1111/1365-2656.13295DOI Listing

Tandem detection of organic and inorganic gunshot residues using LC-MS and SEM-EDS.

Forensic Sci Int 2020 Jun 24;314:110389. Epub 2020 Jun 24.

College of Science and Engineering, Flinders University, Bedford Park, South Australia, Australia. Electronic address:

Gunshot residue (GSR) is a valuable form of forensic trace evidence in the investigation of firearms crime. The current gold-standard approach does not include the analysis of organic components of the residues, which may be a deficiency, particularly in cases where there is little to no inorganic gunshot residue (IGSR) present or its attribution to a firearm source is ambiguous. A solvent extraction method was used for the extraction of organic GSR (OGSR) from the most common sampling device used to collect IGSR (i. Read More

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http://dx.doi.org/10.1016/j.forsciint.2020.110389DOI Listing

Current trauma care system in Saudi Arabia: A scoping literature review.

Accid Anal Prev 2020 Jul 3;144:105653. Epub 2020 Jul 3.

Alfred Health Clinical School, La Trobe University, Prahran, Victoria, Australia.

Background: Trauma is one of the leading causes of death worldwide with millions of people dying each year, particularly in low or middle-income countries. This paper describes and evaluates the current trauma system (TS) in Saudi Arabia (SA).

Methods: A scoping literature review was performed, incorporating an extensive search of Medline and Embase databases for refereed literature, as well as a search of grey literature to locate unpublished articles or reports in English or Arabic. Read More

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http://dx.doi.org/10.1016/j.aap.2020.105653DOI Listing

Comparative transcriptome analysis of pilchard orthomyxovirus (POMV) and infectious salmon anaemia virus (ISAV).

Fish Shellfish Immunol 2020 Jul 3. Epub 2020 Jul 3.

CSIRO Agriculture and Food, Aquaculture Program, Hobart, Tasmania, Australia.

The Tasmanian Atlantic salmon (Salmo salar) aquaculture industry had remained relatively free of major viral diseases until the recent emergence of pilchard orthomyxovirus (POMV). The virus originally isolated from wild pilchards in Southern Australia is of great concern to the industry as it can cause high mortality. Despite its classification in the Orthomyxoviridae family, POMV is genetically divergent from infectious salmon anaemia virus (ISAV) and potentially represents a new genus within the family. Read More

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http://dx.doi.org/10.1016/j.fsi.2020.06.050DOI Listing

Comparison of an early warning score to single-triggering warning system for inpatient deterioration: An audit of 4089 medical emergency calls.

Resuscitation 2020 Jul 3. Epub 2020 Jul 3.

Medical School, Australian National University, Florey Building 54 Mills Road, Acton, ACT 2601 Australia; Intensive Care Unit, Canberra Hospital, Yamba Dr, Garran, ACT 2605, Australia; Centre for Advances in Epidemiology & IT, Canberra Hospital, Yamba Dr, Garran, ACT 2605, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.resuscitation.2020.06.026DOI Listing

Impact of low-level viraemia on virological failure among Asian children with perinatally acquired HIV on first-line combination antiretroviral treatment: a multicentre, retrospective cohort study.

J Int AIDS Soc 2020 Jul;23(7):e25550

Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand.

Introduction: The clinical relevance of low-level viraemia (LLV) and virological outcomes among children living with HIV (CLHIV) remains controversial. This study aimed to determine the impact of LLV on virological failure (VF) among Asian CLHIV on first-line combination antiretroviral therapy (cART).

Methods: CLHIV aged <18 years, who were on first-line cART for ≥12 months, and had virological suppression (two consecutive plasma viral load [pVL] <50 copies/mL) were included. Read More

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http://dx.doi.org/10.1002/jia2.25550DOI Listing

A Geometric Clustering Tool (AGCT) to robustly unravel the inner cluster structures of time-series gene expressions.

PLoS One 2020 6;15(7):e0233755. Epub 2020 Jul 6.

Sony Computer Science Laboratories Inc., Tokyo, Japan.

Systems biology aims at holistically understanding the complexity of biological systems. In particular, nowadays with the broad availability of gene expression measurements, systems biology challenges the deciphering of the genetic cell machinery from them. In order to help researchers, reverse engineer the genetic cell machinery from these noisy datasets, interactive exploratory clustering methods, pipelines and gene clustering tools have to be specifically developed. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0233755PLOS

A reduction in reported alcohol use in pregnancy in Australian Aboriginal communities: a prevention campaign showing promise.

Aust N Z J Public Health 2020 Jul 6. Epub 2020 Jul 6.

Telethon Kids Institute, The University of Western Australia, Perth, Western Australia.

Objective: Aboriginal leaders in remote Western Australian communities with high rates of prenatal alcohol exposure invited researchers to evaluate the community-led Marulu foetal alcohol spectrum disorder (FASD) Prevention Strategy initiated in 2010.

Methods: The proportion of women reporting alcohol use during pregnancy to midwives was compared between 2008, 2010 and 2015. Initial midwife appointments were calculated by weeks of gestation. Read More

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http://dx.doi.org/10.1111/1753-6405.13012DOI Listing

Australian first in Aboriginal and Torres Strait Islander prisoner health care in the Australian Capital Territory.

Aust N Z J Public Health 2020 Jul 6. Epub 2020 Jul 6.

Winnunga Nimmityjah Aboriginal Health and Community Services, Australian Capital Territory.

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http://dx.doi.org/10.1111/1753-6405.13007DOI Listing

sp. nov., a plant-pathogenic bacterium isolated from sugar cane ().

Int J Syst Evol Microbiol 2020 Jul 6. Epub 2020 Jul 6.

Université de Lyon, CNRS UMR 5240, INSA de Lyon, Université Claude Bernard Lyon 1, Microbiologie Adaptation et Pathogénie, F-69621 Villeurbanne, France.

The genus is an important group of plant pathogens that currently comprises 10 recognized species. Although most isolates originated from infected cultivated plants, they are also isolated from water. The genomic sequence of the Australian strain NCPPB 569 clearly established its separation from the previously characterized species. Read More

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http://dx.doi.org/10.1099/ijsem.0.004306DOI Listing

Phenotype-genotype correlations in a pseudodominant Stargardt disease pedigree due to a novel ABCA4 deletion-insertion variant causing a splicing defect.

Mol Genet Genomic Med 2020 Jul 23;8(7):e1259. Epub 2020 Apr 23.

Centre for Ophthalmology and Visual Science (Incorporating Lions Eye Institute), The University of Western Australia, Nedlands, Western Australia, Australia.

Background: Deletion-insertion (delins) variants in the retina-specific ATP-binding cassette transporter gene, subfamily A, member 4 (ABCA4) accounts for <1% in Stargardt disease. The consequences of these delins variants on splicing cannot be predicted with certainty without supporting in vitro data.

Methods: Candidate ABCA4 variants were revealed by genetic and segregation analysis of a family with pseudodominant Stargardt disease using a commercial panel and Sanger sequencing. Read More

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http://dx.doi.org/10.1002/mgg3.1259DOI Listing