3,348 results match your criteria Auris Nasus Larynx[Journal]


Facial nerve course in the temporal bone: Anatomical relationship between the tympanic and mastoid portions for safe ear surgery.

Auris Nasus Larynx 2020 May 28. Epub 2020 May 28.

Department of Otolaryngology - Head & Neck Surgery, Osaka Medical College, Takatsuki, Japan.

Objective: Avoidance of iatrogenic injury to the facial nerve is crucial during ear surgery. The anatomical relationship between the tympanic portion of the facial canal (FC) and the mastoid portion of the facial nerve was analyzed using multi-slice computed tomography (CT) scans to avoid iatrogenic facial nerve injury.

Methods: In total, 364 ears of 351 patients who underwent CT scans were enrolled. Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.002DOI Listing

Fibrous dysplasia limited to an ossicle.

Auris Nasus Larynx 2020 May 27. Epub 2020 May 27.

Beckman Laser Institute Korea, College of Medicine, Dankook University, Cheonan, South Korea; Department of Otolaryngology-Head & Neck Surgery, College of Medicine, Dankook University Cheonan, South Korea. Electronic address:

Fibrous dysplasia is an unusual pathologic condition caused by abnormal bone metabolism. Temporal bone involvement is often seen, but it is uncommon to find fibrous dysplasia limited to the middle ear, especially originating in and confined to a single ossicle. Here we report a case of osteofibrous dysplasia limited exclusively to an ossicle (malleus) causing gradual conductive hearing loss, which recovered after eventual complete removal of the dysplastic area. Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.005DOI Listing

Therapeutic effect of Nivolumab for advanced / recurrent temporal bone squamous cell carcinoma.

Auris Nasus Larynx 2020 May 20. Epub 2020 May 20.

Department Otolaryngology Head and Neck Surgery, Kyushu University, 3-1-1 Maidashi, Fukuoka, Japan.

Objective: The immune checkpoint inhibitor Nivolumab was approved for the treatment of platinum-refractory head and neck squamous cell carcinoma (SCC), expanding the treatment options for recurrent or advanced head and neck SCC. However, since temporal bone squamous cell carcinoma (TB-SCC) is very rare cancer, the effectiveness of Nivolumab remains unclear. We investigated the effects of Nivolumab for TB-SCC. Read More

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http://dx.doi.org/10.1016/j.anl.2020.03.011DOI Listing

Barrier device prototype for open tracheotomy during COVID-19 pandemic.

Auris Nasus Larynx 2020 May 8. Epub 2020 May 8.

Department of Head and Neck Surgery, Walter Cantidio University Hospital of Universidade Federal do Ceara Medical School, Fortaleza, Ceara, Brazil.

Objective: To present a low-cost prototype for a barrier enclosure device which can be used during open surgeries such as tracheotomy.

Methods: We provide detailed description of a novel device called COVID-Box, developed by The Surgical Airway Team for COVID-19 Pandemic, a temporary task force formed by Walter Cantídio University Hospital. Safety guidelines for performing tracheotomies in COVID-19 patients are also stated. Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205665PMC

Overall survival and PD-L1 expression in patients with recurrent or metastatic head and neck cancer treated with nivolumab.

Auris Nasus Larynx 2020 May 18. Epub 2020 May 18.

Department of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.

Objective: Our facility measures programmed cell death ligand 1 (PD-L1) expression in all patients before administering nivolumab. The aim of the present study is to clarify the association between overall survival (OS) and PD-L1 expression.

Patients And Methods: Subjects in this study were 52 patients with R/M-HNC cancer (45 men, 7 women) administered nivolumab in our facility between June 1, 2017 and January 31, 2019. Read More

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http://dx.doi.org/10.1016/j.anl.2020.04.001DOI Listing

The impact of preoperative screening system on head and neck cancer surgery during the COVID-19 pandemic: Recommendations from the nationwide survey in Japan.

Auris Nasus Larynx 2020 May 16. Epub 2020 May 16.

Department of Head and Neck Surgery, Miyagi Cancer Center, Natori, Miyagi, Japan.

Objective: the pandemic of coronavirus disease 2019 (COVID-19), hospitals worldwide are at risk of nosocomial infection. Preoperative identification of COVID-19 in patients who are scheduled to be admitted to the hospital is essential to preventing the collapse of medical facility. In Japan, the preoperative observation and screening tests with the RT-PCR testing for the new coronavirus (SARS-CoV-2) and chest CT scan are recommended for head and neck cancer surgery during the COVID-19 pandemic. Read More

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http://dx.doi.org/10.1016/j.anl.2020.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229909PMC

Trends in complications after functional endoscopic sinus surgery in Japan: A comparison with a previous study (2007-2013vs. 2013-2017).

Auris Nasus Larynx 2020 May 14. Epub 2020 May 14.

