688 results match your criteria Augmentation Cystoplasty

Management of neurogenic bladder dysfunction in children update and recommendations on medical treatment.

Int Braz J Urol 2021 Feb 28;47. Epub 2021 Feb 28.

Service of Urology, Italian Hospital, Buenos Aires, Argentina.

Introduction: Defective closure of the neural tube affects different systems and generates sequelae, such as neurogenic bladder (NB). Myelomeningocele (MMC) represents the most frequent and most severe cause of NB in children. Damage of the renal parenchyma in children with NB acquired in postnatal stages is preventable given adequate evaluation, follow-up and proactive management. Read More

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February 2021

Complication profile of augmentation cystoplasty in contemporary paediatric urology: a 20-year review.

ANZ J Surg 2021 Apr 12. Epub 2021 Apr 12.

Department of Paediatric Urology, Royal Children's Hospital, Melbourne, Victoria, Australia.

Background: The aim of this study was to describe the complication profile of augmentation cystoplasty in contemporary paediatric urology as well as its effect on bladder metrics.

Methods: Consecutive operative cases were retrospectively reviewed at a single institution over 20 years (1999-2019). Short- and long-term outcomes and complications following augmentation cystoplasty were defined. Read More

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The Effect of Sacral Neuromodulation in Ambulatory Spina Bifida Patients with Neurogenic Bladder and Bowel Dysfunction.

Urology 2021 Feb 6. Epub 2021 Feb 6.

Department of Urology, China Rehabilitation Research Center, Beijing China; Department of Urology, Capital Medical University, Beijing China.

Objective: To assess the effect of sacral neuromodulation (SNM) in ambulatory spina bifida patients with neurogenic bladder and bowel dysfunction.

Materials And Methods: We retrospectively reviewed the records of 29 ambulatory spina bifida patients with neurogenic bladder and bowel dysfunction who underwent SNM testing from July 2012 to January 2020. Clinical data and video-urodynamic parameters were collected and compared using the t-test and the chi-square test. Read More

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February 2021

Paediatric cystolitholapaxy using mini PCNL-kit through the Mitrofanoff stoma.

Ann Med Surg (Lond) 2021 Feb 15;62:88-91. Epub 2021 Jan 15.

Department of Urology, Tahar Sfar Mahdia, 5100, Tunisia.

Bladder stones are a common complication after augmentation cystoplasty and urinary diversion. However, the treatment of recurrent cystolithiasis in neuropathic children remains a real challenge for urologists and open procedures may be associated with significant morbidity. Currently, mini-invasive management options are available in the therapeutic armamentarium. Read More

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February 2021

Long-term survival after radical cystectomy and mesenteric lymph node dissection for squamous cell carcinoma arising from augmented bladder with lymph node metastasis: a case report.

Int Cancer Conf J 2021 Jan 1;10(1):20-23. Epub 2020 Sep 1.

Department of Urology, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo, 113-8519 Japan.

Surgical resection is commonly performed for augmented bladder cancer, yet an optimal treatment strategy for augmented bladder cancer with lymph node metastasis has not been established. Here, we report a case that achieved 7 years of survival after radical cystectomy and mesenteric lymph node dissection for squamous cell carcinoma arising from augmented bladder with lymph node metastasis. Extended surgery could be a useful treatment option for locally advanced augmented bladder cancer including mesenteric lymph node metastasis. Read More

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January 2021

Clinical outcomes after increasing bladder outlet resistance without augmentation cystoplasty in neurogenic bladder.

J Pediatr Urol 2021 04 28;17(2):235.e1-235.e7. Epub 2020 Nov 28.

Department of Urology, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA. Electronic address:

Introduction: Patients with neurogenic bladder (NGB) and urinary incontinence (UI) due to low bladder outlet resistance may require bladder neck procedures (BNPs) to achieve continence. These patients may also have reduced bladder capacity and or elevated detrusor storage pressures that require augmentation cystoplasty (AC). AC is not without complications that include risks for bladder rupture, urolithiasis, urinary tract infections and metabolic issues. Read More

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Procyanidins-crosslinked small intestine submucosa: A bladder patch promotes smooth muscle regeneration and bladder function restoration in a rabbit model.

