3,382 results match your criteria Auris Nasus Larynx [Journal]


Endoscopic removal of a fish bone foreign body in the hypopharynx with the modified Killian's method.

Auris Nasus Larynx 2020 Jul 9. Epub 2020 Jul 9.

Department of Otolaryngology, Fukushima Medical University, 1 Hikarigaoka, Fukushima 960-1295, Japan. Electronic address:

Observing the entire circumference of the hypopharynx is usually difficult because most of the area is anatomically closed in the resting state. The modified Killian's method, consisting of a combination of the modified Killian position, head torsion, and the Valsalva maneuver, is a recently proposed procedure to improve the endoscopic view of the hypopharynx. A fish bone, which was invisible under regular endoscopy but was identified by CT, was successfully observed and removed under the modified Killian's method in a 71-year-old female. Read More

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http://dx.doi.org/10.1016/j.anl.2020.06.010DOI Listing

Intratympanic steroid injection for sudden sensorineural hearing loss: Impact of injection interval on therapeutic efficacy.

Auris Nasus Larynx 2020 Jul 7. Epub 2020 Jul 7.

Department of Otorhinolaryngology-Head and Neck Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. Electronic address:

Objective: To compare the effect of injection time intervals of intratympanic (IT) dexamethasone (DEX) in patients with idiopathic sudden sensorineural hearing loss (ISSNHL).

Methods: Seventy-five adults with ISSNHL were grouped into four groups according to the IT DEX interval. In addition to concurrent oral steroid medication for two weeks, patients received IT DEX injections every 1, 2, 3, and four days, respectively. Read More

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http://dx.doi.org/10.1016/j.anl.2020.06.009DOI Listing

The impact of middle ear aeration on surgical outcome after intact canal wall tympanoplasty for cholesteatoma.

Auris Nasus Larynx 2020 Jul 6. Epub 2020 Jul 6.

Department of Otorhinolaryngology, The Jikei University School of Medicine, 3-25-8 Nishi-Shimbashi, Minato-Ku, Tokyo 105-8461, Japan.

Objective: The aeration status of the middle ear is presumed to be one of the factors affecting the outcome in acquired cholesteatoma. The present study investigated the impact of postoperative middle ear aeration on hearing and recurrence after intact canal wall tympanoplasty.

Methods: We conducted a retrospective chart review of 127 pars flaccida cholesteatoma patients who underwent primary intact canal wall tympanoplasty at a tertiary academic medical center. Read More

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http://dx.doi.org/10.1016/j.anl.2020.06.006DOI Listing

Robotic thyroid surgery.

Authors:
Kyung Tae

Auris Nasus Larynx 2020 Jul 4. Epub 2020 Jul 4.

Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Hanyang University, 222 Wangsimni-ro, Seongdong-gu, Seoul 04763, Republic of Korea. Electronic address:

Various remote access robotic thyroidectomy techniques have been developed using the da Vinci® surgical system (Intuitive Surgical Inc., Sunnyvale, CA) to hide or avoid neck scarring and overcome the limitations of endoscopic thyroidectomy. Among those used today are the gasless transaxillary approach, the bilateral axillo-breast approach (BABA), the gasless postauricular facelift approach, and the transoral approach. Read More

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http://dx.doi.org/10.1016/j.anl.2020.06.007DOI Listing

The COVID-Box for tracheostomy: Additional complexity and unanswered questions.

Auris Nasus Larynx 2020 Jul 1. Epub 2020 Jul 1.

Senior Clinical Lecturer in Anaesthesia, Lancaster Medical School, Faculty of Health and Medicine, Lancaster University Lancaster, UK.

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http://dx.doi.org/10.1016/j.anl.2020.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330581PMC

Challenges in topical therapy of chronic rhinosinusitis: The case of nasal drops application - A systematic review.

Auris Nasus Larynx 2020 Jun 30. Epub 2020 Jun 30.

Department of Otorhinolaryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, University of Bern, CH-3010 Bern, Switzerland; Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Basel, CH-4051, Basel, Switzerland. Electronic address:

Objective: Chronic rhinosinusitis (CRS) is a common health issue associated with a significant life quality impairment. Intranasal glucocorticoid is the treatment of choice both as initial therapy as well as after surgery. In contrast to nasal spray, liquid glucocorticoids in form of nasal drops have the advantage of reaching the middle and upper meatus. Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.026DOI Listing

The effects of behind-the-ear and off-the-ear sound processors on speech understanding performance in cochlear implant users.

Auris Nasus Larynx 2020 Jun 23. Epub 2020 Jun 23.

