969 results match your criteria Asplenia Polysplenia
J Surg Res 2018 Dec 14;232:293-297. Epub 2018 Jul 14.
Trauma/Critical Care Division, University of Kansas Medical Center, Kansas City, Kansas. Electronic address:
Background: The spleen is the second most commonly injured solid organ during blunt abdominal trauma. Although total splenectomy is frequently performed for injury, splenic rupture can also be managed by splenic embolization. For these patients, current Advisory Committee on Immunization Practices (ACIP) recommendations indicate that if 50% or more of the splenic mass is lost, patients should be treated as though they are asplenic. Read More
Digestion 2018 Nov 13:1-6. Epub 2018 Nov 13.
Interdisziplinäre Ultraschallzentrum, Universitätsklinikum Gießen und Marburg, Philipps Universität Marburg, Marburg, Germany.
Purpose: In contrast to splenomegaly, the clinical value of a small spleen (hyposplenia) is unclear. Contrast-enhanced ultrasound (CEUS) has not been investigated systematically in hyposplenia.
Methods: Between February 2005 and January 2017, 43 patients with hyposplenia (< 7 × 3 cm) were examined by B-mode ultrasound (US) and CEUS. Read More
Cureus 2018 Aug 29;10(8):e3227. Epub 2018 Aug 29.
Internal Medicine, Case Western Reserve University School of Medicine, Cleveland, USA.
empyema is a rare complication of pneumonia. We report the case of a 67-year-old asplenic man with pneumonia complicated by respiratory failure and empyema requiring decortication and prolonged chest tube drainage. Cultures of the empyema were initially negative, but later grew vancomycin-resistant (VRE), which was successfully treated with linezolid. Read More
HeartRhythm Case Rep 2018 Oct 17;4(10):480-483. Epub 2018 Jul 17.
Department of Cardiology, Saitama Medical University International Medical Center, Saitama, Japan.
J Pediatric Infect Dis Soc 2018 Oct 25. Epub 2018 Oct 25.
Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia.
Background: Existing data on the clinical features and outcomes of immunocompromised children with influenza are limited.
Methods: Data from the 2011-2012 through 2014-2015 influenza seasons were collected as part of the Centers for Disease Control and Prevention (CDC) Influenza Hospitalization Surveillance Network (FluSurv-NET). We compared clinical features and outcomes between immunocompromised and nonimmunocompromised children (<18 years old) hospitalized with laboratory-confirmed community-acquired influenza. Read More
J Assoc Physicians India 2018 Jan;66(1):102-103
Medical Officer of Medicine, PGIMER and Dr. RML Hospital, New Delhi.
Adult onset Still's disease (AOSD) is a rare inflammatory disorder of unknown etiology. It is a diagnosis of exclusion. We report a case of post-splenectomised man, presented with high grade fever, joint pain and body ache. Read More
Development 2018 Oct 18;145(20). Epub 2018 Oct 18.
Pediatric Genomics Discovery Program, Departments of Pediatrics and Genetics, Yale University School of Medicine, 333 Cedar Street, New Haven, Connecticut 06510, USA
A growing number of tissue-specific inherited disorders are associated with impaired ribosome production, despite the universal requirement for ribosome function. Recently, mutations in RPSA, a protein component of the small ribosomal subunit, were discovered to underlie approximately half of all isolated congenital asplenia cases. However, the mechanisms by which mutations in this ribosome biogenesis factor lead specifically to spleen agenesis remain unknown, in part due to the lack of a suitable animal model for study. Read More
Aust N Z J Public Health 2018 Oct 20;42(5):463-466. Epub 2018 Sep 20.
Deakin Health Economics, Deakin University, Victoria.
Objective: To validate our estimates from our original model and re-evaluate the cost-effectiveness of Spleen Australia, the Australian post-splenectomy registry, using our original model with updated model parameters based on advances in the literature and experience of the registry over the past decade.
