237,455 results match your criteria Assessing Writing[Journal]


Assessment of Intermittent Self-Catheterization Procedures in Patients with Neurogenic Lower Urinary Tract Dysfunction: Dutch Translation and Validation of the Intermittent Catheterization Satisfaction Questionnaire, Intermittent Catheterization Acceptance Test, Intermittent Self Catheterization Questionnaire and Intermittent Catheterization Difficulty Questionnaire.

Urol Int 2019 Apr 18:1-6. Epub 2019 Apr 18.

Department of Urology, Ghent University Hospital, Ghent, Belgium.

Background: Intermittent self-catheterization (ISC) is by far the most appealing therapy to achieve a complete bladder emptying in patients with neurogenic lower urinary tract dysfunction (NLUTD). Four questionnaires have been developed in French in order to assess patient's satisfaction, difficulties and acceptance of this technique.

Objectives: The aim of this study was to translate, culturally adapt and validate Dutch versions of the Intermittent Catheterization Satisfaction Questionnaire (InCaSaQ), the Intermittent Catheterization Acceptance Test (ICAT), the Intermittent Self Catheterization Questionnaire (ISCQ) and the Intermittent Catheterization Difficulty Questionnaire (ICDQ). Read More

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http://dx.doi.org/10.1159/000499884DOI Listing

Non-invasive imaging methodologies for assessment of radiation damage to bone marrow and kidneys from peptide receptor radionuclide therapy.

Neuroendocrinology 2019 Apr 19. Epub 2019 Apr 19.


Background/Aims: Peptide receptor radionuclide therapy (PRRT) is becoming clinical routine for management of Neuroendocrine Tumours. The number of PRRT cycles are correlated with treatment effect but theoretically limited by off-target radiation damage to kidneys and bone marrow. New imaging biomarkers for assessment of PRRT tissue damage would enable evaluation of novel renal and bone marrow protective agents, as well as personalized PRRT treatment regiments. Read More

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http://dx.doi.org/10.1159/000500473DOI Listing

Influence of Gamma-Hydroxybutyric Acid-Use and Gamma-Hydroxybutyric Acid-Induced Coma on Affect and the Affective Network.

Eur Addict Res 2019 Apr 18:1-9. Epub 2019 Apr 18.

Department of Psychiatry, Amsterdam Neuroscience, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

Background: Gamma-hydroxybutyric acid (GHB) is a drug of abuse associated with increased emergency room attendances, due to GHB-induced comas. Withdrawal from GHB often increases social anxiety and is linked to alterations in emotion processing. However, little is known about the effects of GHB-use and GHB-induced comas on affect regulation in humans. Read More

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http://dx.doi.org/10.1159/000497381DOI Listing

The Impact of Using Emotionally Arousing Stimuli on Muscle Response Testing Accuracy.

Complement Med Res 2019 Apr 18:1-9. Epub 2019 Apr 18.

School of Health Sciences, City University London, London, United Kingdom.

Introduction: Muscle response testing (MRT) is an assessment method used by 1 million practitioners worldwide, yet its usefulness remains uncertain. The aim of this study, one in a series assessing the accuracy of MRT, was to determine whether emotionally arousing stimuli influence its accuracy compared to neutral stimuli.

Methods: To assess diagnostic test accuracy 20 MRT practitioners were paired with 20 test patients (TPs). Read More

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https://www.karger.com/Article/FullText/497188
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http://dx.doi.org/10.1159/000497188DOI Listing
April 2019
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Trophic transfer of cyclic methyl siloxanes in the marine food web in the Bohai Sea, China.

Ecotoxicol Environ Saf 2019 Apr 15;178:86-93. Epub 2019 Apr 15.

International Joint Research Centre for Persistent Toxic Substances (IJRC-PTS), College of Environmental Science and Engineering, Dalian Maritime University, Dalian, 116026, China. Electronic address:

Trophic transfer of cyclic methyl siloxanes (CMS) in aquatic ecosystems is an important criterion for assessing its environmental risks. This study researched the trophic transfer of four CMS (octamethylcyclotetrasiloxane (D), decamethylcyclopentasiloxane (D), dodecamethylcyclohexasiloxane (D), and tetradecamethylcycloheptasiloxane (D)) in marine food web from zooplankton up to seabirds in the Chinese Bohai Sea. In the zooplankton-invertebrate-fish-seabird based food web, the significant trophic magnifications were found for D to D (D: R = 0. Read More

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http://dx.doi.org/10.1016/j.ecoenv.2019.04.034DOI Listing

Combined effects of environmental xeno-estrogens within multi-component mixtures: Comparison of in vitro human- and zebrafish-based estrogenicity bioassays.

Chemosphere 2019 Apr 9;227:334-344. Epub 2019 Apr 9.

