982 results match your criteria Audiology And Neuro-otology[Journal]


Comparison of Place-versus-Pitch Mismatch between a Perimodiolar and Lateral Wall Cochlear Implant Electrode Array in Patients with Single-Sided Deafness and a Cochlear Implant.

Audiol Neurootol 2019 Apr 17;24(1):38-48. Epub 2019 Apr 17.

Department of Otorhinolaryngology and Head and Neck Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.

Background: In electric-acoustic pitch matching experiments in patients with single-sided deafness and a cochlear implant, the observed "mismatch" between perceived pitch and predicted pitch, based on the amended Greenwood frequency map, ranges from -1 to -2 octaves. It is unknown if and how this mismatch differs for perimodiolar versus lateral wall electrode arrays.

Objectives: We aimed to investigate if the type of electrode array design is of influence on the electric-acoustic pitch match. Read More

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http://dx.doi.org/10.1159/000499154DOI Listing

Speech Recognition of Cochlear Implant Users Inside a Noisy Helicopter Environment.

Audiol Neurootol 2019 Apr 5;24(1):32-37. Epub 2019 Apr 5.

Department of Otorhinolaryngology, University of São Paulo School of Medicine, São Paulo, Brazil.

In this study, we tested whether the speech recognition, through radio communications, of cochlear implant (CI) users inside a noisy helicopter cockpit is adequate for safe flight.

Method: Speech recognition tests (sentences, numbers and disyllables) through a very-high-frequency radio were administered to 12 CI users in a soundproof booth, inside a helicopter with the engine turned off and turned on.

Results: In quiet environments, radio communications were impacted only for disyllable intelligibility, but in noisy situations, all tests were affected. Read More

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http://dx.doi.org/10.1159/000497031DOI Listing

Identification and Clinical Implications of a Novel MYO15A Variant in a Consanguineous Iranian Family by Targeted Exome Sequencing.

Audiol Neurootol 2019 Apr 3;24(1):25-31. Epub 2019 Apr 3.

Cellular and Molecular Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran,

Background And Objectives: Hereditary hearing loss (HL) is known by a very high genetic heterogeneity, which makes a molecular diagnosis problematic. Next-generation sequencing (NGS) is a new strategy that can overcome this problem.

Method: A comprehensive family history was obtained, and clinical evaluations and pedigree analysis were performed in the family with 3 affected members. Read More

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http://dx.doi.org/10.1159/000498843DOI Listing

Genetic Polymorphisms and Susceptibility to Sudden Sensorineural Hearing Loss: A Systematic Review.

Audiol Neurootol 2019 Mar 14;24(1):8-19. Epub 2019 Mar 14.

Department of Otolaryngology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China,

Background: Recently, genetic factors have been considered as an important risk factor for sudden sensorineural hearing loss (SSNHL). Many studies analyzed the association between SSNHL and polymorphisms. However, most of them gave inconclusive results. Read More

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http://dx.doi.org/10.1159/000497032DOI Listing
March 2019
1 Read

Inappropriate Use of the "Rosowski Criteria" and "Modified Rosowski Criteria" for Assessing the Normal Function of Human Temporal Bones.

Audiol Neurootol 2019 Mar 14;24(1):20-24. Epub 2019 Mar 14.

Institute of Translational Medicine, Birmingham, United Kingdom.

Important research by Rosowski et al. [Twenty-Seventh Meeting of the Association for Research in Otolaryngology, 2004, p. 275] has led to a standard practice by the American Society for Testing Materials [West Conshohocken: ASTM International; 2014] to assess normal function of temporal bones used in the development of novel middle ear actuators and sensors. Read More

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http://dx.doi.org/10.1159/000495131DOI Listing

Stapes Prosthesis Length: One Size Fits All?

Audiol Neurootol 2019 Feb 19;24(1):1-7. Epub 2019 Feb 19.

Department of Otolaryngology, Head and Neck Surgery, Klinikum Bielefeld, Academic Hospital: Ruhr Universität Bochum, Bielefeld, Germany,

Background: The insertion of the stapes piston into the vestibule provides the physical basis for a successful stapedotomy. In routine clinical practice, two different ways to handle prosthesis length are performed: (1) an individualized measurement of the stapes prosthesis length or (2) a standard prosthesis length for all cases.

Objective: The objective of this study was to compare both ways of handling prosthesis length and the effect of these methods on insertional prosthesis depth. Read More

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http://dx.doi.org/10.1159/000494915DOI Listing
February 2019

A Prospective Study of the Effect of Cochlear Implantation on Tinnitus.

Audiol Neurootol 2018 8;23(6):356-363. Epub 2019 Feb 8.

Department of Otorhinolaryngology and Head and Neck Surgery, University Medical Center Groningen, Groningen, The Netherlands.

