22,261 results match your criteria Atrial Septal Defect

Non-surgical treatment of Lutembacher syndrome: combined percutaneous transcatheter therapy.

BMJ Case Rep 2022 May 18;15(5). Epub 2022 May 18.

Periodontology, AB Shetty Memorial Institute of Dental Sciences, Mangalore, Karnataka, India.

A woman in her 30s presented with progressive worsening of dyspnoea for 6 months. On evaluation, she was diagnosed with severe rheumatic mitral stenosis (mitral valve area of 0.6 cm) and a large ostium secundum atrial septal defect (21 mm) with a left to right shunt and severe pulmonary artery hypertension. Read More

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Concomitant Redo Transcatheter Aortic Valve Replacement and Valve-in-Mitral Annular Calcification.

JACC Case Rep 2022 May 4;4(9):512-515. Epub 2022 May 4.

Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA.

Contemporary challenges in structural heart intervention include redo transcatheter aortic valve replacement and transcatheter mitral valve replacement in severe mitral annular calcification. We report a case of concomitant redo transcatheter aortic valve replacement and transcatheter mitral valve replacement in mitral annular calcification in a patient with radiation heart disease. (). Read More

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Epidemiology of Congenital Heart Disease in Jinan, China From 2005 to 2020: A Time Trend Analysis.

Front Cardiovasc Med 2022 27;9:815137. Epub 2022 Apr 27.

Department of Women Healthcare, Jinan Maternity and Child Care Hospital Affiliated to Shandong First Medical University, Jinan, China.

Background: Although congenital heart defect (CHD) was the dominating birth defect, the time trend analysis of CHD was largely unknown. In our study, the time trend analysis of CHD from 2005 to 2020 in Jinan was conducted, aimed to reveal the epidemiological characteristics in a city and provided the data basis for the government to make a policy intervention.

Methods: A multi-institutional and retrospective review of CHD for all births from January 1, 2005 to December 31, 2020 was performed. Read More

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Long-Term Survival of Adult Patients With Atrial Septal Defect With Regards to Defect Closure and Pulmonary Hypertension.

Front Cardiovasc Med 2022 28;9:867012. Epub 2022 Apr 28.

Department of Cardiac Surgery, Na Homolce Hospital, Prague, Czechia.

Background: Atrial septal defect (ASD) is the most common congenital heart disease (CHD) in adults and pulmonary hypertension (PH) is an established risk factor. A decision whether to perform ASD closure, especially in elderly patients with PH, is a complex dilemma. The aim of our study was to compare long-term survival in patients with closed and open ASD. Read More

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Deciphering complex rearrangements at the breakpoint of an apparently balanced reciprocal translocation t(4:18)(q31;q11.2)dn and at a cryptic deletion: Further evidence of TLL1 as a causative gene for atrial septal defect.

Am J Med Genet A 2022 May 14. Epub 2022 May 14.

Center for Medical Genetics, Keio University School of Medicine, Tokyo, Japan.

When a de novo balanced reciprocal translocation is identified in patients with multiple congenital abnormalities, attempts are often made to infer the relationship between the phenotype of the patient and genes in the proximity of the breakpoint. Here, we report a patient with intellectual disability, atrial septal defect, syndactyly, and cleft lip and palate who had an "apparently balanced" de novo reciprocal translocation t(4:18)(q31;q11.2) as well as a 7-Mb cryptic deletion spanning the HOXD cluster on chromosome 2q31 that was unrelated to the reciprocal translocation. Read More

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Intracardiac Echocardiogram: Feasibility, Efficacy, and Safety for Guidance of Transcatheter Multiple Atrial Septal Defects Closure.

J Clin Med 2022 Apr 24;11(9). Epub 2022 Apr 24.

Division of Pediatric Cardiology, Department of Pediatrics, Congenital Heart Disease Center, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul 03722, Korea.