Methods: We revisited a decision model from 2005, comparing 1,000 hypothetical registered patients with asplenia or hyposplenism against 1,000 who were not registered, and updated the model parameters. The cost-effectiveness of the registry was evaluated from a healthcare perspective in terms of additional cost per case of overwhelming post-splenectomy infection (OPSI) avoided and as additional cost per life year gained. Read More
Patient Prefer Adherence 2018 28;12:1607-1617. Epub 2018 Aug 28.
Department of Surgery, University Medical Centre Utrecht, Utrecht, the Netherlands,
Purpose: Asplenic patients are at increased risk for the development of overwhelming postsplenectomy infection (OPSI) syndrome. It is believed that adequate immunization, antimicrobial prophylaxis, as well as appropriate education concerning risks on severe infection lead to the decreased incidence of OPSI. The aim of this study was to analyze the methods used to prevent OPSI in trauma patients splenectomized before the age of 18. Read More
Hum Vaccin Immunother 2018 Sep 7:1-7. Epub 2018 Sep 7.
a Faculty of Medicine, Department of Pediatrics , Eskisehir Osmangazi University , Eskisehir , Turkey.
Introduction: Bacterial meningitis is one of the leading causes of morbidity and mortality among children and adults. Better understanding of the seroepidemiology of meningitis is critical for both the selection and implementation of an effective meningitis vaccine for the national immunization program. Because physicians play a crucial role in the implementation of this vaccine, the aim of this study was to evaluate the attitudes, behaviors, and knowledge of healthcare professionals in Turkey regarding the diagnosis, treatment and prevention of bacterial meningitis, especially pneumococcal and meningococcal meningitis. Read More
Farm Hosp 2018 09 1;42(5):191-196. Epub 2018 Sep 1.
Department of Epidemiological Surveillance. Directorate General of Public Health, Regional Ministry of Health of the Principality of Asturias, Oviedo..
Objective: To know the safety profile of the 4CMenB vaccine in adults in special situations.
Method: Security prospective study of phase IV. Inclusion criteria and some vaccination conditions were applied. Read More
Clin Chest Med 2018 Sep;39(3):515-524
Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA 15213, USA. Electronic address:
Venous thromboembolism (VTE) is a common cause of morbidity and mortality. Presence of preexisting conditions, such as cardiopulmonary diseases, cirrhosis, renal dysfunction, and asplenia, commonly occurs in VTE patients. Moreover, these conditions often are risk factors for developing VTE. Read More
Front Immunol 2018 30;9:1738. Epub 2018 Jul 30.
Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
B-1a cells are mainly generated from fetal liver progenitor cells, peri- and neonatally. The developmental steps and anatomical sites required for these cells to become mature B-1a cells remain elusive. We recently described a phenotypically distinct transitional B cell subset in the spleen of neonatal mice that generated B-1a cells when adoptively transferred. Read More
Proc Natl Acad Sci U S A 2018 08 2;115(34):E8007-E8016. Epub 2018 Aug 2.
St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY 10065;
Isolated congenital asplenia (ICA) is the only known human developmental defect exclusively affecting a lymphoid organ. In 2013, we showed that private deleterious mutations in the protein-coding region of , encoding ribosomal protein SA, caused ICA by haploinsufficiency with complete penetrance. We reported seven heterozygous protein-coding mutations in 8 of the 23 kindreds studied, including 6 of the 8 multiplex kindreds. Read More
Pediatrics 2018 Sep 1;142(3). Epub 2018 Aug 1.
Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom;
Background: The capsular group B meningococcal vaccine (4CMenB) is recommended for children with complement deficiencies, asplenia, and splenic dysfunction; however, data on the immunogenicity of 4CMenB in these "at-risk" children are missing.
Methods: Participants aged 2 to 17 years in Italy, Spain, Poland, the United Kingdom, and Russia with complement deficiencies, asplenia, or splenic dysfunction received 2 doses of 4CMenB 2 months apart, as did healthy children in the control group. Exogenous and endogenous human complement serum bactericidal activity (SBA) was determined at baseline and 1 month after the second immunization against 4 test strains: H44/76 (assessing vaccine antigen factor H binding protein), 5/99 (Neisserial adhesion A), NZ98/254 (Porin A), and M10713 (Neisserial heparin binding antigen). Read More
Int J Cardiol 2018 Oct;268:100-105
Department of Pediatric Cardiology and Cardiac Surgery, Bambino Gesù Children Hospital and Research Institute, Rome, Italy.