Bioact Mater 2021 Jun 6;6(6):1827-1838. Epub 2020 Dec 6.

Laboratory of Stem Cell and Tissue Engineering, Orthopedic Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, Sichuan, China.

Currently the standard surgical treatment for bladder defects is augmentation cystoplasty with autologous tissues, which has many side effects. Biomaterials such as small intestine submucosa (SIS) can provide an alternative scaffold for the repair as bladder patches. Previous studies have shown that SIS could enhance the capacity and compliance of the bladder, but its application is hindered by issues like limited smooth muscle regeneration and stone formation since the fast degradation and poor mechanical properties of the SIS. Read More

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[Treatment for refractory non-neurogenic overactive bladder].

X Gamé V Phé

Prog Urol 2020 Nov;30(14):920-930

Service d'urologie, hôpital Pitié-Salpêtrière, Sorbonne université, AP-HP, Paris, France.

Introduction: The aim was to synthesize current knowledge on refractory overactive bladder treatments.

Method: A systematic literature review based on PubMed, Embase and Google Scholar was conducted in July 2020.

Results: Today, refractory overactive bladder treatment includes tibial nerve stimulation, whether percutaneously or transcutaneously, sacral neuromodulation, and botulinum toxin A detrusor injections. Read More

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November 2020

Sexual function in adult patients who have undergone augmentation surgery in childhood: what is really important?

Int J Impot Res 2021 Mar 10;33(2):170-177. Epub 2020 Oct 10.

Department of Pediatric Urology, Hospital of the Sisters of Charity, Linz, Austria.

Problems relating to the development of a healthy approach to sex and intimacy during puberty, after augmentation cystoplasty, are scarcely discussed in literature. Therefore, this may suggest that such issues are insufficiently addressed by pediatric urologists. We gathered four experts in the field as well as an experienced leader of a patient group and mother of a girl with spina bifida and asked questions relevant to the following areas of care: (a) diversion, urinary incontinence, and sexual life; (b) impact of a stoma on body image perception and self-esteem; (c) specific female concerns with regard to fertility and recurrent urinary infections; (d) specific male concerns on anejaculation and erectile dysfunction. Read More

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Robot-assisted Supratrigonal Cystectomy and Augmentation Cystoplasty with Totally Intracorporeal Reconstruction in Neurourological Patients: Technique Description and Preliminary Results.

Eur Urol 2020 Oct 2. Epub 2020 Oct 2.

Department of Urology, Médecine Sorbonne Université, Pitié-Salpêtrière Academic Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.

Background: Augmentation cystoplasty as a third-line therapy for neurogenic detrusor overactivity performed by an open approach has long been studied. Few laparoscopic and robot-assisted series have been reported.

Objective: To evaluate the feasibility, safety, and functional outcomes of completely intracorporeal robot-assisted supratrigonal cystectomy and augmentation cystoplasty (RASCAC) in patients with refractory neurogenic detrusor overactivity. Read More

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October 2020

Invasive poorly differentiated adenocarcinoma of the bladder following augmentation cystoplasty: a multi-institutional clinicopathological study.

Pathology 2021 Feb 17;53(2):214-219. Epub 2020 Sep 17.

Department of Pathology, Emory University School of Medicine, Atlanta, GA, USA; Department of Urology, Emory University School of Medicine, Atlanta, GA, USA; Winship Cancer Institute of Emory University, Atlanta, GA, USA; Department of Pathology, Veterans Affairs Medical Center, Decatur, GA, USA. Electronic address:

Augmentation cystoplasty is a surgical procedure used in the management of patients with neurogenic bladder. This procedure involves anastomosis of the bladder with gastrointestinal grafts, including portions of ileum, colon, or stomach. A rare but important complication of augmentation cystoplasty is the development of malignancy. Read More

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February 2021

Surgical outcomes of bladder augmentation: A comparison of three different augmentation procedures.

