118,157 results match your criteria Attachment & Human Development[Journal]


Fabrication and characterization of ultrathin spin-coated poly(L-lactic acid) films suitable for cell attachment and curcumin loading.

Biomed Mater 2020 Jul 8. Epub 2020 Jul 8.

SII Institute of Chemistry of New Materials of the National Academy of Sciences of Belarus, Minsk, BELARUS.

In the present study, ultrathin PLLA films were fabricated by spin-coating technique. Physico-chemical properties of the formed materials, including their morphology, thickness, transparency, contact angle, have been studied. We determined that morphology of PLLA films could be regulated by changing polymer concentration and humidity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1088/1748-605X/aba40aDOI Listing

Influenza A viruses use multivalent sialic acid clusters for cell binding and receptor activation.

PLoS Pathog 2020 Jul 8;16(7):e1008656. Epub 2020 Jul 8.

Laboratory of Experimental Biophysics, Institute of Physics, École Polytechnique Fédérale de Lausanne (EPFL), Route Cantonale, Lausanne, Switzerland.

Influenza A virus (IAV) binds its host cell using the major viral surface protein hemagglutinin (HA). HA recognizes sialic acid, a plasma membrane glycan that functions as the specific primary attachment factor (AF). Since sialic acid alone cannot fulfill a signaling function, the virus needs to activate downstream factors to trigger endocytic uptake. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.ppat.1008656DOI Listing

Marine medaka heat shock protein 90ab1 is a receptor for red-spotted grouper nervous necrosis virus and promotes virus internalization through clathrin-mediated endocytosis.

PLoS Pathog 2020 Jul 8;16(7):e1008668. Epub 2020 Jul 8.

School of Marine Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China.

Nervous necrosis virus (NNV) can infect many species of fish and causes serious acute or persistent infection. However, its pathogenic mechanism is still far from clear. Specific cellular surface receptors are crucial determinants of the species tropism of a virus and its pathogenesis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.ppat.1008668DOI Listing

An Angelman syndrome substitution in the HECT E3 ubiquitin ligase C-terminal Lobe of E6AP affects protein stability and activity.

PLoS One 2020 8;15(7):e0235925. Epub 2020 Jul 8.

Gustaf H. Carlson School of Chemistry and Biochemistry, Clark University, Worcester, MA, United States of America.

Angelman syndrome (AS) is a rare neurodevelopmental disorder characterized by speech impairment, intellectual disability, ataxia, and epilepsy. AS is caused by mutations in the maternal copy of UBE3A located on chromosome 15q11-13. UBE3A codes for E6AP (E6 Associated Protein), a prominent member of the HECT (Homologous to E6AP C-Terminus) E3 ubiquitin ligase family. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0235925PLOS

Adenovirus Mimetic Nanoparticles: Sequential Ligand-Receptor Interplay as a Universal Tool for Enhanced In Vitro/In Vivo Cell Identification.

ACS Appl Mater Interfaces 2020 Jul 8. Epub 2020 Jul 8.

Viral infection patterns often rely on precisely coordinated sequences of distinct ligand-receptor interactions, leading in many cases to an outstanding target cell specificity. A successful mimicry of viral targeting strategies to create more site-specific nanoparticles (NPs) would therefore require particle-cell interactions to also be adequately controllable. In the present study, hetero-multivalent block-copolymer NPs present their attached ligands in a sterically controlled manner to create a sequential NP-cell interaction similar to the cell infiltration strategy of human adenovirus type 2. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acsami.0c10057DOI Listing

Triceps-Sparing Total Elbow Arthroplasty for Distal Humerus Fracture: The Lateral Paraolecranon Approach.

Authors:
Michael H Amini

J Orthop Trauma 2020 Aug;34 Suppl 2:S9-S10

The CORE Institute, Mesa, AZ.

Distal humerus fractures in the elderly are a difficult problem to treat. Open reduction internal fixation has a high rate of complications, particularly because osteopenia compromises what is already tenuous fixation in a metaphyseal fracture. Total elbow arthroplasty is a more predictable outcome and easier recovery for these patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/BOT.0000000000001830DOI Listing

The Compassionate Kitbag: A creative and integrative approach to compassion-focused therapy.

Psychol Psychother 2020 Jul 8:e12291. Epub 2020 Jul 8.

Avon and Wiltshire Mental Health Partnership NHS Trust, Swindon, UK.