Department of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

Objective: Functional endoscopic sinus surgery (FESS) for chronic rhinosinusitis is considered safe and is widely performed. Techniques and devices for this type of surgery have recently been updated. The purpose of this study was to describe the proportions of complications after FESS (2013-2017) and to compare the results with those from our previous study (2007-2013). Read More

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http://dx.doi.org/10.1016/j.anl.2020.04.003DOI Listing

Resection of carcinoma of the external auditory canal in a patient with a high jugular bulb using temporal craniotomy.

Auris Nasus Larynx 2020 May 10. Epub 2020 May 10.

Department of Head and Neck Surgery, National Cancer Center Hospital, 5-1-1 Tsukiji, chuo, Tokyo 104-0045, Japan.

External auditory canal (EAC) carcinoma is a rare and unusual malignancy. The complex anatomy and relationship between the tumor and surrounding tissues in a limited space render it difficult to attain safe resection margins during surgery. A high jugular bulb (HJB) is one such anatomical variation that has important surgical implications that complicate the surgical procedure for EAC carcinoma. Read More

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http://dx.doi.org/10.1016/j.anl.2020.03.010DOI Listing

Long-term moderate noise exposure enhances the medial olivocochlear reflex.

Auris Nasus Larynx 2020 May 10. Epub 2020 May 10.

ENT Institute, Eye & ENT Hospital of Fudan University, Fenyang Road 83, Shanghai 200031, PR China; NHC Hearing Medicine Key Laboratory (Fudan University), Shanghai, PR China. Electronic address:

Objective: To investigate the effects of long-term moderate noise on hearing functions, MOCR, and MEMR.

Methods: Mice were exposed to the moderate noise (11.2 - 22. Read More

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http://dx.doi.org/10.1016/j.anl.2020.03.008DOI Listing

PIK3CA somatic mutation in sinonasal teratocarcinosarcoma.

Auris Nasus Larynx 2020 May 7. Epub 2020 May 7.

Department of Molecular Medicine, Sapienza University, Viale Regina Elena 291 Rome, Italy. Electronic address:

Sinonasal Teratocarcinosarcoma (SNTCS) is a rare and histologically heterogeneous tumor of uncertain origin and unknown molecular pathogenesis. Its location and aggressiveness, with frequent recurrences, high rate for metastasis and short mean survival, make SNTCS a tumor highly difficult to treat. Thus, the identification of underlying genetic changes could potentially provide successful adjuvant or alternative precision medicine treatment options for patients with this tumor. Read More

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http://dx.doi.org/10.1016/j.anl.2020.03.006DOI Listing
May 2020
1.004 Impact Factor

How to manage continuous positive airway pressure (CPAP) failure -hybrid surgery and integrated treatment.

Auris Nasus Larynx 2020 May 5. Epub 2020 May 5.

Department of Sports Sciences, University of Taipei, Taipei 111, Taiwan.

Obstructive sleep apnea (OSA) is a prevalent disease, which influences social relations and quality of life with major health impact. The etiology of OSA is multi-factorial involving both anatomical obstruction and physiological collapse of the upper airway during sleep with different proportion in individual patients. Continuous positive airway pressure (CPAP) is the gold standard and first-line treatment for OSA patients. Read More

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http://dx.doi.org/10.1016/j.anl.2020.03.007DOI Listing

Comparison of olfactory and taste functions between eosinophilic and non-eosinophilic chronic rhinosinusitis.

Auris Nasus Larynx 2020 May 5. Epub 2020 May 5.

Department of Otorhinolaryngology, Yonsei University College of Medicine, Republic of Korea; The Airway Mucus Institute, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address:

Objective: Most patients with chronic rhinosinusitis (CRS) complain of olfactory and/or taste dysfunctions. However, olfactory and taste dysfunctions depending on the subtype of CRS, classified as eosinophilic CRS (ECRS) and non-eosinophilic CRS (NCRS), have not been clearly reported. Therefore, the purpose of this study was to investigate the clinical features in olfactory and taste functions according to the subtype classified as ECRS and NCRS. Read More

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http://dx.doi.org/10.1016/j.anl.2020.04.006DOI Listing
May 2020
1.004 Impact Factor

Evaluation of temporal and suprasegmental auditory processing in patients with unilateral hearing loss.

Auris Nasus Larynx 2020 May 5. Epub 2020 May 5.

Department of Audiology, Faculty of Health Science, Hacettepe University, 06100 Ankara, Turkey.

Objectives: To determine the temporal order, resolution, and perception of prosody skills in Single-Sided Deafness (SSD) compared to an age- and sex-matched normal hearing group's same side ear and both ears.

Methods: This was a Case-Control study including 30 subjects with SSD, and age- and sex-matched 30 subjects with bilateral normal hearing (total of 60 subjects- mean age: 38.7 ± 11. Read More

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http://dx.doi.org/10.1016/j.anl.2020.04.009DOI Listing

Neuropilin-2 promotes growth and progression of papillary thyroid cancer cells.

