3,741 results match your criteria Auris Nasus Larynx[Journal]


Central-part laryngectomy after laryngotracheal separation to manage pharyngocutaneous fistula: A case report and retrospective analysis of 12 cases.

Auris Nasus Larynx 2022 May 11. Epub 2022 May 11.

Department of Otolaryngology-Head and Neck surgery, Asahikawa Medical University, 2-1-1-1, Midorigaoka-Higashi, Asahikawa 078-8510, Japan.

A 15-year-old girl presented with a 3-year-history of continuous outflow of saliva from a pharyngocutaneous fistula, located at 5 mm superior to her tracheal stoma. She was diagnosed with Miller-Dieker syndrome at birth. At 2 years of age, pediatric surgeons at our institution carried out laryngotracheal separation to prevent aspiration pneumonia. Read More

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The effects of dietary and physical activity interventions on tinnitus symptoms: An RCT.

Auris Nasus Larynx 2022 May 11. Epub 2022 May 11.

Otorhinolaryngology Department, Medical School, Ankara University, Ankara, Turkey.

Objective: Subjective tinnitus is defined as the perception of irregular sound at different frequencies. Although the underlying cause of tinnitus is unclear, increased body weight is known to increase tinnitus symptoms. The present study aimed to determine the effects of dietary and physical activity interventions on tinnitus symptoms. Read More

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BCOR-CCNB3 sarcoma arising in the pharynx.

Auris Nasus Larynx 2022 May 8. Epub 2022 May 8.

Department of Head and Neck Surgery, National Cancer Center Hospital, 104-0045, 5-1-1, Chuo-ku, Tokyo, Japan.

Reports on BCOR-CCNB3 sarcoma in the head and neck region are scarce, given their unknown etiology. An 18-year-old male patient presented a rapidly enlarging tumor extending from the right nasopharynx to the oropharynx. Histological examination showed a spindle cell sarcoma with BCOR-CCNB3 fusion detected by fluorescence in situ hybridization, and BCOR-CCNB3 was diagnosed. Read More

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Vocal fold fibroblasts promote angiogenesis in vocal fold leukoplakia by secreting pro-angiogenic factors.

Auris Nasus Larynx 2022 May 2. Epub 2022 May 2.

ENT Institute and Department of Otolaryngology-Head and Neck Surgery, Eye & ENT Hospital, Fudan University, 83 FenYang Road, Shanghai 200031, China. Electronic address:

Objective: Cancer-associated fibroblasts (CAFs) have been reported to play an essential role in tumor angiogenesis and progression. In this study, we aimed to investigate the impact of vocal fold leukoplakia-associated fibroblasts (VFLFs) on the angiogenesis process in vocal fold leukoplakia (VFL) and their potential secretions of proangiogenic factors.

Methods: A total of 160 lesions (86 laryngeal carcinoma, 67 vocal fold leukoplakia, 7 vocal fold polyp) were detected under narrow band imaging (NBI) mode to evaluate the relationship between pathology and intraepithelial papillary capillary loop (IPCL) grades. Read More

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Investigation of the diversity of human papillomavirus 16 variants and L1 antigenic regions relevant for the prevention of human papillomavirus-related oropharyngeal cancer in Japan.

Auris Nasus Larynx 2022 Apr 28. Epub 2022 Apr 28.

Department of Investigative Pathology, Tohoku University Graduate School of Medicine. Electronic address:

Objective: This study aimed to investigate the distribution of human papillomavirus 16 (HPV16) variants that contribute to the development of HPV-related oropharyngeal carcinoma (HPV-OPC) in the Japanese population and to evaluate genetic variations in the sequence encoding the L1 antigen region of the viral outer shell that is targeted by existing vaccines and is relevant for designing a prevention strategy to combat the exponential increase in HPV-OPC cases in Japan.

Methods: Seventy Japanese HPV-OPC patients treated at Tohoku University Hospital were included in the study. DNA was extracted from formalin-fixed, paraffin-embedded tissue samples. Read More

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Discrepancies in the caloric testing and video Head Impulse Test results in a case with bilateral lateral semicircular canal malformations.

