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    Is insufficient pulmonary air support the cause of dysphonia in chronic obstructive pulmonary disease?
    Auris Nasus Larynx 2018 Jan 8. Epub 2018 Jan 8.
    Otolaryngology Department, Faculty of Medicine, Sohag University, 82524, Egypt.
    Objective: Optimal pulmonary air support is essential pre-requisite for efficient phonation. The objective is to correlate pulmonary and vocal functions in chronic obstructive pulmonary disease (COPD) to find out whether the reduced pulmonary function per se could induce dysphonia.

    Methods: In this prospective case-control study, sixty subjects with stable COPD underwent evaluation of pulmonary and vocal functions. Read More

    Augmentation surgery on the cartilaginous portion of the vocal fold in a patient with cricoarytenoid joint ankylosis.
    Auris Nasus Larynx 2018 Jan 4. Epub 2018 Jan 4.
    Department of Otolaryngology, Head and Neck Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830-0011, Japan.
    Surgical management of cricoarytenoid joint (CAJ) ankylosis is challenging and has the risk of worsening voice quality. In the present case, augmentation surgery was performed on the cartilaginous portion of the vocal fold in a patient with CAJ ankylosis. A 24-year-old man sustained blunt trauma to the anterior neck three years prior to developing severe breathiness. Read More

    Typical sensory organization test findings and clinical implication in acute vestibular neuritis.
    Auris Nasus Larynx 2017 Dec 16. Epub 2017 Dec 16.
    Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, 86 Asanbyeongwon-gil, Songpa-gu, Seoul, Korea. Electronic address:
    Objective: Sensory organization test (SOT) is used to evaluate postural instability. We wanted to characterize the SOT findings in patients with acute vestibular neuritis (VN).

    Methods: Eighty-seven patients with VN were enrolled. Read More

    Clinical effects of submucosal middle turbinectomy for eosinophilic chronic rhinosinusitis.
    Auris Nasus Larynx 2017 Nov 24. Epub 2017 Nov 24.
    Department of Otolaryngology, Faculty of Medicine, Kagawa University, Kita-gun, Miki-cho, Ikenobe 1750-1, Kagawa 761-0793, Japan.
    Objective: The preservation or resection of the middle turbinate (MT) during endoscopic sinus surgery (ESS) currently remains a matter of debate. The present study aimed to investigate the effects of submucosal middle turbinectomy (SMT) in ESS for eosinophilic chronic rhinosinusitis (ECRS).

    Methods: The study included 38 ECRS patients (63 sides) who had undergone full-house ESS with SMT and 20 ECRS patients (40 sides) without SMT as a control group. Read More

    Antitumor miR-150-5p and miR-150-3p inhibit cancer cell aggressiveness by targeting SPOCK1 in head and neck squamous cell carcinoma.
    Auris Nasus Larynx 2017 Dec 9. Epub 2017 Dec 9.
    Department of Functional Genomics, Chiba University Graduate School of Medicine, Chiba, Japan. Electronic address:
    Objective: Our recent studies have revealed that both strands of pre-miRNAs, the guide strand and the passenger strand, are involved in cancer pathogenesis. Analyses of miRNA expression signatures by RNA sequencing in head and neck squamous cell carcinoma (HNSCC) showed that both of the strands of pre-miR-150 (miR-150-5p and miR-150-3p) were significantly downregulated, and that these miRNAs acted as antitumor miRNAs in HNSCC cells. The aim of this study was to identify oncogenic genes in HNSCC cells that were regulated by miR-150-5p and miR-150-3p. Read More

    Anti-mumps IgM antibody positive rate with sudden sensorineural hearing loss using second-generation enzyme immunoassay: A retrospective, multi-institutional investigation in Hokkaido, Japan.
    Auris Nasus Larynx 2017 Dec 7. Epub 2017 Dec 7.
    Department of Otolaryngology-Head & Neck Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, Hokkaido 060-8638, Japan.
    Objective: Although elevated anti-mumps IgM antibody levels were reported in 5.7%-7.2% of Japanese patients with sudden sensorineural hearing loss (SSNHL), there were several reports of false-positive cases, such as the continually IgM positive case and the IgM positive case in normal adults. Read More