Marmara University School of Medicine, Audiology Department, Address: Fevzi Çakmak Mah. Mimar Sinan Cd. No:10, Pendik, Istanbul 34899, Turkey.

Objective: The first aim of this study was to compare speech understanding performance in adult cochlear implant users using behind-the-ear and off-the-ear sound processors in quiet and noise. Second, the impact of sound processor microphone location on speech understanding performance was compared.

Methods: Participants were tested with both types of sound processors in the free field with warble tones, and speech discrimination scores in quiet were obtained. Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.025DOI Listing

Relationships of opacification in the nasal sinuses, rhinosinusitis, and antiresorptive agent-related osteonecrosis of the jaw.

Auris Nasus Larynx 2020 Jun 23. Epub 2020 Jun 23.

Department of Otolaryngology, Head and Neck Surgery, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka, 181-8611 Tokyo, Japan.

Objective: Bone turnover suppression agents are widely used for prophylaxis of bone metastases from cancer and osteoporosis; the occurrence of their side effect, antiresorptive agent-related osteonecrosis of the jaw (ARONJ), has been increasing. We investigated the relationships between opacification in the nasal sinuses, rhinosinusitis, and ARONJ based on data obtained from oral surgeons.

Methods: We examined 132 patients who had been clinically diagnosed with ARONJ based on clinical observations; all patients had undergone treatment at the Departments of Otorhinolaryngology and Oral Surgery. Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.013DOI Listing

Periostin in middle ear mucosa according to eosinophilic otitis media severity: Middle ear pathology-based treatment.

Auris Nasus Larynx 2020 Jun 23. Epub 2020 Jun 23.

Department of Otolaryngology, Jichi Medical University Saitama Medical Center, 1-847 Amanuma, Saitama 330-8503, Japan.

Objective: Eosinophilic otitis media (EOM) is an intractable disorder associated with bronchial asthma and chronic rhinosinusitis with nasal polyposis. Periostin is an extracellular matrix protein secreted by fibroblasts in response to interleukin (IL)-4 and/or IL-13 and is a known marker for eosinophilic disorders. We assessed serum periostin levels and expression of periostin in the middle ear mucosa according to three grade of EOM severity (grade1 to 3). Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.014DOI Listing

Comparison of biodegradable synthetic polyurethane foam versus Gelfoam packing in cartilage graft myringoplasty procedures.

Authors:
Zhengcai Lou

Auris Nasus Larynx 2020 Jun 22. Epub 2020 Jun 22.

Zhengcai Lou MD Department of Otorhinolaryngology, affiliated Yiwu Hospital of Wenzhou medical university (Yiwu central hospital), Yiwu city 322000, Zhejiang provice, China. Electronic address:

Objective: To compare cartilage graft rates and graft morphologies when biodegradable Synthetic Polyurethane Foam (BSPF) and Gelfoam are used to pack the EAC after cartilage graft myringoplasty.

Methods: Eighty-two patients with chronic perforations underwent endoscopic myringoplasty and were randomized to receive Gelfoam or BSPF packing of the middle ear and EAC.The groups were compared with respect to the pre- and postoperative air-bone gap (ABG), graft integrity, graft epithelialization, graft lateralization, and exudate. Read More

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http://dx.doi.org/10.1016/j.anl.2020.06.002DOI Listing

Pulsatile tinnitus caused by pneumocephalus after Janneta surgery.

Auris Nasus Larynx 2020 Jun 22. Epub 2020 Jun 22.

Sen-En Rifu Otological Surgery Center, Miyagi, Japan.

Pulsatile tinnitus of nonvascular origin is rare. We herein present a case of pulsatile tinnitus complicated with Jannetta surgery due to a communication created between the drilled mastoid cells and epidural space. She was successfully cured by otological surgery where the mastoid tip was packed with bone cement. Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.024DOI Listing

ENT manifestation in COVID-19 patients.

Auris Nasus Larynx 2020 Jun 15. Epub 2020 Jun 15.

Assistant professor of Otorhinolaryngology, Head and Neck Surgery, Otorhinolaryngology-Head and Neck Surgery Department, Faculty of Medicine, Zagazig University, Egypt.

Objective: to detect, analyze and discuss the different ear nose throat (ENT) manifestations those were reported in COVID19 positive patients in the reviewed and published literatures.

Methods: We performed a search in the PubMed databases, Web of Science, LILACS, MEDLINE, SciELO, and Cochrane Library using the keywords; COVID-19, Novel coronavirus, corona, 2019-nCoV, SARS-CoV-2, ENT, ear, nose, throat, otorhinolaryngology, ORL, pharynx, ORL, smell, larynx, different ENT related symptoms. We reviewed published and peer reviewed studies that reported the ENT manifestations in COVID-19 laboratory-confirmed positive patients. Read More

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http://dx.doi.org/10.1016/j.anl.2020.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294298PMC

Risk of internal carotid injury due to peritonsillar abscess drainage.

