3,516 results match your criteria Atypical Mycobacterial Diseases


bacteremia in an immunocompetent host.

IDCases 2019 12;15:e00523. Epub 2019 Mar 12.

Infectious Diseases Consultant, Columbus Regional Hospital, Columbus, IN, United States.

Non-tuberculous mycobacteria can cause catheter associated blood stream infections. The causative agents are generally rapid growers that belong to the Mycobacterium fortuitum and Mycobacterium mucogenicum groups. A 65 year hospitalized patient with temporary central venous catheter who developed Mycobacterium smegmatis bacteremia. Read More

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https://data.crossref.org/10.1016%2Fj.idcr.2019.e00523
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http://dx.doi.org/10.1016/j.idcr.2019.e00523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430072PMC
March 2019
3 Reads

pneumonia: An unusual presentation of nontuberculous mycobacterial infection requiring a novel multidisciplinary approach to management.

Respir Med Case Rep 2019 28;26:307-309. Epub 2019 Feb 28.

Department of Respiratory Medicine, Galway University Hospital, Ireland.

Background: is a rapidly growing nontuberculous mycobacterium which has been associated with several infections including cellulitis, osteomyelitis, lymphadenitis, infected pacemakers and bursitis but it is a rare cause of respiratory infection.

Case Presentation: In this case report we describe a 51-year-old woman who presented with a 6-week history of non-productive cough, pleuritic chest pain and weight loss. She had a history of gastric adenocarcinoma managed with a distal oesophagectomy and total gastrectomy and consequentially suffered severe post-operative gastric reflux. Read More

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http://dx.doi.org/10.1016/j.rmcr.2019.02.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404650PMC
February 2019
3 Reads

An unusual case of unresolving tunnel infection in a patient on continuous ambulatory peritoneal dialysis.

Indian J Med Microbiol 2018 Oct-Dec;36(4):600-602

Department of Nephrology, Institue of Kidney Disease Urology and Organ Transplantation, Madras Medical Mission, Chennai, Tamil Nadu, India.

Atypical mycobacteria remain a rare cause of peritoneal dialysis catheter-related tunnel infection (TI) and poses serious risk because of the resistant nature to most antibiotic therapy. Non-tubercular mycobacterial infections lead to chronicity requiring peritoneal dialysis catheter removal. We report an 82-year-old male, with diabetic nephropathy who had a coinfection with Staphylococcus hominis and Mycobacterium abscessus who presented with pus discharge at exit site and TI. Read More

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http://dx.doi.org/10.4103/ijmm.IJMM_18_425DOI Listing
March 2019
1 Read

Mycobacterial Infections in Patients With Chronic Kidney Disease and Kidney Transplantation.

Adv Chronic Kidney Dis 2019 Jan;26(1):35-40

Scott & White Medical Center-Temple, Division of Infectious Diseases, Department of Medicine, Texas A&M Health Science Center College of Medicine, TX.

Patients with chronic kidney disease have impaired immunity that increases their risk of infection. Increased incidence of mycobacterial infections, in particular Mycobacterium tuberculosis, is described in patients undergoing hemodialysis and peritoneal dialysis as well as after kidney transplantation in low-prevalence and high-prevalence settings. Diagnosis of this infection can be challenging because of atypical presentations that may lead to treatment delay and, consequently, increased mortality; however, recent advances in molecular testing have improved diagnostic accuracy. Read More

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http://dx.doi.org/10.1053/j.ackd.2018.09.004DOI Listing
January 2019
1 Read

Atypical testicular pain.

BMJ Case Rep 2019 Feb 19;12(2). Epub 2019 Feb 19.

Urological Surgery, Wexham Park Hospital, Frimley Health NHS Foundation Trust, Frimley, UK.

Testicular tuberculosis (TB) is rare, and, because of this, the lack of pathognomonic clinical features and its tendency to mimic other commoner conditions, the diagnosis is frequently delayed or may be missed. In this case, the initial clinical presentation was typical for bacterial epididymo-orchitis in a 38-year-old man. When the patient failed to improve with standard treatment including broadening of antibiotics, the diagnosis was re-considered because some unusual signs suggested testicular malignancy or lymphoma. Read More

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http://dx.doi.org/10.1136/bcr-2018-226697DOI Listing
February 2019
1 Read

Atypical bronchial carcinoid with postobstructive mycobacterial infection: case report and review of literature.

BMC Pulm Med 2019 Feb 15;19(1):41. Epub 2019 Feb 15.

Department of Pulmonary Medicine, Amsterdam University Medical Center, Amsterdam, The Netherlands.

