3,706 results match your criteria Atypical Mycobacterial Diseases


Chest wall tuberculosis in children: a mimicker of bone tumour.

BMJ Case Rep 2021 Apr 22;14(4). Epub 2021 Apr 22.

Department of Radiodiagnosis, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Osteoarticular tuberculosis of flat bones of the chest wall such as sternum, scapula and rib is extremely rare in children. Because of its atypical clinical presentation mimicking malignant bone tumours, diagnosis remains a challenge. Histological and microbiological diagnosis remains confirmatory. Read More

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Chronic Mycobacterium kansasii tenosynovitis in an immunocompromised host : case report.

Acta Orthop Belg 2020 Dec;86(4):621-623

Mycobacteriuim kansasii is a nontuberculous atypical mycobacterium which typically causes respiratory infections. Localized extrapulmonary diseases, such as tenosynovitis or arthritis are rarely seen in the immunocompetent population (1) . We present a case of an immunocompromised 55-year-old man with a chronic Mycobacteriuim kansasii tenosynovitis of the hand. Read More

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December 2020

Paragonimus infection: Rare manifestation with pericardial effusion: A Case report and Literature review.

IDCases 2021 16;24:e01075. Epub 2021 Mar 16.

Hamad Medical Corporation, Department of Internal Medicine - Division of Infectious Diseases, Qatar.

Background: Paragonimus, is a globally distributed trematode, with human disease limited to endemic regions. It can be transmitted to humans through ingestion of intermediate hosts that are crustaceans. Most symptomatic infections consist of pulmonary disease, and in aberrant migration of immature flukes, extrapulmonary manifestations may occur. Read More

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Histopathology of laboratory-reared Nothobranchius fishes: Mycobacterial infections versus neoplastic lesions.

J Fish Dis 2021 Apr 12. Epub 2021 Apr 12.

Department of Botany and Zoology, Faculty of Science, Masaryk University, Brno, Czech Republic.

Short-lived killifishes of the genus Nothobranchius Peters, 1868 (Cyprinodontiformes) are considered promising model organisms for biomedical research on ageing and tumorigenesis. We conducted histopathological analysis of 411 adult individuals from three Nothobranchius species to study details on spontaneous age-related neoplastic lesions. Light microscopy based on H&E and toluidine blue-stained sections revealed (a) non-proliferative liver changes with pronounced vacuolation of hepatocytes; (b) proliferation of kidney haemopoietic tissue contributing to excretory system damage; (c) proliferation of splenic mononuclear haemoblasts accompanied by reduced erythropoiesis; (d) proliferation of mononuclear cell aggregates in the liver parenchyma; and (e) rare occurrence of hepatocellular adenomas. Read More

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Tuberculosis Septic Arthritis of the Elbow: A Case Report and Literature Review.

Cureus 2021 Mar 8;13(3):e13765. Epub 2021 Mar 8.

Department of Orthopedics, Prince of Songkhla University, Songkhla, THA.

Tuberculosis (TB) infections of the musculoskeletal system are rare. A 77-year-old female with chronic left elbow pain for five months was treated by irrigation and debridement of the elbow for a presumed diagnosis of septic arthritis. Her pain and wound condition did not improve, and she was referred to our institution. Read More

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Simultaneous catheter removal and reinsertion, is it acceptable in M. abscessus exit site infection?

CEN Case Rep 2021 Mar 16. Epub 2021 Mar 16.

North Florida/South Georgia Veteran Healthcare System, Gainesville, FL, USA.

In recent times, increasing reports of exit site infections (ESI) in peritoneal dialysis (PD) patients related to environmentally acquired atypical organisms, such as nontuberculous mycobacterium (NTM), have been reported in the literature. Among these NTM, Mycobacterium abscessus (M. abscessus) is unique and is associated with high morbidity and treatment failure rates. Read More

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When to consider tuberculosis: bronchiectasis in the elderly population.

