3,504 results match your criteria Atypical Mycobacterial Diseases


Atypical bronchial carcinoid with postobstructive mycobacterial infection: case report and review of literature.

BMC Pulm Med 2019 Feb 15;19(1):41. Epub 2019 Feb 15.

Department of Pulmonary Medicine, Amsterdam University Medical Center, Amsterdam, The Netherlands.

Background: Pulmonary carcinoids are included in the group of neuroendocrine tumors (NET) and derive from pulmonary neuroendocrine cells. The incidence of these tumors is increasing, but disease awareness remains low among clinicians. The synchronous presentation of lung cancer and mycobacterial infection is well known but the combination of pulmonary carcinoid and mycobacterial infection is rare. Read More

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http://dx.doi.org/10.1186/s12890-019-0806-xDOI Listing
February 2019

[Mycobacterium marinum as a cause of human and animal infections].

Klin Mikrobiol Infekc Lek 2018 Dec;24(4):112-117

Veterinary Research Institute, Brno, Czech Republic, e-mail:

Mycobacterium marinum is a slowly growing non-tuberculous (environmental, atypical) mycobacterium with zoonotic potential. It occurs in the aquatic environment and causes diseases in fish and other aquatic animals known as mycobacterioses. In humans, it primarily causes skin infections, which are most commonly located in the upper limbs. Read More

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December 2018

Clinical features of Mycobacterium canettii infection: a retrospective study of 20 cases among French soldiers and relatives.

Clin Infect Dis 2019 Feb 7. Epub 2019 Feb 7.

Department of Biology, Percy Military Teaching Hospital, Clamart, France.

Background: Mycobacterium canettii forms part of the Mycobacterium tuberculosis complex. M. canettii infections are mainly described in the Horn of Africa. Read More

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http://dx.doi.org/10.1093/cid/ciz107DOI Listing
February 2019
1 Read

Mycobacterium fortuitum infection of a hemodialysis catheter in a pediatric patient.

Hemodial Int 2019 Feb 12. Epub 2019 Feb 12.

Pediatric Nephrology division, Children's Mercy Hospital, Kansas City, Missouri, USA.

This case report discusses a pediatric patient who developed a hemodialysis catheter line infection from an uncommon etiology, Mycobacterium fortuitum. The initial presentation revealed a well appearing patient with a slow growing skin lesion near the site of the hemodialysis catheter. The treatment course was complicated by resistance to initial antibiotics leading to continued spread of the lesion. Read More

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http://dx.doi.org/10.1111/hdi.12731DOI Listing
February 2019

Tuberculosis and atypical mycobacterial infections in ruxolitinib-treated patients with primary or secondary myelofibrosis or polycythemia vera.

Int J Infect Dis 2019 Jan 11;80:134-136. Epub 2019 Jan 11.

Department of Oncology and Haematology, Hôpitaux Universitaires de Strasbourg, Strasbourg, France; Université de Strasbourg, Inserm UMR-S1113/IRFAC, Strasbourg, France.

Ruxolitinib is a JAK-1/JAK-2 inhibitor indicated for the treatment of polycythemia vera and primary or secondary myelofibrosis. Only one patient (0.2%) was diagnosed with tuberculosis among the 485 patients receiving ruxolitinib in the four pivotal trials. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S12019712193001
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http://dx.doi.org/10.1016/j.ijid.2019.01.002DOI Listing
January 2019
8 Reads

Atypical rash.

Eur J Intern Med 2018 Dec 26. Epub 2018 Dec 26.

Infectious Diseases Section, Clinica Las Vegas, Medellín, Colombia.

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http://dx.doi.org/10.1016/j.ejim.2018.12.006DOI Listing
December 2018
1 Read

Curious case of fever of unknown origin.

BMJ Case Rep 2018 Dec 3;11(1). Epub 2018 Dec 3.

Professor, Department of Medicine, All India Institute of Medical Sciences, New Delhi.

A 58-year-old immunocompetent woman presented with fever and significant weight loss of 4-month duration. She had mild pallor; rest of the examination was unremarkable. Investigations revealed anaemia with raised inflammatory markers. Read More

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http://dx.doi.org/10.1136/bcr-2018-227258DOI Listing
December 2018
2 Reads

Drug Susceptibility of Non-tuberculous Strains of Isolated from Birds from Poland.

Pol J Microbiol 2018 ;67(4):487-492

Department of Pathology and Veterinary Diagnostics, Warsaw University of Life Sciences , Warsaw , Poland.