Background: Pulmonary carcinoids are included in the group of neuroendocrine tumors (NET) and derive from pulmonary neuroendocrine cells. The incidence of these tumors is increasing, but disease awareness remains low among clinicians. The synchronous presentation of lung cancer and mycobacterial infection is well known but the combination of pulmonary carcinoid and mycobacterial infection is rare. Read More

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http://dx.doi.org/10.1186/s12890-019-0806-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376781PMC
February 2019
1 Read

[Mycobacterium marinum as a cause of human and animal infections].

Klin Mikrobiol Infekc Lek 2018 Dec;24(4):112-117

Veterinary Research Institute, Brno, Czech Republic, e-mail:

Mycobacterium marinum is a slowly growing non-tuberculous (environmental, atypical) mycobacterium with zoonotic potential. It occurs in the aquatic environment and causes diseases in fish and other aquatic animals known as mycobacterioses. In humans, it primarily causes skin infections, which are most commonly located in the upper limbs. Read More

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December 2018
2 Reads

Clinical features of Mycobacterium canettii infection: a retrospective study of 20 cases among French soldiers and relatives.

Clin Infect Dis 2019 Feb 7. Epub 2019 Feb 7.

Department of Biology, Percy Military Teaching Hospital, Clamart, France.

Background: Mycobacterium canettii forms part of the Mycobacterium tuberculosis complex. M. canettii infections are mainly described in the Horn of Africa. Read More

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http://dx.doi.org/10.1093/cid/ciz107DOI Listing
February 2019
6 Reads

Mycobacterium fortuitum infection of a hemodialysis catheter in a pediatric patient.

Hemodial Int 2019 Feb 12. Epub 2019 Feb 12.

Pediatric Nephrology division, Children's Mercy Hospital, Kansas City, Missouri, USA.

This case report discusses a pediatric patient who developed a hemodialysis catheter line infection from an uncommon etiology, Mycobacterium fortuitum. The initial presentation revealed a well appearing patient with a slow growing skin lesion near the site of the hemodialysis catheter. The treatment course was complicated by resistance to initial antibiotics leading to continued spread of the lesion. Read More

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http://dx.doi.org/10.1111/hdi.12731DOI Listing
February 2019
1 Read

Tuberculosis of acromioclavicular joint: a case report.

BMC Infect Dis 2019 Feb 4;19(1):111. Epub 2019 Feb 4.

The First Clinical Medical College, Nanjing University of Chinese Medicine, No.138, Xianlin road, Qixia District, Nanjing, 210046, Jiangsu Province, China.

Background: Osteoarticular tuberculosis is a great masquerader presenting in varied forms and in atypical locations, and it is prone to misdiagnosis and missed diagnosis. Isolated acromioclavicular joint tuberculosis has been reported rarely.

Case Presentation: A 19-year-old man presented with a chronic, mild pain, non-healing ulcer in right shoulder. Read More

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12879-019-3760-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360657PMC
February 2019
9 Reads

Tuberculosis and atypical mycobacterial infections in ruxolitinib-treated patients with primary or secondary myelofibrosis or polycythemia vera.

Int J Infect Dis 2019 Mar 11;80:134-136. Epub 2019 Jan 11.

Department of Oncology and Haematology, Hôpitaux Universitaires de Strasbourg, Strasbourg, France; Université de Strasbourg, Inserm UMR-S1113/IRFAC, Strasbourg, France.

Ruxolitinib is a JAK-1/JAK-2 inhibitor indicated for the treatment of polycythemia vera and primary or secondary myelofibrosis. Only one patient (0.2%) was diagnosed with tuberculosis among the 485 patients receiving ruxolitinib in the four pivotal trials. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S12019712193001
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http://dx.doi.org/10.1016/j.ijid.2019.01.002DOI Listing
March 2019
16 Reads

Atypical rash.

Eur J Intern Med 2018 Dec 26. Epub 2018 Dec 26.

Infectious Diseases Section, Clinica Las Vegas, Medellín, Colombia.

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http://dx.doi.org/10.1016/j.ejim.2018.12.006DOI Listing
December 2018
3 Reads

Curious case of fever of unknown origin.

BMJ Case Rep 2018 Dec 3;11(1). Epub 2018 Dec 3.

Professor, Department of Medicine, All India Institute of Medical Sciences, New Delhi.

A 58-year-old immunocompetent woman presented with fever and significant weight loss of 4-month duration. She had mild pallor; rest of the examination was unremarkable. Investigations revealed anaemia with raised inflammatory markers. Read More

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http://dx.doi.org/10.1136/bcr-2018-227258DOI Listing
December 2018
2 Reads

Drug Susceptibility of Non-tuberculous Strains of Isolated from Birds from Poland.

Pol J Microbiol 2018 ;67(4):487-492

Department of Pathology and Veterinary Diagnostics, Warsaw University of Life Sciences , Warsaw , Poland.