BMJ Case Rep 2021 Mar 4;14(3). Epub 2021 Mar 4.

Respiratory Medicine, Imperial College Healthcare NHS Trust, London, UK.

In England patients aged 65 years and over experience a delay of more than 4 months between onset of symptoms and diagnosis of pulmonary TB. This report examines three cases of patients experiencing significant delays in both diagnosis and treatment. Each case had a background of bronchiectasis. Read More

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Clinical and demographic study of non-tuberculous mycobacterial ocular infections in South India.

Indian J Med Microbiol 2021 Jan 7;39(1):41-47. Epub 2020 Nov 7.

Department of Cornea and Refractive Surgery Services, Aravind Eye Hospital, Madurai, Tamil Nadu, India.

Purpose: To describe demographics, risk factors, antibiotic susceptibility, management and outcomes of ocular infections caused by non-tuberculous mycobacteria (NTM).

Methods: A retrospective review of medical case records and microbiology records of patients with ocular infections that were culture positive for non-tuberculous Mycobacteria from January 2014 to December 2018 was done. Antibiotic susceptibility profile was done based on the CLSI guidelines. Read More

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January 2021

Gummatous cutaneous tuberculosis associated with the use of infliximab for Crohn's disease.

An Bras Dermatol 2021 Mar-Apr;96(2):228-230. Epub 2021 Jan 31.

Department of Gastroenterology, Faculty of Medicine, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.

As the treatment of infectious and parasitic diseases improved, the prevalence of these conditions declined. However, with the expansion of the use of immunobiologicals, opportunistic infections have emerged, especially under atypical presentations. The present study reports the case of a patient treated with infliximab for Crohn's disease, who presented diarrhea, weight loss, abdominal pain, fever, and subcutaneous erythematous nodules that evolved with spontaneous fluctuation and ulceration. Read More

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Sweet Syndrome precipitated by in a Laotian Man with Autoantibodies to Interferon Gamma.

J Investig Med High Impact Case Rep 2021 Jan-Dec;9:2324709621990771

University of Arkansas for Medical Sciences, Little Rock, AR, USA.

Autoantibodies to interferon γ, part of the first line of defense in the human immune response, constitutes a rare form of an acquired immunodeficiency in HIV-uninfected adults that can predispose to disseminated atypical mycobacterial infection. Particularly, this has been described in people of Southeast Asian origin. In this case report, we describe a previously healthy, Laotian man who presented with skin lesions consistent with Sweet syndrome that were later found to be precipitated by disseminated atypical mycobacterial disease. Read More

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February 2021

Bloodstream Infection Associated with a Totally Implanted Subclavian Port in an Adult with Diabetes and History of Colon Cancer.

Case Rep Infect Dis 2020 31;2020:8878069. Epub 2020 Dec 31.

Section of Infectious Diseases, Medical Service, Oklahoma City VA Medical Center, Department of Medicine, Oklahoma University Health Sciences Center, 921 NE 13th Street, Oklahoma City 73104, OK, USA.

. is a rapidly growing nontuberculosis mycobacterium (NTM) that was first isolated from soil in 1972 and is ubiquitous in soil, water, and dust. The first reported case of human infection by was published in 1988, presenting as a Hickman catheter-related bacteremia in a patient with ovarian cancer. Read More

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December 2020

Extensor Tenosynovitis due to Mycobacterium marseillense Infection in a Renal Transplant Recipient.

J Am Acad Orthop Surg Glob Res Rev 2021 01 12;5(1). Epub 2021 Jan 12.

From the Houston Methodist Orthopedic and Sports Medicine, Houston, TX.

Renal transplant recipients are at an increased risk of atypical nontuberculous mycobacterial (NTM) infections. Infections caused by NTM are uncommon in the general population, rarely occurring in immunocompetent individuals. NTM infections are an uncommon cause of tenosynovitis. Read More

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January 2021

Tuberculous perihepatic abscess and neurosarcoidosis: report of 2 uncommon manifestations of 2 common granulomatous diseases in 1 patient.