Mycobacterioses are a constant problem in backyard poultry, as well as pet birds. To date, no evidence of direct transmission of atypical bacilli between humans has been demonstrated, but it cannot be ruled out that sick animals can be a source of infection for people in their environment. The aim of the study was to identify mycobacteria isolated from birds with diagnosed mycobacteriosis and to determine the susceptibility of mycobacterial isolates from these animals to antituberculous drugs most commonly used in the treatment of mycobacterial infections in humans. Read More

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https://www.exeley.com/polish_journal_of_microbiology/doi/10
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http://dx.doi.org/10.21307/pjm-2018-057DOI Listing
January 2018
8 Reads

The association between computed tomography scan findings of pulmonary infection caused by atypical mycobacteria and bacillus count in sputum samples.

Int J Mycobacteriol 2018 Oct-Dec;7(4):355-357

Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Disease, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: The use of imaging techniques is important for prompt diagnosis and treatment of atypical mycobacterial infections; it also reduces the burden of these infections. The purpose of the present study was to determine the association between computed tomography (CT) scan findings of pulmonary infection caused by atypical mycobacteria and bacillus count in sputum samples.

Methods: This cross-sectional, observational, comparative study included 50 consecutive patients with pulmonary infection caused by atypical mycobacteria, who were hospitalized in Masih-Daneshvari Hospital of Tehran, Iran during 2012-2017. Read More

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http://dx.doi.org/10.4103/ijmy.ijmy_139_18DOI Listing
December 2018
2 Reads

Mycobacterial Tenosynovitis After Sea Urchin Spine Injury in an Immunocompromised Patient.

Open Forum Infect Dis 2018 Nov 2;5(11):ofy285. Epub 2018 Nov 2.

Department of Surgery, Plastic Surgery Section, Louis Stokes Cleveland Veterans Affairs Medical Center, Ohio.

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https://academic.oup.com/ofid/advance-article/doi/10.1093/of
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http://dx.doi.org/10.1093/ofid/ofy285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262115PMC
November 2018
12 Reads

A Case of Generalized, Superinfected Dermatitis and Inguinal Mycobacterium Lymphadenitis - TB or not TB?

Acta Dermatovenerol Croat 2018 Oct;26(3):270-272

Gyula Laszlo Fekete, MD, Bdul. 1 Decembrie 1918, no. 211/27, Tg. Mures, Romania:

Dear Editor, Eczema is an inflammatory dermatitis mediated by cellular immunity, with an etiology in which environmental, immunological, and genetic factors are involved. Skin inflammation through proinflammatory cytokines creates a favorable environment for microbial antigens and optimal conditions for infection (1). In case of underlying immunosuppression, inflammatory features of dermatitis and superimposed infections are more severe. Read More

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October 2018
13 Reads

Surgical Site Infections due to Non-Tuberculous Mycobacteria.

JNMA J Nepal Med Assoc 2018 Mar-Apr;56(211):696-700

Department of General Surgery, Nobel Medical College, Biratnagar, Morang, Nepal.

Introduction: Non-tuberculous Mycobacteria are increasingly recognized, nowadays as an important pathogen in delayed surgical site infection in post operative cases. We here in describe cases of surgical site infection caused by Non-tuberculous Mycobacteria, seen in two centers in Jhapa. The aim of the study was to increase awareness of this atypical mycobacterial infection, prompt diagnosis, and treatment that may ultimately provide better care to patients. Read More

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November 2018

The Mycobacterial Cell Envelope: A Relict From the Past or the Result of Recent Evolution?

Front Microbiol 2018 9;9:2341. Epub 2018 Oct 9.

INRS-Institut Armand-Frappier, Bacterial Symbionts Evolution, Laval, QC, Canada.

Mycobacteria are well known for their taxonomic diversity, their impact on global health, and for their atypical cell wall and envelope. In addition to a cytoplasmic membrane and a peptidoglycan layer, the cell envelope of members of the order , which include , also have an arabinogalactan layer connecting the peptidoglycan to an outer membrane, the so-called "mycomembrane." This unusual cell envelope composition of mycobacteria is of prime importance for several physiological processes such as protection from external stresses and for virulence. Read More

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http://dx.doi.org/10.3389/fmicb.2018.02341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194230PMC
October 2018
2 Reads

Cutaneous Infection With Mycobacterium haemophilum in an Immunocompromised Patient.

