262 results match your criteria Australasian Physical & Engineering Sciences In Medicine[Journal]


The Prevalence, Impact, and Risk Factors for Persistent Pain After Breast Cancer Surgery in a New Zealand Population.

Pain Med 2019 Mar 19. Epub 2019 Mar 19.

Department of Anaesthesiology, Faculty of Medicine and Health Science, University of Auckland, Auckland, New Zealand.

Objective: Few Australasian studies have assessed persistent pain after breast cancer surgery. This study aims to evaluate the prevalence, impact, and risk factors of moderate to severe persistent pain after breast cancer surgery in a New Zealand population.

Methods: Retrospective cross-sectional study of patients who underwent breast cancer surgery between six and 48 months previously. Read More

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http://dx.doi.org/10.1093/pm/pnz049DOI Listing

Filling the gaps: descriptions of unnamed species included in the latest molecular phylogeny of Pholcidae (Araneae).

Zootaxa 2019 Jan 22;4546(1):1-96. Epub 2019 Jan 22.

Alexander Koenig Research Museum of Zoology, Adenauerallee 160, 53113 Bonn, Germany..

This paper provides formal descriptions of some of the unnamed taxa that were included in the most recent molecular phylogeny of pholcid spiders (Eberle et al. 2018, BMC Evolutionary Biology, 18, 141). The focus is on new genera and on species that belong to recently revised genera. Read More

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http://dx.doi.org/10.11646/zootaxa.4546.1.1DOI Listing
January 2019

ASID/ACIPC position statement - Infection control for patients with Clostridium difficile infection in healthcare facilities.

Infect Dis Health 2019 Feb 17;24(1):32-43. Epub 2018 Nov 17.

Health Pathology, NSW, Australia; Hunter New England Health, NSW, Australia; School of Medicine, University of Newcastle, Newcastle, NSW, Australia.

Background: In 2011, the Australasian Society for Infectious Diseases (ASID) and the Australian Infection Control Association (AICA), now known as the Australasian College of Infection Prevention and Control (ACIPC), produced a position statement on infection control requirements for preventing and controlling Clostridium difficile infection (CDI) in healthcare settings.

Methods: The statement updated in 2017 to reflect new literature available .The authors reviewed the 2011 position statement and critically appraised new literature published between 2011 and 2017 and relevant current infection control guidelines to identify where new evidence had become available or best practice had changed. Read More

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http://dx.doi.org/10.1016/j.idh.2018.10.001DOI Listing
February 2019
4 Reads

Identifying patient-important outcomes in polycystic kidney disease: an international nominal group technique study.

Nephrology (Carlton) 2019 Jan 20. Epub 2019 Jan 20.

Sydney School of Public Health, The University of Sydney, Sydney, Australia.

Aim: Patients with autosomal dominant polycystic kidney disease (ADPKD) are at increased risk of premature mortality, morbidities and complications, which severely impair quality of life. However, patient-centred outcomes are not consistently reported in trials in ADPKD, which can limit shared decision-making. We aimed to identify outcomes important to patients and caregivers and the reasons for their priorities. Read More

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http://doi.wiley.com/10.1111/nep.13566
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http://dx.doi.org/10.1111/nep.13566DOI Listing
January 2019
19 Reads

Dietary assessment toolkits: an overview.

Public Health Nutr 2019 Mar 15;22(3):404-418. Epub 2018 Nov 15.

7Danone Nutricia Research, R.D. 128 Avenue de la Vauve, 91767 Palaiseau Cedex,France.

Objective: A wide variety of methods are available to assess dietary intake, each one with different strengths and weaknesses. Researchers face multiple challenges when diet and nutrition need to be accurately assessed, particularly in the selection of the most appropriate dietary assessment method for their study. The goal of the current collaborative work is to present a collection of available resources for dietary assessment implementation. Read More

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http://dx.doi.org/10.1017/S1368980018002951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368251PMC
March 2019
17 Reads

Vegetables and legumes in new Australasian food launches: how are they being used and are they a healthy choice?

Nutr J 2018 11 9;17(1):104. Epub 2018 Nov 9.

Institute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, 3220, Australia.

Background: Despite the health benefits of regular vegetable and legume consumption, on average Australians are consuming only half of the recommended daily intake. The reasons for this low consumption are complex, and are particularly driven by societal shifts towards convenient and ready-to-eat meal options. It is currently unknown how legumes and vegetables are being utilised in food products within the Australian context, and the nutritional value or level of processing of these products. Read More

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https://nutritionj.biomedcentral.com/articles/10.1186/s12937
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http://dx.doi.org/10.1186/s12937-018-0414-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230301PMC
November 2018
12 Reads

Women and men in the Australasian College of Physical Scientists and Engineers in Medicine: workforce survey.

Australas Phys Eng Sci Med 2019 Mar 2;42(1):33-41. Epub 2018 Nov 2.

