37,115 results match your criteria Attention Deficit Hyperactivity Disorder


Neonatal jaundice, attention deficit hyperactivity disorder and familial effects. A Swedish register study with sibling analysis.

Acta Paediatr 2020 Jul 10. Epub 2020 Jul 10.

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.

Aim: Neonatal jaundice is associated with higher risk of attention deficit hyperactivity disorder (ADHD), but it is unclear if the association is influenced by genetic and other familial factors. In this large population-based study, we investigated the association between neonatal jaundice and ADHD while adjusting for familial factors.

Methods: We linked several Swedish registers to identify all singleton births without congenital malformations between 1992 and 2000 (n=814,420, including 384,290 full siblings) and followed them up until 2009. Read More

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http://dx.doi.org/10.1111/apa.15475DOI Listing

Behavioral tests assessing neuropsychiatric phenotypes in adolescent mice reveal strain- and sex-specific effects.

Sci Rep 2020 Jul 9;10(1):11263. Epub 2020 Jul 9.

Interdisciplinary Neurobehavioral Core, Heidelberg University, Heidelberg, Germany.

In humans, infancy and adolescence are associated with major changes in synaptic functions and ongoing maturation of neural networks, which underlie the major behavioral changes during these periods. Among adult cases with neuropsychiatric disorders including autism spectrum disorder, schizophrenia, attention deficit hyperactivity, and bipolar disorders, 50% have developed behavioral symptoms and received a diagnosis before 15 years of age. However, most of the behavioral studies in mice modeling neuropsychiatric phenotypes are performed in adult animals, missing valuable phenotypic information related to the effect of synaptic maturation during development. Read More

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http://dx.doi.org/10.1038/s41598-020-67758-0DOI Listing

Cross-Disorder Analysis of Brain Structural Abnormalities in Six Major Psychiatric Disorders: A Secondary Analysis of Mega- and Meta-analytical Findings From the ENIGMA Consortium.

Biol Psychiatry 2020 May 11. Epub 2020 May 11.

Department of Psychiatry, University of Münster, Münster, Germany.

Background: Neuroimaging studies have consistently reported similar brain structural abnormalities across different psychiatric disorders. Yet, the extent and regional distribution of shared morphometric abnormalities between disorders remains unknown.

Methods: Here, we conducted a cross-disorder analysis of brain structural abnormalities in 6 psychiatric disorders based on effect size estimates for cortical thickness and subcortical volume differences between healthy control subjects and psychiatric patients from 11 mega- and meta-analyses from the ENIGMA (Enhancing Neuro Imaging Genetics Through Meta Analysis) consortium. Read More

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http://dx.doi.org/10.1016/j.biopsych.2020.04.027DOI Listing

Epigenetic Basis of Lead-Induced Neurological Disorders.

Int J Environ Res Public Health 2020 Jul 7;17(13). Epub 2020 Jul 7.

School of Food and Bioengineering, Hefei University of Technology, Hefei 230009, China.

Environmental lead (Pb) exposure is closely associated with pathogenesis of a range of neurological disorders, including Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), attention deficit/hyperactivity disorder (ADHD), etc. Epigenetic machinery modulates neural development and activities, while faulty epigenetic regulation contributes to the diverse forms of CNS (central nervous system) abnormalities and diseases. As a potent epigenetic modifier, lead is thought to cause neurological disorders through modulating epigenetic mechanisms. Read More

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http://dx.doi.org/10.3390/ijerph17134878DOI Listing

Effects of Extended-Release Methylphenidate Treatment on Cognitive Task Performance in Children with Autism Spectrum Disorder and Attention-Deficit/Hyperactivity Disorder.

J Child Adolesc Psychopharmacol 2020 Jul 9. Epub 2020 Jul 9.

Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA.

To examine the effectiveness of four doses of psychostimulant medication, combining extended-release methylphenidate (ER-MPH) in the morning with immediate-release MPH (IR-MPH) in the afternoon, on cognitive task performance. The sample comprised 24 children (19 boys and 5 girls) who met the (DSM-IV-TR) criteria for an autism spectrum disorder (ASD) on the and the , and had significant symptoms of attention-deficit/hyperactivity disorder (ADHD). This sample consisted of elementary school-age, community-based children (mean chronological age = 8. Read More

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http://dx.doi.org/10.1089/cap.2020.0004DOI Listing

Symptoms of Internet Gaming Disorder, Inattention, and Impulsivity: a Cross-Sectional Study Conducted in the United Arab Emirates.

Authors:
Zahir Vally

Psychiatr Q 2020 Jul 8. Epub 2020 Jul 8.

Department of Cognitive Sciences, United Arab Emirates University, P. O. Box 1551, Al Ain, UAE.