Z Gastroenterol 2021 Jan 11;59(1):50-55. Epub 2021 Jan 11.

Department of Medicine II, University Hospital, LMU Munich, Munich, Germany.

Infections caused by pathogens of the Mycobacterium tuberculosis complex, i. e., tuberculosis (TB), and the non-infectious, autoimmune disease sarcoidosis are among the most common granulomatous diseases worldwide. Read More

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January 2021

A Complication of Mycobacterium chelonae Infection Following Orbital Floor Fracture Repair.

J Craniofac Surg 2021 Jan 7;Publish Ahead of Print. Epub 2021 Jan 7.

University of North Carolina School of Medicine Department of Otolaryngology - Head and Neck Surgery, Division of Facial Plastic and Reconstructive Surgery Department of Otolaryngology - Head and Neck Surgery, Division of Voice and Swallowing Disorders, University of North Carolina, Chapel Hill, NC.

Abstract: Mycobacterium chelonae is a rare, atypical nontuberculous bacterium that has been reported to be an underlying cause of persistent wound infections. Although there are several studies highlighting the role of M chelonae as the putative cause of other postoperative wound infections, to our knowledge there are no reports of infection following implant placement for repair of an orbital floor fracture. The authors present a unique case describing the management of a persistent postoperative infection in a young, immunocompetent patient with an orbital floor fracture repaired with a Stryker Medpor Titan implant. Read More

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January 2021

A large verrucous plaque on the buttocks: a case report of an atypical presentation of tuberculosis verrucosa cutis.

Pan Afr Med J 2020 6;37:131. Epub 2020 Oct 6.

Dr. Wahidin Sudirohusodo Hospital, South Sulawesi, Makassar, Indonesia.

Although the incidence of cutaneous tuberculosis (TB) has declined among all cases in dermatology outpatient settings, atypical cases are still being reported worldwide. These atypical forms can imitate other conditions hence delaying the diagnosis and increased morbidity. We report a case of an atypical presentation of extensive Tuberculosis Verrucosa Cutis (TVC) on the buttocks presenting as an annular hyperkeratotic plaque with central healing. Read More

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January 2021

Cryptococcal fungemia and Mycobacterium haemophilum cellulitis in a patient receiving ruxolitinib: a case report and literature review.

BMC Infect Dis 2021 Jan 7;21(1):27. Epub 2021 Jan 7.

Division of Infectious Diseases and Tropical Medicine, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkoknoi, Bangkok, 10700, Thailand.

Background: Ruxolitinib is a novel oral Janus kinase inhibitor that is used for treatment of myeloproliferative diseases. It exhibits potent anti-inflammatory and immunosuppressive effects, and may increase the risk of opportunistic infections. Here, we report a rare case of Cryptococcus neoformans and Mycobacterium haemophilum coinfection in a myelofibrosis patient who was receiving ruxolitinib. Read More

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January 2021

Genome-wide identification of novel genes involved in Corynebacteriales cell envelope biogenesis using Corynebacterium glutamicum as a model.

PLoS One 2020 31;15(12):e0240497. Epub 2020 Dec 31.

Institute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, CEA, CNRS, Gif-sur-Yvette, France.

Corynebacteriales are Actinobacteria that possess an atypical didermic cell envelope. One of the principal features of this cell envelope is the presence of a large complex made up of peptidoglycan, arabinogalactan and mycolic acids. This covalent complex constitutes the backbone of the cell wall and supports an outer membrane, called mycomembrane in reference to the mycolic acids that are its major component. Read More

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January 2021

NLRC5 promotes transcription of genes and Vγ9Vδ2 T cell-mediated killing.

iScience 2021 Jan 7;24(1):101900. Epub 2020 Dec 7.