Institut National de l'Environnement Industriel et des risques (INERIS), Unité Ecotoxicologie in vitro et in vivo, UMR-I 02 SEBIO, 60550, Verneuil-en-Halatte, France. Electronic address:

Some recent studies showed that in vitro bioassays based on fish or human estrogen receptor (ER) activation may have distinct responses to environmental samples, highlighting the need to better understand bioassay-specific ER response to environmental mixtures. For this purpose, we investigated a 12-compound mixture in two mixture ratios (M1 and M2) on zebrafish (zf) liver cells stably expressing zfERα (ZELHα cells) or zfERβ2 (ZELHβ2 cells) and on human ER-reporter gene (MELN) cells. The mixture included the well-known ER ligands bisphenol A (BPA) and genistein (GEN), and other compounds representatives of a freshwater background contamination. Read More

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http://dx.doi.org/10.1016/j.chemosphere.2019.04.060DOI Listing

Child sexual abuse, disclosure and PTSD: A systematic and critical review.

Child Abuse Negl 2019 Apr 15;92:196-208. Epub 2019 Apr 15.

Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada.

Background: Child sexual abuse (CSA) is a prevalent exposure with potentially serious, negative health consequences, including post-traumatic stress disorder (PTSD) and its symptomatology.

Objective: To conduct a systematic and critical review in order to investigate the relationship between CSA disclosure patterns and PTSD.

Participants And Setting: Studies included clinical, college and community-based samples of adults' and children's experiences of CSA. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01452134193013
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http://dx.doi.org/10.1016/j.chiabu.2019.04.006DOI Listing
April 2019
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Methylation Tolerance-based Functional Assay to Assess Variants of Unknown Significance in the MLH1 and MSH2 Genes and Identify Patients With Lynch Syndrome.

Gastroenterology 2019 Apr 15. Epub 2019 Apr 15.

Sorbonne Université, Inserm, Centre de Recherche Saint-Antoine, CRSA, F-75012 Paris, France; SIRIC CURAMUS, Equipe labellisée par la Ligue Nationale contre le Cancer. Electronic address:

Background & Aims: Approximately 75% of patients with suspected Lynch syndrome carry variants in MLH1 or MSH2-proteins encoded by these genes are required for DNA mismatch repair (MMR). However, 30% of these are variants of unknown significance (VUS). A assay that measures cell response to the cytotoxic effects of a methylating agent can determine the effects of VUS in MMR genes and identify patients with constitutional mismatch repair-deficiency syndrome. Read More

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http://dx.doi.org/10.1053/j.gastro.2019.03.071DOI Listing

A prospective evaluation of the 'C.O.A.C.H.E.D.' cognitive aid for emergency defibrillation.

Australas Emerg Care 2018 Aug 10;21(3):81-86. Epub 2018 Sep 10.

Sydney Medical School, University of Sydney, Sydney, Australia; Simulated Learning Environment for Clinical Training (SiLECT), Sydney, Australia.

Introduction: International guidelines recommend that interruptions to chest compressions are minimised during defibrillation. As a result, some resuscitation educators have adopted a more structured approach to defibrillation. One such approach is the 'C. Read More

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http://dx.doi.org/10.1016/j.auec.2018.08.002DOI Listing
August 2018
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Does an assessment aid improve Glasgow Coma Scale scoring by helicopter rescuers in Hong Kong: A randomised controlled trial.

Australas Emerg Care 2018 Aug 25;21(3):105-110. Epub 2018 Jun 25.

Accident and Emergency Medicine Academic Unit, Chinese University of Hong Kong, Hong Kong Special Administrative Region.

Background: Glasgow Coma Scale (GCS) is one of the most commonly used patient assessment tools. This study aimed to determine whether an assessment aid can improve the GCS scoring accuracy by helicopter rescuers in Hong Kong.

Methods: In this randomised controlled trial, Air Crewman Officers (ACMOs) of Government Flying Service in Hong Kong were randomised into two groups, with and without assessment aid. Read More

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http://dx.doi.org/10.1016/j.auec.2018.06.001DOI Listing

Utility of Ophthalmologic Screening for Patients With Candida Bloodstream Infections: A Systematic Review.

JAMA Ophthalmol 2019 Apr 18. Epub 2019 Apr 18.

Vanderbilt University School of Medicine, Nashville, Tennessee.

Importance: The Infectious Diseases Society of America recommends ophthalmologic examinations for everyone with positive Candida blood culture results (candidemia) to screen for endophthalmitis, a practice that remains controversial because of multiple concerns for its limited usefulness and potential for harm.

Objective: To determine guideline efficacy by reconciling discrepancies in the incidence of endophthalmitis and evaluating outcomes of studies assessing ophthalmologic screening for candidemia.

Evidence Review: PubMed literature searches, including the search terms candidemia, fungemia, chorioretinitis, and endophthalmitis, identified longitudinal studies prior to 2018 of patients who underwent ophthalmologic evaluations in the setting of positive fungal blood culture results regardless of symptoms or clinical status. Read More

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http://dx.doi.org/10.1001/jamaophthalmol.2019.0733DOI Listing

Comparison of the 18-item and 6-item Lubben Social Network Scales with community-dwelling older adults in Mongolia.

PLoS One 2019 18;14(4):e0215523. Epub 2019 Apr 18.

Wayne State University, Detroit, Michigan, United States of America.

