20,620 results match your criteria Atrial Septal Defect


Late complication of Amplatzer Duct Occluder: Erosion and Pseudoaneurysm.

Ann Thorac Surg 2020 May 31. Epub 2020 May 31.

Dept of Anaesthesia and Intensive Care, Narayana Institute of Cardiac Sciences, Bengaluru.

We are presenting a delayed complication of Amplatzer duct occluder (ADO) where the patient presented with increasing hemoptysis due to ADO eroding the vessel wall and forming a pseudoaneurysm which communicated with the left main bronchus. Though ADO is considered as the safest for catheter based patent ductus arteriosus closures, isolated complication as reported can occur. Just like atrial septal defect device closures, which were considered safe initially and found to be having an erosion incidence of 0. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2020.04.053DOI Listing

The Prevalence of Congenital Heart Diseases in Syndromic Children at King Khalid National Guard Hospital from 2005 to 2016.

Cureus 2020 Apr 29;12(4):e7891. Epub 2020 Apr 29.

Pediatric Cardiology, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.

Background Congenital heart diseases (CHDs) are abnormalities that present in the heart since birth and are one of the leading causes of infant mortality in the world. CHDs are more common among children with dysmorphic syndromes. The current study aims to estimate the prevalence of many CHDs in different dysmorphic syndromes. Read More

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http://dx.doi.org/10.7759/cureus.7891DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255536PMC

Survival, Morbidities, and Developmental Outcomes among Low Birth Weight Infants with Congenital Heart Defects.

Am J Perinatol 2020 Jun 2. Epub 2020 Jun 2.

Department of Pediatrics, Duke University Medical Center, Durham, North Carolina.

Objective:  Prematurity and low birth weight (LBW) are risk factors for increased morbidity and mortality in infants with congenital heart defects (CHDs). We sought to describe survival, inhospital morbidities, and 2-year neurodevelopmental follow-up in LBW infants with CHD.

Study Design:  We included infants with birth weight (BW) <2,500 g diagnosed with CHD (except isolated patent ductus arteriosus) admitted January 2013 to March 2016 to a single level-IV academic neonatal intensive care unit. Read More

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http://dx.doi.org/10.1055/s-0040-1712964DOI Listing

Interrupted aortic arch: A case report.

Indian J Radiol Imaging 2020 Jan-Mar;30(1):81-83. Epub 2020 Mar 30.

Department of Radiology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.

Interrupted aortic arch diagnosed in adult age is a rare entity, with only a few cases published in the literature. Most of them are classified as type A interrupted aortic arch and differential diagnosis is associated with severe chronic coarctation. We present a case of a 52-year-old woman accessed to the emergency department for chest and right upper limb pain that increased in the last days. Read More

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http://dx.doi.org/10.4103/ijri.IJRI_273_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240901PMC

Hemodynamics of an Iatrogenic Atrial Septal Defect (IASD) after MitraClip Implantation.

Eur J Clin Invest 2020 May 31:e13295. Epub 2020 May 31.

Innere Medizin III, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Kiel, Germany.

Background: The MitraClip procedure requires transseptal access of the left atrium with a 24 F guiding sheath. We evaluated invasively whether a MitraClip induced iatrogenic atrial septal defect (IASD) leads to development of a relevant interatrial shunt and right ventricular overload.

Methods: A total of 69 patients who underwent a MitraClip procedure due to a severe mitral valve regurgitation (MVR) were included in the observational, retrospective cohort study. Read More

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http://dx.doi.org/10.1111/eci.13295DOI Listing

Creating the BELgian COngenital heart disease database combining administrative and clinical data (BELCODAC): Rationale, design and methodology.

Int J Cardiol 2020 May 27. Epub 2020 May 27.

