49 results match your criteria Asteatotic Eczema


Diagnosis and Management of Dermatitis, Including Atopic, Contact, and Hand Eczemas.

Med Clin North Am 2021 Jul;105(4):611-626

Geisel School of Medicine at Dartmouth, Hanover, NH, USA; Department of Dermatology, Dartmouth-Hitchcock Medical Center, 18 Old Etna Road, Lebanon, NH 03766, USA.

This is a comprehensive and current guide for the diagnosis, differential diagnosis, treatment, and management of eczematous dermatitis, with a focus on atopic dermatitis, irritant and allergic contact dermatitis, hand dermatitis including recurrent vesicular and hyperkeratotic types, asteatotic dermatitis, and nummular or discoid dermatitis. Diagnostic options highlighted are clinical history, physical examination, and patch testing. Therapeutic options highlighted are moisturizers, topical corticosteroids, topical calcineurin inhibitors, crisaborole, phototherapy, and systemic medications including biologics. Read More

View Article and Full-Text PDF

Incidence of Adverse Cutaneous Reactions to Epidermal Growth Factor Receptor Inhibitors in Patients with Non-Small-Cell Lung Cancer.

Dermatology 2021 Jan 28:1-5. Epub 2021 Jan 28.

Section of Dermatology and Venereology, Department of Medicine, University of Verona, Verona, Italy.

Background: Epidermal growth factor receptor (EGFR) inhibitors are routinely used in advanced non-small-cell lung cancer (NSCLC) harboring EGFR mutations. However, their use is associated with gastrointestinal and cutaneous toxicities, including acneiform eruptions, pruritus, xerosis, nail and hair changes. Aside from reducing patients' quality of life, such cutaneous reactions have a considerable impact on the oncologic treatment given that dose reduction or even drug discontinuation may be necessary, especially for the severe forms. Read More

View Article and Full-Text PDF
January 2021

Prevalence of Cold Dermatoses in Kashmir Valley: A Cross-Sectional Study from North India.

Indian Dermatol Online J 2020 Sep-Oct;11(5):731-737. Epub 2020 Sep 19.

Department of Dermatology, STDs and Leprosy, Government Medical College, Srinagar, Jammu and Kashmir, India.

Background: Often quoted as "heaven on earth," Kashmir forms one of the two divisions of the Union territory of Jammu and Kashmir. A high-altitude region with abundant precipitation and snowfall, the people of Kashmir experience peculiar dermatoses not commonly seen in the majorly tropical subcontinent of India. In this study, we focussed on cold dermatoses as a comprehensive cluster and attempted to study them as a group. Read More

View Article and Full-Text PDF
September 2020

The High Prevalence of Skin Diseases in Adults Aged 70 and Older.

J Am Geriatr Soc 2020 11 4;68(11):2565-2571. Epub 2020 Aug 4.

Department of Dermatology, University Hospital of Oulu, Oulu, Finland.

Background/objectives: To determine the prevalence of skin findings and skin diseases in adults aged 70 and older, and to study the association between cutaneous diseases and socioeconomic status (SES), sex, and living status in the older population.

Design: Cross-sectional study of Finnish adults aged 70 to 93 as part of the Northern Finland Birth Cohort 1966 Study.

Settings: Skin examination data were available for 552 adults. Read More

View Article and Full-Text PDF
November 2020

Cannabinoids for the treatment of chronic pruritus: A review.

J Am Acad Dermatol 2020 May 25;82(5):1205-1212. Epub 2020 Jan 25.

Division of Dermatology, The Ohio State University Wexner Medical Center, Columbus, Ohio. Electronic address:

Medical marijuana is becoming widely available to patients in the United States, and with recreational marijuana now legalized in many states, patient interest is on the rise. The endocannabinoid system plays an important role in skin homeostasis in addition to broader effects on neurogenic responses such as pruritus and nociception, inflammation, and immune reactions. Numerous studies of in vitro and animal models have provided insight into the possible mechanisms of cannabinoid modulation on pruritus, with the most evidence behind neuronal modulation of peripheral itch fibers and centrally acting cannabinoid receptors. Read More

View Article and Full-Text PDF

Bioactive: A new era of bioactive ingredients in topical formulations for inflammatory dermatoses.

