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    3323 results match your criteria Atypical Mycobacterial Diseases

    1 OF 67

    Mycobacterial Arthritis and Synovitis in Painted Reed Frogs (Hyperolius marmoratus).
    J Comp Pathol 2017 Feb 20. Epub 2017 Feb 20.
    National Zoological Gardens of South Africa, Pretoria, South Africa.
    Several species of atypical mycobacteria have been isolated from wild and captive amphibians. In captive anurans, cutaneous and visceral mycobacteriosis are common and can result in significant mortality, particularly when animals are immunocompromised. Mycobacterial arthritis and synovitis are reported rarely in amphibians. Read More

    Molecular identification and distribution of Non-Tuberculous Mycobacteria isolated from clinical specimens by PCR-Sequencing method in west of Iran.
    Clin Respir J 2017 Feb 22. Epub 2017 Feb 22.
    Department of Microbiology, Faculty of Medicine, Kermanshah University of Medical Sciences, Shirudi Shahid Boulevard, Daneshgah Street, Kermanshah, 67148-69914, Iran.
    Background And Aims: Infections by Non-tuberculous Mycobacteria (NTM) has rapidly increased in recent years, due to high infection rates related to the populations at risk like immunocompromised individuals, patients predisposed by prior pulmonary. The aim of this study was to investigate the presence of NTM in clinical samples and genetic diversity using 16S rRNA and rpoB sequence analysis.

    Methods: A cross-sectional study was conducted on 45 diverse isolates collected from sputum in two years 2014-2015 using standard decontamination procedure. Read More

    Coexistent Sarcoidosis and Tuberculosis: A Case Report.
    Respiration 2017 Feb 9. Epub 2017 Feb 9.
    Department of Medical and Surgical Sciences, Institute of Respiratory Diseases, Azienda Ospedaliero Universitaria Foggia, Foggia, Italy.
    Necrotizing granulomatous diseases of the lungs are usually dependent on a narrow range of differential diagnoses. Tuberculosis (TB) is responsible for the largest number of cases, while necrotizing sarcoidosis is generally considered a rare and easily distinguishable disease substantially based on histological features. However, this entity has become a viable diagnosis in the absence of mycobacteria isolation or when a remarkable clinical improvement cannot be achieved with the combination of anti-TB drugs at full dosage. Read More

    Prospective etiological investigation of community-acquired pulmonary infections in hospitalized people living with HIV.
    Medicine (Baltimore) 2017 Jan;96(4):e5778
    aScientific Division, Instituto de Infectologia Emílio Ribas, São Paulo, SP, Brazil bDepartment of Medicine Solna, Infectious Diseases Unit, Karolinska Institutet cDepartment of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden dEmilio Ribas Institute of Infectious Diseases eDepartment of Infectious Diseases, University of São Paulo Medical School, São Paulo, SP, Brazil.
    The study of the etiological agents of community-acquired pulmonary infections is important to guide empirical therapy, requires constant updating, and has a substantial impact on the prognosis of patients. The objective of this study is to determine prospectively the etiology of community-acquired pulmonary infections in hospitalized adults living with HIV. Patients were submitted to an extended microbiological investigation that included molecular methods. Read More

    Atypical Mycobacterial Infection after Abdominoplasty Overseas: A Case Report and Literature Review.
    Case Rep Infect Dis 2016 27;2016:3642567. Epub 2016 Dec 27.
    Department of Infectious Diseases, Yale New Haven Health System, Bridgeport Hospital, Bridgeport, CT 06610, USA.
    Increasing number of medical tourists travel internationally for cosmetic procedures. Lipotourism is a form of medical tourism becoming popular among patients of developed countries due to the cost efficiency of cosmetic procedures when performed in developing nations. There is a paucity of data on quality, safety, and risks involved with these surgeries. Read More

    A Case of Surgical Site Infection Caused by Mycobacterium fortuitum, following Herniorrhaphy.
    J Clin Diagn Res 2016 Nov 1;10(11):DD01-DD02. Epub 2016 Nov 1.
    Associate Professor, Department of General Surgery, Indira Gandhi Medical College and Research Institute , Puducherry, India .
    Rapidly Growing Mycobacteria (RGM) are opportunistic pathogens found in the environment. Mycobacterium fortuitum, M. chelonae and M. Read More