KU Leuven Department of Public Health and Primary Care, Academic Center for Nursing and Midwifery, KU Leuven - University of Leuven, Leuven, Belgium; Institute of Health and Care Sciences, University of Gothenburg, Gothenburg, Sweden; Department of Pediatrics and Child Health, University of Cape Town, Cape Town, South Africa. Electronic address:

Background: Congenital heart disease (CHD) entails a broad spectrum of malformations with various degrees of severity and prognosis. Consequently, new and specific healthcare needs are emerging, requiring responsive healthcare provision. Research on this matter is predominantly performed on population-based databases, to inform clinicians, researchers and policy-makers on health outcomes and economic burden of CHD. Read More

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http://dx.doi.org/10.1016/j.ijcard.2020.05.059DOI Listing

Elaborate evaluation of serial changes in electrocardiograms of atrial septal defects after transcatheter closure for a better understanding of the recovery process.

Heart Vessels 2020 May 29. Epub 2020 May 29.

Health Care Center, Fukuoka Dental College Hospital, Tamura 2-15-1, Sawaraku, Fukuoka, 814-0193, Japan.

Serial changes of electrocardiograms (ECG) could be used to assess their clinical features in atrial septal defects (ASD) after transcatheter closure together with other clinical parameters. We retrospectively studied 100 ASD patients who underwent transcatheter closure. Complications of persistent atrial fibrillation occurred in five ASD patients, and they were excluded. Read More

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http://dx.doi.org/10.1007/s00380-020-01632-xDOI Listing

Diagnosis of Ebstein Anomaly with Atrial Septal Defect and Persistent Left Superior Vena Cava Using Cardiac Magnetic Resonance Imaging.

J Cardiovasc Imaging 2020 May 27. Epub 2020 May 27.

Department of Radiology, Soonchunhyang University Hospital, Seoul, Korea.

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http://dx.doi.org/10.4250/jcvi.2019.0132DOI Listing

Unroofed coronary sinus atrial septal defect: 4D flow cardiovascular magnetic resonance vs. cardiac computed tomography.

Eur Heart J Cardiovasc Imaging 2020 May 27. Epub 2020 May 27.

European University of Madrid. Calle Tajo, s/n, 28670 Villaviciosa de Odón, Madrid.

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http://dx.doi.org/10.1093/ehjci/jeaa071DOI Listing

Determination of anomalous pulmonary venous return with high-pitch low-dose computed tomography in pediatric patients.

Folia Morphol (Warsz) 2020 May 27. Epub 2020 May 27.

Background: In this study, we aimed to image pulmonary venous return anomalies and associated cardiovascular and pulmonary abnormalities by high-pitch low-dose computed tomography (CT) in children.

Materials And Methods: Forty-one patients with total or partial anomalous pulmonary venous return anomalous between May 2012 and June 2019 were retrospectively reviewed. The anomalies were determined using high-pitch low-dose CT. Read More

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http://dx.doi.org/10.5603/FM.a2020.0054DOI Listing

Intubation precautions in a pediatric patient with severe COVID-19.

J Pediatr Surg Case Rep 2020 Jul 18;58:101495. Epub 2020 May 18.

Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, USA.

We present the case of a child diagnosed with COVID-19 soon after open-heart surgery who required an urgent second surgery. The patient suffered from severe COVID-19 disease. The utility of preoperative COVID-19 testing, determination of recovery by an array of inflammatory markers and perioperative management are described. Read More

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http://dx.doi.org/10.1016/j.epsc.2020.101495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7233244PMC

Reassessment of the location of the conduction system in atrioventricular septal defect using phase-contrast computed tomography.

Semin Thorac Cardiovasc Surg 2020 May 22. Epub 2020 May 22.

Division of Biomedical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.

The location of the atrioventricular conduction axis in the setting of atrioventricular septal defect has previously been shown by histology and intraoperative recordings. We have now re-assessed the arrangement using phase-contrast computed tomography, aiming to provide precise measurements so as to optimize future surgical repairs. We used the system based on an X-ray Talbot grating interferometer using the beamline BL20B2 in a SPring-8 synchrotron radiation facility available in Japan. Read More

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http://dx.doi.org/10.1053/j.semtcvs.2020.03.011DOI Listing

The heart's hidden flaw: A secundum atrial septal defect with inferior extension evades detection.

