3,333 results match your criteria Austral Journal Of Veterinary Sciences[Journal]


Anverenes B⁻E, New Polyhalogenated Monoterpenes from the Antarctic Red Alga .

Mar Drugs 2019 Apr 17;17(4). Epub 2019 Apr 17.

Department of Chemistry, University of South Florida, 4202 E. Fowler Ave., CHE205, Tampa, FL 33620, USA.

The subtidal red alga was collected from the Western Antarctic Peninsula during the 2011 and 2017 austral summers. Bulk collections from specific sites corresponded to chemogroups identified by Young et al. in 2013. Read More

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http://dx.doi.org/10.3390/md17040230DOI Listing

Reconstructions of the dark-energy equation of state and the inflationary potential.

Gen Relativ Gravit 2018 19;50(7):82. Epub 2018 Jun 19.

2Instituto de Ciencias Físicas y Matemáticas, Universidad Austral de Chile, Valdivia, Chile.

We use a mathematical approach based on the constraints systems in order to reconstruct the equation of state and the inflationary potential for the inflaton field from the observed spectral indices for the density perturbations and the tensor to scalar ratio . From the astronomical data, we can observe that the measured values of these two indices lie on a two-dimensional surface. We express these indices in terms of the Hubble slow-roll parameters and we assume that . Read More

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http://link.springer.com/10.1007/s10714-018-2402-4
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http://dx.doi.org/10.1007/s10714-018-2402-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434992PMC
June 2018
1 Read

On the occurrence and ecology of Glaucus atlanticus Forster, 1777 (Mollusca: Nudibranchia) along the Southwestern Atlantic coast.

An Acad Bras Cienc 2019 8;91(1):e20180154. Epub 2019 Apr 8.

Laboratório de Ecologia do Zooplâncton, Instituto de Oceanografia, Universidade Federal do Rio Grande/FURG, Av. Itália, Km 8, Campus Carreiros, 96203-900, Rio Grande, RS, Brazil.

Unlike the majority of the nudibranchs, Glaucidae lives adrift at the sea surface within Tropical and Subtropical ocean basins, feeding on cnidarians or using them to attach their egg strings as a reproductive strategy. The latitudinal distribution of Glaucus atlanticus throughout the Brazilian Province is influenced by the Brazil current and, in its austral limit, by seasonal shifts in the Subtropical Convergence Zone (especially under the influence of ENSO El Niño events). Once over the shelf, seasonal wind patterns and meteorological events can force a passive displacement of the species towards the shore. Read More

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http://dx.doi.org/10.1590/0001-3765201920180154DOI Listing

Schizophrenia-like reduced sensorimotor gating in intact inbred and outbred rats is associated with decreased medial prefrontal cortex activity and volume.

Neuropsychopharmacology 2019 Apr 16. Epub 2019 Apr 16.

Department of Psychiatry & Forensic Medicine, Institute of Neurosciences, Universitat Autònoma de Barcelona, Bellaterra, 08193, Barcelona, Spain.

Prepulse inhibition (PPI) of startle response is a measure of sensorimotor gating that is impaired in schizophrenia and in many other clinical conditions. Rat models using pharmacological or surgical strategies reveal that PPI is modulated by the cortico-striatal-pallido-thalamic (CSPT) circuit. Here, we explore whether spontaneous variation in PPI in intact inbred and outbred rats is associated with functional and structural differences in the CSPT circuit. Read More

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http://dx.doi.org/10.1038/s41386-019-0392-xDOI Listing
April 2019
1 Read

Interleukin-17A blockade reduces albuminuria and kidney injury in an accelerated model of diabetic nephropathy.

Kidney Int 2019 Mar 8. Epub 2019 Mar 8.

Cellular and Molecular Biology in Renal and Vascular Pathology Laboratory, Instituto de Investigación Sanitaria Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain.

Diabetic nephropathy (DN) is one of the most common complications of diabetes, and currently the first end-stage renal disease worldwide. New strategies to treat DN using agents that target inflammatory pathways have attracted special interest. Recent pieces of evidences suggest a promising effect of IL-17A, the Th17 effector cytokine. Read More

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http://dx.doi.org/10.1016/j.kint.2018.12.031DOI Listing
March 2019
2 Reads

Polyphenols obtained from Didymosphenia geminata (Lyngbye) Schmith altered the viability and proliferation of salmonids cells lines SHK-1 and CHSE-214.

Aquat Toxicol 2019 Apr 1;211:141-147. Epub 2019 Apr 1.

Laboratorio Biología Celular y Molecular Aplicada, Facultad de Ciencias, Universidad Mayor, Temuco, Chile. Electronic address:

Didymosphenia geminata (Lyngbye) Schmidt, also referred to as Didymo, is an invasive diatom that forms nuisance mats. Since it was first reported in our country in approximately 2010, Didymo has expanded and colonized different rivers in the Zona Austral region of Chile. Its biology and effects on ecosystems are still being studied because Didymo is an invasive algal mat that forms in a range of systems from oligotrophic austral rivers to more subtropical systems. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0166445X193005
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http://dx.doi.org/10.1016/j.aquatox.2019.03.022DOI Listing
April 2019
3 Reads

A multicenter study to predict neonatal survival according to lung-to-head ratio and liver herniation in fetuses with left Congenital Diaphragmatic Hernia (CDH): hidden mortality from the Latin American CDH Study Group Registry.