Iran J Kidney Dis 2018 Oct;12(5):312-314

Infectious Diseases and Tropical Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Mycobacterium haemophilum is a fastidious nontuberculosis Mycobacterium that must be considered in the differential diagnosis of infections in immunocompromised patients. Mycobacterium haemophilum typically is a pathogen of the cutaneous or subcutaneous tissue and also presents as septic arthritis, osteomyelitis, pulmonary disease, and lymphadenitis. We report a 32-year-old man with past medical history of kidney transplantation, endocarditis, gastrointestinal bleeding, and hypertension, complaining of multiple painful nodular lesions since 3 months earlier. Read More

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October 2018
15 Reads

Lymphadenitis by non-tuberculous mycobacteria in children.

Pediatr Int 2018 Dec 10;60(12):1062-1067. Epub 2018 Dec 10.

Department of Paediatrics, Archbishop Makarios III Hospital, Nicosia, Cyprus.

Background: Non-tuberculous mycobacteria (NTM) constitute an important cause of cervical lymphadenitis in immunocompetent children. The aims of this study were to estimate the incidence of lymphadenitis due to NTM in children in Cyprus and to describe the characteristics, diagnostic approach, management and outcome of such infections.

Methods: Children aged 1-5 years old, evaluated at Archbishop Makarios III Hospital, Nicosia, Cyprus, from 1 January 2007 to 31 December 2016 for lymphadenopathy, were included in the study. Read More

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http://dx.doi.org/10.1111/ped.13708DOI Listing
December 2018
6 Reads

Immunological correlates of mycobacterial growth inhibition describe a spectrum of tuberculosis infection.

Sci Rep 2018 Sep 27;8(1):14480. Epub 2018 Sep 27.

The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

A major contribution to the burden of Tuberculosis (TB) comes from latent Mycobacterium tuberculosis infections (LTBI) becoming clinically active. TB and LTBI probably exist as a spectrum and currently there are no correlates available to identify individuals with LTBI most at risk of developing active disease. We set out to identify immune parameters associated with ex vivo mycobacterial growth control among individuals with active TB disease or LTBI to define the spectrum of TB infection. Read More

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http://dx.doi.org/10.1038/s41598-018-32755-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160428PMC
September 2018
12 Reads

A Rare Catch in a Nonhealing Wound.

Wounds 2018 Sep;30(9):E87-E88

Houston Methodist Hospital, Houston, TX.

Introduction: Mycobacterium smegmatis is a common microbe found in soil, dust, and water that rarely causes infections in humans.

Case Report: A 45-year-old man with a past medical history of hypertension presented with a nonhealing surgical wound in his anterior chest wall, measuring 0.5 cm x 0. Read More

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September 2018
15 Reads

Mycobacterium abscessus infection in a spa worker.

Acta Dermatovenerol Alp Pannonica Adriat 2018 Sep;27(3):159-160

Department of Dermatology and Venereology, Centro Hospitalar São João, EPE, Porto, Portugal.

Mycobacterium abscessus (M. abscessus) is a non-tuberculous mycobacterium widely present in the natural environment and is now being increasingly identified as a cause of human disease. However, it can cause skin and soft tissue infection following trauma or surgery. Read More

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September 2018
2 Reads

Inflammatory Reactions to Red Tattoo Inks: Three cases highlighting an emerging problem.

Sultan Qaboos Univ Med J 2018 May 9;18(2):e215-e218. Epub 2018 Sep 9.

Department of Dermatology, Hospital Universitario Campus de la Salud, Granada, Spain.

In recent years, tattoos have become more commonplace. However, this can result in various inflammatory processes, the management of which can be challenging in daily clinical practice. Tattoo-related inflammatory reactions can comprise different patterns, including acute and immediate reactions, foreign body granulomas, sarcoid granulomas, isomorphic lesions, allergic contact dermatitis and photosensitivity. Read More

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https://journals.squ.edu.om/index.php/squmj/article/view/272
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http://dx.doi.org/10.18295/squmj.2018.18.02.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132509PMC
May 2018
4 Reads

Hypercalcemia-induced acute kidney injury in a Caucasian female due to radiographically silent systemic sarcoidosis.

Clin Nephrol Case Stud 2018 4;6:21-26. Epub 2018 Sep 4.

Division of Nephrology.

. Sarcoidosis is a rare autoimmune disease resulting in formation of non-necrotizing "non-caseating" granulomas generally in the lung. The disease classically strikes African American females in their fourth and fifth decades. Read More

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http://dx.doi.org/10.5414/CNCS109513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125993PMC
September 2018
4 Reads

Therapeutic implications of nano-encapsulated rifabutin, azithromycin & ethambutol against experimental infection in mice.

