2,050 results match your criteria Australian Academic & Research Libraries[Journal]


Factors associated with spontaneous stone passage in a contemporary cohort of patients presenting with acute ureteric colic. Results from the MIMIC Study (A Multi-centre cohort study evaluating the role of Inflammatory Markers In patients presenting with acute ureteric Colic).

BJU Int 2019 Apr 18. Epub 2019 Apr 18.

British Urology Researchers in Surgical Training (BURST), London, United Kingdom.

Objectives: There is conflicting data on the role of white blood cell count (WBC) and other inflammatory markers in spontaneous stone passage in patients with acute ureteric colic. The aim of the study was to assess the relationship of WBC and other routinely collected inflammatory and clinical markers including stone size, stone position and Medically Expulsive Therapy use (MET) with spontaneous stone passage (SSP) in a large contemporary cohort of patients with acute ureteric colic.

Subjects And Methods: Multi-centre retrospective cohort study coordinated by the British Urology Researchers in Surgical Training (BURST) Research Collaborative at 71 secondary care hospitals across 4 countries (United Kingdom, Republic of Ireland, Australia and New Zealand). Read More

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http://dx.doi.org/10.1111/bju.14777DOI Listing

Mainstreaming human and large carnivore coexistence through institutional collaboration.

Conserv Biol 2019 Apr 18. Epub 2019 Apr 18.

School of Life and Environmental Sciences, Centre for Integrative Ecology, Deakin University, Burwood, Victoria, Australia.

Achieving human-large carnivore coexistence in Human Dominated Landscapes (HDL) is a key challenge for societies globally. This challenge cannot be adequately met with the current sectoral approaches of HDL governance and an academic sector largely dominated by disciplinary silos. In this essay, we urge academia (universities and other research institutions and organisations) to take a more active role in embracing societal challenges around large carnivore conservation in HDL. Read More

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http://dx.doi.org/10.1111/cobi.13334DOI Listing

Paediatric Physiotherapy curriculum: an audit and survey of Australian entry-level Physiotherapy programs.

BMC Med Educ 2019 Apr 16;19(1):109. Epub 2019 Apr 16.

Faculty of Health Sciences and Medicine, Bond Institute of Health and Sport, Bond University, Robina, QLD, Gold Coast, 4226, Australia.

Background: No documented standard or core competencies exist for paediatric curriculum in entry-level physiotherapy programs in Australia. Consequently, extensive variability is thought to exist amongst Australian entry-level physiotherapy programs for preparing physiotherapists to work safely and effectively with children. The purpose of this study was to explore the landscape of paediatric curriculum in Australian entry-level physiotherapy programs and identify the paediatric content being covered, its perceived importance according to university academics who teach paediatrics, the mode of delivery and assessment, and the strengths, weaknesses, barriers and facilitators to implementing paediatric curriculum. Read More

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http://dx.doi.org/10.1186/s12909-019-1540-zDOI Listing

National trends in urinary diversion over the past 20 years: an Australian study.

ANZ J Surg 2019 Apr 15. Epub 2019 Apr 15.

Department of Urology, Westmead Hospital, Sydney, New South Wales, Australia.

Background: To investigate the trends in urinary diversion (UD) in Australia over the past 20 years, to correlate with patient demographics and to compare with international data.

Methods: A retrospective analysis of Medicare Australia data was performed using the relevant Medicare Benefit Schedule procedure codes over the past 20 years. Included diversion procedures were ureterocutaneous, ureterocolonic, intestinal conduit and continent reservoir. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/ans.15134
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http://dx.doi.org/10.1111/ans.15134DOI Listing
April 2019
1 Read

ESCRT-III is necessary for the integrity of the nuclear envelope in micronuclei but is aberrant at ruptured micronuclear envelopes generating damage.

Oncogenesis 2019 Apr 15;8(5):29. Epub 2019 Apr 15.

Department of Chemistry, Centre for Membrane Interactions and Dynamics (CMIAD), Krebs Institute, University of Sheffield, Brook Hill, Sheffield, S3 7HF, United Kingdom.

Micronuclei represent the cellular attempt to compartmentalize DNA to maintain genomic integrity threatened by mitotic errors and genotoxic events. Some micronuclei show aberrant nuclear envelopes (NEs) that collapse, generating damaged DNA that can promote complex genome alterations. However, ruptured micronuclei also provide a pool of cytosolic DNA that can stimulate antitumor immunity, revealing the complexity of micronuclear impact on tumor progression. Read More

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http://www.nature.com/articles/s41389-019-0136-0
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http://dx.doi.org/10.1038/s41389-019-0136-0DOI Listing
April 2019
1 Read

A sense of dread: affect and risk perception in people with schizophrenia during an influenza pandemic.

Australas Psychiatry 2019 Apr 15:1039856219839467. Epub 2019 Apr 15.

