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    3057 results match your criteria Auris Nasus Larynx [Journal]

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    Steroid pulse therapy transiently destroys the discriminative histological structure of tonsils in IgA nephropathy: Tonsillectomy should be performed before or just after steroid pulse therapy.
    Auris Nasus Larynx 2018 May 19. Epub 2018 May 19.
    Departmnet of Otolaryngology-Head and Neck Surgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan.
    Objective: Tonsillectomy combined with steroid-pulse therapy is a widely accepted method for the treatment of IgA nephropathy (IgAN) in Japan. However, the indication of tonsillectomy for IgAN is still controversial, and the timing of tonsillectomy is not clearly defined for the protocol of this therapy. Based on the results of a randomized control trial in Japan, the Evidence-Based Clinical Practice Guidelines for IgA nephropathy 2014 (edited in Japan) recommended tonsillectomy combined with steroid-pulse therapy for Grade C1. Read More

    Operative technique for benign submandibular gland mass without identifying the mandibular branch of the facial nerve.
    Auris Nasus Larynx 2018 May 19. Epub 2018 May 19.
    Department of Otorhinolaryngology, Head and Neck Surgery, Osaka Medical College, Takatsuki, Japan.
    Objective: The marginal mandibular branch of the facial nerve must be protected during surgery for benign diseases of submandibular gland. Methods for protecting the marginal mandibular branch include the nerve identification method and the non-identification method.

    Methods: We performed submandibular gland surgery in 138 patients with benign submandibular gland diseases using the non-identification method to preserve the marginal mandibular branch. Read More

    Fracture probability assessed using FRAX in elderly women with benign paroxysmal positional vertigo.
    Auris Nasus Larynx 2018 May 18. Epub 2018 May 18.
    Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, 65 Tsurumai-Cho, Showa-ku, Nagoya 466-8550, Japan.
    Objective: Patients with benign paroxysmal positional vertigo (BPPV) can have vitamin D deficiency, which is a cause of abnormal bone turnover. Several studies have established a relationship between osteoporosis and BPPV. The World Health Organization Fracture Risk Assessment Tool, widely known as FRAX (http://www. Read More

    Successful treatment switch from lenvatinib to sorafenib in a patient with radioactive iodine-refractory differentiated thyroid cancer intolerant to lenvatinib due to severe proteinuria.
    Auris Nasus Larynx 2018 May 17. Epub 2018 May 17.
    Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Graduate School of Medicine, 7-5-1, Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan; Kobe University Hospital Cancer Center, 7-5-2, Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan. Electronic address:
    Sorafenib and lenvatinib showed efficacy for patients with radioactive iodine (RAI)-refractory differentiated thyroid cancer (DTC) in pivotal phase 3 clinical trials. Although the efficacy of lenvatinib in patients who received previous treatment with multi-target kinase inhibitors (m-TKIs), including sorafenib, was reported, the efficacy of sorafenib in patients who previously received lenvatinib remains unknown. A 75-year-old woman diagnosed as RAI-refractory poorly differentiated carcinoma with multiple lung metastases and started treatment with lenvatinib. Read More

    A rare cause of primary hyperparathyroidism: Parathyroid lipoadenoma.
    Auris Nasus Larynx 2018 May 16. Epub 2018 May 16.
    Department of Surgery, Ankara Numune Training and Research Hospital, Ankara, Turkey.
    Objective: The main cause of primary hyperparathyroidism is a single parathyroid adenoma. Parathyroid lipoadenomas contain abundance of fat cells. Because of these histological features, they can mimic normal parathyroid tissue at the histopathologic examination and radiological imaging could be difficult to localize lipoadenomas. Read More

    Transoral videolaryngoscopic surgery for papillary carcinoma arising in lingual thyroid.
    Auris Nasus Larynx 2018 May 15. Epub 2018 May 15.
    Department of Otolaryngology-Head & Neck Surgery, Kobe University Hospital, Kobe, Japan.
    Carcinoma arising in lingual thyroid is an extremely rare entity accounting for only 1% of all reported ectopic thyroids. Here, we report a case of carcinoma arising in lingual thyroid, which has been successfully managed by transoral resection and bilateral neck dissections. A lingual mass 4-cm in diameter with calcification was incidentally detected by computed tomography at medical check-up. Read More

    Stapes surgery preserving the superstructure of stapes (Takagi's stapedotomy) in otosclerosis: A retrospective study of 24 consecutive cases.
    Auris Nasus Larynx 2018 May 14. Epub 2018 May 14.
    Department of Otolaryngology, Kurashiki Central Hospital, 1-1-1 Miwa, Kurashiki City, Okayama Prefecture, 710-8602, Japan. Electronic address:
    Objective: The aim of this study was to evaluate the hearing outcomes and complications of stapedotomy in which the stapes superstructure was preserved (Takagi's stapedotomy). In this surgical approach, the lenticular process of the incus rather is removed, than the superstructure of the stapes.