    Diagnostic and treatment effects of sialendoscopy for patients with swelling of the parotid gland when sialoliths are undetected with computed tomography.
    Auris Nasus Larynx 2017 Dec 4. Epub 2017 Dec 4.
    Department of Otolaryngology, Tokyo Women's Medical University, 8-1, Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan.
    Between August 2009 and May 2016, 74 patients underwent sialoendoscopic surgery. 32 patients had parotid gland disease and 9 patients had intermittent swelling of the parotid gland and sialoliths were not detected with CT imaging. 4 patients were diagnosed with idiopathic Stensen's duct stenosis. Read More

    Factors influencing recurrent emergency department visits for epistaxis in the elderly.
    Auris Nasus Larynx 2017 Dec 2. Epub 2017 Dec 2.
    Sealy Center on Aging, Galveston, TX, United States; Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, United States.
    Objective: Our objective is to determine the risk factors associated with recurrent epistaxis requiring emergency department (ED) visits in the elderly.

    Methods: We used a 5% national sample of Medicare data from January 2012 through December 2013. Our cohort included patients with a new diagnosis of epistaxis in the ED, defined as no epistaxis in the prior 12 months. Read More

    Lymph node ratio as a prognostic factor for survival in patients with head and neck squamous cell carcinoma.
    Auris Nasus Larynx 2017 Dec 1. Epub 2017 Dec 1.
    Department of Otorhinolaryngology, Head and Neck Surgery, Yokohama City University, School of Medicine, Yokohama, Japan.
    Objective: The purpose of this study is to validate the concept of lymph node ratio (LNR) in head and neck squamous cell carcinoma (HNSCC).

    Methods: A total of 63 patients with HNSCC who underwent resection of the primary tumor combined with neck dissection in our institution were analyzed in this study. LNR was defined as the number of positive lymph nodes divided by the total number of lymph nodes excised. Read More

    Leaflets and continual educational offerings led to increased coverage rate of newborn hearing screening in Akita.
    Auris Nasus Larynx 2017 Nov 28. Epub 2017 Nov 28.
    Department of Otorhinolaryngology, Head & Neck Surgery, Akita University Graduate School of Medicine, Akita, Japan.
    Objective: Newborn hearing screening (NHS) has been actively performed in Japan since 2001. The NHS coverage rate has increased each year in Akita Prefecture. We analyzed the details of the NHS program and how the Akita leaflets and the many educational offerings about the importance of NHS led to the high NHS coverage rate. Read More

    An improved system for grading and treating tinnitus.
    Auris Nasus Larynx 2017 Nov 27. Epub 2017 Nov 27.
    Department of Otolaryngology, Head and Neck Surgery, Nagoya City University Medical School, Japan.
    Objective: Tinnitus is an auditory sensation that can cause discomfort or even pain. Because patients with tinnitus frequently have psychological problems, self-reporting of the severity of tinnitus is unreliable. We developed a new grading system and practical protocol for the systematic treatment of tinnitus that accounts for its severity, patients' psychological problems, and the frequency of catastrophic episodes. Read More

    The serum leptin level in non-obese patients with obstructive sleep apnea.
    Auris Nasus Larynx 2017 Nov 21. Epub 2017 Nov 21.
    Hacettepe University, Faculty of Medicine, Department of Otorhinolaryngology, 06100 Sıhhiye, Ankara, Turkey.
    Objective: This study aimed to determine the association between the severity of obstructive sleep apnea (OSA) and the serum leptin level in non-obese OSA patients.

    Methods: This prospective case-control study included non-obese OSA patients that presented with sleep-related disturbances and underwent polysomnography (PSG) between April 2015 and June 2016. The serum leptin level was measured and its relationship to PSG parameters was investigated. Read More

    Pediatric type 1 cartilage tympanoplasty outcomes: A comparison of short and long term hearing results.
    Auris Nasus Larynx 2017 Nov 17. Epub 2017 Nov 17.
    Ege University School of Medicine, Otolaryngology Department, 35100, Bornova, Izmir, Turkey. Electronic address:
    Objective: Tympanoplasty is a commonly used procedure in children as in adults. The purposes of this study were to evaluate and report the long term results of type 1 cartilage tympanoplasty in pediatric population. Short term and long term hearing outcomes were compared according to age and perforation location. Read More