Previous studies have shown diverse and sometimes even contrary results concerning the effect of cochlear implantation on tinnitus and the factors that can influence this effect. The aim of this prospective questionnaire study was to determine the effects of cochlear implantation on tinnitus and explore which factors can influence the effect of cochlear implantation on tinnitus. Forty-four of the patients implanted in our hospital returned 2 questionnaire packages, i. Read More

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http://dx.doi.org/10.1159/000495132DOI Listing
February 2019
1 Read

Cochlear Implant Users with Otosclerosis: Are Hearing and Quality of Life Outcomes Worse than in Cochlear Implant Users without Otosclerosis?

Audiol Neurootol 2018 8;23(6):345-355. Epub 2019 Feb 8.

Department of Otolaryngology, La Paz University Hospital, IdiPAZ Research Institute, Madrid, Spain,

Background: The otosclerotic process may influence the performance of the cochlear implant (CI). Difficulty in inserting the electrode array due to potential ossification of the cochlea, facial nerve stimulation, and instability of the results are potential challenges for the CI team.

Objectives: To evaluate hearing results and subjective outcomes of CI users with otosclerosis and to compare them with those of CI users without otosclerosis. Read More

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http://dx.doi.org/10.1159/000496191DOI Listing
February 2019

Toward Optimizing cVEMP: 2,000-Hz Tone Bursts Improve the Detection of Superior Canal Dehiscence.

Audiol Neurootol 2018 24;23(6):335-344. Epub 2019 Jan 24.

Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA,

Background: The cervical vestibular evoked myogenic potential (cVEMP) test measures saccular and inferior vestibular nerve function. The cVEMP can be elicited with different frequency stimuli and interpreted using a variety of metrics. Patients with superior semicircular canal dehiscence (SCD) syndrome generally have lower cVEMP thresholds and larger amplitudes, although there is overlap with healthy subjects. Read More

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https://www.karger.com/Article/FullText/493721
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http://dx.doi.org/10.1159/000493721DOI Listing
January 2019
21 Reads

Histopathology of the Inner Ear in Charcot-Marie-Tooth Syndrome Caused by a Missense Variant (p.Thr65Ala) in the MPZ Gene.

Audiol Neurootol 2018 24;23(6):326-334. Epub 2019 Jan 24.

Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA.

Charcot-Marie-Tooth (CMT) syndrome is a clinically and genetically heterogeneous group of neuropathies affecting both peripheral motor and sensory nerves. Progressive sensorineural hearing loss, vestibular abnormalities, and dysfunction of other cranial nerves have been described. This is the second case report of otopathology in a patient with CMT syndrome. Read More

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https://www.karger.com/Article/FullText/495176
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http://dx.doi.org/10.1159/000495176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421093PMC
January 2019
11 Reads

Long-Term Outcomes of Vibroplasty Coupler Implantations to Treat Mixed/Conductive Hearing Loss.

Audiol Neurootol 2018 16;23(6):316-325. Epub 2019 Jan 16.

Department of Otorhinolaryngology, Head and Neck Surgery, Medical Faculty, University of Cologne, Cologne, Germany.

Objective: To evaluate the long-term safety and performance of four different vibroplasty couplers (round window, oval window, CliP and Bell coupler) in combination with an active middle ear implant.

Methods: This was a multicentre, prospective, long-term study including 5 German hospitals. Thirty adult subjects suffering from conductive or mixed hearing loss were initially enrolled for the study, 24 of these were included in the final analysis with up to 36 months of postsurgical follow-up data. Read More

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http://dx.doi.org/10.1159/000495560DOI Listing
January 2019
2 Reads

Round Window Niche Drilling with Intratympanic Steroid Is a Salvage Therapy of Sudden Hearing Loss.

Audiol Neurootol 2018 10;23(6):309-315. Epub 2019 Jan 10.

Department of Otolaryngology, Head and Neck Surgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China,

Objective: To explore the effectiveness and safety of round window niche drilling combined with intratympanic methylprednisolone injection for the salvage treatment of sudden sensorineural hearing loss (SSNHL) and its associated tinnitus after failed primary treatment.

Method: SSNHL patients who showed a less than 10-dB improvement of pure-tone average after receiving standard systemic treatment and intratympanic steroid injection were enrolled. All included patients were randomly divided into two groups (control and study). Read More

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http://dx.doi.org/10.1159/000493086DOI Listing
January 2019
3 Reads

Measurements of Trunk Sway for Stance and Gait Tasks 2 Years after Vestibular Neurectomy.

Audiol Neurootol 2018 12;23(5):298-308. Epub 2018 Dec 12.

Department of Otorhinolaryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

The aim of this study was to investigate changes in balance control for stance and gait tasks in patients 2 years before and after vestibular neurectomy (VN) performed to alleviate intractable Meniere's disease. Amplitudes of trunk sway in roll and pitch directions were measured for stance and gait tasks in 19 patients using gyroscopes mounted at the lower-back. Measurements before VN and 2 years later were compared to those of healthy age-matched controls (HC). Read More

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http://dx.doi.org/10.1159/000494965DOI Listing
December 2018
1 Read

The Value of Unilateral CIs, CI-CROS and Bilateral CIs, with and without Beamformer Microphones, for Speech Understanding in a Simulation of a Restaurant Environment.