The addictive use of internet video games is now recognized as a valid diagnostic construct by both the World Health Organization and the American Psychiatric Association. A burgeoning body of preliminary evidence points to a relationship between attention deficit and hyperactivity disorder (ADHD) symptoms as being a risk factor for behaviors indicative of internet gaming disorder (IGD), however, studies have rarely examined ADHD's two diagnostic constructs, inattention and impulsivity, separately. Moreover, IGD research is non-existent in Middle Eastern contexts. Read More

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http://dx.doi.org/10.1007/s11126-020-09799-2DOI Listing

Knowledge, attitude, and behavior of elementary teachers regarding attention deficit hyperactivity disorder.

J Educ Health Promot 2020 28;9:120. Epub 2020 May 28.

Department of Biostatistics and Epidemiology, Isfahan University of Medical Sciences, Isfahan, Iran.

Introduction: Attention deficit hyperactivity disorder (ADHD) is a common disorder in child psychiatry, which has a greater impact on the future life of the children affected in case of being untreated and undiagnosed. Given the undeniable role of teachers in improving this disorder and preventing its destructive consequences on children, the present research has examined the knowledge, attitude, and practice of elementary school teachers regarding ADHD.

Materials And Methods: This was a descriptive, cross-sectional study carried out in 2019. Read More

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http://dx.doi.org/10.4103/jehp.jehp_696_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325758PMC

Attention-Deficit/Hyperactivity Disorder Patients May Have Undiagnosed Narcolepsy.

Cureus 2020 Jun 4;12(6):e8436. Epub 2020 Jun 4.

Helsinki Sleep Clinic, Vitalmed Research Center, Helsinki, FIN.

Background Attention-deficit/hyperactivity disorder (ADHD) patients have many comorbidities. Narcoleptic patients have a big prevalence of ADHD (15%-30%). Both groups suffer from similar symptoms and benefit from the same class of medications. Read More

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http://dx.doi.org/10.7759/cureus.8436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336577PMC

A Review of the Current Treatment of Tourette Syndrome.

J Pediatr Pharmacol Ther 2020 ;25(5):401-412

Tourette syndrome is a hyperkinetic movement disorder that presents before age 18 years and involves motor and phonic tics that may present with a wide range of severity. The severity and presentation of tics in an individual may fluctuate over time. Tourette syndrome may affect social relationships and school attendance, and may result in depression. Read More

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http://dx.doi.org/10.5863/1551-6776-25.5.401DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337131PMC
January 2020

The ADHD teen integrative data analysis longitudinal (TIDAL) dataset: background, methodology, and aims.

BMC Psychiatry 2020 Jul 8;20(1):359. Epub 2020 Jul 8.

Department of Psychology, Florida International University, 11200 SW 8th Street, Miami, FL, 33199, USA.

Background: The Attention Deficit Hyperactivity Disorder (ADHD) Teen Integrative Data Analysis Longitudinal (TIDAL) dataset integrates data from four randomized trials.

Method: Participants with ADHD (N = 854; 72.5% male, 92. Read More

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http://dx.doi.org/10.1186/s12888-020-02734-6DOI Listing

Migraine, attention deficit hyperactivity disorder and screen time in children attending a Sri Lankan tertiary care facility: are they associated?

BMC Neurol 2020 Jul 8;20(1):275. Epub 2020 Jul 8.

Department of Community Medicine, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.

Background: Headache and Attention Deficit Hyperactivity Disorder (ADHD) are two relatively common, neuropsychiatric conditions seen in children. Recent studies have shown an association between these two disorders, which are otherwise distinct conditions. This study aims to assess the association between migraine and ADHD, as well as the association between screen-time and these two conditions, among children attending a Sri Lankan tertiary care facility. Read More

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http://dx.doi.org/10.1186/s12883-020-01855-5DOI Listing

Zonulin-Dependent Intestinal Permeability in Children Diagnosed with Mental Disorders: A Systematic Review and Meta-Analysis.

Nutrients 2020 Jul 3;12(7). Epub 2020 Jul 3.

Unit for Nutrition Research, Faculty of Food and Nutritional Sciences, University of Iceland, 101 Reykjavik, Iceland.

Worldwide, up to 20% of children and adolescents experience mental disorders, which are the leading cause of disability in young people. Research shows that serum zonulin levels are associated with increased intestinal permeability (IP), affecting neural, hormonal, and immunological pathways. This systematic review and meta-analysis aimed to summarize evidence from observational studies on IP in children diagnosed with mental disorders. Read More

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http://dx.doi.org/10.3390/nu12071982DOI Listing

International Consensus Statement for the Screening, Diagnosis, and Treatment of Adolescents with Concurrent Attention-Deficit/Hyperactivity Disorder and Substance Use Disorder.

Eur Addict Res 2020 07 7:1-10. Epub 2020 Jul 7.

Parnassia Addiction Research Centre (PARC), Parnassia Psychiatric Institute, The Hague, The Netherlands.