World J Clin Cases 2020 Aug;8(15):3240-3248

Department of Pediatric Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan 250012, Shandong Province, China.

Background: Augmentation cystoplasty is indispensable in many pediatric diseases, especially neurogenic bladder. Various methods and materials are used to augment the bladder, and these methods are associated with different shortcomings and complications.

Aim: The present study reported the mid-term outcomes of patients undergoing various bladder augmentation procedures in a single institution, and assessed whether seromuscular cystoplasty lined with urothelium (SCLU) provided better urodynamic results than auto-augmentation (AA). Read More

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[Metastase from lobular breast carcinoma on the ileal patch of augmentation].

Rev Med Liege 2020 Jul;75(7-8):537-540

Service d'Urologie, CHU Liège, Belgique.

Patients treated with bladder augmentation have a higher risk of developing bladder cancer than the general population. In these patients, tumours are most frequently primary bladder cancers. Metastasis in an augmentation cystoplasty is extremely rare and here we describe the first case of metastasis from lobular breast carcinoma in an ileal patch. Read More

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Villous Adenoma Arising in the Urethra of a Female with Bladder Augmentation History: A Case Report and Review of the Literature.

Turk Patoloji Derg 2021 ;37(2):161-166

Department of Pathology, Amasya University, School of Medicine, AMASYA, TURKEY.

Villous adenomas (VAs) in the female urethra are rare with only seven cases in the English literature to our knowledge. In patients with bladder augmentation cystoplasty, the neoplasia development risk increases and most of these develop in the neobladder or anastomosis line. Only two cases of VA developing from the native bladder mucosa have been reported. Read More

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January 2021

Course of Urological Problems in Children with Spinal Dysraphism: Long-Term Follow-Up Results.

Pediatr Neurosurg 2020 17;55(2):101-105. Epub 2020 Jul 17.

Department of Neurosurgery, Bahcesehir University School of Medicine, Istanbul, Turkey.

Background/aims: We aimed to evaluate the course of urinary problems in children with spinal dysraphism.

Methods: This multicenter study evaluated data on pediatric patients diagnosed with spinal dysraphism between 2010 and 2019. The neurological and urological conditions of the patients were examined retrospectively. Read More

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The efficacy of onabotulinumtoxinA in patients with previous failed augmentation cystoplasty: Cohort series and literature review.

Neurourol Urodyn 2020 08 22;39(6):1831-1836. Epub 2020 Jun 22.

Department of Urology, University College London Hospital, London, UK.

Aims: To investigate the role of onabotulinumtoxinA (BTX-A) injections in patients with failed augmentation cystoplasty for neuropathic or idiopathic detrusor overactivity (NDO or IDO).

Methods: A retrospective review of all cystoplasty patients who underwent onabotulinumtoxinA injection at a tertiary center between 2008 and 2019 was performed. Details including indications and time from cystoplasty, video-urodynamic parameters, onabotulinumtoxinA dose, and clinical outcomes were analyzed. Read More

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Refractory bladder dysfunction: A multi-institutional experience with intravesical botulinum toxin-a injection in adult patients who underwent previous augmentation cystoplasty.

Turk J Urol 2020 Jun 5. Epub 2020 Jun 5.

Department of Urology, Houston Methodist Hospital, Houston, USA.

Objective: Augmentation cystoplasty is a treatment option for neurogenic lower urinary tract dysfunction as well as severe, refractory, complicated idiopathic overactive bladder. In some patients, symptoms may persist or recur postoperatively, and there is little guidance on management in this setting. In this study, we reviewed the use of intravesical onabotulinum toxin type A (BTX-A) in patients who had undergone augmentation cystoplasty. Read More

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Contemporary multicenter outcomes of continent cutaneous ileocecocystoplasty in the adult population over a 10-year period: A Neurogenic Bladder Research Group study.

Neurourol Urodyn 2020 08 7;39(6):1771-1780. Epub 2020 Jun 7.

