477,483 results match your criteria Assisted Living Consult [Journal]
Methods Mol Biol 2019 ;1894:247-269
Department of Anatomical Sciences and Neurobiology, University of Louisville, Louisville, KY, USA.
In this chapter, we highlight the applications of electron microscopes (EMs) in nanotoxicity assessment. EMs can provide detailed information about the size and morphology of nanomaterials (NMs), their localization in cells and tissues, the nano-bio interactions, as well as the ultrastructural changes induced by NMs exposure. Here, we share with the readers how we prepare the tissue sample, and the different types of EMs used among the nanotoxicologists. Read More
Lasers Med Sci 2018 Dec 13. Epub 2018 Dec 13.
National Engineering Laboratory for Animal Breeding and Key Laboratory of Animal Genetics, Breeding and Reproduction, Beijing Key Laboratory for Animal Genetic Improvement, College of Animal Science and Technology, China Agricultural University, Beijing, China.
Embryo vitrification has advantages in assisted reproduction yet it also induces zona hardening. Laser zona thinning (LZT) is considered as a solution yet its efficacy and security have not been well studied. In this study, we used vitrified-warmed morulae from 2-month-old and 10-month-old ICR female mice as model to investigate the impacts that LZT treatment brings to the in vitro hatching process and implantation by analyzing hatching rate, implantation rate, and blastocyst quality. Read More
Eur Radiol 2018 Dec 13. Epub 2018 Dec 13.
Advanced Medical Device Research Division, Korea Electrotechnology Research Institute, 111 Hanggaul-ro, Sangnok-gu, Ansan-si, Gyeonggi-do, 15588, Republic of Korea.
Objectives: To compare the diagnostic performance and interpretation time of digital breast tomosynthesis (DBT) for both novice and experienced readers with and without using a computer-aided detection (CAD) system for concurrent read.
Methods: CAD system was developed for concurrent read in DBT interpretation. In this observer performance study, we used an enriched sample of 100 DBT cases including 70 with and 30 without breast cancers. Read More
World J Urol 2018 Dec 13. Epub 2018 Dec 13.
Department of Urology, Uro-Oncology, Robot Assisted and Reconstructive Urologic Surgery, University Hospital Cologne, Kerpener Straße 62, 50937, Cologne, Germany.
Purpose: To identify potential risk factors for the development of venous thromboembolic events in testicular cancer patients receiving platinum-based chemotherapy.
Methods: We performed a retrospective analysis including 255 patients with testicular germ cell tumors who received platinum-based chemotherapy from 2003 to 2018 as a multi-center observational cohort study. Patient and tumor characteristics of patients with and without a thromboembolic event were analyzed. Read More
J Spine Surg 2018 Sep;4(3):681-683
Department of Pathology, Queen Elizabeth Hospital, Hong Kong, China.
J Spine Surg 2018 Sep;4(3):645-653
Department of Spine Surgery, Digital Orthopedic Institute, Orthopedic Hospital, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Second Medical College of Wenzhou Medical University, Zhejiang Spine Surgery Center, Wenzhou 325027, China.
Rapid development of 3D printing techniques has led to the design of navigation templates to assist with accurate insertion of pedicle screws in last decades. However, there are still without the precise step-by-step methods to design 3D navigation templates from computed tomography (CT) images. Our present article provides a detailed protocol to allow the readers or researchers to obtain the 3D navigation template easily, and assist with pedicle screw insertion in their future research and surgery. Read More
IEEE Robot Autom Lett 2019 Jan 19;4(1):145-152. Epub 2018 Nov 19.
Department of Electrical Engineering and Computer Science, Case Western Reserve University, Cleveland, OH.
Robot-assisted medical interventions, such as robotic catheter ablation, often require the robot to perform tasks on a tissue surface. This paper presents a task-space motion planning method that generates actuation trajectories which steer the end- effector of the MRI-actuated robot along desired trajectories on the surface. The continuum robot is modeled using the pseudo-rigid-body model, where the continuum body of the robot is approximated by rigid links joined by flexible joints. Read More
Eur J Radiol Open 2019 5;6:1-8. Epub 2018 Dec 5.