Prenat Diagn 2019 Apr 13. Epub 2019 Apr 13.

Unidad de Cirugía Fetal, Hospital de Especialidades del Niño y la Mujer, Queretaro, Mexico.

Objective: To evaluate natural history of fetuses congenital diaphragmatic hernia (CDH) prenatally diagnosed in countries where termination of pregnancy is not legally allowed and to predict neonatal survival according to lung area and liver herniation.

Methods: Prospective study including antenatally diagnosed CDH cases managed expectantly during pregnancy in six tertiary Latin American centres. The contribution of the observed/expected lung-to-head ratio (O/E-LHR) and liver herniation in predicting neonatal survival was assessed. Read More

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http://dx.doi.org/10.1002/pd.5458DOI Listing

Bovine fetal mesenchymal stem cells exert antiproliferative effect against mastitis causing pathogen Staphylococcus aureus.

Vet Res 2019 Apr 11;50(1):25. Epub 2019 Apr 11.

Department of Animal Production Science, Faculty of Veterinary Medicine, University of Chile, 8820808, Santiago, Chile.

Staphylococcus aureus is the most commonly isolated pathogen from clinical bovine mastitis samples and a difficult pathogen to combat. Mesenchymal stem cells (MSC) are multipotent progenitor cells equipped with a variety of factors that inhibit bacterial growth. The aim of the present study was to evaluate the in vitro antibacterial potential against S. Read More

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http://dx.doi.org/10.1186/s13567-019-0643-1DOI Listing

Sumoylation of nucleoprotein (NP) mediated by activation of NADPH oxidase complex is a consequence of oxidative cellular stress during infection by Infectious salmon anemia (ISA) virus necessary to viral progeny.

Virology 2019 Mar 20;531:269-279. Epub 2019 Mar 20.

Facultad de Ciencias, Instituto de Bioquímica y Microbiología, Universidad Austral de Chile, Campus Isla Teja S/N, Valdivia, Chile. Electronic address:

The study evaluated the effects of nucleoprotein viral and the infectious virus in SHK-1 cells. The results show a strong respiratory burst activation and the induction of p47phox, SOD, GLURED, and apoptotic genes. Additionally, the cells alter the profile of SUMOylated proteins by the effect of transfection and infection experiments. Read More

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http://dx.doi.org/10.1016/j.virol.2019.03.012DOI Listing
March 2019
1 Read

Pericytes Favor Oligodendrocyte Fate Choice in Adult Neural Stem Cells.

Front Cell Neurosci 2019 27;13:85. Epub 2019 Mar 27.

Laboratory of Stem Cells and Neuroregeneration, Institute of Anatomy, Histology and Pathology, Faculty of Medicine, Universidad Austral de Chile, Valdivia, Chile.

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS). Upon demyelination, oligodendrocyte progenitor cells (OPCs) are activated and they proliferate, migrate and differentiate into myelin-producing oligodendrocytes. Besides OPCs, neural stem cells (NSCs) may respond to demyelination and generate oligodendrocytes. Read More

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https://www.frontiersin.org/article/10.3389/fncel.2019.00085
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http://dx.doi.org/10.3389/fncel.2019.00085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446960PMC
March 2019
2 Reads

Is the Evidence Provided by the SPRINT Trial Solid Enough to Support a Systolic Blood Pressure Threshold of 120 mmHg?

Rev Esp Cardiol (Engl Ed) 2019 Apr 7. Epub 2019 Apr 7.

Centro de Hipertensión Arterial y Envejecimiento Vascular, Hospital Universitario Austral, Pilar, Buenos Aires, Argentina.

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https://linkinghub.elsevier.com/retrieve/pii/S18855857193007
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http://dx.doi.org/10.1016/j.rec.2019.01.011DOI Listing
April 2019
1 Read

Analysis of the temporal-spatial changes in surface radiation budget over the Antarctic sea ice region.

Sci Total Environ 2019 May 21;666:1134-1150. Epub 2019 Feb 21.

Chinese Antarctic Center of Surveying and Mapping, Wuhan University, Wuhan 430079, China.

The surface radiation budget (SRB) of the Antarctic sea ice region (ASIR) is important for the climate change in Antarctica, which partly explains the global warming. Long-term (1982-2015) satellite-derived (EUMETSAT Satellite Application Facility on Climate Monitoring, CLARA-A2) and reanalysis (European Centre for Medium-Range Weather Forecasts, ERA-Interim) datasets provided high quality and global coverage surface radiation products, which enabled us to quantify the SRB of the ASIR and widen our understanding of the polar climate. The downwelling longwave (LW) and shortwave (SW) radiation from the two datasets were validated at two Baseline Surface Radiation Network Stations (i. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.02.264DOI Listing

A double-blind, randomized, placebo-controlled study to assess the efficacy of Andrographis paniculata standardized extract (ParActin®) on pain reduction in subjects with knee osteoarthritis.

Phytother Res 2019 Apr 10. Epub 2019 Apr 10.