    Mycobacterium haemophilum: A report of cutaneous Infection in a Patient with end-stage renal disease.
    Int J Mycobacteriol 2016 Dec 9;5 Suppl 1:S236. Epub 2016 Nov 9.
    Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address:
    Introduction: Mycobacterium haemophilum is a slow-growing nontuberculous mycobacterium (NTM) that can cause ulcerating cutaneous or subcutaneous nodular skin lesions in immunocompromised and immunocompetent patients. Acid-fast staining cannot distinguish NTM from M. tuberculosis; culturing at two temperatures with iron-supplemented media and polymerase chain reaction (PCR) are needed for optimal detection of M. Read More

    IL-12Rβ1 defect presenting with massive intraabdominal lymphadenopathy due to Mycobacterium intracellulare: A case report.
    Asian Pac J Allergy Immunol 2016 Dec 12. Epub 2016 Dec 12.
    Marmara University School of Medicine, Department of Pediatrics, Division of Pediatric Infectious Diseases, Istanbul, Turkey.
    Infections due to non-tuberculous mycobacteria species are problematic for immunodeficient individuals. Mendelian susceptibility to mycobacterial diseases (MSMD) defines a group of genetic defects affecting cellular interactions and the interferon (IFN)-γ pathway. Patients with MSMD may present with a disseminated infection resulting from the Bacillus Calmette-Guerin vaccine, Mycobacterium tuberculosis complex, environmental nontuberculous mycobacteria or Salmonella species. Read More

    Pulmonary Mycobacterium kansasii disease in immunocompetent host: Treatment outcomes with short-course chemotherapy.
    Indian J Med Microbiol 2016 Oct-Dec;34(4):516-519
    Department of Clinical Research, National Institute for Research in Tuberculosis, Chennai, Tamil Nadu, India.
    Mycobacterium kansasii, most virulent of all atypical mycobacteria, causes pulmonary disease identical to the disease caused by Mycobacterium tuberculosis. Early identification of the species and prompt initiation of treatment for M. kansasii is necessary to prevent morbidity and mortality due to this disease. Read More

    Clinical implications of Mycobacterium chimaera detection in thermoregulatory devices used for extracorporeal membrane oxygenation (ECMO), Germany, 2015 to 2016.
    Euro Surveill 2016 Nov;21(46)
    Institute of Medical Microbiology and Hygiene, Saarland University, Homburg/Saar, Germany.
    Mycobacterium chimaera, a non-tuberculous mycobacterium, was recently identified as causative agent of deep-seated infections in patients who had previously undergone open-chest cardiac surgery. Outbreak investigations suggested an aerosol-borne pathogen transmission originating from water contained in heater-cooler units (HCUs) used during cardiac surgery. Similar thermoregulatory devices are used for extracorporeal membrane oxygenation (ECMO) and M. Read More

    Novel Mutation of Interferon-γ Receptor 1 Gene Presenting as Early Life Mycobacterial Bronchial Disease.
    J Investig Med High Impact Case Rep 2016 Oct-Dec;4(4):2324709616675463. Epub 2016 Nov 8.
    Children's National Medical Center, Washington, DC, USA; George Washington University, Washington, DC, USA.
    Mendelian susceptibility to mycobacterial diseases (MSMD) are a spectrum of inherited disorders characterized by localized or disseminated infections caused by atypical mycobacteria. Interferon-γ receptor 1 (IFNGR1) deficiency was the first identified genetic disorder recognized as MSMD. Mutations in the genes encoding IFNGR1 can be recessive or dominant and cause complete or partial receptor deficiency. Read More

    Mycobacterium chelonae in a tectonic corneal graft.
    Oman J Ophthalmol 2016 Sep-Dec;9(3):177-178
    Sussex Eye Hospital, Brighton, East Sussex, BN2 5BF, UK.
    Atypical mycobacterial infections of the cornea can present with nonspecific inflammatory changes and graft rejection, with no obvious focus to culture and a subsequent delay to diagnosis. These pathogens are well documented in the literature following laser-assisted in situ keratomileusis but have rarely been described following corneal transplant surgery. We report a single case of Mycobacterium chelonae keratitis 1 year after tectonic keratoplasty. Read More

