2 results match your criteria Austin journal of clinical ophthalmology[Journal]

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Increased ER stress as a mechanism of retinal neurovasculopathy in mice with severe hyperhomocysteinemia.

Austin J Clin Ophthalmol 2014 Jun;1(5):1023

Department of Cellular Biology and Anatomy, Medical College of Georgia, Georgia Regents University, Augusta, GA ; James and Jean Culver Vision Discovery Institute, Georgia Regents University, Augusta, GA ; Department of Ophthalmology, Medical College of Georgia, Georgia Regents University, Augusta, GA.

Hyperhomocysteinemia is implicated in retinal neurovascular diseases including arterial occlusive disease, venous occlusive disease and pseudoexfoliation glaucoma. The mechanism for these diseases is not known. Here we used hyperhomocysteinemic mice lacking the gene encoding cystathionine-beta-synthase () to examine whether ER stress could be a mechanism for the retinal neurovasculopathy reported in these mice. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287205PMC
June 2014
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Histopathology of the Retina from a Three Year-Old Suspected to Have Joubert Syndrome.

Austin J Clin Ophthalmol 2015 21;2(4). Epub 2015 Sep 21.

Cole Eye Institute, Cleveland Clinic, Cleveland, USA; Department of Ophthalmology, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, USA.

Purpose: To define the retinal pathology in a 3 year-old eye donor who died from complications of an undiagnosed genetic syndrome.

Methods: Eyes were fixed and analyzed using macroscopic fundus photography (MF), confocal scanning laser ophthalmoscopy (cSLO) and spectral-domain optical coherence tomography (SD-OCT). Small areas from the perifovea and periphery were processed for histology and indirect immunofluorescence, using antibodies specific to retinal proteins such as rhodopsin, cone arrestin, RPE65 and others. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061139PMC
September 2015
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