J Cardiovasc Comput Tomogr 2020 Apr 21. Epub 2020 Apr 21.

Tripler Army Medical Center, Department of Radiology, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jcct.2020.03.006DOI Listing

Identification of a 6-month-old baby with a combination of WAGR and Potocki-Shaffer contiguous deletion syndromes by SNP array testing.

Hereditas 2020 May 23;157(1):23. Epub 2020 May 23.

Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, 100191, China.

WAGR 11p13 deletion syndrome is associated with abnormalities including (W) ilms tumor, (A) niridia, (G) enitourinary abnormalities, and growth and mental (R) etardation (WAGR). Potocki-Schaffer syndrome is a contiguous gene syndrome associated with deletions in 11p11.2, principal features of which are multiple exostoses, parietal foramina development delay, mental retardation, and facial dysmorphism. Read More

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http://dx.doi.org/10.1186/s41065-020-00132-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245943PMC

A systematic review and meta-analyses of pregnancy and fetal outcomes in women with multiple sclerosis: a contribution from the IMI2 ConcePTION project.

J Neurol 2020 May 22. Epub 2020 May 22.

Population Health Research Institute, St George's, University of London, London, UK.

Neurologists managing women with Multiple Sclerosis (MS) need information about the safety of disease modifying drugs (DMDs) during pregnancy. However, this knowledge is limited. The present study aims to summarize previous studies by performing a systematic review and meta-analyses. Read More

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http://dx.doi.org/10.1007/s00415-020-09913-1DOI Listing

Current practice in atrial septal defect occlusion in children and adults.

Expert Rev Cardiovasc Ther 2020 May 22:1-15. Epub 2020 May 22.

Sidra Heart Center, Sidra Medicine , Doha, Qatar.

Introduction: Atrial septal defect (ASD) is one of the most common congenital heart diseases (CHD) in children and adults. This group of malformations includes several types of atrial communications allowing shunting of blood between the systemic and the pulmonary circulations. Early diagnosis and treatment carries favorable outcomes. Read More

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http://dx.doi.org/10.1080/14779072.2020.1767595DOI Listing

Atrial Arrhythmias in Patients With an ASD: Where to From Here?

JACC Clin Electrophysiol 2020 May;6(5):549-551

Department of Cardiology, Royal Melbourne Hospital, Melbourne, Victoria, Australia; Department of Medicine, University of Melbourne, Melbourne, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jacep.2020.01.012DOI Listing

Distribution of Conduction Disorders in Patients With Congenital Heart Disease and Right Atrial Volume Overload.

JACC Clin Electrophysiol 2020 May 26;6(5):537-548. Epub 2020 Feb 26.

Department of Cardiology, Erasmus Medical Center, Rotterdam, the Netherlands. Electronic address:

Objectives: This study sought to quantify characteristics of atrial conduction disorders in patients with right atrial (RA) volume overload.

Background: Patients with an interatrial shunt are prone to developing atrial fibrillation (AF), which may be related to conduction disorders occurring due to atrial stretch.

Methods: Thirty-one patients undergoing surgery for an interatrial shunt (49 ± 14 years of age) underwent epicardial sinus rhythm mapping of the RA, Bachmann's bundle (BB), and left atrium (LA). Read More

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http://dx.doi.org/10.1016/j.jacep.2019.12.009DOI Listing

Normalization of the right heart and the preoperative factors that influence the emergence PAH after surgical closure of atrial septal defect.

J Cardiothorac Surg 2020 May 20;15(1):105. Epub 2020 May 20.

Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.