Associate Professor and Acting Head, Academic Unit of Psychiatry and Addiction Medicine, Australian National University Medical School, Woden, ACT, and; Clinical Associate Professor, Department of Psychiatry, Royal Melbourne Hospital, Parkville, VIC, and; Director, Research Centre for the Neurosciences of Ageing, Canberra Hospital, Canberra, ACT, Australia.

Objective: To explore the role of affect in risk perception and intention to adopt protective measures against pandemic swine influenza in people with schizophrenia.

Methods: A cross-sectional study was conducted exploring the responses of 71 adults with schizophrenia and 238 adults attending general practice settings without schizophrenia. Participants completed a questionnaire that included items relating to: self-predicted affect (affective forecast) were they to contract swine influenza; perceived risk from swine influenza; and willingness to adopt protective measures against swine influenza. Read More

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http://dx.doi.org/10.1177/1039856219839467DOI Listing
April 2019
1 Read

Language Translation Apps in Health Care Settings: Expert Opinion.

JMIR Mhealth Uhealth 2019 Apr 9;7(4):e11316. Epub 2019 Apr 9.

National Ageing Research Institute, Parkville, Australia.

Background: Currently, over 300 languages are spoken in Australian homes. People without proficient English from non-English speaking countries may not receive equitable care if their health care workers do not speak their primary language. Use of professional interpreters is considered the gold standard; however, for a variety of reasons, it is often limited to key aspects of care such as diagnosis and consent. Read More

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http://dx.doi.org/10.2196/11316DOI Listing

In vivo localization of cortical areas using a 3D computerized atlas of the marmoset brain.

Brain Struct Funct 2019 Apr 8. Epub 2019 Apr 8.

Centre de recherche Cerveau et Cognition (CerCo), Université de Toulouse UPS, CNRS, UMR 5549, CHU Purpan, Pavillon Baudot, BP 25202, 31052, Toulouse Cedex 3, France.

We created a volumetric template of the marmoset (Callithrix jacchus) brain, which enables localization of the cortical areas defined in the Paxinos et al. (The marmoset brain in stereotaxic coordinates. Elsevier Academic Press, Cambridge, 2012) marmoset brain atlas, as well as seven broader cortical regions (occipital, temporal, parietal, prefrontal, motor, limbic, insular), different brain compartments (white matter, gray matter, cerebro-spinal fluid including ventricular spaces), and various other structures (brain stem, cerebellum, olfactory bulb, hippocampus). Read More

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http://link.springer.com/10.1007/s00429-019-01869-x
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http://dx.doi.org/10.1007/s00429-019-01869-xDOI Listing
April 2019
7 Reads

Protocol update and statistical analysis plan for CADENCE-BZ: a randomized clinical trial to assess the efficacy of sodium benzoate as an adjunctive treatment in early psychosis.

Trials 2019 Apr 8;20(1):203. Epub 2019 Apr 8.

Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, Australia.

Background: CADENCE-BZ is a multi-centre, parallel-group, double-blind randomized controlled trial designed to examine the clinical efficacy and safety of an accessible food preservative, sodium benzoate, as an add-on treatment for patients with early psychosis. The original study protocol was published in 2017. Here, we describe the updated protocol along with the Statistical Analysis Plan (SAP) for the CADENCE-BZ trial prior to study completion. Read More

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http://dx.doi.org/10.1186/s13063-019-3232-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454685PMC

Are there interventions that improve breastfeeding and the use of breast milk in late preterm infants?

J Paediatr Child Health 2019 Apr;55(4):477-480

Department of Neonatal Medicine, Women's and Children's Hospital Network, Adelaide, South Australia, Australia.

To answer the clinical question 'Among late preterm infants are there any interventions that improve the rates of breastfeeding and the use of breast milk compared with current practice?'. MEDLINE via Ovid, Embase via Ovid, the Maternity and Infant Care Database and the Cochrane Library were searched for relevant articles. Articles were excluded if they did not discuss specific interventions to improve breastfeeding, for example, if they only commented on factors such as age, race and education. Read More

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http://dx.doi.org/10.1111/jpc.14404DOI Listing
April 2019
1 Read

Prevalence of childhood lead poisoning and respiratory disease associated with lead smelter emissions.

Environ Int 2019 Apr 4;127:340-352. Epub 2019 Apr 4.

Public Health Information Development Unit, Torrens University Australia, Adelaide, SA 5000, Australia.

Background: The city of Port Pirie in South Australia has been a world leading centre for lead and zinc smelting and processing since 1889 that continues to cause contamination of its environment and resident population. This study quantifies the effect of lead and SO emissions from Nyrstar Port Pirie Pty Ltd's smelter on blood lead and respiratory health outcomes, respectively, and establishes what air quality values are required to better protect human health.

