4,604 results match your criteria Australasian Physical & Engineering Sciences In Medicine[Journal]

Patient perceptions of surgical telehealth consultations during the COVID 19 pandemic in Australia: Lessons for future implementation.

ANZ J Surg 2021 Jun 21. Epub 2021 Jun 21.

Surgical Services, John Hunter Hospital, Newcastle, New South Wales, Australia.

Introduction: Prior studies of telehealth report high levels of patient satisfaction, but within carefully selected clinical scenarios. The COVID-19 pandemic led to telehealth replacing face-to-face care for many surgical consultations across a variety of situations. More evidence is needed regarding patient perceptions of telehealth in surgery, in particular, exploring barriers and facilitators associated with its sustained implementation beyond the pandemic. Read More

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Radiation oncology training in Singapore - A non-Australasian RANZCR training site.

J Med Imaging Radiat Oncol 2021 Jun 19. Epub 2021 Jun 19.

Radiation Oncology Centre, Mount Elizabeth Novena Hospital, Singapore City, Singapore.

The Radiation Oncology Department at The National Cancer Institute, Singapore (NCIS) and the Royal Australian and New Zealand College of Radiology (RANZCR) has had a well-established relationship that began as a partnership to grow a pool of local radiation oncologists to meet a nation's demand for radiotherapy services. This journey has surpassed its initial aims and now has produced a generation of radiation oncologists leading a national cancer institute. We recount the history and progress of this partnership here, as well as the unique success of its product; the only RANZCR-accredited radiation oncology training site outside of Australia and New Zealand since 2002. Read More

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Variation in Intact Abdominal Aortic Aneurysm Repair Outcomes by Country: Analysis of International Consortium of Vascular Registries 2010 - 2016.

Eur J Vasc Endovasc Surg 2021 Jun 15. Epub 2021 Jun 15.

Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.

Objective: Outcomes for intact abdominal aortic aneurysm (AAA) repair vary over time and by healthcare system, country, and surgeon. The aim of this study was to analyse peri-operative mortality for intact AAA repair in 11 countries over time and compare outcomes by gender, age, and geographical location.

Methods: Prospective data on primary repair of intact AAA were collected from 11 countries through the International Consortium of Vascular Registries (ICVR) and analysed for two time periods, 2010 - 2013 and 2014 - 2016. Read More

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The impact of COVID-19 pandemic on vascular registries and clinical trials.

Semin Vasc Surg 2021 Jun 21;34(2):28-36. Epub 2021 May 21.

Patient Safety Organization, Society for Vascular Surgery, Rosemont, IL; Indiana University, 1801 N Senate Boulevard, D-3500, Indianapolis, IN 46202. Electronic address:

Quality improvement programs and clinical trial research experienced disruption due to the coronavirus disease 2019 (COVID-19) pandemic. Vascular registries showed an immediate impact with significant declines in second-quarter vascular procedure volumes witnessed across Europe and the United States. To better understand the magnitude and impact of the pandemic, organizations and study groups sent grass roots surveys to vascular specialists for needs assessment. Read More

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Glycaemic outcomes in Australasian children and adults with Type 1 Diabetes: failure to meet targets across the age spectrum.

Intern Med J 2021 Jun 18. Epub 2021 Jun 18.

Department of Endocrinology and Diabetes, Perth Children's Hospital, Perth, Australia.

Background: The goal of therapy in Type 1 diabetes (T1D) is to achieve optimal glycaemic targets and reduce complications. Robust data representing glycaemic outcomes across the lifespan are lacking in Australasia.

Aims: To examine contemporary glycaemic outcomes and rate of use of diabetes technologies in Australasian people with T1D. Read More

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Seeking Approval: International Higher Education Students' Experiences of Applying for Human Research Ethics Clearance in Australia.

J Acad Ethics 2021 Jun 11:1-16. Epub 2021 Jun 11.

Australasian Human Research Ethics Consultancy Services, University of Western Australia, Perth, Australia.

University human research ethics application procedures can be complicated and daunting, especially for international students unfamiliar with the process and the language. We conducted focus groups and interviews with four research higher degree and 21 Master's coursework international students at an Australian university to gain their views on the human ethics application process. We found the most important influences on their experience were: the time it took to do an application; support from supervisors, peers and others; their own language skills; and their lack of familiarity with research ethics procedures. Read More

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Advancing leadership in Australasian emergency medicine: Taking stock and looking ahead.

Emerg Med Australas 2021 Jun 15. Epub 2021 Jun 15.

Australasian College for Emergency Medicine, Melbourne, Victoria, Australia.