Audiol Neurootol 2018 11;23(5):270-276. Epub 2018 Dec 11.

Advanced Bionics, Valencia, California, USA.

Objective: Our primary aim was to determine, in a simulation of a crowded restaurant, the value to speech understanding of (i) a unilateral cochlear implant (CI), (ii) a CI plus CROS (contralateral routing of signals) aid system and (iii) bilateral CIs when tested with and without beamforming microphones.

Design: The listeners were 7 CI listeners who had used bilateral CIs for an average of 9 years. The listeners were tested with three device configurations (bilateral CI, unilateral CI + CROS, and unilateral CI), two signal processing conditions (without and with beamformers) and with speech either from +90°, -90°, or from the front. Read More

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https://www.karger.com/Article/FullText/493844
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http://dx.doi.org/10.1159/000493844DOI Listing
December 2018
1 Read

The Efficacy of Concurrent or Sequential Intravenous and Intratympanic Steroid for Idiopathic Sudden Sensorineural Hearing Loss.

Audiol Neurootol 2018 11;23(5):277-284. Epub 2018 Dec 11.

Department of Otorhinolaryngology - Head and Neck Surgery, Taipei Veterans General Hospital, Taipei, Taiwan.

Objective: The purpose of this retrospective study was to investigate the difference in treatment outcomes for patients with idiopathic sudden sensorineural hearing loss (SSNHL) undergoing concurrent or sequential intravenous (IV) and intratympanic (IT) steroid therapies.

Methods: Patients with idiopathic SSNHL admitted to Taipei Veterans Hospital from August 2011 to August 2012 were enrolled. Patients were treated with both IV dexamethasone 5 mg b. Read More

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http://dx.doi.org/10.1159/000494966DOI Listing
December 2018
2 Reads

Comparison of Pure-Tone Average Methods for Estimation of Hearing Loss Caused by Environmental Exposure to Lead and Cadmium: Does the Pure-Tone Average Method Which Uses Low-Frequency Ranges Underestimate the Actual Hearing Loss Caused by Environmental Lead and Cadmium Exposure?

Audiol Neurootol 2018 11;23(5):259-269. Epub 2018 Dec 11.

BK21 PLUS Program in Embodiment: Health-Society Interaction, Department of Public Health Sciences, Graduate School, Korea University, Seoul, Republic of Korea.

Previous studies have reported that exposure to lead and cadmium can damage the inner ear receptor, which perceives high-frequency sounds. However, few studies have used the pure-tone average (PTA), including high-frequency ranges, for the estimation of hearing loss caused by lead and cadmium exposure. We estimated hearing loss using the PTA test, in low-frequency, speech frequency, and high-frequency ranges and compared the differences in the results using 3 PTA calculation methods. Read More

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http://dx.doi.org/10.1159/000494049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425850PMC
December 2018
2 Reads

Progression of Hearing Loss in the Aging Population: Repeated Auditory Measurements in the Rotterdam Study.

Audiol Neurootol 2018 11;23(5):290-297. Epub 2018 Dec 11.

Department of Otorhinolaryngology, Head and Neck Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands.

We quantified changes in the auditory acuity of 675 aging adults (mean age 71.1 years, 52.0% female, mean follow-up 4. Read More

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http://dx.doi.org/10.1159/000492203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428155PMC
December 2018
2 Reads

Viewing Target Distance Influences the Vestibulo-Ocular Reflex Gain when Assessed Using the Video Head Impulse Test.

Audiol Neurootol 2018 11;23(5):285-289. Epub 2018 Dec 11.

Neuro-Otology Unit, Division of Brain Sciences, Charing Cross Hospital Campus, Imperial College London, London, United Kingdom,

Gaze stabilization during head movements is provided by the vestibulo-ocular reflex (VOR). Clinical assessment of this reflex is performed using the video Head Impulse Test (vHIT). To date, the influence of different fixation distances on VOR gain using the vHIT has not been explored. Read More

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http://dx.doi.org/10.1159/000493845DOI Listing
December 2018
1 Read

Dexamethasone and Dexamethasone Phosphate Entry into Perilymph Compared for Middle Ear Applications in Guinea Pigs.

Audiol Neurootol 2018 29;23(4):245-257. Epub 2018 Nov 29.

Otonomy, Inc., San Diego, California, USA.