    Language-specific strategy for programming hearing aids - A double-blind randomized controlled crossover study.
    Auris Nasus Larynx 2017 Nov 17. Epub 2017 Nov 17.
    Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
    Objective: Voice-aligned compression (VAC) is a method used in Oticon's hearing aids to provide more comfortable hearing without sacrificing speech discrimination. The complex, non-linear compression curve for the VAC strategy is designed based on the frequency profile of certain spoken Western languages. We hypothesized that hearing aids could be further customized for Japanese-speaking users by modifying the compression curve using the frequency profile of spoken Japanese. Read More

    Improving surgical results in complex nerve anatomy during implantation of selective upper airway stimulation.
    Auris Nasus Larynx 2017 Nov 15. Epub 2017 Nov 15.
    Department of Otorhinolaryngology, Head and Neck Surgery, Klinikum rechts der Isar, Munich, Germany.
    The following report presents a case of two late embedded hypoglossus branches during implantation of an upper airway stimulation device that caused a mixed activation of the tongue when included in the stimulation cuff. In the end, correct cuff placement could be achieved by careful examination of the hypoglossal nerve anatomy, precise nerve dissection, tongue motion analysis and intraoperative nerve monitoring. Read More

    Diagnostic criteria for Patulous Eustachian Tube: A proposal by the Japan Otological Society.
    Auris Nasus Larynx 2017 Nov 15. Epub 2017 Nov 15.
    Department of Otolaryngology - Head and Neck Surgery, Nagasaki University Institute of Biomedical Sciences, Nagasaki, Japan.
    Patulous Eustachian Tube (PET) is of increasing importance in otology. However, despite the abundance of diseases requiring a differential diagnosis from PET, such as superior semicircular canal dehiscence syndrome, perilymphatic fistula, acute low-tone sensorineural hearing loss, etc., there are currently no established diagnostic criteria for PET. Read More

    Reduction of olfactory sensitivity during normobaric hypoxia.
    Auris Nasus Larynx 2017 Nov 15. Epub 2017 Nov 15.
    Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Center, Johannes Gutenberg University, Mainz, Germany; Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig Maximilians University Munich, Germany.
    Objective: Acute mountain sickness (AMS) is caused by a low partial pressure of oxygen and may occur above 2500m. The aim of this research was to evaluate olfactory and gustatory abilities of healthy subjects during baseline conditions and after seven hours of normobaric hypoxia.

    Methods: Sixteen healthy subjects were assessed using the Sniffin' Sticks, as well as intensity and pleasantness ratings. Read More

    Frontal sinus revision rate after nasal polyposis surgery including frontal recess clearance and middle turbinectomy: A long-term analysis.
    Auris Nasus Larynx 2017 Nov 14. Epub 2017 Nov 14.
    ENT - Head and Neck Surgery Department, European Hospital Georges Pompidou, AP-HP, Paris, France; Faculty of Medicine Paris Descartes, University Paris V, Paris, France.
    Objective: To determine the frontal sinus revision rate after nasal polyposis (NP) surgery including frontal recess clearance (FRC) and middle turbinectomy (MT), to search for predictive factors and to analyse surgical management.

    Methods: Longitudinal analysis of 153 patients who consecutively underwent bilateral sphenoethmoidectomy with FRC and MT for NP with a minimum follow-up of 7 years. Decision of revision surgery was made in case of medically refractory chronic frontal sinusitis or frontal mucocele. Read More

    De novo head and neck cancer arising in solid organ transplantation recipients: The Asan Medical Center experience.
    Auris Nasus Larynx 2017 Nov 14. Epub 2017 Nov 14.
    Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. Electronic address:
    Objective: De novo cancers of head and neck area in solid organ transplantation recipients show standardized incidence ratio (SIR) of 3.8. Immunosuppression following transplantation is suggested to play as a crucial factor in pathogenesis of secondary malignancy. Read More

    Soft palate reconstruction after radionecrosis: Combined anterolateral thigh adipofascial and nasoseptal flaps.
    Auris Nasus Larynx 2017 Nov 13. Epub 2017 Nov 13.
    Washington University, Department of Otolaryngology-Head and Neck Surgery, Saint Louis, MO, United States.
    Although radiation-based treatment for nasopharyngeal cancer may achieve excellent long term oncologic results, late effects of therapy may lead to soft tissue radionecrosis and velopharyngeal insufficiency (VPI). Repair of these oro- and nasopharyngeal defects presents a complex reconstructive challenge. We present a case of a long-term survivor treated with chemoradiotherapy for nasopharyngeal cancer who developed progressive dysphagia, velopharyngeal insufficiency, and radionecrosis of the nasopharynx and soft palate, leading to tracheostomy and gastrostomy tube dependence. Read More

