203,918 results match your criteria Auris Nasus Larynx[Journal]

A Problem in Nosology.

John W Gittinger

Surv Ophthalmol 2021 May 10. Epub 2021 May 10.

Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA. Electronic address:

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Promoting Cultural Awareness, Professionalism, and Communication Skills in Medicine through Anatomy: The Deaf Culture Session.

Clin Anat 2021 May 13. Epub 2021 May 13.

College of Education and Human Development, Georgia State University, Atlanta, Georgia.

The anatomy curriculum is a place where professionalism can be learned and practiced, including training in cultural competence and communication skills for working with diverse populations. One population that has received little attention in terms of medical education are d/Deaf and hard of hearing patients, although there is much evidence to support health care disparities in this population. Several major contributing factors include differing views of deafness between medical professionals and those who are culturally Deaf, a lack of understanding of Deaf Culture and American Sign Language (ASL) by medical professionals, a lack of educational resources in ASL, and poor experiences in health care. Read More

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Nystagmus in adult patients with acute otitis media or otitis media with effusion without dizziness.

PLoS One 2021 13;16(5):e0250357. Epub 2021 May 13.

Department of Otorhinolaryngology-Head and Neck Surgery, Konkuk University Medical Center, Research Institute of Medical Science, Konkuk University School of Medicine, Seoul, Republic of Korea.

The present study aimed to investigate the incidence and patterns of nystagmus in adult patients with acute otitis media (AOM) or otitis media with effusion (OME) without dizziness or vertigo, and discuss possible mechanisms. From February 2018 to November 2018, 34 consecutive patients with AOM or OME without dizziness were included. Nystagmus was examined with video Frenzel glasses. Read More

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Predictors of hearing technology use in children.

Int J Audiol 2021 May 13:1-8. Epub 2021 May 13.

Department of Speech-Language Pathology and Audiology, University of Pretoria, Pretoria, South Africa.

Objective: To identify and describe predictors of daily hearing technology (HT) use in children.

Design: Retrospective review of clinical records. Multiple regression analyses were performed to identify predictors. Read More

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Numbers in short-term memory bias auditory spatial perception.

J Exp Psychol Hum Percept Perform 2021 Apr;47(4):616-633

Department of Psychology.

The cognitive penetration literature suggests that top-down knowledge influences perception, but whether such influences exist is controversial. We tested for top-down influences on perception by loading short-term memory with digits and then had participants make perceptual judgments to index spatial hearing. Memory of spatial number codes were predicted to bias spatial judgments to the left for small digits and rightward for larger digits. Read More

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Auditory selective adaptation moment by moment, at multiple timescales.

J Exp Psychol Hum Percept Perform 2021 Apr;47(4):596-615

Basque Center on Cognition, Brain and Language.

Over the course of a lifetime, adults develop perceptual categories for the vowels and consonants in their native language, based on the distribution of those sounds in their environment. However, in any given listening situation, the short-term distribution of sounds can cause changes in this long-term categorization. For example, if the same sound (the "adaptor") is heard many times in a short period of time, listeners and become less prone to hearing that sound. Read More

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Outcomes and complications of Traumatic Ear Lobe Repair Techniques: a Systematic Review.

J Cosmet Dermatol 2021 May 13. Epub 2021 May 13.

Department of Plastic and Reconstructive Surgery, Saint George Hospital University Medical Center, Beirut, Lebanon.

Background: Traumatic earlobe is a frequently encountered problem in our practice. Numerous techniques have been published in the past decades including case reports, retrospective reviews and prospective studies. However, to date, no study has investigated the overall complications or satisfaction rates associated with the wide spectrum of techniques. Read More

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Treatment with somatostatin analogues and PRRT in metastatic middle ear adenoma with neuroendocrine features.

Endocrinol Diabetes Metab Case Rep 2021 May 1;2021. Epub 2021 May 1.

Department of Internal Medicine, Section of Endocrinology, ENETS Center of Excellence, Erasmus Cancer Institute, Erasmus Medical Center, Rotterdam, The Netherlands.

Summary: Middle ear adenomas with neuroendocrine features (ANEF) are rare, with an estimated 150 reported cases. They usually pursue an indolent clinical course. Four reported cases of middle ear ANEF with distant metastases were treated with surgery, external beam radiation therapy (EBRT) and chemotherapy. Read More

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The impact of Allergic Rhinitis in clinical practice: An International Survey.