Auris Nasus Larynx 2020 Jun 21. Epub 2020 Jun 21.

Gulhane Medical School, Department of Otolaryngology, Head and Neck Surgery, Ankara, Turkey.

Objective: Peritonsillar abscess (PTA) is one of the most commonly seen ear nose and throat (ENT) emergencies. The most catastrophic complication that may occur due to surgical treatment of PTA is injury of internal carotid artery. The aim of this study is to determine distance and angle between PTA with ICA; and to prevent possible complications. Read More

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http://dx.doi.org/10.1016/j.anl.2020.06.001DOI Listing

Letter to "Medial lingual lymph node metastasis in carcinoma of the tongue".

Auris Nasus Larynx 2020 Jun 21. Epub 2020 Jun 21.

Unit of Radiation Oncology, University of Brescia, ASST Spedali Civili of Brescia, Brescia, Italy.

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http://dx.doi.org/10.1016/j.anl.2020.05.023DOI Listing

Clinical practice guidelines for the diagnosis and management of acute otitis media in children-2018 update.

Auris Nasus Larynx 2020 Jun 20. Epub 2020 Jun 20.

Department of Microbiology and Infectious Diseases, Nara Medical University, 840 Shijo-cho, Kashihara-shi, Nara 634-8521, Japan.

Objective: "Clinical Practice Guidelines for the Diagnosis and Management of Acute Otitis Media in Children-2018 update (2018 Guidelines)" aim to provide appropriate recommendations about the diagnosis and management of children with acute otitis media (AOM), including recurrent acute otitis media (recurrent AOM), in children under 15 years of age. These evidence-based recommendations were created with the consensus of the subcommittee members, taking into consideration unique characteristics of bacteriology and antimicrobial susceptibilities of AOM pathogens in Japan, as well as global advances in vaccines.

Methods: The subcommittee re-evaluated key clinical issues based on SCOPE (a master plan of the guidelines) and created clinical questions (CQ) about the diagnosis and management of AOM patients. Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.019DOI Listing

Differences in hearing levels between siblings with hearing loss caused by GJB2 mutations.

Auris Nasus Larynx 2020 Jun 15. Epub 2020 Jun 15.

Division of Hearing and Balance Research, National Institute of Sensory Organs, National Hospital Organization Tokyo Medical Center, 2-5-1 Higashigaoka, Meguro-ku, Tokyo 152-8902, Japan; Medical Genetics Center, National Hospital Organization Tokyo Medical Center, 2-5-1 Higashigaoka, Meguro, Tokyo 152-8902, Japan. Electronic address:

Objective: Hearing loss caused by GJB2 mutations is inherited in an autosomal recessive manner (DFNB1); thus siblings of an affected child have a 25% chance of also being affected. Hearing loss among subsequent siblings carrying the same GJB2 mutation is a concern for parents and a frequent topic of enquiry during genetic counseling. Evidence exists for genotype-phenotype correlations of GJB2 mutations; however, no analysis of differences in hearing among siblings, in whom the common genetic background may decrease variation, has been reported. Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.008DOI Listing

The diagnostic value of detecting sudden smell loss among asymptomatic COVID-19 patients in early stage: The possible early sign of COVID-19.

Auris Nasus Larynx 2020 Jun 9. Epub 2020 Jun 9.

Department of Otolaryngology-Head and Neck Surgery, St. Vincent's hospital, College of Medicine, The Catholic University of Korea, Republic of Korea. Electronic address:

Importance: The newly emerged coronavirus disease 19 (COVID-19), is threatening the world. Olfactory or gustatory dysfunction is reported as one of the symptoms worldwide. As reported so far, different clinical features have been reported according to outbreak sites and gender; most of the patients, who complained of anosmia or hyposmia, were Europeans. Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282761PMC

Review of practical recommendations for otolaryngologists and head and neck surgeons during the COVID-19 pandemic.

Auris Nasus Larynx 2020 Jun 6. Epub 2020 Jun 6.

Department and Clinic of Otolaryngology, Head and Neck Surgery, Medical University in Wroclaw, Borowska 213 Street, 50556 Wroclaw, Poland.

Introduction: Otolaryngologists are at very high risk of COVID-19 infection while performing examination or surgery. Strict guidelines for these specialists have not already been provided, while currently available recommendations could presumably change in course of COVID-19 pandemic as the new data increases.