Background: Heterotaxy syndrome (HS) is a group of congenital disorders characterized by abnormal arrangement of thoraco-abdominal organs across the left-right axis of the body, classified as right (RAI) and left atrial isomerism (LAI)·We investigated the long-term survival and phenotypic spectrum in our HS cohort. Results are compared to literature data.
Methods: This is a single centre, observational, both retro and prospective study. Read More
J Pediatr Surg 2018 Jun 25. Epub 2018 Jun 25.
Department of Surgery, Boston Children's Hospital and Harvard Medical School, Boston, MA, United States.
Background: Children who have undergone splenectomy may develop impaired immunologic function and heightened risk of overwhelming postsplenectomy infection. We sought to define the long-term rate of and risk factors for postsplenectomy sepsis.
Methods: We leveraged the Military Health System Data Repository, a nationally representative claims database including >3 million children registered as dependents of members of the United States Armed Services (2005-2014). Read More
Hum Vaccin Immunother 2018 Jul 18:1-6. Epub 2018 Jul 18.
b Monash Infectious Diseases , Monash Health , Melbourne , Australia.
Objective: To evaluate quality of patient knowledge and rates of adherence to guidelines amongst splenectomised patients registered to the Spleen Australia registry.
Method: Registrants recruited for assessment of residual splenic function post-splenectomy also underwent an assessment of quality of knowledge and a review of their long-term management. Eligible patients were ≥ 18 years of age, registered to the Spleen Australia clinical registry and had been splenectomised at least 1 year prior to their visit. Read More
Intern Med 2018 Nov 6;57(22):3329-3332. Epub 2018 Jul 6.
Department of Hematology, NHO Matsumoto Medical Center, Japan.
Asplenia may yield an increased risk of fulminant sepsis with various pathogens. Human infection with Campylobacter fetus is rare, but it often presents with non-gastrointestinal tract infection among immunocompromised individuals. A 55-year-old abattoir worker presented with a fever. Read More
Int J Cardiol 2019 Jan 21;274:117-119. Epub 2018 Jun 21.
Department of Cardiac, Thoracic, and Vascular Sciences, University of Padua, Italy.
Rev Esp Salud Publica 2018 May 11;92. Epub 2018 May 11.
Servicio de Medicina Preventiva y Salud Pública. Hospital Universitario Miguel Servet. Zaragoza. España.
Objective: The quality of health information online is a concern to governments and users. Our objective was to determine the extent to which the information available online regarding meningococcal B vaccine recommendations adhere to the guidelines of the Spanish Ministry of Health.
Methods: Cross-sectional study carried out in April 2017. Read More
Vaccine 2018 06 24;36(26):3876-3881. Epub 2018 Apr 24.
Immunisation, Hepatitis and Blood Safety Department, Public Health England, London, United Kingdom; St. George's University of London, United Kingdom.
The epidemiology of invasive meningococcal disease (IMD) is constantly changing as new strains are introduced into a population and older strains are removed through vaccination, population immunity or natural trends. Consequently, the clinical disease associated with circulating strains may also change over time. In England, IMD incidence has declined from 1. Read More
J Clin Oncol 2018 Jun 17;36(16):1571-1578. Epub 2018 Apr 17.
Brent R. Weil, Arin L. Madenci, and Christopher B. Weldon, Boston Children's Hospital; Brent R. Weil, Arin L. Madenci, Lisa R. Diller, and Christopher B. Weldon, Harvard Medical School; Brent R. Weil, Lisa R. Diller, and Christopher B. Weldon, Dana-Farber Cancer Institute; Arin L. Madenci, Brigham and Women's Hospital, Boston, MA; Qi Liu, University of Alberta, Edmonton, Alberta, Canada; Rebecca M. Howell and Susan A. Smith, The University of Texas MD Anderson Cancer Center, Houston, TX; Todd M. Gibson, Yutaka Yasui, Christopher L. Tinkle, and Gregory T. Armstrong, St Jude Children's Research Hospital, Memphis, TN; Joseph P. Neglia, University of Minnesota, Minneapolis, MN; Wendy M. Leisenring, Fred Hutchinson Cancer Research Center, Seattle, WA; Emily S. Tonorezos and Danielle N. Friedman, Memorial Sloan Kettering Cancer Center, New York; Louis S. Constine, University of Rochester Medical Center, Rochester, NY; and Kevin C. Oeffinger, Duke University, Durham, NC.