Dept of Surgery and Urology, Danderyd University Hospital, Stockholm, Sweden.
Background: Ablation therapies for tumours are becoming more used as ablation modalities evolve and targeting solutions are getting better. There is an increasing body of long-term results challenging resection and proving lower morbidities and costs. The aim of this paper is to share the experiences from a high-volume centre in introducing computer assisted targeting solutions and efficient ablation modalities like microwave generators and irreversible electroporation. Read More
Obere Extrem 2018 7;13(4):269-272. Epub 2018 Nov 7.
Department of Orthopedic Surgery, Mayo Clinic, 200 First Street SW, 55905 Rochester, MN USA.
Lower trapezius tendon transfer with Achilles tendon allograft augmentation may be used to treat patients with lack of active external rotation following shoulder paralysis or massive irreparable posterosuperior rotator cuff tears. In the setting of shoulder paralysis, the integrity of the ipsilateral lower trapezius may be compromised. In this instance, the contralateral lower trapezius may be used with reasonable results. Read More
JMIR Ment Health 2018 Dec 13;5(4):e64. Epub 2018 Dec 13.
X2AI Inc, San Francisco, CA, United States.
Background: Students in need of mental health care face many barriers including cost, location, availability, and stigma. Studies show that computer-assisted therapy and 1 conversational chatbot delivering cognitive behavioral therapy (CBT) offer a less-intensive and more cost-effective alternative for treating depression and anxiety. Although CBT is one of the most effective treatment methods, applying an integrative approach has been linked to equally effective posttreatment improvement. Read More
Reprod Biomed Online 2018 Nov 20. Epub 2018 Nov 20.
Assisted Conception Unit, Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, 1E, Special Block, Prince of Wales Hospital, Ngan Shing Street, Hong Kong. Electronic address:
Research Question: Do spermatozoa with different sex chromosome complements (X and Y; aneuploidy and monosomy) exhibit different degrees of DNA damage?
Design: A prospective, observational study to measure the DNA fragmentation level and sex chromosome complement simultaneously using combined sperm chromosome dispersion (SCD) and fluorescence in-situ hybridization tests. Two methods were used to evaluate SCD images: a traditional semi-quantitative method to categorize halo size and a newly developed quantitative method based on the Matlab image analysis programme to more precisely measure the halo area and calculate the halo size index (HSI).
Results: The HSI (which was inversely proportional to DNA fragmentation level) of Y chromosome-bearing spermatozoa was significantly (P < 0. Read More
Comput Biol Chem 2018 Dec 3. Epub 2018 Dec 3.
College of Life Sciences, Shaanxi Normal University, Xi'an, 710119, China; National Engineering Laboratory for Resource Developing of Endangered Chinese Crude Drugs in Northwest of China. Electronic address:
The development of efficient and convenient strategy without involving enzyme or complex nanomaterial for the micro molecules detection has profound meaning in the diagnosis of diseases. Herein, taking the advantages of the strong affinity of aptamer and catalyzed hairpin assembly, we develop a new non-label optical amplified strategy for thrombin detection in this work. To support both biological inquiry and technological innovation, thermodynamic models are introduced to predict the minimum energy secondary structure of interacting nucleic acid strands and calculate the partition function and equilibrium concentration for complexes in our system. Read More
J Ayurveda Integr Med 2018 Dec 10. Epub 2018 Dec 10.
Institute of Ayurveda and Integrative Medicine, Trans Disciplinary University, No.74/2, Jarakabandekaval Post Attur, Via Yelahanka, Bangalore, 560 064, Karnataka, India.
Non-healing diabetic foot has always demanded more attention from the surgeon due to the distinct problem it possesses. There is a constant need for the evolvement in the management and this case is one such attempt. A 62-year-old male patient with a history of diabetes mellitus since 10 years presented with a non-healing foot ulcer since 1 month. Read More
J Stroke Cerebrovasc Dis 2018 Dec 10. Epub 2018 Dec 10.
