Search our Database of Scientific Publications and Authors

I’m looking for a

    100 results match your criteria Atrophoderma of Pasini and Pierini

    1 OF 2

    Crossed Total Hemiatrophy Associated with Atrophoderma of Pasini-Pierini.
    Skinmed 2017 1;15(3):227-229. Epub 2017 Jun 1.
    Department of Dermatology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China;
    A 45-year-old Chinese man had begun to show asymmetry of the face 30 years previously. Subsequently, he developed visual extinction of the right eye, slight numbness, and weakness of the left extremities. Simultaneously, multiple atrophic brownish patches occurred on his side. Read More

    Idiopathic atrophoderma of Pasini and Pierini: A case study of collagen and elastin texture by multiphoton microscopy.
    J Am Acad Dermatol 2017 Nov 25;77(5):930-937. Epub 2017 Apr 25.
    Biophotonics Group, Department of Quantum Electronics, Institute of Physics Gleb Wataghin, University of Campinas, Campinas, Brazil; National Institute of Science and Technology on Photonics Applied to Cell Biology, University of Campinas, Campinas, Brazil; Department of Physics, Federal University of Ceara, Fortaleza, Brazil.
    Background: The diagnosis of idiopathic atrophoderma of Pasini and Pierini (IAPP) relies on typical clinical features, particularly distinctive pigmented ovular/round depressed plaques. Histologic examination often reveals no obvious changes, but patterns of collagen distribution, using multiphoton imaging and second harmonic generation can help track hidden details of tissue organization contributing to atrophy.

    Objective: To identify histologic features that distinguish IAPP from unaffected skin. Read More

    Linear atrophoderma of Moulin: an underrecognized entity.
    Pediatr Rheumatol Online J 2015 Oct 6;13(1):39. Epub 2015 Oct 6.
    Division of Dermatology, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, 1001 Boulevard Décarie, Montreal, QC, H4A 3J1, Canada.
    Linear atrophoderma of Moulin (LAM) is an acquired skin condition that manifests in early childhood and adolescence. It likely represents a form of cutaneous mosaicism that presents with linear, hyperpigmented and atrophic lesions appearing on the trunk and limbs. Its clinical appearance varies and may closely resemble that of atrophoderma of Pasini and Pierini (APP) and linear scleroderma. Read More

    Generalized lenticular atrophoderma of Pasini and Pierini.
    Pediatr Dermatol 2015 May-Jun;32(3):389-91. Epub 2014 Sep 18.
    Department of Dermatology, Hospital das Clínicas, University of São Paulo, São Paulo, Brazil.
    We present a 16-year-old boy with multiple, well-circumscribed, atrophic, light-brown patches on his neck, chest, and back. The authors believe that it represents an unusual presentation of atrophoderma of Pasini and Pierini and suggest the designation "generalized lenticular APP." Read More

    Case for diagnosis.
    An Bras Dermatol 2014 Jul-Aug;89(4):671-3
    SES, Regional Hospital of Asa Norte, Brasília, DF, Brazil.
    Idiopathic Atrophoderma of Pasini and Pierini (IAPP) is a rare, exclusively cutaneous disease. It is more frequent in females, with incidence peak in the second and third decades of life. The etiopathogenesis remains unknown. Read More

    Diagnosis and management of morphea and lichen sclerosus and atrophicus in children.
    Pediatr Clin North Am 2014 Apr 27;61(2):309-19. Epub 2013 Dec 27.
    Departments of Paediatrics and Medicine, The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, ON M5G 1X8, Canada.
    Morphea (localized scleroderma) is a rare fibrosing disorder of the skin and underlying tissues characterized by skin thickening and hardening due to increased collagen deposition. The significance of the disease depends on the extent of the lesions, potential for functional disability or cosmetic disfigurement, and presence or absence of extracutaneous manifestations. Treatment is tailored; circumscribed forms may require only topical treatment, while forms causing functional impairment or severe cosmetic change may require systemic treatment. Read More

    Update on the classification and treatment of localized scleroderma.
    Actas Dermosifiliogr 2013 Oct 13;104(8):654-66. Epub 2013 Aug 13.
    Servicio de Dermatología, Hospital Universitari Germans Trias i Pujol, Universidad Autónoma de Barcelona, Barcelona, Spain. Electronic address:
    Morphea or localized scleroderma is a distinctive inflammatory disease that leads to sclerosis of the skin and subcutaneous tissues. It comprises a number of subtypes differentiated according to their clinical presentation and the structure of the skin and underlying tissues involved in the fibrotic process. However, classification is difficult because the boundaries between the different types of morphea are blurred and different entities frequently overlap. Read More