Background: Childhood attention-deficit/hyperactivity disorder (ADHD) is a risk factor for substance misuse and substance use disorder (SUD) in adolescence and (early) adulthood. ADHD and SUD also frequently co-occur in treatment-seeking adolescents, which complicates diagnosis and treatment and is associated with poor treatment outcomes. Research on the effect of treatment of childhood ADHD on the prevention of adolescent SUD is inconclusive, and studies on the diagnosis and treatment of adolescents with ADHD and SUD are scarce. Read More

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http://dx.doi.org/10.1159/000508385DOI Listing

Gut instincts: vitamin D/vitamin D receptor and microbiome in neurodevelopment disorders.

Open Biol 2020 07 8;10(7):200063. Epub 2020 Jul 8.

Division of Gastroenterology and Hepatology, Medicine, University of Illinois at Chicago, Chicago 60612, IL, USA.

The gut microbiome regulates a relationship with the brain known as the gut-microbiota-brain (GMB) axis. This interaction is influenced by immune cells, microbial metabolites and neurotransmitters. Recent findings show gut dysbiosis is prevalent in autism spectrum disorder (ASD) as well as attention deficit hyperactivity disorder (ADHD). Read More

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http://dx.doi.org/10.1098/rsob.200063DOI Listing

Low self-control and aggression exert serial mediation between inattention/hyperactivity problems and severity of internet gaming disorder features longitudinally among adolescents.

J Behav Addict 2020 Jul 2. Epub 2020 Jul 2.

1Department of Preventive Medicine, College of Medicine, Catholic University of Korea, Seoul, Korea.

Objectives: We examined serial mediating roles of low self-control and aggression in explaining relationships between levels of inattention and hyperactivity problems (IHPs) and severity of Internet gaming disorder (IGD) features when exposed to online games among adolescents without Attention deficit hyperactivity disorder (ADHD) stratified by gender using three-wave longitudinal study.

Method: The sample comprised a total of 1,732 family dyads from a study that was conducted among seventh graders without diagnoses of ADHD at baseline. Levels of IHPs were assessed by the parent reported Korean version of the ADHD rating scale at baseline (wave1). Read More

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http://dx.doi.org/10.1556/2006.2020.00039DOI Listing

A Gain-of-Function Mutation in KCNMA1 Causes Dystonia Spells Controlled With Stimulant Therapy.

Mov Disord 2020 Jul 7. Epub 2020 Jul 7.

Department of Pediatrics, Duke University Medical Center, Durham, North Carolina, USA.

Background: The mutations of KCNMA1 BK-type K channel have been identified in patients with various movement disorders. The underlying pathophysiology and corresponding therapeutics are lacking.

Objectives: To report our clinical and biophysical characterizations of a novel de novo KCNMA1 variant, as well as an effective therapy for the patient's dystonia-atonia spells. Read More

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http://dx.doi.org/10.1002/mds.28138DOI Listing

Primary headache in childhood associated with psychiatric disturbances: an update.

Eur Rev Med Pharmacol Sci 2020 Jun;24(12):6893-6898

Department Clinical and Experimental Medicine, Child and Adolescent Neuropsychiatry, University of Catania, Catania, Italy.

Objective: Primary headache disorders in children are one of the most prominent topics in the pediatric neurology literature. However, there are many unsolved aspects, including the conditions associated with migraine. The present study aims to report on the frequency of behavioral comorbidities in the setting of primary headache in childhood. Read More

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http://dx.doi.org/10.26355/eurrev_202006_21680DOI Listing

[Update on attention deficit hyperactivity disorder].

Nervenarzt 2020 Jul;91(7):573-574

Schön Klinik Roseneck, Prien am Chiemsee, Deutschland.

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http://dx.doi.org/10.1007/s00115-020-00926-9DOI Listing

A Latent Class Analysis of Perceived Neighborhood Conditions Associated with Mental Disorders Among Children in the United States.

Child Psychiatry Hum Dev 2020 Jul 6. Epub 2020 Jul 6.

Department of Epidemiology and Biostatistics, College for Public Health and Social Justice, Saint Louis University, Salus Center Suite 300, 3545 Lafayette Ave., Saint Louis, MO, 63104, USA.

The current study examined the association between perceived neighborhood conditions and common childhood mental disorders in a nationally representative sample of children in the U.S. The data were derived from the 2017 National Survey of Children's Health, including American children aged 6-17 years (N = 15,438). Read More

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http://dx.doi.org/10.1007/s10578-020-01020-6DOI Listing

Age-Related Changes in Auditory Nogo-N200 Latency in Medication-Naïve Children and Adolescents with Attention-Deficit/Hyperactivity Disorder.

Psychiatry Investig 2020 Jul 8. Epub 2020 Jul 8.

Department of Psychiatry, Seoul Hospital, College of Medicine, Soonchunhyang University, Seoul, Republic of Korea.

