19,631 results match your criteria Atrial Septal Defect


Assessment of ventricular function in patients of atrial septal defect by strain imaging before and after correction.

Ann Card Anaesth 2019 Jan-Mar;22(1):41-46

Department of Cardiac Anaesthesia, Institute of Post Graduation Medical Education and Research, Kolkata, India.

Background: Atrial septal defect (ASD) is a common congenital heart disease associated with volume overload of Right ventricle (RV) with variable effect on Left ventricle (LV). Two-dimensional (2D) Strain analysis is a new tool for objective analysis of myocardial function. This prospective study evaluated the systolic function of right and left ventricle by conventional 2D echo and strain echo and measured changes in cardiac hemodynamics that occurred in patients of ASD before and after correction. Read More

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http://dx.doi.org/10.4103/aca.ACA_153_17DOI Listing
January 2019

Embolization of high-output idiopathic renal arteriovenous fistula primarily using an atrial septal defect occluder via venous access: a case report.

BMC Nephrol 2019 Jan 11;20(1):15. Epub 2019 Jan 11.

Department of Intervention, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.

Background: The case report is to evaluate the efficacy and safety of embolization of a high-output idiopathic renal arteriovenous fistula (IRAVF) with an atrial septal defect occluder (ASDO) via venous access.

Case Presentation: A 57-year-old male diagnosed with high-output IRAVF received embolization with an ASDO via renal venous access and compact occlusion with 3 vascular plugs and a detachable elastic coil. The IRAVF was successfully occluded. Read More

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https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882
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http://dx.doi.org/10.1186/s12882-019-1200-xDOI Listing
January 2019
1 Read

Selexipag treatment for pulmonary arterial hypertension associated with congenital heart disease after defect correction: insights from the randomised controlled GRIPHON study.

Eur J Heart Fail 2019 Jan 11. Epub 2019 Jan 11.

Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Bologna University Hospital, Bologna, Italy.

Aims: Patients with pulmonary arterial hypertension associated with congenital heart disease (CHD-PAH) after defect correction have a poor prognosis compared with other CHD-PAH patients. Therefore, it is important that these patients are treated as early and effectively as possible. Evidence supporting the use of PAH therapies in patients with corrected CHD-PAH from randomised controlled trials is limited. Read More

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http://doi.wiley.com/10.1002/ejhf.1375
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http://dx.doi.org/10.1002/ejhf.1375DOI Listing
January 2019
1 Read

Influenza B virus infection complicated by life-threatening pericarditis: a unique case-report and literature review.

BMC Infect Dis 2019 Jan 10;19(1):40. Epub 2019 Jan 10.

Unit of Clinical Laboratory Science, University Campus Bio-Medico of Rome, Via Alvaro del Portillo, 200, Rome, Italy.

Background: Acute pericarditis may occur frequently after viral infections. To our knowledge, influenza B virus infection complicated by pericarditis without myocardial involvement has never been reported. We report the first case of life-threatening pericarditis caused by influenza B virus infection. Read More

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12879-018-3606-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327550PMC
January 2019
1 Read

Combined Percutaneous Procedure in Patient with Lutembacher Syndrome: A Case Report and Real-World Experience Review.

Cardiol Res 2018 Dec 7;9(6):385-391. Epub 2018 Dec 7.

Intervention Center, Chung-Ang University Hospital, Seoul 06973, Korea.

Even cardiac surgery has been accepted as the standard therapy for Lutembacher syndrome, a combination of congenital ostium secundum atrial septal defect (ASD) and acquired mitral valve stenosis (MVS), it also owns many limitations and disadvantages. Therefore, seeking for a less invasive therapy with the same efficacy may be worthwhile. Thanks to the development in technology and experience gaining in cardiovascular intervention, the combination of the two proved effective procedures, including percutaneous MVS treatment using balloon valvuloplasty and percutaneous ASD closure using atrial septal occluders, can be utilized as an attractive alternative therapy for these conditions. Read More

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http://www.cardiologyres.org/index.php/Cardiologyres/article
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http://dx.doi.org/10.14740/cr776wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306122PMC
December 2018
1 Read

Total anomalous pulmonary vein drainage in a 60-year-old woman diagnosed in an ECG-gated multidetector computed tomography - a case report and review of literature.