Background: Surgical closure of atrial septal defect (ASD) is contraindicated in the condition with severe pulmonary arterial hypertension (PAH), whereas ASD closure in an effective intervention to normalize the structure and function of the right heart after previously experiencing volume overload due to shunting from the defect. This study aimed to evaluate normalization of the right heart and emergence of PAH after surgical closure of ASD.

Methods: This retrospective study was carried out in 45 patients over 18 years who had undergone surgical closure of ASD. Read More

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http://dx.doi.org/10.1186/s13019-020-01148-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238627PMC

Transposition of the Great Arteries-Are We Doing Better? Correlating Outcome to Change in Renal Function Over 2 Decades of Arterial Switch Operation.

Pediatr Crit Care Med 2020 May 20. Epub 2020 May 20.

Pediatric Cardiac Intensive Care Unit, Schneider Children's Medical Center of Israel, Petah Tikva, Israel.

Objectives: It is believed that management of neonates with dextro-transposition of the great arteries is constantly improving. Renal function may play a role in the prognosis of patients after congenital heart surgery. The aim of this study was to describe the outcome of neonates who underwent arterial switch operation during the past 2 decades using renal function as a surrogate marker for morbidity and mortality. Read More

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http://dx.doi.org/10.1097/PCC.0000000000002387DOI Listing

Shift From Left to a Right Bundle Block on ECG Leading to the Diagnosis of a Malpositioned Lead in the Coronary Sinus: A Case Report.

Am J Med Case Rep 2020 14;8(7):178-181. Epub 2020 Apr 14.

Division of Cardiovascular Diseases and Department of Internal Medicine, State University of New York, Downstate Medical Center, Brooklyn, NY 11203, U.S.A.

On electrocardiography (ECG), ventricular pacing appears as a spikes that precede induced QRS complexes. The induced complexes with a right ventricular lead have the morphology of a left bundle branch block (LBBB). We describe a case of malposition right ventricular (RV) lead in the coronary sinus diagnosed based on the changes noted in the ECG tracing. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237009PMC

Incidence and Patterns of Congenital Heart Disease Among Jordanian Infants, a Cohort Study From a University Tertiary Center.

Front Pediatr 2020 5;8:219. Epub 2020 May 5.

Department of Pediatrics and Neonatology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.

Data is limited about the incidence of congenital heart disease in Jordan. The goal of this study is to determine the incidence and patterns of congenital heart diseases (CHD) among Jordanian infants evaluated at King Abdullah University Hospital. A retrospective chart review was conducted for all infants who had an echocardiogram evaluation in the 3-years period July 2016-June 2019. Read More

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http://dx.doi.org/10.3389/fped.2020.00219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214919PMC

Multimodality fusion imaging to guide percutaneous sinus venosus atrial septal defect closure.

Eur Heart J 2020 May 18. Epub 2020 May 18.

Department of Congenital Heart Diseases, Centre de Référence Cardiopathies Congénitales Complexes M3C, Hôpital Marie Lannelongue, Groupe Hospitalier Paris Saint Joseph, Université Paris-Sud, 133 avenue de la résistance, 92350 Le Plessis Robinson, France.

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http://dx.doi.org/10.1093/eurheartj/ehaa292DOI Listing

Neuropsychological Status and Structural Brain Imaging in Adults With Simple Congenital Heart Defects Closed in Childhood.

J Am Heart Assoc 2020 Jun 19;9(11):e015843. Epub 2020 May 19.

Department of Cardiothoracic & Vascular Surgery Aarhus University Hospital Aarhus N Denmark.

Background Neurodevelopmental impairments are common in survivors of complex congenital heart defects (CHD). We report neuropsychological and brain imaging assessments in adults operated for isolated septal defects. Methods and Results Patients (mean age 25. Read More

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http://dx.doi.org/10.1161/JAHA.120.015843DOI Listing

Atrial septal defect closure in a midget toy poodle.

Open Vet J 2020 Apr 20;10(1):11-15. Epub 2020 Jan 20.