Since 2018, the Australasian College for Emergency Medicine has collaborated with the Swinburne University of Technology on a research project to understand and enhance the leadership capacity of emergency physicians, beginning with Australasian Directors of Emergency Medicine (DEMs). Over the last 3 years, this research programme has revealed the complexity of leadership in emergency medicine, illuminating the strengths and limitations of extant research and suggesting promising new directions for emergency medicine leadership and leadership development research. This programme has also shed new light on the knowledge, skills and abilities that DEMs need to develop to catalyse change in the systems where DEMs practice both medicine and leadership. Read More

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Elective abdominal wall hernia repair surgical mortality-A systematic review of the literature and peer review of mortality in Australia.

ANZ J Surg 2021 Jun 14. Epub 2021 Jun 14.

Department of Surgery, The University of Adelaide, The Queen Elizabeth Hospital, Adelaide, South Australia, Australia.

Background: This study systematically reviewed the literature regarding perioperative mortality in human adults undergoing elective surgical abdominal wall hernia repair, including an audit of the Royal Australasian College of Surgeons (RACS) Australian and New Zealand Audit of Surgical Mortality (ANZASM) database.

Methods: A systematic review was conducted in accordance with PRISMA guidelines for the reporting of systematic reviews and meta-analysis of observational studies. Cochrane Library, PubMed, MEDLINE and Embase database searches and data extraction were conducted from June 1979 to October 2019. Read More

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An Evaluation of Gaming-Related Harms in Relation to Gaming Disorder and Loot Box Involvement.

Int J Ment Health Addict 2021 Jun 7:1-16. Epub 2021 Jun 7.

College of Education, Psychology and Social Work, Flinders University, Adelaide, Australia.

The specific nature of harm and functional impairment in the context of gaming disorder (GD) has received limited attention. In this study, we present one of the first concerted attempts to measure the types and degree of harm experienced by people displaying signs of problem gaming. Attempts were made to assess the extent to which types of harm were attributable to gaming as opposed to other factors. Read More

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One small step: starting a career in surgical research during COVID-19.

ANZ J Surg 2021 06;91(6):1059-1060

University of Adelaide, Discipline of Surgery, The Queen Elizabeth Hospital, Adelaide, South Australia, Australia.

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ANZ Journal of Surgery: soon to make the shift from print to digital publishing.

ANZ J Surg 2021 06;91(6):1051

Royal Australasian College of Surgeons, Melbourne, Victoria, Australia.

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Emergency clinicians' knowledge, preparedness and experiences of managing COVID-19 during the 2020 global pandemic in Australian healthcare settings.

Australas Emerg Care 2021 Mar 27. Epub 2021 Mar 27.

Marie Bashir Institute for Infectious Diseases and Biosecurity, University of Sydney, Camperdown, NSW, Australia; Susan Wakil School of Nursing and Midwifery, Faculty of Medicine and Health, University of Sydney, Camperdown, NSW, Australia; New South Wales Biocontainment Centre and Department of Infectious Diseases and Sexual Health, Westmead Hospital, Western Sydney Local Health District, Westmead, NSW, Australia; Nursing, Midwifery and Clinical Governance Directorate, Western Sydney Local Health District, Westmead, NSW, Australia. Electronic address:

Background: Emergency clinicians have a crucial role during public health emergencies and have been at the frontline during the COVID-19 pandemic. This study examined the knowledge, preparedness and experiences of Australian emergency nurses, emergency physicians and paramedics in managing COVID-19.

Methods: A voluntary cross-sectional study of members of the College of Emergency Nursing Australasia, the Australasian College for Emergency Medicine, and the Australasian College of Paramedicine was conducted using an online survey (June-September 2020). Read More

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Far eastern curlew and whimbrel prefer flying low - wind support and good visibility appear only secondary factors in determining migratory flight altitude.

Mov Ecol 2021 Jun 13;9(1):32. Epub 2021 Jun 13.

Centre for Integrative Ecology, School of Life and Environmental Science, Deakin University, Geelong, Victoria, Australia.

Background: In-flight conditions are hypothesized to influence the timing and success of long-distance migration. Wind assistance and thermal uplift are thought to reduce the energetic costs of flight, humidity, air pressure and temperature may affect the migrants' water balance, and clouds may impede navigation. Recent advances in animal-borne long-distance tracking enable evaluating the importance of these factors in determining animals' flight altitude. Read More

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Evaluation of the utility of early routine computed tomography angiography in subarachnoid hemorrhage patient outcomes.

J Clin Neurosci 2021 Jul 10;89:133-138. Epub 2021 May 10.

Neurosurgical Service, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. Electronic address:

Objectives: The role of an early CTA approach in neurologically stable patients with nontraumatic SAH has not been assessed. This study explored the use of CTA in clinically stable SAH patients to pre-emptively identify cerebral vasospasm, to evaluate whether this approach is associated with improved clinical outcomes.

Methods: We conducted a retrospective chart review of SAH patients presenting between July 2007 and December 2016 in a single academic center. Read More

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Vulval lichen sclerosus: An Australasian management consensus.