Indian J Med Res 2018 06;147(6):594-602

Department of Biochemistry, Postgraduate Institute of Medical Education & Research, Chandigarh, India.

Background & Objectives: Mycobacterium avium causes atypical infection in both immunocompetent and immunocompromised individuals. Conventional chemotherapy for M. avium infection is not efficient due to lengthy course of treatment and drug-associated toxic side effects. Read More

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http://www.ijmr.org.in/text.asp?2018/147/6/594/239930
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http://dx.doi.org/10.4103/ijmr.IJMR_2004_15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118139PMC
June 2018
15 Reads
1.660 Impact Factor

Extrapulmonary tuberculosis: atypical presentation in otorhinolaryngology.

BMJ Case Rep 2018 Aug 29;2018. Epub 2018 Aug 29.

ENT, Head and Neck Surgery, Sri Ramachandra University Medical College, Chennai, Tamil Nadu, India.

Tuberculosis (TB) continues to be a major health burden globally more so in low/middle-income countries like India. There is an increase in the prevalence of extrapulmonary TB (EPTB) because of HIV epidemics and increased usage of immunomodulating drugs. EPTB constitutes 15%-20% of all patients with TB and >50% of HIV-TB coinfected patients. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22480
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http://dx.doi.org/10.1136/bcr-2018-224802DOI Listing
August 2018
16 Reads

Cutaneous atypical mycobacteriosis with sporotrichoid clinical presentation caused by automotive accident.

An Bras Dermatol 2018 Sep-Oct;93(5):743-745

Infectious Diseases Clinic, Hospital da Santa Casa de São Paulo, São Paulo (SP), Brazil.

Atypical mycobacterial infections are caused by mycobacteria other than those from the M. tuberculosis complex and M. leprae. Read More

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S
Publisher Site
http://dx.doi.org/10.1590/abd1806-4841.20187586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106664PMC
October 2018
16 Reads

Delayed diagnosis of extrapulmonary tuberculosis presenting as fever of unknown origin in an intermediate-burden country.

BMC Infect Dis 2018 Aug 28;18(1):426. Epub 2018 Aug 28.

Department of Internal Medicine, Boramae Medical Center, 20, Boramae-ro 5-gil, Dongjak-gu, Seoul, 07061, South Korea.

Background: Tuberculosis (TB), especially extrapulmonary tuberculosis (EPTB), is an important cause of fever of unknown origin (FUO) in TB-burdened areas. Little information is known about patients with EPTB with clinical features presenting as FUO and about the factor of delaying the diagnosis.

Methods: We retrospectively analyzed EPTB patients who were referred with FUO at 3 university-affiliated hospitals over 8 years (2010-2017). Read More

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http://dx.doi.org/10.1186/s12879-018-3349-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114835PMC
August 2018
5 Reads

Emerging and re-emerging infectious disease in otorhinolaryngology.

Acta Otorhinolaryngol Ital 2018 Apr;38(SUPPL. 1):S1-S106

SOC Neuroanestesia e Rianimazione, A.O.U. Careggi, Firenze, Italy.

Summary: Emerging and re-emerging infectious disease in otorhinolaryngology (ENT) are an area of growing epidemiological and clinical interest. The aim of this section is to comprehensively report on the epidemiology of key infectious disease in otorhinolaryngology, reporting on their burden at the national and international level, expanding of the need of promoting and implementing preventive interventions, and the rationale of applying evidence-based, effective and cost- effective diagnostic, curative and preventive approaches. In particular, we focus on i) ENT viral infections (HIV, Epstein-Barr virus, Human Papilloma virus), retrieving the available evidence on their oncogenic potential; ii) typical and atypical mycobacteria infections; iii) non-specific granulomatous lymphadenopathy; iv) emerging paediatric ENT infectious diseases and the prevention of their complications; v) the growing burden of antimicrobial resistance in ENT and the strategies for its control in different clinical settings. Read More

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http://www.actaitalica.it/issues/2018/2-2018S1/Suppl._Relazi
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056203PMC
http://dx.doi.org/10.14639/0392-100X-suppl.1-38-2018DOI Listing
April 2018
3 Reads

Endobronchial Non-Tuberculosis Mycobacterium Infection Presenting in a Healthy Child.

Ann Otol Rhinol Laryngol 2018 Oct 2;127(10):726-730. Epub 2018 Jul 2.

2 Department of Otolaryngology, Children's Mercy Hospital, Kansas City, Missouri, USA.

Objectives: To describe a safe and effective treatment for endobronchial Mycobacterium avium complex.