Auris Nasus Larynx 2022 Apr 22. Epub 2022 Apr 22.

Department of Otolaryngology-Head & Neck Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

Lateral semicircular canal (LSCC) malformations represent one of the most common types of inner ear malformation. As many cases of LSCC malformations are asymptomatic, detailed vestibular functions in such cases remain unclear. We present a case with bilateral LSCC malformations for whom the function of each vestibular organ was evaluated by caloric testing, video Head Impulse Test (vHIT) and vestibular evoked myogenic potentials (VEMP). Read More

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Authors' reply to: Comment on the article by Dr. Jérôme R. LECHIEN: Laryngopharyngeal reflux, chronic rhinosinusitis and nasopharyngeal pH monitoring.

Authors:
Nam-Kyung Yeo

Auris Nasus Larynx 2022 Aug 21;49(4):735. Epub 2022 Apr 21.

Department of Otolaryngology, Gangneung Asan Hospital, University of Ulsan College of Medicine, 38, Bangdonggil, Sachunmyun, Gangneung 25440, South Korea. Electronic address:

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Patterns of velopharyngeal closure during speech in individuals with normal habitual resonance: A nasoendoscopic analysis.

Auris Nasus Larynx 2022 Apr 18. Epub 2022 Apr 18.

Medical Studies Department for Children, Faculty of Postgraduate Childhood Studies, Ain Shams University, Cairo, Egypt.

Objective: Velopharyngeal valve closure is essential for adequate speech intelligibility as well as for other activities. The variations in the contribution of different components of the velopharyngeal port walls produce different closure patterns. The aim of this cross-sectional study is to identify the prevalence of the different velopharyngeal closure patterns in Arabic-speaking individuals with no perceived hypernasality or velopharyngeal dysfunction. Read More

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Creutzfeldt-Jakob disease with dizziness initially presenting to the otolaryngology department.

Auris Nasus Larynx 2022 Apr 17. Epub 2022 Apr 17.

Department of Otorhinolaryngology, Juntendo University Faculty of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo, 113-8421 Japan.

Creutzfeldt-Jakob disease is a fatal transmissible prion disease of the central nervous system. Dizziness as an initial manifestation of Creutzfeldt-Jakob disease is rare. However, patients with Creutzfeldt-Jakob disease and dizziness may initially visit the otolaryngology department, but this is uncommon. Read More

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Recent progress in endoscopic skull base surgery: Functional preservation and multiportal approaches.

Auris Nasus Larynx 2022 Apr 16. Epub 2022 Apr 16.

Department of Otolaryngology, Head and Neck Surgery, Graduate School of Medicine, Kyoto University, 54 Kawaharacho, Shogoin, Sakyoku, Kyoto 606-8507, Japan. Electronic address:

Over the past couple of decades, endoscopic skull base surgery (ESBS) has significantly evolved and is applied to a broad range of skull base pathologies, including sinonasal malignancies. Recent studies have demonstrated remarkable progress of ESBS in complete resection with low morbidity and extension of its application to larger and more complex lesions. In this review, we focus on the evolution of functional preservation and multiportal approaches. Read More

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Comment on: COVID-19 presenting as acute epiglottitis: A case report and literature review.

Auris Nasus Larynx 2022 Apr 11. Epub 2022 Apr 11.

Department of Emergency Medicine, Far Eastern Memorial Hospital, 21, Section 2, Nan Ya South Road, New Taipei City, Taiwan. Electronic address:

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The characteristics of dysphagia and the incidence of pneumonia in Myotonic dystrophy type 1 patients especially concerning swallowing function evaluated by endoscopy.

Auris Nasus Larynx 2022 Apr 12. Epub 2022 Apr 12.

Department of Otolaryngology and Head and Neck Surgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, 980-8574, Japan.

Objective: The objectives of the study were to clarify the characteristics of dysphagia and the incidence of pneumonia in Myotonic dystrophy type 1 (DM1) patients, and to investigate the relationship between the development of pneumonia and the DM1 patient's background, especially concerning swallowing function evaluated by endoscopy.