Objectives: This study aimed to synthesize evidence concerning otolaryngology during COVID-19 pandemic. Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275141PMC

Surgical management in a severe OSA patient diagnosed with Stickler syndrome.

Auris Nasus Larynx 2020 Jun 11. Epub 2020 Jun 11.

Department of Otorhinolaryngology, Head & Neck Surgery, School of Medicine, Kyung Hee University, Seoul, Republic of Korea. Electronic address:

Stickler syndrome is a genetic disorder of connective tissue. One of the major symptoms associated with this disorder is an oro-facial malformation, which may cause a submucous cleft or a complete cleft of the hard palate. A 32-year-old man diagnosed with Stickler syndrome and a submucosal cleft palate (SMCP) visited our hospital with a chief complaint of excessive daytime sleepiness. Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.016DOI Listing

Detailed MR imaging assessment of endolymphatic hydrops in patients with SLC26A4 mutations.

Auris Nasus Larynx 2020 Jun 11. Epub 2020 Jun 11.

Department of Otolaryngology, Shinshu University School of Medicine, 3-1-1, Asahi, Matsumoto City, 390-8621, Japan. Electronic address:

Objective: Mutations in SLC26A4 represent the second most common mutations in deafness patients. The majority of patients with SLC26A4 mutations have a large vestibular aqueduct (LVA). Recently, some reports showed the presence of endolymphatic hydrops (ELH) in patients with LVA on the basis of high-resolution enhanced 3T-MRI. Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.018DOI Listing

Orbital complications of infected mucocele in the paranasal sinuses.

Auris Nasus Larynx 2020 Jun 11. Epub 2020 Jun 11.

Department of Otolaryngology-Head & Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan.

Objective: Infected mucocele of the paranasal sinuses can induce orbital infection, including orbital subperiosteal abscess, which may lead to life-threatening intracranial complications. Effective diagnosis is important, and treatment should be aggressive. This paper presents our experiences in endoscopic surgical management of orbital complications secondary to infected paranasal sinus mucoceles. Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.012DOI Listing

Postoperative pain after tonsillectomy - the value of standardized analgesic treatment protocols.

Auris Nasus Larynx 2020 Jun 11. Epub 2020 Jun 11.

Department of Anesthesiology and Intensive Care Medicine, University Hospital of Cologne, Cologne, Germany.

Objective: To alleviate pain after tonsillectomy (TE) with escalating gradual treatment protocols in a prospective trial.

Materials & Methods: Following TE, 83 consecutive adult patients were treated with two different four-staged escalating analgesic protocols. Metamizole served as basic medication in protocol 1 (PT1; n = 44), whereas with protocol 2 (PT2; n = 39) ibuprofen was applied as baseline analgesic. Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.011DOI Listing

"Gas" laryngopharyngeal reflux cause unexplained chronic cough.

Auris Nasus Larynx 2020 Jun 11. Epub 2020 Jun 11.

Esophageal & Lung Institute, Allegheny Health Network, 4815 Liberty Avenue, Mellon Pavilion, Suite 158, Pittsburgh PA 15224, USA. Electronic address:

Hypopharyngeal multichannel intraluminal impedance (HMII) that can measure laryngopharyngeal reflux (LPR) events has supported the causal relationship between chronic cough (CC) and LPR containing liquid. However the role of "gas" LPR associated with CC has been poorly understood. We present two cases of patients with CC who had negative LPR containing liquid but had multiple episodes of "gas" LPR on HMII. Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.015DOI Listing

Feather foreign body caused periparotid and peritonsillar abscess in a 9-month-old girl.

Auris Nasus Larynx 2020 Jun 11. Epub 2020 Jun 11.

Department of Anaesthesiology and intensive care, University Hospital Centre Split, Split, Croatia; University of Split, School of Medicine, Soltanska 2, Split, Croatia.

Migratory foreign body appeared to be bird feather, caused peritonsillar and periparotid abscess in a nine-month-old infant. Patient presented painful, tender and fluctuating red neck mass on the left neck region II, and refusal of oral intake, with no fever. Azithromycin was introduced four days before presentation for suspected urinary tract infection. Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.021DOI Listing

Factors related to the satisfaction level of elderly hearing-impaired individuals with cochlear implants.

Auris Nasus Larynx 2020 Jun 10. Epub 2020 Jun 10.

Department of Otorhinolaryngology, Jikei University School of Medicine.

Objective: This study investigated factors related to the satisfaction level of cochlear implants for the elderly.