    Transcanal endoscopic ear surgery for perilymphatic fistula after electric acoustic stimulation.
    Auris Nasus Larynx 2017 Nov 6. Epub 2017 Nov 6.
    Department of Otolaryngology - Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-Cho, Kita-Ku, Okayama 700-8558, Japan.
    Transcanal endoscopic ear surgery (TEES) will become a very useful therapeutic option. A perilymphatic fistula (PLF) is defined as sudden sensorineural hearing loss and/or vertigo caused by leakage of the perilymph through a fistula from the oval window and/or round window. We report a case of PLF after electric acoustic stimulation (EAS), a kind of cochlear implant, successfully treated by TEES. Read More

    Influence of pneumococcal conjugate vaccines on acute otitis media in Japan.
    Auris Nasus Larynx 2017 Nov 1. Epub 2017 Nov 1.
    Department of Otolaryngology, Head and Neck Surgery, Graduate School of Biomedical & Health Sciences, Applied Life Sciences, Hiroshima University, Hiroshima, Japan.
    Objective: This study investigated: (i) changes in the incidence of acute otitis media (AOM) following introduction of public funding for free inoculation with 7- and 13-valent pneumococcal conjugate vaccines (PCV7 and PCV13, respectively) and (ii) changes in the rate of myringotomies for AOM (MyfA) in children 1year following the publication of the first edition of the clinical practice guidelines for the diagnosis and management of AOM in children in Japan.

    Methods: PCV7 was launched on the Japanese market in 2010 and gained public funding in 2011. PCV7 was replaced with PCV13 in November 2013. Read More

    Modified Z-palatoplasty with one-layer closure in one-stage multilevel surgery for severe obstructive sleep apnea.
    Auris Nasus Larynx 2017 Oct 25. Epub 2017 Oct 25.
    Sleep Center of Chang Gung Memorial Hospital, Chiayi, Taiwan; Division of Pulmonary and Critical Care Medicine, Chang Gung Memorial Hospital, Chiayi, Taiwan; Department of Nursing, Chang-Gung University of Science and technology, Chiayi, Taiwan.
    Objective: The meticulous two-layer closure is a step to complete the modified Z-palatoplasty, which has been reported to serve as an effective element in multilevel sleep surgery for patients with severe obstructive sleep apnea, especially with Friedman anatomical stages II and III diseases. A single layer closure-the suture closure as originally described in uvulopalatopharyngoplasty by Fujita et al., is an alternative of the two-layer closure, featured by simplicity while its efficacy has not been completely proved in patients with severe obstructive sleep apnea. Read More

    Factors affecting the effect of physical rehabilitation therapy for synkinesis as a sequela to facial nerve palsy.
    Auris Nasus Larynx 2017 Oct 31. Epub 2017 Oct 31.
    Department of Otolaryngology-Head & Neck Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Kita-Ku, N15W7, Sapporo 0608638, Hokkaido, Japan.
    Objective: To investigate factors affecting the effect of physical rehabilitation therapy for synkinesis as a sequela to facial nerve palsy.

    Methods: A total of 37 patients with peripheral facial nerve palsy in Teine-Keijinkai Hospital were enrolled in this study. All patients showed synkinesis at 6 months after the onset of facial nerve palsy and were instructed in physical rehabilitation by expert staff from their first visit. Read More

    Oncocytic carcinoma of the salivary glands: A Danish national study.
    Auris Nasus Larynx 2017 Oct 31. Epub 2017 Oct 31.
    Department of ORL - Head and Neck Surgery, Odense University Hospital, Denmark.
    Objectives: To present a Danish national series of oncocytic carcinoma (OC) patients, including data on treatment, recurrence and survival.