Purpose: This paper outlines the concept of the 'Compassionate Kitbag', a novel multi-sensory-based means of helping draw together the various elements of compassionate mind training and processes within compassion-focused therapy (CFT), to help clients cultivate and facilitate their capacities for compassion. Building on the work of Lucre and Corten (2013, Psychology and Psychotherapy: Theory, Research and Practice, 86, 387), this is the first published work exploring this concept and the theoretical underpinnings, with a specific focus on how this can be used to support people with attachment and relational trauma.

Methods: A narrative review of the literature on multi-sensory stimulation in facilitating people's capacities for compassion was conducted, coupled with a review of the literature of the use of non-human and transitional objects as explained by attachment theory and the broader scientific research underpinning the CFT model. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/papt.12291DOI Listing

What is best strategy for water soluble fluorescence dyes? - A case study using long fluorescence lifetime DAOTA dyes.

Chemistry 2020 Jul 8. Epub 2020 Jul 8.

University of Copenhagen, Nano-Science Center & Department of Chemistry, Universitetsparken 5, 2100, Copenhagen, DENMARK.

The lipophilic nature of organic dyes complicates their effectiveness in aqueous solutions. In this work we investigate three different strategies for achieving water-solubility of the diazaoxatriangulenium (DAOTA + ) chromophore: hydrophilic counter ions, aromatic sulfonation of the chromophore, and attachment of charged side chains. The long fluorescence lifetime (FLT, τ f = 20 ns) of DAOTA + makes it a sensitive probe to analyze solvation and aggregation effects. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/chem.202002457DOI Listing

Structural rearrangements as relaxation pathway for molecular negative ions formed via vibrational Feshbach resonance.

Phys Chem Chem Phys 2020 Jul 8. Epub 2020 Jul 8.

Institute of Molecule and Crystal Physics, Ufa Federal Research Centre, Russian Academy of Sciences, Prospekt Oktyabrya 151, 450075 Ufa, Russia.

The low-energy (0-15 eV) resonance electron interaction with two organic acids, oxaloacetic and α-ketoglutaric, is studied under gas-phase conditions using dissociative electron attachment spectroscopy. The most unexpected observation is the long-lived (microseconds) molecular negative ions formed by thermal electron attachment via the vibrational Feshbach resonance mechanism in both compounds. Unlike oxaloacetic acid, for which only one slow (microseconds) dissociative decay is detected, as many as five metastable negative ions are observed for α-ketoglutaric acid. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/d0cp02647fDOI Listing

A comparison of undergraduate teaching of psychiatry across medical schools in the Republic of Ireland.

Ir J Psychol Med 2020 Jun 8;37(2):77-88. Epub 2016 Jul 8.

Department of Psychiatry, Clinical Science Institute, National University of Ireland Galway, Galway, Ireland.

Objectives: To examine the delivery and assessment of psychiatry at undergraduate level in the six medical schools in the Republic of Ireland offering a medical degree programme.

Methods: A narrative description of the delivery and assessment of psychiatry at undergraduate level by collaborative senior faculty members from all six universities in Ireland.

Results: Psychiatry is integrated to varying degrees across all medical schools. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/ipm.2016.22DOI Listing

Evidence for preferential attachment: Words that are more well connected in semantic networks are better at acquiring new links in paired-associate learning.

Psychon Bull Rev 2020 Jul 7. Epub 2020 Jul 7.

College of Behavioral & Social Sciences, Southeastern University, Lakeland, FL, USA.

Here, we view the mental lexicon as a semantic network where words are connected if they are semantically related. Steyvers and Tenenbaum (Cognitive Science, 29, 41-78, 2005) proposed that the growth of semantic networks follows preferential attachment, the observation that new nodes are more likely to connect to preexisting nodes that are more well connected (i.e. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3758/s13423-020-01773-0DOI Listing

Functional role of respiratory supercomplexes in mice: SCAF1 relevance and segmentation of the Q.

Sci Adv 2020 Jun 24;6(26):eaba7509. Epub 2020 Jun 24.

Centro Nacional de Investigaciones Cardiovasculares Carlos III. Madrid 28029, Spain.

Mitochondrial respiratory complexes assemble into supercomplexes (SC). Q-respirasome (III + IV) requires the supercomplex assembly factor (SCAF1) protein. The role of this factor in the N-respirasome (I + III + IV) and the physiological role of SCs are controversial. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/sciadv.aba7509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314541PMC

Dynamic assessment of internal carotid artery and elongated styloid process in a case of bilateral carotid artery dissection.

Surg Neurol Int 2020 27;11:163. Epub 2020 Jun 27.

Department of Neurosurgery, Fukuoka University Hospital and School of Medicine, 7-45-1 Nanakuma Jonan-Ku, Fukuoka, Japan.