Institute of Pharmacology and Morphophysiology, Facultad de Ciencias Veterinarias Universidad Austral de Chile, Valdivia, Chile.

Andrographis paniculata Wall (Acanthaceae) is becoming more recognized for its anti-inflammatory and antioxidant properties. A randomized, double-blind, placebo-controlled study was conducted to assess the efficacy of an andrographolide-containing supplement, ParActin® (300 and 600 mg daily), on Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain reduction in patients with knee osteoarthritis. Joint stiffness, physical function, changes in the SF-36 quality of life questionnaire, a fatigue scale, and safety were also evaluated. Read More

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http://dx.doi.org/10.1002/ptr.6339DOI Listing
April 2019
2 Reads

The "Brain Stress Timing" phenomenon and other misinterpretations of randomized clinical trial on aneurysmal subarachnoid hemorrhage.

Neural Regen Res 2019 Aug;14(8):1364-1366

Division of Cerebrovascular and Skull Base Neurosurgery, Institute of Neurosurgery Dr Asenjo, Santiago, Chile.

Clipping and coiling are currently the two alternatives in treatment of ruptured cerebral aneurysms. In spite of some meritorious analysis, further discussion is helpful to understand the actual state of art. Retreatment and rebleeding rates clearly favors clipping, although short-term functional outcome seems to be beneficial for clipping, while this different is not such if we perform the comparison at a longer follow up. Read More

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http://www.nrronline.org/text.asp?2019/14/8/1364/253513
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http://dx.doi.org/10.4103/1673-5374.253513DOI Listing
August 2019
3 Reads

Basal polyphagan beetles in mid-Cretaceous amber from Myanmar: biogeographic implications and long-term morphological stasis.

Proc Biol Sci 2019 Jan;286(1894):20182175

8 Division of Entomology, Natural History Museum, University of Kansas , Lawrence, KS 66045 , USA.

The origin and early evolutionary history of polyphagan beetles have been largely based on evidence from the derived and diverse 'core Polyphaga', whereas little is known about the species-poor basal polyphagan lineages, which include Scirtoidea (Clambidae, Decliniidae, Eucinetidae, and Scirtidae) and Derodontidae. Here, we report two new species Acalyptomerus thayerae sp. nov. Read More

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http://dx.doi.org/10.1098/rspb.2018.2175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367173PMC
January 2019

First sighting of a tropical benthic reef shark species at Rapa Nui: chance dispersal or a sign of things to come?

J Fish Biol 2019 Apr 9. Epub 2019 Apr 9.

Millennium Nucleus for Ecology and Sustainable Management of Oceanic Islands (ESMOI), Facultad de Ciencias del Mar, Universidad Católica del Norte, Coquimbo, Chile.

On 20 December, 2017, a mature Triaenodon obesus was observed at Hanga Roa Bay, Rapa Nui (Easter Island) at c.18 m depth. This observation increases both the range of T. Read More

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http://dx.doi.org/10.1111/jfb.13977DOI Listing

Shared and unique features of bacterial communities in native forest and vineyard phyllosphere.

Ecol Evol 2019 Mar 20;9(6):3295-3305. Epub 2019 Feb 20.

Instituto de Ecología & Biodiversidad (IEB-Chile) Santiago Chile.

Phyllosphere bacteria have received little attention despite their important roles in shaping plant performance traits. In this study, we characterize the bacterial communities on leaves of native trees inhabiting sclerophyllous forests in central Chile, one of the world's biodiversity hotspots. Additionally, we provide profiles of bacterial communities on grape leaves and berries of organic and conventional vineyards. Read More

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http://dx.doi.org/10.1002/ece3.4949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434556PMC

Electrically-Responsive Reversible Polyketone/MWCNT Network through Diels-Alder Chemistry.

Polymers (Basel) 2018 Sep 28;10(10). Epub 2018 Sep 28.

Department of Chemical Product Engineering, ENTEG, University of Groningen, Nijenborgh 4, 9747AG Groningen, The Netherlands.

This study examines the preparation of electrically conductive polymer networks based on furan-functionalised polyketone (PK-Fu) doped with multi-walled carbon nanotubes (MWCNTs) and reversibly crosslinked with bis-maleimide (B-Ma) via Diels-Alder (DA) cycloaddition. Notably, the incorporation of 5 wt.% of MWCNTs results in an increased modulus of the material, and makes it thermally and electrically conductive. Read More

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http://dx.doi.org/10.3390/polym10101076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403874PMC
September 2018

MESENCHYMAL STEM CELL THERAPY IMPROVES SPATIAL MEMORY AND HIPPOCAMPAL STRUCTURE IN AGING RATS.

Behav Brain Res 2019 Apr 2. Epub 2019 Apr 2.