Auris Nasus Larynx 2020 May 4. Epub 2020 May 4.

Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Chungnam National University School of Medicine, 266 Munhwa-ro, Jung-gu, Daejeon 301-721, South Korea. Electronic address:

Objective: Neuropilin-2 (NRP2) is a coreceptor of vascular endothelial growth factor-C/D (VEGF-C/D) and plays the important role in the development of lymphatic endothelial cells, as well as neuronal development. NRP2 is known to affect aggressiveness by increasing expression in various human cancers, but the role of NRP2 in thyroid cancer is not fully understood. The purpose of this study was to investigate the NRP2 expression and its role in regulating the tumor aggressiveness in the papillary thyroid carcinoma (PTC). Read More

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http://dx.doi.org/10.1016/j.anl.2020.03.013DOI Listing

Retrospective evaluation of secondary effects of hearing aids for tinnitus therapy in patients with hearing loss.

Auris Nasus Larynx 2020 May 4. Epub 2020 May 4.

Department of Otolaryngology - Head and Neck Surgery, Nara Medical University Hospital, Japan. Electronic address:

Objective: Acoustic therapies including hearing aids and tinnitus control instruments are widely used in Japan but without high levels of evidence. The outpatient hearing aid clinic at our institution fits patients with hearing aids and instructs patients on how to use them to control tinnitus if present. In this study, we examined the effects of this approach on tinnitus. Read More

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http://dx.doi.org/10.1016/j.anl.2020.03.005DOI Listing

An anatomical study of the anterior wall of the hypopharyngeal and the cervical esophageal junction.

Auris Nasus Larynx 2020 May 4. Epub 2020 May 4.

Department of Clinical Anatomy, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, Japan. Electronic address:

Objective: The upper esophageal sphincter plays a significant role by forming a physical barrier at the junction of the hypopharynx and the cervical esophagus. As few studies have focused on the ventral aspect of this junction, the contribution of the anterior wall of the cervical esophagus to upper esophageal sphincter function remains unknown. The purpose of this study was to examine the muscle fibers' arrangement at the junction, especially of those forming its anterior wall. Read More

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http://dx.doi.org/10.1016/j.anl.2020.04.005DOI Listing

Availability of audiological evaluation for the differential diagnosis of clinical otosclerosis.

Auris Nasus Larynx 2020 May 1. Epub 2020 May 1.

Department of Otorhinolaryngology, Aichi Medical University School of Medicine, 1-1 Yazakokarimata, Nagakute 480-1195, Aichi, Japan.

Objective: The availability of an audiological evaluation for the differential diagnosis of clinical otosclerosis (OS) was examined.

Methods: Included were 98 patients (107 ears) with OS and 19 patients (20 ears) with incudostapedial disconnection (ISD) diagnosed by surgery between 2009 and 2017 at Aichi University Hospital. Results of preoperative pure-tone audiometry and impedance audiometry were analyzed. Read More

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http://dx.doi.org/10.1016/j.anl.2020.03.009DOI Listing

Suppurative cervical lymphadenitis in adult: An analysis of predictors for surgical drainage.

Auris Nasus Larynx 2020 May 1. Epub 2020 May 1.

Otolaryngology Unit, Phayao Hospital, 269 moo 11, Tumbon Bantom, Muang Phayao, Phayao 56000, Thailand.

Objective: Lymphadenitis can be treated successfully by empirical antibiotic therapy. However, inflamed lymph nodes can progress into an abscess with local and/or systemic reaction, which requires more complex treatment strategies. The study aim to analyze possible predictors for abscess formation within inflamed nodes that require surgical drainage. Read More

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http://dx.doi.org/10.1016/j.anl.2020.04.007DOI Listing

Reshaping head and neck reconstruction policy during the COVID-19 pandemic peak: Experience in a front-line institution.

Auris Nasus Larynx 2020 Apr 23. Epub 2020 Apr 23.

Unit of Otorhinolaryngology - Head and Neck Surgery, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, ASST Spedali Civili of Brescia, 25121 Brescia, Italy.

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http://dx.doi.org/10.1016/j.anl.2020.04.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177088PMC

Pathological evaluation of radiotherapy and concomitant intraarterial cisplatin for maxillary sinus cancer.

Auris Nasus Larynx 2020 Apr 22. Epub 2020 Apr 22.

Department of Otolaryngology-Head and Neck Surgery, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 2-5-1 Shikata-Cho, Kita-ku, Okayama 700-8558, Japan.

Objective: Since 2010, we have mainly performed surgical treatment following radiotherapy and concomitant intraarterial cisplatin (RADPLAT) for locally advanced maxillary sinus cancer (MSC). The present study investigated treatment results and pathological evaluations following RADPLAT for MSC.

Methods: Pathological response to RADPLAT was evaluated using surgical specimens. Read More

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http://dx.doi.org/10.1016/j.anl.2020.04.004DOI Listing

Anesthetic and surgical management of tracheostomy in a patient with COVID-19.