    Linear atrophoderma of Moulin: a distinct entity?
    Pediatr Dermatol 2014 May-Jun;31(3):373-7. Epub 2012 Oct 9.
    School of Medicine, Medical College of Georgia, Georgia Health Sciences University, Augusta, Georgia.
    Linear atrophoderma of Moulin (LAM) is a rare dermatologic disorder characterized by a hyperpigmented atrophoderma that consistently follows the lines of Blaschko. There are many clinical and histologic similarities between LAM, atrophoderma of Pasini and Pierini (APP), and morphea, and whether LAM represents part of a disease spectrum or its own distinct entity is debated. This case of a 16-year-old boy with LAM supports the hypothesis that LAM, APP, and morphea are a spectrum of disorders rather than unique entities. Read More

    Congenital idiopathic atrophoderma of Pasini and Pierini.
    Dermatol Online J 2012 Apr 15;18(4). Epub 2012 Apr 15.
    University of Miami, Miami, Florida, USA.
    Idiopathic atrophoderma of Pasini and Pierini is a disorder of dermal atrophy. There is a female predominance and almost never does the condition present at birth. Histopathological examination reveals attenuated dermis. Read More

    Linear atrophoderma of Moulin on the neck.
    J Dermatol Case Rep 2011 Sep;5(3):47-9
    Sisli Etfal Education and Training Hospital, Dermatology Department, Sisli/Istanbul, Turkey.
    Background: Linear atrophoderma is a rare disease, first described by Moulin in 1992 in 5 patients. It is an acquired unilateral hyperpigmented, depressed band-like areas following the lines of Blaschko. It affects children or adolescents of both genders involving the trunk or the limbs. Read More

    Presence of Borrelia burgdorferi "Sensu Lato" in patients with morphea from the Amazonic region in Brazil.
    Int J Dermatol 2011 Nov;50(11):1373-8
    Department of Dermatology, Fundação de Medicina Tropical do Amazonas, Amazonas, Brazil.
    Background: In the present study, Borrelia spirochetes were found in four (26.6%) out of 15 patients with Atrophoderma of Pasini and Pierini (IAPP) and lichen sclerosis et atrophicans (LSA) from the Brazilian Amazon Region.

    Material And Methods: Borreliosis was investigated by immunohistochemistry and focus floating microscopy for Borrelia burgdorferi in skin biopsy samples from 15 patients with both clinical and histopathology evidences compatible with Morphea, LSA, and IAPP. Read More

    A Case of Atrophoderma of Pasini and Pierini Associated with Borrelia burgdorferi Infection Successfully Treated with Oral Doxycycline.
    Ann Dermatol 2011 Aug 6;23(3):352-6. Epub 2011 Aug 6.
    Department of Dermatology, Yonsei University Wonju College of Medicine, Wonju, Korea.
    Atrophoderma of Pasini and Pierini is a form of dermal atrophy that manifests as either single or multiple, sharply demarcated, hyperpigmented, non-indurated patches. These patches are marked by a slight depression of the skin, with an abrupt edge (i.e. Read More

    Two uncommon cases of idiopathic atrophoderma of pasini and pierini: multiple and giant.
    Indian J Dermatol Venereol Leprol 2011 May-Jun;77(3):402
    Department of Dermatology, First Affiliated Hospital, Nanjing Medical University, Nanjing, China.
    We report a 39-year-old Chinese man presenting with approximately 200 atrophic brownish patches for 10 years, whose clinical manifestation and pathological features were consistent with the findings of idiopathic atrophoderma of Pasini and Pierini. Another described case was a 62-year-old woman who had a gradually increasing asymptomatic hyperpigmented and depressed patch on her right lumbosacral region over a period of 7 years. At the time of consultation, the size of the lesion was approximately 27 x 23 cm. Read More

    Exacerbated course of atrophoderma of Pasini and Pierini in patient with papillary cancer of the thyroid gland.
    Wiad Lek 2010 ;63(1):24-6
    Katedra i Klinika Chorób Wewnetrznych i Reumatologii Slaskiego Uniwersytetu Medycznego w Katowicach.
    Atrophoderma of Pasini and Pierini is a benign cutaneous atrophy skin to morphea en plaques on repression and is considered as systemic sclerosis-like disorder. A case of female patient with atrophoderma of Pasini and Pierini in whom rapid eruption of new plaques was found after many years of stable disease in described. Papillary cancer of the thyroid gland was diagnosed and acceleration of atrophoderma should be considered as paraneoplastic syndrome. Read More