INIBIOLP-Pathology B, School of Medicine, National University of La Plata, Argentina; Department of Histology and of Embryology B, School of Medicine, National University of La Plata, Argentina. Electronic address:

There is a growing interest in the potential of mesenchymal stem cells (MSCs) for implementing regenerative medicine in the brain as they have shown neurogenic and immunomodulatory activities. We assessed the effect of intracerebroventricular (icv) administration of human bone marrow-derived MSCs (hBM-MSCs) on spatial memory and hippocampal morphology of senile (27 months) female rats, using 3-months-old counterparts as young controls. Half of the animals were injected in the lateral ventricles (LV) with a suspension containing 5 × 10hBM-MSCs in 8 µl per side. Read More

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http://dx.doi.org/10.1016/j.bbr.2019.04.001DOI Listing
April 2019
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Redescription of Dichelyne ( Cucullanellus) Dichelyneformis (Nematoda: Cucullanidae) and Description of a New Congeneric Species in Eleginops maclovinus (Pisces: Eleginopsidae) Collected in the Bay of Corral, Chile.

J Parasitol 2019 Apr;105(2):263-270

Instituto de Parasitología, Facultad de Medicina, Edificio de Ciencias Biomédicas, Campus Isla Teja, Universidad Austral de Chile, Box 567, Valdivia, Chile.

Dichelyne ( Cucullanellus) dichelyneformis ( Szidat, 1950 ) Petter, 1974 , was collected in the intestine of the rock cod, Eleginops maclovinus, in the Bay of Corral, Chile, and redescribed based on light and scanning electron microscopy. The correct arrangement of caudal papillae and post deirids, the shape of gubernaculum, and the morphology and number of denticles surrounding the oral opening are described for the first time. These characteristics along with the excretory pore position, size of spicules, and presence of a nodular thickening near the distal end of the spicules differentiate D. Read More

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New therapies in development for the management of non-infectious uveitis: a review.

Clin Exp Ophthalmol 2019 Apr 2. Epub 2019 Apr 2.

Byers Eye Institute, Stanford University, Palo Alto, USA.

Uveitis is a spectrum of inflammatory disorders characterised by ocular inflammation and is one of the leading causes of preventable visual loss. The main aim of the treatment of uveitis is to control the inflammation, prevent recurrences of the disease, and preserve vision while minimizing the adverse effects associated with the therapeutic agents. Initial management of uveitis relies heavily on the use of corticosteroids. Read More

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http://dx.doi.org/10.1111/ceo.13511DOI Listing
April 2019
4 Reads

Pericytes in the Retina.

Adv Exp Med Biol 2019 ;1122:1-26

Department of Ophthalmology, University Clinic of Ophthalmology and Optometry, Research Program for Experimental Ophthalmology and Glaucoma Research, Paracelsus Medical University/SALK, Salzburg, Austria.

Pericytes (PCs) are specialized cells located abluminal of endothelial cells (ECs) on capillaries, embedded within the same basement membrane. They are essential regulators of vascular development, remodeling, and blood-retina-barrier (BRB) tightness and are therefore important components to maintain tissue homeostasis. The perivascular localization and expression of contractile proteins suggest that PCs participate in capillary blood flow regulation and neurovascular coupling. Read More

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http://link.springer.com/10.1007/978-3-030-11093-2_1
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http://dx.doi.org/10.1007/978-3-030-11093-2_1DOI Listing
January 2019
5 Reads

Metabolic disturbances in synovial fluid are involved in the onset of synovitis in heifers with acute ruminal acidosis.

Sci Rep 2019 Apr 1;9(1):5452. Epub 2019 Apr 1.

Laboratory of Inflammation Pharmacology, Faculty of Veterinary Science, Institute of Pharmacology and Morphophysiology, Universidad Austral de Chile, Valdivia, Chile.

Acute ruminal acidosis (ARA) is the result of increased intake of highly fermentable carbohydrates, which frequently occurs in dairy cattle and is associated with aseptic polysynovitis. To characterise the metabolic changes in the joints of animals with ARA, we performed an untargeted gas chromatography-mass spectrometry (GC-MS)-based metabolomic analysis of synovial fluid. Seven heifers were challenged with an intraruminal oligofructose overload (13 g/kg of body weight [BW]) dissolved in water. Read More

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http://www.nature.com/articles/s41598-019-42007-1
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http://dx.doi.org/10.1038/s41598-019-42007-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443794PMC
April 2019
6 Reads

Means and Long-Term Trends of Global Coastal Zone Precipitation.

Authors:
Scott Curtis

Sci Rep 2019 Apr 1;9(1):5401. Epub 2019 Apr 1.

Distinguished Professor in Natural Sciences and Mathematics, Department of Geography, Planning, and Environment, East Carolina University, Greenville, NC, 27858, USA.

Precipitation in the coastal zone is important to the socio-economic and ecological well-being of the world. Meteorologically, precipitation is generated by unique mechanisms at the land-sea interface, which is why coastal zone precipitation is not well resolved by global climate models. Yet, to date, much more effort has been placed in analyzing global precipitation over the oceans and land. Read More

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http://dx.doi.org/10.1038/s41598-019-41878-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443665PMC
April 2019
1 Read

The Trichopterygini (Lepidoptera, Geometridae) of Austral South America: description of new species from Chile.

Zookeys 2019 19;832:91-111. Epub 2019 Mar 19.

Departamento de Zoología, Facultad de Ciencias Naturales y Oceanográficas, Universidad de Concepción, Casilla 160-C, Concepción, Chile.