This study compares the psychometric properties of two versions of the Lubben Social Network Scale (LSNS-18 and LSNS-6) with community dwelling older adults in Mongolia. We recruited 650 older adult in the capital city of Ulaanbaatar and the country's four rural regions. We used the Geriatric Depression Scale (GDS-15), the Short Form 12 (SF-12) physical and mental health functioning measures, and a multi-dimensional scale of social isolation for confirmatory factor analyses of the LSNS-18 and the LSNS-6. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215523PLOS

Pepper mild mottle virus: Agricultural menace turned effective tool for microbial water quality monitoring and assessing (waste)water treatment technologies.

PLoS Pathog 2019 Apr 18;15(4):e1007639. Epub 2019 Apr 18.

College of Marine Science, University of South Florida, Saint Petersburg, Florida, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1007639DOI Listing

Population prevalence of myopia, glasses wear and free glasses acceptance among minority versus Han schoolchildren in China.

PLoS One 2019 18;14(4):e0215660. Epub 2019 Apr 18.

Lancang County First People's Hospital, Lancang, Yunnan, China.

Aim: To measure myopia, glasses wear and free glasses acceptance among minority and Han children in China.

Methods: Visual acuity testing and questionnaires assessing ethnicity, study time, and parental and teacher factors were administered to a population-based sample of 9-12 year old minority and Han children in Yunnan and Guangdong, and their teachers and parents. Refraction was performed on children with uncorrected visual acuity (VA) < = 6/12 in either eye, and acceptance of free glasses assessed. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215660PLOS

Phase space methods for non-linear analysis of pedalling forces in cycling.

PLoS One 2019 18;14(4):e0198914. Epub 2019 Apr 18.

Department of Human Movement Science and Health, Chemnitz University of Technology, Chemnitz, Germany.

Introduction: From the perspective of dynamic systems theory, stability and variability of biological signals are both understood as a functional adaptation to variable environmental conditions. In the present study, we examined whether this theoretical perspective is applicable to the pedalling movement in cycling. Non-linear measures were applied to analyse pedalling forces with varying levels of subjective load. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0198914PLOS

Is the timing of menarche correlated with mortality and fertility rates?

PLoS One 2019 18;14(4):e0215462. Epub 2019 Apr 18.

Department of Anthropology, University of Utah, Salt Lake City, Utah, United States of America.

Timing of menarche has largely been studied in the context of a secular trend. However, since mortality and fertility rates are fundamental demographic factors linked to a population's developmental and reproductive characteristics, we expect that the timing of menarche, a precondition to reproduction, is also associated with these vital rates. We conduct an analysis of 89 countries and 21 demographic, socioeconomic, nutritional, and educational variables selected for their known influence on menarche. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215462PLOS

Test-retest reliability of BSP, a battery of tests for assessing spatial cognition in visually impaired children.

PLoS One 2019 18;14(4):e0212006. Epub 2019 Apr 18.

Unit for Visually Impaired People, Center for Human Technologies, Fondazione Istituto Italiano di Tecnologia, Genoa, Italy.

Blind individuals are particularly dependent on their hearing for defining space. It has been found that both children and adults with visual impairments can struggle with complex spatial tasks that require a metric representation of space. Nonetheless the variability of methods employed to assess spatial abilities in absence of vision is wide, especially in the case of visually impaired children. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212006PLOS

Where Do We Look? Assessing Gaze Patterns in Cosmetic Facelift Surgery with Eye Tracking Technology.

Plast Reconstr Surg 2019 Apr 9. Epub 2019 Apr 9.

Division of Plastic and Reconstructive Surgery, Stanford University, Palo Alto Stanford School of Medicine, Palo Alto Stanford School of Medicine, Palo Alto Division of Plastic and Reconstructive Surgery, Stanford University, Palo Alto Division of Plastic and Reconstructive Surgery, Stanford University, Palo Alto Division of Plastic and Reconstructive Surgery, Stanford University, Palo Alto.

Purpose: Aesthetics plays a central role in determining success in plastic surgery. Understanding perceptions of favorable aesthetics is critical to ensure patient satisfaction. Eye-tracking technology offers an objective way to evaluate attention and understand how viewers direct their focus in patients who undergo cosmetic facelift procedures. Read More

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http://dx.doi.org/10.1097/PRS.0000000000005700DOI Listing

Trochanteric Fractures in Young Children.

Pediatr Emerg Care 2019 Apr 16. Epub 2019 Apr 16.

From the Department of Trauma and Orthopaediatrics, University Hospital of Wales, Cardiff, United Kingdom.

Background: Isolated avulsion fractures of the greater and lesser trochanter are usually seen in adolescents prior to the fusion of the apophysis. Greater trochanter fractures in adults have a high incidence of intertrochanteric extension and lesser trochanter fractures are regarded as a pathognomonic sign of metastatic disease. These fractures are very rare among children. Read More

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http://dx.doi.org/10.1097/PEC.0000000000001825DOI Listing
April 2019
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Does Compensatory Anterior Pelvic Tilt Decrease After Bilateral Periacetabular Osteotomy?

