21,387 results match your criteria Atrial Septal Defect


Mending hearts: A further strategy to improve cardiac donors availability.

J Card Surg 2021 May 12. Epub 2021 May 12.

Heart Transplantation Unit, Cardio-Thoraco-Vascular Sciences and Public Health Department, University Padova Hospital, Padova, Italy.

Patients listed for heart transplantation are increasing annually worldwide, but the limited number of available donor hearts restricts this treatment to a small fraction of potential recipients. Attempts have, therefore, been made to expand the donor pool by recruiting donors who may not satisfy the standard criteria for organ donation. We reviewed our early experience by using three donor hearts which were successfully transplanted either after correction or not of pre-existing defects (Case #1: Coronary fistula; Case #2: Takayasu syndrome; Case #3: Percutaneously repaired atrial septal defect), demonstrating that structural cardiac abnormalities might not always be an absolute contraindication to donation candidacy. Read More

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Massive congenital immature teratoma of the lateral ventricle in a 33-day infant comorbidity with atrial septal defect.

Childs Nerv Syst 2021 May 11. Epub 2021 May 11.

Pediatric Neurosurgery, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, 200092, China.

Congenital teratomas are extremely rare and mainly midline tumors arising in the pineal regions in childhood brain tumors which are rarer cases occur in the lateral ventricle. Atrial septal defect (ASD) is detected in approximately 0.15% of newborns. Read More

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Venous drainage for minithoracotomy approach in an adult with interrupted inferior vena cava.

Asian Cardiovasc Thorac Ann 2021 May 11:2184923211017096. Epub 2021 May 11.

Department of Cardiovascular Surgery, Akashi Medical Center, Akashi, Japan.

For atrial septal defect closure via right minithoracotomy in an adult patient with infra-hepatic interruption of the inferior vena cava with azygos connection, an alternative venous cannulation strategy was applied. In addition to bicaval cannulations to the femoral vein and the internal jugular vein, a 20 Fr straight cannula draining the hepatic vein was added to the proximal IVC through the right atrium wall via a working port. A bloodless operative field in the right atrium was afforded with bicaval encircling. Read More

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Superior Vena Cava Stenosis Manifesting with Brain Abscess 2 Decades after Atrial Septal Defect Repair.

Radiol Cardiothorac Imaging 2021 Apr 8;3(2):e200561. Epub 2021 Apr 8.

Department of Radiology (A.C.F., M.L., J.M.L.) and Division of Cardiology, Department of Medicine (J.M.L.), Montefiore Medical Center, 111 E 210th St, Bronx, NY 10467; Department of Radiology, New York University, New York, NY (A.S.); and Division of Pediatric Cardiology, Children's Hospital at Montefiore, Bronx, NY (N.J.S., N.F.C.).

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Therapy of supraventricular and ventricular arrhythmias in adults with congenital heart disease-narrative review.

Cardiovasc Diagn Ther 2021 Apr;11(2):550-562

Department of Cardiology II - Electrophysiology, University Hospital Muenster, Cardiology, Muenster, Germany.

Arrhythmias are among the most common late complications in adults with congenital heart disease (ACHD) and a frequent reason for hospital admission. Both, supraventricular and ventricular arrhythmias, not only cause debilitating symptoms, but may be life-threatening by increasing risk of stroke, causing or worsening heart failure and being associated with sudden death. Substrate and risk for arrhythmia differs widely between congenital defects with specific arrhythmias being much more common in some patients than others. Read More

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German Heart Centre Munich-45 years of surgery in adults with congenital heart defects: from primary corrections of septal defects and coarctation to complex reoperations.

Cardiovasc Diagn Ther 2021 Apr;11(2):492-502

Department of Congenital and Paediatric Heart Surgery, German Heart Centre Munich, Technische Universität München, Munich, Germany.

Background: Our historical overview in the form of a cohort study aimed to describe the changes in the cardiac operations in adults with congenital heart disease (ACHD), over 45 years in the German Heart Centre in Munich.