Chris O'Brien Lifehouse, Camperdown, NSW, Australia.

A survey was designed to determine aspirations, motivations and workplace experiences of both female and male members of the Australasian College of Physical Scientists and Engineers in Medicine (ACPSEM). The survey collected both quantitate and qualitative data, including open ended questions. This paper reports the survey's qualitative results. Read More

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http://link.springer.com/10.1007/s13246-018-0706-z
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http://dx.doi.org/10.1007/s13246-018-0706-zDOI Listing
March 2019
10 Reads

Widespread emergency department access block: a human rights issue in Australia?

Australas Psychiatry 2019 Feb 31;27(1):10-13. Epub 2018 Oct 31.

Professor of Psychiatry, the University of Melbourne, Melbourne, VIC, and; Chair of Psychiatry, St Vincent's Health, Melbourne, VIC, Australia.

Objective:: There are increasing demands on emergency psychiatrists with higher numbers of mental health presentations, and longer stays in emergency departments (EDs). Australia, like other English speaking countries, funds considerably lower numbers of psychiatric beds than average for Organisation for Economic Co-operation and Development (OECD) countries. Consequently, acute bed occupancy is high, and a bed is frequently unavailable when a person needs admission. Read More

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http://dx.doi.org/10.1177/1039856218810156DOI Listing
February 2019
3 Reads
0.560 Impact Factor

Australasian recommendations for quality assurance in kilovoltage radiation therapy from the Kilovoltage Dosimetry Working Group of the Australasian College of Physical Scientists and Engineers in Medicine.

Australas Phys Eng Sci Med 2018 Dec;41(4):781-808

Genesis Cancer Care Queensland, Level 8 Premion Place, 39 White Street, Southport, QLD, 4125, Australia.

The Australasian College of Physical Scientists and Engineers in Medicine (ACPSEM) Radiation Oncology Specialty Group (ROSG) formed a series of working groups to develop recommendations for guidance of radiation oncology medical physics practice within the Australasian setting. These recommendations provide a standard for safe work practices and quality control. It is the responsibility of the medical physicist to ensure that locally available equipment and procedures are sufficiently sensitive to establish compliance. Read More

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http://link.springer.com/10.1007/s13246-018-0692-1
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http://dx.doi.org/10.1007/s13246-018-0692-1DOI Listing
December 2018
27 Reads

Engineering Anisotropic Muscle Tissue using Acoustic Cell Patterning.

Adv Mater 2018 Oct 12;30(43):e1802649. Epub 2018 Sep 12.

Department of Materials, Department of Bioengineering, and Institute for Biomedical Engineering, Imperial College London, London, SW7 2AZ, UK.

Tissue engineering has offered unique opportunities for disease modeling and regenerative medicine; however, the success of these strategies is dependent on faithful reproduction of native cellular organization. Here, it is reported that ultrasound standing waves can be used to organize myoblast populations in material systems for the engineering of aligned muscle tissue constructs. Patterned muscle engineered using type I collagen hydrogels exhibits significant anisotropy in tensile strength, and under mechanical constraint, produced microscale alignment on a cell and fiber level. Read More

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http://doi.wiley.com/10.1002/adma.201802649
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http://dx.doi.org/10.1002/adma.201802649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386124PMC
October 2018
23 Reads

HDL subfraction changes with a low-fat, plant-based Complete Health Improvement Program (CHIP).

Asia Pac J Clin Nutr 2018;27(5):1002-1009

Lifestyle Research Centre, Cooranbong, NSW, Australia.

Background And Objectives: Low HDL concentrations are considered an important risk factor for cardiovascular disease. Interventions promoting a low-fat, plant-based eating pattern appear to reduce CVD risk while paradoxically also reducing HDL concentrations. Recent studies show HDL to comprise a range of subfractions, but the role these play in ameliorating the risk of CVD is unclear. Read More

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http://www.airitilibrary.com/Publication/alDetailedMesh?DocI
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http://dx.doi.org/10.6133/apjcn.052018.05DOI Listing
January 2018
10 Reads

Evaluating the impact of 2006 Australasian Clinical Practice Guidelines for nutrition in children with cystic fibrosis in Australia.

Respir Med 2018 09 19;142:7-14. Epub 2018 Jul 19.

Monash Medical Centre, Monash Health, Melbourne, Victoria, Australia.

Objectives: To determine the association between the implementation of the 2006 Australasian Clinical Practice Guidelines for Nutrition in Cystic Fibrosis (CF) and the nutritional status of children participating in the Australian Cystic Fibrosis Data Registry (ACFDR).

Methods: This research consisted of a quantitative study using ACFDR data and a survey of clinicians and dietitians treating children with CF. Two independent cohorts of children (2-5 years and 6-11 years) were selected from ACFDR between 1998 and 2014 (N = 2304). Read More

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http://dx.doi.org/10.1016/j.rmed.2018.07.007DOI Listing
September 2018
6 Reads

Prevalence and pathogenesis of osteopenia and osteoporosis in epidermolysis bullosa: An evidence-based review.

