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Clin Ophthalmol 2021 14;15:2455-2472. Epub 2021 Jun 14.

Motwani LASIK Institute, San Diego, CA, 92121, USA.

Purpose: To investigate the outcomes of the treatment of keratoconus/corneal ectasia utilizing topographic-guided ablation (WaveLight Contoura) followed by corneal cross-linking.

Methods: Thirty-six eyes of 21 patients were treated for keratoconus/corneal ectasia utilizing topographic guided ablation photorefractive keratectomy (PRK) for treatment of corneal higher-order aberrations and refractive error followed immediately by 15-minute cross-linking were examined retrospectively. Six-month results were analyzed via measurement of vision, refraction, residual higher-order aberrations (HOAs), residual lower-order and higher-order aberrations, as well as for loss or gains of lines of best-corrected visual acuity. Read More

J Fr Ophtalmol 2021 Jun 17. Epub 2021 Jun 17.

CHNO des Quinze-Vingts, IHU Foresight, INSERM-DGOS CIC 1423, 28, rue de Charenton, 75012 Paris, France; Inserm, CNRS, Sorbonne Université, institut de la Vision, 17, rue Moreau, 75012 Paris, France. Electronic address:

Regression after corneal refractive surgery is a complex phenomenon which seems inevitable. The choice of surgical technique has very little influence on regression for low myopia or myopic astigmatism. However, LASIK and SMILE are the two techniques of choice in the correction of high myopia. Read More

Optom Vis Sci 2021 Jun;98(6):557-562

Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Shandong, China.

Significance: Highly irregular cornea leads to poor vision, glare, and starbursts. Although treatment is still at the exploration stage, topography-guided Contoura surgery has excellent potential for the treatment of highly irregular corneas.

Purpose: This case series reviews three patients (one with abnormal back elevation, one with corneal scar after fungal keratitis, and one with post-laser-assisted in situ keratomileusis central islands) treated with topography-guided Contoura surgery. Read More

J Refract Surg 2021 Mar 18;37(3):166-173. Epub 2021 Mar 18.

Purpose: To compare refractive outcomes, higher order aberrations (HOAs), and the changes in contrast sensitivity after wavefront-guided femtosecond laser-assisted in situ keratomileusis (WFG LASIK) and optimized small incision lenticule extraction (SMILE) for moderate-to-high astigmatism correction.

Methods: This prospective, randomized study included 87 eyes: 40 eyes in the WFG LASIK group and 47 eyes in the SMILE group. Manual cyclotorsion compensation by marking the horizontal axis before SMILE surgery was used for optimized SMILE. Read More

Semin Ophthalmol 2021 May 19:1-7. Epub 2021 May 19.

Specialty Eye Hospital Svjetlost, School of Medicine, University of Rijeka, Zagreb, Croatia.

: To compare predicted and measured changes in astigmatism at the posterior corneal surface (PCS) after FsLASIK or LASIK.: Astigmatism was measured at both corneal surfaces (Pentacam) before and 3 months after unremarkable FFsLASIK (roup 1,n = 100) or LLASIK (roup 2,n = 100) for myopia (-7.25DS to -0. Read More

Ophthalmol Ther 2021 May 19. Epub 2021 May 19.

Hoopes Vision Research Center, Draper, UT, USA.

Introduction: Laser-assisted in-situ keratomileusis (LASIK) for the correction of hyperopia and hyperopic astigmatism is challenging and has been less studied than for the correction of myopia and myopic astigmatism. The aim of this study was to analyze the refractive outcomes of LASIK in hyperopia and hyperopic astigmatic eyes using a wave-front optimized laser platform (the Allegretto EX500 laser) and perform a historical comparison with other excimer lasers within the past two decades.

Methods: A one-center (Tertiary Refractive Center, Draper, Utah), retrospective, non-comparative study was conducted on 379 eyes treated with LASIK for hyperopia and hyperopic astigmatism. Read More

Med Clin North Am 2021 May 2;105(3):445-454. Epub 2021 Apr 2.

McKnight Vision Research Center, Bascom Palmer Eye Institute, University of Miami-Miller School of Medicine, 900 Northwest 17th Street, Miami, FL 33136, USA.

Cataract surgery is one of the most common surgical procedures performed in the United States. The decision to remove a cataract is determined by the patient's ability to perform activities of daily living, such as reading, driving, and watching television. Cataract surgery also offers the potential of spectacle independence with a wide array of premium intraocular lens options. Read More

Math Biosci Eng 2021 03;18(3):2442-2454

Key Laboratory of Nondestructive Test (Ministry of Education), Nanchang Hangkong University, Nanchang 330063, China.