Mycobacterioses are a constant problem in backyard poultry, as well as pet birds. To date, no evidence of direct transmission of atypical bacilli between humans has been demonstrated, but it cannot be ruled out that sick animals can be a source of infection for people in their environment. The aim of the study was to identify mycobacteria isolated from birds with diagnosed mycobacteriosis and to determine the susceptibility of mycobacterial isolates from these animals to antituberculous drugs most commonly used in the treatment of mycobacterial infections in humans. Read More

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https://www.exeley.com/polish_journal_of_microbiology/doi/10
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http://dx.doi.org/10.21307/pjm-2018-057DOI Listing
January 2018
14 Reads

The association between computed tomography scan findings of pulmonary infection caused by atypical mycobacteria and bacillus count in sputum samples.

Int J Mycobacteriol 2018 Oct-Dec;7(4):355-357

Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Disease, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: The use of imaging techniques is important for prompt diagnosis and treatment of atypical mycobacterial infections; it also reduces the burden of these infections. The purpose of the present study was to determine the association between computed tomography (CT) scan findings of pulmonary infection caused by atypical mycobacteria and bacillus count in sputum samples.

Methods: This cross-sectional, observational, comparative study included 50 consecutive patients with pulmonary infection caused by atypical mycobacteria, who were hospitalized in Masih-Daneshvari Hospital of Tehran, Iran during 2012-2017. Read More

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http://dx.doi.org/10.4103/ijmy.ijmy_139_18DOI Listing
December 2018
3 Reads

Mycobacterial Tenosynovitis After Sea Urchin Spine Injury in an Immunocompromised Patient.

Open Forum Infect Dis 2018 Nov 2;5(11):ofy285. Epub 2018 Nov 2.

Department of Surgery, Plastic Surgery Section, Louis Stokes Cleveland Veterans Affairs Medical Center, Ohio.

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https://academic.oup.com/ofid/advance-article/doi/10.1093/of
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http://dx.doi.org/10.1093/ofid/ofy285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262115PMC
November 2018
23 Reads

Tuberculous coxitis with trochanteric bursitis manifesting a year after immigration to Germany: a case report.

J Med Case Rep 2018 Nov 7;12(1):332. Epub 2018 Nov 7.

Hannover Medical University, Clinic for Immunology and Rheumatology, Carl-Neubergstr. 1, 30625, Hannover, Germany.

Background: Osteoarticular tuberculosis is rare in Germany. In particular, trochanteric bursitis is an extremely rare manifestation of osteoarticular tuberculosis. We describe a case of tuberculous coxitis with trochanteric bursitis, successfully treated with a fourfold tuberculostatic therapy. Read More

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https://jmedicalcasereports.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s13256-018-1867-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220512PMC
November 2018
21 Reads

A Case of Generalized, Superinfected Dermatitis and Inguinal Mycobacterium Lymphadenitis - TB or not TB?

Acta Dermatovenerol Croat 2018 Oct;26(3):270-272

Gyula Laszlo Fekete, MD, Bdul. 1 Decembrie 1918, no. 211/27, Tg. Mures, Romania:

Dear Editor, Eczema is an inflammatory dermatitis mediated by cellular immunity, with an etiology in which environmental, immunological, and genetic factors are involved. Skin inflammation through proinflammatory cytokines creates a favorable environment for microbial antigens and optimal conditions for infection (1). In case of underlying immunosuppression, inflammatory features of dermatitis and superimposed infections are more severe. Read More

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October 2018
25 Reads

Surgical Site Infections due to Non-Tuberculous Mycobacteria.

JNMA J Nepal Med Assoc 2018 Mar-Apr;56(211):696-700

Department of General Surgery, Nobel Medical College, Biratnagar, Morang, Nepal.

Introduction: Non-tuberculous Mycobacteria are increasingly recognized, nowadays as an important pathogen in delayed surgical site infection in post operative cases. We here in describe cases of surgical site infection caused by Non-tuberculous Mycobacteria, seen in two centers in Jhapa. The aim of the study was to increase awareness of this atypical mycobacterial infection, prompt diagnosis, and treatment that may ultimately provide better care to patients. Read More

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November 2018

The Mycobacterial Cell Envelope: A Relict From the Past or the Result of Recent Evolution?

Front Microbiol 2018 9;9:2341. Epub 2018 Oct 9.

INRS-Institut Armand-Frappier, Bacterial Symbionts Evolution, Laval, QC, Canada.