Division of Urology, University of Utah, Salt Lake City, Utah.

Aims: Evidence is sparse on the long-term outcomes of continent cutaneous ileocecocystoplasty (CCIC). We hypothesized that obesity, laparoscopic/robotic approach, and concomitant surgeries would affect morbidity after CCIC and aimed to evaluate the outcomes of CCIC in adults in a multicenter contemporary study.

Methods: We retrospectively reviewed the charts of adult patients from sites in the Neurogenic Bladder Research Group undergoing CCIC (2007-2017) who had at least 6 months of follow-up. Read More

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Utilization of Augmentation Cystoplasty for Myelomeningocele Patients Remained Stable Over the Past Decade.

Urology 2020 Aug 30;142:195-199. Epub 2020 Apr 30.

Division of Urology, Nationwide Children's Hospital, Columbus, OH.

Objective: To understand the utilization of augmentation cystoplasty (AC) for the management of neurogenic bladder in children with myelomeningocele (MMC). AC carries considerable risk. To mitigate this, recent studies have emphasized alternatives to AC, but it is unknown if these interventions have resulted in fewer ACs being performed. Read More

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The basics of transition in congenital lifelong urology.

World J Urol 2020 Feb 19. Epub 2020 Feb 19.

Department of Pediatric Urology, Riley Children Hospital at Indiana University Health (IHU), Indiana University School of Medicine, 705 Riley Hospital Drive, ROC Suite #4230, Indianapolis, IN, 46202, USA.

Purpose: Transition in urology is defined by the process that allows an adolescent or a young adult with a congenital or acquired urogenital anomaly to assume increasing responsibility for their own health care and to become the primary decision maker in their care.

Methods: A review of the literature regarding transitional care for lifelong urologic congenital anomalies was performed with the aim of reporting expert opinion when data are non-existent. This review focuses on special considerations for adolescents and young adults with spina bifida, bladder exstrophy, anorectal malformations and differences of sexual development. Read More

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February 2020

Current management of refractory overactive bladder.

Low Urin Tract Symptoms 2020 May 19;12(2):109-116. Epub 2020 Feb 19.

Department of Urology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Fundation and Tzu Chi University, Hualien, Taiwan.

Overactive bladder (OAB) is a common condition affecting one-sixth to one-fifth of the global population. The treatment of refractory OAB remains a challenge for urologists. Current treatment options include the use of combination therapy with antimuscarinic agents and beta-3 adrenoceptor agonists, and treating underlying curable disorders. Read More

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Continent cutaneous ileocecal cystoplasty in the treatment of refractory bladder neck contracture and urinary incontinence after prostate cancer treatment.

Can J Urol 2020 02;27(1):10093-10098

Department of Surgery, Division of Urology and Urologic Oncology, City of Hope National Medical Center, Duarte, California, USA.

Introduction: To assess the use, complications, and outcomes of continent cutaneous ileocecal cystoplasty (CCIC) for the management of refractory bladder neck contractures and/or urinary incontinence after prostate cancer therapy.

Materials And Methods: An institutional review board approved database was reviewed for patients who underwent CCIC from January 1, 2003 to December 31, 2018. Preoperative, perioperative and postoperative factors were assessed, including complications and outcomes. Read More

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February 2020

Transureteroureterostomy as an adjunctive antireflux procedure in children undergoing bladder augmentation for neurogenic bladder with major reflux.

J Pediatr Urol 2020 Apr 19;16(2):190.e1-190.e6. Epub 2019 Dec 19.

Department of Paediatric Surgery, Christian Medical College, Vellore, India; Department of Paediatric Surgery, PSG Medical College and Hospital, Coimbatore, India.

Introduction: Transureteroureterostomy (TUU) provides urinary drainage of both renal systems to the bladder via a single ureter and is useful in selected situations of complex urological reconstructions. Herein we discuss its use, advantages and complications in children with neurogenic bladders and high-grade (4/5) reflux who have undergone augmentation cystoplasty.