Methods: A survey was conducted by sending an anonymous self-reported questionnaire to medical facilities specializing in cochlear implantation throughout Japan and members of cochlear implant self-help groups aged 65 years and older. The subjects were divided into two age-based groups (under 75 and 75 years and older) to analyze the usage of cochlear implants. Read More

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http://dx.doi.org/10.1016/j.anl.2020.04.010DOI Listing

A study of 30 odors panel smell identification test, smell detection threshold and University of Pennsylvania Smell Identification Test (UPSIT) in Thailand.

Auris Nasus Larynx 2020 Jun 10. Epub 2020 Jun 10.

Department of Otorhinolaryngology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand. Electronic address:

Objectives: This study aims to evaluate the application of the University of Pennsylvania Smell Identification Test (UPSIT) in Thailand, as well as to conduct an odor detection threshold test using phenyl ethyl alcohol and a 30-odor smell identification test.

Methods: This study was conducted from May 2019 to March 2020. We included healthy volunteers without any olfactory complaints. Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.017DOI Listing

The influence of a noisy environment on hearing impairment and tinnitus: The hearing outcomes of 50-year-old male Japan ground self-defense force personnel.

Auris Nasus Larynx 2020 Jun 8. Epub 2020 Jun 8.

Department of Otolaryngology-Head and Neck Surgery, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan.

Objectives: Hearing loss is one of the biggest health problems in the world and occupational noise-induced hearing loss is recognized as the most common work-related illness. However, many factors that result in hearing loss make it difficult to define the specific factor that induces noise-induced hearing loss. To access the exact effect of occupational noise exposure on hearing, we conducted a cross-sectional cohort study of the relationship between noise exposure and hearing impairment in 50-year-old male Japanese Self-Defense Force (JSDF) personnel who work in a noisy environment. Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.010DOI Listing

A new variant of posterior canal-benign paroxysmal positional vertigo-canalolithiasis.

Auris Nasus Larynx 2020 Jun 7. Epub 2020 Jun 7.

Department of Otolaryngology-Head and Neck Surgery, Nagasaki Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan.

Objective: The characteristics of typical posterior canal-benign paroxysmal positional vertigo-canalolithiasis (P-BPPV-Can) are well known. We found 10 patients with a new variant of P-BPPV-Can: Reverse (Rev)-P-BPPV-Can. The characteristics and pathophysiology of Rev-P-BPPV-Can are discussed. Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.001DOI Listing

Surgical outcomes of simultaneous cochlear implantation with subtotal petrosectomy.

Auris Nasus Larynx 2020 Jun 6. Epub 2020 Jun 6.

Department of Otorhinolaryngology, Head and Neck Surgery, Chungnam National University, College of Medicine, South Korea. Electronic address:

Objective: To evaluate the surgical outcomes of simultaneous cochlear implantation (CI) with subtotal petrosectomy (SP).

Methods: Medical records of thirty-one patients (31 ears) who underwent simultaneous CI with SP in two tertiary referral centers for management of profound hearing loss secondary to chronic suppurative otitis media, cholesteatoma, previous open cavity, temporal bone fracture, and temporal bone irradiation were retrospectively analyzed. Pre and postoperative speech performances and related complications requiring surgical correction were evaluated. Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.009DOI Listing

Zygomatic root abscess: A rare entity not to be forgotten!

Auris Nasus Larynx 2020 Jun 5. Epub 2020 Jun 5.

Department of Otorhinolaryngology, The National University of Malaysia, Malaysia. Electronic address:

Zygomatic root abscess is a rare extracranial extratemporal complication of otitis media. To the best of our knowledge, there are only a few scattered cases of zygomatic root abscesses reported in the literature. We present an unusual case of a zygomatic root abscess in a 24 years old adult. Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.007DOI Listing

Endoscopy-assisted transoral resection of a parapharyngeal space schwannoma without mandibular dissection.

Auris Nasus Larynx 2020 Jun 5. Epub 2020 Jun 5.

Department of Otorhinolaryngology, Sapporo Medical University School of Medicine, Minami 1-jo Nishi 16-chome, Chuo-ku, Sapporo, Hokkaido, 060-0061, Japan. Electronic address:

Of the schwannomas that arise from the parapharyngeal space, those in the high cervical region are particularly invasive, requiring mandibular dissection. Because these tumors are benign, however, excessive surgical invasion and postoperative neurological complications should be avoided. Postoperative dropout symptoms may be avoided by intracapsular extraction, including nerve integrity monitoring (NIM) and narrow-band imaging (NBI). Read More

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http://dx.doi.org/10.1016/j.anl.2020.04.012DOI Listing

Overall survival and PD-L1 expression in patients with recurrent or metastatic head and neck cancer treated with nivolumab.

Auris Nasus Larynx 2020 Jun 4. Epub 2020 Jun 4.

Department of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Tokyo, Japan.