Australas J Dermatol 2021 Jun 12. Epub 2021 Jun 12.

Northern Clinical School, The University of Sydney, Camperdown, New South Wales, Australia.

Background/objectives: Vulval lichen sclerosus (VLS) is a chronic inflammatory skin condition predominantly affecting the anogenital region in women and children. To date, there is lack of agreement amongst experts on a severity scale to aid assessment, research and treatment stratification on VLS. Furthermore, literature on best practice for long-term management of VLS is lacking. Read More

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Infection related mortality in adults and children undergoing allogeneic hematopoietic cell transplantation: An Australian registry report.

Transplant Cell Ther 2021 Jun 7. Epub 2021 Jun 7.

National Centre for Infection in Cancer, Peter MacCallum Cancer Centre, Melbourne, Australia; Department of Infectious Diseases, Peter MacCallum Cancer Centre, Melbourne, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Australia.

Background: Infection related mortality (IRM) is the most common non-relapse mortality reported post allogeneic hematopoietic cell transplantation (HCT). Information on the incidence and timing of specific infective organisms and the risk factors for IRM is essential to developing prevention strategies.

Objective: This report provides the first account of IRM in adults and children undergoing HCT in Australia. Read More

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Personalizing First-Line Systemic Therapy in Metastatic Colorectal Cancer: Is There a Role for Initial Low-Intensity Therapy in 2021 and Beyond? A Perspective From Members of the Australasian Gastrointestinal Trials Group.

Clin Colorectal Cancer 2021 May 11. Epub 2021 May 11.

Department of Medical Oncology, Royal Brisbane Hospital, Herston, Queensland, Australia.

Palliative chemotherapy is the cornerstone of treatment for the majority of patients with metastatic colorectal cancer, with the aim of increasing length and quality of life. Although guidelines outline the available treatment options in the first line, they provide limited guidance on choice and intensity of the chemotherapy backbone. Data from the TRIBE and TRIBE2 studies confirm a survival benefit with triplet FOLFOXIRI and bevacizumab, and this is a preferred option for younger patients with good performance status able to tolerate it. Read More

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Improving the safety of distracted pedestrians with in-ground flashing lights. A railway crossing field study.

J Safety Res 2021 06 30;77:170-181. Epub 2021 Mar 30.

Queensland University of Technology (QUT), School of Optometry and Vision Science, Australia.

Introduction: Current signage at intersections is designed for attentive pedestrians who are looking ahead. Such signage may not be sufficient when distracted by smartphones. Illuminated in-ground LED lights at crossings are an innovative solution to alert distracted pedestrians. Read More

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Recent aspects on epidemiology, clinical disease, and genetic diversity of Toxoplasma gondii infections in Australasian marsupials.

Parasit Vectors 2021 Jun 5;14(1):301. Epub 2021 Jun 5.

Molecular Parasitology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20895, USA.

Background: Toxoplasma gondii infections are common in humans and animals worldwide. Among all intermediate hosts of T. gondii, captive marsupials from Australia and New Zealand are highly susceptible to clinical toxoplasmosis. Read More

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The impact of different responses to negative body talk on body satisfaction, shame, and future fat talk likelihood: A UK sample.

Body Image 2021 Jun 1;38:325-333. Epub 2021 Jun 1.

School of Psychology, Counselling, and Psychotherapy, The Cairnmillar Institute, Australia. Electronic address:

A recent online experiment found that, following a negative body talk induction task, receiving a response of ignoring the comment, compared with reassuring, reciprocating, and challenging, led to worse body satisfaction and socio-emotional outcomes for Australian women. The current online study aimed to replicate and extend this study by examining the effects of these four negative body talk responses on body satisfaction, shame, and future negative body talk likelihood in UK-based women. Participants (N = 156, M = 25. Read More

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Implementation of 3D conformal radiotherapy technology at the National Cancer Centre Mongolia: A successful Asia-Pacific collaborative initiative.

J Med Imaging Radiat Oncol 2021 Jun 4. Epub 2021 Jun 4.

Canterbury Regional Cancer and Haematology Service, Christchurch Hospital, Christchurch, New Zealand.

Introduction: Mongolia has a population of 3.3 million and is classified by the WHO as a lower middle-income country. Cancer is now a major public health issue and one of the leading causes of mortality. Read More

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Evidence-based update on Australasian pharmaceutical prescribing approaches for recurrent vulvovaginal candidiasis.

Aust N Z J Obstet Gynaecol 2021 Jun 3. Epub 2021 Jun 3.

School of Pharmacy and Medical Sciences, Griffith University, Gold Coast, Queensland, Australia.