Methods: Case report and literature review.

Results: We present a case of endobronchial M. Read More

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http://dx.doi.org/10.1177/0003489418784970DOI Listing
October 2018
3 Reads

The Child with Recurrent Mycobacterial Disease.

Curr Allergy Asthma Rep 2018 Jun 23;18(8):44. Epub 2018 Jun 23.

Department of Pediatrics, Allergy-Immunology and Pediatric Rheumatology Division, Medical College of Georgia at Augusta University, 1120 15th Street, Augusta, GA, 30912, USA.

Purpose Of Review: Many genetic conditions predispose affected individuals to opportunistic infections. A number of immunodeficiency diseases, including genetic defects termed Mendelian susceptibility to mycobacterial disease (MSMD), permit infection from many different strains of mycobacteria that would otherwise not cause disease. These include tuberculous and nontuberculous mycobacteria, and bacille Calmette-Guérin vaccine (BCG). Read More

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http://dx.doi.org/10.1007/s11882-018-0797-3DOI Listing
June 2018
8 Reads

A study of a pancreatic mass: not all is what it seems.

Rev Esp Enferm Dig 2018 07;110(7):470-471

Gastroenterología y Hepatología, Hospital Universitario la Paz.

We report the case of a male with no medical history with acute cholangitis secondary to a pancreatic head´s mass suggestive of neoplasm. An EUS-FNA was performed where no atypical cells were identified but a granulomatous component did. The patient was finally diagnosed of disseminated tuberculosis with pancreatic involvement. Read More

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http://dx.doi.org/10.17235/reed.2018.5527/2018DOI Listing
July 2018
1 Read

The domain architecture of PtkA, the first tyrosine kinase from , differs from the conventional kinase architecture.

J Biol Chem 2018 07 8;293(30):11823-11836. Epub 2018 Jun 8.

From the Institute for Organic Chemistry and Chemical Biology, Centre for Biomolecular Magnetic Resonance (BMRZ), Goethe-University Frankfurt am Main, Max-von-Laue-Strasse 7, D-60438 Frankfurt am Main, Germany

The discovery that MptpA (low-molecular-weight protein tyrosine phosphatase A) from () has an essential role for virulence has motivated research of tyrosine-specific phosphorylation in and other pathogenic bacteria. The phosphatase activity of MptpA is regulated via phosphorylation on Tyr and Tyr Thus far, only a single tyrosine-specific kinase, protein-tyrosine kinase A (PtkA), encoded by the gene has been identified within the genome. MptpA undergoes phosphorylation by PtkA. Read More

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http://dx.doi.org/10.1074/jbc.RA117.000120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066317PMC
July 2018
15 Reads
4.573 Impact Factor

Risk factors and variations in detection of new bovine tuberculosis breakdowns via slaughterhouse surveillance in Great Britain.

PLoS One 2018 8;13(6):e0198760. Epub 2018 Jun 8.

Disease Dynamics Unit, Department of Veterinary Medicine, University of Cambridge, Cambridge, Cambridgeshire, United Kingdom.

Slaughterhouse surveillance through post-mortem meat inspection provides an important mechanism for detecting bovine tuberculosis (bTB) infections in cattle herds in Great Britain (GB), complementary to the live animal skin test based programme. We explore patterns in the numbers of herd breakdowns detected through slaughterhouse surveillance and develop a Bayesian hierarchical regression model to assess the associations of animal-level factors with the odds of an infected animal being detected in the slaughterhouse, allowing us to highlight slaughterhouses that show atypical patterns of detection. The analyses demonstrate that the numbers and proportions of breakdowns detected in slaughterhouses increased in GB over the period of study (1998-2013). Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0198760PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993271PMC
January 2019
17 Reads

Tenosynovitis with Rice Body Formation Due to Mycobacterium Intracellulare Infection After Initiation of Infliximab Therapy.

Am J Case Rep 2018 Jun 7;19:656-662. Epub 2018 Jun 7.

Department of Respiratory Medicine, Kyorin University School of Medicine, Mitaka, Tokyo, Japan.

BACKGROUND Rheumatoid arthritis tenosynovitis is difficult to discriminate from non-tuberculous tenosynovitis on the basis of radiological and pathological findings. CASE REPORT A 74-year-old woman with a 4-year history of rheumatoid arthritis was referred to our hospital to undergo treatment for uncontrollable tenderness and swelling in her right third metacarpophalangeal joint, right wrist, and left knee joint. In the previous year, she underwent surgery at a local hospital for the swelling in her right metacarpophalangeal joint, the information of which was not known precisely, but the swelling subsided in due course after an operation. Read More

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http://dx.doi.org/10.12659/AJCR.908785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020799PMC
June 2018
4 Reads

Disseminated mycobacteriosis caused by Mycobacterium kansasii in a pot-bellied pig.