Dermatol Ther 2019 11 11;32(6):e13101. Epub 2019 Oct 11.

Department of Medicine, Division of Dermatology, University of Arizona, Tucson, Arizona.

Moisturization is the pillar of daily skin care and has significant benefit in improving hydration, strengthening the skin barrier, and ameliorating inflammatory dermatoses. Bioactive ingredients such as endocannabinoids, bioactive lipids, growth factors, microbiome modulators, and antioxidant enzymes are increasingly being incorporated into moisturizer formulations. These novel ingredients have been shown to improve skin barrier function, upregulate barrier lipid synthesis, decrease itch and inflammation, and have antioxidative properties. Read More

View Article and Full-Text PDF
November 2019

Itching and its related factors in subtypes of eczema: a cross-sectional multicenter study in tertiary hospitals of China.

Sci Rep 2018 Jul 17;8(1):10754. Epub 2018 Jul 17.

Department of Dermatology, Beijing Shijitan Hospital, Capital Medical University, 10 Tie Yi Road, Haidian District, Beijing, 100038, China.

Itching is a leading symptom of eczema or dermatitis and has a great impact on patients' lives. Previous studies on itching have focused mostly on atopic dermatitis (AD). A cross-sectional multicenter study was conducted among outpatients with eczema from 39 tertiary hospitals in mainland China from July 1 to September 30, 2014. Read More

View Article and Full-Text PDF

The Endocannabinoid System and Its Role in Eczematous Dermatoses.

Dermatitis 2017 Jan/Feb;28(1):22-32

From the *Drexel University College of Medicine, Philadelphia, PA; †School of Medicine, ‡Department of Dermatology, University of California, Davis; and §Dermatology Division, Department of Medicine, University of Arizona, Tucson.

The skin serves as the foremost barrier between the internal body and the external world, providing crucial protection against pathogens and chemical, mechanical, and ultraviolet damages. The skin is a central player in the intricate network of immune, neurologic, and endocrine systems. The endocannabinoid system (ECS) includes an extensive network of bioactive lipid mediators and their receptors, functions to modulate appetite, pain, mood, and memory, and has recently been implicated in skin homeostasis. Read More

View Article and Full-Text PDF

Generalized eczema craquelé (asteatotic dermatitis) associated with pemetrexed treatment.

J Eur Acad Dermatol Venereol 2016 Oct 28;30(10):e81-e83. Epub 2015 Sep 28.

Department of Dermatology, Cathay General Hospital, Taipei, Taiwan.

View Article and Full-Text PDF
October 2016

[Asteatotic eczema as paraneoplastic syndrome].

Ned Tijdschr Geneeskd 2016;160:D391

Franciscus Gasthuis & Vlietland, locatie Gasthuis, Rotterdam.

Background: Asteatotic eczema is rarely associated with an underlying malignancy. The condition as paraneoplastic syndrome is characterised by glucocorticoid resistance.

Case Description: A 66-year old woman came to the emergency room with symptoms of dehydration resulting from diarrhoea due to cyclosporine therapy for treatment-resistant eczema. Read More

View Article and Full-Text PDF
February 2018

Eczema craquelé associated with nephrotic syndrome.

JAAD Case Rep 2016 May 24;2(3):241-3. Epub 2016 Jun 24.

Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut.

View Article and Full-Text PDF

Dermatological Complaints of the Elderly Attending a Dermatology Outpatient Clinic in Turkey: A Prospective Study over a One-year Period.

Acta Dermatovenerol Croat 2015 ;23(4):277-81

Assoc. Prof. Muhterem Polat, MD, Gazi University School of Medicine, Department of Dermatology, Ankara, Turkey;

The geriatric population is continuously growing, which leads to more aged patients being admitted to dermatology clinics. The aim of this study is to determine the dermatological complaints of the elderly attending a dermatology outpatient clinic. All of the patients aged 65 years and older admitted to our dermatology outpatient clinic over a 1-year period were included. Read More

View Article and Full-Text PDF
February 2017

[Adult kwashiorkor: a rare complication of bariatric surgery].