Mycobacteria are well known for their taxonomic diversity, their impact on global health, and for their atypical cell wall and envelope. In addition to a cytoplasmic membrane and a peptidoglycan layer, the cell envelope of members of the order , which include , also have an arabinogalactan layer connecting the peptidoglycan to an outer membrane, the so-called "mycomembrane." This unusual cell envelope composition of mycobacteria is of prime importance for several physiological processes such as protection from external stresses and for virulence. Read More

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http://dx.doi.org/10.3389/fmicb.2018.02341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194230PMC
October 2018
2 Reads

Cutaneous Infection With Mycobacterium haemophilum in an Immunocompromised Patient.

Iran J Kidney Dis 2018 Oct;12(5):312-314

Infectious Diseases and Tropical Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Mycobacterium haemophilum is a fastidious nontuberculosis Mycobacterium that must be considered in the differential diagnosis of infections in immunocompromised patients. Mycobacterium haemophilum typically is a pathogen of the cutaneous or subcutaneous tissue and also presents as septic arthritis, osteomyelitis, pulmonary disease, and lymphadenitis. We report a 32-year-old man with past medical history of kidney transplantation, endocarditis, gastrointestinal bleeding, and hypertension, complaining of multiple painful nodular lesions since 3 months earlier. Read More

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October 2018
23 Reads

Lymphadenitis by non-tuberculous mycobacteria in children.

Pediatr Int 2018 Dec 10;60(12):1062-1067. Epub 2018 Dec 10.

Department of Paediatrics, Archbishop Makarios III Hospital, Nicosia, Cyprus.

Background: Non-tuberculous mycobacteria (NTM) constitute an important cause of cervical lymphadenitis in immunocompetent children. The aims of this study were to estimate the incidence of lymphadenitis due to NTM in children in Cyprus and to describe the characteristics, diagnostic approach, management and outcome of such infections.

Methods: Children aged 1-5 years old, evaluated at Archbishop Makarios III Hospital, Nicosia, Cyprus, from 1 January 2007 to 31 December 2016 for lymphadenopathy, were included in the study. Read More

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http://dx.doi.org/10.1111/ped.13708DOI Listing
December 2018
7 Reads

Immunological correlates of mycobacterial growth inhibition describe a spectrum of tuberculosis infection.

Sci Rep 2018 Sep 27;8(1):14480. Epub 2018 Sep 27.

The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

A major contribution to the burden of Tuberculosis (TB) comes from latent Mycobacterium tuberculosis infections (LTBI) becoming clinically active. TB and LTBI probably exist as a spectrum and currently there are no correlates available to identify individuals with LTBI most at risk of developing active disease. We set out to identify immune parameters associated with ex vivo mycobacterial growth control among individuals with active TB disease or LTBI to define the spectrum of TB infection. Read More

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http://dx.doi.org/10.1038/s41598-018-32755-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160428PMC
September 2018
14 Reads

A Rare Catch in a Nonhealing Wound.

Wounds 2018 Sep;30(9):E87-E88

Houston Methodist Hospital, Houston, TX.

Introduction: Mycobacterium smegmatis is a common microbe found in soil, dust, and water that rarely causes infections in humans.

Case Report: A 45-year-old man with a past medical history of hypertension presented with a nonhealing surgical wound in his anterior chest wall, measuring 0.5 cm x 0. Read More

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September 2018
21 Reads

Mycobacterium abscessus infection in a spa worker.

Acta Dermatovenerol Alp Pannonica Adriat 2018 Sep;27(3):159-160

Department of Dermatology and Venereology, Centro Hospitalar São João, EPE, Porto, Portugal.

Mycobacterium abscessus (M. abscessus) is a non-tuberculous mycobacterium widely present in the natural environment and is now being increasingly identified as a cause of human disease. However, it can cause skin and soft tissue infection following trauma or surgery. Read More

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September 2018
3 Reads

Atypical serious hematochezia and rare imaging feature in gastrointestinal tuberculosis.

Clin J Gastroenterol 2019 Apr 19;12(2):182-188. Epub 2018 Sep 19.

Department of gastroenterology, Peking University First Hospital, No. 7th, Xishiku Street, Xicheng District, Beijing, 100034, China.

A young patient had serious hematochezia for nearly 2 months without obvious cause. Abdominal CT images showed rare features such as serious hemorrhage and multiple miliary nodules in the small bowel. The colonoscopy showed multiple lymphoid follicles in the terminal ileum. Read More

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http://dx.doi.org/10.1007/s12328-018-0910-0DOI Listing
April 2019
4 Reads

Inflammatory Reactions to Red Tattoo Inks: Three cases highlighting an emerging problem.

Sultan Qaboos Univ Med J 2018 May 9;18(2):e215-e218. Epub 2018 Sep 9.

Department of Dermatology, Hospital Universitario Campus de la Salud, Granada, Spain.