Purpose Infection-related outcomes associated with asplenia or impaired splenic function in survivors of childhood cancer remains understudied. Methods Late infection-related mortality was evaluated in 20,026 5-year survivors of childhood cancer (diagnosed < 21 years of age from 1970 to 1999; median age at diagnosis, 7.0 years [range, 0 to 20 years]; median follow-up, 26 years [range, 5 to 44 years]) using cumulative incidence and piecewise-exponential regression models to estimate adjusted relative rates (RRs). Read More
Zhonghua Fu Chan Ke Za Zhi 2018 Mar;53(3):149-154
Department of Obstetrics and Gynecology, Peking University People's Hospital, Beijing 100044, China.
To explore the clinical characteristics of interrupted of the inferior vena cava with azygous continuation and the prognosis. Retrospective analysis of 21 fetuses diagnosed with interrupted inferior vena cava with azygous continuation among 28 567 pregnant women who underwent routine ultrasound scan. The clinical data, ultrasonographic features, genetic information and prognosis were collected. Read More
Vaccine 2018 04 22;36(17):2356-2363. Epub 2018 Mar 22.
GSK, Avenue Fleming 20 (W23), 1300 Wavre, Belgium. Electronic address:
Background: Individuals with functional or anatomic asplenia are at high risk for meningococcal disease. We evaluated the immunogenicity and safety of 1 and 2 doses of the quadrivalent meningococcal serogroups A, C, W, Y tetanus toxoid-conjugate vaccine (MenACWY-TT) in this high-risk population.
Methods: This phase III, open-label, controlled, non-randomized study (NCT01641042) enrolled 1-17-year-olds with impaired splenic activity (high-risk group) and age-matched healthy controls (control group). Read More
J Pediatr Surg 2018 May 8;53(5):973-975. Epub 2018 Feb 8.
Division of General and Thoracic Surgery, Hospital for Sick Children and Department of Surgery, University of Toronto, Toronto, Ontario, Canada. Electronic address:
Background: Laparoscopic partial splenectomy (LPS) theoretically maintains long-term splenic immune function for children with hereditary spherocytosis (HS). Our goal was to review our results after LPS and to determine if specific genetic mutations influence outcome.
Methods: All children with HS undergoing LPS between 2005 and 2016 were reviewed. Read More
JA Clin Rep 2018 12;4(1):16. Epub 2018 Feb 12.
1Department of Anesthesiology, Saitama International Medical Center, 1397-1 Yamane, Hidaka, Saitama Japan.
Background: Heterotaxy syndrome (HS) is characterized by a wide variety of cardiac and extra-cardiac malformations, including pulmonary valve stenosis, interruption of the inferior vena cava, total anomalous pulmonary venous connection (TAPVC), asplenia, polysplenia, intestinal malrotation, and preduodenal portal vein (PDPV). We report the case of a heterotaxic infant with an infracardiac TAPVC and preduodenal portal vein who experienced repetitive hemodynamic instability during urgent laparotomy for duodenal obstruction.
Case Presentation: A 3-day-old boy with HS was planned to undergo urgent laparotomy for duodenal atresia. Read More
Transfusion 2018 04 22;58(4):879-883. Epub 2018 Feb 22.
Cancer and Blood Disorders, Children's Hospitals and Clinics of Minnesota, Minneapolis, Minnesota.
Background: Acute splenic sequestration crisis is a complication of sickle cell disease (SCD) occurring when intrasplenic red blood cell (RBC) sickling prevents blood from leaving the spleen, causing acute splenic enlargement. Although typically seen in young children, it has been reported in older children with hemoglobin (Hb)SC disease, eventually resulting in functional asplenia. Ceftriaxone is a frequently used antibiotic of choice for children with SCD, because of its efficacy against invasive pneumococcal disease. Read More
Clin Infect Dis 2018 Aug;67(4):557-561
School of Public Health and Preventive Medicine, Monash University.