Method: Blood lead and emergency department presentation data collected by South Australia Health (SA Health) and lead in air and SO data collected by the South Australian Environment Protection Authority (SAEPA) were obtained and analysed to quantify health outcomes due to smelter emissions in Port Pirie. Read More

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http://dx.doi.org/10.1016/j.envint.2019.01.062DOI Listing

An age- and sex-specific dietary guidelines index is a valid measure of diet quality in an Australian cohort during youth and adulthood.

Nutr Res 2019 Jan 30. Epub 2019 Jan 30.

Menzies Institute for Medical Research, University of Tasmania, Private Bag 23, Hobart, Tasmania, Australia, 7001. Electronic address:

Measuring diet quality over time is important due to health impacts, but to our knowledge, a Dietary Guidelines Index (DGI) with consistent scoring across childhood/adolescence (youth) and adulthood has not been validated. We hypothesized that a DGI that reflected age- and sex-specific guidelines would be a valid measure of diet quality in youth and adulthood. The DGI is based on the 2013 Australian Dietary Guidelines to reflect current understanding of diet quality and comprises 9 indicators, with a maximum score of 100 points. Read More

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http://dx.doi.org/10.1016/j.nutres.2019.01.007DOI Listing
January 2019
2 Reads

'There's more to a person than what's in front of you': Nursing students' experiences of consumer taught mental health education.

Int J Ment Health Nurs 2019 Apr 5. Epub 2019 Apr 5.

Department of Nursing, University of Iceland, Reykjavik, Iceland.

Holistic and person-centred nursing care is commonly regarded as fundamental to nursing practice. These approaches are complementary to recovery which is rapidly becoming the preferred mode of practice within mental health. The willingness and ability of nurses to adopt recovery-oriented practice is essential to services realizing recovery goals. Read More

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http://dx.doi.org/10.1111/inm.12596DOI Listing
April 2019
1 Read

Sperm cryopreservation prior to gonadotoxic treatment: experience of a single academic centre over 4 decades.

Hum Reprod 2019 Apr 5. Epub 2019 Apr 5.

Andrology Department, Concord Hospital, Hospital Road, Concord Hospital, New South Wales 2139, Australia.

Study Question: What is the natural history of outcomes of sperm cryostorage at an Australian tertiary academic centre?

Summary Answer: Cryostorage is feasible in virtually all men facing gonadotoxic therapy but the timing of sperm disposal varies according to the reason for it.

What Is Known Already: Gonadotoxic treatment for cancer or non-cancer diseases damages spermatogenesis and impairs male fertility. Sperm cryopreservation is an established technique to preserve male fertility prior to gonadotoxic treatment. Read More

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http://dx.doi.org/10.1093/humrep/dez026DOI Listing
April 2019
4 Reads

Genetic Structure of IQ, Phonemic Decoding Skill, and Academic Achievement.

Front Genet 2019 18;10:195. Epub 2019 Mar 18.

Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, United Kingdom.

The aim of this study was to examine whether phonemic decoding skill (deficits of which characterize dyslexia) shares genetic and/or environmental covariance with scholastic abilities independent of general intelligence. Non-word reading ability, verbal and non-verbal IQ, and standardized academic achievement (Queensland Core Skills Test; QCST) were measured in Australian twins (up to 876 twin pairs and 80 singleton twins). Multivariate genetic analysis showed the presence of a general genetic factor, likely reflecting crystallized ability, which accounted for 45-76% of phenotypic variance in QCST scores, 62% of variance in Verbal IQ, 23% of variance in Performance IQ, and 19% of variance in phonological reading ability. Read More

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https://www.frontiersin.org/article/10.3389/fgene.2019.00195
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http://dx.doi.org/10.3389/fgene.2019.00195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436069PMC
March 2019
5 Reads

Childhood trauma and the impact of deployment on the development of mental disorder in military males.

Psychol Med 2019 Apr 5:1-9. Epub 2019 Apr 5.

Centre for Traumatic Stress Studies (CTSS), University of Adelaide,Level 1, Helen Mayo North, 30 Frome Road, SA 5000,Australia.

Background: Childhood adversity is associated with mental disorder following military deployment. However, it is unclear how different childhood trauma profiles relate to developing a post-deployment disorder. We investigated childhood trauma prospectively in determining new post-deployment probable disorder. Read More

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http://dx.doi.org/10.1017/S0033291719000655DOI Listing

Integrating physical activity into the primary school curriculum: rationale and study protocol for the "Thinking while Moving in English" cluster randomized controlled trial.

BMC Public Health 2019 Apr 4;19(1):379. Epub 2019 Apr 4.

Priority Research Centre for Physical Activity and Nutrition, University of Newcastle, Callaghan, NSW 2308, Australia.