Clin Orthop Relat Res 2019 May;477(5):1168-1175

E. Daley, I. Zaltz, Department of Orthopedic Surgery, Beaumont Health, Royal Oak, MI, USA N. Nahm, Department of Orthopedic Surgery, Henry Ford Hospital, Detroit, MI, USA D. Koueiter, Orthopedic Research Laboratories, Beaumont Health, Royal Oak, MI, USA.

Background: The kinetic link among the lumbar spine, pelvic tilt, and the hip has been hypothesized, but this relationship requires further study in acetabular dysplasia. Anecdotal reports suggest that patients may compensate for acetabular dysplasia with an involuntary increase in anterior pelvic tilt; it is not known if this relationship is affected by acetabular reorientation.

Questions/purposes: (1) Does compensatory pelvic tilt decrease on preoperatively obtained standing AP pelvis radiographs compared with those obtained at a minimum of 6 months after bilateral periacetabular osteotomy (PAO)? (2) Does a modified surrogate measurement of pelvic tilt, the pubic symphysis to sacroiliac (PS-SI) index, correlate with a physical synthetic bones model in which pelvic tilt can be directly measured? (3) Can the PS-SI index demonstrate high interrater reliability?

Methods: We assessed the surgical records of one surgeon, who participates in the longitudinally maintained Academic Network of Conservational Hip Outcomes Research (ANCHOR) registry, for patients who had undergone the second side of a staged bilateral PAO between 2007 and 2016; there were 113 such patients. Read More

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http://dx.doi.org/10.1097/CORR.0000000000000560DOI Listing

The Fear of Tinnitus Questionnaire: Toward a Reliable and Valid Means of Assessing Fear in Adults with Tinnitus.

Ear Hear 2019 Apr 10. Epub 2019 Apr 10.

Department of Clinical Psychological Science, Maastricht University, Maastricht, The Netherlands.

Objectives: The purpose of this study was to assess the factor structure, reliability, and validity of the Fear of Tinnitus Questionnaire (FTQ); a brief self-report measure of people's fears about potential cognitive, emotional, behavioral, and social consequences of living with tinnitus.

Design: Five hundred eighty-eight Dutch-speaking adults with tinnitus completed an online battery of questionnaires measuring tinnitus-related distress, fear, catastrophizing, and quality of life. The sample was randomly split into two to perform exploratory and Bayesian confirmatory factor analyses. Read More

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http://dx.doi.org/10.1097/AUD.0000000000000728DOI Listing

A re-evaluation of chironomid deformities as an environmental stress response: avoiding survivorship bias and testing noncontaminant biological factors.

Environ Toxicol Chem 2019 Apr 18. Epub 2019 Apr 18.

School of BioSciences, University of Melbourne, VIC, Australia.

Larval deformities have been observed in chironomids, and are thought to be associated with aquatic contaminant exposure. However, deformities have not been linked with contaminants in the absence of potential confounding variables including mortality in laboratory assays, which introduces a survivorship bias (SB). There is also a paucity of data on noncontaminant causes. Read More

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http://dx.doi.org/10.1002/etc.4446DOI Listing

Assessing alignment between functional markers and ordinal outcomes based on broad sense agreement.

Biometrics 2019 Apr 18. Epub 2019 Apr 18.

Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia.

Functional markers and their quantitative features (eg, maximum value, time to maximum, area under the curve [AUC], etc) are increasingly being used in clinical studies to diagnose diseases. It is thus of interest to assess the diagnostic utility of functional markers by assessing alignment between their quantitative features and an ordinal gold standard test that reflects the severity of disease. The concept of broad sense agreement (BSA) has recently been introduced for studying the relationship between continuous and ordinal measurements, and provides a promising tool to address such a question. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/biom.13063
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http://dx.doi.org/10.1111/biom.13063DOI Listing
April 2019
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[Efficacy and Safety of Decitabine Combined with CAG (Cytarabine, Aclarubicin, G-CSF) for Patients with Intermediate or High Risk Myelodysplastic Syndrome and Acute Myeloid Leukemia: a Meta-Analysis].

Zhongguo Shi Yan Xue Ye Xue Za Zhi 2019 Apr;27(2):494-503

Fujian Institute of Hematology,Fujian Provincial Key Laboratory on Hematology,Fujian Medical University Union Hospital, Fuzhou 350001, Fujian Province, China.

Objective: To systematically evaluate the efficacy and safety of DCAG regimen for treating the intermediate or high risk MDS and AML.

Methods: PubMed, EMbase, The Cochrane Library, WanFang Data and CNKI databases were searched to collect randomized controlled trials (RCTs) of decitabine combined with CAG regimen for intermediate or high risk MDS and AML from inception to March, 2018. The quality of each RCT was evaluated by the Cochrane collaboration´s tool for assessing the risk of bias. Read More

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http://dx.doi.org/10.19746/j.cnki.issn.1009-2137.2019.02.030DOI Listing
April 2019
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The System for Coding Interactions and Family Functioning (SCIFF) in low-income and urban adolescents.

Psychol Assess 2019 Apr 18. Epub 2019 Apr 18.

Department of Psychology.