Dexamethasone phosphate is widely used for intratympanic therapy in humans. We assessed the pharmacokinetics of dexamethasone entry into perilymph when administered as a dexamethasone phosphate solution or as a micronized dexamethasone suspension, with and without inclusion of poloxamer gel in the medium. After a 1-h application to guinea pigs, 10 independent samples of perilymph were collected from the lateral semicircular canal of each animal, allowing entry at the round window and stapes to be independently assessed. Read More

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https://www.karger.com/Article/FullText/493846
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http://dx.doi.org/10.1159/000493846DOI Listing
November 2018
2 Reads

Visual Analogue Scales as a Tool for Initial Assessment of Tinnitus Severity: Psychometric Evaluation in a Clinical Population.

Audiol Neurootol 2018 15;23(4):229-237. Epub 2018 Nov 15.

World Hearing Center, Institute of Physiology and Pathology of Hearing, Warsaw/Kajetany, Poland,

The aim of this study was to evaluate the psychometric properties of patient-reported visual analogue scale (VAS) ratings. All of the participants (100 Polish-speaking adults) completed a Tinnitus Functional Index (TFI) once and a 4-component VAS twice over a period of 3 days. Spearman's correlation coefficients between the VAS score and global TFI ranged from ρ = 0. Read More

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http://dx.doi.org/10.1159/000494021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381860PMC
November 2018
1 Read

Working Memory Function in Children with Single Side Deafness Using a Bone-Anchored Hearing Implant: A Case-Control Study.

Audiol Neurootol 2018 15;23(4):238-244. Epub 2018 Nov 15.

Cochlear Implant Unit, Children Hospital Santobono-Pausilipon, Naples, Italy.

The importance of a good hearing function to preserve memory and cognitive abilities has been shown in the adult population, but studies on the pediatric population are currently lacking. This study aims at evaluating the effects of a bone-anchored hearing implant (BAHI) on speech perception, speech processing, and memory abilities in children with single side deafness (SSD). We enrolled n = 25 children with SSD and assessed them prior to BAHI implantation, and at 1-month and 3-month follow-ups after BAHI implantation using tests of perception in silence and perception in phonemic confusion, dictation in silence and noise, and working memory and short-term memory function in conditions of silence and noise. Read More

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http://dx.doi.org/10.1159/000493722DOI Listing
November 2018
1 Read

Dynamic Postural Stability and Hearing Preservation after Cochlear Implantation.

Audiol Neurootol 2018 14;23(4):222-228. Epub 2018 Nov 14.

Department of Otorhinolaryngology-Head and Neck Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland,

Objectives: (1) To assess dynamic postural stability before and after cochlear implantation using a functional gait assessment (FGA). (2) To evaluate the correlation between loss of residual hearing and changes in dynamic postural stability after cochlear implantation.

Methods: Candidates for first-sided cochlear implantation were prospectively included. Read More

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http://dx.doi.org/10.1159/000494247DOI Listing
November 2018
1 Read

Performance with an Auditory Brainstem Implant and Contralateral Cochlear Implant in Pediatric Patients.

Audiol Neurootol 2018 2;23(4):216-221. Epub 2018 Nov 2.

Department of Otolaryngology-Head and Neck Surgery, New York University School of Medicine, New York, New York, USA.

Objective: To assess bimodal auditory performance in children with a cochlear implant (CI) and contralateral auditory brainstem implant (ABI).

Methods: This is a retrospective case review performed at a tertiary referral center. Four patients with cochlear nerve deficiency initially underwent cochlear implantation but were not benefiting from their devices and underwent ABI in the contralateral ear. Read More

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https://www.karger.com/Article/FullText/493085
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http://dx.doi.org/10.1159/000493085DOI Listing
November 2018
12 Reads

Comparison of Two Different Treatment Protocols Using Systemic and Intratympanic Steroids with and without Hyperbaric Oxygen Therapy in Patients with Severe to Profound Idiopathic Sudden Sensorineural Hearing Loss: A Randomized Controlled Trial.

Audiol Neurootol 2018 31;23(4):199-207. Epub 2018 Oct 31.

Department of Otorhinolaryngology and Biomedical Research Institute, Pusan National University Hospital, Busan, Republic of

Objectives: This study aimed to investigate the efficacy of simultaneous steroid and hyperbaric oxygen therapy (HBOT) in patients with severe to profound idiopathic sudden sensorineural hearing loss (ISSNHL), which has a poor prognosis.

Methods: Sixty patients diagnosed with severe to profound ISSNHL (≥70 dB HL) were randomly divided into two groups in a prospective controlled trial: an oral steroid + intratympanic steroid injection (ITSI) group (control group) and an oral steroid + ITSI + HBOT group (study group). Pure-tone audiometry (PTA) results and word discrimination scores (WDS) were compared between the two groups before treatment and 10 days and 1, 2, and 3 months after treatment. Read More

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https://www.karger.com/Article/FullText/493558
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http://dx.doi.org/10.1159/000493558DOI Listing
October 2018
2 Reads

The Effect of the MicroRNA-183 Family on Hair Cell-Specific Markers of Human Bone Marrow-Derived Mesenchymal Stem Cells.