Objective: Our facility measures programmed cell death ligand 1 (PD-L1) expression in all patients before administering nivolumab. The aim of the present study is to clarify the association between overall survival (OS) and PD-L1 expression.

Patients And Methods: Subjects in this study were 52 patients with R/M-HNC cancer (45 men, 7 women) administered nivolumab in our facility between June 1, 2017 and January 31, 2019. Read More

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http://dx.doi.org/10.1016/j.anl.2020.02.018DOI Listing

Wideband acoustic immitance - Absorbance measurements in ears after stapes surgery.

Auris Nasus Larynx 2020 Jun 4. Epub 2020 Jun 4.

Department of Otorhinolaryngology Head and Neck Surgery, Medical University of Warsaw, ul. Banacha 1a, 02-097 Warszawa, Poland.

Objectives: The study aimed to thoroughly assess absorbance in ears after stapes surgery (stapedotomy/stapedectomy) and how stapes surgery affects wideband acoustic immittance (WAI) metrics.

Methods: Eighty-three otosclerotic ears were analyzed pre- and postoperatively. The analysis comprised: air-bone gap (ABG) and WAI which included absorbance measurements, resonance frequency assessment, low frequency tympanometry and metrics derived from these measures. Read More

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http://dx.doi.org/10.1016/j.anl.2020.04.011DOI Listing

Resection of a desmoid-type fibromatosis with a CTNNB1 p.S45P mutation using a cervico-thoracic approach: A case report and literature review.

Auris Nasus Larynx 2020 Jun 3. Epub 2020 Jun 3.

Department of Otolaryngology-Head and Neck Surgery, Asahikawa Medical University, Midorigaoka-Higashi 2-1-1-1, Asahikawa 078-8510, Japan.

Desmoid-type fibromatosis (DF) is a rare, locally infiltrative, and fibroblastic proliferative disease. DF usually arises from abdominal fascial tissue, but in rare cases, it can occur in extra-abdominal areas. A 73-year-old Japanese male complained of a painless, left anterior neck mass of 3-month duration. Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.004DOI Listing

Facial nerve course in the temporal bone: Anatomical relationship between the tympanic and mastoid portions for safe ear surgery.

Auris Nasus Larynx 2020 May 28. Epub 2020 May 28.

Department of Otolaryngology - Head & Neck Surgery, Osaka Medical College, Takatsuki, Japan.

Objective: Avoidance of iatrogenic injury to the facial nerve is crucial during ear surgery. The anatomical relationship between the tympanic portion of the facial canal (FC) and the mastoid portion of the facial nerve was analyzed using multi-slice computed tomography (CT) scans to avoid iatrogenic facial nerve injury.

Methods: In total, 364 ears of 351 patients who underwent CT scans were enrolled. Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.002DOI Listing

Fibrous dysplasia limited to an ossicle.

Auris Nasus Larynx 2020 May 27. Epub 2020 May 27.

Beckman Laser Institute Korea, College of Medicine, Dankook University, Cheonan, South Korea; Department of Otolaryngology-Head & Neck Surgery, College of Medicine, Dankook University Cheonan, South Korea. Electronic address:

Fibrous dysplasia is an unusual pathologic condition caused by abnormal bone metabolism. Temporal bone involvement is often seen, but it is uncommon to find fibrous dysplasia limited to the middle ear, especially originating in and confined to a single ossicle. Here we report a case of osteofibrous dysplasia limited exclusively to an ossicle (malleus) causing gradual conductive hearing loss, which recovered after eventual complete removal of the dysplastic area. Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.005DOI Listing

Therapeutic effect of Nivolumab for advanced / recurrent temporal bone squamous cell carcinoma.

Auris Nasus Larynx 2020 May 20. Epub 2020 May 20.

Department Otolaryngology Head and Neck Surgery, Kyushu University, 3-1-1 Maidashi, Fukuoka, Japan.

Objective: The immune checkpoint inhibitor Nivolumab was approved for the treatment of platinum-refractory head and neck squamous cell carcinoma (SCC), expanding the treatment options for recurrent or advanced head and neck SCC. However, since temporal bone squamous cell carcinoma (TB-SCC) is very rare cancer, the effectiveness of Nivolumab remains unclear. We investigated the effects of Nivolumab for TB-SCC. Read More

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http://dx.doi.org/10.1016/j.anl.2020.03.011DOI Listing

Barrier device prototype for open tracheotomy during COVID-19 pandemic.

Auris Nasus Larynx 2020 May 8. Epub 2020 May 8.

Department of Head and Neck Surgery, Walter Cantidio University Hospital of Universidade Federal do Ceara Medical School, Fortaleza, Ceara, Brazil.