We aimed to determine the feasibility, efficacy, success, and safety of intracardiac echocardiography (ICE) in transcatheter multiple atrial septal defect (ASD) closure. Of 185 patients with multiple ASDs who underwent transcatheter closure, 140 (76%) patients who weighed <30kg with a narrow distance between defects or in whom single device closure was anticipated were guided by ICE and 45 patients were guided by three-dimensional (3D) transesophageal echocardiography (TEE) with or without ICE. Patients in the ICE group were relatively younger and weighed less than those in the 3D TEE group ( < 0. Read More

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Intraoperative Collateral Drainage Evaluation Before Superior Caval Interruption in Partial Anomalous Pulmonary Venous Connection Repair.

Innovations (Phila) 2022 May 13:15569845221097790. Epub 2022 May 13.

Cardiovascular Surgery, 16493Hospital Clínic, University of Barcelona, Spain.

A superior sinus venosus atrial septal defect and partial anomalous pulmonary venous connection was corrected by a minimally invasive approach by permanently ligating the superior vena cava and a single pericardial patch for rerouting the flow through the enlarged interatrial communication. The patient had persistency of the left superior vena cava draining in the coronary sinus but no innominate vein. This anatomy poses a risk of developing right-sided superior vena cava syndrome. Read More

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Multimodal Imaging for Total Anomalous Systemic Venous Drainage Diagnosis and Preoperative Planning: A Case Report and Literature Review.

Front Cardiovasc Med 2022 25;9:786278. Epub 2022 Apr 25.

Department of Cardiovascular Function, People's Hospital of China Medical University, People's Hospital of Liaoning Province, Shenyang, China.

Total anomalous systemic venous drainage (TASVD) is a rare congenital heart malformation. Here, we report a case of a 40-year-old male patient who had a total anomalous systemic venous drainage. It was diagnosed as the TASVD for the first time through multimodal imaging combined Transthoracic (TTE), transesophageal (TEE) and three-dimensional (3D-TTE) echocardiography, contrast echocardiography and computed tomography angiography (CTA). Read More

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Impact of dose reducing software on patient and staff temple dose during fluoroscopically guided pacemaker insertion, closure devices implantation and coronary angiography procedures.

Phys Eng Sci Med 2022 May 9. Epub 2022 May 9.

School of Chemistry and Physics, Faulty of Science, Queensland University of Technology, 2 George Street, Brisbane, QLD, 4000, Australia.

The aim of this study is to investigate the effectiveness of dose reducing software (ClarityIQ) on patient and staff dose during fluoroscopically guided cardiac procedures. Dose measurements were collected in a room without dose reducing software (n = 157) and compared with similar procedures performed in two rooms with the software (n = 1141). Procedures included diagnostic coronary angiography, percutaneous coronary intervention, deployment of cardiac closure devices (for occlusion of atrial septal defect, patent foramen ovale, and atrial appendage) and insertion of permanent pacemakers. Read More

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Clinical Status and Outcome of Isolated Right Ventricular Hypoplasia: A Systematic Review and Pooled Analysis of Case Reports.

Front Pediatr 2022 21;10:794053. Epub 2022 Apr 21.

Department of Pediatrics, International University of Health and Welfare, Tokyo, Japan.

Background: Isolated right ventricular hypoplasia (IRVH), not associated with severe pulmonary or tricuspid valve malformation, is a rare congenital myocardial disease. This study aims to evaluate the clinical status and outcome of IRVH.

Methods: A systematic search of keywords on IRVH was conducted. Read More

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Complications of trans-catheter closure of atrial septal defects.

Indian J Thorac Cardiovasc Surg 2022 May 21;38(3):262-267. Epub 2022 Mar 21.

The Department of Cardiology, The Christian Medical College, Vellore, Tamil Nadu 632004 India.

Trans-catheter device closure of atrial septal defects (ASD) is considered to be safe with minimal complications. But, there are certain complications that arise after these device closures which might require urgent or late surgical intervention. We have retrospectively analysed our experience. Read More

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Post-infarction ventricular septal defect with cardiogenic shock: peripheral veno-arterial extracorporeal membrane oxygenator as a bridge to surgery.