    Methods: A single-center retrospective observational study was performed. Read More

    Middle-ear disease in children with cleft palate.
    Auris Nasus Larynx 2018 May 12. Epub 2018 May 12.
    Boston Children's Hospital, Department of Otolaryngology & Communication Enhancement, 333 Longwood Avenue, 3rd Floor, Boston, MA 02115, United States. Electronic address:
    Objective: The objective of this review is to summarize all aspects of middle ear diseases in children with cleft palate (CP).

    Methods: PubMed, Scopus, The Cumulative Index to Nursing and Allied Health Literature (CINAHL) and The Cochrane Library were searched for English-language randomized control trials (RCTs), meta-analyses, systematic reviews and observational studies published through 31st July 2017.

    Results: Epidemiology and pathogenesis of middle ear diseases in children with cleft palate have been discussed in this review. Read More

    A novel fluoroscopic method for multidimensional evaluation of swallowing function.
    Auris Nasus Larynx 2018 May 9. Epub 2018 May 9.
    Department of Orthopedic Biomaterial Science, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
    Objective: Dynamic videofluoroscopic swallow study (VFSS) is used to investigate swallowing movements. However, it requires prolonged radiation exposure and mainly provides qualitative information. Herein, we present a multi-dimensional method for analyzing swallowing based on a pulsed, low-dose fluoroscopy technique that uses serial-shot images and evaluates the size, position, and temporal profile of the bolus to obtain a more comprehensive and realistic analysis of swallowing movements. Read More

    Pyoderma gangrenosum on the nose.
    Auris Nasus Larynx 2018 May 9. Epub 2018 May 9.
    Department of Otolaryngology, Japanese Red Cross Saitama Hospital, Shintoshin 1-5, Chuo-ku, Saitama-shi, Saitama, 330-8533, Japan.
    Pyoderma gangrenosum is a rare ulcerative condition associated with various systemic diseases. Lesions on the lower extremities and the trunk are common, but lesions on the nose are rare. Here we report a case of pyoderma gangrenosum on the nose. Read More

    A retrospective study of treatment for curative synchronous double primary cancers of the head and neck and the esophagus.
    Auris Nasus Larynx 2018 May 8. Epub 2018 May 8.
    Department of Otorhinolaryngology-Head and Neck Surgery, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami, Sagamihara, Kanagawa, 252-0374, Japan.
    Objective: Curative synchronous double primary cancers of the head and neck and the esophagus (CSC-HE) are frequently detected, but a standard treatment remains to be established. We studied the clinical course to explore appropriate treatment strategies.

    Methods: We retrospectively studied consecutive 33 patients who had CSC-HE. Read More

    The possible effect of human menopausal gonadotropin on the audio-vestibular system.
    Auris Nasus Larynx 2018 May 7. Epub 2018 May 7.
    Obstetrics and Gynecology Department, Minia University Hospital, Minia, Egypt.
    Objective: Human menopausal gonadotropin (HMG) is one of the commonest drugs used for ovarian stimulation with no reports on the audio-vestibular system. This study aims to examine HMG on the hearing profile of patients planning intracytoplasmic sperm injection (ICSI).

    Methods: This prospective study was conducted from June 2016 to June 2017 in a tertiary referral hospital. Read More

    Comparison of VEMPS, VHIT and caloric test outcomes after vestibular neurectomy in Menière's disease.
    Auris Nasus Larynx 2018 May 7. Epub 2018 May 7.
    Department of Surgical Sciences, Otolaryngology Unit, University of Turin, Turin, Italy.
    Objective: Selective unilateral vestibular neurectomy (VN) is considered a reliable surgical treatment in case of recurrent vertigo in Menière's disease (MD) because of hearing preservation and a minimally invasive posterior fossa retrosigmoid approach. The present study aimed to assess the quality of life and the long-term vestibular function in patients submitted to yearly follow-up after VN because of intractable MD.