Audiol Neurootol 2018 31;23(4):208-215. Epub 2018 Oct 31.

Department of Genetic and Molecular Medicine, Hamadan University of Medical Sciences, Hamadan,

Hearing loss is considered the most common sensory disorder across the world. Nowadays, a cochlear implant can be an effective treatment for patients. Moreover, it is often believed that sensorineural hearing loss in humans is caused by loss or disruption of the function of hair cells in the cochlea. Read More

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http://dx.doi.org/10.1159/000493557DOI Listing
October 2018
1.852 Impact Factor

Binaural Perception in Single-Sided Deaf Cochlear Implant Users with Unrestricted or Restricted Acoustic Hearing in the Non-Implanted Ear.

Audiol Neurootol 2018 23;23(3):187-197. Epub 2018 Oct 23.

CHRU de Tours, Service ORL et Chirurgie Cervico-Faciale, Tours,

Cochlear implantation (CI) can benefit patients with single-sided deafness (SSD) in terms of sound localization, speech understanding in noise, tinnitus severity, and quality of life (QoL). In previous studies, CI outcomes have been largely reported for SSD patients with normal "unrestricted" hearing in the contralateral ear. However, SSD patients may often have some degree of hearing loss in the contralateral ear ("restricted" acoustic hearing). Read More

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http://dx.doi.org/10.1159/000490879DOI Listing
October 2018

The Effects of Gusher-Related Intracochlear Pressure Changes on Hearing Preservation in Cochlear Implantation: A Comparative Series.

Audiol Neurootol 2018 10;23(3):181-186. Epub 2018 Oct 10.

University of Western Australia, Crawley, Washington, Australia.

Aim: To investigate and compare residual hearing preservation between patients based on the presence of intraoperative gusher.

Methodology: We retrospectively compared 2 cohorts of cochlear implant recipients significantly distinguished by whether or not they experienced gusher intraoperatively. Patients underwent cochlear implantation using 24-mm lateral wall electrode arrays as well pharmacologic steroid protection. Read More

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https://www.karger.com/Article/FullText/489599
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http://dx.doi.org/10.1159/000489599DOI Listing
October 2018
2 Reads

Id1/NR2B Receptor Pathway Regulates Rat Cochlear Sensory Epithelial Cell Survival after Radiation.

Audiol Neurootol 2018 9;23(3):173-180. Epub 2018 Oct 9.

Survival of cochlear sensory epithelial cells may be regulated by inhibitor of differentiation-1 (Id1) and the N-methyl-D-aspartic acid (NMDA) receptor. However, it is unclear whether Id1 and the NMDA receptor are involved in the radiation-mediated survival of rat cochlear sensory epithelial cells. Here, we show that the percentage of apoptotic cells increased, the percentage of cells in the S phase decreased, Id1 mRNA and protein expression decreased and the NMDA receptor subtype 2B (NR2B) mRNA and protein level increased in OC1 cells after radiation. Read More

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https://www.karger.com/Article/FullText/493084
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http://dx.doi.org/10.1159/000493084DOI Listing
October 2018
2 Reads

An Analysis of the Association between Epilepsy-Related Genes and Vertigo in the Polish Population.

Audiol Neurootol 2018 9;23(3):135-144. Epub 2018 Oct 9.

Division of Molecular and Forensic Genetics, Department of Forensic Medicine, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz,

Considering the possibility of a common genetic background of vertigo and epilepsy, we genotyped an affected group of individuals with vertigo and an unaffected group, by studying 26 single-nucleotide polymorphisms (SNPs) in 14 genes which were previously reported to be of particular importance for epilepsy. Significant differences were found between the patients and the control group (χ2 = 38.3, df = 3, p = 1. Read More

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http://dx.doi.org/10.1159/000491992DOI Listing
October 2018
1 Read

Hyperbaric Oxygen Therapy as Concurrent Treatment with Systemic Steroids for Idiopathic Sudden Sensorineural Hearing Loss: A Comparison of Three Different Steroid Treatments.

Audiol Neurootol 2018 9;23(3):145-151. Epub 2018 Oct 9.

Department of Otorhinolaryngology/Head and Neck Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.

We analyzed 356 patients with idiopathic sudden sensorineural hearing loss treated with hyperbaric oxygen therapy and systemic steroids (n = 161), systemic steroids alone (n = 160), or intratympanic and systemic steroids (n = 35). The main outcome measure was the hearing recovery rate. The effect of other variables, including the initial averaged 5-frequency hearing level, patient age, interval between the onset of symptoms and treatment, presence of vertigo as a complication, presence of diabetes mellitus, smoking history, and presence of hypertension, on the hearing recovery rate was also evaluated. Read More

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https://www.karger.com/Article/FullText/493083
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http://dx.doi.org/10.1159/000493083DOI Listing
October 2018
4 Reads

Cortical Processing of Frequency Changes Reflected by the Acoustic Change Complex in Adult Cochlear Implant Users.