Pol J Radiol 2018 5;83:e334-e339. Epub 2018 Jul 5.

I Department of Medical Radiology, Medical University of Lublin, Lublin, Poland.

Purpose: Total anomalous pulmonary vein drainage (TAPVD) is a congenital cardiac defect in which there is no connection between pulmonary veins and the left atrium. Pulmonary veins form a confluence independent of the left atrium and drain to a systemic vein. TAPVD types are: supracardiac, cardiac, infracardiac, and mixed. Read More

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https://www.termedia.pl/doi/10.5114/pjr.2018.77696
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http://dx.doi.org/10.5114/pjr.2018.77696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323547PMC
July 2018
1 Read

Maternal Overweight and Obesity and Risk of Congenital Heart Defects.

J Am Coll Cardiol 2019 Jan;73(1):44-53

Department of Medicine, Solna, Clinical Epidemiology Unit, Karolinska Institutet, Stockholm, Sweden.

Background: Congenital heart defects are more frequent in offspring of mothers with overweight or obesity. However, associations between maternal overweight and obesity, and risks of complex and specific heart defects are not clear.

Objectives: This study sought to analyze associations between maternal overweight and obesity severity and rates of complex and specific heart defects. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07351097183908
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http://dx.doi.org/10.1016/j.jacc.2018.10.050DOI Listing
January 2019
2 Reads

Persistent left superior vena cava associating with anomalous right superior vena cava drainage, atrial septal defect and atrial fibrillation: a case report.

Chin Med J (Engl) 2019 Jan;132(2):220-222

Department of Cardiology, The affiliated Wuxi No. 2 People's Hospital of Nanjing Medical University, Wuxi, Jiangsu 214000, China.

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http://dx.doi.org/10.1097/CM9.0000000000000044DOI Listing
January 2019
1 Read
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Pulmonary Vascular Resistance Index: Getting the Units Right and Why it Matters.

Clin Cardiol 2019 Jan 4. Epub 2019 Jan 4.

Division of Cardiovascular Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, California.

Pulmonary vascular resistance (PVR) and pulmonary vascular resistance index (PVRI) are key variables in a broad range of contexts, including prediction of outcomes in heart and liver transplantation, determining candidacy for closure of atrial or ventricular septal defects, and guiding treatment of pulmonary hypertension. Significant variability exists among the units used to report PVRI in current literature, making the interpretation of data and translation into clinical practice difficult. Here we will review the measurement and derivation of PVR and PVRI and demonstrate the extent of confusion in the literature. Read More

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http://doi.wiley.com/10.1002/clc.23151
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http://dx.doi.org/10.1002/clc.23151DOI Listing
January 2019
1 Read

More than an atrial septal defect.

J Cardiovasc Comput Tomogr 2018 Dec 22. Epub 2018 Dec 22.

Vila Nova de Gaia/Espinho Hospital Centre, Porto, Rua Conceição Fernandes 1282, Vila Nova de Gaia, Portugal.

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https://linkinghub.elsevier.com/retrieve/pii/S19345925183029
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http://dx.doi.org/10.1016/j.jcct.2018.12.054DOI Listing
December 2018
1 Read

Transcatheter Closure of Atrial Septal Defects: Comparable Experience and Outcomes Between Developing and Developed Countries.

Pediatr Cardiol 2019 Jan 3. Epub 2019 Jan 3.

Department of Pediatrics and Adolescent Medicine, American University of Beirut Medical Center (AUBMC), Beirut, Lebanon.

Atrial septal defect (ASD) is one of the most common congenital heart defects. Transcatheter device closure of ASDs is safe and effective with most of the reported data being described from developed countries. To evaluate the short and mid-term results and experience of device closure of ASDs at a tertiary center in a developing country and compare it to that from developed countries. Read More

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http://link.springer.com/10.1007/s00246-018-2034-1
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http://dx.doi.org/10.1007/s00246-018-2034-1DOI Listing
January 2019
1 Read

Long-term outcome of catheter ablation for atrial tachyarrhythmias in patients with atrial septal defect.

J Interv Card Electrophysiol 2019 Jan 3. Epub 2019 Jan 3.

Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.