In recent years, tattoos have become more commonplace. However, this can result in various inflammatory processes, the management of which can be challenging in daily clinical practice. Tattoo-related inflammatory reactions can comprise different patterns, including acute and immediate reactions, foreign body granulomas, sarcoid granulomas, isomorphic lesions, allergic contact dermatitis and photosensitivity. Read More

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https://journals.squ.edu.om/index.php/squmj/article/view/272
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http://dx.doi.org/10.18295/squmj.2018.18.02.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132509PMC
May 2018
6 Reads

Hypercalcemia-induced acute kidney injury in a Caucasian female due to radiographically silent systemic sarcoidosis.

Clin Nephrol Case Stud 2018 4;6:21-26. Epub 2018 Sep 4.

Division of Nephrology.

. Sarcoidosis is a rare autoimmune disease resulting in formation of non-necrotizing "non-caseating" granulomas generally in the lung. The disease classically strikes African American females in their fourth and fifth decades. Read More

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http://dx.doi.org/10.5414/CNCS109513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125993PMC
September 2018
5 Reads

Therapeutic implications of nano-encapsulated rifabutin, azithromycin & ethambutol against experimental infection in mice.

Indian J Med Res 2018 06;147(6):594-602

Department of Biochemistry, Postgraduate Institute of Medical Education & Research, Chandigarh, India.

Background & Objectives: Mycobacterium avium causes atypical infection in both immunocompetent and immunocompromised individuals. Conventional chemotherapy for M. avium infection is not efficient due to lengthy course of treatment and drug-associated toxic side effects. Read More

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http://www.ijmr.org.in/text.asp?2018/147/6/594/239930
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http://dx.doi.org/10.4103/ijmr.IJMR_2004_15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118139PMC
June 2018
19 Reads
1.660 Impact Factor

Extrapulmonary tuberculosis: atypical presentation in otorhinolaryngology.

BMJ Case Rep 2018 Aug 29;2018. Epub 2018 Aug 29.

ENT, Head and Neck Surgery, Sri Ramachandra University Medical College, Chennai, Tamil Nadu, India.

Tuberculosis (TB) continues to be a major health burden globally more so in low/middle-income countries like India. There is an increase in the prevalence of extrapulmonary TB (EPTB) because of HIV epidemics and increased usage of immunomodulating drugs. EPTB constitutes 15%-20% of all patients with TB and >50% of HIV-TB coinfected patients. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22480
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http://dx.doi.org/10.1136/bcr-2018-224802DOI Listing
August 2018
18 Reads

Cutaneous atypical mycobacteriosis with sporotrichoid clinical presentation caused by automotive accident.

An Bras Dermatol 2018 Sep-Oct;93(5):743-745

Infectious Diseases Clinic, Hospital da Santa Casa de São Paulo, São Paulo (SP), Brazil.

Atypical mycobacterial infections are caused by mycobacteria other than those from the M. tuberculosis complex and M. leprae. Read More

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S
Publisher Site
http://dx.doi.org/10.1590/abd1806-4841.20187586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106664PMC
October 2018
21 Reads

Delayed diagnosis of extrapulmonary tuberculosis presenting as fever of unknown origin in an intermediate-burden country.

BMC Infect Dis 2018 Aug 28;18(1):426. Epub 2018 Aug 28.

Department of Internal Medicine, Boramae Medical Center, 20, Boramae-ro 5-gil, Dongjak-gu, Seoul, 07061, South Korea.

Background: Tuberculosis (TB), especially extrapulmonary tuberculosis (EPTB), is an important cause of fever of unknown origin (FUO) in TB-burdened areas. Little information is known about patients with EPTB with clinical features presenting as FUO and about the factor of delaying the diagnosis.

Methods: We retrospectively analyzed EPTB patients who were referred with FUO at 3 university-affiliated hospitals over 8 years (2010-2017). Read More

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http://dx.doi.org/10.1186/s12879-018-3349-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114835PMC
August 2018
6 Reads

Emerging and re-emerging infectious disease in otorhinolaryngology.

Acta Otorhinolaryngol Ital 2018 Apr;38(SUPPL. 1):S1-S106

SOC Neuroanestesia e Rianimazione, A.O.U. Careggi, Firenze, Italy.