Reliable, brief, and cost-effective methods to assess parenting are critical for advancing etiological research and translational efforts within parenting science. In the current study, we adapted the System for Coding Interactions and Family Functioning (SCIFF) for use among a sample of mostly racial minority adolescents aged 15 years old, growing up in a low-income urban setting. A multiethnic team coded videotapes of a family interaction task designed to elicit conflict. Read More

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http://dx.doi.org/10.1037/pas0000719DOI Listing

Tracing molybdenum attenuation in mining environments using molybdenum stable isotopes.

Environ Sci Technol 2019 Apr 18. Epub 2019 Apr 18.

Molybdenum contamination is a concern in mining regions worldwide. Better understanding of processes controlling Mo mobility in mine wastes is critical for assessing potential impacts and developing water-quality management strategies associated to this element. Here, we used Mo stable isotope (δMo) analyses to investigate geochemical controls on Mo mobility within a tailings management facility (TMF) featuring oxic and anoxic environments. Read More

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http://dx.doi.org/10.1021/acs.est.9b00766DOI Listing

Revisiting the influence of individual factors on heat exchange during exercise in dry heat using direct calorimetry.

Exp Physiol 2019 Apr 18. Epub 2019 Apr 18.

Human and Environmental Physiology Research Unit, School of Human Kinetics, University of Ottawa, Ottawa, Canada.

New Findings: What is the central question of this study? To identify the greatest contributor(s) to the variation in whole-body heat exchange, as assessed using direct calorimetry, among young men and women with heterogeneous characteristics during exercise at increasing metabolic heat production rates in dry-heat. What is the main finding and its importance? The evaporative heat loss requirement, body morphology and aerobic fitness contributed greatest to the individual variation in evaporative and dry heat exchange, with the variance explained being exercise intensity-dependent. These findings provide a foundation to build our ability to explain the individual variation in heat exchange during exercise-heat stress. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1113/EP087666
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http://dx.doi.org/10.1113/EP087666DOI Listing
April 2019
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Assessing the nephrotoxicity of intravenous iodinated contrast agents in patients with chronic renal failure in the absence of interfering acute disease.

Acta Radiol 2019 Apr 18:284185119840764. Epub 2019 Apr 18.

1 Department of Radiology, Parc Taulí Hospital Universitari, Institut d'Investigació i Innovació Parc Taulí I3PT, Sabadell, Spain.

Background: The existence of contrast-induced nephropathy is widely accepted. Recent studies suggest its incidence has been overestimated.

Purpose: To determine the effect of intravenous iodinated contrast agents on renal function in patients with chronic renal failure without acute disease that can interfere with the assessment of renal function. Read More

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http://dx.doi.org/10.1177/0284185119840764DOI Listing

Wash-in/wash-out phase xenon-enhanced area-detector CT (ADCT): utility for regional ventilation, pulmonary functional loss and clinical stage evaluations of smokers.

Acta Radiol 2019 Apr 18:284185119840647. Epub 2019 Apr 18.

1 Division of Functional and Diagnostic Imaging Research, Department of Radiology, Kobe University Graduate School of Medicine, Kobe, Japan.

Background: Xenon (Xe)-enhanced area-detector computed tomography (ADCT) can visualize regional distribution of Xe within the lungs and demonstrate regional ventilation differences in smokers and patients with pulmonary diseases.

Purpose: The purpose of this study was to evaluate the capability of wash-in and wash-out (WI/WO) phase Xe-enhanced ADCT for detecting regional ventilation differences based on underlying lung conditions, pulmonary functional loss evaluation, and clinical stage prediction for smokers with and without chronic obstructive pulmonary disease (COPD).

Material And Methods: The pulmonary function test as well as inspiratory/expiratory unenhanced and WI/WO phase Xe-enhanced ADCT were prospectively administered to a group of 40 smokers consisting of 25 men (mean age ± standard deviation [SD] = 65. Read More

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http://journals.sagepub.com/doi/10.1177/0284185119840647
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http://dx.doi.org/10.1177/0284185119840647DOI Listing
April 2019
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Intraoperative colonoscopy in laparoscopic colorectal surgery: A review of recent publications.

Asian J Endosc Surg 2019 Apr 17. Epub 2019 Apr 17.

Department of Surgery, The University Hong Kong-Shenzhen Hospital, Shenzhen, China.

Introduction: Laparoscopic colorectal resection is becoming the gold standard for treating colorectal cancers because it offers superior short-term and comparable long-time outcomes compared to open surgery. Intraoperative colonoscopy (IOC) is increasingly performed for tumor localization and mucosal assessment. The aim of this report was to review the safety and efficacy of IOC in laparoscopic colorectal surgery. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/ases.12704
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http://dx.doi.org/10.1111/ases.12704DOI Listing
April 2019
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Can Cyanuric Acid and 2,4,6-Triaminopyrimidine Containing Ribonucleosides be Components of Prebiotic RNA? Insights from QM Calculations and MD Simulations.

Chemphyschem 2019 Apr 17. Epub 2019 Apr 17.

University of Lethbridge, Department of Chemistry and Biochemistry, 4401 University Drive West, T1K 3M4, Lethbridge, CANADA.

