137,098 results match your criteria Australian Forestry[Journal]

Preliminary psychometric evaluation of the patient reported experience measure for addiction treatment (PREMAT).

Addict Behav 2021 Jul 12;123:107048. Epub 2021 Jul 12.

School of Psychology, University of Wollongong, Australia; Illawarra Health and Medical Research Institute, University of Wollongong, Australia.

Introduction: Patient-reported experience measures (PREMs) are recommended for use in evaluating person-centred care. To date, a PREM has not been validated for residential alcohol and other drug (AOD) treatment. Utilising items developed through a previously published qualitative study informing the development of the PREM for Addiction Treatment (PREMAT), the current study conducted a psychometric evaluation and validation of the PREMAT. Read More

View Article and Full-Text PDF

Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention.

Cell Chem Biol 2021 Jul 28. Epub 2021 Jul 28.

Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee DD1 5EH, UK.

We identify the Plasmodium falciparum acetyl-coenzyme A synthetase (PfAcAS) as a druggable target, using genetic and chemical validation. In vitro evolution of resistance with two antiplasmodial drug-like compounds (MMV019721 and MMV084978) selects for mutations in PfAcAS. Metabolic profiling of compound-treated parasites reveals changes in acetyl-CoA levels for both compounds. Read More

View Article and Full-Text PDF

The Modernization of Radiation Therapy Services in Cambodia: A Model of International Collaboration.

Int J Radiat Oncol Biol Phys 2021 Sep;111(1):14-22

Collaboration for Cancer Outcomes, Research and Evaluation (CCORE), Ingham Institute for Applied Medical Research, UNSW Sydney, Liverpool, Australia; Liverpool and Macarthur Cancer Therapy Centres, Western Sydney University, Campbelltown, Australia; School of Public Health, Faculty of Medicine and Health, University of Sydney, Camperdown, Australia. Electronic address:

Purpose: Cambodia is a Southeast Asian low-middle-income country with a population of >15 million. In 2020, Cambodia was estimated to have 18,375 new diagnoses of cancer and 12,638 deaths attributable to cancer. Cambodia was estimated to have a deficit of 16 megavoltage machines in 2012. Read More

View Article and Full-Text PDF
September 2021

Post-transplant maintenance therapy for MDS and AML: a bridge too far or the beginning of a new era?

Leuk Lymphoma 2021 Aug 4:1-5. Epub 2021 Aug 4.

Australian Centre for Blood Diseases, Monash University, Melbourne, VIC, Australia.

View Article and Full-Text PDF

Increasing Antibiotic Susceptibility: The Use of Cationic Gold Nanoparticles in Gram-Negative Bacterial Membrane Models.

Langmuir 2021 Aug 4. Epub 2021 Aug 4.

Flinders Institute for Nanoscale Science and Technology, Flinders University, Bedford Park 5042, South Australia.

Antibiotic resistance will be one of the most prominent challenges to health-care systems in the coming decades, with the OECD predicting that up to 2.4 million deaths will be caused between 2015 and 2050 by drug-resistant bacterial infections in first-world countries alone, with infections costing health-care systems billions of dollars each year. Developing new methods to increase bacterial susceptibility toward drugs is an important step in treating resistant infections. Read More

View Article and Full-Text PDF

Comparing the first-attempt tracheal intubation success of the hyperangulated McGrath® X-blade vs the Macintosh-type CMAC videolaryngoscope in patients with cervical immobilization: a two-centre randomized controlled trial.

J Clin Monit Comput 2021 Aug 4. Epub 2021 Aug 4.

Khoo Teck Puat Hospital, 90 Yishun Central, Singapore, 768828, Singapore.