J Vet Diagn Invest 2018 Jul 1;30(4):646-650. Epub 2018 Jun 1.

Indiana Animal Disease Diagnostic Laboratory and the Departments of Comparative Pathobiology (Schafbuch, Ramos-Vara), College of Veterinary Medicine, Purdue University, West Lafayette, IN.

A 1.5-y-old spayed female Juliana pot-bellied pig was presented to the Purdue University Veterinary Teaching Hospital with a history of wasting and anorexia. Enlarged and partially mineralized lymph nodes were identified on radiographs and computed tomography scan. Read More

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http://dx.doi.org/10.1177/1040638718780189DOI Listing

Cutaneous squamous cell carcinoma, thyroid cancer and Langerhans cell histiocytosis in a patient with X-linked recessive Mendelian susceptibility to mycobacterial diseases with a nuclear factor-κB essential modifier mutation.

J Dermatol 2018 Aug 24;45(8):1017-1019. Epub 2018 May 24.

Department of Dermatology, Gunma University Graduate School of Medicine, Maebashi, Japan.

Nuclear factor (NF)-κB essential modifier (NEMO), also known as IκB kinase subunit-γ (IKKγ), is a pivotal molecule in the NF-κB signaling pathway. Mutations of NEMO cause incontinentia pigmenti and X-linked ectodermal dysplasia with immunodeficiency. Mendelian susceptibility to mycobacterial diseases (MSMD), which confers an almost selective predisposition to mycobacterial infection, is also caused by NEMO mutations. Read More

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http://doi.wiley.com/10.1111/1346-8138.14482
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http://dx.doi.org/10.1111/1346-8138.14482DOI Listing
August 2018
7 Reads

Autosomal Dominant IFN-γR1 Deficiency Presenting with both Atypical Mycobacteriosis and Tuberculosis in a BCG-Vaccinated South African Patient.

J Clin Immunol 2018 May 18;38(4):460-463. Epub 2018 May 18.

DST/NRF Centre of Excellence for Biomedical Tuberculosis Research; South African Medical Research Council Centre for Tuberculosis Research; Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 241, 8000, Francie van Zijl Drive, Tygerberg, Cape Town, 7505, South Africa.

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http://link.springer.com/10.1007/s10875-018-0509-8
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http://dx.doi.org/10.1007/s10875-018-0509-8DOI Listing
May 2018
16 Reads

[Non-tuberculous mycobacterial cervical adenitis in children: 2 cases].

Ann Dermatol Venereol 2018 Aug - Sep;145(8-9):505-511

Service de dermatologie, CHU d'Angers, 4, rue Larrey, 49100 Angers, France.

Background: Cervical lymphadenitis is the most common manifestation of infection with nontuberculous mycobacteria (NTM) in immunocompetent children. Nevertheless, it is poorly known by dermatologists. Its incidence, which is currently increasing since the cessation of BCG vaccination in 2007, raises several issues regarding its pathophysiology, diagnosis and management. Read More

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http://dx.doi.org/10.1016/j.annder.2018.02.018DOI Listing
March 2017
4 Reads

An atypical infection of the esophagus mimicking malignancy.

Gastrointest Endosc 2018 10 21;88(4):765-766. Epub 2018 Jun 21.

Department of Internal Medicine, Far Eastern Memorial Hospital, Ban-Ciao, New Taipei City, Taiwan, Republic of China; College of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan, Republic of China.

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http://dx.doi.org/10.1016/j.gie.2018.05.007DOI Listing
October 2018

Tuberculous peritonitis and pleurisy accompanied by pulmonary cryptococcosis: A case report.

J Int Med Res 2018 Jul 13;46(7):2976-2982. Epub 2018 May 13.

The Third Comprehensive Department, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou, Guangdong 510006, China.

Although the infectious diseases tuberculosis (TB) and cryptococcosis both cause formation of single or multiple nodules in immunodeficient hosts, cases of co-infection of these diseases are rarely seen. We report a patient who was co-infected with TB and cryptococcosis. A male patient with no clinical evidence of immunodeficiency presented with a 3-week history of abdominal distension accompanied by oedema of recurring lower extremities. Read More

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http://dx.doi.org/10.1177/0300060518773239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124282PMC

Pulmonary Mycobacterial Spindle Cell Pseudotumor: A Report of 3 Cases Including a Practical Approach to Histopathologic Recognition of This Unusual Entity.