As a step toward assessing their fitness as pre-RNA nucleobases, we employ DFT and MD simulations to analyze the noncovalent interactions of cyanuric acid (CA) and 2,4,6-triaminopyrimidine (TAP), and the structural properties of the associated ribonucleosides (rNs) and oligonucleotides. Our calculations reveal that the TAP:CA pair has a comparable hydrogen-bond strength to the canonical A:U pair. This strengthens the candidature of CA and TAP as prebiotic nucleobases. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/cphc.2019002
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http://dx.doi.org/10.1002/cphc.201900237DOI Listing
April 2019
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A novel alarm signal in aquatic prey: Familiar minnows coordinate group defences against predators through chemical disturbance cues.

J Anim Ecol 2019 Apr 17. Epub 2019 Apr 17.

Department of Biology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.

Animal signalling systems outside the realm of human perception remain largely understudied. These systems consist of four main components: a signalling context, a voluntary signal, receiver responses and resulting fitness benefits to both the signaller and receiver(s). It is often most difficult to determine incidental cues from voluntary signals. Read More

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http://dx.doi.org/10.1111/1365-2656.12986DOI Listing

Implementing a central composite design for the optimization of solid phase microextraction to establish the urinary volatomic expression: a first approach for breast cancer.

Metabolomics 2019 Apr 17;15(4):64. Epub 2019 Apr 17.

CQM-Centro de Química da Madeira, Universidade da Madeira, Campus Universitário da Penteada, 9020-105, Funchal, Portugal.

Introduction: Breast cancer (BC) is positioned as the second among all cancers remaining at the top of women´s diseases worldwide followed by colorectum, lung, cervix, and thyroid cancers. The main drawback of most the screening/diagnostic methods is their low sensitivity/specificity and in some cases the invasive procedure required to obtain the samples.

Objectives: On the present investigation, we report a statistical design was to evaluate by central composite design the influence towards the optimization of the most significant variables of solid-phase microextraction (SPME) procedure for the isolation of volatile organic metabolites (VOMs) from urine of BC patients (N = 31) and healthy individuals (CTL; N = 40). Read More

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http://link.springer.com/10.1007/s11306-019-1525-2
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http://dx.doi.org/10.1007/s11306-019-1525-2DOI Listing
April 2019
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Adenotonsillectomy in children with syndromic craniosynostosis: a systematic review and meta-analysis.

Eur Arch Otorhinolaryngol 2019 Apr 17. Epub 2019 Apr 17.

Department of Otorhinolaryngology Head and Neck Surgery, Police General Hospital, 492/1 Rama 1 Road, Patumwan, Bangkok, Thailand.

Objective: To conduct a systematic review and meta-analysis in children with syndromic craniosynostosis, to evaluate the effect of adenotonsillectomy for the treatment of obstructive sleep apnea (OSA).

Study Design: A systematic review and meta-analysis.

Search Methods: Data sources: a comprehensive search of PubMed, SCOPUS, Ovid Medline, and Web of science databases was performed through June 22nd, 2018. Read More

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http://dx.doi.org/10.1007/s00405-019-05427-3DOI Listing

Assessing the efficiency in assisted depuration of coffee processing wastewater from mixed wild microbial selected inoculum.

Environ Monit Assess 2019 Apr 17;191(5):284. Epub 2019 Apr 17.

Department of Biology, Universidade Federal de Lavras. Campus Universitário, CEP: 37.200-000, Lavras, MG, Brazil.

This work evaluated the efficiency of bacterial bio-augmentation to the biological treatment of coffee processing wastewater (CPWW) in a pilot wastewater treatment plant (WTP). Biochemical oxygen demand (BOD) and chemical oxygen demand (COD) values were the basis for the treatment efficiency. Serratia marcescens CCMA 1010 and CCMA 1013, Corynebacterium flavescens CCMA 1006 and Acetobacter indonesiensis CCMA 1002 were previously selected. Read More

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http://dx.doi.org/10.1007/s10661-019-7398-zDOI Listing

Improved micronutrient status and health outcomes in low- and middle-income countries following large-scale fortification: evidence from a systematic review and meta-analysis.

Am J Clin Nutr 2019 Apr 17. Epub 2019 Apr 17.

Centre for Global Child Health, Hospital for Sick Children, Toronto, Canada.

Background: Micronutrient malnutrition is highly prevalent in low- and middle-income countries (LMICs) and disproportionately affects women and children. Although the effectiveness of large-scale food fortification (LSFF) of staple foods to prevent micronutrient deficiencies in high-income settings has been demonstrated, its effectiveness in LMICs is less well characterized. This is important as food consumption patterns, potential food vehicles, and therefore potential for impact may vary substantially in these contexts. Read More

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http://dx.doi.org/10.1093/ajcn/nqz023DOI Listing

Assessing oil accumulation in the oleaginous yeast JRC1 using dairy waste cheese whey as a substrate.

3 Biotech 2019 May 10;9(5):173. Epub 2019 Apr 10.

Environmental Biotechnology Laboratory, Department of Bioscience and Bioengineering, Indian Institute of Technology Jodhpur (IIT J), Jodhpur, Rajasthan 342037 India.