Background: Overwhelming post-splenectomy infection (OPSI) is a serious complication of asplenia. Clinical guidelines recommend numerous measures to reduce the risk of OPSI, but awareness and adherence to preventative measures are generally poor. We aimed to determine whether a registry for asplenic/hyposplenic patients was associated with a reduction in the incidence of infection with encapsulated bacteria. Read More
Am J Case Rep 2018 Feb 19;19:183-186. Epub 2018 Feb 19.
Department of Medicine, Division of Infectious Diseases, Bronx Lebanon Hospital Center, Bronx, NY, USA.
BACKGROUND Cryptococcal meningitis in patients who are seronegative for the human immunodeficiency virus (HIV) and in patients who are splenectomized is rare. This report is an unusual case of meningeal and cerebellar infection due to the encapsulated yeast, Cryptococcus neoformans, which has not previously been associated with asplenia. CASE REPORT A 65-year-old HIV-negative patient with a previous splenectomy, presented with a three-day history of fever, vomiting, and headache. Read More
Circ Cardiovasc Imaging 2018 Feb;11(2):e006917
From the Labatt Family Heart Centre (D.Y., H.N., L.G.-W., M.S., E.J., S.-J.Y.) and Department of Diagnostic Imaging (C.Z.L., L.G.-W., M.S., S.-J.Y.), The Hospital for Sick Children, Toronto, Canada; and Department of Pediatrics, University of Toronto, Canada (L.G.-W., M.S., E.J., S.-J.Y.).
Background: It is advocated that heterotaxy should be segregated into right or left isomerism according to atrial appendage morphology. However, atrial situs determination is often based on the pattern of associated findings rather than on atrial morphology itself, which can be difficult to define. The objective was to assess how often concordant patterns of isomerism classified by atrial appendage morphology, bronchopulmonary pattern, and splenic status are breached using cardiac magnetic resonance or computed tomography. Read More
Methods Mol Biol 2018 ;1733:145-157
Retroviral Genetics Group, Pharmaco-MicroRNA Genomics, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi, Japan.
MicroRNA (miRNA) is the noncoding gene: therefore, the miRNA gene inheritably controls protein gene expression through transcriptional and post-transcriptional levels. Aberrant expression of miRNA genes causes various human diseases, especially cancers. Although cancer is a complex disease, cancer/miRNA implication has yet been grasped from the perspective of miRNA profile in bed side. Read More
Am J Forensic Med Pathol 2018 Jun;39(2):152-156
From the Arkadi M. Rywlin, MD, Department of Pathology and Laboratory Medicine, Mount Sinai Medical Center, Miami Beach, FL.
Sickle cell disease (SCD) manifests itself with vaso-occlusive episodes leading to infarction. Placement of intravascular catheters provides a useful route for management of pain crises as well as other complications. However, catheter misuse is a commonly unrecognized problem, which can have lethal consequences. Read More
Blood 2017 12;130(26):2906
Temple University Hospital.
BMC Infect Dis 2017 12 18;17(1):777. Epub 2017 Dec 18.
Department of Pediatrics, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Background: Isolated congenital asplenia (ICA) is a rare and life-threatening condition that predisposes patients to severe bacterial infections. Most of the reported cases are familial and the mode of inheritance is usually autosomal dominant. Here, we report a case of sporadic isolated asplenia and review the literature while focusing on sporadic cases. Read More
Hematology 2018 Sep 13;23(8):526-530. Epub 2017 Dec 13.
a Faculty of Medicine, Nursing and Health Sciences , Monash University , Clayton , Australia.
Objectives: Asplenia and hyposplenism carry a significant risk of ongoing morbidity and mortality which can be reduced by education, vaccination and antibiotic use. We aimed to assess education and other methods of prevention in a cohort of patients with haemoglobinopathy in a tertiary referral centre, which also had access to a post-splenectomy registry created to reduce post-splenectomy infection risk.