Background: Vascular Eagle syndrome is that an elongated styloid process causes ischemic stroke due to internal carotid artery (ICA) dissection. Dynamic assessment using radiological imaging has not been well investigated. We assessed the change in the relative positional relationship between the elongated styloid process and the ICA using a cone-beam computed tomography (CBCT). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.25259/SNI_42_2020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332696PMC

Strategies for Managing the Risk of Mucogingival Changes During Impacted Maxillary Canine Treatment.

Turk J Orthod 2020 Jun 1;33(2):123-132. Epub 2020 Jun 1.

Department of Periodontics, Faculty of Dental Medicine, Case Western Reserve University, Cleveland, Ohio, USA.

Gingival recession is a frequent mucogingival defect in the adult population. It affects the esthetics and is related to hypersensitivity and a high risk of periodontal attachment loss. The connection between orthodontic treatment and periodontal health has been debated for a long time. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5152/TurkJOrthod.2020.20038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316479PMC

Three-Dimensional Model of the Human Eye Development based on Computer Tomograph Images.

Curr Health Sci J 2020 Jan-Mar;46(1):31-38. Epub 2020 Mar 31.

Department of Automotive, Transportation and Industrial Engineering, Faculty of Mechanics, University of Craiova, Romania.

The objective of this study was to obtain a virtual biomechanical three dimensional model of the human eye though a multidisciplinary collaboration between researchers in various medical and informational fields in order to reach a better understanding of the optical performance of the healthy and diseased eye.

Material And Method: In order to obtain the virtual model, we analyzed the CT and MRI images of six patients, aged between 21 and 80 years old, dating from February 2013 until January 2019. These scans totalized 4226 images. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12865/CHSJ.46.01.05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323728PMC

Success of assisted reproductive technology treatment and couple relationship: A pilot study on the role of romantic attachment.

Health Psychol Open 2020 Jan-Jun;7(1):2055102920933073. Epub 2020 Jun 26.

Department of Dynamic and Clinical Psychology, Sapienza University of Rome, Rome, Italy.

Infertility is a deeply distressing experience, which can threaten important personal and martial goals, frequently affecting the psychophysical health. A supportive relationship and a secure romantic attachment appear to reduce infertility stress, as well as play a relevant role in the success of assisted reproductive technology treatments. The principal aim of the study is to investigate the predictive effect of romantic attachment, couple characteristics, quality of life and age on assisted reproductive technology outcome. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/2055102920933073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323283PMC

Enhanced Potency of a Broad H7N9-Neutralizing Antibody HNIgGA6 Through Structure-Based Design.

Front Microbiol 2020 19;11:1313. Epub 2020 Jun 19.

NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

H7N9 influenza virus was first isolated in 2013 and has caused five epidemic waves among humans to date. Treatment opinions are currently limited. Previously, we characterized a human neutralizing antibody, HNIgGA6, by isolating rearranged heavy- and light-chain genes from convalescent patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fmicb.2020.01313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316883PMC

Beta 1 integrin signaling mediates pancreatic ductal adenocarcinoma resistance to MEK inhibition.

Sci Rep 2020 Jul 7;10(1):11133. Epub 2020 Jul 7.

Department of Surgery, University of Michigan Cancer Center, University of Michigan, 1500 East Medical Center Drive, Cancer Center Room 6306, Ann Arbor, MI, 48109-0944, USA.

Pancreatic cancer, one of the deadliest human malignancies, has a dismal 5-year survival rate of 9%. KRAS is the most commonly mutated gene in pancreatic cancer, but clinical agents that directly target mutant KRAS are not available. Several effector pathways are activated downstream of oncogenic Kras, including MAPK signaling. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-020-67814-9DOI Listing

Systems biology of acidophile biofilms for efficient metal extraction.

Sci Data 2020 Jul 7;7(1):215. Epub 2020 Jul 7.

Centre for Ecology and Evolution in Microbial Model Systems, Linnaeus University, Kalmar, Sweden.

Society's demand for metals is ever increasing while stocks of high-grade minerals are being depleted. Biomining, for example of chalcopyrite for copper recovery, is a more sustainable biotechnological process that exploits the capacity of acidophilic microbes to catalyze solid metal sulfide dissolution to soluble metal sulfates. A key early stage in biomining is cell attachment and biofilm formation on the mineral surface that results in elevated mineral oxidation rates. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41597-020-0519-2DOI Listing

Immediate parent-infant skin-to-skin study (IPISTOSS): study protocol of a randomised controlled trial on very preterm infants cared for in skin-to-skin contact immediately after birth and potential physiological, epigenetic, psychological and neurodevelopmental consequences.