Ann Dermatol Venereol 2015 Feb 30;142(2):99-103. Epub 2014 Dec 30.

Service de dermatologie, CHU de Poitiers, 2, rue de la Milétrie 86021 Poitiers cedex, France.

Introduction: Kwashiorkor is a clinical manifestation of global protein-calorie malnutrition that is described mainly in children in developing countries initially presenting eczema-like skin disease associated with hydrops.

Observation: We report the case of a 44-year-old woman with dark skin who had undergone bariatric surgery for treatment of stage-III obesity without regular monitoring and who was hospitalized in our dermatology department four years later. She had diffuse oedema and asteatotic eczema-like cutaneous lesions on pigmented skin that had developed for two months despite daily application of topical corticosteroids. Read More

View Article and Full-Text PDF
February 2015

[The Dutch College of General Practitioners practice guideline 'Eczema'].

Ned Tijdschr Geneeskd 2014 ;158:A8009

*Namens de werkgroep NHG-standaard 'Eczeem', waarvan de leden aan het eind van dit artikel staan vermeld.

The Dutch College of General Practitioners practice guideline 'Eczema' provides recommendations for the diagnosis and treatment of common types of eczema: atopic dermatitis, contact dermatitis, acro-vesicular eczema, nummular eczema, hypostatic eczema, and asteatotic eczema. Age is an important factor when determining the type of eczema. According to the guideline, patient history and physical examination are sufficient in the diagnosis of eczema; additional investigations are rarely indicated. Read More

View Article and Full-Text PDF

N-palmitoylethanolamine and N-acetylethanolamine are effective in asteatotic eczema: results of a randomized, double-blind, controlled study in 60 patients.

Clin Interv Aging 2014 17;9:1163-9. Epub 2014 Jul 17.

Research and Studies Center on the Integument, Department of Dermatology, Besançon University Hospital, University of Franche-Comté, Franche-Comté, France.

Background: Asteatotic eczema (AE) is characterized by itchy, dry, rough, and scaling skin. The treatments for AE are mainly emollients, usually containing urea, lactic acid, or a lactate salt. N-palmitoylethanolamine (PEA) and N-acetylethanolamine (AEA) are both endogenous lipids used as novel therapeutic tools in the treatment of many skin diseases. Read More

View Article and Full-Text PDF

Asteatotic eczema in hypoesthetic skin: a case series.

JAMA Dermatol 2014 Oct;150(10):1088-90

Department of Dermatology, Walter Reed National Military Medical Center, Bethesda, Maryland.

Importance: Asteatotic eczema (eczema craquelé, xerotic eczema) occurs most frequently in areas of dehydrated skin, most often during the winter months when decreased humidity results in increased water loss from the stratum corneum. We present 5 cases in which asteatotic eczema was found outside of its normal distribution, within desensitized skin and scars.

Observations: Five patients with a history of trauma and scar formation presented with erythematous, dry plaques with fine crackling involving hypoesthetic skin. Read More

View Article and Full-Text PDF
October 2014

Pruritus of unknown origin and elevated total serum bile acid levels in patients without clinically apparent liver disease.

J Gastroenterol Hepatol 2011 Apr;26(4):716-21

Department of Dermatology and Venerology, Medical University Innsbruck, Innsbruck, Austria.

Background And Aim: Generalized pruritus of unknown origin (PUO) is a highly distressing condition that is unrelated to any underlying dermatologic or systemic disorder (e.g. cholestasis). Read More

View Article and Full-Text PDF

Primary cutaneous nodular amyloidosis initially presenting with eczema.

Authors:
E Y Gan H L Tey

Singapore Med J 2010 Sep;51(9):e158-60

National Skin Centre, 1 Mandalay Road, Singapore 308205.