    A teen-ager with linear atrophoderma of Moulin.
    Dermatol Online J 2010 Feb 15;16(2). Epub 2010 Feb 15.
    Unit of Dermatology, Oasi Institute (IRCCS), Troina, Italy.
    Linear atrophoderma, first described by Moulin, is an acquired unilateral dermatitis localized along the Blaschko lines. It affects children or adolescents of both genders, involving the trunk and the limbs. It is, presumably, a rare cutaneous form of mosaicism. Read More

    Localized scleroderma: a series of 52 patients.
    Eur J Intern Med 2009 May 17;20(3):331-6. Epub 2008 Sep 17.
    Department of Internal Medicine Centre Hospitalo-Universitaire Saint-Antoine, 75012 Paris, Assistance Publique/Hôpitaux de Paris, France.
    Background: Localized scleroderma also called morphea is a skin disorder of undetermined cause. The widely recognized Mayo Clinic Classification identifies 5 main morphea types: plaque, generalized, bullous, linear and deep. Whether each of these distinct types has a particular clinical course or is associated with some patient-related features is still unclear. Read More

    [Type I and II collagens and mast cells expression in the skin lesions from the patients with localized scleroderma].
    Przegl Lek 2008 ;65(4):161-5
    Katedra i Klinika Dermatologii, Collegium Medicum, Uniwersytet Jagielloński, Kraków.
    Morphea en plaques (MP) and atrophoderma Pasini-Pierini (APP) are by most researchers regarded as specific types of localized scleroderma (LS), but their clinical picture is completely different. Fibrosing process is very complicated, and is connected with presence of collagen (I and III type) and extracellulare matrix deposits in the dermis. Probably mast cells also play an important role in this process. Read More

    Atrophoderma of Pasini and Pierini: a clinical and histopathological study.
    J Cutan Pathol 2008 Dec 18;35(12):1108-14. Epub 2008 Jun 18.
    Department of Dermatology, American University of Beirut Medical Center, Beirut, Lebanon.
    Background: Idiopathic atrophoderma of Pasini and Pierini (IAPP) usually manifests as one or multiple depressed and hyperpigmented patches, with a predilection to the trunk. No diagnostic changes are usually seen on histology. Elastic stains often reveal no abnormalities. Read More

    Congenital atrophoderma of Pasini and Pierini.
    J Korean Med Sci 2006 Feb;21(1):169-71
    Department of Dermatology, Ajou University School of Medicine, Suwon, Korea.
    Idiopathic atrophoderma of Pasini and Pierini is a form of dermal atrophy of unknown etiology, usually affecting women during their adolescence and young adulthood. A 2-yr-old girl was presented with erythematous atrophic lesion on the right shoulder, which appeared from birth. The histologic findings were consistent with atrophoderma. Read More

    [Idiopathic atrophoderma of Pasini and Pierini. Study of 4 cases].
    Actas Dermosifiliogr 2005 Jun;96(5):303-6
    Sección de Dermatología, Hospital Nuestra Señora de Sonsoles, Castilla 1, 1.o-1.a, 05005 Avila, Spain.
    Idiopathic atrophoderma of Pasini and Pierini (IAPP) is an infrequent form of cutaneous atrophy, of unknown etiology. We describe the clinical and histological symptoms of four women with IAPP. Three of them had lesions on the back, while the fourth had them on the buttocks. Read More

    Unilateral congenital linear atrophoderma of the leg.
    Pediatr Dermatol 2005 Jul-Aug;22(4):350-4
    Jefferson Medical College, Department of Dermatology and Cutaneous Biology, Philadelphia, Pennsylvania 19107, USA.
    We report an infant with depressed, hypopigmented, linear plaques of congenital onset on the lower extremity. The lesions were asymptomatic and the child was otherwise healthy. Despite the clinically obvious change in skin texture and color, histopathologic changes were subtle: a biopsy specimen showed hypopigmentation and a decrease in elastic fibers in the papillary and upper reticular dermis. Read More

    [Presence of the antinuclear antibodies and antibodies to Borrelia burgdorferi among patients with morphea en plaque, deep linear scleroderma and atrophoderma Pasini-Pierini].
    Przegl Lek 2002 ;59(11):898-902
    Klinika Dermatologii i Wenerologii Collegium Medicum Uniwersytetu Jagiellońskiego, Kraków.
    Circumscribed scleroderma belongs to the groups of the diseases characterized by fibrosis of the skin and the deeper tissue. According to the published data, 47% to 76% patients with circumscribed scleroderma present antinuclear antibodies (ANA) as well as antibodies to Borrelia burgdorferi which is believed to be causative factor of the disease. The study was conducted in the group of 50 consecutive patients with circumscribed sclerosis (en plaque, deep linear, atrophoderma Pasini-Pierini). Read More