Department of Neurology, Pomeranian Medical University, Szczecin, Poland. Electronic address:
Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) is a genetically determined disease of the cerebral vessels, characterized by recurrent ischemic strokes, dementia, and degeneration of the cerebral white matter. The condition is caused by a mutation in the NOTCH3 gene, whose product plays a great role in the development and physiology of the cardiovascular system. Magnetic resonance imaging reveals multiple hyperintensive lesions of the white matter in the T2-weighted images also in asymptomatic carriers of CADASIL and can be detected even 10-15 years prior to clinical signs. Read More
Acad Radiol 2018 Dec 10. Epub 2018 Dec 10.
Cancer Epidemiology Department, Moffitt Cancer Center & Research Institute, 12902 Bruce B Downs Blvd, Mail Stop: MRC Can/Cont, Tampa, FL 33612. Electronic address:
Rationale And Objectives: Mammographic density is an important risk factor for breast cancer, but translation to the clinic requires assurance that prior work based on mammography is applicable to current technologies. The purpose of this work is to evaluate whether a calibration methodology developed previously produces breast density metrics predictive of breast cancer risk when applied to a case-control study.
Materials And Methods: A matched case control study (n = 319 pairs) was used to evaluate two calibrated measures of breast density. Read More
Taiwan J Obstet Gynecol 2018 Dec;57(6):810-813
Reasearch and Clinical Center for Infertility, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Electronic address:
Objective: One of the important aspects involved in achieving optimal outcomes after assisted reproductive treatment (ART) is the endometrium. Some cycles are cancelled due to inadequate endometrial growth in ART. In this clinical trial, we evaluated the effectiveness of platelet-rich plasma (PRP) in the treatment of thin endometrium. Read More
Addict Sci Clin Pract 2018 Dec 13;13(1):25. Epub 2018 Dec 13.
Center for Innovation to Implementation, Palo Alto Health Care System, 795 Willow Rd, MC152, Palo Alto, CA, 94304, USA.
Background: In the US, emergency room visits and overdoses related to prescription opioids have soared and the rates of illicit opioid use, including heroin and fentanyl, are increasing. Opioid use disorder (OUD) is associated with higher morbidity and mortality, higher HIV and HCV infection rates, and criminal behavior. Opioid agonist therapy (OAT; methadone and buprenorphine) is proven to be effective in treating OUD and decreasing its negative consequences. Read More
Int J Mol Sci 2018 Dec 12;19(12). Epub 2018 Dec 12.
College of Horticulture, Nanjing Agricultural University, Nanjing 210095, China.
Salinity is ubiquitous abiotic stress factor limiting viticulture productivity worldwide. However, the grapevine is vulnerable to salt stress, which severely affects growth and development of the vine. Hence, it is crucial to delve into the salt resistance mechanism and screen out salt-resistance prediction marker genes; we implicated RNA-sequence (RNA-seq) technology to compare the grapevine transcriptome profile to salt stress. Read More
Int J Mol Sci 2018 Dec 12;19(12). Epub 2018 Dec 12.
Laboratory of Reproductive Biology, Institute of Biotechnology CAS, v.v.i., BIOCEV, Prumyslova 595, 252 50 Vestec, Czech Republic.
17β-estradiol (estradiol) is a natural estrogen regulating reproduction including sperm and egg development, sperm maturation-called capacitation-and sperm⁻egg communication. High doses can increase germ cell apoptosis and decrease sperm count. Our aim was to answer the biological relevance of estradiol in sperm capacitation and its effect on motility and acrosome reaction to quantify its interaction with estrogen receptors and propose a model of estradiol action during capacitation using kinetic analysis. Read More
Nanomaterials (Basel) 2018 Dec 12;8(12). Epub 2018 Dec 12.
Bejing Key Laboratory of Quantum Devices, Key Laboratory for the Physics and Chemistry of Nanodevices, and Department of Electronics, Peking University, Beijing 100871, China.