Background: The current and declining physical activity levels of children is a global concern. Integrating physical activity into the school curriculum may be an effective way not only to improve children's physical activity levels but also enhance educational outcomes. Given the recent national focus in Australia on improving the literacy levels of children in primary school, and an increasing proportion of time spent on explicitly teaching these skills, integrating physical activity into English could be a viable strategy to improve literacy levels and physical activity at the same time. Read More

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http://dx.doi.org/10.1186/s12889-019-6635-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449912PMC

Death of a close friend: Short and long-term impacts on physical, psychological and social well-being.

PLoS One 2019 4;14(4):e0214838. Epub 2019 Apr 4.

ANU Medical School, Academic Unit of General Practice, The Canberra Hospital, Garran, ACT, Australia.

This paper reports the impact of a major life event-death-on the physical, psychological and social well-being of the deceased's close friends. We utilised data from a large longitudinal survey covering a period of 14 years (2002-2015) consisting a cohort of 26,515 individuals in Australia, of whom 9,586 had experienced the death of at least one close friend. This longitudinal cohort dataset comprises responses to the SF-36 (health related quality of life measure) and allowed for analysis of the short and longer-term impacts of bereavement. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214838PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448887PMC
April 2019
1 Read

Effectiveness of regional medical schools in attracting and retaining students for early-career practice in the local area: The James Cook University experience.

Aust J Rural Health 2019 Apr 4. Epub 2019 Apr 4.

College of Medicine and Dentistry, James Cook University, Townsville, Queensland, Australia.

Objective: The regionally based James Cook University medical school in northern Australia has focused its selection processes and curriculum on recruiting, training and graduating doctors to address local workforce needs. This study investigates if James Cook University's regionally based medical school model promotes graduates undertaking internship in local regional hospitals.

Design, Setting & Participants: Cross-sectional survey of final year James Cook University Bachelor of Medicine, Bachelor of Surgery graduates towards the end of the 2016 and 2017 academic years (n = 207; response rate = 58%). Read More

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http://dx.doi.org/10.1111/ajr.12498DOI Listing
April 2019
1 Read

Family needs during critical illness in the Emergency Department: A retrospective factor analysis of data from three countries.

J Clin Nurs 2019 Apr 2. Epub 2019 Apr 2.

Department of Nursing, Chang Gung University of Science and Technology, Taiwan, Republic of China.

Aims And Objectives: Examine underlying factor structure of the Critical Care Family Needs Inventory - Emergency Department (CCFNI-ED) across three countries to identify similarities and differences.

Background: Understanding family needs assists nurses to provide family-centred care to deliver optimal outcomes for critically ill patients and their families in Emergency Departments (EDs).

Design: Retrospective secondary analyses of data collected in three cross-sectional surveys. Read More

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http://dx.doi.org/10.1111/jocn.14857DOI Listing
April 2019
11 Reads
1.233 Impact Factor

Increased demand for amphetamine treatment in rural Australia.

Addict Sci Clin Pract 2019 Apr 1;14(1):13. Epub 2019 Apr 1.

Lives Lived Well, Orange, NSW, Australia.

Background: A substantial increase in substance treatment episodes for methamphetamine problems suggests characteristics of the treatment population could have changed and that targeted treatment programs are required. To determine who methamphetamine treatment should be designed for this study has two aims. First, to empirically describe changes in amphetamine treatment presentations to a rural NSW drug and alcohol treatment agency over time. Read More

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http://dx.doi.org/10.1186/s13722-019-0144-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442410PMC

Sensitivity of a Preclinical Alzheimer's Cognitive Composite (PACC) to amyloid β load in preclinical Alzheimer's disease.

J Clin Exp Neuropsychol 2019 Mar 29:1-10. Epub 2019 Mar 29.

a The Florey Institute of Neuroscience and Mental Health , The University of Melbourne , Melbourne , VIC , Australia.

Introduction: Preclinical Alzheimer's disease (AD) is characterized by amyloid-related cognitive decline. Reduction in this decline is used to determine the efficacy of drug therapies designed to forestall the disease in preclinical AD clinical trials, measured by a Preclinical Alzheimer's Cognitive Composite (PACC). Most studies estimate rates of cognitive change by comparing cognitively normal (CN) older adults with abnormally high beta-amyloid (Aβ+) to those with low levels (Aβ-). Read More

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http://dx.doi.org/10.1080/13803395.2019.1593949DOI Listing
March 2019
2 Reads

The geography of a controversial diagnosis: A bibliographic analysis of published academic perspectives on 'paediatric bipolar disorder'.

Clin Child Psychol Psychiatry 2019 Mar 25:1359104519836700. Epub 2019 Mar 25.

2 College of Medicine and Public Health, Flinders University, Australia.

Background: The hypothesis that bipolar disorder presents before puberty with atypical mania has proved to be controversial. Published academic perspectives on the validity of Paediatric Bipolar Disorder (PBD) appear to vary between the United States and the rest of the world.