Objective: Event-related potential (ERP) changes with brain development in healthy children and adolescents. However, few studies have focused on age-related changes in the N200 and P300 components among individuals with attention-deficit/hyperactivity disorder (ADHD). Therefore, this study aimed to assess age-related differences in the auditory nogo-N200 components in individuals with ADHD. Read More

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http://dx.doi.org/10.30773/pi.2020.0083DOI Listing

Methylphenidate has mild hyperglycemic and hypokalemia effects and increases leukocyte and neutrophil counts.

Medicine (Baltimore) 2020 Jul;99(27):e20931

Department of Internal Medicine C, Tel Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel.

Various psychotropic drugs may affect the hematological and biochemical profiles of plasma and its metabolism. Carbamazepine, the most well-known psychotropic drug, can cause substantial hyponatremia. Methylphenidate, a piperidine derivative structurally related to amphetamines, acts as a central nervous system stimulant. Read More

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http://dx.doi.org/10.1097/MD.0000000000020931DOI Listing

Health-Related Quality of Life in Biliary Atresia Patients with Native Liver or Transplantation.

Eur J Pediatr Surg 2020 Jul 6. Epub 2020 Jul 6.

Department of Pediatric Surgery, University Medical Center Groningen, Groningen, The Netherlands.

Introduction:  We aimed to assess health-related quality of life (HrQoL) in biliary atresia (BA) patients, based on original data and a literature review, and to determine factors associated with their HrQoL.

Materials And Methods:  We reviewed available studies describing HrQoL in BA patients. We assessed HrQoL in Dutch BA patients (6-16 years) using the validated Child Health Questionnaire. Read More

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http://dx.doi.org/10.1055/s-0040-1712932DOI Listing

Pilot data and case example of the initial visit in a multidisciplinary transition-age program (TAP).

Epilepsy Behav 2020 Jul 3;111:107242. Epub 2020 Jul 3.

Minnesota Epilepsy Group, P.A., 225 Smith Avenue North, Suite 201, St. Paul, MN 55102, United States.

The process of transition from pediatric to adult epilepsy care has received increased attention and emphasis in recent literature, particularly related to the assertion that effective transition is likely to lead to improved medical and psychosocial outcomes. However, the majority of current transition literature focuses on the structure of a transition program, with very little research providing relevant clinical data during the transition period and beyond. The current paper attempts to address this gap in the literature by providing pilot data on participants who engaged in the initial visit of a multidisciplinary transition-focused program housed in a level 4 epilepsy center in the Midwest. Read More

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http://dx.doi.org/10.1016/j.yebeh.2020.107242DOI Listing

Links between Child and Adolescent Psychiatric Disorders and Cardiovascular Risk.

Can J Cardiol 2020 Jul 3. Epub 2020 Jul 3.

Department of Psychiatry, Hospital for Sick Children Department of Psychiatry, Faculty of Medicine, University of Toronto.

This narrative review, emphasizing children and adolescents, addresses the link between five psychiatric disorders and cardiovascular risk: attention deficit hyperactivity disorder (ADHD), autism spectrum disorders, anxiety disorders, depression, and bipolar disorders. The evidence regarding cardiovascular risk factors, non-invasive measures of early atherosclerosis, and cardiovascular disease prevalence and/or mortality is summarized. Whereas multiple studies have examined stimulant treatment of ADHD in relation to cardiovascular death, and autonomic-vagal function in autism spectrum disorders, little is known regarding atherosclerotic cardiovascular disease in these conditions. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.06.023DOI Listing

SLC2A3 rs12842 polymorphism and risk for Alzheimer's disease.

Neurol Res 2020 Jul 4:1-9. Epub 2020 Jul 4.

Department of Neurology, Laboratory of Neurogenetics, University of Thessaly, University Hospital of Larissa , Larissa, Greece.

Background: Many studies support the hypothesis that brain glucose dysregulation contributes to neurodegeneration and disease progression. The SLC2A3 gene encodes the Neuronal Glucose Transporter 3 (GLUT3), a critical molecule for glucose transport into the neuron. The GLUT3 rs12842 polymorphism has been associated with an increased risk for attention-deficit/hyperactivity disorder (ADHD). Read More

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http://dx.doi.org/10.1080/01616412.2020.1786973DOI Listing

Epigenetics and Attention-Deficit/Hyperactivity Disorder: New Perspectives?

Front Psychiatry 2020 17;11:579. Epub 2020 Jun 17.

Department of Child and Adolescent Psychiatry, AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.

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http://dx.doi.org/10.3389/fpsyt.2020.00579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311572PMC

Lateral Prefrontal Theta Oscillations Reflect Proactive Cognitive Control Impairment in Males With Attention Deficit Hyperactivity Disorder.

Front Syst Neurosci 2020 18;14:37. Epub 2020 Jun 18.