J Biol Regul Homeost Agents 2021 Jan-Feb;35(1 Suppl. 2):39-43

Consultant allergist, Casa di Cura Villa Montallegro, Genoa, Italy.

Allergic rhinitis (AR) is a frequent disease caused by an IgE-mediated inflammation of the nose and characterized by typical symptoms. Diagnostic workup is directed to document the production of specific IgE (sensitization). Clinical management aims to relieve symptoms, resolve allergic inflammation, use medications, and potentially induce allergen tolerance, using allergen immunotherapy (AIT). Read More

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Malignancies requiring temporal bone resection: An Australian single-institution experience.

ANZ J Surg 2021 May 12. Epub 2021 May 12.

Queensland Skull Base Unit and Department of Otolaryngology, Head and Neck Surgery, Princess Alexandra Hospital, Brisbane, Queensland, Australia.

Background: Malignancies in and around the temporal bone are aggressive and difficult to manage. In Queensland (Australia), where skin cancer rates are exceedingly high, tumours extending to the temporal bone from surrounding structures occur more commonly than primary cancers. Yet, a paucity of evidence exists as to their management and outcomes. Read More

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Unexpected difficult tracheal intubation secondary to subglottic stenosis leading to emergency front-of-neck airway.

Anaesth Rep 2021 Jan-Jun;9(1):90-94. Epub 2021 May 9.

Department of Anaesthesia Prince Charles Hospital Llantrisant UK.

A 26-year-old woman presenting for an elective day case procedure under general anaesthesia had undiagnosed subglottic stenosis leading to a life threatening airway emergency requiring emergency front-of-neck airway. We outline the case and discuss key anaesthetic considerations in subglottic stenosis, including concerning features of a medical/anaesthetic history and the potential for rapid deterioration of a stenotic airway following manipulation. We also consider the effect of anaesthesia on the calibre of subglottic stenosis and the effects of positive pressure ventilation. Read More

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Laryngectomy with a Tritube and flow-controlled ventilation.

Anaesth Rep 2021 Jan-Jun;9(1):86-89. Epub 2021 May 7.

Department of Head and Neck Surgery Poole Hospital NHS Trust Poole UK.

We describe the novel use of the TriTube and Evone ventilator (Ventinova, Eindhoven, Netherlands) to facilitate curative resection of a transglottic squamous cell carcinoma. A 43-year-old man presented with acute laryngeal and subglottic airway obstruction secondary to a stage 4 transglottic squamous cell carcinoma. The patient underwent magnetic resonance imaging followed by a diagnostic panendoscopy. Read More

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Fundus albipunctatus photoreceptor microstructure revealed using adaptive optics scanning light ophthalmoscopy.

Am J Ophthalmol Case Rep 2021 Jun 16;22:101090. Epub 2021 Apr 16.

Icahn School of Medicine at Mount Sinai and New York Eye and Ear Infirmary of Mount Sinai, Department of Ophthalmology, New York, NY, USA.

Purpose: Fundus albipunctatus is an inherited cause of congenital stationary night blindness. The objective of this report is to describe structural changes occurring in a macular phenotype of a novel RDH5 mutation producing fundus albipunctatus using high-resolution imaging. A 62-year-old male with longstanding night blindness underwent imaging and genetic evaluation. Read More

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On the locus of talker-specificity effects in spoken word recognition: an ERP study with dichotic priming.

Lang Cogn Neurosci 2017 8;32(10):1273-1289. Epub 2017 Jun 8.

Brain and Language Research Institute, Aix-Marseille Université, Aix-en-Provence, France.

We used event-related potentials to examine the precise moment at which talker-specific information comes into play during spoken word recognition. Dichotic repetition priming was examined with primes presented in the left unattended ear and targets presented in the right attended ear, and we manipulated both word frequency and talker identity. A clear repetition priming effect was observed in an early time-window spanning 100-200 ms post-target onset, and the effect continued after target word offset in a time-window between 650 and 800 ms. Read More

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Saccade Landing Point Prediction Based on Fine-Grained Learning Method.