Purpose: This study aimed to evaluate efficacy, safety, and long-term outcome of radiofrequency catheter ablation (RFCA) for atrial tachyarrhythmia (ATa) in patients with atrial septal defect (ASD).

Methods: Seventy-five ASD patients with ATa (52% atrial fibrillation, AF) were enrolled. Electrophysiological study and RFCA were performed, with endpoints of index and multiple procedures as follows: (a) atrial tachycardia/atrial flutter (AT/AFL), absence of inducibility of any atrial arrhythmia and (b) AF, circumferential pulmonary vein ablation (CPVA, paroxysmal AF), bidirectional block of lines, and disappearance of complex fractionated atrial electrograms (persistent and long-standing persistent (LSP)-AF). Read More

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http://dx.doi.org/10.1007/s10840-018-0505-1DOI Listing
January 2019
1 Read

Unroofed coronary sinus atrial septal defect.

J Card Surg 2019 Jan 30;34(1):41-42. Epub 2018 Dec 30.

Department of Radiology, Institute of Cardiology, Warsaw, Poland.

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http://dx.doi.org/10.1111/jocs.13971DOI Listing
January 2019

68-year-old woman with paroxysmal atrial fibrillation.

Heart 2018 Dec 28. Epub 2018 Dec 28.

Department of Cardiothoracic Surgery, Onassis Cardiac Surgery Center, Athens, Greece.

Question: What is the most likely diagnosis?Mitral stenosis.Pericardial cyst.Left atrial appendage aneurysm. Read More

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http://dx.doi.org/10.1136/heartjnl-2018-314143DOI Listing
December 2018
1 Read

Maternal residential exposure to specific agricultural pesticide active ingredients and birth defects in a 2003-2005 North Carolina birth cohort.

Birth Defects Res 2018 Dec 28. Epub 2018 Dec 28.

Office of Research and Development, U.S. Environmental Research Triangle Park, Research Triangle Park, North Carolina.

Background: Previously we observed elevated odds ratios (ORs) for total pesticide exposure and 10 birth defects: three congenital heart defects and structural defects affecting the gastrointestinal, genitourinary and musculoskeletal systems. This analysis examines association of those defects with exposure to seven commonly applied pesticide active ingredients.

Methods: Cases were live-born singleton infants from the North Carolina Birth Defects Monitoring Program linked to birth records for 2003-2005; noncases served as controls (total n = 304,906). Read More

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http://doi.wiley.com/10.1002/bdr2.1448
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http://dx.doi.org/10.1002/bdr2.1448DOI Listing
December 2018
1 Read

Short-term outcomes after surgical versus trans catheter closure of atrial septal defects; a study from Iran.

Egypt Heart J 2018 Dec 17;70(4):249-253. Epub 2018 Sep 17.

Department of Cardiac Anesthesiology, Seyyed-al-Shohada Heart Center, Urmia University of Medical Sciences, Urmia, Iran.

Objectives: Atrial Septal Defect (ASD) accounts for 10% of congenital cardiac defects. The purpose of this retrospective study was to compare the short-term outcomes of surgical versus trans catheter closure of secundum atrial septal defect.

Methods: This is a single-center retrospective cohort study in patients who had surgical or trans catheter ASD closure. Read More

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http://dx.doi.org/10.1016/j.ehj.2018.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303347PMC
December 2018

Immediate and short term effects of percutaneous atrial septal defect device closure on cardiac electrical remodeling in children.

Egypt Heart J 2018 Dec 8;70(4):243-247. Epub 2018 Mar 8.

Cardiology Department, Ain Shams University Hospital, Cairo, Egypt.

Background: The beneficial effects of atrial septal defect (ASD) device closure on electrical cardiac remodeling are well established. The timing at which these effects starts to take place has yet to be determined.

Objectives: To determine the immediate and short term effects of ASD device closure on cardiac electric remodeling in children. Read More

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http://dx.doi.org/10.1016/j.ehj.2018.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303477PMC
December 2018

[Redo Valve Replacement of Wada-Cutter Prosthetic Valve at Tricuspid Valve Position 47 Years After Implantation;Report of a Case].

Kyobu Geka 2018 Dec;71(13):1118-1121

Department of Cardiovascular Surgery, Tokyo Metropolitan Hiroo Hospital, Tokyo, Japan.