    Methods: From the national Danish database of salivary gland carcinomas, all patients diagnosed with OC from 1990 to 2005 were identified and data concerning demographics, tumor site, clinical stage and treatment profiles were extracted. A follow-up was carried out. Read More

    Detection of voice changes due to aspiration via acoustic voice analysis.
    Auris Nasus Larynx 2017 Oct 30. Epub 2017 Oct 30.
    Department of Otolaryngology-Head and Neck Surgery, Republic of Korea. Electronic address:
    Objective: Aspiration can occur during swallowing. The present study investigated the feasibility of identifying aspiration risk (AR) via acoustic voice parameters.

    Materials And Methods: In total, 165 patients scheduled for a videofluoroscopic swallowing study (VFSS) were included. Read More

    Cerebellar ataxia with neuropathy and vestibular areflexia syndrome (CANVAS).
    Auris Nasus Larynx 2017 Oct 28. Epub 2017 Oct 28.
    Department of Otolaryngology - Head and Neck Surgery, Kyoto Prefectural University of Medicine, Japan.
    Cerebellar ataxia with neuropathy and bilateral vestibular areflexia syndrome (CANVAS) is a novel ataxic disorder consisting of the triad of cerebellar impairment, bilateral vestibular hypofunction, and a somatosensory deficit. We report the first Japanese case of CANVAS. The patient is a 68-year-old Japanese male. Read More

    A rare case of bilateral vagus nerve schwanomatosis.
    Auris Nasus Larynx 2017 Oct 28. Epub 2017 Oct 28.
    Department of Otorhinolaryngology, National Hospital Organization Tokyo Medical Center, Tokyo, Japan. Electronic address:
    Schwanomatosis is the third most common form of neurofibromatosis. Schwanomatosis affecting the vagus nerve is particularly rare. In this report, we describe an extremely rare case bilateral vagus nerve schwanomatosis in a 45-year-old male patient. Read More

    A population-based comparison of European and North American sinonasal cancer survival.
    Auris Nasus Larynx 2017 Oct 19. Epub 2017 Oct 19.
    Department of Otolaryngology - Head and Neck Surgery, Rutgers New Jersey Medical School, Newark, New Jersey, USA; Center for Skull Base and Pituitary Surgery, Neurological Institute of New Jersey, Rutgers New Jersey Medical School, Newark, New Jersey, USA; Department of Neurological Surgery, Rutgers New Jersey Medical School, Newark, New Jersey, USA; Department of Ophthalmology and Visual Science, Rutgers New Jersey Medical School, Newark, New Jersey, USA. Electronic address:
    Objective: Sinonasal cancers (SNC) are rare, thus limiting previous prognostic studies on a multinational level. The aim of this study is to utilize two population-based datasets to compare prognoses for SNC between the United States (US) and Europe.

    Methods: The European Cancer Registry (EUROCARE) database and the United States National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) database were searched to identify survival of patients diagnosed with SNC between 1990 and 2007. Read More

    A high jugular bulb and poor development of perivestibular aqueductal air cells are not the cause of endolymphatic hydrops in patients with Ménière's disease.
    Auris Nasus Larynx 2017 Oct 19. Epub 2017 Oct 19.
    Department of Otorhinolaryngology - Head and Neck Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
    Objective: The presence of endolymphatic hydrops in the inner ear, which can be detected with gadolinium-enhanced magnetic resonance imaging (Gd-MRI), is widely recognized as the main pathological cause of Ménière's disease (MD). However, the precise mechanisms underlying the development of endolymphatic hydrops remains unclear. One hypothesis proposes a relationship between the presence of a high jugular bulb (HJB) and MD, which disrupts the vestibular aqueduct leading to the development of endolymphatic hydrops. Read More

    Correlation between computed tomography imaging and histopathology in pleomorphic adenoma of parotid gland.
    Auris Nasus Larynx 2017 Oct 18. Epub 2017 Oct 18.
    Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul, Republic of Korea; Sensory Organ Research Institute, Seoul National University Medical Research Center, Seoul National University Hospital, Seoul, Republic of Korea; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea; Clinical Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address:
    Objective: The purpose of this study was to correlate the CT imaging features and histopathological findings of pleomorphic adenomas (PA), and also try to identify its clinical significance.