Auris Nasus Larynx 2020 Apr 18. Epub 2020 Apr 18.

Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, 65, Tsurumai-cho, Showa-ku, Nagoya 466-8550 Japan.

Objective: The ongoing pandemic coronavirus disease-2019 (COVID-19) infection causes severe respiratory dysfunction and has become an emergent issue for worldwide healthcare. Since COVID-19 spreads through contact and droplet infection routes, careful attention to infection control and surgical management is important to prevent cross-contamination of patients and medical staff. Tracheostomy is an effective method to treat severe respiratory dysfunction with prolonged respiratory management and should be performed as a high-risk procedure METHOD: The anesthetic and surgical considerations in this case involved difficult goals of the patient safety and the management of infection among health care workers. Read More

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http://dx.doi.org/10.1016/j.anl.2020.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165273PMC

Unilateral vocal fold palsy & dysphagia: A review.

Authors:
Jennifer F Ha

Auris Nasus Larynx 2020 Apr 6. Epub 2020 Apr 6.

Department of Paediatrics Otolaryngology Head & Neck Surgery, Perth Children's Hospital, Roberts Road, Nedlands 6009, Australia; Murdoch ENT, Wexford Medical Centre, St John of God Hospital (Murdoch), Suite 17-18, Level 1, 3 Barry Marshall Parade, Murdoch 6150, Australia; School of Surgery, University of Western Australia, Stirling Highway, Crawley 6009, Australia; St John of God Hospital (Murdoch), Wexford Medical Center, Suite 17-18, Level 1, 3 Barry Marshall Parade, Murdoch 6150, Australia. Electronic address:

Objectives: Unilateral vocal fold palsy (UVFP) is the commonest neurological laryngeal disorder. Much of the research have focused on its implication on voice, with limited data on its impact on swallowing. The aim of this paper is to examine the current evidence on the pathophysiology, impact and management of UVFP and swallowing. Read More

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http://dx.doi.org/10.1016/j.anl.2020.03.001DOI Listing

Body plethysmography for measuring airway resistance in patients with bilateral vocal fold immobility.

Auris Nasus Larynx 2020 Apr 6. Epub 2020 Apr 6.

Department of Otorhinolaryngology, Head and Neck Surgery, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.

Objective: This study investigated the reliability of body plethysmography in comparison to spirometry in objectively measuring upper airway functions.

Methods: The study population consisted of 53 participants, 23 patients with BVFI after endolaryngeal laser posterior cordectomy and 30 healthy volunteers. All of them had body plethysmography (airway resistance, Raw), spirometry (ratio of forced expiratory flow at 50% to forced inspiratory flow at 50%, FEF/FIF and peak inspiratory flow, PIF), 6 min-walking-test (6MWT) and Medical Research Council (MRC) dyspnea scale measurements. Read More

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http://dx.doi.org/10.1016/j.anl.2020.03.004DOI Listing

Typewriter tinnitus: An investigative comparison with middle ear myoclonic tinnitus and its long-term therapeutic response to carbamazepine.

Auris Nasus Larynx 2020 Apr 5. Epub 2020 Apr 5.

College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. Electronic address:

Objectives: Due to its rarity and similar sound, typewriter tinnitus (TT) can be misdiagnosed as middle ear myoclonic tinnitus (MEMT). We aim to clarify the characteristics of TT compared to MEMT, and the long-term therapeutic response to carbamazepine.

Methods: Fourteen patients with TT and 28 patients with MEMT were enrolled. Read More

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http://dx.doi.org/10.1016/j.anl.2020.01.005DOI Listing

Dizziness after an earthquake tilted the house.

Auris Nasus Larynx 2020 Apr 5. Epub 2020 Apr 5.

Department of Otolaryngology, Toho University Sakura Medical Center, Sakura City, Chiba 285-0841, Japan. Electronic address:

Major earthquakes occasionally cause vertiginous attacks or persistent dizziness, which may be related to the effects of autonomic stress on equilibrium function and/or psychological factors. We present the case of a 73-year-old woman who suffered from persistent dizziness for 1 year, during which she lived in a house tilted by the great 2011 Tōhoku earthquake. An electronystagmogram demonstrated leftward horizontal and downbeat nystagmus in the sitting and supine positions with eyes closed. Read More

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http://dx.doi.org/10.1016/j.anl.2019.12.005DOI Listing

Treatment of oral ranula in HIV-positive patient.

Auris Nasus Larynx 2020 Apr 5. Epub 2020 Apr 5.