    Methods: Retrospective series of 15 MD patients undergoing retrosigmoid VN for recurrent vertigo. Read More

    The protective effect of adrenocorticotropic hormone treatment against noise-induced hearing loss.
    Auris Nasus Larynx 2018 May 7. Epub 2018 May 7.
    Baskent University Medical Faculty, Otorhinolaryngology Department, Ankara, Turkey.
    Objective: NIHL is a common problem, and steroids are the most effective treatment option. In this study, we aimed to evaluate the protective effects of the synthetic adrenocorticotropic hormone (ACTH) analogues, which induce endogenous steroid secretion, against noise-induced hearing loss (NIHL) and to compare their effectiveness with that of steroid treatment.

    Methods: Twenty-four male Sprague-Dawley albino rats were divided into four subgroups as follows: group 1 (n=6) control, group 2 (n=6) saline, group 3 (n=6) dexamethasone (2mg/kg/day intramuscularly [IM]), group 4 (n=6) ACTH analogue (0,4mg/kg/day IM), respectively. Read More

    Postoperative hypoparathyroidism after total thyroidectomy for thyroid cancer.
    Auris Nasus Larynx 2018 May 7. Epub 2018 May 7.
    Department of Otolaryngology-Head and Neck Surgery, Kobe University Graduate School of Medicine, 7-5-1, Kusunoki-cho, Chuo-Ku, Kobe, Hyogo 650-0017, Japan.
    Objectives: Postoperative hypoparathyroidism (HPT) is one of the most common complications in total thyroidectomy for thyroid carcinoma. Parathyroid glands (PTGs) are at risk of being damaged during total thyroidectomy and central neck dissection mainly due to inadvertent removal, interruption of the blood supply or hematoma formation. The purpose of this study was to evaluate the efficacy of our surgical procedure to preserve for parathyroid function retrospectively and to clarify the risk factors of HPT after total thyroidectomy for thyroid cancer. Read More

    Characteristics of tinnitus found in anemia patients and analysis of population-based survey.
    Auris Nasus Larynx 2018 Apr 26. Epub 2018 Apr 26.
    Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Boramae Medical Center, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address:
    Objective: This study analyzed the characteristics of tinnitus identified in anemia patients with cohort- and population-based studies in a single institute and suggests a management algorithm.

    Methods: Fifty patients who were treated for anemia and referred for tinnitus treatment were included in a single institute retrospective study. Characteristics of tinnitus were investigated in a correlation analysis with demographic and audiologic parameters. Read More

    The palatal septal cartilage implantation for snoring and obstructive sleep apnea.
    Auris Nasus Larynx 2018 Apr 26. Epub 2018 Apr 26.
    Department of Otorhinolaryngology-Head and Neck Surgery, Sleep Center, Linkou-Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan, ROC; Department of Sleep Medicine, Royal Infirmary Edinburgh, UK. Electronic address:
    Objective: Patients with snoring and obstructive sleep apnea frequently have nasal and palatal obstruction. The objective of this study was to investigate the safety and feasibility of a palatal septal cartilage implant (SCI) for snoring and obstructive sleep apnea.

    Methods: This was a preliminary study of 10 consecutive patients who were enrolled retrospectively from electronic charts. Read More

    Overcoming wound complications in head and neck salvage surgery.
    Auris Nasus Larynx 2018 Apr 21. Epub 2018 Apr 21.
    Coordinator of The International Head and Neck Scientific Group, Italy. Electronic address:
    Background: Loco-regional treatment failure after radiotherapy with or without chemotherapy and/or prior surgery represents a significant portion of head and neck cancer patients. Due to a wide array of biological interactions, these patients have a significantly increased risk of complications related to wound healing.