Summary: Emerging and re-emerging infectious disease in otorhinolaryngology (ENT) are an area of growing epidemiological and clinical interest. The aim of this section is to comprehensively report on the epidemiology of key infectious disease in otorhinolaryngology, reporting on their burden at the national and international level, expanding of the need of promoting and implementing preventive interventions, and the rationale of applying evidence-based, effective and cost- effective diagnostic, curative and preventive approaches. In particular, we focus on i) ENT viral infections (HIV, Epstein-Barr virus, Human Papilloma virus), retrieving the available evidence on their oncogenic potential; ii) typical and atypical mycobacteria infections; iii) non-specific granulomatous lymphadenopathy; iv) emerging paediatric ENT infectious diseases and the prevention of their complications; v) the growing burden of antimicrobial resistance in ENT and the strategies for its control in different clinical settings. Read More

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http://www.actaitalica.it/issues/2018/2-2018S1/Suppl._Relazi
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056203PMC
http://dx.doi.org/10.14639/0392-100X-suppl.1-38-2018DOI Listing
April 2018
5 Reads

Endobronchial Non-Tuberculosis Mycobacterium Infection Presenting in a Healthy Child.

Ann Otol Rhinol Laryngol 2018 Oct 2;127(10):726-730. Epub 2018 Jul 2.

2 Department of Otolaryngology, Children's Mercy Hospital, Kansas City, Missouri, USA.

Objectives: To describe a safe and effective treatment for endobronchial Mycobacterium avium complex.

Methods: Case report and literature review.

Results: We present a case of endobronchial M. Read More

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http://dx.doi.org/10.1177/0003489418784970DOI Listing
October 2018
7 Reads

The Child with Recurrent Mycobacterial Disease.

Curr Allergy Asthma Rep 2018 Jun 23;18(8):44. Epub 2018 Jun 23.

Department of Pediatrics, Allergy-Immunology and Pediatric Rheumatology Division, Medical College of Georgia at Augusta University, 1120 15th Street, Augusta, GA, 30912, USA.

Purpose Of Review: Many genetic conditions predispose affected individuals to opportunistic infections. A number of immunodeficiency diseases, including genetic defects termed Mendelian susceptibility to mycobacterial disease (MSMD), permit infection from many different strains of mycobacteria that would otherwise not cause disease. These include tuberculous and nontuberculous mycobacteria, and bacille Calmette-Guérin vaccine (BCG). Read More

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http://dx.doi.org/10.1007/s11882-018-0797-3DOI Listing
June 2018
14 Reads

Erythema nodosum leprosum presenting as sweet's syndrome-like reaction in a borderline lepromatous leprosy patient.

Int J Mycobacteriol 2018 Apr-Jun;7(2):191-194

Department of Pathological Anatomy, Faculty of Medicine, Udayana University, Sanglah General Hospital, Denpasar, Indonesia.

Erythema nodosum leprosum (ENL) is characterized by tender erythematous nodules, accompanied by fever, malaise, arthralgia, and systemic complications. Atypical clinical manifestations have been reported such as pustular, bullous, ulceration; livedo reticularis; erythema multiforme-like reaction; and Sweet's syndrome (SS)-like presentation. We reported a case of ENL reaction presenting as SS-like reaction in a borderline lepromatous leprosy patient. Read More

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http://dx.doi.org/10.4103/ijmy.ijmy_49_18DOI Listing
March 2019
1 Read

Positive outcome of pulmonary tuberculosis associated with extraordinary extensive extrapulmonary tuberculosis in an immunocompetent adult.

Int J Mycobacteriol 2018 Apr-Jun;7(2):183-185

Department of Microbiology, Institute of Medical Science, BHU, Varanasi, Uttar Pradesh, India.

Tuberculosis (TB) is known to cause a wide variety of complications and atypical presentations. It usually presents with typical symptoms. Here, we present the unusual case of pulmonary TB with the involvement of lungs, brain, liver, spleen, vertebra, skin, left cervical lymph nodes, bone marrow, and heart. Read More

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http://dx.doi.org/10.4103/ijmy.ijmy_61_18DOI Listing
March 2019
4 Reads

complex: Natural history and treatment outcomes at a tertiary adult cystic fibrosis center.

Int J Mycobacteriol 2018 Apr-Jun;7(2):109-116

Infectious Diseases Unit, Alfred Hospital; Department of Medicine, Monash University, Melbourne, Victoria, Australia.

Background: Mycobacterium abscessus complex (MAbsC) is a significant management dilemma when taking care of patients with cystic fibrosis (CF).

Methods: We undertook a retrospective cohort analysis of all CF patients in whom MAbsC was isolated from 2005 to 2014. The natural history of MAbsC was determined and clinical factors examined in an attempt to predict transient compared to persistent colonization. Read More

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http://dx.doi.org/10.4103/ijmy.ijmy_55_18DOI Listing
March 2019
4 Reads

A study of a pancreatic mass: not all is what it seems.

Rev Esp Enferm Dig 2018 07;110(7):470-471

Gastroenterología y Hepatología, Hospital Universitario la Paz.