Exp Dermatol 2018 Aug 17. Epub 2018 Aug 17.

Department of Dermatology, St George Hospital, Sydney, NSW, Australia.

Background: Osteopenia or osteoporosis is one of the many comorbidities in patients with Epidermolysis Bullosa (EB). Current literature on the prevalence of osteoporosis in EB is scarce.

Objective: This review will analyse the current literature in the field of patients with compromised bone health in EB and any articles on the prevalence of such diseases in EB groups. Read More

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http://dx.doi.org/10.1111/exd.13771DOI Listing
August 2018
1 Read

Medical physics workforce modelling: do we need what we want?

Authors:
Claire Dempsey

Australas Phys Eng Sci Med 2018 Sep;41(3):565-566

Calvary Mater Newcastle Hospital, Waratah, NSW, Australia.

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http://link.springer.com/10.1007/s13246-018-0663-6
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http://dx.doi.org/10.1007/s13246-018-0663-6DOI Listing
September 2018
2 Reads

Future forum, Hobart, October 29, 2017: examining the role of medical physics in cancer research.

Australas Phys Eng Sci Med 2018 Sep 25;41(3):571-579. Epub 2018 Jun 25.

Centre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW, Australia.

This commentary reports on a forum held in October 2017 in Hobart, Tasmania, attended by 20 Australasian medical physicists, to consider the future role of medical physics, as well as non-medical physics and allied disciplines, in oncology research. Attendees identified important areas of oncology research which physicists can be contributing to, with these evaluated in the context of a set of "Provocative Questions" recently generated by the American Association of Physicists in Medicine. Primary perceived barriers to participation in research were identified, including a "lack of knowledge of cancer science", together with potential solutions. Read More

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http://dx.doi.org/10.1007/s13246-018-0659-2DOI Listing
September 2018
2 Reads

A randomized comparison of three prandial insulin dosing algorithms for children and adolescents with Type 1 diabetes.

Diabet Med 2018 10 19;35(10):1440-1447. Epub 2018 Jun 19.

Hunter Medical Research Institute, Newcastle, NSW, Australia.

Aim: To compare systematically the impact of two novel insulin-dosing algorithms (the Pankowska Equation and the Food Insulin Index) with carbohydrate counting on postprandial glucose excursions following a high fat and a high protein meal.

Methods: A randomized, crossover trial at two Paediatric Diabetes centres was conducted. On each day, participants consumed a high protein or high fat meal with similar carbohydrate amounts. Read More

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http://dx.doi.org/10.1111/dme.13703DOI Listing
October 2018
21 Reads

The Relationship Between Body Mass Index and Organism-Specific Peritonitis.

Perit Dial Int 2018 May-Jun;38(3):206-214

Hôpital Maisonneuve-Rosemont, Université de Montréal, Montreal, Canada

Background: Obesity is increasingly prevalent worldwide, and a greater number of patients initiate renal replacement therapy with a high body mass index (BMI). This study aimed to evaluate the association between BMI and organism-specific peritonitis.

Methods: All adult patients who initiated peritoneal dialysis (PD) in Australia between January 2004 and December 2013 were included. Read More

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http://dx.doi.org/10.3747/pdi.2017.00188DOI Listing
December 2018
20 Reads

Parental feeding practices associated with children's eating and weight: What are parents of toddlers and preschool children doing?

Appetite 2018 Sep 26;128:120-128. Epub 2018 May 26.

Institute for Physical Activity and Nutrition, School of Exercise and Nutrition Sciences, Deakin University, Geelong, Australia.

Parental feeding practices are associated with children's eating behaviours and weight, yet current use of such practices lacks detailed description. This limits our understanding of which behaviours to target to promote healthy growth. We explored the frequency with which a range of parental feeding practices occurs in mothers of toddler and preschool children. Read More

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http://dx.doi.org/10.1016/j.appet.2018.05.145DOI Listing
September 2018

Impact of Particle Size and Polydispersity Index on the Clinical Applications of Lipidic Nanocarrier Systems.

Pharmaceutics 2018 May 18;10(2). Epub 2018 May 18.

Australasian Nanoscience and Nanotechnology Initiative, 8054 Monash University LPO, Clayton, Victoria 3168, Australia.

Lipid-based drug delivery systems, or lipidic carriers, are being extensively employed to enhance the bioavailability of poorly-soluble drugs. They have the ability to incorporate both lipophilic and hydrophilic molecules and protecting them against degradation in vitro and in vivo. There is a number of physical attributes of lipid-based nanocarriers that determine their safety, stability, efficacy, as well as their in vitro and in vivo behaviour. Read More

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http://www.mdpi.com/1999-4923/10/2/57
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http://dx.doi.org/10.3390/pharmaceutics10020057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027495PMC
May 2018
3 Reads

Implementing best practice into the emergency department triage process.