Laboratorio de Neurociencia Social y Neuromodulación, Centro de Investigación en Complejidad Social (neuroCICS), Universidad del Desarrollo, Santiago, Chile.

Attention Deficit Hyperactivity Disorder (ADHD) is a common neuropsychiatric disorder in which children present prefrontal cortex (PFC) related functions deficit. Proactive cognitive control is a process that anticipates the requirement of cognitive control and crucially depends on the maturity of the PFC. Since this process is important to ADHD symptomatology, we here test the hypothesis that children with ADHD have proactive cognitive control impairments and that these impairments are reflected in the PFC oscillatory activity. Read More

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http://dx.doi.org/10.3389/fnsys.2020.00037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314966PMC

The co-occurrence between symptoms of internet gaming disorder and psychiatric disorders in childhood and adolescence: prospective relations or common causes?

J Child Psychol Psychiatry 2020 Jul 5. Epub 2020 Jul 5.

Department of Psychology, Norwegian University of Science and Technology, Trondheim, Norway.

Background: Internet gaming disorder (IGD) is highlighted as a condition for further study in the Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM-5). Some studies indicate that IGD appears comorbid with other psychiatric disorders. We examine concurrent and prospective links between symptoms of IGD and symptoms of common psychiatric disorders in childhood and adolescence to determine whether observed comorbidity is a result of (a) reciprocal relations or (b) common underlying causes. Read More

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http://dx.doi.org/10.1111/jcpp.13289DOI Listing

Bi-allelic Mutations in ALDH5A1 is associated with succinic semialdehyde dehydrogenase deficiency and severe intellectual disability.

Gene 2020 Jul 1:144918. Epub 2020 Jul 1.

Genetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran. Electronic address:

Homozygous mutations of ALDH5A1 have been reportedly associated with Succinic semialdehyde dehydrogenase deficiency (SSADHD) that affects gamma-aminobutyric acid (GABA) catabolism and evinces a wide range of clinical phenotype from mild intellectual disability to severe neurodegenerative disorders. We report clinical and molecular data of a Lor family with 2 affected members presenting with severe intellectual disability, developmental delay, and generalized tonic-clonic seizures. A comprehensive genetic study that included whole-exome sequencing identified a homozygous missense substitution (NM_001080:c. Read More

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http://dx.doi.org/10.1016/j.gene.2020.144918DOI Listing

Hyperactive ACC-MDT Pathway Suppresses Prepulse Inhibition in Mice.

Schizophr Bull 2020 Jul 4. Epub 2020 Jul 4.

Center for Synaptic Brain Dysfunction, Institute for Basic Science, Daejeon, South Korea.

Altered prepulse inhibition (PPI) is an endophenotype associated with multiple brain disorders, including schizophrenia. Circuit mechanisms that regulate PPI have been suggested, but none has been demonstrated through direct manipulations. IRSp53 is an abundant excitatory postsynaptic scaffold implicated in schizophrenia, autism spectrum disorders, and attention-deficit/hyperactivity disorder. Read More

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http://dx.doi.org/10.1093/schbul/sbaa090DOI Listing

Cannabis use disorder trajectories and their prospective predictors in a large population-based sample of young Swiss men.

Addiction 2020 Jul 4. Epub 2020 Jul 4.

Addiction Medicine, Lausanne University Hospital and University of Lausanne, Rue du Bugnon 23, CH-1011, Lausanne, Switzerland.

Background And Aims: Cannabis use disorder (CUD) is frequent in adolescence and often goes into remission towards adulthood. This study aimed to estimate trajectories of CUD severity (CUDS) in Swiss men from 20 to 25 years old and to identify prospective predictors of these trajectories.

Design: Latent class growth analysis of self-reported CUDS in a cohort study with three data collection waves. Read More

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http://dx.doi.org/10.1111/add.15177DOI Listing

Caffeine Consumption plus Physical Exercise Improves Behavioral Impairments and Stimulates Neuroplasticity in Spontaneously Hypertensive Rats (SHR): an Animal Model of Attention Deficit Hyperactivity Disorder.

Mol Neurobiol 2020 Jul 3. Epub 2020 Jul 3.

Graduate Program of Neuroscience, Centre of Biological Sciences, Federal University of Santa Catarina, Florianópolis, SC, 88049-900, Brazil.

Attention deficit hyperactivity disorder (ADHD) is a prevalent and disabling disorder, mainly characterized by hyperactivity, inattention, and impulsivity, but also by olfactory and memory impairments that frequently persist throughout lifetime. The pathophysiology of ADHD is complex, involving several brain regions and neural pathways including alterations in adenosine neuromodulation. The administration of caffeine (a non-selective adenosine receptor antagonist) and physical exercise have been independently pointed as effective approaches for the management of ADHD symptoms. Read More

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http://dx.doi.org/10.1007/s12035-020-02002-4DOI Listing

Movement disorders and use of risperidone and methylphenidate: a review of case reports and an analysis of the WHO database in pharmacovigilance.