    Methods: Totally 262 PAs in the parotid gland including 18 recurrent cases were retrospectively reviewed with preoperative CT and pathologic slides. Each pathologic slide was reviewed by two pathologists to calculate mean value of epithelial/mesenchymal component, and the results were correlated with features of CT scans. Read More

    Influence of Ginkgo Biloba extract (EGb 761) on expression of IL-1 Beta, IL-6, TNF-alfa, HSP-70, HSF-1 and COX-2 after noise exposure in the rat cochlea.
    Auris Nasus Larynx 2017 Oct 14. Epub 2017 Oct 14.
    Bezmialem Vakif University, Department of Otorhinolaryngology, Fatih, Istanbul, Turkey.
    Objective: The objective of this study was to investigate the influence of Ginkgo Biloba in early treatment of noise induced hearing loss on expression of IL-6, IL-1 Beta, TNF-alfa, HSP-70, HSF-1 and COX-2 in the rat cochlea.

    Methods: Thirty two female rats were randomly divided into four groups (Acoustic Trauma, Ginkgo Biloba, Acoustic Trauma+Ginkgo Biloba, Non Treatment). Auditory brainstem response (ABR) was applied in all the groups. Read More

    Outcomes of pediatric delayed facial palsy after head trauma.
    Auris Nasus Larynx 2017 Oct 12. Epub 2017 Oct 12.
    Department of Otolaryngology, Cangzhou Central Hospital, Cangzhou 061001, Hebei, PR China. Electronic address:
    Objective: To analyze clinical outcomes of delayed facial palsy after head trauma in the pediatric population.

    Methods: A total of 45 pediatric cases with delayed facial palsy after head trauma were conservatively or surgically treated in our hospital between January 2009 and January 2015, and they were followed up for one year after the corresponding treatment. The clinical data were collected and the outcomes of facial nerve were analyzed. Read More

    Facial nerve neuroma in the geniculate ganglion extending into the internal auditory canal: A case report.
    Auris Nasus Larynx 2017 Oct 5. Epub 2017 Oct 5.
    Department of Neurosurgery, Akita Graduate School of Medicine, 1-1-1, Hondo, Akita 010-8543, Japan.
    Facial nerve schwannoma is a very rare benign tumor representing less than 1% of intrapetrous lesions. Our patient is a forty-one year old female who has suffered from recurrent right facial palsy for the last six years. She was first misdiagnosed as having Bell's palsy and received corticosteroids which resulted in little improvement. Read More

    Electroneurography in the acute stage of facial palsy as a predictive factor for the development of facial synkinesis sequela.
    Auris Nasus Larynx 2017 Sep 28. Epub 2017 Sep 28.
    Department of Otolaryngology, University of Tokushima School of Medicine, Tokushima 770-8503, Japan.
    Objective: We investigated whether the value of ENoG is a predictive factor for the development of facial synkinesis in patients with facial palsy.

    Methods: The degree of oral-ocular synkinesis was evaluated quantitatively by an asymmetry of the interpalpebral space width during the mouth movement (% eye opening). Twenty healthy volunteers without a history of facial palsy (12 men and 8 women; 25-65 years old; mean age: 42. Read More

    Schwannoma of external auditory canal.
    Auris Nasus Larynx 2017 Sep 28. Epub 2017 Sep 28.
    Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Medical School & Chonnam National University Hwasun Hospital, Hwasun, Korea. Electronic address:
    Schwannomas of the external auditory canal are extremely rare and only a few cases have been reported in the literature. Herein, we report a case of schwannoma of the external ear canal in a 41-year male. Clinicians should consider the possibility that the schwannoma may originate in the external auditory canal mimicking other more frequently observed lesions. Read More

    Comparison of snoring sounds between natural and drug-induced sleep recorded using a smartphone.
    Auris Nasus Larynx 2017 Sep 27. Epub 2017 Sep 27.
    Department of Otorhinolaryngology, Sleep laboratory, Busan Saint Mary's Hospital, Busan, South Korea.
    Objectives: Snoring is an important clinical feature of obstructive sleep apnea (OSA), and recent studies suggest that the acoustic quality of snoring sounds is markedly different in drug-induced sleep compared with natural sleep. However, considering differences in sound recording methods and analysis parameters, further studies are required. This study explored whether acoustic analysis of drug-induced sleep is useful as a screening test that reflects the characteristics of natural sleep in snoring patients. Read More

    Endoscopic enucleation of large jaw cysts: Promising outcomes.
    Auris Nasus Larynx 2017 Sep 23. Epub 2017 Sep 23.
    Otolaryngology Department, Faculty of Medicine, Mansoura University, Egypt. Electronic address:
    Objective: To describe the endoscopic approach for management of large jaw cysts and assess the feasibility of endoscopic enucleation as well as analyze its outcome on a wide scale at Mansoura University Hospital MUH.