    Methods: Review of the current literature was performed for wound healing pathophysiology, head and neck salvage surgery, and wound therapy. Read More

    Predictive value of the Hyodo score in endoscopic evaluation of aspiration during swallowing.
    Auris Nasus Larynx 2018 Apr 20. Epub 2018 Apr 20.
    Department of Otorhinolaryngology - Head and Neck Surgery, Yokohama City University, School of Medicine, Yokohama, Japan; Department of Biology and Function in Head and Neck, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
    Objective: The Hyodo scoring system during the endoscopic procedure has been proposed as a new tool for evaluating oral intake feasibility. However, the effectiveness of the information obtained from this procedure in predicting aspiration is not fully elucidated. The aim of this study was to assess the significance of clinical factors, including Hyodo scores, for predicting the risk of aspiration. Read More

    The influence of marital status on survival for patients aged 65 years and younger with oral cavity cancer.
    Auris Nasus Larynx 2018 Apr 20. Epub 2018 Apr 20.
    Department of Otolaryngology, Head, and Neck Surgery, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; School of Medicine, National Defense Medical Center, Taipei, Taiwan; Department of Otolaryngology, Head, and Neck Surgery, Tri-Service General Hospital, Taipei, Taiwan; Institute of Hospital and Health Care Administration, National Yang-Ming University. Electronic address:
    Objective: In Taiwan, the median age of diagnosis for oral cavity cancer is 51 year old, which is about 10 years earlier than that in Western countries. A recent study assessing the effect of marriage on outcomes for elderly oral cavity cancer patients (≥66 years old) showed that marriage was associated with better survival. However, little is known about the prognostic significance of marital status in oral cavity cancer patients aged 65 years and younger. Read More

    Pneumolabyrinth, intracochlear and vestibular fluid loss after cochlear implantation.
    Auris Nasus Larynx 2018 Apr 18. Epub 2018 Apr 18.
    Department of Otorhinolaryngology, Shinshu University School of Medicine, Matsumoto, Japan; Department of Hearing Implant Sciences , Shinshu University School of Medicine , Matsumoto , Japan.
    The present case was a 38-year-old male who presented with progressive hearing loss, resulting in profound bilateral hearing loss. He had a past history of childhood medulloblastoma, which was treated with posterior fossa craniotomy and radiotherapy. A ventriculoperitoneal (VP) shunt was put in place to manage the hydrocephalus. Read More

    Management of laryngeal cleft in mechanically ventilated children with severe comorbidities.
    Auris Nasus Larynx 2018 Apr 16. Epub 2018 Apr 16.
    Department of Otolaryngology, The University of Tokyo, Tokyo, Japan.
    Laryngeal clefts are rare congenital malformations of the posterior part of the larynx. The severities are correlated with the downward extension of the cleft and can involve numerous clinical symptoms including dysphagia and respiratory distress. As significant comorbidities may be present, individual treatments depend on the child's general condition and type of cleft involved. Read More

    Comparison of functional outcomes after total thyroidectomy and completion thyroidectomy: Hypoparathyroidism and postoperative complications.
    Auris Nasus Larynx 2018 Apr 7. Epub 2018 Apr 7.
    Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul, Republic of Korea. Electronic address:
    Objective: This study aimed to investigate differences in functional outcomes of postoperative complications and hypoparathyroidism between patients who underwent completion thyroidectomy (CT) after thyroid lobectomy or total thyroidectomy (TT) as an initial treatment.

    Materials And Methods: We retrospectively analyzed the differences of functional outcomes after completion thyroidectomy and total thyroidectomy without lymph node dissection. We reviewed the medical records of 396 patients who underwent CT or TT for thyroid disease at Korea University Guro Hospital from March 2002 to August 2016. Read More

    Facial nerve palsy and laryngospasm as a complication of local anaesthesia during adenotonsillectomy.
    Auris Nasus Larynx 2018 Apr 5. Epub 2018 Apr 5.
    Department of Otorhinolaryngology, Nysa District Hospital, Poland.
    Tonsil surgeries are the most frequently performed surgical procedures in ENT departments. We would like to present the case of a 5-year-old patient who suffered from unilateral peripheral facial nerve palsy and laryngeal spasm following adenotonsillectomy. Paresis was observed immediately after the transfer of the patient to the postoperative room. Read More

    The safety and risk factors of revision adenoidectomy in children and adolescents: A nationwide retrospective population-based cohort study.
    Auris Nasus Larynx 2018 Mar 30. Epub 2018 Mar 30.
    Department of Otolaryngology Head & Neck Surgery, Taipei Veterans General Hospital, Taipei, Taiwan; Department of Otolaryngology, National Yang-Ming University School of Medicine, Taipei, Taiwan. Electronic address:
    Objective: To investigate the safety of adenoidectomy and risk factors of re-adenoidectomy, and intend to provide evidence-based information to clinicians for further consideration.