Eur Child Adolesc Psychiatry 2020 Jul 3. Epub 2020 Jul 3.

Pharmacoepidemiology, Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zurich, Vladimir-Prelog-Weg 4, 8093, Zurich, Switzerland.

For patients with attention deficit hyperactivity disorder and comorbid conduct-dissocial disorder, a combination therapy of the psychostimulant methylphenidate and the antipsychotic risperidone may be prescribed. Case reports describe the occurrence of movement disorders under this combination therapy, but clinical trials had limited power to detect these events. This study aimed (1) to summarise published case reports and (2) to analyse pharmacovigilance data consisting of adverse drug event reports to elucidate these reactions. Read More

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http://dx.doi.org/10.1007/s00787-020-01589-2DOI Listing
July 2020
3.554 Impact Factor

Efficacy of psychosocial interventions for children with ADHD and emotion dysregulation: a systematic review.

Psychiatry Res 2020 May 30;291:113151. Epub 2020 May 30.

Centre Hospitalo-Universitaire de Montpellier, Service Médecine Psychologique de l'Enfant et de l'Adolescent, Montpellier, Hérault, France; INSERM U1018 CESP/Psychiatry, development and trajectories, Montpellier.

Attention-Deficit Hyperactivity Disorder (ADHD) is frequently associated with emotion dysregulation (ED) that is characterized by excessive and inappropriate emotional reactions. Children with ADHD and ED present significant social, academic and family functioning impairments. These findings indicate that ED should be regularly monitored in children with ADHD and should be managed with targeted therapeutic interventions. Read More

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http://dx.doi.org/10.1016/j.psychres.2020.113151DOI Listing

Network Structure of Physical, Cognitive, and Emotional Symptoms at Preseason Baseline in Student Athletes with Attention-Deficit/ Hyperactivity Disorder.

Arch Clin Neuropsychol 2020 Jun 3. Epub 2020 Jun 3.

Department of Psychology, Harvard University, Cambridge, MA, USA.

Objective: Preexisting attention-deficit/hyperactivity disorder (ADHD) may be a risk factor for worse outcome following sport-related concussion. We used a statistical and psychometric approach known as network analysis to examine the architecture of physical, cognitive, and emotional symptoms at preseason baseline among student athletes with ADHD.

Method: A cohort of 44,527 adolescent student athletes completed baseline preseason testing with ImPACT® between 2009 and 2015. Read More

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http://dx.doi.org/10.1093/arclin/acaa030DOI Listing

An executive functioning perspective in neurofibromatosis type 1: from ADHD and autism spectrum disorder to research domains.

Childs Nerv Syst 2020 Jul 3. Epub 2020 Jul 3.

Office of the Clinical Director and Medical Genetic Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.

Purpose: Neurofibromatosis type 1 (NF1) is a rare monogenic disorder associated with executive function (EF) deficits and heightened risk for attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). The goal of this paper is to understand how EFs provide a common foundation to understand vulnerabilities for ADHD and ASD within NF1.

Methods: A literature review and synthesis was conducted. Read More

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http://dx.doi.org/10.1007/s00381-020-04745-wDOI Listing

Perspective on Melatonin Use for Sleep Problems in Autism and Attention-Deficit Hyperactivity Disorder: A Systematic Review of Randomized Clinical Trials.

Cureus 2020 May 28;12(5):e8335. Epub 2020 May 28.

Psychiatry, Griffin Memorial Hospital, Norman, USA.

Melatonin is a hormone produced by the pineal gland and is available over the counter for treating sleep problems in the pediatric population. We conducted a systematic review of randomized clinical trials (RCTs) on MEDLINE and included six studies that met our inclusion criteria. RCTs were conducted in patients from two to 18 years of age with a diagnostic and statistical manual of mental disorders (DSM)-IV diagnosis of autism spectrum disease (ASD) and/or attention-deficit hyperactivity disorder (ADHD) in both short-term and long-term RCTs ranging from eight-week to 52-week studies. Read More

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http://dx.doi.org/10.7759/cureus.8335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325410PMC

Adult attention deficit hyperactivity disorder clinic: An interprofessional collaboration.

J Am Pharm Assoc (2003) 2020 Jun 29. Epub 2020 Jun 29.

Objective: To review the experience of a pharmacist-led interprofessional attention deficit hyperactivity disorder (ADHD) clinic in a large integrated health care system.

Practice Description: Kaiser Permanente Northwest (KPNW) is a nonprofit managed health care system that provides integrated care to more than 625,000 members in Oregon and southwest Washington. Most health care encounters occur within KPNW facilities and with KPNW health professionals or support staff using a common electronic medical record. Read More

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http://dx.doi.org/10.1016/j.japh.2020.03.020DOI Listing

Physical Fitness and Dynamic Balance in Medication Naïve Turkish Children with ADHD.