We report the case of a male with no medical history with acute cholangitis secondary to a pancreatic head´s mass suggestive of neoplasm. An EUS-FNA was performed where no atypical cells were identified but a granulomatous component did. The patient was finally diagnosed of disseminated tuberculosis with pancreatic involvement. Read More

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http://dx.doi.org/10.17235/reed.2018.5527/2018DOI Listing
July 2018
1 Read

The domain architecture of PtkA, the first tyrosine kinase from , differs from the conventional kinase architecture.

J Biol Chem 2018 07 8;293(30):11823-11836. Epub 2018 Jun 8.

From the Institute for Organic Chemistry and Chemical Biology, Centre for Biomolecular Magnetic Resonance (BMRZ), Goethe-University Frankfurt am Main, Max-von-Laue-Strasse 7, D-60438 Frankfurt am Main, Germany

The discovery that MptpA (low-molecular-weight protein tyrosine phosphatase A) from () has an essential role for virulence has motivated research of tyrosine-specific phosphorylation in and other pathogenic bacteria. The phosphatase activity of MptpA is regulated via phosphorylation on Tyr and Tyr Thus far, only a single tyrosine-specific kinase, protein-tyrosine kinase A (PtkA), encoded by the gene has been identified within the genome. MptpA undergoes phosphorylation by PtkA. Read More

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http://dx.doi.org/10.1074/jbc.RA117.000120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066317PMC
July 2018
18 Reads
4.573 Impact Factor

Risk factors and variations in detection of new bovine tuberculosis breakdowns via slaughterhouse surveillance in Great Britain.

PLoS One 2018 8;13(6):e0198760. Epub 2018 Jun 8.

Disease Dynamics Unit, Department of Veterinary Medicine, University of Cambridge, Cambridge, Cambridgeshire, United Kingdom.

Slaughterhouse surveillance through post-mortem meat inspection provides an important mechanism for detecting bovine tuberculosis (bTB) infections in cattle herds in Great Britain (GB), complementary to the live animal skin test based programme. We explore patterns in the numbers of herd breakdowns detected through slaughterhouse surveillance and develop a Bayesian hierarchical regression model to assess the associations of animal-level factors with the odds of an infected animal being detected in the slaughterhouse, allowing us to highlight slaughterhouses that show atypical patterns of detection. The analyses demonstrate that the numbers and proportions of breakdowns detected in slaughterhouses increased in GB over the period of study (1998-2013). Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0198760PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993271PMC
January 2019
23 Reads

Tenosynovitis with Rice Body Formation Due to Mycobacterium Intracellulare Infection After Initiation of Infliximab Therapy.

Am J Case Rep 2018 Jun 7;19:656-662. Epub 2018 Jun 7.

Department of Respiratory Medicine, Kyorin University School of Medicine, Mitaka, Tokyo, Japan.

BACKGROUND Rheumatoid arthritis tenosynovitis is difficult to discriminate from non-tuberculous tenosynovitis on the basis of radiological and pathological findings. CASE REPORT A 74-year-old woman with a 4-year history of rheumatoid arthritis was referred to our hospital to undergo treatment for uncontrollable tenderness and swelling in her right third metacarpophalangeal joint, right wrist, and left knee joint. In the previous year, she underwent surgery at a local hospital for the swelling in her right metacarpophalangeal joint, the information of which was not known precisely, but the swelling subsided in due course after an operation. Read More

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http://dx.doi.org/10.12659/AJCR.908785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020799PMC
June 2018
4 Reads

Disseminated mycobacteriosis caused by Mycobacterium kansasii in a pot-bellied pig.

J Vet Diagn Invest 2018 Jul 1;30(4):646-650. Epub 2018 Jun 1.

Indiana Animal Disease Diagnostic Laboratory and the Departments of Comparative Pathobiology (Schafbuch, Ramos-Vara), College of Veterinary Medicine, Purdue University, West Lafayette, IN.

A 1.5-y-old spayed female Juliana pot-bellied pig was presented to the Purdue University Veterinary Teaching Hospital with a history of wasting and anorexia. Enlarged and partially mineralized lymph nodes were identified on radiographs and computed tomography scan. Read More

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http://dx.doi.org/10.1177/1040638718780189DOI Listing
July 2018
1 Read

Cutaneous squamous cell carcinoma, thyroid cancer and Langerhans cell histiocytosis in a patient with X-linked recessive Mendelian susceptibility to mycobacterial diseases with a nuclear factor-κB essential modifier mutation.

J Dermatol 2018 Aug 24;45(8):1017-1019. Epub 2018 May 24.

Department of Dermatology, Gunma University Graduate School of Medicine, Maebashi, Japan.