Four new species belonging to the genera Butler, Parra, Parra, and Parra from south-central Chile are described. The species are Ramos-González & Parra, , Ramos-González & Parra, , Ramos-González & Parra, , and Ramos-González & Parra, The genus Warren is reassigned to tribe Trichopterygini and Ramos-González & Parra, is described. Comparative diagnosis for all new species are provided, and illustrations of genitalia and the wing venation of the males for all new described species are given. Read More

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http://dx.doi.org/10.3897/zookeys.832.30851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435600PMC

Reply to «Spontaneous acute epidural haematoma of the cervical spine with an atypical onset resembling ictal symptom».

Neurologia 2019 Mar 27. Epub 2019 Mar 27.

Wester University, London, Ontario, Canadá.

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http://dx.doi.org/10.1016/j.nrl.2018.12.009DOI Listing
March 2019
1 Read

Early differential gene expression in beef Longissimus thoracis muscles from carcasses with normal (<5.8) and high (>5.9) ultimate pH.

Meat Sci 2019 Jul 19;153:117-125. Epub 2019 Mar 19.

Instituto de Farmacología y Morfofisiología, Facultad de Ciencias Veterinarias, Universidad Austral de Chile, Valdivia, Chile. Electronic address:

The objective of this study was to investigate early postmortem (0.5 h) gene expression in beef Longissimus thoracis (LT) muscles from carcasses with NORMAL (<5.8) and HIGH (>5. Read More

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http://dx.doi.org/10.1016/j.meatsci.2019.03.013DOI Listing
July 2019
1 Read

When flowering plants ruled Antarctica: evidence from Cretaceous pollen grains.

New Phytol 2019 Mar 29. Epub 2019 Mar 29.

Centro Austral de Investigaciones Científicas (CADIC-CONICET), B. Houssay 200, 9410, Ushuaia, Tierra del Fuego, Argentina.

The replacement of seed-free plants and gymnosperms by flowering plants during the Cretaceous is one of the most important biotic events in the evolution of life. However, the magnitude of this global turnover remains largely unknown. -Here we present sampling-standardized diversity estimates from a high resolution palynological record of the Late Cretaceous (85-66 Ma) from Antarctica, in the context of the past climatic events. Read More

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http://dx.doi.org/10.1111/nph.15823DOI Listing

Acute syphilitic posterior placoid chorioretinopathy: An infectious or autoimmune disease?

Am J Ophthalmol Case Rep 2019 Jun 8;14:70-73. Epub 2019 Mar 8.

Department of Ophthalmology, Hospital Universitario Austral, Argentina.

Purpose: To report a case of acute syphilitic posterior placoid chorioretinopathy (ASPPC) that demonstrated partial resolution with immunosuppressive therapy secondary to a misdiagnosis as Behçet's disease followed by a relapse which was successfully treated with the appropriate treatment.

Observations: A 34-year-old female patient presented to our service with complaints of decreased vision in the left eye (OS). She initially developed similar symptoms seven months prior to presentation and was diagnosed as Behçet's disease based on the clinical picture of papillitis, vasculitis and placoid chorioretinitis in the posterior pole of OS. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423698PMC
June 2019
1 Read

Oceanographic moorings as year-round laboratories for investigating growth performance and settlement dynamics in the Antarctic scallop (E. A. Smith, 1902).

PeerJ 2019 21;7:e6373. Epub 2019 Mar 21.

Istituto di Scienze Marine, Italian National Research Council (CNR), La Spezia, Italy.

Background: Oceanographic moorings (OMs) are standard marine platforms composed of wires, buoys, weights and instruments, and are used as in situ observatories to record water column properties. However, OMs are also comprised of hard substrates on which a variety of invertebrates can settle when they encounter these structures along their dispersal routes. In this contribution, we studied the fouling communities found on two OMs deployed in the Ross Sea (Antarctica). Read More

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http://dx.doi.org/10.7717/peerj.6373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431546PMC

Reproductive success delays moult phenology in a polar mammal.

Sci Rep 2019 Mar 26;9(1):5221. Epub 2019 Mar 26.

Biological Sciences, University of Alaska Anchorage, 3101 Science Circle, Anchorage, Alaska, 99508, USA.

Animals can respond to dynamic environments through phenological plasticity of life history events; however, changes in one part of the annual cycle can diminish the success of subsequent life history events. Our aims were to determine the associations between reproduction and moult phenology across years and to quantify phenological plasticity across varying environmental conditions. We conducted demographic surveys of 4,252 flipper-tagged Weddell seals (Leptonychotes weddellii) in the Ross Sea, Antarctica during four austral summers. Read More

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http://dx.doi.org/10.1038/s41598-019-41635-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435649PMC

Exponential consensus ranking improves the outcome in docking and receptor ensemble docking.

Sci Rep 2019 Mar 26;9(1):5142. Epub 2019 Mar 26.

Biophysics of Tropical Diseases Max Planck Tandem Group, University of Antioquia, Medellín, Colombia.