Methods: We examined the perspectives of articles citing four seminal articles. Read More

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http://dx.doi.org/10.1177/1359104519836700DOI Listing
March 2019
1 Read

The influence of complexity: a bibliometric analysis of complexity science in healthcare.

BMJ Open 2019 Mar 23;9(3):e027308. Epub 2019 Mar 23.

Australian Institute of Health Innovation, Macquarie University, Sydney, NSW, Australia.

Objectives: To analyse trends in the academic literature applying complexity science to healthcare, focusing specifically on bibliometric characteristics and indicators of influence.

Design: This study reports a bibliometric analysis via a systematic search of the academic literature applying complexity science to healthcare.

Method: A search of four academic databases was performed on 19 April 2018. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-027308DOI Listing
March 2019
1 Read

Mental Health Care for Service Members and Their Families Across the Globe.

Mil Med 2019 Mar;184(Supplement_1):418-425

Psychological Health Center of Excellence, Defense Health Agency (J-9), 1335 East-West Hwy., Ste. 900, Silver Spring, MD.

The U.S. Defense Department partnered with the International Initiative for Mental Health Leadership on effective leadership and operational practices for delivery of mental health (MH) as well as addiction services throughout the world for Service Members (SM) and beneficiaries. Read More

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http://dx.doi.org/10.1093/milmed/usy324DOI Listing
March 2019
1 Read

Cross-sectional and prospective relationships of passive and mentally active sedentary behaviours and physical activity with depression.

Br J Psychiatry 2019 Mar 21:1-7. Epub 2019 Mar 21.

Associate Professor, Obesity Center, Academic Specialist Center, Stockholm Health Services; and Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet,Sweden.

Background: Sedentary behaviour can be associated with poor mental health, but it remains unclear whether all types of sedentary behaviour have equivalent detrimental effects.AimsTo model the potential impact on depression of replacing passive with mentally active sedentary behaviours and with light and moderate-to-vigorous physical activity. An additional aim was to explore these relationships by self-report data and clinician diagnoses of depression. Read More

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http://dx.doi.org/10.1192/bjp.2019.60DOI Listing
March 2019
1 Read
7.991 Impact Factor

A critical integrative review of complementary medicine education research: key issues and empirical gaps.

BMC Complement Altern Med 2019 Mar 20;19(1):73. Epub 2019 Mar 20.

Distinguished Professor of Public Health, ARC Professorial Future Fellow and Director of the Australian Research Centre in Complementary and Integrative Medicine (ARCCIM), Faculty of Health, University of Technology Ultimo, Sydney, NSW, Australia.

Background: Complementary Medicine (CM) continues to thrive across many countries. Closely related to the continuing popularity of CM has been an increased number of enrolments at CM education institutions across the public and private tertiary sectors. Despite the popularity of CM across the globe and growth in CM education/education providers, to date, there has been no critical review of peer-reviewed research examining CM education undertaken. Read More

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http://dx.doi.org/10.1186/s12906-019-2466-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427897PMC

A metagenomic study of DNA viruses from samples of local varieties of common bean in Kenya.

PeerJ 2019 15;7:e6465. Epub 2019 Mar 15.

School of Molecular Sciences and Australian Research Council Centre of Excellence in Plant Energy Biology, The University of Western Australia, Crawley, WA, Australia.

Common bean (.) is the primary source of protein and nutrients in the majority of households in sub-Saharan Africa. However, pests and viral diseases are key drivers in the reduction of bean production. Read More

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http://dx.doi.org/10.7717/peerj.6465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422016PMC

Ionic liquids and protein folding-old tricks for new solvents.

Biophys Rev 2019 Apr 19;11(2):209-225. Epub 2019 Mar 19.

Institute for Protein Research, Osaka University, 3-1-Yamada-oka, Suita, Osaka, 565-0871, Japan.

One important aspect of the green chemistry revolution has been the use of ionic liquids as the solvent in liquid-phase enzymatic catalysis. An essential requirement for protein enzyme function is the correct folding of the polypeptide chain into its functional "native" state. Quantitative assessment of protein structure may be carried out either empirically, or by using model-based characterization procedures, in which the parameters are defined in terms of a standard reference state. Read More

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http://dx.doi.org/10.1007/s12551-019-00509-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441443PMC

Regular Sunscreen Use and Risk of Mortality: Long-Term Follow-up of a Skin Cancer Prevention Trial.

Am J Prev Med 2019 May 16;56(5):742-746. Epub 2019 Mar 16.

School of Exercise and Nutrition Sciences, Queensland University of Technology, Brisbane, Australia. Electronic address:

Introduction: Sunscreen is widely used to protect the skin from harmful effects of sun exposure. However, there are concerns that sunscreens may negatively affect overall health. Evidence of the general safety of long-term regular sunscreen use is therefore needed. Read More

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http://dx.doi.org/10.1016/j.amepre.2018.11.025DOI Listing

Cross-sectional analysis of veterinary student coping strategies and stigma in seeking psychological help.