Methods: The study population comprised all consecutive patients aged 18 or more, who underwent surgery for congenital heart disease (CHD) at the German Heart Centre Munich, between 1974 and 2018. Operations were coded according to the Adult Congenital Heart Surgery (ACHS) score. Read More

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Intracardiac relation of extrahepatic persistent right umbilical vein.

Indian J Thorac Cardiovasc Surg 2021 May 18;37(3):354-356. Epub 2020 Nov 18.

Department of Cardiovascular and Thoracic Surgery, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Medical College Campus, Thiruvananthapuram, Kerala 695011 India.

Persistent extrahepatic right umbilical vein without ductus venosus is a rare anomaly of systemic venous drainage and is reported to be associated with cardiac anomalies. We report the case of an 8-year-old boy diagnosed to have an ostium secundum atrial septal defect, in whom an abnormal vascular channel and its opening in the right atrium in close relationship to the inferior vena cava and coronary sinus opening was identified at operation. Post-operative evaluation of this vascular channel was diagnosed to be an extrahepatic persistent right umbilical vein. Read More

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Atrial septal defect closure: rethinking device vs surgery.

Indian J Thorac Cardiovasc Surg 2021 May 10;37(3):255-256. Epub 2021 Apr 10.

Department of CTVS, Naryana Multispeciality Hospital, Jaipur, Rajasthan India.

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Biodegradable polymeric occluder for closure of atrial septal defect with interventional treatment of cardiovascular disease.

Biomaterials 2021 Apr 26;274:120851. Epub 2021 Apr 26.

State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai, 200438, China. Electronic address:

The next-generation closure device for interventional treatment of congenital heart disease is regarded to be biodegradable, yet the corresponding biomaterial technique is still challenging. Herein, we report the first fully biodegradable atrial septal defect (ASD) occluder finally coming into clinical use, which is made of biodegradable poly(l-lactic acid) (PLLA). We characterized the physico-chemical properties of PLLA fibers as well as the raw polymer and the operability of the as-fabricated occluders. Read More

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Neurocognitive disorders amongst patients with congenital heart disease undergoing procedures in childhood.

Int J Cardiol 2021 May 6. Epub 2021 May 6.

McGill Adult Unit for Congenital Heart Disease Excellence, McGill University, Montreal, QC, Canada. Electronic address:

Background: Amongst children with congenital heart disease (CHD), earlier age of repair improves cardiovascular outcomes. The effects of early intervention on neurodevelopment remains unclear. We assessed the association between early life repair, cardiopulmonary bypass (CPB) and the incidence of neurocognitive disorders (NCD) amongst CHD patients. Read More

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Recent developments in next-generation occlusion devices.

Acta Biomater 2021 May 5. Epub 2021 May 5.

Center for Composite Materials and Structures, Harbin Institute of Technology (HIT), P.O. Box 3011, No. 2 Yikuang Street, Harbin 150080, People's Republic of China. Electronic address:

Transcatheter closure has been widely accepted as a highly effective way to treat abnormal blood flows and/or embolization of thrombus in the heart. It allows the closure of four types of congenital heart defects (CHDs) and stroke-associated left atrial appendage (LAA). The four types of CHDs include atrial septal defect (ASD), patent foramen ovale (PFO), patent ductus arteriosus (PDA), and ventricular septal defect (VSD). Read More

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Aortopulmonary collateral arteries in non-cyanotic congenital heart disease.

Ann Thorac Surg 2021 May 4. Epub 2021 May 4.

Department of Pediatric Intensive Care Unit, Pediatric Cardiac Center, Chinese Academy of Medical Sciences, Fuwai Hospital, Beijing, China; Department of Pediatric Intensive Care Unit, Pediatric Cardiac Center, Fuwai Yunnan Cardiovascular Hospital, Yunnan, China. Electronic address:

Development of major aortopulmonary collateral arteries (MAPCAs) are strongly associated with cyanotic congenital heart disease. However, MAPCAs have rarely been reported in non-cyanotic congenital heart disease. We report on a rare case of a newborn originally diagnosed with an atrial septal defect, a ventricular septal defect, and pulmonary arterial hypertension, who underwent complete repair. Read More

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Migraine-like headaches associated with nickel allergy requiring removal of atrial septal defect closure device.