Indian J Thorac Cardiovasc Surg 2022 May 5;38(3):317-320. Epub 2022 Jan 5.

Department of Cardiovascular Surgery, Mayo Clinic College of Medicine, First Street SW, Rochester, MN 55905 USA.

We present a patient with post-infarction posterior ventricular septal defect complicated by cardiogenic shock who was transferred after percutaneous coronary revascularization. A peripheral venoarterial extracorporeal membrane oxygenator was placed as a bridge to definite treatment to stabilize his condition. Patch closure of the ventricular septal defect and tricuspid valve replacement were performed successfully with right atrial approach 3 days after the extracorporeal membrane oxygenation (ECMO) placement and 11 days after the myocardial infarction. Read More

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An Atrial Septal Ridge Diagnosed by Transesophageal Echocardiography.

Methodist Debakey Cardiovasc J 2022 18;18(1):14-16. Epub 2022 Apr 18.

Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, US.

A left atrial ridge is an anomaly of irregular fusion between the septum primum and septum secundum.1 Aberrant fusion of the septa results in thickened and fibrotic tissue along the region of the fossa ovalis that will occasionally protrude into the left atrium.2 The presence of a left atrial ridge has multiple clinical implications due to its close proximity to the fossa ovalis. Read More

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Further clarification on the variants of double-outlet right atrium.

Ann Pediatr Cardiol 2021 Oct-Dec;14(4):490-495. Epub 2022 Mar 25.

Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, United Kingdom.

Uniatrial but biventricular atrioventricular connection is a rare congenital cardiac abnormality where the left atria-ventricular connection is absent and the right atrio-ventricular connection straddles the crest of the muscular ventricular septum. This anomaly has been referred to as double outlet right atrium and the atrio-ventricular valve as a common atrioventricular valve in the past. In the absence of a primary atrial septal defect, the atrio-ventricular junction is not a common junction and the valve cannot hence be described as a common trio-ventricular valve. Read More

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Eisenmenger Syndrome Among Children with Unrepaired Congenital Heart Defects in Yunnan, China.

Pediatr Cardiol 2022 May 6. Epub 2022 May 6.

Susan and Henry Samueli College of Health Sciences, Program in Public Health, University of California Irvine, Irvine, CA, 92697, USA.

Eisenmenger syndrome is a life-threatening complication of congenital heart defects (CHD). Since Eisenmenger syndrome among children of repaired CHD is rare, very few studies have had the necessary data to investigate its distribution in children. The current study used data collected in rural China to investigate the prevalence of Eisenmenger syndrome in children with unrepaired CHD. Read More

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Maternal nicotine exposure induces congenital heart defects in the offspring of mice.

J Cell Mol Med 2022 May 6. Epub 2022 May 6.

Department of Physiology and Pharmacology, London, Ontario, Canada.

Maternal cigarette smoking is a risk factor for congenital heart defects (CHDs). Nicotine replacement therapies are often offered to pregnant women following failed attempts of smoking cessation. However, the impact of nicotine on embryonic heart development is not well understood. Read More

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variant with the novel phenotype of mixed‑type total anomalous pulmonary venous return in Holt‑Oram Syndrome and variable intrafamilial heart defects.

Mol Med Rep 2022 Jun 6;25(6). Epub 2022 May 6.

Pediatric Genomics Discovery Program, Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06504, USA.

Variants in T‑box transcription factor 5 () can result in a wide phenotypic spectrum, specifically in the heart and the limbs. has been implicated in causing non‑syndromic cardiac defects and Holt‑Oram syndrome (HOS). The present study investigated the underlying molecular etiology of a family with heterogeneous heart defects. Read More

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Endothelialization and Inflammatory Reactions After Intracardiac Device Implantation.

Adv Exp Med Biol 2022 May 5. Epub 2022 May 5.