    Morphoea in three siblings.
    J Eur Acad Dermatol Venereol 2001 Jan;15(1):46-7
    Servei de Dermatologia, Hospital Clinic, Universitat de Barcelona, IDIBAPS Barcelona, Villaroel, Spain.
    Atrophoderma of Pasini and Pierini (APP) is an uncommon form of localized morphoea that occurs as superficial, hyperpigmented plaques distributed mainly on the trunk and proximal part of the limbs. There is little information about the influence of genetic and environmental factors on disease susceptibility and expression for localized scleroderma, although APP familial cases have been reported. We report three siblings without a family history of autoimmune disease presenting cutaneous lesions suggesting morphoea (APP variant). Read More

    Linear atrophoderma of Moulin.
    Eur J Dermatol 2000 Dec;10(8):611-3
    Department of Dermatology, Klinikum Kassel, Mönchebergstr. 41-43 D - 34125 Kassel Germany.
    We report a typical case of linear atrophoderma of Moulin that represents a distinct clinical entity. A 17-year-old woman presented with hyperpigmented and atrophic band-like skin lesions measuring 3-5 cm in breadth on the right side of her trunk and on the right buttock, in an arrangement following the system of Blaschko's lines. The skin lesions had a normal texture and showed no signs of inflammation, lilac ring, erythema, induration, sclerosis or depigmentation. Read More

    Treatment of atrophoderma of Pasini and Pierini-associated hyperpigmentation with the Q-switched alexandrite laser: a clinical, histologic, and ultrastructural appraisal.
    Lasers Surg Med 2000 ;27(3):206-12
    Department of Dermatology, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA.
    Background And Objective: Atrophoderma of Pasini and Pierini (APP) is an uncommon cutaneous disorder, with no known effective treatment, manifested by hyperpigmented patches that appear to be depressed compared with surrounding skin. This study investigated the effectiveness of the Q-switched alexandrite laser on a patient with extensive APP, and evaluated histopathologic and ultrastructural changes.

    Study Design/materials And Methods: A man with stable APP underwent Q-switched alexandrite laser treatment to a patch on the trunk. Read More

    Disaccharide analysis of skin glycosaminoglycans in atrophoderma of Pasini and Pierini.
    Clin Exp Dermatol 2000 Jul;25(5):436-40
    Department of Dermatology, Gunma University School of Medicine, Maebashi, Japan.
    There are divergent opinions as to whether atrophoderma of Pasini and Pierini (APP) is a nosologic entity or a primary atrophic morphoea. In this study, we used high performance liquid chromatography to analyse the skin disaccharide contents of glycosaminoglycan (GAG) in two patients with APP and compared the results with those from a typical atrophic morphoea patient. Perilesional uninvolved skin was used as a control in each patient. Read More

    [The use of a silver staining method in the diagnosis of the late skin lesions in ixodid tick-borne borreliosis in man].
    Parazitologiia 1999 May-Jun;33(3):267-9
    The borreliosis etiology was verified in 60% cases of the morphea, 100% cases of the atrophoderma of Pasini-Pierini and 100% cases of anetoderma by means of IFA with Ip-21 antigen (B. afzelii) and silver staining after Levadity. Borreliae were located near the capillaries, muscular and areolar tissue fibers of the derm and near the granulated cells of epidermis. Read More

    Scleroderma overlap syndromes.
    Adv Exp Med Biol 1999 ;455:85-92
    Department of Dermatology, Warsaw School of Medicine, Poland.
    The most common scleroderma overlap syndromes are mixed connective tissue disease (MCTD), scleromyositis and synthetase syndrome. There is controversy concerning MCTD as a separate entity due to heterogeneous clinical manifestations, not infrequent transformation into definite CTD and various classification criteria. Our study of 94 adult patients and 20 children, classified according to the criteria of Alarcon-Segovia, and especially a 5, 9-year follow-up showed transformation into SLE or SSc in over 20% of patients, less frequently than reported by others, whereas over half of the cases remained undifferentiated CTD. Read More

    Scleroderma-like disorders.
    Semin Cutan Med Surg 1998 Mar;17(1):65-76
    Department of Dermatology, Warsaw School of Medicine, Poland.
    Scleroderma-like disorders are widely disparate conditions mimicking either systemic sclerosis or cutaneous localized scleroderma, not infrequently displaying features of both. Some are exclusively sclerotic, some scleroatrophic with prevailing sclerosis or atrophies. The recognition of scleroderma-like disorders is of practical importance because by establishing the cause of the disease, it is possible to introduce an effective therapy, as in scleredema Buschke or scleredema diabeticorum, sclerodermiform porphyria, Borrelia burgdorferi-induced sclerodermiform acrodermatitis atrophicans, sclerodermiform phenylketonuria, drug-induced conditions, and so on. Read More

    1 OF 2