Indian J Thorac Cardiovasc Surg 2021 May 1;37(3):299-302. Epub 2021 Mar 1.

Department of Cardiothoracic Surgery, Monash Medical Centre, Level 3, 246 Clayton Road, Clayton, Victoria 3168 Australia.

There is a deficit of literature regarding the association between nickel allergy-induced symptoms and implanted devices. This report describes a case of nickel allergy causing debilitating migraine-like symptoms, failing to resolve with medical therapy, requiring surgical removal of the device and repair of the defect. Read More

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Atrial Septal Defect Closure via Left Subclavian Vein Approach in a Patient With Absent Inferior Vena Cava.

World J Pediatr Congenit Heart Surg 2021 May 6:2150135120983807. Epub 2021 May 6.

Department of Cardiology, Sendai Kousei Hospital, Aoba, Sendai, Miyagi, Japan.

Without the femoral venous approach, transcatheter closure of an atrial septal defect is challenging. We performed percutaneous closure via the left subclavian vein in a patient with absence of the inferior vena cava with azygos continuation. Considering that inferior vena cava anomalies are not extremely rare among those with congenital heart disease, the left subclavian vein approach can be an alternative to the femoral approach. Read More

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Patient-specific iPSC-derived cardiomyocytes reveal abnormal regulation of FGF16 in a familial atrial septal defect.

Cardiovasc Res 2021 May 6. Epub 2021 May 6.

Department of Cardiovascular Surgery of the First Affiliated Hospital & Institute for Cardiovascular Science, Collaborative Innovation Center of Hematology, State Key Laboratory of Radiation Medicine and Protection, Medical College, Soochow University, Suzhou, 215000, China.

Aims: Congenital heart disease (CHD) frequently occurs in newborns due to abnormal formation of the heart or major blood vessels. Mutations in the GATA4 gene, which encodes GATA binding protein 4, are responsible for atrial septal defect (ASD), a common CHD. This study aims to gain insights into the molecular mechanisms of CHD using human induced pluripotent stem cells (iPSCs) from a family cohort with ASD. Read More

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Totally anomalous pulmonary venous connection with intact atrial septum.

J Card Surg 2021 May 5. Epub 2021 May 5.

Department of Cardiothoracic and Vascular Surgery, All India Institute of Medical Sciences, New Delhi, India.

Background: Total anomalous pulmonary venous connection with intact interatrial septum is extremely rare.

Aims: In these patients, a right to left shunt through a ventricular septal defect or a patent ductus arteriosus is mandatory to maintain the systemic circulation. Mechanical or physiological restriction of shunting through these pathways results in rapid clinical deterioration. Read More

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Platypnoea-orthodeoxia syndrome in COVID-19.

BMJ Case Rep 2021 May 5;14(5). Epub 2021 May 5.

Department of Medicine, AIIMS, New Delhi, India.

Platypnoea-orthodeoxia syndrome (POS) is a rare entity characterised by respiratory distress and/or hypoxia developing in the sitting/upright posture, which is relieved in the supine posture. It is caused by cardiac, pulmonary and non-cardiopulmonary diseases. COVID-19 can have varying respiratory manifestations including acute respiratory distress syndrome (ARDS) and sequelae-like pulmonary fibrosis. Read More

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The Incidence of Congenital Heart Defects in Offspring Among Women With Diabetes in Saudi Arabia.

Cureus 2021 Mar 31;13(3):e14225. Epub 2021 Mar 31.

Biostatistics, King Saud bin Abdulaziz University for Health Sciences, Riyadh, SAU.

Background: The risk of congenital anomalies is increased in infants of diabetic mothers (IDM). The most frequent cardiac anomalies in IDMs include ventricular septal defect, transposition of great arteries, and aortic stenosis.