We compared the hyperangulated McGrath X-blade with the Macintosh-type CMAC videolaryngoscope through the use of manual in-line stabilization on patients. The primary hypothesis was that the McGrath X-blade has a similar first-attempt success rate as the CMAC videolaryngoscope. 210 patients of ASA physical status I to III, aged 21 to 80 years old, undergoing general anesthesia requiring tracheal intubation were prospectively recruited into this two-centre randomized controlled trial, from June 2016 to April 2019. Read More

View Article and Full-Text PDF

Characterization of Skeletal Phenotype and Associated Mechanisms With Chronic Intestinal Inflammation in the Winnie Mouse Model of Spontaneous Chronic Colitis.

Inflamm Bowel Dis 2021 Aug 4. Epub 2021 Aug 4.

Department of Medicine-Western Health, The University of Melbourne, Melbourne, VIC, Australia.

Background: Osteoporosis is a common extraintestinal manifestation of inflammatory bowel disease (IBD). However, studies have been scarce, mainly because of the lack of an appropriate animal model of colitis-associated bone loss. In this study, we aimed to decipher skeletal manifestations in the Winnie mouse model of spontaneous chronic colitis, which carries a MUC2 gene mutation and closely replicates ulcerative colitis. Read More

View Article and Full-Text PDF

The evolution of comparative phylogeography: putting the geography (and more) into comparative population genomics.

Genome Biol Evol 2021 Aug 4. Epub 2021 Aug 4.

Research School of Biology, The Australian National University, Canberra, ACT, 0200, Australia.

Comparative population genomics is an ascendant field using genomic comparisons between species to draw inferences about forces regulating genetic variation. Comparative phylogeography, by contrast, focuses on the shared lineage histories of species co-distributed geographically and is decidedly organismal in perspective. Comparative phylogeography is approximately 35 years old, and, by some metrics, is showing signs of reduced growth. Read More

View Article and Full-Text PDF

Effect of Graphic Warning Labels on Cigarette Packs on US Smokers' Cognitions and Smoking Behavior After 3 Months: A Randomized Clinical Trial.

JAMA Netw Open 2021 Aug 2;4(8):e2121387. Epub 2021 Aug 2.

Cancer Control Program, Moores Cancer Center, University of California, San Diego, La Jolla.

Importance: The US Food and Drug Administration's implementation of graphic warning labels (GWLs) on cigarette packs is under challenge in US courts.

Objective: To determine whether GWLs can affect US smokers' perceptions about their cigarettes or health consequences and changes in smoking behavior.

Design, Setting, And Participants: This study was a randomized clinical trial of the effect of a 3-month, real-world experience of cigarettes with GWL packaging. Read More

View Article and Full-Text PDF

Posture and Muscle Activity during Waste Collection Work.

Ann Work Expo Health 2021 Aug 4. Epub 2021 Aug 4.

Banyule City Council, 1 Flintoff St, Greensborough, Victoria, Australia.

The musculoskeletal load in waste collection has been examined through simulated assessment of pulling and pushing bins as well as lifting and throwing rubbish bags. With the onset of mechanization, many of these tasks do not exist and workers are faced with other loads not previously assessed. The purpose of this study was to quantify the postures and muscle activity during mechanized waste collection work. Read More

View Article and Full-Text PDF

Metabolic rates of aggressive and submissive phenotypes are colour blind in the polymorphic Gouldian finch.

J Exp Biol 2021 Aug 4;224(15). Epub 2021 Aug 4.

Department of Biological Sciences, Macquarie University, Sydney, NSW 2109, Australia.

Evidence from a number of species suggests that behaviours associated with social rank are positively correlated with metabolic rate. These studies, however, are based on metabolic measurements of isolated individuals, thereby ignoring potential effects of social interactions on metabolic rates. Here, we characterised three pertinent metabolic indices in the two predominant genetic colour morphs of the Gouldian finch (Erythrura gouldiae): diurnal resting metabolic rate (RMR), nocturnal basal metabolic rate (BMR) and exercise-induced maximal metabolic rate (MMR). Read More

View Article and Full-Text PDF

Neutron diffraction study of the monoclinic - tetragonal phase transition in NdNbO and NdTaO.

Dalton Trans 2021 Aug 4. Epub 2021 Aug 4.