Percept Mot Skills 2020 Jul 2:31512520938517. Epub 2020 Jul 2.

Department of Child and Adolescent Psychiatry, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.

This study investigated physical fitness levels and dynamic balance in medication-naïve children with Attention-Deficit/Hyperactivity Disorder (ADHD). Participants were 24 medication-naïve Turkish children with ADHD (4 girls, 20 boys) and 19 typically developing (TD) Turkish children (4 girls, 15 boys). We measured physical fitness levels with the Eurofit Test Battery, body composition with the Inbody 720 Body Composition Analyzer, cognitive attention with the Stroop Test, and dynamic balance with the Y-Balance Test. Read More

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http://dx.doi.org/10.1177/0031512520938517DOI Listing

Prevalence and Clinical Characteristics of the Restless Legs Syndrome (RLS) in Patients Diagnosed with Attention-Deficit Hyperactivity Disorder (ADHD) in Antioquia.

Int J Psychol Res (Medellin) 2018 Jan-Jun;11(1):58-69

Full member of the Colombian Association of Neurology (ACN) and Child Neurology Colombian Association (Asconi)-Group Director of Research in Child and Adolescent Disorders (PEDIACIENCIAS)-Titular Professor Department of Pediatrics, School of Medicine, Universidad de Antioquia, Medellín, Colombia. Universidad de Antioquia Department of Pediatrics School of Medicine Universidad de Antioquia Medellín Colombia.

Introduction: Attention Deficit Hyperactivity Disorder (ADHD) is the most common behavioral issue for children. One of the sleeping disorders most frequently related to ADHD is the Restless Legs Syndrome (RLS), characterized by an irresistible urge to move the legs, something that is generally associated with paresthesias and motor restlessness. The prevalence rate of RLS in children diagnosed with ADHD is close to 18%, but in Colombia, these cases have been hardly studied. Read More

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http://dx.doi.org/10.21500/20112084.3381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110177PMC

Attention Deficit Hyperactivity Disorder in Prisoners: Increased Substance Use Disorder Severity and Psychiatric Comorbidity.

Eur Addict Res 2020 Jul 2:1-12. Epub 2020 Jul 2.

Center for Evaluation and Sociomedical Research, Graduate School of Public Health, University of Puerto Rico, Rio Piedras, Puerto Rico, USA.

Objectives: Attention deficit hyperactivity disorder (ADHD) and substance use disorders (SUD) are overrepresented among incarcerated populations. We examined whether ADHD was associated with increased severity of comorbid SUD and with increased psychiatric comorbidity among prisoners.

Methods: Cross-sectional study of 500 randomly selected Latino male prisoners in the Puerto Rico Correctional System using validated diagnostic measures to assess Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5) ADHD and SUD diagnosis, antisocial personality disorder (ASP) and borderline personality disorder (BPD), major depression, and generalized anxiety disorder (GAD). Read More

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http://dx.doi.org/10.1159/000508829DOI Listing

Abnormal modulation of theta oscillations in children with attention-deficit/hyperactivity disorder.

Neuroimage Clin 2020 Jun 17;27:102314. Epub 2020 Jun 17.

State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China; Center for Collaboration and Innovation in Brain and Learning Sciences, Beijing Normal University, Beijing, China. Electronic address:

Previous studies have found that theta activities exhibit posterior lateralized modulation as well as midfrontal event-related synchronization (ERS) during covert visual attention in adults. The present study investigated whether these theta modulations existed in children and whether they were associated with attentional problems in attention-deficit/hyperactivity disorder (ADHD). Electroencephalography signals were recorded from typically developing (TD) children and children with ADHD (TD: n = 24; ADHD: n = 22) while they performed a cued covert visual attention task. Read More

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http://dx.doi.org/10.1016/j.nicl.2020.102314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330615PMC

Implementation of an attention training programme with a sample of children who have sustained traumatic brain injuries in South Africa: A pilot study.

Neuropsychol Rehabil 2020 Jul 2:1-29. Epub 2020 Jul 2.

ACSENT Laboratory, Department of Psychology, University of Cape Town, Rondebosch, South Africa.

This pilot study evaluated the feasibility of implementing an attention-training programme for children who have sustained moderate-to-severe traumatic brain injuries (TBIs) in a South African context. We compared the performance on the programme of children with TBI (TBI Intervention Group) to children who had been diagnosed with Attention Deficit Hyperactivity Disorder (ADHD Intervention Group), a TBI Art group and a TBI No-intervention Group (=5 in each group) in this preliminary study. Children in the two Intervention Groups participated in the "Pay Attention!" programme for 45 minutes twice a week for 12 weeks. Read More

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http://dx.doi.org/10.1080/09602011.2020.1782233DOI Listing

Use of Antipsychotics: The Experiences, Views, and Monitoring Practices of Child and Adolescent Psychiatrists in Turkey.