Objective: Estimating the incidence of infants with congenital heart defects (CHD) whose mothers have diabetes in Saudi Arabia at a tertiary hospital in the National Guard Health Affairs (NGHA) system. Read More

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First Harvest of Pediatric and Congenital Heart Surgery Multicenter Database in Turkey: Novel Application of Real-Time Online Reporting.

World J Pediatr Congenit Heart Surg 2021 May;12(3):377-386

Acibadem Mehmet Ali Aydinlar University, School of Medicine, Atakent Hospital, Istanbul, Turkey.

Objectives: A new congenital heart surgery database (CKCV) with real-time online reporting function was recently developed in Turkey. All standard international parameters were used, but Aristotle Comprehensive Complexity score was modified. In this study, the first analysis of the CKCV Database is reported. Read More

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Transaxillary Approach for Surgical Repair of Simple Congenital Cardiac Lesions: Pitfalls, and Complications.

World J Pediatr Congenit Heart Surg 2021 May;12(3):337-343

Department of Pediatric Cardiology, 29286Amrita Institute of Medical Sciences and Research Centre, Edappally, Kochi, India.

Background: In the treatment of simple congenital cardiac lesions, percutaneous and cosmetic surgical approaches have steadily gained prominence. Surgically, right vertical axillary approach is sparsely used despite superior cosmesis and less pain and blood product usage. Knowledge of potential pitfalls could lead to its more widespread acceptance. Read More

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Surgical treatment of partial anomalous pulmonary venous connection misdiagnosed as atrial septal defect underwent transcatheter occlusion: A case report.

Clin Case Rep 2021 Apr 11;9(4):2345-2349. Epub 2021 Mar 11.

Department of Cardiovascular Surgery State Key Laboratory of Cardiovascular Disease Fuwai Hospital National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.

This case highlights the importance of coordinating with cardiopediatricians or congenitalists in the evaluation and treatment of ASD. Read More

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Defibrillation Safety Margin Testing in Patients With Congenital Heart Disease: Results From the NCDR.

JACC Clin Electrophysiol 2021 Apr 22. Epub 2021 Apr 22.

Section of Cardiac Electrophysiology, Division of Cardiology, University of California-San Diego, La Jolla, California, USA.

Objectives: This study analyzed the predictors of defibrillation safety margin (DSM) testing at the time of implantable cardioverter-defibrillator (ICD) insertion and factors associated with inadequate DSM in patients with congenital heart disease (CHD).

Background: There are few data about the prevalence and safety of DSM testing in those with CHD.

Methods: A retrospective analysis was performed of all patients with atrial or ventricular septal defect, tetralogy of Fallot, transposition of the great vessels, Ebstein anomaly, or common ventricle undergoing a transvenous ICD procedure in the National Cardiovascular Data Registry (NCDR) ICD Registry from April 2010 to March 2016, and DSM testing was assessed. Read More

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Application and effects of an early childhood education machine on analgesia and sedation in children after cardiothoracic surgery.

J Cardiothorac Surg 2021 May 1;16(1):118. Epub 2021 May 1.

Department of Cardiac Surgery, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, China.

Objective: To study the effect of an early childhood education machine on sedation and analgesia in children after cardiothoracic surgery.

Methods: A prospective randomized controlled study was conducted in a provincial hospital in China. Fifty-two patients (aged from 1 to 5 years) underwent cardiothoracic surgery (including: ventricular septal defect, patent ductus arteriosus, atrial septal defect, pulmonary stenosis, pulmonary sequestration and congenital cystic adenomatoid lung malformation) were divided into the study group (n = 26) and the control group (n = 26). Read More

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Lung cancer with partial anomalous pulmonary venous connection in a different lobe: a case report.

J Cardiothorac Surg 2021 May 1;16(1):122. Epub 2021 May 1.

Department of General Thoracic Surgery, Nihonkai General Hospital, 30 Akiho-cho, Sakata, Yamagata, Japan.