School of Chemistry, The University of Sydney, Sydney, New South Wales 2006, Australia.

Phase transition and high-temperature properties of NdNbO4 and NdTaO4 were studied in situ using powder neutron diffraction methods. Both oxides undergo a reversible phase transition from a monoclinic I2/a phase at low temperatures to a tetragonal I41/a phase at high temperatures. The phase transition has been investigated through analysis of the spontaneous strains and symmetry distortion modes. Read More

View Article and Full-Text PDF

Construction of an iminoketenylidene.

Chem Commun (Camb) 2021 Aug 4. Epub 2021 Aug 4.

Research School of Chemistry, Australian National University, Canberra, Australian Capital Territory, ACT 2601, Australia.

The new isonitrile-μ-carbido complexes [WPt(μ-C)Br(CNR)(PPh3)(CO)2(Tp*)] (R = C6H2Me3-2,4,6, C6H3Me2-2,6; Tp* = hydrotris(dimethylpyrazolyl)borate) rearrange irreversibly in polar solvents to provide the first examples of iminoketenylidene (CCNR) complexes. Read More

View Article and Full-Text PDF

Vitamin E-facilitated carbon monoxide pro-drug nanomedicine for efficient light-responsive combination cancer therapy.

Biomater Sci 2021 Aug 4. Epub 2021 Aug 4.

Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD 4072, Australia.

The quest to maximize therapeutic efficiency in cancer treatment requires innovative delivery nanoplatforms capable of employing different modules simultaneously. Combination therapy has proven to be one of the best anticancer strategies so far. Herein, we have developed a lipid-encapsulated nanoplatform that combines chemotherapy with photoresponsive gas therapy for colon cancer treatment. Read More

View Article and Full-Text PDF

Optimizing coral reef recovery with context-specific management actions at prioritized reefs.

J Environ Manage 2021 Jul 15;295:113209. Epub 2021 Jul 15.

CSIRO Oceans and Atmosphere, St Lucia, QLD 4067, Australia. Electronic address:

Assisting the natural recovery of coral reefs through local management actions is needed in response to increasing ecosystem disturbances in the Anthropocene. There is growing evidence that commonly used resilience-based passive management approaches may not be sufficient to maintain coral reef key functions. We synthesize and discuss advances in coral reef recovery research, and its application to coral reef conservation and restoration practices. Read More

View Article and Full-Text PDF

Differential tolerance of species alters the seasonal response of marine epifauna to extreme warming.

Sci Total Environ 2021 Jul 22;797:149215. Epub 2021 Jul 22.

Evolution and Ecology Research Centre, School of Biological, Earth and Environmental Sciences, University of New South Wales, Sydney, NSW 2052, Australia.

Marine heatwaves are occurring with greater frequency and magnitude worldwide and can significantly alter community structure and ecosystem function. Predicting changes in community structure in extreme temperatures requires an understanding of variation among species in their thermal tolerance, and how potential acclimatization to recent temperatures influences survival. To address this, we determined the tolerance to extreme temperatures in a crustacean epifaunal assemblage that inhabits macroalgae in the southeast Australian ocean warming hotspot. Read More

View Article and Full-Text PDF

Are we overlooking the rural patient journey when it comes to sepsis diagnosis and management?

Jordan Kirby

Emerg Med Australas 2021 Aug 3. Epub 2021 Aug 3.

Warrnambool Clinical School, School of Medicine, Deakin University, Geelong, Victoria, Australia.

Surviving Sepsis Campaign guidelines have progressively moved towards faster time-based treatment targets over recent years despite international data consistently showing low protocol adherence. A key stakeholder in Australian healthcare remains overlooked in sepsis research: the under-resourced rural ED. The journey of the rural patient markedly differs to that of the metropolitan patient, involving greater reliance upon patient transfers, reduced staffing and resource inaccessibility, directly impacting on sepsis protocol adherence and patient outcomes. Read More

View Article and Full-Text PDF

Variation in inpatient allied health service provision in Australian and New Zealand hospitals.