Department of Veterinary Medicine, Azabu University, Sagamihara, Kanagawa 252-5201, Japan.

Background: Atrial septal defect (ASD) is a rare congenital cardiac disease, and there have been no reports about the treatment of ASD in midget breed dogs.

Case Description: A 7-month-old female toy poodle weighing 1.4 kg presented with cardiac enlargement. Read More

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http://dx.doi.org/10.4314/ovj.v10i1.3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193879PMC

Biological basis of child health 3: development of the cardiovascular system and congenital heart defects.

Authors:
Doreen Crawford

Nurs Child Young People 2020 May 18. Epub 2020 May 18.

Crawford McKenzie consultancy, Colsterworth, England.

This article is the third in a series on the biological basis of child health. It outlines how the cardiovascular system develops during gestation and how congenital heart defects (CHDs) may arise in the process. The article details the pathophysiology and treatment of some of the common CHDs, including patent ductus arteriosus, atrial septal defect, ventricular septal defect and transposition of the great arteries. Read More

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http://dx.doi.org/10.7748/ncyp.2020.e1245DOI Listing

Risk of malformation after ondansetron in pregnancy: An updated systematic review and meta-analysis.

Birth Defects Res 2020 May 18. Epub 2020 May 18.

Service Hospitalo-Universitaire de Pharmaco-Toxicologie, Hospices Civils de Lyon, Lyon, France.

Ondansetron is increasingly used off label to treat nausea and vomiting during pregnancy. The main objective of this study was to evaluate the risk of major congenital malformations (MCM), cardiac defects and orofacial clefts associated with first trimester exposure to ondansetron using a meta-analytic approach. MEDLINE, ClinicalTrials. Read More

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http://dx.doi.org/10.1002/bdr2.1705DOI Listing

Percutaneous Atrial Septal Defect Closure in Adult Ebstein's Anomaly with Exertional Hypoxemia.

Int Heart J 2020 May 15;61(3):620-623. Epub 2020 May 15.

Department of Pediatrics, Jichi Medical University.

In Ebstein's anomaly, percutaneous atrial septal defect (ASD) closure for the treatment of hypoxemia due to a right-to-left interatrial shunt remains controversial. We report the case of a 40-year-old woman with Ebstein's anomaly who developed cyanosis and shortness of breath on exercise. Her symptoms improved after percutaneous ASD closure and her clinical course has been good during follow-up. Read More

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http://dx.doi.org/10.1536/ihj.19-641DOI Listing

Impact of Right Ventricular Dilatation in Patients with Atrial Septal Defect.

J Interv Cardiol 2020 27;2020:9509105. Epub 2020 Apr 27.

Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.

Objective: The aim of this study was to examine the relationship between right ventricular (RV) volume and exercise capacity in adult patients with atrial septal defect (ASD) and to determine the degree of RV dilatation for transcatheter ASD closure.

Background: RV dilatation is an indication of transcatheter ASD closure; however, few studies have reported the clinical significance of RV dilatation.

Methods: We enrolled 82 consecutive patients (mean age, 49 ± 18 years; female, 68%) who underwent cardiac magnetic resonance imaging and symptom-limited cardiopulmonary exercise test before ASD closure. Read More

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http://dx.doi.org/10.1155/2020/9509105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204162PMC
April 2020
1.318 Impact Factor

Personalized Three-Dimensional Printing and Echoguided Procedure Facilitate Single Device Closure for Multiple Atrial Septal Defects.

J Interv Cardiol 2020 25;2020:1751025. Epub 2020 Apr 25.

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100037, China.

Background: To evaluate the feasibility of using a single device to close multiple atrial septal defects (ASDs) under the guidance of transthoracic echocardiography (TTE) and with the aid of three-dimensional (3D) printing models.

Methods: Sixty-two patients with multiple ASDs were retrospectively analyzed. Thirty of these patients underwent TTE-guided closure (3D printing and TTE group) after a simulation of occlusion in 3D printing models. Read More

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http://dx.doi.org/10.1155/2020/1751025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201835PMC

Percutaneous closure of residual atrial septal defect after surgical closure.