Division of Otolaryngology, Tohoku Medical and Pharmaceutical University, Sendai 981-0905, Japan. Electronic address:

HIV-associated salivary gland disease refers to the pathology in head and neck lesions such as ranula, salivary gland swelling, xerostomia, and benign lymphoepithelial cysts in the parotid gland. Here, we present a unique case of the ranula patient with HIV infection treated with OK-423 sclerotherapy. Case report: The patient was a 42-year-old Japanese male with a few months history of oral floor swelling. Read More

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http://dx.doi.org/10.1016/j.anl.2020.02.009DOI Listing

Cochlear implantation in patient with Charcot-Marie-Tooth disease.

Auris Nasus Larynx 2020 Apr 4. Epub 2020 Apr 4.

Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Two patients with auditory neuropathy spectrum disorder (ANSD) considered to be associated with Charcot-Marie-Tooth (CMT) are reported. In case 1, a 23-year-old man presented with progressive bilateral sensorineural hearing loss (SNHL) from 10 years of age and was diagnosed with ANSD. He was later diagnosed with CMT by neurological testing. Read More

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http://dx.doi.org/10.1016/j.anl.2020.03.003DOI Listing

Tongue imaging during drug-induced sleep ultrasound in obstructive sleep apnea patients.

Auris Nasus Larynx 2020 Apr 2. Epub 2020 Apr 2.

Department of Otolaryngology - Head and Neck Surgery, Sleep Center, Linkou-Chang Gung Memorial Hospital, Taoyuan 33305, Taiwan ROC; College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan ROC. Electronic address:

Objectives: The aims of this study are to examine the changes of tongue thickness and distance of two lingual arteries through drug-induced sleep ultrasound, and explore the relationship between sonographic measurements and clinical data.

Materials And Methods: A total of 26 confirmed obstructive sleep apnea patients were recruited in this one-year study. All patients received ultrasound examination twice (wakefulness and drug-induced sleep) in sleep center under level 1 polysomnographic monitor. Read More

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http://dx.doi.org/10.1016/j.anl.2020.02.012DOI Listing

A Japanese nationwide survey for evaluation of the comprehensibility of alternative audiometry display formats: Insight into otolaryngologists' cognitive processes.

Auris Nasus Larynx 2020 Mar 31. Epub 2020 Mar 31.

Department of Health Care Services Management, Nihon University School of Medicine, 30-1, Oyaguchikami-cho, Itabashi, Tokyo, 173-8610, Japan.

Objective: The present study aimed to elucidate opinions regarding comprehensibility of audiometry display formats among otolaryngologists in Japan, and to identify the characteristics of otolaryngologists' cognitive processes for audiometry.

Methods: We conducted a cross-sectional nationwide questionnaire-based mail survey regarding the comprehensibility of audiometry display formats among 543 Japanese otolaryngologists. Of 543 otolaryngologists to whom the questionnaires were mailed, 137 replied to the questions. Read More

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http://dx.doi.org/10.1016/j.anl.2020.03.002DOI Listing

Superior laryngeal nerve transection for neuropathic cough: A pilot study.

Auris Nasus Larynx 2020 Mar 31. Epub 2020 Mar 31.

Washington University in St. Louis School of Medicine, Department of Otolaryngology-Head & Neck Surgery, St. Louis, MO. Electronic address:

Objective: To describe a novel surgical therapy for the treatment of medically refractory neuropathic cough, in which carefully selected subjects undergo surgical transection of the internal branch of the superior laryngeal nerve (iSLN).

Methods: Subjects with a diagnosis of neuropathic cough, who were not improved after two medication trials, underwent iSLN block with local anesthetic in the office. While anesthetized, they underwent provocative testing to determine whether the nerve block improved their symptoms; if so, a modified barium swallow study (MBSS) was performed to determine whether they still swallowed safely without supraglottic sensation. Read More

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http://dx.doi.org/10.1016/j.anl.2020.02.016DOI Listing

Imbalance, motion sensitivity, anxiety and handicap in vestibular migraine and migraine only patients.

Auris Nasus Larynx 2020 Mar 13. Epub 2020 Mar 13.

Department of Neurology, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.

Objective: The aim of this study is to compare the balance ability, anxiety level and motion sickness susceptibility in Vestibular Migraine (VM) patients, migraineurs without history of vertigo (Migraine-only, MO) and healthy controls (HC). We tested the hypothesis that VM patients have worse balance performance and higher anxiety level and motion sickness than MO and HC group.

Methods: This cross-sectional study included of 123 definite VM patients, 58 MO patients and 49 HCs. Read More

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http://dx.doi.org/10.1016/j.anl.2020.02.015DOI Listing

Left non-recurrent inferior laryngeal nerve in a patient with right-sided aortic arch and aberrant left subclavian artery.

Auris Nasus Larynx 2020 Mar 13. Epub 2020 Mar 13.

Department of Otolaryngology-Head and Neck Surgery, Kobe University Graduate School of Medicine, Kobe,7-5-2 Kusunoki-Cho, Chuo-ku, Kobe 650-0017, Japan.