Australas J Ageing 2021 Aug 3. Epub 2021 Aug 3.

School of Primary and Allied Health Care, Monash University Peninsula Campus, Melbourne, Vic., Australia.

Objective: To describe the variability of allied health services on weekends, relative to weekdays, throughout Australian and New Zealand hospitals.

Methods: A prospective, cross-sectional observational study embedded within a cluster randomised control trial. Allied health managers provided administrative data relating to allied health service events. Read More

View Article and Full-Text PDF

E-Health and remote management of patients with inflammatory bowel disease: lessons from Denmark in a time of need.

Intern Med J 2021 Aug 3. Epub 2021 Aug 3.

Department of Gastroenterology, Alfred Health and Monash University, Melbourne, Victoria, Australia.

In Denmark, remote monitoring and management of inflammatory bowel disease (IBD) started two decades ago with the web application Constant Care. The disease monitoring in Constant Care consists of simple disease activity questionnaires and home measurement of faecal calprotectin, a stool biomarker for inflammation. It has now been implemented in clinical practice at North Zealand University Hospital in Denmark. Read More

View Article and Full-Text PDF

A Congruent-Melting Mid-Infrared Nonlinear Optical Vanadate Exhibiting Strong Second-Harmonic Generation.

Angew Chem Int Ed Engl 2021 Aug 4. Epub 2021 Aug 4.

Tongji University, China-Australia Joint Research Centre for Functional Molecular Materials, School of Chemical Science and Engineering, 1239 Siping Road, 200092, Shanghai, CHINA.

Mid-infrared (mid-IR) nonlinear optical (NLO) materials are vital for the development of photonics research and state-of-the-art laser technology, but the study of these important optoelectronic materials is hindered by the competing requirements of optimized second-harmonic generation (SHG) coefficient dij and laser-induced damage threshold (LIDT), as well as the harsh synthetic conditions that are usually needed. Herein, we report the facile hydrothermal synthesis of a polar NLO vanadate Cs4V8O22 (CVO) featuring a quasi-rigid honeycomb-layered structure with [VO4] and [VO5] polyhedra aligned parallel. CVO possesses a wide IR-transparent window, high LIDT, and congruent-melting behavior. Read More

View Article and Full-Text PDF

Sharp and fully loaded: 3D tissue reconstruction reveals how snake fangs stay deadly during fang replacement.

J Anat 2021 Aug 3. Epub 2021 Aug 3.

School of Biological Sciences, Monash University, VIC, Australia.

Snake venom is produced, transported and delivered by the sophisticated venom delivery system (VDS). When snakes bite, the venom travels from the venom gland through the venom duct into needle-like fangs that inject it into their prey. To counteract breakages, fangs are continuously replaced throughout life. Read More

View Article and Full-Text PDF

Testing for Prohibited Substances in Rural Agricultural Show Exhibits: A Twenty-three Year Experience.

J Anal Toxicol 2021 Aug 4. Epub 2021 Aug 4.

Notre Dame Clinical School, Wagga Wagga, NSW 2650, Australia.

The administration of prohibited substances has been used in agricultural show competitions and animal racing industries to gain unfair competitive advantages. We report the first large prospectively designed descriptive study of drug testing in four species (n=1598) over a twenty three year period. RESULTS: 4. Read More

View Article and Full-Text PDF

How will mass-vaccination change COVID-19 lockdown requirements in Australia?

Lancet Reg Health West Pac 2021 Sep 30;14:100224. Epub 2021 Jul 30.

Centre for Complex Systems, Faculty of Engineering, University of Sydney, Sydney, NSW 2006, Australia.

To prevent future outbreaks of COVID-19, Australia is pursuing a mass-vaccination approach in which a targeted group of the population comprising healthcare workers, aged-care residents and other individuals at increased risk of exposure will receive a highly effective priority vaccine. The rest of the population will instead have access to a less effective vaccine. We apply a large-scale agent-based model of COVID-19 in Australia to investigate the possible implications of this hybrid approach to mass-vaccination. Read More

View Article and Full-Text PDF
September 2021

Carcinogenicity of fibrous glaucophane: How should we fill the data gaps?

