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Australas J Dermatol 2020 Jul 7. Epub 2020 Jul 7.

Department of Dermatology and Venereology, School of Medicine, Hacettepe University, Ankara, Turkey.

Recent reports indicate that hydroxychloroquine is a potential new treatment option for alopecia universalis; thus, we aimed to report on the safety and efficacy of hydroxychloroquine in 6 patients with refractory alopecia universalis that were treated with 400 mg/d continuously for ≥6 months. The treatment outcome was retrospectively evaluated using the Severity of Alopecia Tool (SALT), and at the end of 6 months, patients with a ≥50% decrease in the SALT score were considered as strong responders, a 5%-50% decrease as intermediate responders and a <5% decrease as non-responders. The present findings indicate that hydroxychloroquine is not an effective treatment since in 5 of the 6 patients it was discontinued at the end of 6 months due to lack of hair regrowth, whereas only a 6-year-old boy responded with a SALT score change of 8% after the 12th month. Read More

Australas J Dermatol 2020 Jul 7. Epub 2020 Jul 7.

The Skin Hospital, Sydney, New South Wales, Australia.

Australas J Dermatol 2020 Jul 7. Epub 2020 Jul 7.

National Skin Centre, Singapore, Singapore.

Australas J Dermatol 2020 Jul 6. Epub 2020 Jul 6.

South Australian Institute of Ophthalmology, Royal Adelaide Hospital, The University of Adelaide, Adelaide, Australia.

There has been uncertainty about the demographics and anatomical distribution of cutaneous sebaceous carcinoma. This study aims to investigate these uncertainties by analysing data from various countries. Data were obtained from cancer registries of the United States, England, Norway and Taiwan, and incidence rates were calculated with uniform age-adjustment. Read More

Australas J Dermatol 2020 Jul 6. Epub 2020 Jul 6.

Department of Dermatology, St Vincent's Hospital, Fitzroy, Victoria, Australia.

Australas J Dermatol 2020 Jul 6. Epub 2020 Jul 6.

Department of Dermatology, The Royal Melbourne Hospital, Parkville, Victoria, Australia.

Australas J Dermatol 2020 Jul 6. Epub 2020 Jul 6.

South East Dermatology, Annerley, Queensland, Australia.

Australas J Dermatol 2020 Jul 6. Epub 2020 Jul 6.

Dermatology Department, Hospital Universitario "Dr. José Eleuterio González", Universidad Autónoma de Nuevo León, Monterrey, Mexico.

Australas J Dermatol 2020 Jul 1. Epub 2020 Jul 1.

Dermatology Clinic and Department "G.F. Ingrassia" Section of Anatomic Pathology, University of Catania, Catania, Italy.

Australas J Dermatol 2020 Jul 1. Epub 2020 Jul 1.

Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Australas J Dermatol 2020 Jun 30. Epub 2020 Jun 30.

Department of Dermatology, 306 Hospital of PLA, Beijing, China.

Australas J Dermatol 2020 Jun 29. Epub 2020 Jun 29.

University Clinic of Dermatology , Hospital de Santa Maria, Lisbon, Portugal.

Juvenile gangrenous vasculitis of the scrotum is a rare entity of unknown aetiology which should be considered in the differential diagnosis of genital ulcers, mainly with those caused by sexually transmitted infections. The authors report a case of a 23-year-old patient who presented a single painful scrotal ulcer developing shortly after an episode of pharyngotonsillitis. The ulcer was treated with oral corticosteroids with total healing and no relapse in over two years of follow-up. Read More

Australas J Dermatol 2020 Jun 29. Epub 2020 Jun 29.

Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia.

Eighty consecutive Chinese patients diagnosed with Alzheimer disease were assessed for darkening of grey hair. Of the 62 eligible patients (mean age = 79.3 ± 7. Read More

Australas J Dermatol 2020 Jun 25. Epub 2020 Jun 25.

Concord Repatriation General Hospital, Concord, NSW, Australia.

Eosinophilic cellulitis is a rare inflammatory skin disease of unknown aetiology, first described by George Wells in 1971 as a recurrent granulomatous dermatitis with eosinophilia. It is typically characterised by recurrent pruritic erythematous plaques, vesicles or bullae usually involving the extremities and trunk. Many cases of eosinophilic cellulitis are difficult to treat and traditionally require long course of oral steroids, resulting in steroid side effects. Read More

Australas J Dermatol 2020 Jun 25. Epub 2020 Jun 25.

Department of dermatology, the third people's hospital of Hangzhou, Hangzhou city, China.

Australas J Dermatol 2020 Jun 24. Epub 2020 Jun 24.

Department of Dermatology, Royal North Shore Hospital, St Leonards, Australia.