We experienced an explantation of Wada-Cutter prosthetic tilting disk valve of 47 years after implantation. The patient was 53 years old female who underwent the 1st operation for Ebstein's anomaly, which included tricuspid valve replacement (TVR), closure of atrial septal defect (ASD) and posterior annulorrhaphy when she was 6 years old. She was doing well after the 1st operation without symptom,but dyspnea and systemic edema worsened recently though increased admission of diuretics. Read More

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December 2018
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Small unrepaired atrial septal defects display impaired exercise capacity compared with healthy peers.

Congenit Heart Dis 2018 Dec 24. Epub 2018 Dec 24.

Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Aarhus, Denmark.

Objective: Adult patients with small, unrepaired atrial septal defects have an increased risk of pneumonia, atrial fibrillation, and stroke. Furthermore, they have higher late mortality than the background population. The functional capacity is unknown in these patients. Read More

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http://dx.doi.org/10.1111/chd.12740DOI Listing
December 2018

Percutaneous closure of persistent atrial septal defects after pulmonary vein isolation.

Cardiovasc Revasc Med 2018 Nov 22. Epub 2018 Nov 22.

Department of Cardiology, Geisinger Medical Center, 100 North Academy Drive, Danville, PA, United States of America.

Pulmonary vein isolation (PVI) with radiofrequency or cryoballoon ablation to treat atrial fibrillation requires trans-septal puncture. This creates a small iatrogenic atrial septal defect (iASD). In most patients, the defect spontaneously closes after 3-6 months. Read More

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http://dx.doi.org/10.1016/j.carrev.2018.10.020DOI Listing
November 2018

Early Outcomes of Cardiac Surgery in Patients with Noonan Syndrome.

Semin Thorac Cardiovasc Surg 2018 Dec 18. Epub 2018 Dec 18.

Departments of Cardiovascular Surgery, Mayo Clinic, Rochester, MN.

Objective: There is a paucity of cardiac surgery outcomes data for patients with Noonan syndrome (NS). Our objective was to evaluate early results in these patients.

Methods: Between January 1999-December 2015, 29 patients (18 males, 62%) with NS underwent cardiac surgery at our institution. Read More

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http://dx.doi.org/10.1053/j.semtcvs.2018.12.004DOI Listing
December 2018
1 Read

Fulminant cytomegalovirus myocarditis in an infant with concomitant large atrial and ventricular septal defects: medical intervention strategy for functional cardiac regeneration.

Cardiol Young 2018 Dec 21:1-3. Epub 2018 Dec 21.

Pediatric Cardiology,Goethe University,Frankfurt/Main,Germany.

A cytomegalovirus-associated heart failure in a young infant with atrial and ventricular septal defects is reported in this case report. The patient recovered by an anti-congestive and anti-viral therapy with an extra percutaneous transcatheter treatment strategy. In the context of bi-ventricular predominant right heart failure associated with supra-systemic pulmonary hypertension, the already closed arterial duct was re-opened and stented to unload the right ventricle and thereby augment the systemic blood flow. Read More

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https://www.cambridge.org/core/product/identifier/S104795111
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http://dx.doi.org/10.1017/S1047951118002160DOI Listing
December 2018
4 Reads

Projected Future Cancer Risks in Children Treated With Fluoroscopy-Guided Cardiac Catheterization Procedures.

Circ Cardiovasc Interv 2018 Nov;11(11):e006765

Ionizing Radiation Epidemiology Laboratory (LEPID) (N.J., E.R., F.D.Z.-B., D.L., M.-O.B., H.B.).

Background Children treated with cardiac catheterization procedures have now a long life expectancy and consequently potential long-term radiation-induced risks. We projected lifetime attributable risks (LARs) of cancer incidence from the most frequent procedures in pediatrics: atrial septal defect closure, patent ductus arteriosus occlusion, or pulmonary valvuloplasty. Methods and Results Organ equivalent doses were estimated for 1251 procedures performed in children aged ≤15 years at 2 reference catheterization centers in France from 2009 to 2013. Read More

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.118.006765DOI Listing
November 2018

Assessment of the Right and Left Atrial Functions at Midterm After Surgical and Device Atrial Septal Defect Closure: A 2-Dimensional Speckle-Tracking Echocardiographic Study.