Int J Evid Based Healthc 2019 Mar;17(1):27-35

Evidence in Practice Unit, Mater Misericordiae Limited and Queensland Centre for Evidence-Based Nursing and Midwifery: A Joanna Briggs Institute Centre of Excellence, Brisbane, Queensland, Australia.

Background: Triage is the process by which emergency departments (EDs) sort patients presenting for medical treatment. The Australasian Triage Scale, validated to measure urgency, answers the question 'This patient should wait for medical assessment and treatment no longer than…' Multiple patients may present within short time frames, and some will have conditions that have outcomes directly related to timeliness of treatment such as stroke, sepsis and myocardial infarction. The safety of patients within the ED is thus directly related to the triage system. Read More

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http://dx.doi.org/10.1097/XEB.0000000000000144DOI Listing
March 2019
43 Reads

Morphometry of the nulliparous pelvic floor.

Ultrasound Obstet Gynecol 2018 Nov;52(5):672-676

School of Women's and Children's Health, University of New South Wales, Sydney, NSW, Australia.

Objectives: To describe morphometry of the pelvic floor in a large population of nulliparous women, comparing those with and those without pelvic pain. We also aimed to assess its association with characteristics such as age and body mass index (BMI).

Methods: This was a prospective study performed between January 2013 and November 2015 in non-pregnant nulliparous women attending a general gynecology clinic. Read More

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http://dx.doi.org/10.1002/uog.19075DOI Listing
November 2018
4 Reads

Long-term outcome of selective neurectomy for refractory periocular synkinesis.

Laryngoscope 2018 10 18;128(10):2291-2295. Epub 2018 Apr 18.

Department of Otolaryngology/Head and Neck Surgery, Massachusetts Eye and Ear Infirmary and Harvard Medical School, Boston, Massachusetts, U.S.A.

Objective: The objective of this study was to investigate the long-term effect and treatment stability of selective neurectomy for refractory periocular synkinesis.

Methods: We performed a retrospective review of all patients treated with highly selective neurectomy for refractory periocular synkinesis between August 2009 and August 2015. Primary outcome was time to recommencing treatment for periocular synkinesis. Read More

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http://doi.wiley.com/10.1002/lary.27225
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http://dx.doi.org/10.1002/lary.27225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221084PMC
October 2018
6 Reads

Molecular phylogenetics and species limits in a cryptically coloured radiation of Australo-Papuan passerine birds (Pachycephalidae: Colluricincla).

Mol Phylogenet Evol 2018 07 8;124:100-105. Epub 2018 Mar 8.

Center for Macroecology, Evolution and Climate, Natural History Museum of Denmark, University of Copenhagen, Universitetsparken 15, DK-2100 Copenhagen, Denmark.

Detailed knowledge of species limits is an essential component of the study of biodiversity. Although accurate species delimitation usually requires detailed knowledge of both genetic and phenotypic variation, such variation may be limited or unavailable for some groups. In this study, we reconstruct a molecular phylogeny for all currently recognized species and subspecies of Australasian shrikethrushes (Colluricincla), including the first sequences of the poorly known C. Read More

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http://dx.doi.org/10.1016/j.ympev.2018.02.029DOI Listing
July 2018
4 Reads

Surgical versus non-surgical management of type B ankle fractures with minimal talar shift in adults: a systematic review.

ANZ J Surg 2018 Nov 8;88(11):1123-1128. Epub 2018 Mar 8.

Whitlam Orthopaedic Research Centre, Ingham Institute for Applied Medical Research, South Western Sydney Clinical School, The University of New South Wales, Sydney, New South Wales, Australia.

Background: This systematic review aims to determine the effectiveness of surgical and non-surgical management for the type B ankle fracture with minimal talar shift.

Methods: Two authors independently systematically searched the following databases: MEDLINE, EMBASE and CENTRAL. Only randomized controlled trials were included that evaluated surgical versus non-surgical management of type B ankle fracture with minimal talar shift in adults. Read More

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http://dx.doi.org/10.1111/ans.14445DOI Listing
November 2018
6 Reads

Morbid obesity impairs adequacy of thoracic compressions in a simulation-based model.

Anaesth Intensive Care 2018 03;46(2):171-177

Emergency and Retrieval Medicine Consultant, Alice Springs Hospital; Honorary Academic Fellow, Baker Research Institute; Alice Springs, Northern Territory.

Adequate cardiopulmonary resuscitation is an important predictor of survival, however, obesity provides a significant physical barrier to thoracic compressions. This study explores the effect of morbid obesity on compression adequacy. We performed a prospective randomised controlled crossover study, assessing the adequacy of thoracic compressions on a manikin modified to emulate a morbidly obese patient. Read More

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http://dx.doi.org/10.1177/0310057X1804600205DOI Listing

Randomised controlled trial to determine the efficacy and safety of prescribed water intake to prevent kidney failure due to autosomal dominant polycystic kidney disease (PREVENT-ADPKD).