Recurrent vulvovaginal candidiasis (RVVC) is a subtype of vulvovaginal candidiasis, with debilitating effects on physical and emotional well-being affecting up to 10% of Australian women. Current evidence suggests that the induction and maintenance approach for RVVC is not particularly effective with post-treatment relapse rates as high as 57%. Frequently accessed Australasian RVVC prescribing resources and guidelines were examined showing a variety of adaptations of current evidence-based induction and maintenance therapies, making it difficult to select best treatment in clinical practice. Read More

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A Blue-Enriched, Increased Intensity Light Intervention to Improve Alertness and Performance in Rotating Night Shift Workers in an Operational Setting.

Nat Sci Sleep 2021 24;13:647-657. Epub 2021 May 24.

Turner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Melbourne, Victoria, Australia.

Purpose: This study examined the efficacy of a lighting intervention that increased both light intensity and short-wavelength (blue) light content to improve alertness, performance and mood in night shift workers in a chemical plant.

Patients And Methods: During rostered night shifts, 28 workers (46.0±10. Read More

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Captopril, a Renin-Angiotensin System Inhibitor, Attenuates Features of Tumor Invasion and Down-Regulates C-Myc Expression in a Mouse Model of Colorectal Cancer Liver Metastasis.

Cancers (Basel) 2021 May 31;13(11). Epub 2021 May 31.

Department of Surgery, Austin Health Precinct, The University of Melbourne, Austin Health, Lance Townsend Building, Level 8, 145 Studley Road, Heidelberg, VIC 3084, Australia.

(1) Background: Recent clinical and experimental data suggests that the liver's regenerative response following partial hepatectomy can stimulate tumor recurrence in the liver remnant. The Wnt/β-catenin pathway plays important roles in both colorectal cancer carcinogenesis and liver regeneration. Studies have shown that the Wnt/β-catenin pathway regulates multiple renin-angiotensin system (RAS) genes, whilst RAS inhibition (RASi) reduces tumor burden and progression. Read More

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NADomics: Measuring NAD and Related Metabolites Using Liquid Chromatography Mass Spectrometry.

Life (Basel) 2021 May 31;11(6). Epub 2021 May 31.

School of Medical Sciences, University of New South Wales, Sydney, NSW 2052, Australia.

Nicotinamide adenine dinucleotide (NAD) and its metabolome (NADome) play important roles in preserving cellular homeostasis. Altered levels of the NADome may represent a likely indicator of poor metabolic function. Accurate measurement of the NADome is crucial for biochemical research and developing interventions for ageing and neurodegenerative diseases. Read More

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Methodical Design of Viral Vaccines Based on Avant-Garde Nanocarriers: A Multi-Domain Narrative Review.

Biomedicines 2021 May 6;9(5). Epub 2021 May 6.

Supreme NanoBiotics Co. Ltd. and Supreme Pharmatech Co. Ltd., 399/90-95 Moo 13 Kingkaew Rd. Soi 25/1, T. Rachateva, A. Bangplee, Samutprakan 10540, Thailand.

The current health crisis caused by coronavirus 2019 (COVID-19) and associated pathogens emphasize the urgent need for vaccine systems that can generate protective and long-lasting immune responses. Vaccination, employing peptides, nucleic acids, and other molecules, or using pathogen-based strategies, in fact, is one of the most potent approaches in the management of viral diseases. However, the vaccine candidate requires protection from degradation and precise delivery to the target cells. Read More

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Variation in Peritoneal Dialysis-Related Peritonitis Outcomes in the Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS).

Am J Kidney Dis 2021 May 27. Epub 2021 May 27.

Division of Nephrology, St. Michael's Hospital and the Keenan Research Center in the Li Ka Shing Knowledge Institute, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada. Electronic address:

Rationale & Objective: Peritoneal dialysis (PD)-associated peritonitis is a significant PD-related complication. We describe the likelihood of cure following a peritonitis episode, exploring its association with various patient, peritonitis, and treatment characteristics.

Study Design: Observational prospective cohort study. Read More

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Genetic characterization of an H5N6 avian influenza virus with multiple origins from a chicken in southern China, October 2019.

BMC Vet Res 2021 May 28;17(1):200. Epub 2021 May 28.

College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, 330045, Jiangxi, China.

Background: Highly pathogenic avian influenza viruses (HPAIVs) of H5 subtype pose a great threat to the poultry industry and human health. In recent years, H5N6 subtype has rapidly replaced H5N1 as the most predominate HPAIV subtype circulating in domestic poultry in China. In this study, we describe the genetic and phylogenetic characteristics of a prevalent H5N6 strain in Guangdong, China. Read More

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Not all that glitters is cancer: Not all enlarged lateral pelvic mass is a metastasis.

ANZ J Surg 2021 May 28. Epub 2021 May 28.

Department of Colorectal Surgery, Korea University Anam Hospital, Seoul, South Korea.

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