Methods: The subjects were 88 DM1 patients who underwent swallowing function evaluation. The severity of disease in DM1patients was assessed based on the muscular impairment rating scale (MIRS), and the number of CTG repeats. Read More

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Hsa_circ_0081534 facilitates malignant phenotypes by sequestering miR-874-3p and upregulating FMNL3 in nasopharyngeal carcinoma.

Auris Nasus Larynx 2022 Apr 12. Epub 2022 Apr 12.

Department of Otorhinolaryngology, Dongguan People's Hospital, Guangdong, 523059 China.

Objective: Circular RNAs (circRNAs) are connected to nasopharyngeal carcinoma (NPC) development and progression. CircRNA hsa_circ_0081534 (circ_0081534) has been reported to be associated with NPC progression, but its underlying regulatory mechanisms are largely unknown. Thus, the study aims to investigate the mechanism by which circ_0081534 regulates NPC progression. Read More

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Analysis of various defects and reconstructive methods after invasive thyroid carcinoma resection.

Auris Nasus Larynx 2022 Apr 13. Epub 2022 Apr 13.

Department of Plastic and Reconstructive Surgery, Tokyo Women's Medical University, Japan.

Objective: The thyroid gland adjoins the trachea, pharynx, esophagus, carotid artery and cervical skin. Most thyroid carcinomas have been treated at lower stages; however, in some cases the carcinomas have invaded the surrounding organs. After resecting invasive thyroid carcinomas, the defects vary depending on the invasion area and organs affected; subsequent reconstructive methods vary depending on the size of defect and its components. Read More

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Laryngopharyngeal reflux, chronic rhinosinusitis and Nasopharyngeal pH monitoring.

Auris Nasus Larynx 2022 Aug 9;49(4):733-734. Epub 2022 Apr 9.

Department of Otorhinolaryngology-Head and Neck Surgery, American University of Beirut Medical Center, Beirut, Lebanon.

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Use of transoral carbon dioxide laser for supraglottic web from caustic ingestion in a 13 year old.

Auris Nasus Larynx 2022 Apr 4. Epub 2022 Apr 4.

Department of Otorhinolaryngology-Head and Neck Surgery, University of the Philippines-Philippine General Hospital, Taft Avenue, Ermita 1000, Manila, Philippines.

A 13 year old male was referred to the Department of Otorhinolaryngology due to unsuccessful decannulation. At 2 years of age, patient accidentally ingested a caustic liquid alkali and underwent emergency tracheostomy, exploratory laparotomy, and tube gastrectomy. 11 years after, patient was seen at the outpatient department for decannulation. Read More

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The efficacy and safety of intrathecal fluorescein in endoscopic cerebrospinal fluid leak repair -a systematic review.

Auris Nasus Larynx 2022 Apr 4. Epub 2022 Apr 4.

Department of Otorhinolaryngology, Queen Elizabeth Hospital, Birmingham, B15 2TH, United Kingdom.

Background: Effective management of cerebrospinal fluid (CSF) leaks can reduce significant associated morbidity. Intrathecal fluorescein (IF) may be a valuable intra-operative adjunct to localise leak sites. Recent reports have demonstrated low doses of IF to be safe, however, no internationally accepted dose of IF has been agreed. Read More

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Benign paroxysmal positional vertigo.

Auris Nasus Larynx 2022 Apr 3. Epub 2022 Apr 3.

Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.

Benign paroxysmal positional vertigo (BPPV) is characterized by positional vertigo (brief attacks of rotatory vertigo triggered by head position changes in the direction of gravity) and is the most common peripheral cause of vertigo. There are two types of BPPV pathophysiology: canalolithiasis and cupulolithiasis. In canalolithiasis, otoconial debris is detached from the otolithic membrane and floats freely within the endolymph of the canal. Read More

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Dysphagia in Parkinson's disease: Pharyngeal manometry and fiberoptic endoscopic evaluation.

Auris Nasus Larynx 2022 Mar 31. Epub 2022 Mar 31.

Gastroenterology Unit, University of Pisa, Pisa, Italy.