Audiol Neurootol 2018 9;23(3):152-164. Epub 2018 Oct 9.

Department of Communication Sciences and Disorders, University of Cincinnati, Cincinnati, Ohio,

The purpose of this study was to examine neural substrates of frequency change detection in cochlear implant (CI) recipients using the acoustic change complex (ACC), a type of cortical auditory evoked potential elicited by acoustic changes in an ongoing stimulus. A psychoacoustic test and electroencephalographic recording were administered in 12 postlingually deafened adult CI users. The stimuli were pure tones containing different magnitudes of upward frequency changes. Read More

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https://www.karger.com/Article/FullText/492170
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http://dx.doi.org/10.1159/000492170DOI Listing
October 2018
3 Reads

Balance Control during Stance and Gait after Cochlear Implant Surgery.

Audiol Neurootol 2018 9;23(3):165-172. Epub 2018 Oct 9.

Department of ORL, University of Basel Hospital, Basel, Switzerland.

Background: After cochlear implant (CI) surgery, some patients experience vertigo, dizziness and/or deficits in vestibulo-ocular reflexes. However, little is known about the effect of CI surgery on balance control. Therefore, we examined differences in stance and gait balance control before versus after CI surgery. Read More

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http://dx.doi.org/10.1159/000492524DOI Listing
October 2018
2 Reads

Pediatric Auditory Brainstem Implantation: Impact on Audiological Rehabilitation and Tonal Language Development.

Audiol Neurootol 2018 18;23(2):126-134. Epub 2018 Sep 18.

Objective: This is a retrospective review of the impact of an Auditory Brainstem Implant (ABI) on the audiological rehabilitation and tonal language development of pediatric patients with prelingual profound deafness in Hong Kong.

Results: From January 2009 to February 2015, 11 pediatric patients with profound prelingual deafness received an ABI in Hong Kong (age range 1.67-3. Read More

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http://dx.doi.org/10.1159/000491991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214609PMC
September 2018

Evaluation of Hearing and Balance Functions of Patients with Sickle Cell Anemia.

Audiol Neurootol 2018 11;23(2):122-125. Epub 2018 Sep 11.

Hatay Mustafa Kemal University Medicine, Faculty Ear-Nose-Throat Department, Hatay, Turkey.

Introduction: Sickle cell anemia is a disease characterized by a wide vaso-occlusive incident from micro-vascular incident to muscularactivity. The cochlear function can also get affected by this vaso-occlusion.

Objective: It is aimed at determining what kind of effects sickle cell anemia has on hearing and balance system. Read More

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http://dx.doi.org/10.1159/000492171DOI Listing
September 2018
3 Reads

Inner Ear Damage by Firecracker Trauma.

Audiol Neurootol 2018 11;23(2):116-121. Epub 2018 Sep 11.

Firecrackers are still popular among the general public of various populations worldwide. This study investigated inner ear damage in patients with firecracker trauma and analyzed noise levels in 6 kinds of commercially available firecrackers. During the past 20 years, we have experienced 30 patients with firecracker trauma. Read More

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http://dx.doi.org/10.1159/000492611DOI Listing
September 2018

Minimal Reporting Standards for Active Middle Ear Hearing Implants.

Audiol Neurootol 2018 7;23(2):105-115. Epub 2018 Sep 7.

Department of Otolaryngology and Head and Neck Surgery, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.

There is currently no standardized method for reporting audiological, surgical and subjective outcome measures in clinical trials with active middle ear implants (AMEIs). It is often difficult to compare studies due to data incompatibility and to perform meta-analyses across different centres is almost impossible. A committee of ENT and audiological experts from Germany, Austria and Switzerland decided to address this issue by developing new minimal standards for reporting the outcomes of AMEI clinical trials. Read More

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http://dx.doi.org/10.1159/000490878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381865PMC
September 2018
18 Reads

Hearing Outcomes after Transmastoid Plugging of Superior Canal Dehiscence.

Audiol Neurootol 2018 31;23(2):98-104. Epub 2018 Aug 31.

Background: Patients with a superior canal dehiscence syndrome display symptoms of the vestibular disorder except that of hearing loss. Therefore, any type of surgery should treat those symptoms without affecting the hearing threshold. The aim of this study was to evaluate the extent to which the hearing threshold has been affected; the evaluation process was carried out by a transmastoid plugging of the superior canal. Read More

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https://www.karger.com/Article/FullText/492376
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http://dx.doi.org/10.1159/000492376DOI Listing
August 2018
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A Role for Acoustic Stimulation in Advanced Otosclerosis: Direct Acoustic Cochlear Implant versus Cochlear Implant.

Audiol Neurootol 2018 21;23(2):89-97. Epub 2018 Aug 21.