Consensus-scoring methods are commonly used with molecular docking in virtual screening campaigns to filter potential ligands for a protein target. Traditional consensus methods combine results from different docking programs by averaging the score or rank of each molecule obtained from individual programs. Unfortunately, these methods fail if one of the docking programs has poor performance, which is likely to occur due to training-set dependencies and scoring-function parameterization. Read More

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http://dx.doi.org/10.1038/s41598-019-41594-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435795PMC
March 2019
1 Read

Inferring parental gonadal mosaicism in LMNA-associated muscular dystrophy by ultra-deep next generation sequencing: A sensitive approach providing valuable information for genetic counseling.

Am J Med Genet A 2019 Mar 26. Epub 2019 Mar 26.

Consultorio de Neurogenética, Centro Universitario de Neurología y División Neurología, Hospital J.M. Ramos Mejía, Facultad de Medicina, UBA, Buenos Aires, Argentina.

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http://dx.doi.org/10.1002/ajmg.a.61135DOI Listing

Dairy science and health in the tropics: challenges and opportunities for the next decades.

Trop Anim Health Prod 2019 Mar 26. Epub 2019 Mar 26.

LEAF, Instituto Superior de Agronomia, Universidade de Lisboa, Tapada da Ajuda, 1349-017, Lisbon, Portugal.

In the next two decades, the world population will increase significantly; the majority in the developing countries located in the tropics of Africa, Asia, Latin America, and the Caribbean. To feed such a population, it is necessary to increase the availability of food, particularly high-value animal protein foods produced locally, namely meat and dairy products. Dairy production in tropical regions has a lot of growth potential, but also poses a series of problems, particularly as dairy production systems were developed in temperate countries and in most cases are difficult to implement in the tropics. Read More

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http://dx.doi.org/10.1007/s11250-019-01866-6DOI Listing
March 2019
1 Read

Role of adherens junctions and apical-basal polarity of neural stem/progenitor cells in the pathogenesis of neurodevelopmental disorders: a novel perspective on congenital Zika syndrome.

Transl Res 2019 Mar 5. Epub 2019 Mar 5.

Center for Interdisciplinary Studies on the Nervous System (CISNe), Universidad Austral de Chile, Valdivia Chile; Centro de Investigación Biomédica (CIB), Facultad de Medicina, Universidad de los Andes, Santiago, Chile. Electronic address:

Radial glial cells (RGCs) are the neural stem/progenitor cells (NSPCs) that give rise to most of neurons and glial cells that constitute the adult central nervous system. A hallmark of RGCs is their polarization along the apical-basal axis. They extend a long basal process that contacts the pial surface and a short apical process to the ventricular surface. Read More

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http://dx.doi.org/10.1016/j.trsl.2019.02.014DOI Listing
March 2019
2 Reads

Increased expression of mitochondrial sodium-coupled ascorbic acid transporter-2 (mitSVCT2) as a central feature in breast cancer.

Free Radic Biol Med 2019 Mar 19;135:283-292. Epub 2019 Mar 19.

Departamento de Fisiopatología, Facultad de Ciencias Biológicas, Universidad de Concepción, Barrio Universitario s/n, PO Box 160C, Concepción, Chile. Electronic address:

The potential role of vitamin C in cancer prevention and treatment remains controversial. While normal human cells obtain vitamin C as ascorbic acid, the prevalent form of vitamin C in vivo, the uptake mechanisms by which cancer cells acquire vitamin C has remained unclear. The aim of this study is to characterize how breast cancer cells acquire vitamin C. Read More

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http://dx.doi.org/10.1016/j.freeradbiomed.2019.03.015DOI Listing

Antioxidant, Gastroprotective, Cytotoxic Activities and UHPLC PDA-Q Orbitrap Mass Spectrometry Identification of Metabolites in Decoction.

Molecules 2019 Mar 19;24(6). Epub 2019 Mar 19.

Instituto de Biotecnología-Instituto de Ciencias Básicas, Universidad Nacional de San Juan, Av. Libertador General San Martín 1109 (O), San Juan CP 5400, Argentina.

The decoction of the local plant is used as a digestive, gastroprotective, external cicatrizing agent and antiseptic in Argentine. A lyophilized decoction (BLD) from the aerial parts of this plant was evaluated regarding its anti-ulcer, antioxidant and cytotoxic activities and the bioactivities were supported by UHPLC-MS metabolome fingerprinting which revealed the presence of several small bioactive compounds. The antioxidant properties were evaluated by DPPH, TEAC, FRAP and lipoperoxidation inhibition in erythrocytes methods, and the antibacterial activity was evaluated according to the Clinical and Laboratory Standards Institute (CLSI) guidelines. Read More

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http://dx.doi.org/10.3390/molecules24061085DOI Listing

In vitro immunomodulatory activities of peptides derived from Salmo salar NK-lysin and cathelicidin in fish cells.

Fish Shellfish Immunol 2019 May 16;88:587-594. Epub 2019 Mar 16.

Biotechnology and Biopharmaceutical Laboratory, Pathophysiology Department, School of Biological Sciences, Universidad de Concepción, Victor Lamas 1290, P.O. Box 160-C, Concepción, Chile.

Antimicrobial peptides (AMPs) are amphipathic peptides, which play an important role in innate defence. These peptides are gene-encoded and either constitutively expressed and/or upregulated during an infection. NK-lysins are AMPs with a three-dimensional globular structure. Read More

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http://dx.doi.org/10.1016/j.fsi.2019.03.034DOI Listing
May 2019
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Docosahexaenoic acid and TUG-891 activate free fatty acid-4 receptor in bovine neutrophils.