Non-recurrent inferior laryngeal nerve (NRILN) is rare but one of the important anatomical variations in thyroid and parathyroid surgery. Almost all cases were observed on the right side with aberrant right subclavian artery and left NRILN have been reported in only five cases so far. Here, we reported a 38 year-old Japanese male with left NRILN accompanying adenomatous goiter. Read More

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http://dx.doi.org/10.1016/j.anl.2020.02.011DOI Listing

Tympanic membrane findings of otitis media with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (OMAAV).

Auris Nasus Larynx 2020 Mar 12. Epub 2020 Mar 12.

Department of Otolaryngology Head and Neck Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

Objective: Otitis media with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (OMAAV) is characterized by adult otitis media refractory to conventional treatments. OMAAV is either an aural manifestation of existing ANCA-associated vasculitis (AAV) or an initial aural manifestation of AAV. OMAAV occasionally causes an irreversible profound sensorineural hearing loss that may require a cochlear implant even in the latter case. Read More

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http://dx.doi.org/10.1016/j.anl.2020.02.017DOI Listing

Evaluation of the structure of the otoconial layer using micro-computed tomography.

Auris Nasus Larynx 2020 Mar 13. Epub 2020 Mar 13.

Department of Otolaryngology, Head and Neck Surgery, Ehime University Graduate School of Medicine, Ehime, Japan.

Objective: Estrogen deficiency caused by bilateral ovariectomy (OVX) has been reported to lead to morphological changes in otoconia. Thus, we examined the morphological changes in the otoconial layer after OVX. We also investigated whether micro-computed tomography (µCT) is useful for the detection of morphological changes in the otoconial layer. Read More

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http://dx.doi.org/10.1016/j.anl.2020.02.013DOI Listing

Neck dissection prolongs survival in patient with stage IVC hypopharyngeal carcinoma with mixed responses to nivolumab.

Auris Nasus Larynx 2020 Mar 12. Epub 2020 Mar 12.

Department of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Tokyo, Japan.

Surgical intervention aids in maintaining quality of life in patients with recurrent metastatic head and neck carcinoma with mixed responses to nivolumab treatment. However, the mechanisms involved in these mixed responses remain unclear. Systemic chemotherapy using the EXTREME regimen was administered to the patient with hypopharyngeal carcinoma and liver metastases as well as cervical lymph node metastases. Read More

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http://dx.doi.org/10.1016/j.anl.2020.02.014DOI Listing

Increased expression of nucleophosmin is associated with the pathophysiology of chronic rhinosinusitis with nasal polyposis.

Auris Nasus Larynx 2020 Mar 2. Epub 2020 Mar 2.

Department of Pharmacology and Medicinal Toxicology Research Center, Incheon, South Korea; Hypoxia-Related Diseases Research Center, Inha University School of Medicine, Incheon, South Korea. Electronic address:

Objective: Nucleophosmin (NPM1) has been suggested to be involved in the pathophysiologic mechanism of inflammatory disorders. We measured the expression level of NPM1 in nasal polyp (NP) tissues of patients with chronic rhinosinusitis with nasal polyposis (CRSwNP). We also assessed the correlation between NPM1 expression and other parameters such as eosinophilic infiltration, inflammatory cytokines, and clinical indicators such as Lund-Mackay computed tomography (CT) score. Read More

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http://dx.doi.org/10.1016/j.anl.2020.02.010DOI Listing

Reflux finding score and reflux symptom index as potential predictors for proton pump inhibitor response in globus pharyngeus patients: A prospective study.

Auris Nasus Larynx 2020 Feb 26. Epub 2020 Feb 26.

Department of Otorhinolaryngology, Isala Clinics, Zwolle, the Netherlands.

Objective: To evaluate the patient-reported reflux symptom index (RSI) and the doctors-reported Reflux finding score (RFS) as potential predictors for proton pump inhibitor (PPI) response in patients with suspected lower pharyngeal reflux, presenting with globus pharyngeus as their primary complaint.

Methods: The research project was performed at the ENT department of Isala hospital Zwolle, the Netherlands. A before and after design was used for this single institution prospective exploratory study. Read More

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http://dx.doi.org/10.1016/j.anl.2020.02.002DOI Listing
February 2020

Bilateral vocal fold immobility: Clinical findings of ten cases and suggested treatment options.

Auris Nasus Larynx 2020 Feb 26. Epub 2020 Feb 26.

Department of Otolaryngology-Head and Neck Surgery, Yokohama City University School of Medicine, Kanagawa, Japan.

Objective: To present the clinical findings of 10 cases of bilateral vocal fold immobility (adducted type) and suggest potential treatment options.

Methods: This retrospective study included 10 patients who underwent tracheostomy for restricted airway due to bilateral vocal fold immobility of the adducted type during the period from 2007 to 2017. All 10 patients underwent unilateral laterofixation surgery with or without additional arytenoidectomy using a CO laser. Read More

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http://dx.doi.org/10.1016/j.anl.2020.02.005DOI Listing
February 2020

IgG4-related disease presenting as otogenic skull base osteomyelitis.