Int J Surg Pathol 2018 Oct 2;26(7):629-634. Epub 2018 May 2.

1 Department of Pathology, University of Utah School of Medicine and Associated Regional and University Pathologists Laboratories, Salt Lake City, UT, USA.

Mycobacterial spindle cell pseudotumor (MSP) is a rare benign spindle cell lesion containing acid-fact mycobacteria. These lesions are most commonly identified in the lymph nodes, skin, spleen, or bone marrow of immunocompromised patients and only rarely involve the lungs. We report 3 cases of pulmonary MSP, which include 2 patients who are known to be HIV-positive. Read More

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http://dx.doi.org/10.1177/1066896918770010DOI Listing
October 2018
5 Reads

Incidental intraoperative diagnosis of Mycobacterium abscessus meningeal infection: a case report and review of the literature.

Infection 2018 Oct 23;46(5):591-597. Epub 2018 Apr 23.

Department of Neurosurgery, Catholic University of Rome, Largo A. Gemelli 8, 00168, Rome, Italy.

Purpose: Mycobacterium abscessus, and rapidly growing mycobacteria in general, are rare but increasing causes of central nervous system (CNS) infections. The aim of this study is to highlight the importance of considering these microorganism in the differential diagnosis of CNS infections, obtaining a prompt diagnosis, and improving clinical outcomes.

Methods: Case report and literature review. Read More

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http://dx.doi.org/10.1007/s15010-018-1141-5DOI Listing
October 2018
8 Reads

Atypical mycobacteriosis in a poorly compliant patient.

BMJ Case Rep 2018 Apr 7;2018. Epub 2018 Apr 7.

Department of Internal Medicine, Hospital de Cascais Dr. José de Almeida, Alcabideche, Cascais, Portugal.

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2017-22190
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http://dx.doi.org/10.1136/bcr-2017-221902DOI Listing
April 2018
3 Reads

Hot Tub Lung: An Intriguing Diffuse Parenchymal Lung Disease.

Ghana Med J 2017 Sep;51(3):143-147

Lousiana State University Health Science Center. Shreveport. LA, USA.

In pulmonary medicine, identical pathogenesis due to varied etiological agents can present with indistinguishable clinical presentation, and produce similar laboratory and radiological changes. The importance of eliciting detailed occupational and social history from patients cannot be stressed enough when dealing with patients suffering from diffuse parenchymal lung diseases. Hot Tub Lung(HTL) is a perplexing pulmonary disease attributed to the Mycobacterium Avium-intracellulare Complex (MAC). Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870233PMC
September 2017
7 Reads

Prevalence of bovine and avian tuberculosis in camel herds and associated public health risk factors in Isiolo County, Kenya.

Trop Anim Health Prod 2018 Jun 26;50(5):937-945. Epub 2018 Mar 26.

Kenya Camel Association, P.O. Box 6067, Nairobi, 00100, Kenya.

A cross-sectional study was conducted among 308 lactating camels selected from 15 herds from three different camel milk clusters in Isiolo County, Kenya, to determine prevalence of bovine and avian tuberculosis using Single Comparative Intradermal Tuberculin Skin test. Seventy-five (75) questionnaires were administered to pastoralists/herders, and focus group discussions were conducted among 3-5 pastoralists/herders selected from each camel herd to collect information on camel husbandry and health management practices and knowledge on tuberculosis in livestock and wildlife. An overall prevalence of bovine and avian reactors was 3. Read More

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http://dx.doi.org/10.1007/s11250-017-1486-2DOI Listing
June 2018
4 Reads

Atypical Mycobacterial Infections of the Upper Extremity.

Orthopedics 2018 May 26;41(3):e383-e388. Epub 2018 Mar 26.

Atypical mycobacterial infections of upper extremity synovial-lined structures are often misdiagnosed and unrecognized. Despite an increasing incidence, lack of physician awareness of these pathogens may result in considerable delay in diagnosis and management, potentially leading to permanent disability. The authors conducted a literature review and analyzed 31 cases of penetrating atypical mycobacterial infection to better understand the clinical characteristics and to evaluate their posttreatment complication rate compared with available literature. Read More

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http://dx.doi.org/10.3928/01477447-20180320-06DOI Listing
May 2018
5 Reads

Marine Develops Chronic Right Knee Granuloma After Initial Injury at The Basic School.