Australas J Dermatol 2020 Jun 23. Epub 2020 Jun 23.

Department of Dermatology, Hospital Arnau de Vilanova, Valencia, Spain.

Australas J Dermatol 2020 Jun 23. Epub 2020 Jun 23.

Department of Dermatology, Waikato Hospital, Waikato District Health Board, Hamilton, New Zealand.

Background/objectives: Basal cell carcinoma (BCC) is the most commonly occurring skin cancer. BCCs have been found to generally grow slowly. Data are limited on how the dermoscopic characteristics of BCCs evolve. Read More

Australas J Dermatol 2020 Jun 23. Epub 2020 Jun 23.

Department of Dermatology, Monash Health, Clayton, Victoria, Australia.

Australas J Dermatol 2020 Jun 23. Epub 2020 Jun 23.

Dermatology Clinic, Maggiore Hospital of Trieste, University of Trieste, Trieste, Italy.

Australas J Dermatol 2020 Jun 23. Epub 2020 Jun 23.

Sinclair Dermatology, East Melbourne, Victoria, Australia.

Australas J Dermatol 2020 Jun 22. Epub 2020 Jun 22.

Department of Dermatology, National Taiwan University Hospital, Taipei, Taiwan.

Australas J Dermatol 2020 Jun 22. Epub 2020 Jun 22.

Departments of, Department of, Dermatology, Hospital Universitari Arnau de Vilanova de Lleida, Catalonia, Spain.

Australas J Dermatol 2020 Jun 22. Epub 2020 Jun 22.

Department of Dermatology, Concord Repatriation General Hospital, Sydney, Australia.

Australas J Dermatol 2020 Jun 18. Epub 2020 Jun 18.

Dermatology Department, Mater Misericordiae University Hospital, Dublin 7, Ireland.

Australas J Dermatol 2020 Jun 16. Epub 2020 Jun 16.

Department of Dermatology, Hospital Universitario de Móstoles, Madrid, Spain.

Topical timolol has been shown to be effective on treatment of Kaposi sarcoma. We present the case of a 72-year-old man with classic Kaposi sarcoma on upper limbs, treated with topical timolol 0.5% twice a day with a pruritic eruption on areas of application. Read More

Australas J Dermatol 2020 Jun 16. Epub 2020 Jun 16.

Department of Dermatology, National University Health System, National University Hospital, Singapore, Singapore.

Australas J Dermatol 2020 Jun 16. Epub 2020 Jun 16.

Department of Dermatology, West China Hospital, Sichuan University, Chengdu, China.

Australas J Dermatol 2020 Jun 16. Epub 2020 Jun 16.

Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences (TUMS), Tehran, Iran.

Australas J Dermatol 2020 Jun 16. Epub 2020 Jun 16.

Northern Clinical School, University of Sydney, Sydney, NSW, Australia.

Background: There is limited information about the type of skin disease in Timor-Leste. In order to determine the type and magnitude of skin disease in Timor-Leste, we conducted a cross-sectional point prevalence study of 271 patients from rural and urban Timor-Leste. The aim of the study was to estimate the magnitude and burden of dermatological disease. Read More

Australas J Dermatol 2020 Jun 14. Epub 2020 Jun 14.

Division of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.

Background And Objectives: Leiomyosarcoma of skin (LMS) can be sub-classified on pathology appearances as Dermal or Subcutaneous. The aim of this study was to provide treatment recommendations for these uncommon tumours.

Methods: A retrospective review of all patients with dermal and subcutaneous leiomyosarcoma managed at the Peter MacCallum Cancer Centre, Australia from January 2003 to December 2018 was performed. Read More

Australas J Dermatol 2020 Jun 10. Epub 2020 Jun 10.

Dermatology Department, Centro Hospital e Universitário do Porto, Porto, Portugal.

Epidermolysis bullosa pruriginosa, a genetic mechanobullous disease, manifests at birth or late in life and is characterised by intense pruritus, resulting in lichenified or nodular prurigo-like lesions and scarring most prominent on the shins. Treatment is unsatisfactory. We report a patient treated with success using a combination of topical and systemic agents. Read More

Australas J Dermatol 2020 Jun 3. Epub 2020 Jun 3.

Department of Dermatology, Şişli Etfal Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.

Australas J Dermatol 2020 Jun 3. Epub 2020 Jun 3.

Skin Health Institute, Carlton, Victoria, Australia.

Australas J Dermatol 2020 Jun 2. Epub 2020 Jun 2.

Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Extranodal natural killer/T-cell lymphoma (ENKTL) is a rare but aggressive cancer characterised by angiocentric and angiodestructive infiltration by NK-cells, or cytotoxic T-cell types. Histopathologically, ENKTL shows a multinodular or diffuse infiltration localised to vascular structures, resulting in angiodestruction and necrosis. We present a patient with an initially suspected diagnosis of benign interface dermatitis with a differential diagnosis of mycosis fungoides that was later found to be an aggressive extranodal natural killer/T-cell lymphoma of a nasal type and with a dismal prognosis. Read More

Australas J Dermatol 2020 Jun 1. Epub 2020 Jun 1.

Department of Dermatology, Zhongshan Hospital Xiamen University, Xiamen, Fujian, China.

We reported a Chinese pedigree with scrotal Dowling-Degos disease and evaluated the phenotypic and genotypic characteristics. In affected cases, pigmented macules were identified on the scrotum. The rashes increased, and the colour deepened progressively. Read More

Australas J Dermatol 2020 May 29. Epub 2020 May 29.

Department of Pathology, AIIMS, Bhubaneswar, India.

Australas J Dermatol 2020 May 28. Epub 2020 May 28.

Department of Dermatology, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Australas J Dermatol 2020 May 21. Epub 2020 May 21.

Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan Central Hospital of Shanxi Medical University, Taiyuan, China.

Objectives: Psoriasis is an immunodeficient skin disorder, and its exact pathogenesis is unclear. Monozygotic twins are presumed to be genetically identical, and their phenotypic differences may be due to transcriptional regulation or epigenome factors. To explain the inconsistency between twins, we have collected 3 pairs of monozygotic twins who are discordant for psoriasis. Read More

Australas J Dermatol 2020 May 22. Epub 2020 May 22.

Central Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.

Australas J Dermatol 2020 May 21. Epub 2020 May 21.

Sinclair Dermatology, East Melbourne, Vic., Australia.

Australas J Dermatol 2020 May 20. Epub 2020 May 20.

Occupational Dermatology Research and Education Centre, Skin Health Institute, Carlton, Victoria, Australia.

Australas J Dermatol 2020 May 19. Epub 2020 May 19.

Department of Dermatology, Faculdade de Medicina do ABC, Santo André, Brazil.

Australas J Dermatol 2020 May 18. Epub 2020 May 18.

Department of Dermatology, Peking University Third Hospital, Beijing, China.

Objectives: The study examines the changes in dermoscopic features of actinic keratosis (AK) after photodynamic therapy, and delineates the association between AK dermoscopic and histopathological findings.

Methods: A total of 21 patients (23 lesions) with pathologically confirmed actinic keratosis who received 5-aminolaevulinic acid (ALA) photodynamic therapy (ALA-PDT) were enrolled. The numbers of PDT treatments were: 1, n = 1; 2, n = 2; 3, n = 10; 4, n = 6; 5, n = 2; 6, n = 2). Read More

Australas J Dermatol 2020 May 18. Epub 2020 May 18.

Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

We compared the clinicopathological features and prognosis between 16 amelanotic acral melanomas versus 56 pigmented acral melanomas. Amelanotic acral melanomas showed a thicker Breslow thickness (all had a Breslow thickness > 1 mm), more frequent ulceration (15/16, 93.7%) and lower HMB-45 positive rate than pigmented acral melanomas. Read More

Australas J Dermatol 2020 May 18. Epub 2020 May 18.

National Skin Center, Singapore, Singapore.

Australas J Dermatol 2020 May 18. Epub 2020 May 18.

Department of Pharmacology, University School of Medicine, Zagreb, Croatia.

Australas J Dermatol 2020 May 18. Epub 2020 May 18.

Australasian College of Dermatologists E-Health Committee, Brisbane, QLD, Australia.

Telemedicine is rapidly becoming ubiquitous as the medical profession adjusts its practice to provide optimal care to patients in the context of the COVID19 pandemic. The ability to provide accurate dermatological advice via telemedicine is dependent on the receipt of high-quality clinical images and accurate clinical context, on which clinicians receive little education during medical school and subsequent training. Clinicians can improve their capture, delivery and storage of images using the CLOSE-UP acronym, which encapsulates important considerations in the clinical photography process. Read More

Australas J Dermatol 2020 May 17. Epub 2020 May 17.

Division of Dermatology, Department of Medicine, University of Louisville, Louisville, Kentucky, USA.

Australas J Dermatol 2020 May 17. Epub 2020 May 17.

Mater Hospital, South Brisbane, Queensland, Australia.

Shave excision is a simple and cost-effective technique for the removal of suitable skin lesions. We performed a prospective study over six months, collecting data from pigmented lesions that were treated with shave excision by dermatologists. Only shave excisions with the intent to remove the lesion in toto were included. Read More