We studied the effects of the aspheric transition zone on the optical wavefront aberrations, corneal surface displacement, and stress induced by the biomechanical properties of the cornea after conventional laser in situ keratomileusis (LASIK) refractive surgery. The findings in this study can help improve visual quality after refractive surgery. Hyperopia correction in 1-5D was simulated using five types of aspheric transition zones with finite element modeling. Read More

Int J Ophthalmol 2021 18;14(4):523-528. Epub 2021 Apr 18.

Beijing Tongren Hospital Affiliated to Capital Medical University, Beijing Tongren Eye Center, Beijing Ophthalmology & Visual Science Key Lab, Beijing 100730, China.

Aim: To compare the effect of myopia and astigmatism correction and postoperative change in higher-order aberration as results of receiving small-incision lenticule extraction (SMILE) and femtosecond laser-assisted keratomileusis (FS-LASIK).

Methods: A prospective and non-randomized controlled study was conducted. The subjects are divided into two groups according to different operations received: 229 eyes of 116 patients in the SMILE group and 168 eyes of 86 patients in the FS-LASIK group. Read More

BMC Ophthalmol 2021 Apr 16;21(1):181. Epub 2021 Apr 16.

Augenlaserzentrum Neu-Ulm, Edisonallee 19, 89231, Neu-Ulm, Germany.

Purpose: To compare early clinical outcomes of single-step transepithelial photorefractive keratectomy (tPRK) and photorefractive keratectomy (PRK) regarding refractive outcome, visual acuity, wound healing, pain intensity and visual recovery time.d.

Methods: In this prospective clinical observational study 200 eyes of 100 consecutive patients with mild to moderate myopia with or without mild astigmatism were included. Read More

BMC Ophthalmol 2021 Apr 13;21(1):177. Epub 2021 Apr 13.

Department of Ophthalmology, Kaohsiung Veterans General Hospital, 386, Ta-Chung 1st Road, 813, Kaohsiung City, Taiwan.

Background: Traumatic dislocation of laser-assisted in situ keratomileusis (LASIK) corneal flaps is an uncommon postoperative complication that could occur any time after LASIK, and could be visually devastating. We evaluated the visual outcomes, corneal sensation, tear function, and dry eye questionnaire results of patients with traumatic dislocation of LASIK flaps, including one LASIK flap amputation.

Methods: This is a retrospective case series. Read More

Semin Ophthalmol 2021 May 6;36(4):140-148. Epub 2021 Apr 6.

Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.

The emergence of SMILE in the last decade has provided an alternative to LASIK for patients considering cornea laser refractive surgery. SMILE offers a novel approach using the femtosecond laser to create an intrastromal lenticule that can be removed through a small three to four millimeter incision.The purpose of this study is to review the recent literature on popular SMILE claims - reduced iatrogenic dry eye, better recovery of corneal sensation, and a biomechanically stronger cornea - summarize the published outcomes, and determine which claims are myths versus realities. Read More

Int Ophthalmol 2021 Mar 30. Epub 2021 Mar 30.

Joint Shantou International Eye Center of Shantou University, The Chinese University of Hong Kong, Shantou, 515041, China.

Purposes: To retrospectively compare the short-term refractive outcomes and corneal aberrations after small-incision lenticule extraction (SMILE) and femtosecond-assisted laser-assisted in situ keratomileusis (FS-LASIK) combined with smart pulse technology (SPT) in patients with compound myopic astigmatism.

Methods: A total of 91 eyes (91 patients) were included, 43eyes in FS-LASIK group and 48 eyes in the SMILE group. Uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), refractive results and corneal topography were evaluated 1 and 3 months postoperatively. Read More

Int Ophthalmol 2021 Mar 24. Epub 2021 Mar 24.

Department of Ophthalmology, College of Medicine, King Saud University, Airport Road, P.O. Box 245, Riyadh, 11411, Saudi Arabia.

Purpose: To assess the safety and effectiveness of transepithelial photorefractive keratectomy (T-PRK) in patients with mild myopia using the Schwind Amaris 750 s Excimer laser system which take corneal epithelium variability in consideration during ablation.