Cardiovasc Interv Ther 2020 May 13. Epub 2020 May 13.

Department of Cardiovascular Medicine, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8558, Japan.

Residual atrial septal defect (ASD) after surgical closure is rare, but some cases are seen during follow-up period. Redo surgery for residual ASD is often declined, while percutaneous closure can be acceptable. However, the indication of percutaneous closure for residual ASD has not been established. Read More

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http://dx.doi.org/10.1007/s12928-020-00671-5DOI Listing

Surgical management of embolized Amplatzer septal occluder into the left ventricle tangled with the mitral valve.

J Card Surg 2020 May 12. Epub 2020 May 12.

Department of Cardiac Surgery, Leon University Hospital, Leon, Spain.

Device embolization is a rare major complication of atrial septal defect percutaneous closures which requires surgical management if noninvasive retrieval fails. We report a symptomatic delayed embolization of an Amplatzer septal occluder device into the left ventricle outflow tract tangled with the mitral valve, complicated with ventricular arrhythmias and cardiac tamponade during percutaneous retrieval attempt. Emergent surgical treatment was performed, requiring a combined approach through the right atrium and the aorta for surgical removal. Read More

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http://dx.doi.org/10.1111/jocs.14621DOI Listing

Early Surgical Closure of Atrial Septal Defect Improves Clinical Status of Symptomatic Young Children with Underlying Pulmonary Abnormalities.

Pediatr Cardiol 2020 May 9. Epub 2020 May 9.

Nemours Cardiac Center, Division of Cardiology, Nemours/Alfred I. duPont Hospital for Children, 1600 Rockland Rd., Wilmington, DE, 19803, USA.

Elective closure of atrial septal defect (ASD) is usually recommended during preschool ages. However, ASD may contribute to deteriorating health in the presence of significant comorbidity and, thus, may need earlier closure. There is a lack of clarity regarding the indications for and outcomes after ASD closure in infancy and early childhood. Read More

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http://dx.doi.org/10.1007/s00246-020-02361-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223328PMC

Evaluation of Cardiac Shunts With 4D Flow Cardiac Magnetic Resonance: Intra- and Interobserver Variability.

J Magn Reson Imaging 2020 May 9. Epub 2020 May 9.

Cardiology Department. Quirón-Salud University Hospital, European University of Madrid, Madrid, Spain.

Background: In the last decade, the capacity of magnetic resonance (MR) to evaluate congenital anomalies has improved substantially. To date, only a few studies have evaluated the value of 4D-flow MRI in shunt assessments.

Purpose/hypothesis: To assess the intra- and interobserver variability of 4D-flow MRI in patients diagnosed with cardiac/extracardiac shunt. Read More

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http://dx.doi.org/10.1002/jmri.27158DOI Listing

Acute cerebral infarction with acute myocardial infarction due to patent foramen ovale: A case report.

Medicine (Baltimore) 2020 May;99(19):e20054

Department of Hepatobiliary Surgery, the Fourth Hospital of Hebei Medical University, Shijiazhuang, P. R. China.

Rationale: Patent foramen ovale (PFO) is not considered to be the main cause of stroke and is classified as the infarction of undetermined cause. The relationship between PFO and cerebral embolism is still unclear and cerebral embolism accompanied with coronary artery embolization in PFO patient is rare. In this case, we reported a patient with PFO suffered acute cerebral and myocardial infarction simultaneously, and analyzed the source of emboli and potential pathogenesis. Read More

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http://dx.doi.org/10.1097/MD.0000000000020054DOI Listing

Right atrial appendage aneurysm complicated with atrial septal defect: A rare case report.

Echocardiography 2020 May 7;37(5):788-790. Epub 2020 May 7.

Department of Ultrasound, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China.