IEEE Access 2021 1;9:52474-52484. Epub 2021 Apr 1.

Schepens Eye Research Institute, Massachusetts Eye and Ear, Boston, MA 02114, USA.

The landing point of a saccade defines the new fixation region, the new region of interest. We asked whether it was possible to predict the saccade landing point early in this very fast eye movement. This work proposes a new algorithm based on LSTM networks and a fine-grained loss function for saccade landing point prediction in real-world scenarios. Read More

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Interfering microRNA-410 attenuates atherosclerosis via the HDAC1/KLF5/IKBα/NF-κB axis.

Mol Ther Nucleic Acids 2021 Jun 13;24:646-657. Epub 2021 Mar 13.

Department of Ear-Nose-Throat, The Second Hospital of Jilin University, Changchun 130041, Jilin Province, PR China.

MicroRNA (miR)-410 plays a potential role in the pathogenesis of atherosclerosis. The current study mainly focuses on the underlying mechanism of miR-410/histone deacetylase 1 (HDAC1)/KLF5/nuclear factor κB (NF-κB) inhibitor α (IKBα)/NF-κB axis in atherosclerosis. miR-410 expression was determined using quantitative real-time PCR in both mouse models of atherosclerosis and human umbilical endothelial cells (HUVECs) treated with oxidized low-density lipoprotein (ox-LDL). Read More

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Evolution of Old World Equus and origin of the zebra-ass clade.

Sci Rep 2021 May 12;11(1):10156. Epub 2021 May 12.

Laboratory of Evolutionary Biology, Department of Anatomy, College of Medicine, 520 W St. N.W, Washington, DC, 20059, USA.

Evolution of the genus Equus has been a matter of long debate with a multitude of hypotheses. Currently, there is no consensus on either the taxonomic content nor phylogeny of Equus. Some hypotheses segregate Equus species into three genera, Plesippus, Allohippus and Equus. Read More

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Duplicated internal auditory canal with dysplastic ossicles and microtia: role of high-resolution CT and MRI.

BMJ Case Rep 2021 May 12;14(5). Epub 2021 May 12.

Radiodiagnosis, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India

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Dropped Nucleus during Cataract Surgery in South India: Incidence, Risk Factors, and Outcomes.

Ophthalmic Epidemiol 2021 May 12:1-8. Epub 2021 May 12.

Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA.

: To determine incidence, risk factors for, and outcomes of dropped nucleus (DN) during cataract surgery.: This is a matched case-control study at the Aravind Eye Hospital in Madurai, India. Out of 184 consecutive DN cases, 171 were included. Read More

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Specific abnormalities in white matter pathways as interface to small vessels disease and cognition in CADASIL individuals.

Brain Connect 2021 May 12. Epub 2021 May 12.

Harvard Medical School, 1811, Psychiatry and Neurology, 100 1st Avenue, suite 101, Charlestown, Boston, Massachusetts, United States, 02129;

Background: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is characterized by leukoencephalopathy leading to cognitive impairment. Subtle cognitive deficits can be observed early in the course of the disease, prior to the occurrence of the first stroke. Therefore, markers that can predict disease progression at this early stage, when interventions are likely to alter disease course, are needed. Read More

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Impaired glucose-1,6-biphosphate production due to bi-allelic PGM2L1 mutations is associated with a neurodevelopmental disorder.

Am J Hum Genet 2021 May 5. Epub 2021 May 5.

de Duve Institute, UCLouvain, 1200 Brussels, Belgium. Electronic address:

We describe a genetic syndrome due to PGM2L1 deficiency. PGM2 and PGM2L1 make hexose-bisphosphates, like glucose-1,6-bisphosphate, which are indispensable cofactors for sugar phosphomutases. These enzymes form the hexose-1-phosphates crucial for NDP-sugars synthesis and ensuing glycosylation reactions. Read More

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Risk factors for presence of cystoid macular edema following rhegmatogenous retinal detachment surgery.

Curr Eye Res 2021 May 12. Epub 2021 May 12.

Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, PA.

Purpose: Cystoid macular edema (CME) following cataract surgery is a well-known entity. Less is known regarding the risk factors of developing CME following repair of rhegmatogenous retinal detachments (RRD).