Department of Otolaryngology, Head and Neck Surgery, University Hospitals Leuven, Leuven, Belgium.

Recent findings support the efficacy of the direct acoustic cochlear implant (DACI) in patients with advanced otosclerosis whose rehabilitation is very challenging. Standard treatment consists of stapes surgery combined with hearing aids or a cochlear implant (CI). CI surgery, however, is often challenging depending on the grade of otosclerosis. Read More

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https://www.karger.com/Article/FullText/491990
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http://dx.doi.org/10.1159/000491990DOI Listing
August 2018
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Stapes Surgery for Otosclerosis in Patients Presenting with Mixed Hearing Loss.

Audiol Neurootol 2018 21;23(2):82-88. Epub 2018 Aug 21.

Objectives: To evaluate the efficacy of stapes surgery in patients presenting with a preoperative mixed hearing loss (bone conduction thresholds ≥40 dB; 40 < air conduction thresholds (AC) < 85 dB).

Patients And Methods: A total of 30 patients (32 ears) with mixed hearing loss who underwent primary stapedotomy were evaluated. Audiometric parameters were assessed before and after surgery. Read More

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http://dx.doi.org/10.1159/000489813DOI Listing

Evaluation of Sustained-Release Steroid Hydrogels in a Guinea Pig Model for Noise-Induced Hearing Loss.

Audiol Neurootol 2018 9;23(2):73-81. Epub 2018 Aug 9.

Department of Otorhinolaryngology, Medical University of Vienna, Vienna, Austria.

The otoprotective effects of thermoreversible poloxamer 407 hydrogels containing dexamethasone or triamcinolone acetonide were evaluated in an animal model of noise-induced hearing loss. Seven days after noise exposure, hearing threshold shifts at 16 kHz were significantly reduced in the 6% dexamethasone group (p < 0.05). Read More

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http://dx.doi.org/10.1159/000487662DOI Listing
August 2018
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Cochlear Function in Adults with Epilepsy and Treated with Carbamazepine.

Audiol Neurootol 2018 26;23(1):63-72. Epub 2018 Jul 26.

Audiology Unit, Department of ENT, Assiut University Hospital, Assiut, Egypt.

Background: Epilepsy is a chronic medical disease and is associated with comorbid adverse somatic conditions due to epilepsy itself or its long-term treatment.

Objectives: This study evaluated cochlear function in patients with idiopathic epilepsy and treated with carbamazepine (CBZ).

Patients And Methods: Included were 47 patients (mean age = 34. Read More

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http://dx.doi.org/10.1159/000490232DOI Listing

Trough-Shaped Audiograms Are Common in Patients with Acoustic Neuroma and Sudden Sensorineural Hearing Loss.

Audiol Neurootol 2018 18;23(1):58-62. Epub 2018 Jul 18.

Department of Otorhinolaryngology/Head and Neck Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.

Acoustic neuroma sometimes presents with sudden-onset sensorineural hearing loss as a primary symptom. We investigated 848 untreated cases that included 20 cases with acoustic neuroma with sudden-onset sensorineural hearing loss and 828 cases without acoustic neuroma. Fourteen of the 20 acoustic neuroma and 90 of the 828 cases of sudden-onset sensorineural hearing loss showed a trough-shaped audiogram with the greatest amount of hearing loss in the mid-frequency range. Read More

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http://dx.doi.org/10.1159/000490233DOI Listing
July 2018
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Late Cochlear Implantation in Early-Deafened Adults: A Detailed Analysis of Auditory and Self-Perceived Benefits.

Audiol Neurootol 2017 28;22(6):364-376. Epub 2018 Jun 28.

Department of Otorhinolaryngology, Head and Neck Surgery, Maastricht University Medical Center, Maastricht, the Netherlands.

Objectives: It is known that early-deafened cochlear implant (CI) users are a very heterogeneously performing group. To gain more insight into this population, this study investigated (1) postoperative changes in auditory performance over time based on various outcome measures, focusing on poor performers, (2) self-perceived outcomes, (3) relations between auditory and self-perceived outcomes, and (4) preimplantation factors predicting postoperative outcomes.

Methods: Outcomes were assessed prospectively in a group of 27 early-deafened, late-implanted CI users, up to 3 years after implantation. Read More

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http://dx.doi.org/10.1159/000488023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106129PMC
June 2018
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The Effect of Binaural Beamforming Technology on Speech Intelligibility in Bimodal Cochlear Implant Recipients.

Audiol Neurootol 2018 22;23(1):32-38. Epub 2018 Jun 22.

Although the benefit of bimodal listening in cochlear implant users has been agreed on, speech comprehension remains a challenge in acoustically complex real-life environments due to reverberation and disturbing background noises. One way to additionally improve bimodal auditory performance is the use of directional microphones. The objective of this study was to investigate the effect of a binaural beamformer for bimodal cochlear implant (CI) users. Read More

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http://dx.doi.org/10.1159/000487749DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172793PMC

Abnormal Cochleovestibular Anatomy and Hearing Outcomes: Pediatric Patients with a Questionable Cochleovestibular Nerve Status May Benefit from Cochlear Implantation and/or Hearing Aids.