Right atrial appendage aneurysms (RAAAs) are rare heart malformations, presenting as isolated anomalies or co-existing with other structural heart diseases. We describe a rare case of RAAA complicated with an atrial septal defect (ASD). The diagnosis was established using transthoracic echocardiography and confirmed using cardiac magnetic resonance imaging. Read More

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http://dx.doi.org/10.1111/echo.14659DOI Listing
May 2020
1.254 Impact Factor

Profile of Endothelin-1, Nitric Oxide, and Prostacyclin Levels in Pulmonary Arterial Hypertension Related to Uncorrected Atrial Septal Defect: Results from a Single Center Study in Indonesia.

Cardiol Res Pract 2020 7;2020:7526508. Epub 2020 Jan 7.

Department of Cardiology and Vascular Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada-Dr. Sardjito Hospital, Yogyakarta, Indonesia.

Methods: The study design was cross-sectional. The subjects were adult uncorrected secundum ASD with PAH. Pulmonary artery pressure was measured with right heart catheterization. Read More

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http://dx.doi.org/10.1155/2020/7526508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199565PMC
January 2020

HYDIN loss-of-function inhibits GATA4 expression and enhances atrial septal defect risk.

Mech Dev 2020 May 3:103611. Epub 2020 May 3.

Department of Cardiovascular Surgery, the First Peoples' Hospital of Yunnan Province, Kunming, Yunnan, PR China. Electronic address:

Background: Mutations affecting cardiac structural genes can lead to congenital heart diseases (CHDs). Axonemal Central Pair Apparatus Protein (HYDIN) is a ciliary protein previously linked to congenital cardiomyopathy. However, the role of HYDIN in the aetiology of CHDs is thus far unknown. Read More

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http://dx.doi.org/10.1016/j.mod.2020.103611DOI Listing
May 2020
2.440 Impact Factor

Importance of identifying the direction of pulmonary venous flow in diagnosing a cavopulmonary window: A case report and review of literature.

J Cardiol Cases 2020 May 26;21(5):179-181. Epub 2020 Mar 26.

Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Japan.

A 75-year-old male suffered from dyspnea on exertion. In a referring hospital, cardiac catheterization demonstrated a 25% increase in oxygen saturation between the high superior vena cava (SVC) and the right atrium, suggesting a pre-tricuspid left-to-right shunt. However, neither an intracardiac shunt nor a partial anomalous pulmonary venous connection was detected. Read More

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http://dx.doi.org/10.1016/j.jccase.2020.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195565PMC

Tricuspid Regurgitation in Ostium Secundum Atrial Septal Defects: Repair or Not?

Heart Surg Forum 2020 04 23;23(2):E239-E244. Epub 2020 Apr 23.

Department of Cardiovascular and Thoracic Surgery, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.

Background: Longstanding ostium secundum atrial septal defects lead to functional tricuspid regurgitation. Significant functional tricuspid regurgitation associated with left heart valve disease is addressed at the time of primary left heart valve surgery. In contrast, there is no global recommendation for tricuspid regurgitation associated with atrial septal defects. Read More

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http://dx.doi.org/10.1532/hsf.2859DOI Listing

Perioperative Risk Factors for Mortality in Patients Undergoing Surgery for Ebstein's Anomaly at a Single Institution: A Retrospective Analysis.

Heart Surg Forum 2020 04 3;23(2):E193-E199. Epub 2020 Apr 3.

Department of Anesthesiology, University Hospitals of Leuven, Leuven, Belgium.

Background: Mortality after cardiac surgery for Ebstein's anomaly ranges from 2.5% to 31%. Independent predictors for mortality and morbidity remain poorly defined because of the low incidence of this congenital anomaly. Read More

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http://dx.doi.org/10.1532/hsf.2755DOI Listing

Hybrid closure of a large atrial septal defect using Occlutech Flex II septal occluder in a patient with interrupted inferior caval vein.