This study assesses the potential for the lipid production by the oleaginous yeast JRC1 using dairy industry waste cheese whey as a substrate. Cheese whey was used either untreated (UCW) or deproteinized (DCW) at different concentrations (25-100%) to serve as the carbon and energy source. Both UCW and DCW supported high biomass and lipid productivities. Read More

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http://dx.doi.org/10.1007/s13205-019-1701-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458212PMC

POST-CONCUSSIVE CHANGES IN BALANCE AND POSTURAL STABILITY MEASURED WITH CANESENSE™ AND THE BALANCE ERROR SCORING SYSTEM (BESS) IN DIVISION I COLLEGIATE FOOTBALL PLAYERS: A CASE SERIES.

Int J Sports Phys Ther 2019 Apr;14(2):296-307

UHealth Sports Medicine Institute, University of Miami Miller School of Medicine, Miami, FL.

Introduction: Impairments in postural stability have been identified following sports-related concussion. CaneSense™ is a recently developed mobile lower limb motion capture system and mobile application for movement assessment which provides an objective measure of postural stability. One of the components within CaneSense™ is the Post-Concussive Excursion Index (PCEI), a measure of postural stability expressed as a percentage of symmetry between lower limbs. Read More

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THE MODIFIED STAR EXCURSION BALANCE AND Y-BALANCE TEST RESULTS DIFFER WHEN ASSESSING PHYSICALLY ACTIVE HEALTHY ADOLESCENT FEMALES.

Int J Sports Phys Ther 2019 Apr;14(2):192-203

Background: The modified Star Excursion Balance Test (mSEBT) and Y-Balance Test (YBT) are two common methods for clinical assessment of dynamic balance. Clinicians often use only one of these test methods and one outcome factor when screening for lower extremity injury risk. Dynamic balance scores are known to vary by age, sex and sport. Read More

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Neural networks for automatic scoring of arthritis disease activity on ultrasound images.

RMD Open 2019 30;5(1):e000891. Epub 2019 Mar 30.

Department of Rheumatology, Odense Universitetshospital, Odense, Denmark.

Background: The development of standardised methods for ultrasound (US) scanning and evaluation of synovitis activity by the OMERACT-EULAR Synovitis Scoring (OESS) system is a major step forward in the use of US in the diagnosis and monitoring of patients with inflammatory arthritis. The variation in interpretation of disease activity on US images can affect diagnosis, treatment and outcomes in clinical trials. We, therefore, set out to investigate if we could utilise neural network architecture for the interpretation of disease activity on Doppler US images, using the OESS scoring system. Read More

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http://rmdopen.bmj.com/lookup/doi/10.1136/rmdopen-2018-00089
Publisher Site
http://dx.doi.org/10.1136/rmdopen-2018-000891DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443126PMC
March 2019
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Re-treatment with abatacept plus methotrexate for disease flare after complete treatment withdrawal in patients with early rheumatoid arthritis: 2-year results from the AVERT study.

RMD Open 2019 8;5(1):e000840. Epub 2019 Feb 8.

Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands.

Objectives: To complete reporting of outcomes after total withdrawal of all rheumatoid arthritis (RA) therapy and re-treatment after flare in Assessing Very Early Rheumatoid arthritis Treatment study (NCT01142726).

Methods: Patients with early RA were initially randomised to double-blind, weekly subcutaneous abatacept plus methotrexate, or abatacept or methotrexate monotherapy. At month 12, patients with Disease Activity Score (DAS)28 C reactive protein (CRP) <3. Read More

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http://dx.doi.org/10.1136/rmdopen-2018-000840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446179PMC
February 2019

OMERACT agreement and reliability study of ultrasonographic elementary lesions in osteoarthritis of the foot.

RMD Open 2019 8;5(1):e000795. Epub 2019 Mar 8.

Scienze Cliniche e Biologiche, Università degli Studi di Torino, Rome, Italy.

Objective: To evaluate the level of agreement on ultrasonographic (US) lesions among highly experienced sonographers as well as the intraobserver and interobserver reliability of inflammatory and structural US lesions in patients with osteoarthritis (OA) of the foot.

Methods: After a systematic literature review, a Delphi survey was performed to test definitions of US lesions in OA of the foot, including inflammatory lesions (ie, synovial hypertrophy [SH], joint effusion [JE], power Doppler signal [PD]), and structural abnormalities (ie, cartilage damage [CD] and osteophytes). Subsequently, the reliability of US in assessing the aforementioned lesions was tested on static images as well as during a live exercise. Read More

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http://dx.doi.org/10.1136/rmdopen-2018-000795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443136PMC

A novel behavioural INTErvention to REduce Sitting Time in older adults undergoing orthopaedic surgery (INTEREST): protocol for a randomised controlled feasibility study.

Pilot Feasibility Stud 2019 6;5:54. Epub 2019 Apr 6.

1School of Sport, Exercise, and Rehabilitation Sciences, University of Birmingham, Birmingham, B15 2TT UK.