Mil Med 2018 Nov;183(11-12):e748-e750

Department of Dermatology, Naval Hospital Camp Pendleton, 200 Mercy Ct, Camp Pendleton, CA.

With skin lesions that have failed previous treatments, consideration for an atypical mycobacteria, specifically Mycobacterium marinum, infection should be suspected. Importance of the history cannot be stressed as this is a clue that the patient may have been inoculated and infected in the field environment. A marine with chronic right knee plaque for 3 yr that first appeared after a field exercise at The Basic School but worsened despite treatment with clindamycin, TMP-SMX, and incision and drainage in 2012. Read More

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http://dx.doi.org/10.1093/milmed/usx188DOI Listing
November 2018
1 Read

Prevalence of diabetes mellitus (DM) in tuberculosis (TB) patients: clinical and radiologic features in the TB-DM association based on a five-year hospital study.

Infez Med 2018 Mar;26(1):22-27

University of Belgrade, School of Medicine, Belgrade, Serbia; Students of Medicine Research Center, Belgrade, Serbia; Teaching Hospital of Pulmonology, Clinical Center of Serbia, Belgrade, Serbia.

A previously known association of tuberculosis (TB), now a global emergency, with diabetes mellitus (DM), a chronic disease of increasing prevalence worldwide, has resurfaced. DM is a recognised TB risk factor and M. tuberculosis infection usually disturbs glycoregulation. Read More

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March 2018
3 Reads

Atypical presentation of aural tuberculosis with complication.

BMJ Case Rep 2018 Mar 9;2018. Epub 2018 Mar 9.

Department of ENT and Head and Neck Surgery, All India Institute of Medical Sciences, New Delhi, India.

Tuberculosis involving mastoid and ear is an uncommon entity presenting with myriads of non-specific features and difficult to diagnose, being a paucibacillary condition. The involvement of otomastoid compartment is hypothesised to be of haematogenous origin. Rarely it can spread directly via tympanic membrane perforation or via reflux through eustachian tube. Read More

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http://dx.doi.org/10.1136/bcr-2017-222482DOI Listing
March 2018
10 Reads

Impact of introduction of Xpert MTB/RIF test on tuberculosis (TB) diagnosis in a city with high TB incidence in Brazil.

PLoS One 2018 8;13(3):e0193988. Epub 2018 Mar 8.

Programa de Pós-Graduação em Ciências Pneumológicas da Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.

Background: Xpert MTB/RIF is increasingly used in many countries as the initial diagnostic test for tuberculosis (TB). Few studies have evaluated the effect of Xpert on TB diagnosis under programmatic conditions in Brazil. The aim of the present study was to evaluate the impact of introduction of Xpert MTB/RIF on TB diagnosis in a city with high TB incidence in Brazil. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0193988PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843278PMC
July 2018
9 Reads

Skipped multifocal extensive spinal tuberculosis involving the whole spine: A case report and literature review.

Medicine (Baltimore) 2018 Jan;97(3):e9692

Department of Orthopedics, Zhongnan Hospital of Wuhan University.

Rationale: Skipped multifocal extensive spinal tuberculosis (TB) involving the whole spine is very rare. So far, only 3 cases have been reported.

Patient Concerns: We report a rare case of skipped multifocal extensive TB involving the whole spine of a 33-year-old Chinese male. Read More

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http://dx.doi.org/10.1097/MD.0000000000009692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779791PMC
January 2018
7 Reads

Non-responsive breast cellulitis after hyaluronic acid filler injection.

Int J Infect Dis 2018 05 2;70:57-58. Epub 2018 Mar 2.

Department of General Medicine, Division of Infectious Diseases, Changi General Hospital, 2 Simei Street 3, 529889, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.ijid.2018.02.018DOI Listing
May 2018
1 Read

Nontuberculous mycobacterial lung disease in a patient with COPD and bronchiectasis, with radiological signs of lung tumor.

Adv Respir Med 2018 ;86(1):17-22

Instytut Grużicy i Chorób Płuc, UL. Płocka 26, 01-138 Warszawa, Poland.

Mycobacterial lung disease is caused by nontuberculous mycobacteria (NTM), also known as atypical mycobacteria. NTM are widely distributed in the environment, particularly in soil and water; they may colonize the airways, gastrointestinal tract and genitourinary system, without the apparent signs of disease. Nevertheless, in some risk groups such as patients with chronic lung diseases or with immunodeficiency, mycobacterial lung disease is identified. Read More

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http://dx.doi.org/10.5603/ARM.2018.0005DOI Listing
September 2018
16 Reads