Cardiol Young 2020 May 4:1-3. Epub 2020 May 4.

Department of Pediatrics, Section of Cardiology, Jordan University Hospital, Amman, Jordan.

We present a case of a 31-year-old male with a large atrial septal defect, who was found to have interrupted inferior caval vein with azygous continuation to the superior caval vein, which precluded transcutaneous closure by device. The defect was successfully closed with a 33 mm Occlutech Figula septal occluder using a sub-mammary small thoracotomy incision and per-atrial approach without using cardiopulmonary bypass. The patient was discharged home after 48 hours of procedure. Read More

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http://dx.doi.org/10.1017/S104795112000092XDOI Listing

Chinese patient with neurofibromatosis-Noonan syndrome caused by novel heterozygous NF1 exons 1-58 deletion: a case report.

BMC Pediatr 2020 May 1;20(1):190. Epub 2020 May 1.

Department of Pediatrics, The First Affiliated Hospital of Bengbu Medical College, Bengbu, 233004, Anhui, China.

Background: Neurofibromatosis-Noonan syndrome (NFNS) is a rare autosomal dominant hereditary disease. We present a case of NFNS due to the heterozygous deletion of exons 1-58 of the NF1 gene on chromosome 17 in a 15-month-old boy.

Case Presentation: A 15-month-old boy was admitted for motor and language developmental delay, numerous café-au-lait spots, hypertelorism, left blepharoptosis, pectus excavatum, cryptorchidism, secondary atrial septal defect, and UBOs (undefined bright objects) revealed by cranial MRI T2FLAIR in basal ganglia and cerebellum. Read More

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http://dx.doi.org/10.1186/s12887-020-02102-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193357PMC

Detection of atrial shunt lesions with a single echocardiographic parameter.

Wien Klin Wochenschr 2020 Apr 30. Epub 2020 Apr 30.

Department of Internal Medicine II, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

Background: Unrepaired left to right atrial shunt lesions can cause significant right ventricular (RV) volume overload. The parameter pulmonary to systemic shunt volume ratio (Qp:Qs) has been shown to detect even small differences between left and right ventricular stroke volume; however, four parameters are needed for its calculation. This study was carried out to evaluate the accuracy of the single parameter right ventricular outflow tract (RVOT) velocity time integral (VTI) to identify atrial shunt lesions. Read More

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http://dx.doi.org/10.1007/s00508-020-01659-0DOI Listing

Persistent Left Superior Vena Cava Suggested by an Unusual Central Venous Pressure Waveform.

Thorac Cardiovasc Surg Rep 2020 Jan 28;9(1):e15-e17. Epub 2020 Apr 28.

Department of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, Ohio, United States.

 A persistent left superior vena cava (PLSVC) is the most common congenital anomaly of the thoracic venous return.  During atrial septal defect repair, a pulmonary artery (PA) catheter was placed via the left internal jugular vein. Although placement of the PA catheter in the main PA was confirmed by transesophageal echocardiography, the central venous pressure (CVP) waveform was abnormal. Read More

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http://dx.doi.org/10.1055/s-0040-1708474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188515PMC
January 2020

Children Born with Congenital Heart Defects and Growth Restriction at Birth: A Systematic Review and Meta-Analysis.

Int J Environ Res Public Health 2020 Apr 28;17(9). Epub 2020 Apr 28.

Université de Paris, CRESS, INSERM, INRA, F-75004 Paris, France.

Newborns with congenital heart defects tend to have a higher risk of growth restriction, which can be an independent risk factor for adverse outcomes. To date, a systematic review of the relation between congenital heart defects (CHD) and growth restriction at birth, most commonly estimated by its imperfect proxy small for gestational age (SGA), has not been conducted.

Objective: To conduct a systematic review and meta-analysis to estimate the proportion of children born with CHD that are small for gestational age (SGA). Read More

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http://dx.doi.org/10.3390/ijerph17093056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246925PMC