Background: Osteoarthritis is a highly prevalent condition in older adults, that causes many sufferers to require a hip or knee replacement in order to improve their quality of life and reduce pain. Individuals waiting for hip or knee replacements are often highly sedentary; thus, it is pertinent to assess whether reducing their sedentariness prior to surgery may aid in improving post-operative outcomes.

Methods/design: The study will be a randomised controlled feasibility trial design, with 2:1 randomisation into an intervention and usual care group respectively. Read More

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http://dx.doi.org/10.1186/s40814-019-0437-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451782PMC

Genotoxicity of zinc oxide nanoparticles: an and study.

Toxicol Res (Camb) 2019 Mar 30;8(2):277-286. Epub 2019 Jan 30.

Laboratory of Genetic Toxicity , Graduate Program in Molecular and Cellular Biology Applied to Health , Lutheran University of Brazil (ULBRA) , Canoas , RS , Brazil . Email: ; ; Tel: + 55 51 34779219.

Zinc oxide (ZnO) NPs are being used worldwide in consumer products and industrial applications. Based on predefined pathways, this study synthesized and characterized the nanostructures of ZnO NPs. The genotoxic effects of these nanomaterials were evaluated using a short-term bioassay, the somatic mutation and recombination test (SMART) in . Read More

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http://xlink.rsc.org/?DOI=C8TX00255J
Publisher Site
http://dx.doi.org/10.1039/c8tx00255jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430083PMC
March 2019
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Model peptide for anti-sigma factor domain HHCC zinc fingers: high reactivity toward O leads to domain unfolding.

Chem Sci 2019 Mar 21;10(12):3608-3615. Epub 2019 Feb 21.

Univ. Grenoble Alpes , CNRS , CEA , BIG , LCBM (UMR 5249) , F-38000 Grenoble , France . Email:

All organisms have to cope with the deleterious effects of reactive oxygen species. Some of them are able to mount a transcriptional response to various oxidative stresses, which involves sensor proteins capable of assessing the redox status of the cell or to detect reactive oxygen species. In this article, we describe the design, synthesis and characterization of Zn·L(HHCC), a model for the Zn(Cys)(His) zinc finger site of ChrR, a sensor protein involved in the bacterial defence against singlet oxygen that belongs to the family of zinc-binding anti-sigma factors possessing a characteristic H/C-X-H-X-C-X-C motif. Read More

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http://dx.doi.org/10.1039/c9sc00341jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432622PMC

Assessing the stability and techno-economic implications for wet storage of harvested microalgae to manage seasonal variability.

Biotechnol Biofuels 2019 8;12:80. Epub 2019 Apr 8.

3Arizona State University, Mesa, AZ 85212 USA.

Background: Seasonal variation in microalgae production is a significant challenge to developing cost-competitive algae biofuels. Summer production can be three to five times greater than winter production, which could result in winter biomass shortages and summer surpluses at algae biorefineries. While the high water content (80%, wet basis) of harvested microalgae biomass makes drying an expensive approach to preservation, it is not an issue for ensiling. Read More

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http://dx.doi.org/10.1186/s13068-019-1420-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452513PMC

Cobb Angle Measurement of Spine from X-Ray Images Using Convolutional Neural Network.

Comput Math Methods Med 2019 19;2019:6357171. Epub 2019 Feb 19.

Department of Computer Science and Information Engineering, National Cheng Kung University, Tainan, Taiwan.

Scoliosis is a common spinal condition where the spine curves to the side and thus deforms the spine. Curvature estimation provides a powerful index to evaluate the deformation severity of scoliosis. In current clinical diagnosis, the standard curvature estimation method for assessing the curvature quantitatively is done by measuring the Cobb angle, which is the angle between two lines, drawn perpendicular to the upper endplate of the uppermost vertebra involved and the lower endplate of the lowest vertebra involved. Read More

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http://dx.doi.org/10.1155/2019/6357171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399566PMC
February 2019

Identification of neonatal abstinence syndrome in the community: Infants born into Canada's opioid crisis.

Authors:
Amanda Haas

Paediatr Child Health 2019 May 14;24(2):81-84. Epub 2018 Aug 14.

University of Saskatchewan - College of Nursing, Saskatoon, Saskatchewan, Saskatchewan.

Opioid use in Canada continues to rise. Infants exposed to opioids in utero are at high risk for neonatal abstinence syndrome. Signs and symptoms of withdrawal may not develop before the infant is discharged home. Read More

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http://dx.doi.org/10.1093/pch/pxy098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462139PMC

[Spinal cord stimulation for non-reconstructable chronic ritical limb ischemiae: a case report].

Beijing Da Xue Xue Bao Yi Xue Ban 2019 Apr;51(2):362-364

Department of Vascular Surgery, Peking University People's Hospital, Beijing 100044, China.

Peripheral arterial disease is one part of systematic atherosclerosis, becoming a heavy burden of human health. Patients in end stage of peripheral arterial disease manifest critical limb ischemia with severe rest pain and refractory ulcer. Surgical revascularization is the optimal option for patients with critical limb ischemia to avoid major amputation and improve quality of life. Read More

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