BMJ Open 2020 Jul 6;10(7):e038938. Epub 2020 Jul 6.

Women's and Children's Health, Karolinska Institute, Stockholm, Sweden.

Introduction: In Scandinavia, 6% of infants are born preterm, before 37 gestational weeks. Instead of continuing in the in-utero environment, maturation needs to occur in a neonatal unit with support of vital functions, separated from the mother's warmth, nutrition and other benefits. Preterm infants face health and neurodevelopment challenges that may also affect the family and society at large. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmjopen-2020-038938DOI Listing

Association between periodontitis and systemic lupus erythematosus: a meta-analysis.

Lupus 2020 Jul 7:961203320938447. Epub 2020 Jul 7.

The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, PR China.

Objective: The objective of this study was to explore the association between periodontitis and systemic lupus erythematosus (SLE).

Methods: To identify eligible studies, the PubMed, EMBASE and Web of Science databases were searched from inception to 19 September 2019. Associations of periodontitis, and other periodontal parameters, with SLE were assessed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0961203320938447DOI Listing

Food Security Challenges and Health Opportunities of Companion Animal Ownership for Low-Income Adults.

J Evid Based Soc Work (2019) 2020 Jul 7. Epub 2020 Jul 7.

Social Work, University of Pittsburgh , Pittsburgh, USA.

Purpose: Do pets provide benefits or risks for low-income individuals in regards to food security?

Method: Surveys of food security were administered to 392 low-income adults utilizing food pantries. Data collection included a self-administered questionnaire about demographics, food security, health and well-being, and for those with pets, animal attachment, commitment and animal information. Qualitative interviews were conducted with fifteen pet-owning individuals who completed the questionnaire and agreed to be contacted and interviewed over the phone about food security and their pets. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/26408066.2020.1781726DOI Listing

Electrospinning of bioactive polycaprolactone-gelatin nanofibres with increased pore size for cartilage tissue engineering applications.

J Biomater Appl 2020 Jul 7:885328220940194. Epub 2020 Jul 7.

TEMA, Department of Mechanical Engineering, University of Aveiro, Campus Universitário de Santiago, Aveiro, Portugal.

Polycaprolactone (PCL) electrospun scaffolds have been widely investigated for cartilage repair application. However, their hydrophobicity and small pore size has been known to prevent cell attachment, proliferation and migration. Here, PCL was blended with gelatin (GEL) combining the favorable biological properties of GEL with the good mechanical performance of the former. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0885328220940194DOI Listing

Three-Dimensional Radiographic Outcome of Free-Handed Flaplessly Placed Mini Dental Implants in Edentulous Maxillae after 2-Years Function.

J Clin Med 2020 Jul 5;9(7). Epub 2020 Jul 5.

Department of Periodontology and oral implantology, Oral and Maxillo-Facial Surgery, Dental Radiology, Ghent University Hospital, Corneel Heymanslaan 10, 9000 Ghent, Belgium.

Background: Free-handed, flaplessly placed mini dental implants (MDIs) are a valuable, more affordable and minimally invasive treatment to support overdentures in fully edentulous jaws, especially for medically compromised patients. However, critical 3D radiographic evaluation is lacking. This multicenter prospective case series assessed clinical outcome and carried out 3D- cone-beam computerized tomography (CBCT) analysis of free-handed flaplessly placed one-piece maxillary MDIs by an experienced maxillofacial surgeon. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/jcm9072120DOI Listing

Control of Particle Size in Flame Spray Pyrolysis of Tb-doped YO for Bio-Imaging.

Materials (Basel) 2020 Jul 4;13(13). Epub 2020 Jul 4.

Materials Architecturing Research Center, Korea Institute of Science & Technology, 5 Hwarang-ro 14-gil, Seongbuk-gu, Seoul 02792, Korea.

Recently, the use of oxide-based nanomaterials for bio-imaging has received great attention owing to their remarkable stabilities as compared to those of conventional organic dyes. Therefore, the development of scalable methods for highly luminescent oxide materials with fine control of size has become crucial. In this study, we suggested modified flame spray pyrolysis (FSP) as a scalable method to produce a green-light emitting phosphor-Tb-doped YO-in the nanometer size range. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ma13132987DOI Listing

Use of Platelet-Rich Fibrin in the Treatment of Grade 2 Furcation Defects: Systematic Review and Meta-Analysis.

J Clin Med 2020 Jul 3;9(7). Epub 2020 Jul 3.

Department of Life, Health and Environmental Sciences, University of L'Aquila, Piazzale Salvatore Tommasi 1, 67100 L'Aquila, Coppito, Italy.