It is difficult to obtain γ-Fe₂O₃ nanostructures by heating iron substrate in ambient conditions because γ-Fe₂O₃ is less thermodynamically stable than α-Fe₂O₃. In this work, we synthesize γ-Fe₂O₃ nanowires by heating iron particles under an external force. The stacking style of iron and oxygen ions under a strong shearing stress tends to adopt the γ-Fe₂O₃ structure regardless of the thermodynamic restriction. Read More
Int J Environ Res Public Health 2018 Dec 12;15(12). Epub 2018 Dec 12.
Department of Organization and Consumption Economics, Faculty of Human Nutrition and Consumer Sciences, Warsaw University of Life Sciences (SGGW-WULS), 159C Nowoursynowska Street, 02-787 Warsaw, Poland.
Insufficient fruit intake is observed worldwide despite the generally higher preference for consumption of fruits than vegetables. For children, the determinants of consumption, such as at-home accessibility and parental consumption patterns, may especially influence fruit intake. The aim of this study was to analyze the association between fruit consumption behaviors and the preferences of mothers and their declared behaviors and preferences of children. Read More
Molecules 2018 Dec 11;23(12). Epub 2018 Dec 11.
School of Pharmacy, Zunyi Medical University, Zunyi 563003, China.
As a new and green solvent, ionic liquids (ILs) have received more attention during the green extraction and separation process for natural medicines. In this paper, IL-ultrasound-assisted extraction (IL-UAE) of total biflavonoids (TBFs) from was firstly developed, and different ILs were employed and compared. Based on single-factor experiment, solid⁻liquid ratio (1:10⁻1:14 g/mL), IL concentration (0. Read More
Materials (Basel) 2018 Dec 11;11(12). Epub 2018 Dec 11.
Centrum vyzkumu Rez (CVR), Rez 130, 250 68 Husinec, Czech Republic.
The environmental performance of structural materials (e.g., corrosion and environmental assisted cracking) is one of the critical issues being addressed in the development of Generation IV fast reactors. Read More
Materials (Basel) 2018 Dec 11;11(12). Epub 2018 Dec 11.
Optical Nanoprocessing Lab, Department of Mechanical Engineering, Hanyang University, 55 Hanyangdaehak-ro, Sangnok-gu, Ansan, Gyeonggi-do 15588, Korea.
Selective laser sintering of metal nanoparticle ink is an attractive technology for the creation of metal layers at the microscale without any vacuum deposition process, yet its application to elastomer substrates has remained a highly challenging task. To address this issue, we introduced the shear-assisted laser transfer of metal nanoparticle ink by utilizing the difference in thermal expansion coefficients between the elastomer and the target metal electrode. The laser was focused and scanned across the absorbing metal nanoparticle ink layer that was in conformal contact with the elastomer with a high thermal expansion coefficient. Read More
Int J Mol Sci 2018 Dec 11;19(12). Epub 2018 Dec 11.
Department of Chemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
Hydrogen sulfide (H₂S) has emerged as an important signaling molecule and plays a significant role during different environmental stresses in plants. The present work was carried out to explore the potential role of H₂S in reversal of dehydration stress-inhibited -acetylserine (thiol) lyase (OAS-TL), l-cysteine desulfhydrase (LCD), and d-cysteine desulfhydrase (DCD) response in arugula ( Mill.) plants. Read More
Int J Environ Res Public Health 2018 Dec 9;15(12). Epub 2018 Dec 9.
School of Gerontology Health Management, College of Nursing, Taipei Medical University, Taipei 11031, Taiwan.
This study assesses the functioning and disability related to Parkinson's disease using the Functioning Disability Evaluation Scale-Adult Version (FUNDES-Adult), based on the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) in a large-scale database; this study describes, discusses and clarifies the predictive factor of not being in an ambulatory status. Read More
Sensors (Basel) 2018 Dec 8;18(12). Epub 2018 Dec 8.
School of Mechanical Engineering, Beijing Institute of Technology, Beijing 100081, China.
Crack assessment when making fitness-for-service decisions requires a thorough examination of crack location and size in critical areas. An ultrasonic transducer is used for such assessments, but traditional methods cannot cope with complex rotators, such as wheel hubs. We present a model of robot-assisted crack growth assessment in wheel hubs. Read More
Molecules 2018 Dec 10;23(12). Epub 2018 Dec 10.