Auris Nasus Larynx 2020 Feb 25. Epub 2020 Feb 25.

Department of Otorhinolaryngology, Gyeongsang National University Changwon Hospital, Changwon, South Korea. Electronic address:

IgG4-related disease (IgG4-RD) is an emerging clinical disease entity characterized by tumefactive lesions at multiple sites with a dense lymphoplasmacytic infiltrate rich in IgG4+ plasma cells. Although almost any organ can be affected, IgG4-RD is most likely to involve the submandibular, lacrimal, or parotid glands in the head and neck region. However, skull base involvement presenting as otogenic skull base osteomyelitis (SBO) is rare. Read More

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http://dx.doi.org/10.1016/j.anl.2020.02.006DOI Listing
February 2020

Scar contracture prevention with local steroid injections in transoral videolaryngoscopic surgery.

Auris Nasus Larynx 2020 Feb 24. Epub 2020 Feb 24.

Department of Otolaryngology, National Defense Medical College, Saitama, Japan. Electronic address:

Objective: The aim of this study was to evaluate the efficacy and safety of local steroid injections to prevent scar contracture after transoral videolaryngoscopic surgery (TOVS) in hypopharyngeal cancer patients.

Methods: Patients were enrolled in this study if they had received a local steroid injection during TOVS and had attended an outpatient clinic after at least three months. All patients were being treated for hypopharyngeal cancer and received a single session of triamcinolone acetonide, injected using a 21-gage needle. Read More

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http://dx.doi.org/10.1016/j.anl.2020.02.007DOI Listing
February 2020

Central processing of speech sounds and non-speech sounds with similar spectral distribution: An auditory evoked potential study.

Auris Nasus Larynx 2020 Feb 24. Epub 2020 Feb 24.

Department of Otolaryngology - Head and Neck Surgery, Iwate Medical University, 19-1, Uchimaru, Morioka, Iwate, Japan.

Objective: The purpose of this study was to measure the auditory evoked potentials for speech and non-speech sounds with similar spectral distributions.

Methods: We developed two types of sounds, comprising naturally spoken vowels (natural speech sounds) and complex synthesized sounds (synthesized sounds). Natural speech sounds consisted of 5 Japanese vowels. Read More

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http://dx.doi.org/10.1016/j.anl.2020.02.008DOI Listing
February 2020

The importance of FDG-PET/CT parameters for the assessment of the immune status in advanced HNSCC.

Auris Nasus Larynx 2020 Feb 20. Epub 2020 Feb 20.

Department of Otolaryngology, Gifu University Graduate School of Medicine, Yanagido, Gifu, Gifu 501-1194, Japan.

Objective: Cancer cells secrete large amounts of lactic acid via aerobic glycolysis. We have shown that lactic acid plays an important role as a proinflammatory and immunosuppressive mediator and promotes tumor progression. Fluorine-18 fluorodeoxyglucose (FDG) uptake detected by positron emission tomography/computed tomography (PET/CT) is considered as a good indicator of aerobic glycolysis in cancer. Read More

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http://dx.doi.org/10.1016/j.anl.2020.01.002DOI Listing
February 2020

Real-time imaging of head and neck squamous cell carcinomas using confocal micro-endoscopy and applicable dye: A preliminary study.

Auris Nasus Larynx 2020 Feb 20. Epub 2020 Feb 20.

Department of Neural Regeneration and Cell Communication, Mie University Graduate School of Medicine, Edobashi 2-174, Tsu 514-8507, Japan.

Objectives: Confocal laser endomicroscopy (CLE) is a technology that enables microscopic visualization of lesions in real-time (optical biopsy) and has been successfully applied for clinical use in gastroenterology. Recently, it was also introduced for head and neck squamous cell carcinoma (HNSCC) diagnostics. We previously designed a self-made CLE, which can provide bichrome images, with topical contrast agents that are safe for use in patients. Read More

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http://dx.doi.org/10.1016/j.anl.2020.02.001DOI Listing
February 2020

Frontal sinusitis associated with orbital decompression for Graves' orbitopathy.

Auris Nasus Larynx 2020 Feb 19. Epub 2020 Feb 19.

Department of Otolaryngology - Head and Neck Surgery, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe, Hyogo, 650-0017, Japan.

Orbital decompression (OD) for Graves' orbitopathy usually includes removal of orbital medial wall. While OD occasionally cause or worsen chronic sinusitis because of the obstructed sinus drainage by prolapsed orbital fat, to date few reports have been published on the management or prevention of sinusitis associated with OD. Here, we present two patients (three sides) with newly developed and one patient (one side) with worsening obstructive frontal sinusitis following OD. Read More

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http://dx.doi.org/10.1016/j.anl.2020.01.011DOI Listing
February 2020

Implementing a flexible endoscopic evaluation of swallowing at elderly care facilities to reveal characteristics of elderly subjects who screened positive for a swallowing disorder.