    Methods And Materials: This study was based on data obtained from Taiwan's National Health Insurance Research Database from the period 2002-2011. We utilized that data from the hospitalization group and collected information regarding those individuals who accepted adenoidectomy with or without tonsillectomy and post-adenoidectomy bleeding. Read More

    Trend in otolaryngological surgeries in an era of super-aging: Descriptive statistics using a Japanese inpatient database.
    Auris Nasus Larynx 2018 Mar 27. Epub 2018 Mar 27.
    Department of Otolaryngology, Head and Neck Surgery, Faculty of Medicine, The University of Tokyo, Tokyo, 1130033, Japan.
    Objective: To reveal the age distribution and capture the longitudinal trend in otolaryngological surgeries performed in Japan, where society is rapidly aging.

    Methods: Using the Diagnosis Procedure Combination database, we extracted data on patients who were hospitalized and underwent any type of otolaryngological surgery in departments of otolaryngology or head and neck surgery from fiscal year 2007 to fiscal year 2013. Type of surgery, patient's age, and fiscal year were compared. Read More

    Cochlear implant function in a patient with Jervell and Lange-Nielsen syndrome after defibrillation by countershock.
    Auris Nasus Larynx 2018 Aug 24;45(4):890-893. Epub 2018 Mar 24.
    Department of Otolaryngology-Head & Neck Surgery, Iwate Medical University, 19-1, Uchimaru, Morioka, Iwate 020-8505, Japan.
    Jervell and Lange-Nielsen syndrome (JLNS), a rare autosomal recessive congenital QT prolongation syndrome, is characterized by cardiac arrhythmias, syncopal episodes, and profound deafness. A cochlear implant (CI) for patients with JLNS is expected to result in hearing improvement. Sometimes, defibrillation is required if a patient experiences lethal arrhythmia. Read More

    Analysis of chemosensory function in patients with chronic Eustachian tube dysfunction prior to and after balloon dilatation.
    Auris Nasus Larynx 2018 Mar 20. Epub 2018 Mar 20.
    Department of Otorhinolaryngology-Head and Neck Surgery, University Hospital Marburg, Philipps-Universität Marburg, Germany; Department of Otorhinolaryngology-Head and Neck Surgery, Chemnitz Hospital GmbH, Chemnitz, Germany.
    Objective: Eustachian tube dysfunction (ETD) affects approximately 1% of adults in the general population. Non treated Eustachian tube dysfunction can result in chronic middle ear diseases, which have been shown to significantly affect taste sensitivity. A promising treatment is balloon dilatation of the Eustachian tube. Read More

    Multicenter phase I/II study of chemoradiotherapy with high-dose CDDP for head and neck squamous cell carcinoma in Japan.
    Auris Nasus Larynx 2018 Mar 19. Epub 2018 Mar 19.
    Departments of Otolaryngology Head and Neck Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
    Objective: Recent data indicated that concurrent chemoradiotherapy (CCRT) using high dose cisplatin (CDDP) is the most useful treatment for advanced head and neck squamous cell carcinoma (SCC). Regarding the dose of CDDP, 100mg/m is most recommended in Western countries. However, in terms of a balance of efficacy and adverse events, appropriate dose of cytotoxic drugs such as CDDP may be different among the different ethnic groups. Read More

    Sound energy absorbance characteristics of cartilage grafts used in type 1 tympanoplasty.
    Auris Nasus Larynx 2018 Mar 15. Epub 2018 Mar 15.
    Dokuz Eylul University School of Medicine, Department of Otorhinolaryngology, Izmir, Turkey. Electronic address:
    Objective: The purpose of this prospective case-control study is to evaluate the sound energy absorbance characteristics of cartilage grafts in patients, who have undergone type 1 cartilage tympanoplasty.