Vet Rec 2019 Mar 16. Epub 2019 Mar 16.

School of Animal and Veterinary Sciences, University of Adelaide, Roseworthy, South Australia, Australia.

Veterinary education can result in high levels of academic stressors for students. Students are also susceptible to non-academic stressors, including relationship issues and financial concerns. These can all result in mental ill health, which may impair the student's ability to complete their studies and go on to a successful professional career. Read More

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http://dx.doi.org/10.1136/vr.105042DOI Listing

Computerized cognitive training for older adults at higher dementia risk due to diabetes: findings from a randomized controlled trial.

J Gerontol A Biol Sci Med Sci 2019 Mar 14. Epub 2019 Mar 14.

Joseph Sagol Neuroscience Center, Sheba Medical Center, Israel.

Background: To evaluate the effects of adaptive and tailored computerized cognitive training [CCT] on cognition and disease self-management in older adults with diabetes.

Methods: Single-blind trial. Eighty-four community-dwelling older adults with diabetes were randomized into a tailored and adaptive computerized cognitive training [TA-CCT] or a generic, non-tailored or adaptive CCT condition [GCCT]. Read More

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https://academic.oup.com/biomedgerontology/advance-article/d
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http://dx.doi.org/10.1093/gerona/glz073DOI Listing
March 2019
5 Reads

Postoperative critical care and high-acuity care provision in the United Kingdom, Australia, and New Zealand.

Br J Anaesth 2019 Apr 8;122(4):460-469. Epub 2019 Feb 8.

UCL/UCLH Surgical Outcomes Research Centre, Centre for Perioperative Medicine, Department for Targeted Intervention, Division of Surgery and Interventional Science, University College London, London, UK; Health Services Research Centre, National Institute of Academic Anaesthesia, Royal College of Anaesthetists, London, UK.

Background: Decisions to admit high-risk postoperative patients to critical care may be affected by resource availability. We aimed to quantify adult ICU/high-dependency unit (ICU/HDU) capacity in hospitals from the UK, Australia, and New Zealand (NZ), and to identify and describe additional 'high-acuity' beds capable of managing high-risk patients outside the ICU/HDU environment.

Methods: We used a modified Delphi consensus method to design a survey that was disseminated via investigator networks in the UK, Australia, and NZ. Read More

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http://dx.doi.org/10.1016/j.bja.2018.12.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435907PMC
April 2019
1 Read
4.853 Impact Factor

Amyloid β Induces Early Changes in the Ribosomal Machinery, Cytoskeletal Organization and Oxidative Phosphorylation in Retinal Photoreceptor Cells.

Front Mol Neurosci 2019 22;12:24. Epub 2019 Feb 22.

Department of Molecular Sciences, Faculty of Science and Engineering, Macquarie University, Sydney, NSW, Australia.

Amyloid β (Aβ) accumulation and its aggregation is characteristic molecular feature of the development of Alzheimer's disease (AD). More recently, Aβ has been suggested to be associated with retinal pathology associated with AD, glaucoma and drusen deposits in age related macular degeneration (AMD). In this study, we investigated the proteins and biochemical networks that are affected by Aβ in the 661 W photoreceptor cells in culture. Read More

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http://dx.doi.org/10.3389/fnmol.2019.00024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395395PMC
February 2019

Living Guidelines for Absolute Cardiovascular Disease Risk Assessment and Management.

Heart Lung Circ 2019 Feb 11. Epub 2019 Feb 11.

National Centre for Epidemiology and Population Health, Research School of Population Health, The Australian National University, Canberra, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.hlc.2019.01.014DOI Listing
February 2019

A systematic review of scabies transmission models and data to evaluate the cost-effectiveness of scabies interventions.

PLoS Negl Trop Dis 2019 03 8;13(3):e0007182. Epub 2019 Mar 8.

Centre for Health Economics Research and Evaluation, University of Technology Sydney, Sydney, Australia.

Background: Scabies is a common dermatological condition, affecting more than 130 million people at any time. To evaluate and/or predict the effectiveness and cost-effectiveness of scabies interventions, disease transmission modelling can be used.

Objective: To review published scabies models and data to inform the design of a comprehensive scabies transmission modelling framework to evaluate the cost-effectiveness of scabies interventions. Read More

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http://dx.plos.org/10.1371/journal.pntd.0007182
Publisher Site
http://dx.doi.org/10.1371/journal.pntd.0007182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426261PMC
March 2019
11 Reads

Ultrahigh-Performance Liquid Chromatography Tandem Mass Spectrometry with Electrospray Ionization Quantification of Tryptophan Metabolites and Markers of Gut Health in Serum and Plasma-Application to Clinical and Epidemiology Cohorts.