Università della Svizzera italiana (USI), Faculty of Biomedical Sciences, Institute for Research in Biomedicine, 6500 Bellinzona, Switzerland.

BTN3A molecules-BTN3A1 in particular-emerged as important mediators of Vγ9Vδ2 T cell activation by phosphoantigens. These metabolites can originate from infections, e.g. Read More

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January 2021

Feline mycobacterial disease in northern California: Epidemiology, clinical features, and antimicrobial susceptibility.

J Vet Intern Med 2021 Jan 21;35(1):273-283. Epub 2020 Dec 21.

Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, Davis, California, USA.

Background: Mycobacterial infections in cats are challenging to treat and incompletely described.

Hypothesis/objectives: To describe the features of mycobacterial infections in cats from northern California.

Animals: Nineteen cats, all with nontuberculous mycobacterial (NTM) infections; 4 with Mycobacterium avium infection, 15 with rapid-growing mycobacterial (RGM) infection. Read More

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January 2021

Mycobacterial identification on homogenised biopsy facilitates the early diagnosis and treatment of laryngeal tuberculosis.

Open Med (Wars) 2020 5;15(1):508-512. Epub 2020 Jun 5.

Department of Infectious Diseases, Taizhou Enze Medical Center (Group) Enze Hospital, No. 1, Tongyang Road, Taizhou 318000, Zhejiang, China.

Introduction: The incidence of laryngeal tuberculosis has increased gradually in recent years. Laryngeal tuberculosis has strong infectivity and atypical clinical manifestations. Hence, establishing the early diagnosis of laryngeal tuberculosis is considered difficult, resulting in the high rate of misdiagnosis of laryngeal tuberculosis and increased rates of tuberculosis infection. Read More

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[Clinical features of children with immunodeficiency and infection].

Zhongguo Dang Dai Er Ke Za Zhi 2020 Dec;22(12):1300-1305

Department of Child Infection, Children's Hospital of Chongqing Medical University/Ministry of Education Key Laboratory of Child Development and Disorders/National Clinical Research Center for Child Health and Disorders/China International Science and Technology Cooperation Base of Child Development and Critical Disorders/Chongqing Key Laboratory of Child Infection and Immunity, Chongqing 400014, China.

Objective: To study the clinical features of infection in children with secondary immunodeficiency disease (SID) versus primary immunodeficiency disease (PID).

Methods: A retrospective analysis was performed on the medical data of children with immunodeficiency and infection (36 children with SID and 52 with PID) and 108 children with infection but without immunodeficiency (control group).

Results: The onset age in the PID group was significantly lower than those in the control and SID groups ( < 0. Read More

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December 2020

Disseminated tuberculosis in children-a difficult diagnose depends on how far we can go.

BMJ Case Rep 2020 Dec 13;13(12). Epub 2020 Dec 13.

Pediatrics, All India Institute of Medical Sciences Jodphur, Jodhpur, Rajasthan, India.

Tuberculosis (TB) is an important public health problem in developing countries. In India, despite substantial efforts targeting TB and its associated risk factors, the number of cases remains high with 2.7 million new cases per year with a minimum 10% case contributed by paediatric TB. Read More

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December 2020

Infectious diseases in German military personnel after predominantly tropical deployments: a retrospective assessment over 13 years.

BMJ Mil Health 2020 Nov 30. Epub 2020 Nov 30.

Department of Microbiology and Hospital Hygiene, Bundeswehrkrankenhaus Hamburg, Hamburg, Germany

Objectives: Military deployments to the tropics are associated with specific infection risks. To add to the available epidemiological information, infectious disease risks in German military personnel returning from predominantly tropical deployments were assessed.

Methods: Since 2006, German soldiers returning from predominantly tropical deployments have been offered the opportunity of returnee screenings at the Department of Tropical Medicine and Infectious Diseases of the Bundeswehr Hospital Hamburg. Read More

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November 2020

Middle east tuberculosis in an immunocompromised patient: Case report and review of the literature.