J Ultrasound Med 2018 Dec 20. Epub 2018 Dec 20.

Department of Cardiology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.

Objectives: The available literature lacks data on the comparison of the functions of the right atrium (RA) and left atrium (LA) between surgical atrial septal defect (ASD) closure and percutaneous device ASD closure at follow-up durations of longer than 1 year. We sought to evaluate the RA and LA functions in patients who underwent surgical or device ASD closure between 1 and 5 years postprocedurally.

Methods: The study population included 30 patients who underwent device ASD closure and 30 who underwent surgical ASD closure, who were matched for the procedural time, age, and sex, in addition to 30 control participants. Read More

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http://dx.doi.org/10.1002/jum.14887DOI Listing
December 2018

Superior sinus venosus atrial septal defect with anomalous pulmonary venous drainage.

BMJ Case Rep 2018 Nov 28;11(1). Epub 2018 Nov 28.

Department of Surgery, Mater Dei Hospital, Msida, Malta.

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http://dx.doi.org/10.1136/bcr-2018-225596DOI Listing
November 2018

Echocardiography guided bed side balloon atrial septostomy in dextro transposed great arteries (dTGA) with intact ventricular septum (IVS): A resource limited country experience.

Pak J Med Sci 2018 Nov-Dec;34(6):1347-1352

Najma Patel, FCPS, FSCAI, Professor and Head of the Department, Paediatric Cardiology, NICVD Karachi, Pakistan.

Objective: To determine effectiveness and safety of echocardiography guided bed side Balloon Atrial Septostomy (BAS) in dextro transposition of great Arteries (dTGA) with intact ventricular septum (IVS) at a public sector tertiary care hospital Karachi, Pakistan.

Methods: This case series include 40 patients with echocardiographic findings of dTGA with IVS and restricted PFO (≤ 2mm) who underwent bedside BAS at department of pediatric cardiology NICVD, Karachi, Pakistan. We recorded pre and post BAS diameter of PFO/Atrial Septal Defect (ASD), oxygen saturation (SpO %), and post procedure complications and outcome. Read More

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http://pjms.com.pk/index.php/pjms/article/view/15792
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http://dx.doi.org/10.12669/pjms.346.15792DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290203PMC
December 2018
4 Reads

Prolonged Activated Clotting Time Immediately Prior to Open Cardiac Surgery.

Ochsner J 2018 ;18(4):423-424

The University of Queensland School of Medicine, Ochsner Clinical School, New Orleans, LA.

Background: Prekallikrein deficiency is an extremely rare disorder in which functional prekallikrein in the plasma is reduced or absent.

Case Report: We present the case of a 15-year-old male with prolonged activated clotting time incidentally noted preoperatively prior to repair of an atrial septal defect. The patient was subsequently found to have prekallikrein (Fletcher factor) deficiency. Read More

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http://dx.doi.org/10.31486/toj.18.0087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292471PMC
January 2018
1 Read

Pulmonary inhalation-perfusion scintigraphy in the evaluation of bronchoscopic treatment of bronchopleural fistula.

Radiol Bras 2018 Nov-Dec;51(6):385-390

Nuclear Medicine Division, Instituto de Radiologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (InRad/HC-FMUSP), São Paulo, SP, Brazil.

Objective: To evaluate the use of pulmonary inhalation-perfusion scintigraphy as an alternative method of investigation and follow-up in patients with bronchopleural fistula (BPF).

Materials And Methods: Nine patients with BPFs were treated through the off-label use of a transcatheter atrial septal defect occluder, placed endoscopically, and were followed with pulmonary inhalation-perfusion scintigraphy, involving inhalation, via a nebulizer, of 900-1300 MBq (25-35 mCi) of technetium-99m-labeled diethylenetriaminepentaacetic acid and single-photon emission computed tomography with a dual-head gamma camera.

Results: In two cases, there was a residual air leak that was not identified by bronchoscopy or the methylene blue test but was detected only by pulmonary inhalation-perfusion scintigraphy. Read More

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S
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http://dx.doi.org/10.1590/0100-3984.2017.0133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290752PMC
December 2018
6 Reads

Mimic of Atrial Septal Defect.