    Abdominal tuberculosis: an old disease surprising young doctors.
    BMJ Case Rep 2016 Nov 2;2016. Epub 2016 Nov 2.
    Department of Surgery-Cirurgia B, Hospital Professor Doutor Fernando Fonseca EPE, Amadora, Portugal.
    Tuberculosis remains a worldwide public health concern. Atypical extrapulmonary presentations may delay the diagnosis and treatment. We present the case of an adult woman admitted to the emergency department with bowel obstruction. Read More

    Tuberculous Fasciitis in Polymyositis: A Rare Case of Extrapulmonary Tuberculosis.
    Intern Med 2016;55(21):3205-3209. Epub 2016 Nov 1.
    Department of Nephrology, Osaka Rosai Hospital, Japan.
    A 71-year-old woman with polymyositis presenting with left thigh pain and an intermittent fever was admitted to Osaka Rosai Hospital. We initially diagnosed that her pain and fever were caused by a soft tissue infection because her polymyositis was controlled. She did not respond to various antibiotic therapies. Read More

    Hoarse voice: a rare presentation of tuberculosis lymphadenitis.
    BMJ Case Rep 2016 Oct 24;2016. Epub 2016 Oct 24.
    Imperial College Healthcare NHS Trust, London, UK.
    A man aged 37 years from Indian descent presented to an inner city London hospital with hoarseness of voice, fatigue, night sweats and a 2 kg weight loss. Laryngoscopy demonstrated a left vocal fold palsy. Extensive investigations were undertaken with disseminated malignancy being primarily investigated. Read More

    Mycobacterium avium Infection of Nasal Septum in a Diabetic Adult: A Case Report.
    Head Neck Pathol 2016 Dec 20;10(4):552-555. Epub 2016 Jun 20.
    Department of Pathology, Creighton University School of Medicine, Omaha, NE, USA.
    Mycobacterium avium complex (MAC) is primarily a pulmonary pathogen that affects individuals who are immune deficient or immunocompromised. In this report, we describe a very rare case of MAC infection clinically presenting as a nasal polyp in a patient with type 2 diabetes mellitus. This case illustrates an atypical anatomic location for MAC, the anterior nasal septum in nasal cavity, as well as often overlooked cause of immune compromise, diabetes mellitus. Read More

    Mycobacterium chelonae-abscessus Complex Infection After Flatfoot Reconstruction.
    J Foot Ankle Surg 2016 Nov - Dec;55(6):1327-1332. Epub 2016 Feb 24.
    Attending Surgeon, Inova Fairfax Hospital, Private Practice, Fairfax, VA.
    Mycobacterium infections involving tuberculosis in the foot are rare but cases are readily available in published studies. Atypical or nontuberculosis mycobacterium foot infections are rare, especially those involving the soft tissue and bone, and have been infrequently reported. To date, no case reports involving atypical mycobacterium infection after elective foot surgery have been reported. Read More

    Atypical imaging of spinal tuberculosis: a case report and review of literature.
    Pan Afr Med J 2016 31;24:101. Epub 2016 May 31.
    Department of Orthopedics, Xi'an Chest Hospital, Xi'an, China.
    This is a case report of spinal tuberculosis combined with sacroiliac joint tuberculosis, pulmonary tuberculosis, chest wall tuberculosis and tuberculous pleurisy and the image of the patient is rare, special and not typical and it looks like a halo sign. It has an important reference value for the diagnosis of spine tuberculosis although it is a rare imaging manifestation and diagnosis was confirmed by pathology after the surgery. Therefore atypical imaging is often appeared in clinical practice and it is meaningful and necessary for the diagnosis of atypical spinal tuberculosis combined with multiple organ tuberculosis. Read More

    [Pulmonary infection with Mycobacterium malmoense. Difficulties in diagnosis and treatment].
    Rev Mal Respir 2016 Sep 14. Epub 2016 Sep 14.
    Service de pneumologie et de réanimation respiratoire, CHU Sud, 80080 Amiens, France.
    Introduction: Pulmonary infection due to Mycobacterium malmoense can be difficult to diagnose. These difficulties can be responsible for a delay in the implementation of optimal treatment. Moreover, the treatment is not standardized. Read More