Objective: Dysphagia is a common symptom in Parkinson's disease (PD) and it represents a negative prognostic factor because of its complications. This study is to evaluate pharyngeal dysphagia for boluses of various consistencies with Fiberoptic Endoscopic Evaluation of Swallowing (FEES) and Pharyngeal High-Resolution Manometry (PHRM) in a group of PD patients, making a comparison between the information provided by the two exams.

Methods: Group of 20 patients affected by PD was selected and initially subjected to a qualitative evaluation of the swallowing performing FEES. Read More

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Improved diagnostic accuracy for pediatric obstructive sleep apnea using an out-of-center sleep test.

Auris Nasus Larynx 2022 Mar 28. Epub 2022 Mar 28.

Department of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan.

Objective: Polysomnography (PSG) is considered the gold standard for diagnosing obstructive sleep apnea syndrome (OSA) in children. However, many hospitals do not carry out PSG evaluations, and use out-of-center sleep test (OCST) devices for diagnosis instead. The aim of this study was to confirm the reliability of OCSTs for the diagnosis of pediatric OSA. Read More

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Ultrasonography for masses of the pharynx and larynx and assessment of laryngeal squamous cell carcinoma.

Auris Nasus Larynx 2022 Mar 27. Epub 2022 Mar 27.

Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyungpook National University, Daegu, Korea.

Objective: To evaluate the ultrasonography (US) characteristics of pharyngeal/laryngeal masses and the role of US in the assessment of laryngeal squamous cell carcinoma (LSCC).

Methods: This study enrolled patients who underwent US for evaluation of pharyngeal/laryngeal masses between 2018 and 2021. Characteristics of pharyngeal/laryngeal masses and subsite invasion in cases of LSCC were evaluated using US. Read More

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Is elective neck dissection necessary for patients with cT3-4N0 parotid gland cancer?

Auris Nasus Larynx 2022 Mar 26. Epub 2022 Mar 26.

Department of Head and Neck Surgery, National Cancer Center Hospital East, Chiba, Japan.

Objective: Management of the cervical lymph nodes in patients with cT3-4N0 parotid gland cancer (PGC) has been controversial. This study investigated the need for elective neck dissection (END) in patients with cT3-4N0 PGC.

Methods: We retrospectively examined cervical lymph node metastasis, overall survival (OS), and disease-free survival (DFS) rates in 40 patients with cT3-4N0 PGC according to whether or not END was performed. Read More

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Wideband acoustic immittance in superior semicircular canal dehiscence.

Auris Nasus Larynx 2022 Mar 26. Epub 2022 Mar 26.

Department of Rehabilitation Sciences, Ghent University, Belgium.

Objective: The apparent effect of superior semicircular canal dehiscence (SSCD) on middle ear- and cochlear impedance has led researchers to investigate the use of wideband acoustic immittance as a screening tool when SSCD is suspected. The purpose of the study was to describe the absorbance characteristics and tympanometric values of ears with confirmed SSCD measured at tympanometric peak pressure (TPP) and at ambient pressure.

Methods: Wideband Acoustic Immittance was performed at ambient pressure and at TPP on ten participants (12 ears) with confirmed SSCD, as well as on an age- and gender matched control group (12 ears). Read More

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Comparative evaluation of temporal subtraction computed tomography and non-echoplanar diffusion-weighted imaging for the mastoid extension of middle ear cholesteatoma.

Auris Nasus Larynx 2022 Mar 24. Epub 2022 Mar 24.

Department of Radiology, The Jikei University School of Medicine, 3-25-8 Nishi-Shimbashi, Minato-ku, Tokyo 105-8461, Japan.

Objective: Preoperative imaging assessment influences the decision to perform mastoidectomy for the mastoid extension of middle ear cholesteatoma. This study compared the performance of temporal subtraction CT (TSCT) and non-echoplanar diffusion-weighted imaging (non-EP DWI) in evaluating such mastoid extensions.

Methods: We retrospectively evaluated 239 consecutive patients with surgically proven middle ear cholesteatoma between April 2016 and April 2021. Read More

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Swallowing computed tomography and virtual reality as novel imaging modalities for the diagnosis of clicking larynx: Two case reports.