Department of Internal Medicine II, Division of Cardiology, Paracelsus Medical University of Salzburg, Salzburg, Austria.

Background: Due to the advances in catheter-based interventional techniques, a wide range of heart diseases can now be treated with a purely interventional approach. Little is yet known regarding biological effects at the intracardiac implantation site or the effects on endothelialization and vascular inflammation in an in vivo environment. Detailed knowledge of ongoing vascular response, the process of endothelialization, and possible systemic inflammatory reactions after implantation is crucial for the clinical routine, since implants usually remain in the body for a lifetime. Read More

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Short-term results of percutaneous closure of a patent foramen ovale guided by transoesophageal echocardiography in patients with cryptogenic stroke: a retrospective study.

J Cardiothorac Surg 2022 May 3;17(1):96. Epub 2022 May 3.

Department of Cardiovascular Surgery, The Second Affiliated Hospital of Hainan Medical University, 48th of Bai Shui Tang Road, Haikou, Hainan, 570311, People's Republic of China.

Background: A patent foramen ovale (PFO) is a risk factor for cryptogenic stroke (CS), and interventional therapy for PFO can reduce the recurrence rate of CS. However, interventional therapies are primarily guided by X-ray imaging, and data on regular post-surgical follow-up with the transthoracic ultrasound foaming test (UFT) are rare. Thus, this study aimed to assess the short-term (12 months) results of PFO occlusion guided by transoesophageal echocardiography (TEE) and the results of regular UFTs. Read More

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Comparison of the efficacy and safety of sedation protocols with the use of dexmedetomidine-remifentanil and propofol-remifentanil during percutaneous closure of atrial septal defects: a randomized clinical trial.

J Cardiothorac Surg 2022 May 3;17(1):100. Epub 2022 May 3.

Department of Cardiovascular Surgery, Fujian Medical University Union Hospital, Fuzhou, 350001, Fujian Province, People's Republic of China.

Background: The study was aimed to compare the efficacy and safety of different sedation protocols of dexmedetomidine-remifentanil and propofol-remifentanil for percutaneous closure of atrial septal defects (ASD) under transthoracic echocardiography (TTE) guidance.

Material And Methods: From March 2020 to January 2021, of 114 patients screened, 59 ASD patients scheduled for percutaneous closure under TTE guidance were randomly allocated into the dexmedetomidine-remifentanil (D-R) group (n = 29) and the propofol-remifentanil (P-R) group (n = 30). The incidence of hemodynamic and respiratory adverse events, arterial blood gas analysis, induction and recovery time, pain score, infusion rate of remifentanil, satisfaction of the surgeon and patient, additional sedatives were collected for analysis and comparison. Read More

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Mermaid syndrome: A case report in Somalia.

Ann Med Surg (Lond) 2022 Apr 29;76:103533. Epub 2022 Mar 29.

Department of Pediatric, Mogadishu Somalia Turkish Training and Research Hospital, Somalia.

Introduction: and Importance: Sirenomelia, which called sirenomelia sequences, is a very rare congenital malformation. It is characterized by complete or incomplete fused lower extremities, renal agenesis, oligohydramnios, absent urinary tract and external genitalia, single umbilical arteries, imperforate anus, etc.We are reporting a case of mermaid syndrome, a twin pregnancy in which one was healthy and the other was identified to have characteristic features of sirenomelia at the time of examination. Read More

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A case of ventricular noncompaction associated with heterotaxy and atrioventricular block diagnosed at 15 weeks of gestation using superb microvascular imaging.

J Obstet Gynaecol Res 2022 May 1. Epub 2022 May 1.

Department of Obstetrics and Gynecology, School of Medicine, Kurume University, Kurume, Japan.