Methods: A standardized questionnaire was used on patients who attended the service for regular therapy. Read More
Rheumatol Int 2018 Feb 8;38(2):239-247. Epub 2017 Nov 8.
Division of Rheumatology, Department of Internal Medicine, Eskişehir Osmangazi University, 26480, Eskisehir, Turkey.
In systemic lupus erythematosus (SLE), the most commonly encountered finding related to platelets is thrombocytopenia whereas thrombocytosis is rarely reported. Our aim here was to reveal the type and the frequency of thrombocytosis in SLE patients along with its causes. Data of patients were evaluated retrospectively. Read More
J Thromb Thrombolysis 2018 Jan;45(1):192-195
Department of Medicine, University of Toronto, 190 Elizabeth Street, R. Fraser Elliott Building, 3-805, Toronto, ON, M5G 2C4, Canada.
More recent immune thrombocytopenia (ITP) treatment strategies enhance platelet production with the use of thrombopoietin receptor agonists (TPO-RA) such as eltrombopag. Patients receiving TPO-RA agents may be at an increased risk of thromboembolism, however the pathophysiology and common underlying risk factors are not well understood. We present the case of a young asplenic woman on eltrombopag for chronic ITP with acute myocardial infarction involving the right coronary artery. Read More
Am J Case Rep 2017 Oct 19;18:1118-1122. Epub 2017 Oct 19.
Department of Medical Education, Henry Ford Hospital, Detroit, MI, USA.
BACKGROUND Isolated congenital asplenia is a poorly understood and rare form of primary immunodeficiency, often associated with life-threatening infections. CASE REPORT We encountered a unique case of a 22-year-old asplenic male who presented with severe iron-deficiency anemia secondary to occult gastrointestinal bleeding since age 15. Our extensive work-up confirmed jejunal arteriovenous malformations as the source of the bleed. Read More
BMC Vet Res 2017 Sep 29;13(1):292. Epub 2017 Sep 29.
Division of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan.
Background: Laterality disorders of the abdominal organs include situs inversus totalis that mirrors the arrangements of all internal organs and heterotaxy syndrome (situs ambiguus) in which the thoracic or abdominal organs are abnormally arranged. Heterotaxy is often accompanied by multiple congenital malformations, and it generally comprises asplenia and polysplenia syndromes. To our knowledge, polysplenia syndrome has been reported in only three cattle, and computerized tomographic (CT) images of these animals were not obtained. Read More
Am J Med Genet A 2017 Nov 12;173(11):3070-3074. Epub 2017 Sep 12.
Molecular Genetics of Development Laboratory, Department of Biological Sciences and BioMed Research Center, Faculty of Sciences, University of Quebec at Montreal, Montreal, Quebec.
Isolated congenital diaphragmatic hernia is often a sporadic event with a low recurrence risk. However, underlying genetic etiologies, such as chromosome anomalies or single gene disorders, are identified in a small number of individuals. We describe two fetuses with a unique pattern of multiple congenital anomalies, including diaphragmatic hernia, short bowel and asplenia, born to first-cousin parents. Read More
Vaccine 2017 09 31;35(40):5331-5338. Epub 2017 Aug 31.
GSK, 20, Avenue Fleming, B-1300 Wavre, Belgium. Electronic address:
Background: Immunization with pneumococcal vaccines is an important prophylactic strategy for children with asplenia or splenic dysfunction, who are at high risk of bacterial infections (including S. pneumoniae). This study aimed to assess immunogenicity and safety of pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV, GSK) in this at-risk population. Read More
Pediatr Infect Dis J 2018 Apr;37(4):e108-e110
From the Department of Pediatrics, Global Child Health Residency Program, Baylor College of Medicine, Houston, Texas, Division of Hospital Medicine, Department of Pediatrics, University of Alabama at Birmingham, and Division of Infectious Disease, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama.