    [Opportunistic infections and sarcoidosis].
    Rev Med Interne 2016 Sep 14. Epub 2016 Sep 14.
    Service de médecine interne, hôpital de la Croix-Rousse, 103, grande rue de la Croix-Rousse, 69004 Lyon, France; Université Claude-Bernard-Lyon 1, 69004 Lyon, France.
    Opportunistic infections (OI) are uncommon in sarcoidosis (1 to 10%) and mostly occur in patients with previously diagnosed disease or can rarely be the presenting manifestation. The most common OIs are, in descending order: aspergillosis, cryptococcosis, and mycobacterial infections. Treatment with corticosteroids is the most frequent risk factor for OI occurrence during sarcoidosis but immunosuppressive drugs and therapy with anti-TNFα are also risk factors. Read More

    Mycobacterium smegmatis infection of a prosthetic total knee arthroplasty.
    IDCases 2016 1;5:80-2. Epub 2016 Aug 1.
    Metro Infectious Disease Consultants, McLaren Macomb Hospital, 1000 Harrington Blvd. Mount Clemens, MI 48043, United States.
    The most common organisms causing prosthetic knee joint infections are staphylococci. However, arthroplasty infections with atypical microbial pathogens, such as Mycobacteria can occur. Due to the rarity of mycobacterial prosthetic joint infections, diagnosis, treatment, and management of these atypical infections represent a clinical challenge. Read More

    [Genital tuberculosis: atypical manifestation in the pregnancy. Case report].
    Ginecol Obstet Mex 2016 May;84(5):314-8
    Background: In the last years has been an increase in cases of tu- berculosis, representing a global health problem that is also reflected in an increased of cases in pregnant population. Especially in developed countries has been observed a direct relation with VIH patients,and groups of immigrants from countries where the infection is endemic. Tuberculous disease during pregnancy presents good outcome if it is diagnosed and treated properly. Read More

    Multiple Cavitary Pulmonary Nodules Caused by Mycobacterium intracellulare.
    Korean J Fam Med 2016 Jul 21;37(4):248-52. Epub 2016 Jul 21.
    Department of Internal Medicine, Daejeon St. Mary's Hospital, The Catholic University of Korea College of Medicine, Daejeon, Korea.
    Nontuberculous mycobacteria (NTM) have been increasingly recognized as an important cause of chronic pulmonary infections. The Mycobacterium avium complex (MAC), which is composed of two species, Mycobacterium avium and Mycobacterium intracelluare, is the most commonly encountered pathogen associated with NTM lung disease. MAC pulmonary infection typically presents in a fibrocavitary form or a nodular bronchiectatic form. Read More

    Pericardial effusion with Mycobacterium avium complex in HIV-infected patients.
    BMJ Case Rep 2016 Jul 7;2016. Epub 2016 Jul 7.
    Department of General Medicine, East Lancashire Hospitals NHS Trust, Blackburn, UK.
    Disseminated atypical Mycobacterium infection is a well-known opportunistic infection in HIV-infected patients with advanced immune deficiency before the introduction of combination antiretroviral therapy. Although the disseminated infection is now rare, few cases of localised infections are reported. A 38-year-old man was diagnosed with HIV infection during asymptomatic sexual health screening. Read More

    Repeated administration of ethambutol in therapeutic dose causes testes alteration and spermatogenesis disruption in Wistar rats.
    Hum Exp Toxicol 2016 Jun 22. Epub 2016 Jun 22.
    General Toxicology Department, SI "Institute of Pharmacology & Toxicology NAMS of Ukraine," Kyiv, Ukraine.
    Ethambutol (EMB) is conventionally used to treat tuberculosis and atypical Mycobacterium infections in combination with other antimycobacterial drugs. Eventually, EMB testicular toxicity has not been explored extensively yet. The aim of the study is to evaluate testicular toxicity of EMB. Read More