Nuclear factor (NF)-κB essential modifier (NEMO), also known as IκB kinase subunit-γ (IKKγ), is a pivotal molecule in the NF-κB signaling pathway. Mutations of NEMO cause incontinentia pigmenti and X-linked ectodermal dysplasia with immunodeficiency. Mendelian susceptibility to mycobacterial diseases (MSMD), which confers an almost selective predisposition to mycobacterial infection, is also caused by NEMO mutations. Read More

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http://doi.wiley.com/10.1111/1346-8138.14482
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http://dx.doi.org/10.1111/1346-8138.14482DOI Listing
August 2018
10 Reads

Autosomal Dominant IFN-γR1 Deficiency Presenting with both Atypical Mycobacteriosis and Tuberculosis in a BCG-Vaccinated South African Patient.

J Clin Immunol 2018 May 18;38(4):460-463. Epub 2018 May 18.

DST/NRF Centre of Excellence for Biomedical Tuberculosis Research; South African Medical Research Council Centre for Tuberculosis Research; Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 241, 8000, Francie van Zijl Drive, Tygerberg, Cape Town, 7505, South Africa.

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http://link.springer.com/10.1007/s10875-018-0509-8
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http://dx.doi.org/10.1007/s10875-018-0509-8DOI Listing
May 2018
23 Reads

[Non-tuberculous mycobacterial cervical adenitis in children: 2 cases].

Ann Dermatol Venereol 2018 Aug - Sep;145(8-9):505-511

Service de dermatologie, CHU d'Angers, 4, rue Larrey, 49100 Angers, France.

Background: Cervical lymphadenitis is the most common manifestation of infection with nontuberculous mycobacteria (NTM) in immunocompetent children. Nevertheless, it is poorly known by dermatologists. Its incidence, which is currently increasing since the cessation of BCG vaccination in 2007, raises several issues regarding its pathophysiology, diagnosis and management. Read More

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http://dx.doi.org/10.1016/j.annder.2018.02.018DOI Listing
February 2019
4 Reads

An atypical infection of the esophagus mimicking malignancy.

Gastrointest Endosc 2018 10 21;88(4):765-766. Epub 2018 Jun 21.

Department of Internal Medicine, Far Eastern Memorial Hospital, Ban-Ciao, New Taipei City, Taiwan, Republic of China; College of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan, Republic of China.

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http://dx.doi.org/10.1016/j.gie.2018.05.007DOI Listing
October 2018
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Tuberculous peritonitis and pleurisy accompanied by pulmonary cryptococcosis: A case report.

J Int Med Res 2018 Jul 13;46(7):2976-2982. Epub 2018 May 13.

The Third Comprehensive Department, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou, Guangdong 510006, China.

Although the infectious diseases tuberculosis (TB) and cryptococcosis both cause formation of single or multiple nodules in immunodeficient hosts, cases of co-infection of these diseases are rarely seen. We report a patient who was co-infected with TB and cryptococcosis. A male patient with no clinical evidence of immunodeficiency presented with a 3-week history of abdominal distension accompanied by oedema of recurring lower extremities. Read More

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http://dx.doi.org/10.1177/0300060518773239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124282PMC
July 2018
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Pulmonary Mycobacterial Spindle Cell Pseudotumor: A Report of 3 Cases Including a Practical Approach to Histopathologic Recognition of This Unusual Entity.

Int J Surg Pathol 2018 Oct 2;26(7):629-634. Epub 2018 May 2.

1 Department of Pathology, University of Utah School of Medicine and Associated Regional and University Pathologists Laboratories, Salt Lake City, UT, USA.

Mycobacterial spindle cell pseudotumor (MSP) is a rare benign spindle cell lesion containing acid-fact mycobacteria. These lesions are most commonly identified in the lymph nodes, skin, spleen, or bone marrow of immunocompromised patients and only rarely involve the lungs. We report 3 cases of pulmonary MSP, which include 2 patients who are known to be HIV-positive. Read More

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http://dx.doi.org/10.1177/1066896918770010DOI Listing
October 2018
9 Reads

Incidental intraoperative diagnosis of Mycobacterium abscessus meningeal infection: a case report and review of the literature.

Infection 2018 Oct 23;46(5):591-597. Epub 2018 Apr 23.

Department of Neurosurgery, Catholic University of Rome, Largo A. Gemelli 8, 00168, Rome, Italy.

Purpose: Mycobacterium abscessus, and rapidly growing mycobacteria in general, are rare but increasing causes of central nervous system (CNS) infections. The aim of this study is to highlight the importance of considering these microorganism in the differential diagnosis of CNS infections, obtaining a prompt diagnosis, and improving clinical outcomes.

Methods: Case report and literature review. Read More

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http://dx.doi.org/10.1007/s15010-018-1141-5DOI Listing
October 2018
10 Reads