Methods: A prospective case series study of patients with mild myopia with or without astigmatism (spherical equivalent ≤ -3 diopters), who underwent T-PRK as a single-step treatment, was carried out at King Abdulaziz University Hospital, Riyadh between May 2017 and January 2018. The main outcomes included postoperative uncorrected distance visual acuity (UDVA), residual refraction (manifest refraction) and complications. Read More

Int Ophthalmol 2021 Jun 22;41(6):2091-2098. Epub 2021 Mar 22.

Department of Ophthalmology, Barzilai Medical Center, Ashkelon, Israel.

Purpose: To compare the refractive outcomes of laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) for myopic astigmatism of 3 diopters (D) or more.

Study Design: Retrospective matched comparative study.

Methods: This study include consecutive myopic patients (SE 0 to -10 D) undergoing LASIK or PRK between 2007 and 2016 with astigmatism of 3 to 6 D, and postoperative follow-up of at least 30 days for LASIK and 60 days for PRK, compared outcomes of LASIK and PRK eyes. Read More

Int J Ophthalmol 2021 18;14(3):423-429. Epub 2021 Mar 18.

Department of Ophthalmology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, China.

Aim: To compare the quality outcomes of vision at early phase after topography-guided femtosecond laser-assisted keratomileusis (FS-LASIK-CV) and small incision lenticule extraction (SMILE) in treatment of myopia and myopic astigmatism.

Methods: Retrospective comparative analysis of 49 patients that underwent FS-LASIK (=23) or SMILE (=26) procedure for myopia and myopic astigmatism between April and September in 2019. Pre- and postoperative uncorrected visual acuity (UCVA), spherical equivalent refraction (SEQ), cylindrical refraction, contrast sensitivity function (CSF), and corneal higher-order aberrations (HOAs) were evaluated. Read More

Clin Ophthalmol 2021 9;15:1073-1074. Epub 2021 Mar 9.

Ophthalmology Department, Kasr Alainy, Faculty of Medicine, Cairo University, Cairo, Egypt.

J Med Case Rep 2021 Mar 16;15(1):122. Epub 2021 Mar 16.

Takayanagi EYE Clinic, Sapporo S1 Building 3F, Nishi4-20-5, Minami1-jo, Chuo-ku, Sapporo, Hokkaido, 060-0807, Japan.

Background: Corneal refractive surgeries cause epithelial damage and induce wound healing processes. To promote wound healing after photorefractive keratectomy, the effectiveness of an autologous platelet tissue graft was assessed.

Case Presentation: A 45-year-old Asian male with low myopia and/or myopic astigmatism received photorefractive keratectomy in both eyes. Read More

Clin Ophthalmol 2021 1;15:889-890. Epub 2021 Mar 1.

Department of Ophthalmology and Visual Sciences, McGill University, Montreal, QC, Canada.

Exp Ther Med 2021 Mar 26;21(3):288. Epub 2021 Jan 26.

Department of Ophthalmology, Faculty of Medicine, 'Lucian Blaga' University, 550159 Sibiu, Romania.

The present study evaluated the efficacy, the safety and the predictability of the Femtosecond laser-assisted keratomileusis (Femto-LASIK) procedure for hyperopia and hyperopic astigmatism. We retrospectively analyzed the postoperative 12-month evolution of 593 eyes with hyperopia and hyperopic astigmatism that underwent Femto-LASIK treatment. The procedure was predictable and effective. Read More

Clin Ophthalmol 2021 10;15:491-493. Epub 2021 Feb 10.

Motwani LASIK Institute, San Diego, CA, 92121, USA.

BMC Ophthalmol 2021 Jan 9;21(1):23. Epub 2021 Jan 9.

Onnuri Eye Hospital, 325, Baekje-daero, Wansan-gu, Jeonju-si, Jeollabuk-do, Republic of Korea.

Background: To evaluate clinical outcomes after full-thickness astigmatic keratotomy (FTAK) combined with small-incision lenticule extraction (SMILE) in eyes with high astigmatism.

Methods: This study comprised 75 eyes of 43 patients with over 4.0 diopters (D) of astigmatism who were treated with SMILE after FTAK. Read More

Acta Inform Med 2020 Sep;28(3):180-184

Department of Ophthalmology, Rijeka University Hospital, Rijeka, Croatia.