Background: Anomalous pulmonary venous connection (APVC) is a congenital malformation in which the pulmonary veins connect to the systemic venous system but not to the left atrium. APVC can be classified as total or partial (PAPVC). PAPVC is rare among surgical patients with lung cancer, and most cases are detected incidentally during surgery. Read More

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Safety of perioperative period in robot-assisted atrial septal defect repair under hyperkalemic arrest.

JA Clin Rep 2021 May 1;7(1):41. Epub 2021 May 1.

Department of Cardiac Surgery, New Heart Watanabe Institute, Hamadayama 3-19-11, Suginami-ku, Tokyo, Japan.

Background: Various attempts have been made to meet patient desires, especially among younger and otherwise healthy individuals, for cosmetically satisfying incision with atrial septal defect (ASD) repair. One of procedures was a robotic-assisted totally endoscopic ASD repair via only two ports under hyperkalemic arrest without aortic cross-clamping. This study investigated perioperative management and safety for robotic-assisted total endoscopic ASD repair surgery under hyperkalemic arrest. Read More

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Novel Autosomal Recessive Splice-Altering Variant in Is Associated with Congenital Heart Disease.

Genes (Basel) 2021 Apr 21;12(5). Epub 2021 Apr 21.

Developmental Medicine Department, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Ministry of National Guard- Health Affairs (MNG-HA), Riyadh 11481, Saudi Arabia.

Congenital heart defects (CHDs) are the most common types of birth defects, and global incidence of CHDs is on the rise. Despite the prevalence of CHDs, the genetic determinants of the defects are still in the process of being identified. Herein, we report a consanguineous Saudi family with three CHD affected daughters. Read More

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Coarctation of the aorta with total anomalous pulmonary venous connection: a case report.

AME Case Rep 2021 25;5:11. Epub 2021 Apr 25.

Department of Cardiovascular Surgery, Kitasato University School of Medicine, Sagamihara, Japan.

Total anomalous pulmonary venous connection (TAPVC) and coarctation of the aorta (CoA) rarely occur together. In affected patients, blood is supplied to the lower body by saturated ductal flow. Preoperative echocardiography may not show an acceleration of flow at the isthmus (coarctation), and the oxygen saturation (SpO) at the feet may be satisfactory. Read More

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A Rare Case of Multiple Nevoid Hypertrichosis with Atrial Septal Defect.

Ann Dermatol 2020 Dec 11;32(6):531-533. Epub 2020 Nov 11.

Department of Dermatology, Busan Paik Hospital, College of Medicine, Inje University, Busan, Korea.

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December 2020

Correction of sinus venosus atrial septal defects with the 10 zig covered Cheatham-platinum stent - An international registry.

Catheter Cardiovasc Interv 2021 Apr 28. Epub 2021 Apr 28.

The Department of Pediatrics, The Smidt Heart Institute, Cedars Sinai Medical Center, Los Angeles, California, USA.

Background: Covered stent correction of sinus venosus ASDs (SVASD) is a relatively new technique. Challenges include anchoring a sufficiently long stent in a nonstenotic superior vena cava (SVC) and expanding the stent at the wider SVC-RA junction without obstructing the anomalous right upper pulmonary vein (RUPV). The 10-zig covered Cheatham-platinum (CCP) stent has the advantage of being available in lengths of 5-11 cm and dilatable to 34 mm in diameter. Read More

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Diagnosing Atrial Septal Defect from Electrocardiogram with Deep Learning.

Pediatr Cardiol 2021 Apr 27. Epub 2021 Apr 27.

Institute of Advanced BioMedical Engineering and Science, Tokyo Women's Medical University, Tokyo, 162-0054, Japan.

The heart murmur associated with atrial septal defects is often faint and can thus only be detected by chance. Although electrocardiogram examination can prompt diagnoses, identification of specific findings remains a major challenge. We demonstrate improved diagnostic accuracy realized by incorporating a proposed deep learning model, comprising a convolutional neural network (CNN) and long short-term memory (LSTM), with electrocardiograms. Read More

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