    Methods: This prospective cohort study was done on 23 consecutive cases presenting with different types of large jaw cysts in the period from January 2013 to July 2016 at ENT Department, Mansoura University Hospital. All patients, (16 maxillary & 7 mandibular) cysts, were managed endoscopically. Read More

    3D-constructive interference into steady state (3D-CISS) labyrinth signal alteration in patients with vestibular schwannoma.
    Auris Nasus Larynx 2017 Sep 22. Epub 2017 Sep 22.
    Department of Otorhinolaryngology and Head & Neck Surgery, Inselspital, University of Bern, Bern, Switzerland. Electronic address:
    Objective: To evaluate signal intensity of the inner ear using 3D-CISS imaging and correlated signal characteristics in patients with vestibular schwannoma to neuro-otological symptoms.

    Methods: Sixty patients with unilateral vestibular schwannoma were retrospectively reviewed. All patients had had initial and follow-up magnetic resonance imaging (MRI). Read More

    High-dose corticosteroids improve the prognosis of Bell's palsy compared with low-dose corticosteroids: A propensity score analysis.
    Auris Nasus Larynx 2017 Sep 22. Epub 2017 Sep 22.
    Department of Otolaryngology Head and Neck Surgery, Kurashiki Central Hospital, Miwa 1-1-1, Kurashiki, Okayama 710-8602, Japan.
    Objective: The aim of this study was to evaluate the effectiveness of high-dose corticosteroid (120mg prednisolone equivalent daily) in Bell's palsy compared with low-dose corticosteroid (60mg PSL equivalent).

    Methods: A single-center retrospective observational study was performed. We included adult Bell's palsy patients who were treated within 7days after disease onset. Read More

    Extraskeletal osteosarcoma in the parotid gland: A case report.
    Auris Nasus Larynx 2017 Sep 22. Epub 2017 Sep 22.
    Department of Anatomical Pathology, Hiroshima University Hospital, Hiroshima, Japan.
    Extraskeletal osteosarcoma is a very rare tumor and accounts for 4-5% of all osteosarcomas. We describe a 47-year-old Japanese man who presented with a right parotid tumor. The patient underwent total resection with postoperative radiotherapy; however, the tumor recurred in the lung, whereupon he underwent chemotherapy and partial lung resection. Read More

    Our experience with 500 patients with benign paroxysmal positional vertigo: Reexploring aetiology and reevaluating MRI investigation.
    Auris Nasus Larynx 2017 Sep 21. Epub 2017 Sep 21.
    Department of Otorhinolaryngology and Head and Neck Surgery, Beaumont Hospital and Blackrock Clinic, Dublin, Ireland.
    Objective: To explore the aetiology of and to evaluate the importance of MRI investigation on the posterior semicircular canal benign paroxysmal positional vertigo in an Irish population.

    Methods: A retrospective observational study of 500 patients with posterior semicircular canal benign paroxysmal positional vertigo, diagnosed and treated by the senior author over a 10-year period. Most patients underwent an MRI brain and inner ear, following the same scan protocol. Read More

    Management of tinnitus in children: Review of literature and effect of counseling.
    Auris Nasus Larynx 2017 Sep 21. Epub 2017 Sep 21.
    Department of Otorhinolaryngology - Head and Neck Surgery, Seoul National University Boramae Medical Center, Seoul National University College of Medicine, Seoul, South Korea. Electronic address:
    Objective: Tinnitus in children has not been studied sufficiently to date. And, there is no consensus regarding the management of tinnitus in children. Tinnitus counseling can be considered as the most basic tool among therapeutic options of tinnitus in children. Read More

    A case of adult congenital laryngeal cleft asymptomatic until hypopharynx cancer treatment.
    Auris Nasus Larynx 2017 Sep 21. Epub 2017 Sep 21.
    Otorhinolaryngology - Head and Neck Surgery, Osaka General Medical Center, Bandai-higashi 3-1-56, Sumiyoshi-ku, Osaka 558-8558, Japan.
    Laryngeal cleft is an anomaly of failed posterior closure of the larynx. Most cases are diagnosed and need treatment early in life due to respiratory and swallowing problems. We report an unusual case of a 66-year-old man with an asymptomatic laryngeal cleft until treatment for hypopharyngeal cancer. Read More

    Lamina papyracea position in patients with nasal polypi: A computed tomography analysis.
    Auris Nasus Larynx 2017 Sep 20. Epub 2017 Sep 20.
    Radio Diagnosis Department, Faculty of Medicine, Benha University, Egypt.
    Objective: This study aimed to describe the positions of the lamina papyracea (LP) in patients who had nasal polypi, by computed tomography (CT) analysis.