J Child Adolesc Psychopharmacol 2020 Jun 30. Epub 2020 Jun 30.

Department of Child and Adolescent Psychiatry, Manisa Celal Bayar University Faculty of Medicine, Manisa, Turkey.

The aim of this study is to evaluate the antipsychotics prescribed by child psychiatrists and their applications on the follow-up of these drugs. The universe of this research included consultant physicians and child psychiatry residents working in the field. A questionnaire has been created that assesses the use of antipsychotics and follow-up processes of physicians. Read More

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http://dx.doi.org/10.1089/cap.2020.0078DOI Listing

Epidemiology of Treatment for Preschoolers on Kentucky Medicaid Diagnosed with Attention-Deficit/Hyperactivity Disorder.

J Child Adolesc Psychopharmacol 2020 Jun 30. Epub 2020 Jun 30.

Department of Pediatrics, University of Louisville School of Medicine, Louisville, Kentucky, USA.

The National Survey of Children's Health reported a concerning increase in children 2-5 years being diagnosed with attention-deficit/hyperactivity disorder (ADHD) in 2016. Concerns include both the increase in diagnosing and potential deviations from published guidelines for the treatment of ADHD in preschoolers. The present study aims to describe the epidemiology and factors associated with receiving the diagnosis and treatment types for low-income preschoolers. Read More

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http://dx.doi.org/10.1089/cap.2020.0015DOI Listing

Relationship Between Illness Representations, Psychosocial Adjustment, and Treatment Outcomes in Mental Disorders: A Mini Review.

Front Psychol 2020 12;11:1167. Epub 2020 Jun 12.

Aix Marseille Univ, LPS, Aix-en-Provence, France.

Understanding and improving the psychosocial adjustments (e.g., quality of life, depression) and treatment outcomes (e. Read More

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http://dx.doi.org/10.3389/fpsyg.2020.01167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309516PMC

Magnesium Status in Children with Attention-Deficit/Hyperactivity Disorder and/or Autism Spectrum Disorder.

Soa Chongsonyon Chongsin Uihak 2020 Jan;31(1):41-45

Laboratory of Biotechnology and Applied Bioelementology, Yaroslavl State University, Yaroslavl, Russia.

Objective: The objective of this study was to assess serum, hair, and urinary magnesium (Mg) levels in children with attention-deficit/ hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and both ASD and ADHD to reveal potential interactive effects.

Methods: A total of 148 boys aged 4-9 years old were enrolled in this study, including 44 children with ADHD, 40 pediatric patients with ASD, 32 patients with both ADHD and ASD, as well as 32 healthy neurotypical children. Hair, serum, and urinary Mg levels were assessed using inductively-coupled plasma mass spectrometry (ICP-MS). Read More

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http://dx.doi.org/10.5765/jkacap.190036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324841PMC
January 2020

Development of the Korean Practice Parameter for Adult Attention-Deficit/Hyperactivity Disorder.

Soa Chongsonyon Chongsin Uihak 2020 Jan;31(1):5-25

Department of Psychiatry, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Objectives: Adult attention-deficit/hyperactivity disorder (ADHD) is an important mental health problem that needs resolution, especially considering the high rates of ADHD continuation from childhood to adolescence/adulthood and the high prevalence of ADHD in adults. Adults with ADHD have lifelong negative impacts and require close monitoring with long-term follow-up. Hence, the establishment of a Korean practice parameter for adult ADHD is necessary to minimize discontinuation of treatment and enable information sharing among Korean mental health professionals. Read More

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http://dx.doi.org/10.5765/jkacap.190030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324844PMC
January 2020

The Past Four Years Research Work of the Adult Attention-Deficit/Hyperactivity Disorder Special Interest Group in the Korean Academy of Child and Adolescent Psychiatry.

Authors:
Young Sik Lee

Soa Chongsonyon Chongsin Uihak 2020 Jan;31(1):3-4

Guest Editor, Chairman of Adult ADHD Special Interesting Group Department of Psychiatry, Chung-Ang University Hospital, Seoul, Korea.

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http://dx.doi.org/10.5765/jkacap.190031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324840PMC
January 2020

Clinical Profile of Tic Disorders in Children and Adolescents from a Tertiary Care Center in India.

Indian J Psychol Med 2020 May-Jun;42(3):262-267. Epub 2020 Apr 25.

Department of Child and Adolescent Psychiatry, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.

Background: Tic disorders (TDs) are common neurodevelopmental disorders in children and adolescents. To date, there is very scant literature on TDs in children and adolescents in the Indian setting.

Aim: The objectives of this study were to characterize the clinical profile, including comorbidities and pattern of medication use in the treatment of TDs, in children and adolescents. Read More

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http://dx.doi.org/10.4103/IJPSYM.IJPSYM_324_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320724PMC