    Patients with Tuberculosis Have a Dysfunctional Circulating B-Cell Compartment, Which Normalizes following Successful Treatment.
    PLoS Pathog 2016 Jun 15;12(6):e1005687. Epub 2016 Jun 15.
    Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.
    B-cells not only produce immunoglobulins and present antigens to T-cells, but also additional key roles in the immune system. Current knowledge on the role of B-cells in infections caused by intracellular bacteria is fragmentary and contradictory. We therefore analysed the phenotypical and functional properties of B-cells during infection and disease caused by Mycobacterium tuberculosis (Mtb), the bacillus causing tuberculosis (TB), and included individuals with latent TB infection (LTBI), active TB, individuals treated successfully for TB, and healthy controls. Read More

    Intracardiac tuberculomas caused by Mycobacterium tuberculosis in a dog.
    BMC Vet Res 2016 Jun 14;12(1):109. Epub 2016 Jun 14.
    Department of Small Animal Diseases with Clinic, Division of Infectious Diseases, Warsaw University of Life Sciences-SGGW, Nowoursynowska 159c Street, 02-776, Warsaw, Poland.
    Background: This paper presents an unusual form of disseminated Mycobacterium tuberculosis infection in a dog. The infection lasted at least one year and its main gross lesions were massive cardiac tuberculomas. To the best of our knowledge, this is the first report of heart tuberculomas in a dog. Read More

    Pulmonary infections in immunocompromised patients: the role of image-guided fine needle aspiration cytology.
    Cytopathology 2017 Feb 13;28(1):46-54. Epub 2016 Jun 13.
    Department of Cytology and Gynaecological Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
    Objective: To evaluate the role of fine needle aspiration cytology (FNAC) in the diagnosis of pulmonary infections in immunocompromised patients and to identify the imaging pattern of infections on computed tomography (CT).

    Materials And Methods: This was a retrospective study of 42 immunocompromised patients who underwent FNAC under image guidance owing to a clinical pulmonary infection. Each patient was evaluated for an underlying immunocompromised condition, cytological diagnosis, CT findings and complications. Read More

    Autochthonous borderline tuberculoid leprosy in a man from Florida.
    Lepr Rev 2016 Mar;87(1):101-3
    Leprosy (Hansen's disease) is a chronic contagious granulomatous disease principally affecting the skin and peripheral nervous system, caused by Mycobacterium leprae. In this report, we present a case of autochthonous leprosy in a man from Florida as the first human case reported from this region. Authors believe dermatologists need to be aware of the possibility of autochthonous transmission of leprosy in the Eastern-Southern United States, and should consider leprosy in any patient with atypical skin lesions, even when a history of contact with armadillo is missing. Read More

    Prevalence of Nontuberculous Mycobacterial Pulmonary Disease, Germany, 2009-2014.
    Emerg Infect Dis 2016 Jun;22(6):1102-5
    We analyzed routine statutory health insurance claim data to determine prevalence of nontuberculous mycobacterial pulmonary disease in Germany. Documented prevalence rates of this nonnotifiable disease increased from 2.3 to 3. Read More

    Atypical presentation of atypical mycobacteria in atypical diabetes.
    Oxf Med Case Reports 2016 Apr 27;2016(4):101-4. Epub 2016 Apr 27.
    Department of Medicine , Midnapore Medical College , Midnapore, West Bengal , India.
    A 45-year-old, non-obese male presented with low-grade, remittent fever and a fluctuant swelling over the posterior aspect of his lower left flank. Laboratory tests revealed leukocytosis, raised ESR, hyperglycemia and raised HbA1C levels. Light microscopy of Ziehl-Neelsen-stained pus sample revealed numerous acid-fast bacilli. Read More

    Decontamination of heater-cooler units associated with contamination by atypical mycobacteria.
    J Hosp Infect 2016 Jul 28;93(3):229-34. Epub 2016 Mar 28.
    University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital Birmingham, Edgbaston, Birmingham, UK.
    Background: Non-tuberculosis mycobacteria such as Mycobacterium chimaera are found widely in hospital water systems. Invasive M. chimaera infections have recently been attributed to heater-cooler units (HCUs) of cardiopulmonary bypass equipment. Read More