In periodontitis patients, furcation defects are crucial sites to regenerate due to their complex anatomy. Various modern surgical techniques and use of biomaterials have been suggested in the literature. Among all, platelet-rich fibrin (PRF) has potential in tissue regeneration thanks to its role in the release of growth factors. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/jcm9072104DOI Listing

The OXTR polymorphisms are not associated with attachment dimensions: A three-approach study.

Psychoneuroendocrinology 2020 Jun 21;120:104780. Epub 2020 Jun 21.

College of Life Science, Northwest University, Xi'an, 710069, China.

Inspired by the roles of oxytocin in social behaviors, scientists have devoted considerable efforts to examine the association between the oxytocin receptor gene (OXTR) and human attachment, a personality of seek and receiving comfort from intimate figures. However, there are still a lot of controversies on the association. To clarify the relationship, this research integrated three studies: (1) A cross-sectional study indicated that the OXTR polymorphisms (i. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.psyneuen.2020.104780DOI Listing

Facile strategy for immobilizing horseradish peroxidase on a novel acetate functionalized ionic liquid/MWCNT matrix for electrochemical biosensing.

Int J Biol Macromol 2020 Jul 4. Epub 2020 Jul 4.

Department of Chemistry, School of Advanced Sciences, Vellore Institute of Technology (VIT), Vellore 632014, India. Electronic address:

Facile yet simple platforms for the immobilization of biomolecules have always been a substantial requirement for the fabrication of proficient biosensors. In this study, we report a naphthyl substituted acetate functionalized ionic liquid (NpAc-IL) for the covalent anchoring of horseradish peroxidase (HRP), using which the direct electrochemistry of HRP was successfully accomplished and a HO biosensor was developed. The naphthyl substitution on the NpAc-IL was utilized for the π-π stacking with the MWCNT modified GCE and the terminal -OCH group of NpAc-IL was used for the covalent attachment with the free -NH group of HRP via amide bond formation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijbiomac.2020.07.005DOI Listing

Prognostic Factors for Outcome after Vitrectomy for Retinal Detachment Secondary to Cytomegalovirus Retinitis in Patients with AIDS: A Retrospective Single-center Analysis.

Ocul Immunol Inflamm 2020 Jul 7:1-6. Epub 2020 Jul 7.

Department of Opthalmology, Beijing Tongren Hosptial, Capital Medical University, Beijing, China.

: To analyze the clinical characteristics and relevant prognostic factors of vitrectomy for retinal detachment (RD) secondary to cytomegalovirus retinitis (CMVR) in patients with acquired immune deficiency syndrome (AIDS).: This study involved 39 eyes that underwent vitrectomy. Best-corrected visual acuity (BCVA), CD4 cell counts, retinal attachment rate, and prognostic factors were assessed 1, 3, and 6 months postoperatively. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/09273948.2020.1764591DOI Listing

Characterization of Lysozyme PEGylation products using polarized Excitation Emission Matrix (pEEM) spectroscopy.

Biotechnol Bioeng 2020 Jul 7. Epub 2020 Jul 7.

Nanoscale BioPhotonics Laboratory, School of Chemistry, National University of Ireland, Galway, Galway, H91 CF50, Ireland.

The growing use of therapeutic proteins requires accurate measurement techniques for measuring biophysical and structural changes during manufacturing. This is particularly true for PEGylation of proteins, because characterization of PEGylation reactions and products can often be difficult because of the relatively small impact on protein structure, the lack of an accessible PEG chromophore, and the heterogeneous final product mixtures. Intrinsic fluorescence spectroscopy is one potential solution because of its relatively high sensitivity to small changes in protein structure and its suitability for online or at-line measurements. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/bit.27483DOI Listing

Long-armed hexapod nanocrystals of cesium lead bromide.

Nanoscale 2020 Jul 7. Epub 2020 Jul 7.

Institute for Chemical and Bioengineering, Department of Chemistry and Applied Biosciences, ETH Zürich, Vladimir Prelog Weg 1, 8093 Zürich, Switzerland.

Colloidal lead halide perovskite nanocrystals (LHP NCs) assume a variety of morphologies (e.g. cubes, sheets, and wires). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/d0nr02985hDOI Listing

In vitro assessment of the antimicrobial efficacy of chitosan nanoparticles against major fish pathogens and their cytotoxicity to fish cell lines.

J Fish Dis 2020 Jul 6. Epub 2020 Jul 6.

Clinical Division of Fish Medicine, University of Veterinary Medicine, Vienna, Austria.