Introduction: T Transepithelial photorefractive keratectomy (T-PRK) and femtosecond laser in situ keratomileusis (Fs-LASIK) are reftactive surgery methods for treating myopia and myopic astigmatism. Although T-PRK obtains similar results to Fs-LASIK with spherical myopia, it has differences in astigmatism correction. Vector analysis is a perfect tool to see the real difference between these two methods regarding astigmatic refraction and visual acuity. Read More

Clin Ophthalmol 2020 18;14:4423-4430. Epub 2020 Dec 18.

Ophthalmology Department, Benha College of Medicine, Benha University, Benha, Egypt.

Purpose: To assess the stability, safety, predictability, and efficacy of topography-guided myopic Femto-LASIK with two different treatment protocols.

Setting: Ebsar Eye center, Benha, Qalyopia, Egypt.

Design: Single-center, retrospective, COHORT control study. Read More

J Fr Ophtalmol 2021 Feb 25;44(2):189-195. Epub 2020 Dec 25.

CHNO des Quinze-Vingts, IHU Foresight, Inserm-DGOS CIC 1423, 28, rue de Charenton, 75012 Paris, France; Sorbonne Université, Inserm, CNRS, Institut de la Vision, 17, rue Moreau, 75012 Paris, France; Department of Ophthalmology, Ambroise Paré Hospital, AP-HP, University of Versailles Saint-Quentin-en-Yvelines, Boulogne-Billancourt, France.

Purpose: To determine whether manifest refractive astigmatism (RA) or anterior corneal astigmatism (CA) is the best value for excimer laser programming in cases of ocular residual astigmatism (ORA).

Patients And Methods: Patients who had undergone LASIK surgery with a disagreement between manifest refractive and corneal cylinder (ocular residual astigmatism ORA)>0.75 D were included retrospectively in this study. Read More

Cochrane Database Syst Rev 2020 12 18;12:CD012687. Epub 2020 Dec 18.

Department of Ophthalmology, University of Colorado Anschutz Medical Campus, Denver, Colorado, USA.

Background: Refractive errors (conditions in which the eye fails to focus objects accurately on the retina due to defects in the refractive system), are the most common cause of visual impairment. Myopia, hyperopia, and astigmatism are low-order aberrations, usually corrected with spectacles, contact lenses, or conventional refractive surgery. Higher-order aberrations (HOAs) can be quantified with wavefront aberration instruments and corrected using wavefront-guided or wavefront-optimized laser surgery. Read More

Clin Ophthalmol 2020 9;14:4337-4346. Epub 2020 Dec 9.

Hoopes Vision Research Center, Hoopes Vision, Draper, UT, USA.

Purpose: To report the outcomes of sequential posterior chamber phakic intraocular lens (PC-pIOL) with corneal refractive surgery in conventional (PC-pIOL prior to refractive surgery) and reverse (refractive surgery prior to PC-pIOL) bioptics for treating high myopic astigmatism.

Setting: Tertiary refractive center, Draper, Utah, USA.

Design: Retrospective case series. Read More

J Cataract Refract Surg 2020 Dec 9. Epub 2020 Dec 9.

Coleman Vision, Albuquerque, NM.

Purpose: To evaluate visual, refractive, aberrometric and patient-reported outcomes of wavefront-guided (WFG) myopic laser in situ keratomileusis (LASIK) using a high-resolution Hartmann-Shack aberrometer (iDesign Advanced WaveScan system, Johnson & Johnson Vision, Santa Ana, CA) with a new nomogram. The study was designed to determine if the new nomogram resolved the mild undercorrection that occurs with the manufacturer's default settings.

Setting: Three private LASIK practices. Read More

Eur J Ophthalmol 2020 Dec 14:1120672120980346. Epub 2020 Dec 14.

Assuta Optic Laser Center, Assuta Medical Center, Tel Aviv, Israel.

Introduction: The purpose of this study was to compare the outcomes of transepithelial photorefractive keratectomy (Trans-PRK) with femtosecond laser assisted in situ keratomileusis (FS-LASIK) for the correction of low to moderate myopia.

Methods: A retrospective cohort study design was used. The study group included patients with myopia less than -6. Read More

J Refract Surg 2020 Dec;36(12):844-850

Purpose: To determine the volumes altered during photorefractive keratectomy (PRK), laser in situ keratomileusis (LASIK), and small incision lenticule extraction (SMILE) correction of myopia and myopic astigmatism.

Methods: The volumes of stromal tissue affected by surgical correction of pure and astigmatic myopia were calculated in this theoretical study for PRK, LASIK, and SMILE treatments. These results were then used to calculate representative values for percent volume altered (PVA) restricted to stromal corneal tissue. Read More