Brain Connect 2021 May 12. Epub 2021 May 12.
Harvard Medical School, 1811, Psychiatry and Neurology, 100 1st Avenue, suite 101, Charlestown, Boston, Massachusetts, United States, 02129;
Background: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is characterized by leukoencephalopathy leading to cognitive impairment. Subtle cognitive deficits can be observed early in the course of the disease, prior to the occurrence of the first stroke. Therefore, markers that can predict disease progression at this early stage, when interventions are likely to alter disease course, are needed. Read More