Curr Res Toxicol 2021 18;2:202-203. Epub 2021 May 18.

Chemistry & Industrial Hygiene, Inc., 10201 W. 43rd Avenue, Suite 201, Wheat Ridge, CO 80033, USA.

•The modeled glaucophane mesothelioma potency is 0.0085 % vs. 0. Read More

View Article and Full-Text PDF

Models of care for osteoporosis: A systematic scoping review of efficacy and implementation characteristics.

EClinicalMedicine 2021 Aug 14;38:101022. Epub 2021 Jul 14.

Monash Centre for Health Research and Implementation, Monash University, Locked Bag 29, Clayton, Vic 3168, Australia.

Background: Osteoporosis affects over half of adults over 50 years worldwide. With an ageing population, osteoporosis, fractures and their associated costs are increasing. Unfortunately, despite effective therapies, many with osteoporosis remain undiagnosed and untreated. Read More

View Article and Full-Text PDF

Nurses as Stakeholders in the Adoption of Mobile Technology in Australian Health Care Environments: Interview Study.

JMIR Nurs 2019 Jan-Dec;2(1):e14279. Epub 2019 Aug 9.

College of Arts, Law and Education School of Social Sciences University of Tasmania Launceston Australia.

Background: The 2017 Australian Digital Health Agency (ADHA) Strategy is based on the underlying assumption that digital technology in health care environments is ubiquitous. The ADHA Strategy views health professionals, especially nurses, as grappling with the complexity of installing and using digital technologies to facilitate personalized and sustainable person-centered care. Yet, ironically, the 2018 debate over how to enroll Australians into the national electronic health record system and its alteration from an opt-in to an opt-out model heightened public and professional concern over what constituted a "safe, seamless and secure" health information system. Read More

View Article and Full-Text PDF

Mechanistic Insights on How to Avoid and Harness Cyanine Photoconversion.

ACS Cent Sci 2021 Jul 18;7(7):1095-1098. Epub 2021 Jun 18.

School of Chemistry, Faculty of Science, The University of Sydney Nano Institute (Sydney Nano) and Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Sydney, Sydney, NSW 2006, Australia.

View Article and Full-Text PDF

Evaluation of a novel, multi-functional inhibitor compound for prevention of biofilm formation on carbon steel in marine environments.

Sci Rep 2021 Aug 3;11(1):15697. Epub 2021 Aug 3.

Curtin Corrosion Centre, WA School of Mines: Minerals, Energy and Chemical Engineering, Curtin University, Kent Street, Bentley, WA, 6102, Australia.

Chemical biocides remain the most effective mitigation strategy against microbiologically influenced corrosion (MIC), one of the costliest and most pervasive forms of corrosion in industry. However, toxicity and environmental concerns associated with these compounds are encouraging the development of more environmentally friendly MIC inhibitors. In this study, we evaluated the antimicrobial effect of a novel, multi-functional organic corrosion inhibitor (OCI) compound, cetrimonium trans-4-hydroxy-cinnamate (CTA-4OHcinn). Read More

View Article and Full-Text PDF

Tracking oxidation-induced alterations in fibrin clot formation by NMR-based methods.

Sci Rep 2021 Aug 3;11(1):15691. Epub 2021 Aug 3.

School of Biological Sciences, Nanyang Technological University, Singapore, Singapore.

Plasma fibrinogen is an important coagulation factor and susceptible to post-translational modification by oxidants. We have reported impairment of fibrin polymerization after exposure to hypochlorous acid (HOCl) and increased methionine oxidation of fibrinogen in severely injured trauma patients. Molecular dynamics suggests that methionine oxidation poses a mechanistic link between oxidative stress and coagulation through protofibril lateral aggregation by disruption of AαC domain structures. Read More

View Article and Full-Text PDF