J Infect Public Health 2021 Jan 21;14(1):139-142. Epub 2020 Nov 21.

Department for Otolaryngology and Head and Neck Surgery, Clinical Hospital Center Rijeka, Kresimirova 52, 51000 Rijeka, Croatia.

Tuberculosis is an airborne disease caused by Mycobacterium tuberculosis. In 15-20% cases of active disease extrapulmonary tuberculosis may occur, most commonly in the head and neck region. Tuberculous otitis media accounts for 0,1% of the total number of tuberculosis patients. Read More

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January 2021

Nontuberculous mycobacterial endophthalmitis: case series and review of literature.

BMC Infect Dis 2020 Nov 23;20(1):877. Epub 2020 Nov 23.

Department of Ophthalmology, Faculty of Medicine, Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkok Noi, Bangkok, 10700, Thailand.

Background: To report three cases of nontuberculous mycobacterial (NTM) endophthalmitis following multiple ocular surgeries and to review previous literature in order to study the clinical profile, treatment modalities, and visual outcomes among patients with NTM endophthalmitis.

Methods: Clinical manifestation and management of patients with NTM endophthalmitis in the Department of Ophthalmology, Faculty of Medicine, Siriraj hospital, Mahidol University, Bangkok, Thailand were described. In addition, a review of previously reported cases and case series from MEDLINE, EMBASE, and CENTRAL was performed. Read More

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November 2020

Diagnosis of nontuberculous mycobacterial lymphadenitis: the role of fine-needle aspiration.

Eur J Pediatr 2021 Apr 17;180(4):1279-1286. Epub 2020 Nov 17.

Pediatric Infectious Diseases Unit, Department of Pediatrics, Hospital Universitario 12 de Octubre, Universidad Complutense de Madrid, Avenida de Córdoba S/N, 28048, Madrid, Spain.

Nontuberculous mycobacterial lymphadenitis often presents a diagnostic challenge. This study aimed to evaluate the role of fine-needle aspiration cytology in the diagnosis of nontuberculous mycobacterial lymphadenitis in children. We conducted a retrospective review of fine-needle aspiration cytology performed in patients < 17 year-old with subacute lymphadenitis from 2003 to 2016 in a tertiary hospital in Spain. Read More

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Molecular epidemiology of isolates in Iran using spoligotyping.

New Microbes New Infect 2020 Nov 28;38:100767. Epub 2020 Sep 28.

Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Spoligotyping can help assess the transmission of strains. We aimed to study the genotyping of isolated from patients with tuberculosis from the west of Iran by spoligotyping. Forty-seven isolates were collected from the west of Iran. Read More

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November 2020

Corticosteroid-induced exacerbation of cryptic miliary tuberculosis to acute respiratory distress syndrome: A case report.

Medicine (Baltimore) 2020 Nov;99(46):e23204

Department of Radiology, Chungbuk National University Hospital.

Rationale: Steroid is known to cause generalized immunosuppression, thereby increasing the risk of new infection or recurrence of tuberculosis. However, corticosteroid as a culprit for exacerbation of miliary tuberculosis-from a cryptic to an overt form-has rarely been described in the literature. Moreover, miliary tuberculosis is hardly diagnosed in a living patient as a primary cause of ARDS even in TB-endemic regions. Read More

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November 2020

Total Knee Arthroplasty in Patients with Unsuspected Tuberculosis of the Joint: A Report of Four Cases and a Systematic Review of the Literature.

Orthop Surg 2020 Dec 4;12(6):1900-1912. Epub 2020 Nov 4.

Department of Joint Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.

Objectives: To provide a case series and systematic review that explores the clinical manifestations, treatments, and methods for defining tuberculosis diagnoses in patients who have undergone total knee arthroplasty (TKA).

Methods: Four patients (three women, one man; average age, 59.5 ± 8. Read More

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December 2020