BMJ Open 2018 01 21;8(1):e018794. Epub 2018 Jan 21.

Centre for Transplant and Renal Research, The Westmead Institute for Medical Research, The University of Sydney, Sydney, Australia.

Introduction: Maintaining fluid intake sufficient to reduce arginine vasopressin (AVP) secretion has been hypothesised to slow kidney cyst growth in autosomal dominant polycystic kidney disease (ADPKD). However, evidence to support this as a clinical practice recommendation is of poor quality. The aim of the present study is to determine the long-term efficacy and safety of prescribed water intake to prevent the progression of height-adjusted total kidney volume (ht-TKV) in patients with chronic kidney disease (stages 1-3) due to ADPKD. Read More

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http://dx.doi.org/10.1136/bmjopen-2017-018794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780847PMC
January 2018
24 Reads
1 Citation
2.060 Impact Factor

Deaths in Incorrectly Identified Low-Surgical-Risk Patients.

World J Surg 2018 07;42(7):1997-2000

Department of Hepatobiliary and Upper Gastrointestinal Surgery, The Queen Elizabeth Hospital, Adelaide, SA, Australia.

Background: The American Society of Anesthesiologists (ASA) physical classification system was developed for assessing anaesthetic risk, but is often also used to estimate surgical death risk. Patients with low ASA grades (ASA 1 or 2) are expected to have better surgical outcomes than patients with higher ASA grades (ASA ≥ 4). This study examined the course to death in patients classified as ASA 1 or 2 was examined, to investigate possible factors in unexpected deaths, in addition to evaluating the use of ASA grades by clinicians. Read More

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http://dx.doi.org/10.1007/s00268-017-4427-3DOI Listing
July 2018
1 Read

Revision of the Agrilus humilis species-group (Coleoptera: Buprestidae: Agrilini) with description of thirteen new species from Southeastern Asia.

Authors:
Eduard Jendek

Zootaxa 2017 Dec 10;4363(2):249-271. Epub 2017 Dec 10.

Department of Forest Protection and Entomology, Faculty of Forestry and Wood Sciences, Czech University of Life Sciences, Kamýcká 1176, CZ-165 21, Prague 6-Suchdol, Czech Republic..

The newly defined Agrilus humilis species-group comprising twenty taxa of Indo-Malayan and Australasian region is revised based on the examination of type specimens. The taxonomic concept and distribution of all known species is critically revised for the first time since they were described. The complete commented bibliographic data are given for each name. Read More

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http://dx.doi.org/10.11646/zootaxa.4363.2.5DOI Listing
December 2017
2 Reads

Medical physics publishing in a changing research environment: the Australasian Physical & Engineering Sciences in Medicine 40th anniversary editorial.

Australas Phys Eng Sci Med 2017 Dec;40(4):771-776

Cancer Care Services, Royal Brisbane & Women's Hospital, Brisbane, Australia.

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http://dx.doi.org/10.1007/s13246-017-0602-yDOI Listing
December 2017

Ultraconserved elements (UCEs) resolve the phylogeny of Australasian smurf-weevils.

PLoS One 2017 22;12(11):e0188044. Epub 2017 Nov 22.

State Museum of Natural History Karlsruhe, Karlsruhe, Germany.

Weevils (Curculionoidea) comprise one of the most diverse groups of organisms on earth. There is hardly a vascular plant or plant part without its own species of weevil feeding on it and weevil species diversity is greater than the number of fishes, birds, reptiles, amphibians and mammals combined. Here, we employ ultraconserved elements (UCEs) designed for beetles and a novel partitioning strategy of loci to help resolve phylogenetic relationships within the radiation of Australasian smurf-weevils (Eupholini). Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0188044PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699822PMC
December 2017
2 Reads

Surgical management of extensive hypertrophic scarring of the halluces secondary to a decade of untreated onychocryptosis: An illustrative case report.

SAGE Open Med Case Rep 2017 6;5:2050313X17740514. Epub 2017 Nov 6.

Australasian College of Podiatric Surgeons, Melbourne, VIC, Australia.

Extensive hypertrophic scarring of the halluces secondary to chronic onychocryptosis is a rare condition, which causes significant physical and psychosocial effects. In this case, a 31-year-old male developed large lesions on both great toes after he delayed treatment of chronic hallucal onychocryptosis for over a decade. Current treatment options for hypertrophic and keloid lesions in the foot and ankle vary considerably and differentiation is critical for appropriate treatment planning. Read More

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http://dx.doi.org/10.1177/2050313X17740514DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680933PMC
November 2017
2 Reads

"I have lost in every facet of my life": the hidden burden of severe asthma.

Eur Respir J 2017 09 20;50(3). Epub 2017 Sep 20.

Clinical Management Group, Woolcock Institute of Medical Research, University of Sydney, Sydney, Australia.