LAQV/REQUIMTE, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal.
A recurrent problem faced by the pharmaceutical industry when formulating drug products concerns poorly soluble drugs, which, despite having desirable pharmacological activity, present limited bioavailability. Cocrystallization is growing up as a possible approach to tackle this problem. Cocrystals are crystalline materials comprising at least two components, solid at room temperature, and held together by non-covalent bonds. Read More
Toxins (Basel) 2018 Dec 10;10(12). Epub 2018 Dec 10.
Laboratory of Aquatic Product Processing and Quality Safety, Marine Fisheries Research Institute of Zhejiang, Zhoushan 316100, China.
Tetrodotoxin (TTX) is a marine biotoxin that has high scientific value. However, the lack of efficient TTX extraction and preparation methods has led to a scarcity of TTX samples for clinical application. In this study, TTX from the liver of was ultrasound-assisted extracted with acidified organic solvents. Read More
Molecules 2018 Dec 7;23(12). Epub 2018 Dec 7.
Regional Centre of Advanced Technologies and Materials, Department of Analytical Chemistry, Faculty of Science, Palacký University, 17. listopadu 12, 779 00 Olomouc, Czech Republic.
In this study, a soil from two ceramic vessels belonging to Corded Ware culture, 2707⁻2571 B.C., found in a cremation grave discovered in Central Moravia, Czech Republic, was analyzed using matrix-assisted laser desorption/ionization⁻mass spectrometry (MALDI⁻MS) combined with advanced statistical treatment (principal component analysis, PCA, and orthogonal projection to latent structures discriminant analysis, OPLS-DA) and by enzyme-linked immunosorbent assay (ELISA). Read More
Medicine (Baltimore) 2018 Dec;97(49):e13493
Center for Reproductive Medicine.
Genetic abnormalities could account for 10% to 15% of male infertility cases, so increasing attention is being paid to gene mutations in this context. DNAH1 gene polymorphisms are highly correlated with astheno-teratozoospermia, but limited information has been reported on pathogenic variations in DNAH1 in the Chinese population. We explored 4 novel variations of the DNAH1 gene in Chinese infertile patients. Read More
Medicine (Baltimore) 2018 Dec;97(49):e13474
Department of Urology, Institute of Urology, West China Hospital, Sichuan University.
Rationale: Inflammatory myofibroblastic tumors of the urinary bladder (IMTUB) is exceptionally rare. Currently, no standardized treatment has been established for IMTUBs.
Patient Concerns: Herein we report three cases presenting with hematuria and anemia. Read More
Medicine (Baltimore) 2018 Dec;97(49):e13331
Department of Orthopaedic Surgery, The Affiliated Hospital of Medical School, Ningbo University.
Background: Percutaneous screw fixation can provide stable fixation with a minimally invasive surgical technique for posterior talar process fracture.
Objectives: The purpose of this study was to investigate the optimal posterior screw placement and the geometry of safe zone for screw insertion in the posterior talar process by analyzing with 3-dimensional (3D) technology.
Methods: 100 adult feet computed tomography (CT) scans were evaluated. Read More
Medicine (Baltimore) 2018 Dec;97(49):e13316
Department of Orthopaedics.
Rationale: The purpose of this study was to estimate the efficacy and safety of percutaneous periacetabular screw (PPS) insertion assisted by screw view model of navigation (SVMN) to treat fracture of acetabulum.
Patient Concerns: A 61-year-old male patient was injured in a motorcycle accident, which caused pain, swelling, deformity and limited mobility on his right hip.
Diagnoses: He was diagnosed with fracture of acetabulum. Read More
Medicine (Baltimore) 2018 Dec;97(49):e13170
Department of Anesthesiology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine.
The ETView tracheoscopic ventilation tube (TVT) is a tracheal tube (TT) incorporating a video camera and a light source in its tip. The view from the tip appears continuously on a portable monitor in the anesthesia area. We evaluated the effectiveness and usefulness of the single/double ETView TVT in monitoring the tracheal tube position during general anesthesia undergoing video-assisted thoracoscopic lobectomy. Read More
J Neurosurg Spine 2018 Nov 1:1-7. Epub 2018 Nov 1.