    Methods: Thirty-four operated ears of 32 patients and 70 ears of 35 control subjects were included. Differences of pure-tone audiometry thresholds and wideband ambient-pressure absorbance ratios with respect to the graft material, graft thickness, cartilage surface area ratio and elapsed time after surgery were analyzed. Read More

    Clinical features of nasal and sinonasal inverted papilloma associated with malignancy.
    Auris Nasus Larynx 2018 Mar 13. Epub 2018 Mar 13.
    Department of Otolaryngology, Head and Neck Surgery, Kurashiki Central Hosipital, 1-1-1 Miwa, Kurashiki, Okayama 710-8602, Japan.
    Objective: Nasal and sinonasal inverted papilloma (IP) are rare benign tumors and have the potential to exhibit malignancy in approximately 10% of cases. This study aimed to analyze the clinical features of IP associated with malignancy. Furthermore, we reviewed our therapeutic strategy and the clinical course of malignant IP. Read More

    Effects of nasal septum perforation repair on nasal airflow: An analysis using computational fluid dynamics on preoperative and postoperative three-dimensional models.
    Auris Nasus Larynx 2018 Mar 13. Epub 2018 Mar 13.
    Department of Otolaryngology, Saitama Medical Center, Saitama Medical University, 1981 Kamoda, Kawagoe-shi, Saitama, 380-8550, Japan.
    Objective: The purpose of this research is to examine the changes in nasal airflow dynamics before and after the nasal perforation repair.

    Methods: Three dimensional (3D) models of the nasal cavity before and after septal perforation repair was reconstructed using preoperative and postoperative computed tomography (CT) images of a patient. The numerical simulation was carried out using ANSYS CFX V15. Read More

    Relation between globus pharyngeus and OSA in patients examined simultaneously by PSG and pH monitor: A cross sectional study.
    Auris Nasus Larynx 2018 Mar 12. Epub 2018 Mar 12.
    Department of Otolaryngology, Nagoya City University, Nagoya, Japan.
    Objective: This was a first cross-sectional single-center study to research the relation between globus pharyngeus, OSA and GERD. Since previous clinical studies have demonstrated a relationship between globus phayrngeus and GERD, however, no reported study on the relation between globus pharyngeus, sleep disorders including OSA, and GERD.

    Methods: Seventeen patients underwent general and otorhinolaryngological examinations and responded to several questionnaires (ESS, PSQI, HADS, and Globus pharyngeus VAS score) at their first visit, and underwent a gastroesophageal test for 24-h pH monitoring and in-laboratory PSG one to two months later. Read More

    Home particle repositioning maneuver to prevent the recurrence of posterior canal BPPV.
    Auris Nasus Larynx 2018 Mar 8. Epub 2018 Mar 8.
    Faculty of Medicine, Mansoura University, Egypt.
    Objective: To check the value of home particle repositioning maneuver in the prevention of the recurrence of posterior canal benign paroxysmal positional vertigo (pc-BPPV).

    Methods: In this study, patients diagnosed as unilateral posterior canal BPPV were selected following an accurate evaluation using video goggle VNG system. All patients were managed by particle repositioning maneuver (PRM). Read More

    Music enjoyment with cochlear implantation.
    Auris Nasus Larynx 2018 Mar 5. Epub 2018 Mar 5.
    Columbia University Cochlear Implant Center Department of Otolaryngology-Head and Neck Surgery, New York, NY, United States; Division of Otology, Neurotology and Skull Base Surgery, Department of Otolaryngology, Head & Neck Surgery, Columbia University College of Physicians & Surgeons, New York, NY, United States. Electronic address:
    Since the advent of cochlear implant (CI) surgery in the 1960s, there have been remarkable technological and surgical advances enabling excellent speech perception in quiet with many CI users able to use the telephone. However, many CI users struggle with music perception, particularly with the pitch-based and melodic elements of music. Yet remarkably, despite poor music perception, many CI users enjoy listening to music based on self-report questionnaires, and prospective studies have suggested a disassociation between music perception and enjoyment. Read More

    Reliability and validity of the Japanese version of the Glasgow Edinburgh Throat Scale (GETS-J): Use for a symptom scale of globus sensation.
    Auris Nasus Larynx 2018 Mar 6. Epub 2018 Mar 6.
    Department of Otolaryngology Head and Neck Surgery, Niigata University Graduate School of Medical and Dental Sciences, Japan.
    Objective: Globus sensation, a feeling of lump or something stuck in the throat, could be caused by structural, functional, and psychogenic diseases. Due to a possible multifactorial nature of the disease, neither diagnosing test battery nor standard treatment for globus sensation has been established. Therefore, a questionnaire to accurately identify globus patients and evaluate the severity of the disease is desired. Read More