We present a case of fetal atrioventricular block, heterotaxy, and ventricular noncompaction observed longitudinally from the first to early second trimesters using B-mode and Doppler imaging, including superb microvascular imaging. At 12 weeks of gestation, the atrial and ventricular rates were 133 and 67 beats/min, respectively, and dextrocardia was noted. At 15 weeks of gestation, detailed sonography revealed ventricular septal defect, interruption of the inferior vena cava, dilated azygos vein, and double-outlet right ventricle. Read More

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[Risk factors for syncope in children with severe idiopathic pulmonary arterial hypertension].

Zhonghua Er Ke Za Zhi 2022 May;60(5):442-446

Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing 100029, China.

To explore the risk factors for syncope in children with severe idiopathic pulmonary arterial hypertension (IPAH). Forty-four patients (age<18 years) with IPAH admitted to the Department of Pediatric Cardiology, Beijing Anzhen Hospital between May 2011 and October 2021 were retrospectively included. Patients were devided into syncope group and non-syncope group. Read More

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Bioinformatics Analysis Reveals Hub Genes That May Reduce Inflammation and Complications After Cardiopulmonary Bypass.

Heart Surg Forum 2022 Mar 24;25(2):E243-E252. Epub 2022 Mar 24.

Department of Cardiac Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.

Cardiopulmonary bypass (CPB), though indispensable in many cardiac surgery procedures, has several undesirable consequences. The aim of this study was to identify potential genes that may reduce the inflammatory response and complications after CPB. The GSE132176 dataset was selected from the Gene Expression Omnibus (GEO) database and included 10 patients with tetralogy of Fallot and 10 patients with an atrial septal defect who underwent CPB surgery. Read More

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Anomalous Connection of the Left Pulmonary Vein to the Coronary Sinus with Intact Atrial Septum in a Young Woman.

Heart Surg Forum 2022 Mar 29;25(2):E256-E258. Epub 2022 Mar 29.

Department of Cardiovascular Surgery, Weifang People's Hospital, Weifang, China.

Background: Left-sided partial anomalous pulmonary venous connection (PAPVC) is a rare congenital abnormal cardiac defect. An intact atrial septum is more uncommon. As we know, a connection of the left pulmonary vein (LPV) to the coronary sinus (CS) with an intact atrial septum has not been previously reported. Read More

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Perioperative Use of Pituitrin after Cardiac Defect Repair in Adult Patients with Severe Pulmonary Hypertension.

Heart Surg Forum 2022 Apr 21;25(2):E277-E283. Epub 2022 Apr 21.

Adult Cardiac Surgery Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Background: Vasopressin can constrict peripheral arteries without constricting the pulmonary artery. Theoretically, vasopressin is suitable for the perioperative treatment of pulmonary hypertension. Few studies have investigated the use of pituitrin (a substitute for vasopressin) after cardiac defect repair surgery. Read More

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Outcomes After Transcatheter Closure of Atrial Septal Defect Without Using a Balloon-Sizing Technique: A Randomized Controlled Comparison with Closures Using a Balloon-Sizing Technique.

Heart Surg Forum 2022 Apr 22;25(2):E288-E293. Epub 2022 Apr 22.

Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Background: The transcatheter closure of atrial septal defect could be completed without the balloon-sizing technique, so we evaluated long-term outcomes compared with closure using balloon sizing, which was the conventional method. Even without using the balloon-sizing technique, transcatheter closure of atrial septal defect might be safe and effective.

Methods: We included 124 patients with isolated atrial septal defects who underwent device closure without balloon sizing between 2012 and 2016, and we further included 257 patients as a control group. Read More

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Late bacterial endocarditis after percutaneous atrial septal defect closure.

Cardiol Young 2022 Apr 28:1-3. Epub 2022 Apr 28.

Department of Pediatric Cardiovascular Surgery, Saitama Children's Medical Center, Saitama330-8777, Japan.

Percutaneous atrial septal defect closure is widely used as an alternative to surgical repair in many hospitals. Infective endocarditis related to occluding devices is commonly known, but following that atrial septal defect closure with a device in a child is rare. This report describes an 11-year-old girl who developed late-stage bacterial endocarditis following incomplete endothelialisation after a percutaneous procedure. Read More

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