Objective: To present a low-cost prototype for a barrier enclosure device which can be used during open surgeries such as tracheotomy.

Methods: We provide detailed description of a novel device called COVID-Box, developed by The Surgical Airway Team for COVID-19 Pandemic, a temporary task force formed by Walter Cantídio University Hospital. Safety guidelines for performing tracheotomies in COVID-19 patients are also stated. Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205665PMC

Overall survival and PD-L1 expression in patients with recurrent or metastatic head and neck cancer treated with nivolumab.

Auris Nasus Larynx 2020 May 19. Epub 2020 May 19.

Department of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.

Objective: Our facility measures programmed cell death ligand 1 (PD-L1) expression in all patients before administering nivolumab. The aim of the present study is to clarify the association between overall survival (OS) and PD-L1 expression.

Patients And Methods: Subjects in this study were 52 patients with R/M-HNC cancer (45 men, 7 women) administered nivolumab in our facility between June 1, 2017 and January 31, 2019. Read More

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http://dx.doi.org/10.1016/j.anl.2020.04.001DOI Listing

The impact of preoperative screening system on head and neck cancer surgery during the COVID-19 pandemic: Recommendations from the nationwide survey in Japan.

Auris Nasus Larynx 2020 May 16. Epub 2020 May 16.

Department of Head and Neck Surgery, Miyagi Cancer Center, Natori, Miyagi, Japan.

Objective: the pandemic of coronavirus disease 2019 (COVID-19), hospitals worldwide are at risk of nosocomial infection. Preoperative identification of COVID-19 in patients who are scheduled to be admitted to the hospital is essential to preventing the collapse of medical facility. In Japan, the preoperative observation and screening tests with the RT-PCR testing for the new coronavirus (SARS-CoV-2) and chest CT scan are recommended for head and neck cancer surgery during the COVID-19 pandemic. Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229909PMC

Trends in complications after functional endoscopic sinus surgery in Japan: A comparison with a previous study (2007-2013vs. 2013-2017).

Auris Nasus Larynx 2020 May 14. Epub 2020 May 14.

Department of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

Objective: Functional endoscopic sinus surgery (FESS) for chronic rhinosinusitis is considered safe and is widely performed. Techniques and devices for this type of surgery have recently been updated. The purpose of this study was to describe the proportions of complications after FESS (2013-2017) and to compare the results with those from our previous study (2007-2013). Read More

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http://dx.doi.org/10.1016/j.anl.2020.04.003DOI Listing

Resection of carcinoma of the external auditory canal in a patient with a high jugular bulb using temporal craniotomy.

Auris Nasus Larynx 2020 May 10. Epub 2020 May 10.

Department of Head and Neck Surgery, National Cancer Center Hospital, 5-1-1 Tsukiji, chuo, Tokyo 104-0045, Japan.

External auditory canal (EAC) carcinoma is a rare and unusual malignancy. The complex anatomy and relationship between the tumor and surrounding tissues in a limited space render it difficult to attain safe resection margins during surgery. A high jugular bulb (HJB) is one such anatomical variation that has important surgical implications that complicate the surgical procedure for EAC carcinoma. Read More

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http://dx.doi.org/10.1016/j.anl.2020.03.010DOI Listing

Long-term moderate noise exposure enhances the medial olivocochlear reflex.

Auris Nasus Larynx 2020 May 10. Epub 2020 May 10.

ENT Institute, Eye & ENT Hospital of Fudan University, Fenyang Road 83, Shanghai 200031, PR China; NHC Hearing Medicine Key Laboratory (Fudan University), Shanghai, PR China. Electronic address:

Objective: To investigate the effects of long-term moderate noise on hearing functions, MOCR, and MEMR.

Methods: Mice were exposed to the moderate noise (11.2 - 22. Read More

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http://dx.doi.org/10.1016/j.anl.2020.03.008DOI Listing

PIK3CA somatic mutation in sinonasal teratocarcinosarcoma.

Auris Nasus Larynx 2020 May 7. Epub 2020 May 7.

Department of Molecular Medicine, Sapienza University, Viale Regina Elena 291 Rome, Italy. Electronic address:

Sinonasal Teratocarcinosarcoma (SNTCS) is a rare and histologically heterogeneous tumor of uncertain origin and unknown molecular pathogenesis. Its location and aggressiveness, with frequent recurrences, high rate for metastasis and short mean survival, make SNTCS a tumor highly difficult to treat. Thus, the identification of underlying genetic changes could potentially provide successful adjuvant or alternative precision medicine treatment options for patients with this tumor. Read More

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http://dx.doi.org/10.1016/j.anl.2020.03.006DOI Listing
May 2020
1.004 Impact Factor

How to manage continuous positive airway pressure (CPAP) failure -hybrid surgery and integrated treatment.