Circ Cardiovasc Imaging 2018 Dec;11(12):e008410

Division of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China.

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http://dx.doi.org/10.1161/CIRCIMAGING.118.008410DOI Listing
December 2018

Holt-Oram syndrome: clinical and molecular description of 78 patients with TBX5 variants.

Eur J Hum Genet 2018 Dec 14. Epub 2018 Dec 14.

CHU Lille, Clinique de Génétique, 59000, Lille, France.

Holt-Oram syndrome (HOS) is an autosomal dominant condition characterised by the association of congenital heart defect (CHD), with or without rhythm disturbances and radial defects, due to TBX5 variants. The diagnosis is challenged by the variability of expression and the large phenotypic overlap with other conditions, like Okihiro syndrome, TAR syndrome or Fanconi disease. We retrospectively reviewed 212 patients referred for suspicion of HOS between 2002 and 2014, who underwent TBX5 screening. Read More

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http://dx.doi.org/10.1038/s41431-018-0303-3DOI Listing
December 2018

Fracture of a Transcatheter Atrial Septal Defect Occluder Device Causing Mitral Valve Perforation.

Ann Thorac Surg 2018 Dec 11. Epub 2018 Dec 11.

Department of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland; Department of Cardiovascular Surgery, University Hospital Zurich, Zurich, Switzerland.

Transcatheter atrial septal defect (ASD) device closure has gained increasing popularity over the past decades due to shorter hospital stay and the absence of skin scars. However, concern about the seriousness of device-related complications is accumulating. We report a case of device fracture in a young asymptomatic woman almost 4 years after percutaneous secundum ASD closure, resulting in mitral valve perforation. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2018.11.015DOI Listing
December 2018
5 Reads

Minimally Invasive Periareolar Approach to Cor Triatriatum Repair.

Innovations (Phila) 2018 Nov/Dec;13(6):445-447

From the Division of Cardiac Surgery.

Cor triatriatum sinister is an uncommon cardiac abnormality characterized by a membrane that divides the left atrium into two chambers. Definitive management requires surgical resection, traditionally through sternotomy. Minimally invasive reparative techniques are associated with reduced blood loss, shorter hospitalization, faster recovery time, and improved cosmesis with excellent patient satisfaction. Read More

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http://dx.doi.org/10.1097/IMI.0000000000000565DOI Listing
December 2018

Reducing Radiation Exposure in Cardiac Catheterizations for Congenital Heart Disease.

Pediatr Cardiol 2018 Dec 12. Epub 2018 Dec 12.

Pediatric Cardiology, Yale School of Medicine, 333 Cedar St, LLCI 302, New Haven, CT, 06510, USA.

Ionizing radiation exposure is a necessary risk entailed during congenital cardiac catheterizations. The congenital catheterization lab at Yale New Haven Children's Hospital employed quality improvement strategies to minimize radiation exposure in this vulnerable population. In two phases, we implemented six interventions, which included adding and utilizing lower fluoroscopy and digital angiography (DA) doses, increasing staff and physician radiation awareness, focusing on tighter collimation, and changing the default fluoroscopy and DA doses to lower settings. Read More

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http://dx.doi.org/10.1007/s00246-018-2039-9DOI Listing
December 2018

Combined perventricular closure of ventricular septal defect and atrial septal defect via lower ministernotomy.

J Cardiothorac Surg 2018 Dec 12;13(1):125. Epub 2018 Dec 12.

Department of Cardiovascular Surgery, West China Hospital, Sichuan University, Guoxuexiang 37th, 610041, Chengdu, Sichuan, People's Republic of China.

Background: Minimally invasive approaches such as perventricular closure of ventricular septal defects (VSD) have been applied for the surgical correction of congenital heart defects in order to avoid disadvantages related to median sternotomy with a cardiopulmonary bypass (CPB). However, reports remain scarce regarding combined perventricular closure of VSD and atrial septal defects (ASD) via minimally invasive approaches, such as lower ministernotomy.

Results: The authors have operated on 5 patients who were diagnosed with VSD in association with ASD, successfully realizing perventricular closure via lower ministernotomy. Read More

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http://dx.doi.org/10.1186/s13019-018-0815-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292104PMC
December 2018

Simultaneous operative repair of pectus excavatum and concurrent congenital heart defects.