Anal Chem 2019 Apr 25;91(8):5207-5216. Epub 2019 Mar 25.

Division of Integrative Systems and Digestive Medicine, Department of Surgery and Cancer , Imperial College London , Sir Alexander Fleming Building, South Kensington Campus , London SW7 2AZ , United Kingdom.

A targeted ultrahigh-performance liquid chromatography tandem mass spectrometry with electrospray ionization (UHPLC-ESI-MS/MS) method has been developed for the quantification of tryptophan and its downstream metabolites from the kynurenine and serotonin pathways. The assay coverage also includes markers of gut health and inflammation, including citrulline and neopterin. The method was designed in 96-well plate format for application in multiday, multiplate clinical and epidemiology population studies. Read More

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http://dx.doi.org/10.1021/acs.analchem.8b05884DOI Listing
April 2019
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Post-Ebola psychosocial experiences and coping mechanisms among Ebola survivors: a systematic review.

Trop Med Int Health 2019 Mar 7. Epub 2019 Mar 7.

Australian Research Centre in Complementary and Integrative Medicine (ARCCIM), Faculty of Health, University of Technology Sydney, Sydney, NSW, Australia.

Objective: A myriad of physical and psychosocial sequelae have been reported among Ebola survivors from previous Ebola virus disease (EVD) outbreaks, including the most recent in West Africa. This review examines the various forms of psychological distress experienced by EVD survivors, family and community reactions to EVD survivors and EVD survivors' coping mechanisms.

Methods: We conducted a literature search of original articles employing Medline (Ovid), PubMed, Web of Science, Scopus, CINAHL, EBSCO host academic search complete, PsycINFO (EBSCO) and Embase databases. Read More

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http://dx.doi.org/10.1111/tmi.13226DOI Listing
March 2019
36 Reads
2.541 Impact Factor

A transformative translational change programme to introduce genomics into healthcare: a complexity and implementation science study protocol.

BMJ Open 2019 Mar 5;9(3):e024681. Epub 2019 Mar 5.

Melbourne Genomics Health Alliance, Walter and Eliza Hall Institute, Melbourne, Victoria, Australia.

Introduction: Translating scientific advances in genomic medicine into evidence-based clinical practice is challenging. Studying the natural translation of genomics into 'early-adopting' health system sectors is essential. We will (a) examine 29 health systems (Australian and Melbourne Genomics Health Alliance flagships) integrating genomics into practice and (b) combine this learning to co-design and test an evidence-based generalisable toolkit for translating genomics into healthcare. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-024681DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429849PMC

Patient Perceptions of CT Imaging in a Diverse Patient Sample.

J Am Coll Radiol 2019 Mar 1. Epub 2019 Mar 1.

University of Colorado Denver, School of Medicine, Department of Radiology, Aurora, Colorado.

Objective: To describe patient perceptions related to CT and evaluate variation related to patient sociodemographic characteristics.

Methods: Institutional review board-approved survey of adult patients undergoing outpatient CT at a large academic hospital administered May 2016 to March 2017. The survey included questions about participant demographic and socioeconomic characteristics as well as scales that addressed five perceptual constructs related to their CT examination: knowledge, benefits, barriers, expectations, and trust. Read More

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http://dx.doi.org/10.1016/j.jacr.2018.12.027DOI Listing
March 2019
3 Reads

Just how bad does it have to be? Industry and academic assessors' experiences of failing to fail - A descriptive study.

Nurse Educ Today 2019 May 23;76:206-215. Epub 2019 Feb 23.

Menzies Health Institute Queensland, Griffith University, Nathan, Qld 4111, Australia; The University of Queensland, School of Nursing, Midwifery and Social Work, Tri Woolloongabba, Qld 4102, Australia; Princess Alexandra Hospital, Department of Emergency Medicine, Ipswich Rd, Wooloongabba, Qld 4102, Australia.

Background: Failing to fail nursing students in clinical assessments is an internationally acknowledged issue that necessitates thorough examination. Despite the gravity of 'mis-grading' nursing students, current research exploring this subject is limited. Understanding the experiences of assessors when faced with an underperforming student may help illuminate some of the broad issues associated with failure to fail. Read More

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http://dx.doi.org/10.1016/j.nedt.2019.02.011DOI Listing

ASSESSING THE ACCURACY OF A LARGE OBSERVATIONAL REGISTRY OF NEOVASCULAR AGE-RELATED MACULAR DEGENERATION.

Retina 2019 Feb 25. Epub 2019 Feb 25.

Discipline of Ophthalmology, The University of Sydney, Save Sight Institute, Sydney Medical School, Sydney, New South Wales, Australia.

Purpose: To evaluate the accuracy of an observational database that tracks real-world treatment outcomes for neovascular age-related macular degeneration.