Auris Nasus Larynx 2020 Feb 19. Epub 2020 Feb 19.

Department of Otolaryngology Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Japan.

Objectives: The risk of aspiration pneumonia has been reported to increase with age, especially in elderly residents of nursing homes. However, the characteristics of those with swallowing impairments at elderly care facilities have not yet been evaluated using reliable instrumental examinations. The aims of the current study were to investigate the frequency of swallowing impairment and determine the characteristics of the elderly with swallowing disorders residing at care facilities. Read More

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http://dx.doi.org/10.1016/j.anl.2020.02.004DOI Listing
February 2020

Coblation versus microdebrider-assisted turbinoplasty for endoscopic inferior turbinates reduction.

Auris Nasus Larynx 2020 Feb 18. Epub 2020 Feb 18.

Department of Otorhinolaryngology-Head & Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia. Electronic address:

Objective: Patients suffering from persistent inferior turbinates hypertrophy refractory to medical treatments require surgical intervention where the main aim is symptomatic relief without any complications. Extraturbinoplasty is one of the preferred procedures for turbinate reduction due to its efficacy in freeing up nasal space by removing the obstructing soft tissue and bone while preserving the turbinate mucosa. We sought to evaluate the effectiveness and safety of microdebrider assisted turbinoplasty (MAT) and coblation assisted turbinoplasty (CAT) performed as an extraturbinoplasty procedure. Read More

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http://dx.doi.org/10.1016/j.anl.2020.02.003DOI Listing
February 2020
1.004 Impact Factor

Randomised trial on performance, safety and clinical benefit of hyaluronic acid, hyaluronic acid plus dexpanthenol and isotonic saline nasal sprays in patients suffering from dry nose symptoms.

Auris Nasus Larynx 2020 Feb 14. Epub 2020 Feb 14.

Ursapharm Arzneimittel GmbH, Industriestraße 35, 66129 Saarbrücken, Germany. Electronic address:

Objective: Limited data exist on the clinical benefits of nasal applications for moistening the nasal mucosa. We therefore investigated the effects of hyaluronic acid, hyaluronic acid plus dexpanthenol and isotonic saline nasal sprays in patients suffering from dry nose symptoms in an otorhinolaryngological outpatient setting.

Methods: 240 patients were randomised into this prospective, three-armed clinical trial with two assessment points (baseline and 4 weeks later). Read More

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http://dx.doi.org/10.1016/j.anl.2020.01.008DOI Listing
February 2020

Quantitative three-dimensional computed tomography analysis of sinus tympani volume in temporal bones with petrous apex pneumatization.

Auris Nasus Larynx 2020 Feb 10. Epub 2020 Feb 10.

Department of ENT, Giresun University, Giresun, Turkey.

Objective: To investigate the association between sinus tympani volume and petrous apex pneumatization in this retrospective-archival temporal bone computed tomography study.

Methods: We included 46 temporal bones with pneumatized petrous apex from 26 patients and 52 temporal bones without petrous apex pneumatization from 26 other patients. Using OsiriX software for MacOS (version 3. Read More

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http://dx.doi.org/10.1016/j.anl.2020.01.009DOI Listing
February 2020

Successful transoral videolaryngoscopic surgery for leiomyoma in the base of the tongue.

Auris Nasus Larynx 2020 Feb 11. Epub 2020 Feb 11.

Department of Otolaryngology, Head and Neck Surgery, Tottori University, 36-1, Nishi-Cho, Yonago, Tottori 683-8504, Japan.

Leiomyomas are benign tumors with smooth muscle differentiation that occur most frequently in the uterine myometrium. They are uncommon in the head and neck region. We report a rare case of tongue base leiomyoma successfully resected with transoral endoscopic surgery. Read More

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http://dx.doi.org/10.1016/j.anl.2020.01.010DOI Listing
February 2020

Prediction of anterior commissure exposure of vocal folds prior to laryngeal microscopic surgery: Parameters reflecting occipito-atlanto-axial complex extension capacity.

Auris Nasus Larynx 2020 Feb 7. Epub 2020 Feb 7.

Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea. Electronic address:

Objective: The purpose of this prospective study was to identify preoperative predictors of unstable exposure of vocal folds with focus on the anterior commissure (AC) prior to Laryngeal Microscopic Surgery.

Methods And Materials: Patients were classified into four groups based on the degree of AC exposure during Laryngeal Microscopic Surgery, and for the analysis, these groups were subdivided into unstable exposure and stable exposure subgroups depending on whether external manipulation was required to achieve AC exposure. Correlation of the degree of AC exposure with demographics, physical measurements, and anatomical measurements taken using landmarks in simple radiograph were evaluated. Read More

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http://dx.doi.org/10.1016/j.anl.2020.01.006DOI Listing
February 2020