    Rapid-Growing Mycobacteria Infections in Medical Tourists: Our Experience and Literature Review.
    Aesthet Surg J 2016 Sep 19;36(8):NP246-53. Epub 2016 Apr 19.
    From the Departments of Medicine, Pathology, and Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
    Background: "Medical tourism" has gained popularity over the past few decades. This is particularly common with patients seeking elective cosmetic surgery in the developing world. However, the risk of severe and unusual infectious complications appears to be higher than for patients undergoing similar procedures in the United States. Read More

    Impact of Fluoroquinolone Exposure Prior to Tuberculosis Diagnosis on Clinical Outcomes in Immunocompromised Patients.
    Antimicrob Agents Chemother 2016 Jul 20;60(7):4005-12. Epub 2016 Jun 20.
    Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
    There have been concerns about an association of fluoroquinolone (FQ) use prior to tuberculosis (TB) diagnosis with adverse outcomes. However, FQ use might prevent clinical deterioration in missed TB patients, especially in those who are immunocompromised, until they receive definitive anti-TB treatment. All adult immunocompromised patients with smear-negative and culture-positive TB at a tertiary care hospital in Korea over a 2-year period were included in this study. Read More

    An Interesting Case of Non-Resolving Hepatogastric Fistula - An Unseen Cause.
    J Clin Diagn Res 2016 Feb 1;10(2):PD27-8. Epub 2016 Feb 1.
    Professor and Head, Department of Gastroenterology, T.N. Medical College & B.Y.L Nair Hospital , Mumbai, Maharashtra, India .
    Hepatic tuberculosis presents one of the rare forms of extra-pulmonary tuberculosis. It is usually secondary to infection in the lung or the gut. Tuberculous liver abscess is the rarer manifestation even in endemic areas of Mycobacterium tuberculosis. Read More

    Onchocerciasis, an undiagnosed disease in Mozambique: identifying research opportunities.
    Parasit Vectors 2016 Mar 31;9:180. Epub 2016 Mar 31.
    Department of Parasitology, Universidad de Granada, Granada, Spain.
    Background: The objective of this paper is to summarise and critically review the available data about onchocerciasis in Mozambique, in order to report epidemiological and clinical aspects related to the disease and identify gaps in knowledge. The paper is intended to raise awareness of the existence and importance of this disease and to define research priorities.

    Methods: We examined the scarce epidemiological data at our disposal: two diagnostic studies in 1997 and 1998 (first reports on the existence of onchocerciasis in Mozambique), and two Rapid Epidemiological Mapping of Onchocerciasis (REMO) surveys in 2001 and 2007. Read More

    Pediatric Atypical Mycobacterium Infection Presenting as Wheezing and Concern for Foreign Body Aspiration.
    Cureus 2016 Feb 12;8(2):e491. Epub 2016 Feb 12.
    Department of Pediatric Otolaryngology, Children's Hospital of UPMC.
    Atypical mycobacterium infection most commonly presents as asymptomatic cervical lymphadenitis in immunocompetent children. Over the last several decades, rates of Mycobacterium avium complex (MAC) infection have been increasing in both number and severity, with more cases of pulmonary infection reported in healthy children. However, guidelines on how to treat children with these infections remain unclear. Read More

    Primary Neuritic Hansen's Disease presenting as Ulnar Nerve Abscess in a Human Immunodeficiency Virus Positive Patient.
    Indian J Lepr 2015 Jul-Sep;87(3):169-74
    Leprosy has been increasingly known to have an enigmatic relationship with human immunodeficiency virus infection. Co-infection may result in atypical manifestations of leprosy. A 45-year old human immunodeficiency virus-positive male; agricultural laborer presented with a swelling over right elbow, right hand deformity, generalized itching and recurrent vesicles overthe perinasal area. Read More