Interact Cardiovasc Thorac Surg 2018 Dec 11. Epub 2018 Dec 11.

Department of Cardiothoracic Surgery, Hunan Children's Hospital, Changsha, China.

Objectives: The aim of this study is to describe an effective surgical strategy for the treatment of children with pectus excavatum (PE) and concurrent congenital heart defect (CHD).

Methods: We retrospectively reviewed the medical records of all children (n = 16) who underwent simultaneous repair of PE with concurrent CHD at the Hunan Children's Hospital from July 2007 to December 2017. Among them, 7 patients had a simple atrial septal defect (ASD); 4 patients had a simple ventricular septal defect (VSD); 3 patients had both VSD and ASD; 1 patient had VSD, ASD and patent ductus arteriosus; and 1 patient had VSD complicated by pulmonary hypertension. Read More

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https://academic.oup.com/icvts/advance-article/doi/10.1093/i
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http://dx.doi.org/10.1093/icvts/ivy294DOI Listing
December 2018
12 Reads

Functional and structural studies of tolloid-like 1 mutants associated with atrial-septal defect 6.

Biosci Rep 2019 Jan 8;39(1). Epub 2019 Jan 8.

Department of Molecular Biology and Genetics, School of Medicine in Katowice, Medical University of Silesia in Katowice, Katowice, Poland

Inactive () and mutations detected in tolloid-like 1 () have been linked to the lack of the heart septa formation in mice and to a similar human inborn condition called atrial-septal defect 6 (ASD6; OMIM 613087, formerly ASD II). Previously, we reported four point mutations in found in approximately 20% of ASD6 patients. Three mutations in the coding sequence were M182L, V238A, and I629V. Read More

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http://bioscirep.org/lookup/doi/10.1042/BSR20180270
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http://dx.doi.org/10.1042/BSR20180270DOI Listing
January 2019
1 Read

Identification of Two Mutations in PCDHGA4 and SLFN14 Genes in an Atrial Septal Defect Family.

Curr Med Sci 2018 Dec 7;38(6):989-996. Epub 2018 Dec 7.

Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.

Atrial septal defect (ASD) is a common acyanotic congenital cardiac disorder associated with genetic mutations. The objective of this study was to identify the genetic factors in a Chinese family with ASD patients by a whole exome sequencing approach. Causative ASD gene mutations were examined in 16 members from a three-generation family, among which 6 individuals were diagnosed as having ASD. Read More

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http://link.springer.com/10.1007/s11596-018-1974-2
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http://dx.doi.org/10.1007/s11596-018-1974-2DOI Listing
December 2018
4 Reads

Atrial Septal Defects Accelerate Pulmonary Hypertension Diagnoses in Premature Infants.

Front Pediatr 2018 23;6:342. Epub 2018 Nov 23.

Department of Pediatrics, Emory University, Atlanta, GA, United States.

Between 4 and 16% of extremely premature infants have late pulmonary hypertension (PH) (onset >30 days of life), and infants with PH have a higher risk of tracheostomy and death. Atrial septal defects (ASD) increase pulmonary blood flow and may promote PH in at-risk infants. The objective of this study was to determine if infants with ASD develop PH sooner than those without ASD. Read More

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http://dx.doi.org/10.3389/fped.2018.00342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266546PMC
November 2018
1 Read

Successful heart transplantation in a patient with Loeys-Dietz Syndrome.

Ann Thorac Surg 2018 Dec 1. Epub 2018 Dec 1.

Division of Cardiac Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.

Our patient is a 45-year-old woman with a history of Loeys-Dietz syndrome (LDS), vertebral artery dissection, stroke, prior atrial septal defect (ASD) repair, and spontaneous left main coronary artery dissection re-vascularized with coronary artery bypass grafting who progressed to end-stage heart failure. She was listed for cardiac transplantation and a suitable organ became available. She underwent heart transplantation over one year ago successfully. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2018.10.058DOI Listing
December 2018
2 Reads

Antiplatelet therapy in valvular and structural heart disease interventions.

Cardiovasc Diagn Ther 2018 Oct;8(5):678-693

Unit of Cardiac Sciences, Campus Bio-Medico University of Rome, Rome, Italy.