People with severe asthma are thought to face a sizeable daily disease burden. This study aimed to explore the little-known life experiences of people living with severe asthma.Adults with severe asthma were invited for telephone interview. Read More

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http://dx.doi.org/10.1183/13993003.00765-2017DOI Listing
September 2017
26 Reads

Health-related quality of life associated with regorafenib treatment in refractory advanced gastric adenocarcinoma.

Gastric Cancer 2018 May 16;21(3):473-480. Epub 2017 Aug 16.

Australasian Gastro-Intestinal Trials Group, Camperdown, Australia.

Background: The INTEGRATE phase II multinational randomized controlled trial demonstrated the activity of regorafenib on progression-free survival (PFS) in patients with refractory advanced gastric adenocarcinoma. We sought to evaluate whether these PFS gains had the potential to be offset by quality of life (QoL) impacts from treatment side effects and to thereby determine the appropriateness of continuing development to phase III.

Methods: QoL was assessed in INTEGRATE at baseline and at each 4 weeks thereafter, until discontinuation of study treatment, using the QLQ-C30, STO22, and EQ-5D questionnaires. Read More

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http://dx.doi.org/10.1007/s10120-017-0754-1DOI Listing
May 2018
41 Reads

Visceral fat mass: is it the link between uric acid and diabetes risk?

Lipids Health Dis 2017 Jul 24;16(1):142. Epub 2017 Jul 24.

School of Medical Sciences, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.

Background: Uric acid (UA) has been suggested as a novel risk factor for diabetes. However, its definite role in this prevalent disease is still the subject of much discussion because it is always accompanied with other major risk factors such as obesity and high visceral adiposity. In order to clarify the role of UA in diabetes, this study aimed to investigate the associations between plasma UA and fasting plasma glucose, HbA1c, lipid profile and inflammatory markers after accounting for the contribution of other diabetes risk factors such as BMI and VAT fat mass. Read More

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http://dx.doi.org/10.1186/s12944-017-0532-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525310PMC
July 2017
3 Reads

Poor Employment Conditions Adversely Affect Mental Health Outcomes Among Surgical Trainees.

J Surg Educ 2018 Jan - Feb;75(1):156-163. Epub 2017 Jul 17.

Department of Surgery, Angliss Hospital, Eastern Health, Melbourne, Victoria, Australia.

Background: Poor mental health in junior clinicians is prevalent and may lead to poor productivity and significant medical errors. We aimed to provide contemporary data on the mental health of surgical trainees and identify risk factors relating to poorer mental health outcomes.

Methods: A detailed questionnaire was developed comprising questions based on the 36-item short-form health survey (SF-36) and Physical Activity Questionnaire. Read More

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http://dx.doi.org/10.1016/j.jsurg.2017.06.030DOI Listing
November 2018
6 Reads

Rhigonema naylae n. sp. (Rhigonematomorpha: Rhigonematidae) a new parasitic nematode from a Japanese polydesmid millipede (Polydesmida: Xystodesmidae).

Zootaxa 2017 05 22;4269(2):277-286. Epub 2017 May 22.

Instituto de Ecología y Sistemática, Carretera Varona 11835 e/ Oriente y Lindero, La Habana 19, CP 11900, Calabazar, Boyeros, La Habana, Cuba.

Rhigonema naylae n. sp. (Rhigonematomorpha: Rhigonematidae) is described from the hindgut of the polydesmid millipede Parafontaria laminata (Attems, 1909) (Polydesmida: Xystodesmidae), from Aichi prefecture, Japan. Read More

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http://dx.doi.org/10.11646/zootaxa.4269.2.6DOI Listing
May 2017
2 Reads

Eating psychopathology and psychosocial impairment in patients treated at a Singapore eating disorders treatment programme.

Singapore Med J 2018 01 15;59(1):33-38. Epub 2017 May 15.

Department of Psychiatry, Singapore General Hospital, Singapore.

Introduction: There is limited data on the psychopathology of eating disorders in Singapore. This study: (a) described levels of eating psychopathology and psychosocial impairment among individuals diagnosed with eating disorders at our hospital; and (b) compared the related psychopathology of these patients.

Methods: Between 1 August 2010 and 31 July 2012, 257 individuals who met the diagnostic criteria for eating disorders completed the Eating Disorder Examination Questionnaire (EDE-Q) and Clinical Impairment Assessment questionnaire (CIA). Read More

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http://dx.doi.org/10.11622/smedj.2017042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778256PMC
January 2018
34 Reads

Dentists' restorative decision-making and implications for an 'amalgamless' profession. Part 4: clinical factor.

Aust Dent J 2017 Sep 28;62(3):363-371. Epub 2017 Jun 28.

Melbourne Dental School, University of Melbourne, Melbourne, Victoria, Australia.