We report an unusual case of a 76-year-old woman with primary cutaneous amyloidosis who initially presented with features of asteatotic eczema that was unresponsive to topical corticosteroid treatment. Histological examination revealed amyloid deposits involving the superficial and deep dermis. These lesions later gradually evolved into erythematous nodules, and a second biopsy performed 29 months after the initial presentation again revealed diffuse collections of amyloid throughout the dermis. Read More

View Article and Full-Text PDF
September 2010

Skin barrier breakdown: a renaissance in emollient therapy.

Br J Nurs 2009 Jul 23-Aug 12;18(14):872, 874, 876-7

Sheffield Children's Hospital and Sheffield Teaching Hospitals, and School of Medicine and Biomedical Sciences, The University of Sheffield, Sheffield.

Breakdown of the skin barrier is the first event in the development of atopic eczema (atopic dermatitis). Research over the past five years has indicated that this arises as a result of the interaction of environmental agents such as soap and other detergents with the products of changes in several genes. These genetic changes predispose to the breakdown of the skin barrier, which allows the penetration of allergens, triggering a flare of atopic eczema. Read More

View Article and Full-Text PDF
September 2009

Patterns of lower leg and foot eczema in South India.

Indian J Dermatol Venereol Leprol 2008 Sep-Oct;74(5):458-61

Department of Dermatology and STD, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, India.

Background: The pattern of eczema is altered by geography, habits of people and environmental factors and regional variation in skin structure and function.

Aims: Our study was done to estimate frequency and patterns of lower leg and foot eczemas.

Methods: A total of 200 patients with various types of lower leg and foot eczemas were recruited over a period of 2 years. Read More

View Article and Full-Text PDF

Use of pimecrolimus cream in disorders other than atopic dermatitis.

J Cutan Med Surg 2008 Jan-Feb;12(1):17-26

Division of Dermatology and Cutaneous Sciences, University of Alberta, Edmonton, AB, Canada.

Background: Pimecrolimus is indicated for treatment of atopic dermatitis and has been evaluated in many other disorders.

Objective: To review the efficacy of pimecrolimus in treatment of disorders other than atopic dermatitis.

Methods: We performed a PubMed search of the English-language literature using the key word "pimecrolimus. Read More

View Article and Full-Text PDF

Implant infection caused by dermatitis: a report of two cases.

J Orthop Surg (Hong Kong) 2007 Dec;15(3):365-7

Department of Orthopaedic Surgery, National University Hospital, Singapore.

We report 2 cases of implant infection with Staphylococcus aureus associated with dermatitis. In both cases, the skin at the surgical site was normal and full antiseptic measures were taken. One patient had a history of chronic asteatotic eczema complicated by cellulitis; the other had generalised exfoliative dermatitis with an atopic aetiology. Read More

View Article and Full-Text PDF
December 2007

The role of topical calcineurin inhibitors for skin diseases other than atopic dermatitis.

Authors:
Uwe Wollina

Am J Clin Dermatol 2007 ;8(3):157-73

Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Dresden, Germany.

The topical calcineurin inhibitors (TCIs) pimecrolimus and tacrolimus are approved for atopic dermatitis but have additional potential in other inflammatory skin diseases. This article reviews their clinical use in non-atopic dermatitis diseases. In seborrheic dermatitis, asteatotic eczema, and contact dermatitis, TCIs are of great benefit and can compete with topical corticosteroids. Read More

View Article and Full-Text PDF

Pimecrolimus cream 1% is effective in asteatotic eczema: results of a randomized, double-blind, vehicle-controlled study in 40 patients.

J Eur Acad Dermatol Venereol 2007 Jan;21(1):90-4

Department of Dermatology, University Clinics Münster, Münster, Germany.

Background And Objective: Pimecrolimus cream 1% is an effective treatment for atopic eczema. The aim was to investigate its efficacy in asteatotic eczema, a skin disease similar to atopic eczema and its associated dry skin and itching.

Methods: Single-centre, randomized, double-blind, vehicle controlled study in 40 patients with asteatotic eczema. Read More

View Article and Full-Text PDF
January 2007