    Innate immunity gene expression by epithelial cells of upper respiratory tract in children with adenoid hypertrophy.
    Auris Nasus Larynx 2018 Aug 2;45(4):753-759. Epub 2018 Mar 2.
    Pirogov Russian National Research Medical University, Moscow, Russian Federation; Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russian Federation; I.Mechnikov Research Institute of Vaccines and Sera, Moscow, Russian Federation. Electronic address:
    Background: A major role of the innate immunity in the defence of mucosal tissue is well established. However, a balance between the main components of the immunity such as toll-like receptors (TLRs) and defensins in the pathology of upper respiratory tract in children has not been addressed yet. Our aim was to investigate the gene expression of some TLRs as well as alpha and beta-defensins in children suffered from adenoid hyperthrophy in comparison with healthy children. Read More

    Environmental factors associated with allergic rhinitis symptoms in Japanese university students: A cross-sectional study.
    Auris Nasus Larynx 2018 Feb 20. Epub 2018 Feb 20.
    Division for Health Service Promotion, The University of Tokyo, Tokyo, Japan.
    Objective: Numerous studies have reported that various environmental factors during early life are key determinants for developing allergic disease. Herein, we aimed to investigate the impact of environmental factors on allergic rhinitis.

    Methods: This cross-sectional study was conducted in a single university in Japan (from April to June, in 2015 and 2016). Read More

    Treatment of pediatric esthesioneuroblastoma with smell preservation.
    Auris Nasus Larynx 2018 Feb 20. Epub 2018 Feb 20.
    Clinic of Otolaryngology, Head and Neck Surgery, Department of Translational Surgery and Medicine, University of Florence, Italy.
    Olfactory neuroblastoma is a rare malignant tumor of neuroectodermal origin and represents the most common cancer of the nasal cavity in pediatric age. The gold standard of treatment consists of en bloc resection, numerous studies have shown as the endoscopic approaches permit good control of the disease improving the quality of life after the treatment. Herein we describe the case of a 13-year-old patient referred to our outpatient clinic with a polypoid multi-lobed lesion occupying the left nasal cavity and imaging that confirmed a left-sided nasal mass without cribriform plate involvement (Kadish B). Read More

    Usefulness of reconstructed 3D images for cochlear implantation in a case with a facial nerve anomaly.
    Auris Nasus Larynx 2018 Feb 14. Epub 2018 Feb 14.
    Department of Otolaryngology, Jichi Medical University, Tochigi, Japan; Department of Pediatric Otolaryngology, Jichi Medical University, Tochigi Pediatric Medical Center, Tochigi, Japan. Electronic address:
    Facial nerve anomalies are a potential problem in patients with cochleovestibular malformations. A case of cochlear implant (CI) surgery in the presence of intra-temporalbone facial nerve bifurcation is presented. During the first surgery, the facial nerve bifurcation obscured the promontory and round window. Read More

    Cribriform plate width is highly variable within and between subjects.
    Auris Nasus Larynx 2018 Feb 13. Epub 2018 Feb 13.
    Department of Otolaryngology - Head & Neck Surgery, Virginia Commonwealth University School of Medicine, Richmond, VA, United States; Department of Physiology and Biophysics, Virginia Commonwealth University School of Medicine, Richmond, VA, United States.
    Objective: All successful endonasal surgery, including functional endoscopic sinus surgery (FESS), depends on knowledge of both anatomy and the specific variations that can occur between and within patients. Familiarity with these structures is a critical component in preventing complications from these procedures, and failure to understand subtle variation can have disastrous results. The aim of this study was to characterize the anatomical variations (if any) of the cribriform plate using a large cadaveric sample set. Read More

    Survival in patients with submandibular gland carcinoma - Results of a multi-institutional retrospective study.
    Auris Nasus Larynx 2018 Feb 7. Epub 2018 Feb 7.
    Department of Otolaryngology - Head & Neck Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
    Objective: Clinical studies demonstrating the prognostic factors in submandibular gland carcinoma are limited because the tumor is relatively rare. The aim of this study was to identify clinical outcomes and prognostic factors in submandibular gland carcinoma.

    Methods: The study included 65 patients with submandibular gland carcinoma who underwent initial surgical treatment at the Kyoto University and its affiliated hospitals. Read More

    A questionnaire to assess olfactory rehabilitation for laryngectomized patients (Provox voice prosthesis users) in Japan.
    Auris Nasus Larynx 2018 Feb 7. Epub 2018 Feb 7.
    Tokyo Voice Center, Sanno Hospital, International University of Health and Welfare, 8-10-16 Akasaka, Minato-ku Tokyo 107-0052, Japan. Electronic address:
    Objective: We used a questionnaire to investigate olfactory function and the present state of olfactory rehabilitation for laryngectomized patients in Japan.