Background: The Minamata Convention embodies a worldwide reduction in the production and use of mercury and mercury-containing products and processes, including a phase-down of dental amalgam. This will change the approach to the use of direct restorative materials in the near future. There is little research as to the influence of clinical factors on dentists' decision-making which may be of use when determining the impact of any change. Read More

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http://dx.doi.org/10.1111/adj.12519DOI Listing
September 2017
2 Reads

Comparison of adverse pregnancy outcomes based on the new IADPSG 2010 gestational diabetes criteria and maternal body mass index.

Aust N Z J Obstet Gynaecol 2017 Oct 19;57(5):533-539. Epub 2017 Apr 19.

Department of Obstetrics and Gynaecology, Nepean Hospital, Sydney, New South Wales, Australia.

Background: The diagnostic criteria for gestational diabetes (GDM) have been controversial following the International Association for Pregnancy Study Groups (IADPSG) 2010 recommendations to lower the diagnostic fasting blood sugar level threshold.

Aim: To assess the pregnancy-related outcomes of women according to the different diagnostic criteria for GDM adjusting for body mass index categories.

Method: A retrospective observational cohort study was conducted on 4081 pregnant women with positive 50 g glucose challenge test but without pre-gestational diabetes. Read More

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http://dx.doi.org/10.1111/ajo.12628DOI Listing
October 2017
4 Reads

The Anorexia Nervosa Genetics Initiative: Study description and sample characteristics of the Australian and New Zealand arm.

Aust N Z J Psychiatry 2017 Jun 5;51(6):583-594. Epub 2017 Apr 5.

1 Genetic Epidemiology Laboratory, QIMR Berghofer Institute of Medical Research, Brisbane, QLD, Australia.

Objectives: Anorexia nervosa is a severe psychiatric disorder with high mortality rates. While its aetiology is poorly understood, there is evidence of a significant genetic component. The Anorexia Nervosa Genetics Initiative is an international collaboration which aims to understand the genetic basis of the disorder. Read More

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http://dx.doi.org/10.1177/0004867417700731DOI Listing
June 2017
28 Reads

Economic evaluation of an exercise-counselling intervention to enhance smoking cessation outcomes: The Fit2Quit trial.

Tob Induc Dis 2017 29;15:21. Epub 2017 Mar 29.

University of Auckland, Private Bag 92019, Auckland, New Zealand.

Background: In the Fit2Quit randomised controlled trial, insufficiently-active adult cigarette smokers who contacted Quitline for support to quit smoking were randomised to usual Quitline support or to also receive ≤10 face-to-face and telephone exercise-support sessions delivered by trained exercise facilitators over the 24-week trial. This paper aims to determine the cost-effectiveness of an exercise-counselling intervention added to Quitline compared to Quitline alone in the Fit2Quit trial.

Methods: Within-trial and lifetime cost-effectiveness were assessed. Read More

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http://dx.doi.org/10.1186/s12971-017-0126-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371274PMC
March 2017
30 Reads

The SIESTA Trial: A Randomized Study Investigating the Efficacy, Safety, and Tolerability of Acupressure versus Sham Therapy for Improving Sleep Quality in Patients with End-Stage Kidney Disease on Hemodialysis.

Evid Based Complement Alternat Med 2017 21;2017:7570352. Epub 2017 Feb 21.

Department of Nephrology, Princess Alexandra Hospital, Brisbane, QLD, Australia; Australasian Kidney Trials Network, The University of Queensland, Brisbane, QLD, Australia; Centre for Kidney Disease Research, School of Medicine, The University of Queensland, Translational Research Institute, Woolloongabba, Brisbane, QLD, Australia.

. To compare the effectiveness of real acupressure versus sham acupressure therapy in improving sleep quality in patients receiving hemodialysis (HD) or hemodiafiltration (HDF). . Read More

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http://dx.doi.org/10.1155/2017/7570352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339536PMC
February 2017
35 Reads

Vitamin D, bones and muscle: myth versus reality.

Australas J Ageing 2017 Mar;36 Suppl 1:8-13

Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts, USA.

Objectives: Evidence regarding the efficacy and dosing of vitamin D on fall and fracture prevention, with or without calcium, is characterised by uncertainty.

Methods: A panel of experts was organised at the First Australasian Conference on Sarcopenia and Frailty in Melbourne, Australia, in November 2016 to provide an interpretation of the current evidence and to give their opinions regarding the supplementation of vitamin D in three hypothetical cases.

Results And Conclusion: The authors conclude that (i) target serum 25(OH)D concentration should be 50 to 60 nmol/L year round, with a conservative upper limit <100 nmol/L; (ii) change in serum concentrations at any given dose is highly variable among individuals; (iii) dosing interval may need to be <2 months to have a continuous benefit; (iv) a loading dose can raise levels to target quickly, but there is no evidence yet that this has any positive effect on falls or fracture outcomes; and (v) a maintenance dose of 1000 IU/day, or given as an equivalent dose weekly or monthly, is sufficient for most individuals. Read More

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http://dx.doi.org/10.1111/ajag.12408DOI Listing
March 2017
4 Reads

The prevalence of diabetes after gestational diabetes - An Australian perspective.