Nanotechnology is an emerging avenue employed in disease prevention and treatment. This study evaluated the antimicrobial efficacy of chitosan nanoparticles (CSNPs) against major bacterial and oomycete fish pathogens in comparison with chitosan suspension. Initially, the minimum inhibitory concentrations (MIC, MIC ) were determined and the per cent inhibition of bacterial growth was calculated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jfd.13212DOI Listing

Cell Adhesion Assay to Study Leptospiral Proteins: An Approach to Investigate Host-Pathogen Interaction.

Methods Mol Biol 2020 ;2134:171-185

Laboratorio de Desenvolvimento de Vacinas-Centro de Biotecnologia, Instituto Butantan, Sao Paulo, Brazil.

The adhesion of pathogenic bacteria to host cells and the extracellular matrix (ECM) is considered an important step in the pathogenesis of microorganisms. It has been described that Leptospira spp. bind to multiple receptors on host cells and to the ECM to initiate infection. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-0716-0459-5_16DOI Listing
January 2020

Myxoid mesenchymal intraventricular brain tumour with EWSR1-CREB1 gene fusion in an adult woman.

Virchows Arch 2020 Jul 6. Epub 2020 Jul 6.

Neurosurgery Department, Centro Hospitalar Universitário São João, Porto, Portugal.

Myxoid mesenchymal tumours harbouring fusions between EWSR1 and the CREB family transcription factors have recently been described. Whether they represent a novel entity or a myxoid variant of angiomatoid fibrous histiocytoma (AFH) remains a matter of debate. We describe the case of a 58-year-old woman with a previous history of breast cancer that developed progressive neurological decline due to a large mass located in the left lateral ventricle of the brain. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00428-020-02885-7DOI Listing

Dataset of ex-pat teachers in Southeast Asia's intention to leave due to the COVID-19 pandemic.

Data Brief 2020 Aug 23;31:105913. Epub 2020 Jun 23.

University of Labour and Social Affairs, Hanoi, 100000, Vietnam.

The COVID-19 pandemic exerted an adverse influence on the global education system, especially since starting school lockdown. The growth of teacher unemployment figures climbed double-digit and spawned these unexpected sequels. For instance, while native teachers seemed indisposed to leave the profession with the aim of seeking another more profited and seasonal jobs, many ex-pat teachers presented themselves with moving or stayed dilemma in the way the government salvaged their situation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.dib.2020.105913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309813PMC

[Parental Factors Associated with Smartphone Overuse in Preschoolers: A Systematic Review and Meta-Analysis].

J Korean Acad Nurs 2020 Jun;50(3):349-368

College of Nursing, Seoul National University, Seoul, Korea.

Purpose: This study aimed to identify parental factors associated with smartphone overuse in preschoolers.

Methods: A systematic review was conducted according to PRISMA guidelines. Relevant studies published in peer-reviewed journals from 2009 to June 2019 were identified through systematic search in 10 electronic databases (PubMed, CINAHL, Cochrane Central, EMBASE, Web of Science, NDSL, KISS, KMbase, KoreaMed, and RISS). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4040/jkan.19186DOI Listing

Attachment Style, Complicated Grief and Post-Traumatic Growth in Traumatic Loss: The Role of Intrusive and Deliberate Rumination.

Psychiatry Investig 2020 Jul 8. Epub 2020 Jul 8.

Department of Psychiatry, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Republic of Korea.

Objective: The present study examines the effects of attachment styles on the grief response and the indirect effect of rumination in parents who lost a child in the Sewol Ferry accident.

Methods: Bereaved parents (n=81) completed self-report questionnaires evaluating their attachment style (Experience in Close Relationship-Short form), traumatic loss related rumination (Event-Related Rumination Inventory), degree of complicated grief (Inventory of Complicated Grief), and post-traumatic growth (Post-Traumatic Growth Inventory). Data were analyzed using correlation analysis, structural equation modeling, and bootstrapping. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.30773/pi.2019.0291DOI Listing

Botulinum Toxin and Neuronal Regeneration after Traumatic Injury of Central and Peripheral Nervous System.

Authors:
Siro Luvisetto

Toxins (Basel) 2020 Jul 2;12(7). Epub 2020 Jul 2.

Institute of Biochemistry and Cell Biology, National Research Council of Italy, via Ramarini 32, Monterotondo Scalo, 00015 Rome, Italy.