Methods: We audited 245 randomly sampled eyes from 189 patients with 3,356 visits from 11 doctors in the Fight Retinal Blindness!

Database: Sex, birth year, previous treatments received, treatment, and visual acuity were validated against the clinical notes. Error rates, the proportion of missed visits (the number of visits present in the patient record but not entered into Fight Retinal Blindness!), the level of agreement using Cohen's kappa (κ) and intraclass correlation coefficients, and positive and negative predictive values were calculated. Read More

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http://dx.doi.org/10.1097/IAE.0000000000002485DOI Listing
February 2019
2 Reads

Comparison of emergency department time performance between a Canadian and an Australian academic tertiary hospital.

Emerg Med Australas 2019 Feb 27. Epub 2019 Feb 27.

Austin Health, Melbourne, Victoria, Australia.

Objective: To compare performance and factors predicting failure to reach Ontario and Australian government time targets between a Canadian (Sunnybrook Hospital) and an Australian (Austin Health) academic tertiary-level hospitals in 2012, and to assess for change of factors and performance in 2016 between the same hospitals.

Methods: This was a retrospective, observational study of patient administrative data in two calendar years. The main outcome measure was reaching Ontario and Australian ED time targets for admissions, high and low urgency discharges. Read More

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http://doi.wiley.com/10.1111/1742-6723.13247
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http://dx.doi.org/10.1111/1742-6723.13247DOI Listing
February 2019
11 Reads

Human health in relation to exposure to solar ultraviolet radiation under changing stratospheric ozone and climate.

Photochem Photobiol Sci 2019 Mar 27;18(3):641-680. Epub 2019 Feb 27.

QIMR Berghofer Institute of Medical Research, Herston, Brisbane, Australia and School of Public Health, University of Queensland, Australia.

The Montreal Protocol has limited increases in the UV-B (280-315 nm) radiation reaching the Earth's surface as a result of depletion of stratospheric ozone. Nevertheless, the incidence of skin cancers continues to increase in most light-skinned populations, probably due mainly to risky sun exposure behaviour. In locations with strong sun protection programs of long duration, incidence is now reducing in younger age groups. Read More

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http://dx.doi.org/10.1039/c8pp90060dDOI Listing
March 2019
1 Read

Higher diet quality in university students is associated with higher academic achievement: a cross-sectional study.

J Hum Nutr Diet 2019 Jun 27;32(3):321-328. Epub 2019 Feb 27.

School of Health Sciences, Faculty of Health and Medicine, and Priority Research Centre for Physical Activity and Nutrition, University of Newcastle, Callaghan, NSW, Australia.

Background: Unhealthy diets are typical of university students and the effects may be wider reaching than health. The present study aimed to describe the association between dietary intake and academic achievement in a sample of Australian university students.

Methods: A cross-sectional analysis of data from an online survey of 278 students from the University of Newcastle (UON), Australia [mean (SD) age 26. Read More

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http://dx.doi.org/10.1111/jhn.12632DOI Listing

Subjective wellbeing at different spatial scales for individuals satisfied and dissatisfied with life.

PeerJ 2019 21;7:e6502. Epub 2019 Feb 21.

College of Business, Law & Governance, James Cook University of North Queensland, Townsville, QLD, Australia.

Indicators that attempt to gauge wellbeing have been created and used at multiple spatial scales around the world. The most commonly used indicators are at the national level to enable international comparisons. When analyzing subjective life satisfaction (LS), an aspect of wellbeing, at multiple spatial scales in Australia, variables (drawn from environmental, social, and economic domains) that are significantly correlated to LS at smaller scales become less significant at larger sub-national scales. Read More

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http://dx.doi.org/10.7717/peerj.6502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387756PMC
February 2019

"Better health in the bush": why we urgently need a national rural and remote health strategy.

Med J Aust 2019 Mar 24;210(5):202-203.e1. Epub 2019 Feb 24.

School of Rural Health, Monash University, Bendigo, VIC.

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http://dx.doi.org/10.5694/mja2.50041DOI Listing

Anatomical Sciences in Chiropractic Education: A Survey of Chiropractic Programs in Australia.

Anat Sci Educ 2019 Feb 21. Epub 2019 Feb 21.

Department of Anatomy, School of Medical Sciences, Faculty of Medicine, The University of New South Wales, Sydney, New South Wales, Australia.

Human anatomy knowledge is a core requirement for all health care clinicians. There is a paucity of information relating to anatomy content and delivery in Australian chiropractic programs. The aim of this study was to describe anatomy teaching in Australian chiropractic programs, utilizing a survey which was distributed to all four programs, requesting information on: anatomy program structure, delivery methods, assessment, teaching resources, and academic staff profile at their institution. Read More

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http://dx.doi.org/10.1002/ase.1871DOI Listing
February 2019