Vet Immunol Immunopathol 2019 Mar 25;209:53-60. Epub 2019 Feb 25.

Laboratory of Molecular Pharmacology, Institute of Pharmacology, Faculty of Veterinary Science, Universidad Austral de Chile, Valdivia, Chile. Electronic address:

Fatty acids are well known metabolic intermediaries but also have a role in the immune response. Long-chain fatty acids such as omega-6 and -9 activate neutrophil function through free fatty acid (FFA)-1 receptor in bovines. Although omega-3 has also been suggested to influence neutrophil function, the details remain unclear. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01652427183039
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http://dx.doi.org/10.1016/j.vetimm.2019.02.008DOI Listing
March 2019
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A comprehensive study of epigenetic alterations in hepatocellular carcinoma identifies potential therapeutic targets.

J Hepatol 2019 Mar 14. Epub 2019 Mar 14.

Gene Therapy Laboratory, Instituto de Investigaciones en Medicina Traslacional, Facultad de Ciencias Biomédicas, CONICET, Universidad Austral, Derqui-Pilar, Argentina; Liver Unit, Hospital Universitario Austral, Derqui-Pilar, Argentina. Electronic address:

Background And Aims: A causal link has recently been established between epigenetic alterations and hepatocarcinogenesis, indicating that epigenetic inhibition may have therapeutic potential. We aimed to identify and target epigenetic modifiers that show molecular alterations in hepatocellular carcinoma (HCC).

Methods: We studied the molecular-clinical correlations of epigenetic modifiers including bromodomains, histone acetyltransferases, lysine methyltransferases and lysine demethylases in HCC using the Cancer Genome Atlas (TCGA) data of 365 HCC. Read More

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http://dx.doi.org/10.1016/j.jhep.2019.03.007DOI Listing

Arsenic exposure of child populations in Northern Argentina.

Sci Total Environ 2019 Jun 27;669:1-6. Epub 2019 Feb 27.

Instituto de Agroquímica y Tecnología de Alimentos (CSIC), C/ Agustín Escardino 7, 46980 Paterna, Valencia, Spain. Electronic address:

Chronic exposure to inorganic arsenic (As) is associated with numerous adverse effects. Argentina is one of the countries affected by arsenicism; however, there are few studies that evaluate inorganic As exposure and its effects on child population. The aim of this study is to evaluate exposure to As through water and food in child populations living in the provinces of Santiago del Estero and Chaco (n = 101), and to determine the impact of this exposure analysing biomarkers of exposure (urine and hair As contents) and effect [8-oxo-7,8-dihydro-2'-deoxyguanosine (8-OHdG)]. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00489697193092
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http://dx.doi.org/10.1016/j.scitotenv.2019.02.415DOI Listing
June 2019
10 Reads

Dehydration enhances innate immunity in a semiaquatic snake from the wet-dry tropics.

J Exp Zool A Ecol Integr Physiol 2019 Apr 14;331(4):245-252. Epub 2019 Mar 14.

School of Life Sciences, Arizona State University, Tempe, Arizona.

Dehydration is considered a physiological challenge, and many organisms live in environments that undergo periods of reduced water availability that can lead to dehydration. Recent studies have found a positive relationship between dehydration and innate immune function in animals adapted to xeric or semixeric environments. To explore the generality of this relationship, we examined the impact of dehydration on innate immune performance in water pythons (Liasis fuscus), a semiaquatic snake from the wet-dry tropics of Australia. Read More

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http://dx.doi.org/10.1002/jez.2260DOI Listing

Meditation focused on self-observation of the body impairs metacognitive efficiency.

Conscious Cogn 2019 Apr 11;70:116-125. Epub 2019 Mar 11.

École des Hautes Études en Sciences Sociales (EHESS), Paris, France; Subjective Correlates of Cognitive Mechanisms Group (EHESS/CNRS/ENS), PSL Research University, Paris, France; École Polytechnique, Palaiseau, France.

In the last decade of research on metacognition, the literature has been focused on understanding its mechanism, function and scope; however, little is known about whether metacognitive capacity can be trained. The specificity of the potential training procedure is in particular still largely unknown. In this study, we evaluate whether metacognition is trainable through generic meditation training, and if so, which component of meditation would be instrumental in this improvement. Read More

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http://dx.doi.org/10.1016/j.concog.2019.03.001DOI Listing

Measurement of the incidence of care-associated adverse events at the Department of Pediatrics of a teaching hospital.

Arch Argent Pediatr 2019 Apr;117(2):e106-e109

Unidad de Investigación del Dpto. de Calidad y Seguridad del Paciente. Hospital Austral, Pilar, Buenos Aires, Argentina.

Introduction: Adverse events may be detected using different screening tools. In the pediatric population, the Pediatric Trigger Tool looks for triggers in the medical record to detect preventable and non-preventable care-associated harm.

Objective: To measure the incidence of adverse events at the Department of Pediatrics using this tool. Read More

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http://dx.doi.org/10.5546/aap.2019.eng.e106DOI Listing

Antarctophthirus microchir infestation in synanthropic South American sea lion (Otaria flavescens) males diagnosed by a novel non-invasive method.