Botulinum neurotoxins (BoNTs) are toxins produced by the bacteria , the causing agent for botulism, in different serotypes, seven of which (A-G) are well characterized, while others, such as H or FA, are still debated. BoNTs exert their action by blocking SNARE (soluble N-ethylmale-imide-sensitive factor-attachment protein receptors) complex formation and vesicle release from the neuronal terminal through the specific cleavage of SNARE proteins. The action of BoNTs at the neuromuscular junction has been extensively investigated and knowledge gained in this field has set the foundation for the use of these toxins in a variety of human pathologies characterized by excessive muscle contractions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/toxins12070434DOI Listing

Features of the Human Antibody Response against the Respiratory Syncytial Virus Surface Glycoprotein G.

Vaccines (Basel) 2020 Jun 25;8(2). Epub 2020 Jun 25.

Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090 Vienna, Austria.

Respiratory syncytial virus (RSV) infections are a major cause of serious respiratory disease in infants. RSV occurs as two major subgroups A and B, which mainly differ regarding the surface glycoprotein G. The G protein is important for virus attachment and G-specific antibodies can protect against infection. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/vaccines8020337DOI Listing

When a Head Is about to Burst: Attachment Mediates the Relationship Between Childhood Trauma and Migraine.

Int J Environ Res Public Health 2020 Jun 25;17(12). Epub 2020 Jun 25.

Olomouc University Social Health Institute, Palacky University Olomouc, 771 11 Olomouc, Czech Republic.

Background: People exposed to childhood trauma show insecure attachment patterns and are more prone to chronic and pain-related conditions, including migraine. The aim of this study was to explore the mediating role of attachment in the association between childhood trauma and adulthood chronic health conditions, with a focus on migraine.

Methods: Respondents from a representative sample of citizens of the Czech Republic ( = 1800, mean age: 46. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijerph17124579DOI Listing

The Disease Process, Diagnosis and Treatment of Invasive Cervical Resorption: A Review.

Dent J (Basel) 2020 Jul 1;8(3). Epub 2020 Jul 1.

Columbia University College of Dental Medicine Division of Endodontics, Columbia University, New York, NY 10032, USA.

Invasive cervical resorption (ICR) is a localized, subepithelial, supra-osseous resorptive process of the tooth. Although there are several predisposing factors associated with ICR, its etiology and pathogenesis are poorly understood. The damage to the protective layer on the external root surface appears to allow for the attachment of clastic cells and initiate the resorptive process, which is confined by the inner protective pericanalar resorption-resistant sheet surrounding the root canal space. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/dj8030064DOI Listing

Vimentin as a Multifaceted Player and Potential Therapeutic Target in Viral Infections.

Int J Mol Sci 2020 Jun 30;21(13). Epub 2020 Jun 30.

Department of Structural and Chemical Biology, Centro de Investigaciones Biológicas Margarita Salas, CSIC, Ramiro de Maeztu, 9, 28040 Madrid, Spain.

Vimentin is an intermediate filament protein that plays key roles in integration of cytoskeletal functions, and therefore in basic cellular processes such as cell division and migration. Consequently, vimentin has complex implications in pathophysiology. Vimentin is required for a proper immune response, but it can also act as an autoantigen in autoimmune diseases or as a damage signal. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms21134675DOI Listing

Mutations at the Serine Hydroxymethyltransferase Impact its Interaction with a Soluble NSF Attachment Protein and a Pathogenesis-Related Protein in Soybean.

Vaccines (Basel) 2020 Jun 30;8(3). Epub 2020 Jun 30.

Department of Plant, Soil and Agricultural Systems, Southern Illinois University, Carbondale, IL 62901, USA.

Resistance to soybean cyst nematodes (SCN) in "Peking-type" resistance is bigenic, requiring and . encodes a serine hydroxymethyltransferase (GmSHMT08) and encodes a soluble NSF attachment protein (GmSNAP18). Recently, it has been shown that a pathogenesis-related protein, GmPR08-Bet VI, potentiates the interaction between GmSHMT08 and GmSNAP18. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/vaccines8030349DOI Listing

Sugary Logistics Gone Wrong: Membrane Trafficking and Congenital Disorders of Glycosylation.

Int J Mol Sci 2020 Jun 30;21(13). Epub 2020 Jun 30.

Tumor Immunology Lab, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Geert Grooteplein 28, 6525 GA Nijmegen, The Netherlands.

Glycosylation is an important post-translational modification for both intracellular and secreted proteins. For glycosylation to occur, cargo must be transported after synthesis through the different compartments of the Golgi apparatus where distinct monosaccharides are sequentially bound and trimmed, resulting in increasingly complex branched glycan structures. Of utmost importance for this process is the intraorganellar environment of the Golgi. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms21134654DOI Listing

Fault Detection, Isolation, Identification and Recovery (FDIIR) Methods for Automotive Perception Sensors Including a Detailed Literature Survey for Lidar.