Patients And Methods: Children with neurogenic bladder complicated by unilateral or bilateral high-grade vesicoureteric reflux (VUR), who underwent TUU along with augmentation cystoplasty (BA), were selected from two institutions. Read More

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Featuring: urodynamic and imaging findings in infants with myelomeningocele may predict need for future augmentation cystoplasty.

J Pediatr Urol 2019 12;15(6):595-597

Department of Urology, University of Florida College of Medicine, Gainesville, FL, USA. Electronic address:

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December 2019

Long-term urological outcomes of spinal lipoma after prophylactic untethering in infancy: real-world outcomes by lipoma anatomy.

Spinal Cord 2020 Apr 26;58(4):490-495. Epub 2019 Nov 26.

Department of Urology, Kanagawa Children's Medical Center, Yokohama, Japan.

Study Design: Cohort study.

Objectives: Long-term urological outcomes in patients with spinal lipoma after prophylactic tethered cord release (TCR) in infancy were investigated.

Setting: Children's hospital in Yokohama, Japan. Read More

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Mucosectomy disrupting the enteric nervous system causes contraction and shrinkage of gastrointestinal flaps: potential implications for augmentation cystoplasty.

J Pediatr Urol 2020 02 18;16(1):20-26. Epub 2019 Sep 18.

Institute of Surgical Research, University of Szeged, Pulz U.1., Szeged, H-6724, Hungary; Department of Paediatric Urology, The Royal Manchester Children's Hospital, Oxford Road, Manchester, M13 9WL, United Kingdom. Electronic address:

Introduction: Augmenting the bladder with a seromuscular gastrointestinal flap is a promising alternative approach aiming for a mucus-free bladder augmentation; however, the contraction (shrinkage) of the flaps remains a major concern. Enteric nervous system (ENS) abnormalities cause a failure of relaxation of the intestinal muscle layers in motility disorders such as Hirschsprung's disease and intestinal neuronal dysplasia. In mammals, the submucosal enteric nervous plexus contains nitrergic inhibitory motor neurons responsible for muscle relaxation. Read More

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February 2020

Re-evaluation of histological findings after colocystoplasty and gastrocystoplasty.

J Pediatr Urol 2019 Dec 15;15(6):651.e1-651.e8. Epub 2019 Oct 15.

Department of Paediatrics, Division of Paediatric Surgery, University of Pecs, Medical School, Hungary.

Introduction: The potential of malignant transformation and its risk factors after bladder augmentation performed in childhood are still unknown. The necessity of surveillance cystoscopies and biopsies has been questioned in the past decade.

Objective: In a previous study, the authors did not detect any malignancy after colocystoplasty (CCP) or gastrocystoplasty (GCP) during the short-term follow-up, however, various alterations of the mucosa were found. Read More

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December 2019

Long-term follow-up of neurogenic bladder patients after bladder augmentation with small intestinal submucosa.

World J Urol 2020 Sep 11;38(9):2279-2288. Epub 2019 Nov 11.

Department of Urology, Fengtai District, China Rehabilitation Research Center, 10 JiaomenBeilu, Beijing, 100068, China.

Purpose: To evaluate the long-term effect of using small intestinal submucosa (SIS) for bladder augmentation in patients with neurogenic bladder.

Materials And Methods: A total of 15 patients (age range 14-65 years; mean age 29.6 years) were enrolled in our study. Read More

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September 2020

Urodynamic and imaging findings in infants with myelomeningocele may predict need for future augmentation cystoplasty.

J Pediatr Urol 2019 Dec 21;15(6):644.e1-644.e5. Epub 2019 Sep 21.

University of Michigan, Department of Urology, 1500 E Medical Center Drive, SPC 5330, Ann Arbor, MI, USA.

Introduction: Urologic issues are persistent and important causes of morbidity and mortality in patients with myelomeningocele. Classically, patients with elevated bladder pressures despite adherence to clean intermittent catheterization (CIC) and pharmacotherapy undergo augmentation cystoplasty (AC). Currently, there is little understanding of which infants are more likely to require AC later. Read More

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December 2019