Transcatheter interventions for valvular and structural heart diseases are rapidly expanding due to greater operators' experience and development of new generation devices associated with increased procedural safety. They represent the standard strategy for patients with prohibitive risk for open surgery. These procedures are associated with a significant occurrence of both thrombotic and bleeding complications, thus in this setting, even more than in other percutaneous procedures, the balance between thrombotic and bleeding risk is critical. Read More

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http://dx.doi.org/10.21037/cdt.2018.06.08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232349PMC
October 2018

Dysrhythmias in patients with a complete atrioventricular septal defect: From surgery to early adulthood.

Congenit Heart Dis 2018 Nov 28. Epub 2018 Nov 28.

Department of Cardiothoracic Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands.

Objective: Outcomes after surgical repair of complete atrioventricular septal defect (cAVSD) have improved. With advancing age, the risk of development of dysrhythmias may increase. The aims of this study were to (1) examine development of sinus node dysfunction (SND), atrial and ventricular tachyarrhythmias, and (2) study progression of atrioventricular conduction abnormalities in young adult patients with repaired cAVSD. Read More

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http://dx.doi.org/10.1111/chd.12724DOI Listing
November 2018
1 Read

Left atrial pressure is associated with iatrogenic atrial septal defect after mitral valve clip.

Heart 2018 Nov 27. Epub 2018 Nov 27.

Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.

Objectives: Mitral valve (MV) clip procedure requires interatrial trans-septal puncture to access the left atrium (LA). Iatrogenic atrial septal defect (iASD) is not uncommon and may remain for a while. However, haemodynamic and echocardiographic determinants of persistent iASD are not well investigated. Read More

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http://heart.bmj.com/lookup/doi/10.1136/heartjnl-2018-313839
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http://dx.doi.org/10.1136/heartjnl-2018-313839DOI Listing
November 2018
13 Reads

Prenatal exposure to PM and Congenital Heart Diseases in Taiwan.

Sci Total Environ 2019 Mar 20;655:880-886. Epub 2018 Nov 20.

Department of Environmental and Occupational Medicine, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan; National Institute of Environmental Health Sciences, National Health Research Institutes, Miaoli, Taiwan; Institute of Occupational Medicine and Industrial Hygiene, National Taiwan University College of Public Health, Taipei, Taiwan. Electronic address:

Gestational exposure to ambient air pollution has been associated with Congenital Heart Diseases (CHDs). However, only a few studies, with inconsistent results, have investigated the effects of PM exposure during early pregnancy. This study aims to evaluate the association between prenatal exposure to PM and CHDs occurrence. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00489697183464
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http://dx.doi.org/10.1016/j.scitotenv.2018.11.284DOI Listing
March 2019
7 Reads

Simultaneous Intraoperative Delivery of Inhaled Epoprostenol and Nitric Oxide in a Neonate for Atrial Septal Defect Closure: First Report of a Novel Technique.

J Cardiothorac Vasc Anesth 2018 Oct 27. Epub 2018 Oct 27.

Department of Anesthesiology and Perioperative Medicine, Division of Cardiovascular and Thoracic Anesthesiology, Mayo Clinic School of Medicine, Scottsdale, AZ.

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http://dx.doi.org/10.1053/j.jvca.2018.10.037DOI Listing
October 2018

Surgical repair of partial anomalous pulmonary venous return with intact atrial septum in a 65-year-old woman: a case report.

J Med Case Rep 2018 Nov 24;12(1):350. Epub 2018 Nov 24.

Department of General and Cardiothoracic Surgery, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu City, 501-1194, Japan.

Background: Partial anomalous pulmonary venous return is a rare congenital cardiac anomaly that usually involves the right pulmonary vein and an atrial septal defect. Isolated partial anomalous pulmonary venous return with an intact atrial septum is even rarer, and this condition is usually treated surgically in younger patients. We describe isolated partial anomalous pulmonary venous return in a 65-year-old woman who was treated by caval division with pericardial patch baffling through a surgically created atrial septal defect and reconstruction of the superior vena cava using a prosthetic graft. Read More

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http://dx.doi.org/10.1186/s13256-018-1874-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260651PMC
November 2018
8 Reads