Sensors (Basel) 2020 Jun 30;20(13). Epub 2020 Jun 30.

VIRTUAL VEHICLE Research GmbH, Inffeldgasse 21a, 8010 Graz, Austria.

Perception sensors such as camera, radar, and lidar have gained considerable popularity in the automotive industry in recent years. In order to reach the next step towards automated driving it is necessary to implement fault diagnosis systems together with suitable mitigation solutions in automotive perception sensors. This is a crucial prerequisite, since the quality of an automated driving function strongly depends on the reliability of the perception data, especially under adverse conditions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/s20133662DOI Listing

Experimental and Theoretical Study of the Covalent Grafting of Triazole Layer onto the Gold Surface.

Materials (Basel) 2020 Jun 30;13(13). Epub 2020 Jun 30.

Department of Chemistry, Faculty of Science and Technology, Umeå University, SE 90187 Umeå, Sweden.

Finding novel strategies for surface modification is of great interest in electrochemistry and material sciences. In this study, we present a strategy for modification of a gold electrode through covalent attachment of triazole (TA) groups. Triazole groups were electrochemically grafted at the surface of the electrode by a reduction of in situ generated triazolediazonium cations. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ma13132927DOI Listing

Conserved Oligomeric Golgi (COG) Complex Proteins Facilitate Orthopoxvirus Entry, Fusion and Spread.

Viruses 2020 Jun 30;12(7). Epub 2020 Jun 30.

Poxvirus and Rabies Branch, Centers for Disease Control and Prevention, Atlanta, GA 3033, USA.

Although orthopoxviruses (OPXV) are known to encode a majority of the genes required for replication in host cells, genome-wide genetic screens have revealed that several host pathways are indispensable for OPXV infection. Through a haploid genetic screen, we previously identified several host genes required for monkeypox virus (MPXV) infection, including the individual genes that form the conserved oligomeric Golgi (COG) complex. The COG complex is an eight-protein (COG1-COG8) vesicle tethering complex important for regulating membrane trafficking, glycosylation enzymes, and maintaining Golgi structure. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/v12070707DOI Listing

Influence of Herbal Medicines on HMGB1 Release, SARS-CoV-2 Viral Attachment, Acute Respiratory Failure, and Sepsis. A Literature Review.

Int J Mol Sci 2020 Jun 30;21(13). Epub 2020 Jun 30.

Department of Medicinal and Cosmetic Natural Products, Poznan University of Medicinal Sciences, Mazowiecka 33, 60-623 Poznan, Poland.

By attaching to the angiotensin converting enzyme 2 (ACE2) protein on lung and intestinal cells, Sudden Acute Respiratory Syndrome (SARS-CoV-2) can cause respiratory and homeostatic difficulties leading to sepsis. The progression from acute respiratory failure to sepsis has been correlated with the release of high-mobility group box 1 protein (HMGB1). Lack of effective conventional treatment of this septic state has spiked an interest in alternative medicine. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms21134639DOI Listing

Spontaneous Differentiation of Human Neural Stem Cells on Nanodiamonds.

Adv Biosyst 2019 Apr 19;3(4):e1800299. Epub 2019 Mar 19.

London Centre for Nanotechnology and Department of Electronic and Electrical Engineering, University College London, 17-19 Gordon Street, London, WC1H 0AH, UK.

The potential use of stem cells in regenerative medicine requires the ability to be able to control stem cell fate as cellular networks are developed. Here, nanodiamonds (≈10 nm) are supported on glass and shown to be an excellent host for the attachment and proliferation of human neural stem cells. Moreover, it is shown that spontaneous differentiation into neurons occurs on nanodiamonds. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/adbi.201800299DOI Listing

Microscaffolds by Direct Laser Writing for Neurite Guidance Leading to Tailor-Made Neuronal Networks.

Adv Biosyst 2019 May 7;3(5):e1800329. Epub 2019 Mar 7.

Center for Hybrid Nanostructures (CHyN), Universität Hamburg, Luruper Chaussee 149, Hamburg, 22761, Germany.

While modern day integrated electronic circuits are essentially designed in a 2D fashion, the brain can be regarded as a 3D circuit. The thus enhanced connectivity enables much more complex signal processing as compared to conventional 2D circuits. Recent technological advances in the development of nano/microscale 3D structuring have led to the development of artificial neuron culturing platforms, which surpass the possibilities of classical 2D cultures. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/adbi.201800329DOI Listing