Methods: This was a multi-institutional study of primary RRD surgeries from 1/1/2015 through 12/31/2015. Read More

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Cultured human uveal melanocytes express/secrete CXCL1 and CXCL2 constitutively and increased by lipopolysaccharide via activation of Toll-like receptor 4.

Curr Eye Res 2021 May 12. Epub 2021 May 12.

Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan.

Purpose: Lipopolysaccharide (LPS) can activate Toll-like receptor 4 (TLR4) and increase the expression of CXCL1 and CXCL2, the potent neutrophils chemoattractants, in various cell types. These effects have not been previously reported in the uveal melanocytes. This study was designed to investigate the effects of LPS on the activation of TLR4 and expression of CXCL1/CXCL2 in cultured human uveal melanocytes and the relevant signal pathways. Read More

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Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images.

PLoS Genet 2021 May 12;17(5):e1009497. Epub 2021 May 12.

School of Life Course Sciences, Section of Ophthalmology, King's College London, London, United Kingdom.

Optical Coherence Tomography (OCT) enables non-invasive imaging of the retina and is used to diagnose and manage ophthalmic diseases including glaucoma. We present the first large-scale genome-wide association study of inner retinal morphology using phenotypes derived from OCT images of 31,434 UK Biobank participants. We identify 46 loci associated with thickness of the retinal nerve fibre layer or ganglion cell inner plexiform layer. Read More

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COVID-19 Retinal Findings in Patients Admitted to Intensive Care Units and Wards.

Ocul Immunol Inflamm 2021 May 12:1-4. Epub 2021 May 12.

São Paulo Hospital, Paulista School of Medicine, Federal University of São Paulo, Sao Paulo, Brazil.

The main purpose of this study was to investigate ocular clinical findings in patients with confirmed COVID-19 infection, of various levels of disease severity, who required mechanical ventilation and admission to intensive care units or specialized wards. Longitudinal, observational study conducted from March 2020 to June 2020. Color fundus and red-free photography were performed in both eyes following pupillary dilation. Read More

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Accurate Operative Time Prediction in Thyroid Surgery: A Rural Tertiary Care Facility Experience.

Ear Nose Throat J 2021 May 12:1455613211016702. Epub 2021 May 12.

Department of Otolaryngology-Head and Neck/Facial Plastic Surgery, 21599Geisinger Medical Center, Danville, PA, USA.

Objective: To determine whether surgeons can estimate thyroid operative time more accurately than a system-generated average time estimate.

Methods: Four otolaryngologists at a single institution with extensive endocrine surgery experience were asked to predict their operative times for all eligible thyroid surgeries. These estimates were compared to system-generated operative time predications based on averaging the surgeon's previous 10 cases with the same Current Procedural Terminology code. Read More

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Does Prematurity Play a Role in Newborn Microtia-Anotia?

Ann Otol Rhinol Laryngol 2021 May 12:34894211015735. Epub 2021 May 12.

Department of Otolaryngology - Head and Neck Surgery, Boston Medical Center, Boston, MA, USA.

Objective: Microtia-anotia (MA) describes a range of external ear anomalies which is commonly associated with various syndromes and malformations of the head and neck. Previous studies have suggested a strong association between MA and male sex, maternal diabetes, and Hispanic race/ethnicity. This study seeks to evaluate the associations between MA and preterm newborns in the United States. Read More

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Innate Immune Invisible Ultrasmall Gold Nanoparticles-Framework for Synthesis and Evaluation.

ACS Appl Mater Interfaces 2021 May 12. Epub 2021 May 12.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge CB3 0AS, U.K.

Nanomedicine is seen as a potential central player in the delivery of personalized medicine. Biocompatibility issues of nanoparticles have largely been resolved over the past decade. Despite their tremendous progress, less than 1% of applied nanosystems can hit their intended target location, such as a solid tumor, and this remains an obstacle to their full ability and potential with a high translational value. Read More

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Positive correlation between Candida auris skin-colonization burden and environmental contamination at a ventilator-capable skilled nursing facility in Chicago.

Clin Infect Dis 2021 May 12. Epub 2021 May 12.

Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Background: Candida auris is an emerging multidrug-resistant yeast that contaminates healthcare environments causing healthcare-associated outbreaks. The mechanisms facilitating contamination are not established.

Methods: C. Read More

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