OBJECTIVEIntravertebral augmentation (IVA) is a reliable minimally invasive technique for treating Magerl type A vertebral body fractures. However, poor correction of kyphotic angulation, the risk of cement leakage, and significant exposure to radiation (for the surgeon, the operating room staff, and the patient) remain significant issues. The authors conducted a study to assess the value of robot-assisted IVA (RA-IVA) for thoracolumbar vertebral body fractures. Read More
J Neurosurg Pediatr 2018 Dec 1:1-9. Epub 2018 Dec 1.
OBJECTIVEThe goal in the study was to describe the clinical outcomes associated with robot-assisted stereoelectroencephalography (SEEG) in children.METHODSThe authors performed a retrospective, single-center study in consecutive children with medically refractory epilepsy who were undergoing robot-assisted SEEG. Kaplan-Meier survival analysis was used to calculate the probability of seizure freedom. Read More
Eur J Public Health 2018 Dec 12. Epub 2018 Dec 12.
Department of Psychiatry, IIS-Jimenez Diaz Foundation, Madrid, Spain.
Background: There is little empirical research on the potential benefit that electronic patient portals (EPP) can have on the care quality and health outcomes of diverse multi-ethnic international populations. The purpose of this study is to determine the extent to which an EPP was associated with improvements in health service use.
Methods: Using a quasi-experimental interrupted time-series approach, we assessed health service use before (April 2012-September 2015) and after (October 2015-December 2016) the implementation of a comprehensive EPP at four hospitals in Madrid, Spain. Read More
Am J Nephrol 2018 Dec 13;49(1):11-19. Epub 2018 Dec 13.
Division of Nephrology, Department of Medicine, University of Alabama at, Birmingham, Alabama, USA.
Background: Despite national vascular access guidelines promoting the use of arteriovenous fistulas (AVF) over arteriovenous grafts (AVGs) for dialysis, AVF use is substantially lower in females. We assessed clinically relevant AVF and AVG surgical outcomes in elderly male and female patients initiating hemodialysis with a central venous catheter (CVC).
Methods: Using the United States Renal Data System standard analytic files linked with Medicare claims, we assessed incident hemodialysis patients in the United States, 9,458 elderly patients (≥67 years; 4,927 males and 4,531 females) initiating hemodialysis from July 2010 to June 2011 with a catheter and had an AVF or AVG placed within 6 months. Read More
Photodiagnosis Photodyn Ther 2018 Dec 10. Epub 2018 Dec 10.
Univ. Lille, INSERM, CHU Lille, U1189, ONCO-THAI, Image-Assisted Laser Therapy for Oncology, F-59000, Lille, France; Department of Neurosurgery, University Hospital, F-59000, Lille, France.
Background: There is currently no therapy that prevents high-grade glioma recurrence. Thus, these primary brain tumors have unfavorable outcomes. Recently, 5-ALA photodynamic therapy (PDT) has been proposed to delay relapse and is highly expected to have potential synergistic effects with the current standard of care. Read More
Int J Biol Macromol 2018 Dec 10. Epub 2018 Dec 10.
Bioprocessing and Biodetection Laboratory, Department of Food Science and Engineering, University of Tehran, Karaj 31587-77871, Iran.
In this work, a Box-Behnken design (BBD) with three variables (ultrasound power, irradiation time and pH) in three levels was applied for pectin extraction optimization. The optimization process showed that the maximum extraction yield was 28.07 ± 0. Read More
Int J Periodontics Restorative Dent 2019 Jan/Feb;39(1):39-47
The computer-assisted design/computer-assisted manufactured compound prosthesis involves designing and milling a cement-retained prosthesis over milled titanium bars. In the presented clinical case report, a diagnostic wax pattern was made to assess esthetics, contours, and occlusion. A total of eight maxillary root-form implants were restored by following the combined prosthesis design concept. Read More
Innovations (Phila) 2018 Nov/Dec;13(6):391-403
Division of Thoracic Surgery, Robert Tucker Hayes Foundation, University of Texas Southwestern Medical Center, Dallas, TX USA.