    Disseminated Mycobacterium marinum Infection With a Destructive Nasal Lesion Mimicking Extranodal NK/T Cell Lymphoma: A Case Report.
    Medicine (Baltimore) 2016 Mar;95(11):e3131
    From the Divisions of Pulmonary Medicine (TA, MI, HN, ST, TB) and Hematology (TK, TS, SO), Department of Medicine; Division of Diagnostic Pathology (KK); and Center for Infectious Diseases and Infection Control (KS, NH), Keio University School of Medicine; Department of Mycobacteriology, Leprosy Research Center, National Institute of Infectious Diseases (NN, YH), Tokyo, Japan.
    Mycobacterium marinum is a ubiquitous waterborne organism that mainly causes skin infection in immunocompetent patients, and its disseminated infection is rare. Extranodal NK/T cell lymphoma, nasal type (ENKL) usually localizes at the nasal and/or paranasal area, but occasionally disseminates into the skin/soft tissue and gastrointestinal tract. Compromised immunity is a risk factor for developing nontuberculous mycobacterial (NTM) infection and malignant lymphoma, and the 2 diseases may share similar clinical presentation; however, only a few reports have described NTM infection mimicking malignant lymphoma. Read More

    Non tuberculous mycobacterial lesion of the parotid gland and facial skin in a 4year old girl: A proposed treatment strategy.
    Am J Otolaryngol 2016 Mar-Apr;37(2):89-94. Epub 2015 Sep 10.
    Department of Otolaryngology/Head & Neck Surgery, Section of Pediatric Otolaryngology.
    Objective: We report a case of a parotid-facial caseating granulomatous infection caused by atypical mycobacteria (Mycobacterium avium) in an immuno-competent child. The size and depth of the lesion and its proximity to the facial nerve present a challenge for a purely surgical treatment strategy. An alternative treatment strategy is developed to avoid severe disfigurement. Read More

    Clinically unrecognized miliary tuberculosis: an autopsy study.
    Ann Saudi Med 2016 Jan-Feb;36(1):42-50
    Ivana Savic, Faculty of Medicine,, University of Belgrade,, Institute of Pathology, Dr Subotica 1 Belgrade 11000 Serbia, . T: +381 11 3643 409,
    Background: Miliary tuberculosis (TB) usually presents with atypical clinical manifestations; thus it is often recognized only at autopsy.

    Objectives: Our objectives were to study the frequency of MT diagnosed at autopsy and determine clinical diagnoses that masked TB, as well as causes of death and comorbidities.

    Design: Retrospective study of all autopsies performed between 2008 and 2014. Read More

    Pacemaker pocket infection due to environmental mycobacteria: Successful management of an outbreak and steps for prevention in future.
    Indian Heart J 2016 Jan-Feb;68(1):63-7. Epub 2016 Jan 14.
    Senior Surgeon, Tata Main Hospital, Jamshedpur, India.
    Background: An outbreak of surgical site infection (SSI) due to environmental mycobacteria (EMB) occurred in a hospital in Eastern India.

    Method: A quality improvement project (QIP) was undertaken to analyze the causes and prevent further outbreak. Step (1) Proof of the need: Four patients who had undergone pacemaker implantation consecutively during a 10-day period developed SSI. Read More

    Genome-wide mosaicism within Mycobacterium abscessus: evolutionary and epidemiological implications.
    BMC Genomics 2016 Feb 17;17:118. Epub 2016 Feb 17.
    Laboratoire de Biologie intégrative des populations, Evolution moléculaire, Ecole Pratique des Hautes Etudes, Paris, France.
    Background: In mycobacteria, conjugation differs from the canonical Hfr model, but is still poorly understood. Here, we quantified this evolutionary processe in a natural mycobacterial population, taking advantage of a large clinical strain collection of the emerging pathogen Mycobacterium abscessus (MAB).

    Results: Multilocus sequence typing confirmed the existence of three M. Read More

    High incidence of tuberculosis in patients treated for hepatitis C chronic infection.
    Braz J Infect Dis 2016 Mar-Apr;20(2):205-9. Epub 2016 Feb 9.
    Gastroenterology Division, Universidade Federal de São Paulo (UNIFESP), Sao Paulo, SP, Brazil.
    Brazil is one of the 22 countries that concentrates 80% of global tuberculosis cases concomitantly to a large number of hepatitis C carriers and some epidemiological risk scenarios are coincident for both diseases. We analyzed tuberculosis cases that occurred during α-interferon-based therapy for hepatitis C in reference centers in Brazil between 2001 and 2012 and reviewed their medical records. Eighteen tuberculosis cases were observed in patients submitted to hepatitis C α-interferon-based therapy. Read More