Auris Nasus Larynx 2020 May 5. Epub 2020 May 5.

Department of Sports Sciences, University of Taipei, Taipei 111, Taiwan.

Obstructive sleep apnea (OSA) is a prevalent disease, which influences social relations and quality of life with major health impact. The etiology of OSA is multi-factorial involving both anatomical obstruction and physiological collapse of the upper airway during sleep with different proportion in individual patients. Continuous positive airway pressure (CPAP) is the gold standard and first-line treatment for OSA patients. Read More

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http://dx.doi.org/10.1016/j.anl.2020.03.007DOI Listing

Comparison of olfactory and taste functions between eosinophilic and non-eosinophilic chronic rhinosinusitis.

Auris Nasus Larynx 2020 May 5. Epub 2020 May 5.

Department of Otorhinolaryngology, Yonsei University College of Medicine, Republic of Korea; The Airway Mucus Institute, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address:

Objective: Most patients with chronic rhinosinusitis (CRS) complain of olfactory and/or taste dysfunctions. However, olfactory and taste dysfunctions depending on the subtype of CRS, classified as eosinophilic CRS (ECRS) and non-eosinophilic CRS (NCRS), have not been clearly reported. Therefore, the purpose of this study was to investigate the clinical features in olfactory and taste functions according to the subtype classified as ECRS and NCRS. Read More

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http://dx.doi.org/10.1016/j.anl.2020.04.006DOI Listing
May 2020
1.004 Impact Factor

Evaluation of temporal and suprasegmental auditory processing in patients with unilateral hearing loss.

Auris Nasus Larynx 2020 May 5. Epub 2020 May 5.

Department of Audiology, Faculty of Health Science, Hacettepe University, 06100 Ankara, Turkey.

Objectives: To determine the temporal order, resolution, and perception of prosody skills in Single-Sided Deafness (SSD) compared to an age- and sex-matched normal hearing group's same side ear and both ears.

Methods: This was a Case-Control study including 30 subjects with SSD, and age- and sex-matched 30 subjects with bilateral normal hearing (total of 60 subjects- mean age: 38.7 ± 11. Read More

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http://dx.doi.org/10.1016/j.anl.2020.04.009DOI Listing

Neuropilin-2 promotes growth and progression of papillary thyroid cancer cells.

Auris Nasus Larynx 2020 May 4. Epub 2020 May 4.

Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Chungnam National University School of Medicine, 266 Munhwa-ro, Jung-gu, Daejeon 301-721, South Korea. Electronic address:

Objective: Neuropilin-2 (NRP2) is a coreceptor of vascular endothelial growth factor-C/D (VEGF-C/D) and plays the important role in the development of lymphatic endothelial cells, as well as neuronal development. NRP2 is known to affect aggressiveness by increasing expression in various human cancers, but the role of NRP2 in thyroid cancer is not fully understood. The purpose of this study was to investigate the NRP2 expression and its role in regulating the tumor aggressiveness in the papillary thyroid carcinoma (PTC). Read More

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http://dx.doi.org/10.1016/j.anl.2020.03.013DOI Listing

Retrospective evaluation of secondary effects of hearing aids for tinnitus therapy in patients with hearing loss.

Auris Nasus Larynx 2020 May 4. Epub 2020 May 4.

Department of Otolaryngology - Head and Neck Surgery, Nara Medical University Hospital, Japan. Electronic address:

Objective: Acoustic therapies including hearing aids and tinnitus control instruments are widely used in Japan but without high levels of evidence. The outpatient hearing aid clinic at our institution fits patients with hearing aids and instructs patients on how to use them to control tinnitus if present. In this study, we examined the effects of this approach on tinnitus. Read More

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http://dx.doi.org/10.1016/j.anl.2020.03.005DOI Listing

An anatomical study of the anterior wall of the hypopharyngeal and the cervical esophageal junction.

Auris Nasus Larynx 2020 May 4. Epub 2020 May 4.

Department of Clinical Anatomy, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, Japan. Electronic address:

Objective: The upper esophageal sphincter plays a significant role by forming a physical barrier at the junction of the hypopharynx and the cervical esophagus. As few studies have focused on the ventral aspect of this junction, the contribution of the anterior wall of the cervical esophagus to upper esophageal sphincter function remains unknown. The purpose of this study was to examine the muscle fibers' arrangement at the junction, especially of those forming its anterior wall. Read More

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http://dx.doi.org/10.1016/j.anl.2020.04.005DOI Listing