Great advances have been made in the surgical management of esophageal disease since the first description of esophageal resection in 1913. We are in the era of minimally invasive esophagectomy. The current three main approaches to an esophagectomy are the Ivor Lewis technique, McKeown technique, and the transhiatal approach to esophagectomy. Read More
J Addict Med 2018 Dec 12. Epub 2018 Dec 12.
Institute for Clinical and Evaluative Sciences, Toronto, Ontario, Canada (JKE, ASW, PK); Centre for Addiction and Mental Health, Toronto, Ontario, Canada (PK); Northern Ontario School of Medicine, Sudbury, Ontario, Canada (JKE, AMF, DCM).
Objectives: Benzodiazepine (BZD) use is common in patients who are engaged in methadone as a treatment for opioid use disorder. BZD prescribing is generally discouraged for this patient population due to the increased risk of BZD dependence and BZD use disorder, medication-assisted treatment (MAT) discontinuation, and opioid-overdose death. However, some patients have concurrent mental health disorders, where BZD use may be clinically indicated. Read More
J Phys Condens Matter 2018 Dec 13;31(4):045001. Epub 2018 Dec 13.
Department of Physics and Astronomy, Stonehill College, 320 Washington Street, Easton, MA 02357, United States of America. Department of Electrical and Computer Engineering & Photonics Center, Boston University, 8 Saint Mary's St., Boston, MA 02215, United States of America.
Working in the context of the Su-Schreiffer-Heeger model, the effect of topological boundaries on the structure and properties of bulk position-space wavefunctions is studied for a particle undergoing a quantum walk in a one-dimensional lattice. In particular, we consider what happens when the wavefunction reaches a boundary at which the Hamiltonian changes suddenly from one topological phase to another and construct an exact solution for the wavefunction on both sides of the boundary. The reflection and transmission coefficients at the boundary are calculated as a function of the system's hopping parameters, and it is shown that for some parameter ranges the transmission coefficient can be made very small. Read More
Inorg Chem 2018 Dec 13. Epub 2018 Dec 13.
State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province , Lanzhou University , Lanzhou 730000 , People's Republic of China.
A series of mononuclear salen-sodium anions, as the first examples, were synthesized with tetra-alkyl ammonium as a counterpart cation. These complexes are efficient catalysts for the isoselective ring-opening polymerization of rac-lactide; the molecular weights of polymers are under control and molecular weight distributions are narrow when five equivalents of BnOH is used as an initiator. The best isoselectivity value of P = 0. Read More
Chem Commun (Camb) 2018 Dec 13. Epub 2018 Dec 13.
Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781039, India.
C7-Decorated indoles are important structural motifs present in a plethora of bioactive and pharmaceutical compounds. Early stage developments for C7 modifications were realized through directed metallation (DOM) and subsequent quenching with suitable electrophiles or by halogenation with Cu(ii) halides. Direct C-7 functionalization of indoles is comparatively difficult compared to functionalization at C-2 and C-3 positions owing to the inherent reactivity of the pyrrole-type ring. Read More
Turk J Med Sci 2018 12 12;48(6):1372-1374. Epub 2018 Dec 12.
Department of Obstetrics and Gynecology, University of Health Sciences, Etlik Zübeyde Hanım Women’s Health Training and Research Hospital, Ankara, Turkey
Turk J Med Sci 2018 12 12;48(6):1351-1357. Epub 2018 Dec 12.
Department of Medical Microbiology, School of Medicine, Acıbadem University, İstanbul, Turkey
Background/aim: Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry is an alternative way of identifying mycobacteria via the analysis of biomolecules. It is being increasingly used in routine microbiology practice since it permits early, rapid, and cost-effective identification of pathogens of clinical importance. In this study, we aimed to evaluate the efficacy of phenotypic identification of mycobacteria by the MALDI-TOF MS MBT Mycobacteria Library (ML) 4. Read More