Audiol Neurootol 2018 22;23(1):48-57. Epub 2018 Jun 22.

Tina and Rick Caruso Department of Otolaryngology-Head and Neck Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.

Objective: Imaging characteristics and hearing outcomes in children with cochleovestibular or cochleovestibular nerve (CVN) abnormalities.

Study Design: Retrospective, critical review.

Setting: Tertiary referral academic center. Read More

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http://dx.doi.org/10.1159/000488793DOI Listing
June 2018
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Cochlear Nerve Aplasia with Detectable Olivocochlear Efferent Function: A Distinct Presentation of Auditory Neuropathy Spectrum Disorder.

Audiol Neurootol 2018 22;23(1):39-47. Epub 2018 Jun 22.

Department of Otolaryngology-HNS, University of Toronto and The Hospital for Sick Children, Toronto, Ontario, Canada.

Background: Cochlear nerve aplasia (CNA) may present with features of auditory neuropathy spectrum disorder (ANSD), having detectable otoacoustic emissions (OAE) but profound hearing loss. We propose that some children with CNA have a distinct form of afferent ANSD in which efferent cochlear nerve function can be detected using contralateral suppression of OAE.

Methods: Children were prospectively enrolled with MRI and auditory brainstem response evidence of unilateral CNA, a normal contralateral ear, and detectable OAE bilaterally. Read More

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https://www.karger.com/Article/FullText/487584
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http://dx.doi.org/10.1159/000487584DOI Listing
June 2018
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Methionine Sulfoxide Reductase A Knockout Mice Show Progressive Hearing Loss and Sensitivity to Acoustic Trauma.

Audiol Neurootol 2018 21;23(1):20-31. Epub 2018 Jun 21.

Department of Hearing and Speech, School of Health Professions, University of Kansas Medical Center, Kansas City, Kansas, USA.

Methionine sulfoxide reductases (MsrA and MsrB) protect the biological activity of proteins from oxidative modifications to methionine residues and are important for protecting against the pathological effects of neurodegenerative diseases. In the current study, we characterized the auditory phenotype of the MsrA knockout mouse. Young MsrA knockout mice showed small high-frequency threshold elevations for auditory brainstem response and distortion product otoacoustic emission compared to those of wild-type mice, which progressively worsened in older MsrA knockout mice. Read More

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http://dx.doi.org/10.1159/000488276DOI Listing
June 2018
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Effect of Antioxidant Vitamins as Adjuvant Therapy for Sudden Sensorineural Hearing Loss: Systematic Review Study.

Audiol Neurootol 2018 22;23(1):1-7. Epub 2018 Jun 22.

Importance: Sudden sensorineural hearing loss (SSNHL) is an otological emergency of unknown etiology. Recent reports showed that antioxidant drugs can benefit patients with SSNHL. This study attempted to evaluate the effect of adding antioxidant vitamins as an adjuvant therapy alongside with corticosteroids. Read More

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http://dx.doi.org/10.1159/000486274DOI Listing
June 2018
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One-Year Results for Patients with Unilateral Hearing Loss and Accompanying Severe Tinnitus and Hyperacusis Treated with a Cochlear Implant.

Audiol Neurootol 2018 21;23(1):8-19. Epub 2018 Jun 21.

Cochlear EMEA, Basel, Switzerland.

Objective: To show that patients with unilateral hearing loss (UHL), with one ear fulfilling cochlear implant (CI) indication criteria, and an additional severe tinnitus handicap can be treated effectively with a CI.

Method: A prospective multi-centre study was conducted in five Spanish centres. Sixteen adult patients with UHL and a mean Tinnitus Handicap Inventory (THI) score of at least 58 were implanted. Read More

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http://dx.doi.org/10.1159/000488755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170998PMC
June 2018
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Predicting Sequential Cochlear Implantation Performance: A Systematic Review.

Audiol Neurootol 2017 2;22(6):356-363. Epub 2018 May 2.

Ear Science Institute Australia, Subiaco, Western Australia, Australia.

This systematic review of the literature reveals which pre-operative factors affect sequential cochlear implantation outcomes in adults. The findings can help health care prof-essionals provide evidence-based advice on the expected benefits from a second cochlear implant (CI). We searched PubMed, EMBASE, and the Cochrane database from November 1977 to August 26, 2017, using the terms "sequential cochlear implantation"; the most frequently cited predictors for unilateral cochlear implantation performance and other potential predictors for sequential implantation outcome; and "speech perception," "localization" as well as synonyms of all of the above. Read More

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http://dx.doi.org/10.1159/000488386DOI Listing
May 2018
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