    Methods: Paranasal CT scans of patients diagnosed to have nasal polypi were included in the study. CT images were acquired with multiplanar reformates to obtain delicate details in coronal planes for all subjects. Read More

    Doppler ultrasonography can be useful to determine the etiology of idiopathic sudden sensorineural hearing loss.
    Auris Nasus Larynx 2017 Sep 20. Epub 2017 Sep 20.
    Acibadem University Hospital, Otorhinolaryngology Department Istanbul, Turkey.
    Objective: This study aims to evaluate clinical features of both carotid and vertebral arteries in the idiopathic sudden sensorineural hearing loss (ISSNHL) patients and healthy individuals to contribute additional knowledge on vascular compromise theory.

    Methods: This study was designed as a retrospective case control study in a tertiary referral center. 55 patients for ISSNHL and 35 healthy participants (70 ears) are involved to the study. Read More

    A targeted next-generation sequencing panel reveals novel mutations in Japanese patients with primary ciliary dyskinesia.
    Auris Nasus Larynx 2017 Sep 19. Epub 2017 Sep 19.
    Division of Personalized Medicine, Mie University Graduate School of Medicine, Tsu, Japan.
    Objective: Primary ciliary dyskinesia (PCD) is a rare genetic disorder caused by functional impairment of cilia throughout the body. The early diagnosis of PCD is important for the prevention of long-term sequelae; however, this is often challenging because of the phenotypic heterogeneity of PCD and difficulty in genetic analysis. The majority of PCD patients in Japan are not diagnosed properly. Read More

    Treatment outcomes of sialendoscopy for submandibular gland sialolithiasis: The minor axis of the sialolith is a regulative factor for the removal of sialoliths in the hilum of the submandibular gland using sialendoscopy alone.
    Auris Nasus Larynx 2017 Sep 18. Epub 2017 Sep 18.
    Department of Otolaryngology, Tokyo Women's Medical University, 8-1, Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan.
    Objective: To assess the general guidelines for the removal of sialoliths for submandibular gland sialolithiasis using sialendoscopy alone.

    Methods: We analyzed 61 sialoliths treated using sialendoscopy in 42 patients with submandibular gland sialolithiasis. We evaluated the submandibular gland sialoliths and divided each case based upon the location: the Wharton's duct or the hilum. Read More

    Tonsillectomy in adults: Analysis of indications and complications.
    Auris Nasus Larynx 2017 Sep 16. Epub 2017 Sep 16.
    Department of Anatomy and Histology, University of Zaragoza, Spain.
    Objective: Tonsillectomy is one of the surgical techniques most practiced by otolaryngologists, and despite being a relatively simple technique; it presents a considerable percentage of complications, such as postoperative bleeding. The aim of this study is to describe the surgical indications and most frequent complications, analyze whether surgical suture of the tonsillar pillars has an influence on bleeding, and study the data of hospital stay and its importance for the control of complications.

    Methods: A retrospective study of 326 patients who underwent a tonsillectomy in our Department of Otolaryngology from 2006 to 2014 was conducted. Read More

    Natural course of tonsillectomy pain: A prospective patient cohort study.
    Auris Nasus Larynx 2017 Sep 7. Epub 2017 Sep 7.
    Department of Otorhinolaryngology-Head and Neck Surgery, Hallym University Sacred Heart Hospital, Anyang, Republic of Korea. Electronic address:
    Objective: The aim of this study was to determine the natural course of pain after tonsillectomy.

    Methods: This study included 119 patients that underwent tonsillectomy between November 2013 and November 2015. After undergoing tonsillectomy, patients scored their pain using the visual analogue scale three times daily (morning, midday, and evening) for 2 weeks. Read More

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