Parasitol Res 2019 Mar 14. Epub 2019 Mar 14.

Institute of Parasitology, Biomedical Research Center Seltersberg (BFS), Justus Liebig University Giessen, Schubertstr. 81, 35392, Giessen, Germany.

Antarctophthirus microchir is a sucking louse species belonging to the family Echinophthiriidae and has been reported to parasitize all species of the subfamily Otariinae, the sea lions. Former studies on this ectoparasite mainly required fixation, immobilization, or death of host species and especially examinations of adult male sea lions are still very rare. Between March and May 2018, adult individuals of a unique "urban" bachelor group of South American sea lions (Otaria flavescens) living directly in the city of Valdivia, Chile, were studied regarding their ectoparasite infestation status. Read More

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http://link.springer.com/10.1007/s00436-019-06273-2
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http://dx.doi.org/10.1007/s00436-019-06273-2DOI Listing
March 2019
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Sedimentary record from Patagonia, southern Chile supports cosmic-impact triggering of biomass burning, climate change, and megafaunal extinctions at 12.8 ka.

Sci Rep 2019 Mar 13;9(1):4413. Epub 2019 Mar 13.

Department of Earth Science and Marine Science Institute, University of California, Santa Barbara, CA, 93106, USA.

The Younger Dryas (YD) impact hypothesis posits that fragments of a large, disintegrating asteroid/comet struck North America, South America, Europe, and western Asia ~12,800 years ago. Multiple airbursts/impacts produced the YD boundary layer (YDB), depositing peak concentrations of platinum, high-temperature spherules, meltglass, and nanodiamonds, forming an isochronous datum at >50 sites across ~50 million km² of Earth's surface. This proposed event triggered extensive biomass burning, brief impact winter, YD climate change, and contributed to extinctions of late Pleistocene megafauna. Read More

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http://dx.doi.org/10.1038/s41598-018-38089-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416299PMC

Health monitoring during water scarcity in Mayotte, France, 2017.

BMC Public Health 2019 Mar 12;19(1):288. Epub 2019 Mar 12.

Santé publique France, cellule d'intervention en région océan Indien (CIRE OI) [French public health agency in the Indian Ocean Region], 2 bis avenue Georges Brassens CS 61002 - 97743 Saint-Denis cedex 9, Saint-Denis, La Réunion, France.

Background: During the 2016-2017 austral summer, unprecedented water scarcity was observed in the south of Mayotte, French island in the Indian Ocean. Therefore, authorities introduced restrictive measures to save the water of this part of the island. The rationing system affected over 65,000 people, for four months. Read More

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http://dx.doi.org/10.1186/s12889-019-6613-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416849PMC

Assessing the effects of human activities on the foraging opportunities of migratory shorebirds in Austral high-latitude bays.

PLoS One 2019 13;14(3):e0212441. Epub 2019 Mar 13.

Estación Experimental Quempillén, Chiloé, Facultad de Ciencias, Universidad Austral de Chile, Ancud, Chile.

Human presence at intertidal areas could impact coastal biodiversity, including migratory waterbird species and the ecosystem services they provide. Assessing this impact is therefore essential to develop management measures compatible with migratory processes and associated biodiversity. Here, we assess the effects of human presence on the foraging opportunities of Hudsonian godwits (Limosa haemastica, a trans-hemispheric migratory shorebird) during their non-breeding season on Chiloé Island, southern Chile. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212441PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415798PMC

S-nitrosylation and its role in breast cancer angiogenesis and metastasis.

Nitric Oxide 2019 Mar 9;87:52-59. Epub 2019 Mar 9.

Centro de Investigaciones del Sistema Nervioso (CISNe), Valdivia, Chile; Instituto de Inmunología, Facultad de Medicina, Universidad Austral de Chile, Valdivia, Chile. Electronic address:

S-nitrosylation, the modification by nitric oxide of free sulfhydryl groups in cysteines, has become an important regulatory mechanism in carcinogenesis and metastasis. S-nitrosylation of targets in tumor cells contributes to metastasis regulating epithelial to mesenchymal transition, migration and invasion. In the tumor environment, the role of S-nitrosylation in endothelium has not been addressed; however, the evidence points out that S-nitrosylation of endothelial proteins may regulate angiogenesis, adhesion of tumor cells to the endothelium, intra and extravasation of tumor cells and contribute to metastasis. Read More

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http://dx.doi.org/10.1016/j.niox.2019.03.002DOI Listing

Molecular detection of Bartonella in fleas (Hexapoda, Siphonaptera) collected from wild rodents (Cricetidae, Sigmodontinae) from Argentina.

Med Vet Entomol 2019 Mar 12. Epub 2019 Mar 12.

Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.

Bartonella are facultative intracellular Gram-negative bacteria, transmitted mainly by hematophagous arthropods, and the rodents act as a natural reservoir. Different species of Bartonella associated with rodents have been implicated as causing human disease. Studies from Argentina are scarce and no Bartonella from fleas have been reported previously. Read More

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http://dx.doi.org/10.1111/mve.12370DOI Listing