    Isolated anterior mediastinal tuberculosis in an immunocompetent patient.
    BMC Pulm Med 2016 Feb 3;16:24. Epub 2016 Feb 3.
    Department of Gastroenterology, Connolly Hospital, Blanchardstown, Dublin, Dublin 15, Ireland.
    Background: The differential diagnosis of a mediastinal mass is a common challenge in clinical practice, with a wide range of differential diagnosis to be considered. One of the rarer causes is tuberculosis. Atypical presentations of tuberculosis are well documented in immunocompromised patients, but should also be considered in the immunocompetent. Read More

    Multifocal musculoskeletal tuberculosis mimicking multiple bone metastases: a case report.
    BMC Infect Dis 2016 Jan 29;16:34. Epub 2016 Jan 29.
    Fifth Affiliated Hospital of Wenzhou Medical University, Lishui, China.
    Background: The occurrence of non-contiguous, multiple, and remote involvement tuberculous spondylitis is rare. The clinical presentation in patients with multifocal musculoskeletal tuberculosis may closely mimic that in patients with multiple bone metastases, which makes the accurate clinical diagnosis challenging. Herein, we report a multifocal musculoskeletal tuberculosis case that was misdiagnosed for 8 months as multiple bone metastases. Read More

    Mycobacterium avium complex olecranon bursitis resolves without antimicrobials or surgical intervention: A case report and review of the literature.
    IDCases 2015 13;2(2):59-62. Epub 2015 Apr 13.
    Division of Infectious Diseases, University of Utah School of Medicine, 30 N 1900 E, Room 4B319, Salt Lake City, UT 84132, United States.
    Introduction: Nontuberculous mycobacteria are an uncommon cause of septic olecranon bursitis, though cases have increasingly been described in both immunocompromised and immunocompetent hosts. Guidelines recommend a combination of surgical resection and antimicrobials for treatment. This case is the first reported case of nontuberculous mycobacterial olecranon bursitis that resolved without medical or surgical intervention. Read More

    Under the Sea: Superficial Skin Infection With an Atypical Cause.
    Pediatr Emerg Care 2016 Jan 16. Epub 2016 Jan 16.
    From the Department of Pediatrics, *Inova Children's Hospital, Falls Church; and †Virginia Commonwealth University School of Medicine, Inova Campus, Fairfax, VA.
    Traumatic abrasions on human extremities as a result of direct contact with sea, lake, river, or aquarium animals or from traumatic injuries sustained in seawater may develop into solitary or linear granulomatous lesions. One of the more common microbial etiologies for such infections is Mycobacterium marinum. An astute pediatrician, family physician, or nurse practitioner should have a high index of suspicion and obtain specific cultures to support the growth of Mycobacterium species. Read More

    Leprous neuromyositis: A rare clinical entity and review of the literature.
    Indian J Med Microbiol 2016 Jan-Mar;34(1):95-7
    Department of Medicine, Christian Medical College, Vellore, Tamil Nadu, India.
    Mycobacterium leprae, the causative agent of leprosy (Hansen's disease), is a slow growing intracellular acid-fast bacillus that affects the skin, peripheral nerves and respiratory tract. In patients with suppressed cell-mediated immunity, the infiltration of the Bacilli can produce disseminated illness such as leprous neuromyositis. We reported a case of 56-year-old gentleman presenting with pyrexia of unknown origin, asymmetric sensory motor axonal polyneuropathy and was on chronic exogenous steroid therapy. Read More

    [Osteo-cutaneous Mycobacterium marinum infection of the elbow and reconstruction with radial collateral artery perforator-based propeller flap].
    Ann Chir Plast Esthet 2016 Aug 31;61(4):311-5. Epub 2015 Dec 31.
    Service de chirurgie plastique, reconstructrice et esthétique, centre SOS main, CHU Ch.-Nicolle, 76031 Rouen, France.
    Mycobacterium marinum is an atypical and non-tuberculosis mycobacterium that mainly leads to cutaneous infections. Infections occur through inoculation of the organism through injury to the skin in the presence of contaminated water or fish. The patient often presents with unspecific symptoms and the evolution, in the absence of adequate treatment, is characterized by an expansion of the cutaneous lesion and a spread to deep structures. Read More

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