    Methods: This study was conducted using a questionnaire survey. We mailed questionnaires to 190 members of a Japanese laryngectomized patient group (the nonprofit organization YOUSAY-KAI). Read More

    The gray scale value of ear tissues undergoing volume-rendering high-resolution cone-beam computed tomography.
    Auris Nasus Larynx 2018 Feb 7. Epub 2018 Feb 7.
    Department of Otolaryngology, Kochi University, Medical School, Nankoku, Kochi, Japan.
    Objective: When the thresholds for VR reconstruction from multi-slice CT images are changed, problems develop when assessing pathologies in the absence of standardized thresholds. The advantages of CBCT include lower radiation exposure compared with other techniques and better visualization of small ear structures. However, a disadvantage is that the scanner provides unstandardized gray scale values, thus not CT numbers (Hounsfield units, HU). Read More

    Factors affecting the outcome of adenoidectomy in children treated for chronic otitis media with effusion.
    Auris Nasus Larynx 2018 Feb 6. Epub 2018 Feb 6.
    2nd Department of Otorhinolaryngology - Head and Neck Surgery, Aristotle University of Thessaloniki, Papageorgiou Hospital, Periferiaki Odos Efkarpia, 56403 Thessaloniki, Greece. Electronic address:
    Objective: The aim of this cohort was to determine potential risk factors, concerning the effectiveness of adenoidectomy in the treatment of chronic otitis media with effusion in children.

    Methods: Ninety six children with chronic otitis media with effusion treated with adenoidectomy were enrolled in this study. A thorough medical history was taken, including family history of otologic disease, parental smoking habits and breast feeding history. Read More

    Topical therapy for refractory rhinosinusitis caused by methicillin-resistant Staphylococcus aureus: First report in a prospective series.
    Auris Nasus Larynx 2018 Feb 6. Epub 2018 Feb 6.
    Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, United States.
    Objective: The incidence of refractory chronic rhinosinusitis (CRS) associated with methicillin-resistant Staphylococcus aureus (MRSA) is rising and remains a therapeutic challenge. The goal of this study is to demonstrate the efficacy of a non-invasive topical therapy against MRSA in these patients.

    Methods: Seventeen patients with refractory CRS caused by MRSA were treated with a topical therapy protocol. Read More

    Combined transoral-transhyoid endoscopic approach for hypopharyngeal cancer.
    Auris Nasus Larynx 2018 Feb 2. Epub 2018 Feb 2.
    Department of Otolaryngology, Japanese Red Cross Wakayama Medical Center, Wakayama, Japan.
    Endoscopic transoral surgery for hypopharyngeal cancer is an effective treatment option to avoid invasive open surgery or chemoradiation. Here we describe the case of a 66-year-old patient with cT2N0M0 pyriform sinus cancer whom we treated using a transoral-transhyoid endoscopic approach. Using this approach, a transhyoid route was created in addition to the transoral route and used to extirpate the tumor. Read More

    Instrumental head impulse test changes after intratympanic gentamicin for unilateral definite Ménière's disease: A systematic review and meta-analysis.
    Auris Nasus Larynx 2018 Feb 2. Epub 2018 Feb 2.
    Department of Otorhinolaryngology, S. João Hospital Centre, Alameda Prof. Hernâni Monteiro, Porto, Portugal; Department of Surgery and Physiology/Otorhinolaryngology, Faculty of Medicine, University of Porto, Alameda Prof. Hernâni Monteiro, Porto, Portugal; Center for Health Technology and Services Research (CINTESIS), Faculty of Medicine, University of Porto, Alameda Prof. Hernâni Monteiro, Porto, Portugal.
    Objective: To estimate how much could intratympanic gentamicin (ITG) interfere with the vestibular-ocular reflex (VOR) parameters on instrumental head impulse test (HIT), either with scleral search coil or video head impulse test and, eventually, foresee the control of vertigo crisis in unilateral intractable Ménière's disease (MD).

    Methods: A literature search was conducted in PubMed, Scopus, Web of Science and Cochrane search engines. The search terms used were "vestibular ocular reflex", "head impulse test", "gentamicin," and "Meniere's disease". Read More

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