Auris Nasus Larynx 2022 Mar 24. Epub 2022 Mar 24.

Department of Otolaryngology and Head and Neck Surgery, Faculty of Medicine, the University of Tokyo, Tokyo, Japan.

Globus sensation and pain causes are difficult to identify by conventional examination methods. With technology advances, new imaging methods including swallowing computed tomography (CT) and virtual reality (VR) have emerged and are contributing to definite diagnoses. We report two cases of cervical discomfort diagnosed as clicking larynx using swallowing CT/VR . Read More

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Human papillomavirus-related multiphenotypic sinonasal carcinoma: A report of two patients and review of the literature.

Auris Nasus Larynx 2022 Mar 24. Epub 2022 Mar 24.

Department of Otolaryngology-Head and Neck Surgery, Graduate School of Medicine, Kumamoto University, Kumamoto, Japan.

Human papillomavirus (HPV)-related multiphenotypic sinonasal carcinoma (HMSC) is a recently described sinonasal tract tumor that is associated with high-risk HPV subtype infection. Despite histological features that are suggestive of a high-grade malignant tumor, the prognosis of HMSC is relatively good; however, the clinical features of this tumor are poorly understood. Here, we describe two patients with HMSC. Read More

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Pharmacotherapy focusing on for the management of otitis media with effusion in children: Systematic review and meta-analysis.

Auris Nasus Larynx 2022 Mar 24. Epub 2022 Mar 24.

Department of Otorhinolaryngology, Showa University School of Medicine.

Objective: To examine the evidence for treating children with otitis media with effusion with pharmacotherapy.

Data Sources: For the systematic review, data were retrieved from PubMed, Cochrane database, and the Japan Medical Abstracts Society Database (1st January 1995 through 31th May 2019).

Study Selection: Articles addressing pharmacotherapy for the management of otitis media with effusion in children were selected in English. Read More

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Effect of treatments for head and neck cancer on sinus shadow on computed tomography.

Auris Nasus Larynx 2022 Mar 24. Epub 2022 Mar 24.

Department of Otolaryngology, Head and Neck Surgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.

Objective: Head and neck surgeries may cause changes in the nasal airflow, and radiotherapy irreversibly damages paranasal sinus epithelial cells. Some chemotherapeutic drugs have been reported to negatively affect airway ciliary activity in mice, and chronic rhinosinusitis could be an adverse effect of head and neck cancer (HNC) treatment. To evaluate whether HNC treatment is a risk factor for developing sinonasal mucosal thickening that may reflect paranasal sinus inflammation, we compared pre- and post-treatment paranasal sinus computed tomography (CT) images of patients treated for HNC at a single university hospital. Read More

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Objective measurement of HINTS (Head Impulse, Nystagmus, Test of Skew) in peripheral vestibulopathy.

Auris Nasus Larynx 2022 Mar 23. Epub 2022 Mar 23.

Department of Otorhinolaryngology & Head and Neck Surgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam-si, Republic of Korea. Electronic address:

Objective: To evaluate how often the positive sign of HINTS (Head-Impulse, Gaze Evoked Nystagmus, Test of Skew) appears in patients with acute peripheral vestibular lesion, HINTS findings were quantitatively measured and analyzed in patients with peripheral vestibulopathy accompanying spontaneous nystagmus.

Methods: HINTS was evaluated in 14 vertigo patients with spontaneous nystagmus. Horizontal vestibulo-ocular reflex (VOR) gain was measured using the video head impulse test (vHIT). Read More

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Application of a strip design to monitor the viability of buried radial forearm free flap in East Asians: A case series study.

Auris Nasus Larynx 2022 Mar 20. Epub 2022 Mar 20.

Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University, Daehakro 101, Jongno-gu, Seoul 03080, South Korea. Electronic address:

Objectives: The objectives of this study were to evaluate the reliability of a strip design as a monitoring flap in buried flap and to investigate whether strip design of radial forearm free flap (RFFF) could affect donor site morbidity in East Asian.

Methods: Patients with externalized flap in buried RFFF were consecutively included in this study. For cases with mucosal defect repair, a skin strip with a 1. Read More

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