The post Hib-vaccine era has resulted in increased cases of invasive, non-Hib, Haemophilus influenzae infections. One of the encapsulated species, type a, displays the most similarity in virulence to type b. Our patient, a fully vaccinated 4-year-old female, with newly diagnosed asplenia in the setting of heterotaxy, had a prolonged hospital course with disseminated Haemophilus influenzae type a infection. Read More
Clin Pediatr (Phila) 2018 May 25;57(5):597-599. Epub 2017 Aug 25.
1 Stead Family Children's Hospital, University of Iowa, Iowa City, IA, USA.
Ultrasound Obstet Gynecol 2017 Oct 14;50(4):476-491. Epub 2017 Aug 14.
Perinatology Research Branch, Program for Perinatal Research and Obstetrics, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD and Detroit, MI, USA.
Objective: To evaluate the performance of color and bidirectional power Doppler ultrasound combined with Fetal Intelligent Navigation Echocardiography (FINE) in examining the fetal heart.
Methods: A prospective cohort study was conducted of fetuses in the second and third trimesters with a normal heart or with congenital heart disease (CHD). One or more spatiotemporal image correlation (STIC) volume datasets, combined with color or bidirectional power Doppler (S-flow) imaging, were acquired in the apical four-chamber view. Read More
Congenit Heart Dis 2017 Dec 25;12(6):756-761. Epub 2017 Jul 25.
Division of Pediatric Cardiology, Department of Pediatrics, Cincinnati Children's Hospital, Cincinnati, Ohio, USA.
Introduction: In 2012, the American College of Cardiology's (ACC) Adult Congenital and Pediatric Cardiology Council established a program to develop quality metrics to guide ambulatory practices for pediatric cardiology. The council chose five areas on which to focus their efforts; chest pain, Kawasaki Disease, tetralogy of Fallot, transposition of the great arteries after arterial switch, and infection prevention. Here, we sought to describe the process, evaluation, and results of the Infection Prevention Committee's metric design process. Read More
Am J Trop Med Hyg 2017 Oct 19;97(4):1218-1225. Epub 2017 Jul 19.
Marshfield Clinic Health System, Minocqua, Wisconsin.
Babesiosis is an emerging tick-borne disease transmitted by the hard tick , which also transmits Lyme disease. Better gradation of prognostic indicators are needed to determine which patients may develop serious complications requiring hospitalization, and to provide early guidance on appropriate therapy. In this study, we evaluated 128 patients with smear or real time polymerase chain reaction-confirmed infections over a period of 16 years. Read More
J Am Assoc Nurse Pract 2017 Oct 19;29(10):612-617. Epub 2017 Jul 19.
University of Louisville Hospital, Louisville, Kentucky.
Background And Purpose: Patients undergoing splenectomy for trauma are at life-long risk for rapidly progressive septicemia. The purpose of this study was to investigate long-term patient understanding and follow-up with recommendations regarding their asplenia.
Methods: Patients undergoing splenectomy for trauma January 2010-December 2014 were analyzed. Read More
Infect Dis (Lond) 2017 Nov - Dec;49(11-12):809-816. Epub 2017 Jul 6.
e Department of Clinical and Experimental Medicine , Linköping University , Linköping , Sweden.
Background: Neoehrlichiosis is an infectious disease caused by the tick-borne bacterium "Candidatus Neoehrlichia mikurensis". Splenectomy and rituximab therapies are risk factors for severe neoehrlichiosis. Our aim was to examine if neoehrlichiosis patients had low levels of natural IgM antibodies and/or were hypogammaglobulinemic, and if such deficiencies were associated with asplenia and vascular complications. Read More
BMC Public Health 2017 06 29;17(1):610. Epub 2017 Jun 29.
Primary Health Care Service "Camp de Tarragona", Institut Catala de la Salut, Rambla Nova 124, D,1°A, 43001, Tarragona, Spain.
Background: Updated population-based data on the frequency and distribution of risk factors for pneumococcal disease is scarce. This study investigated the prevalence of distinct comorbidities and underlying risk conditions related to an increasing risk of pneumococcal disease among Catalonian middle-aged and older adults.
Methods: Cross-sectional population-based study including 2,033,465 individuals aged 50 years or older registered at 01/01/2015 in the Catalonian Health Institute (Catalonia, Spain). Read More