Aust N Z J Obstet Gynaecol 2017 Apr 8;57(2):157-161. Epub 2017 Mar 8.

Department of Research, Research Office, Wollongong, New South Wales, Australia.

Background: Women with gestational diabetes mellitus (GDM) are likely to develop diabetes in later life. International reports and reviews indicate a variable but generally high rate of conversion. However, data from international reports are difficult to apply to an Australian population. Read More

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http://dx.doi.org/10.1111/ajo.12581DOI Listing

Consensus statement for the treatment of infantile haemangiomas with propranolol.

Australas J Dermatol 2017 May 1;58(2):155-159. Epub 2017 Mar 1.

Royal Children's Hospital, Melbourne, Victoria, Australia.

Although most infantile haemangiomas do not require treatment due to a natural history of spontaneous involution, some require early intervention. The Australasian Vascular Anomalies Network and the Australasian Paediatric Dermatology Network have developed a consensus statement for the treatment of infantile haemangiomas with oral propranolol. Infants with haemangiomas that are life threatening, at risk of ulceration, or at risk of causing a significant functional impairment, psychological impact or physical deformity should be treated early with oral propranolol. Read More

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http://dx.doi.org/10.1111/ajd.12600DOI Listing
May 2017
20 Reads

Response of Leptospermum scoparium, Kunzea robusta and Pinus radiata to contrasting biowastes.

Sci Total Environ 2017 Jun 24;587-588:258-265. Epub 2017 Feb 24.

Lincoln University, Faculty of Agriculture and Life Sciences, Department of Soil and Physical Sciences, P O Box 84, Lincoln 7647, New Zealand.

The myrtaceae family has a cosmopolitan distribution and includes the Australasian native species Leptospermum scoparium (mānuka) and Kunzea robusta (kānuka), which are of economic interest for the production of high-value honey and essential oils. Potentially, these species could be established on low-fertility or degraded soils that have been amended with biowastes, including biosolids and sawdust. We aimed to determine the effect of these biowastes on nitrate leaching and the growth and chemical composition of these plant species compared to Pinus radiata (pine), a common forestry species. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2017.02.134DOI Listing
June 2017
3 Reads

Physical Activity Promotion, Beliefs, and Barriers Among Australasian Oncology Nurses.

Oncol Nurs Forum 2017 03;44(2):235-245

University of Sydney.

Purpose/objectives: To describe the physical activity (PA) promotion practices, beliefs, and barriers of Australasian oncology nurses and gain preliminary insight into how PA promotion practices may be affected by the demographics of the nurses.
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Design: Cross-sectional survey. Read More

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http://dx.doi.org/10.1188/17.ONF.235-245DOI Listing
March 2017
6 Reads

The Australasian Diabetes Data Network: first national audit of children and adolescents with type 1 diabetes.

Med J Aust 2017 Feb;206(3):121-125

University of Sydney, Sydney, NSW.

Objectives: To assess glycaemic control, anthropometry and insulin regimens in a national sample of Australian children and adolescents with type 1 diabetes.

Design: Cross-sectional analysis of de-identified, prospectively collected data from the Australasian Diabetes Data Network (ADDN) registry.

Setting: Five paediatric diabetes centres in New South Wales, Queensland, South Australia, Victoria and Western Australia. Read More

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February 2017
40 Reads

Habitat structure is linked to the evolution of plumage colour in female, but not male, fairy-wrens.

BMC Evol Biol 2017 01 26;17(1):35. Epub 2017 Jan 26.

Division of Ecology and Evolution, Research School of Biology, Australian National University, Canberra, 0200, Australia.

Background: Both natural and sexual selection may drive the evolution of plumage colouration in birds. This can lead to great variation in plumage not only across species, but also between sexes within species. Australasian fairy-wrens are famous for their brightly coloured males, which exhibit colours ranging from bright blue to red and black. Read More

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http://dx.doi.org/10.1186/s12862-016-0861-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270345PMC
January 2017
3 Reads

Body Mass Index-Related Mortality in Patients with Type 2 Diabetes and Heterogeneity in Obesity Paradox Studies: A Dose-Response Meta-Analysis.

PLoS One 2017 3;12(1):e0168247. Epub 2017 Jan 3.

Department of Family Medicine, Korea University College of Medicine, Seoul, South Korea.

Objective: We conducted a systematic review and meta-analysis of studies to quantify the association between body mass index (BMI) and the risks of all-cause and cardiovascular mortality in patients with type 2 diabetes.

Methods: We included studies assessing the impact of BMI on all-cause and cardiovascular mortality in patients with type 2 diabetes. Data were combined using a random-effects dose-response model. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0168247PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207428PMC
August 2017
5 Reads
2 Citations
3.234 Impact Factor