Role of Bi-Weekly Serum Galactomannan Screening for the Diagnosis of Invasive Aspergillosis in Hematologic Cancer Patients.
- Jade Couchepin,
- Anne-Sophie Brunel,
- Katia Jaton,
- Pascal Meylan,
- Pierre-Yves Bochud,
- Frédéric Lamoth
Mycoses 2018 Feb 17. Epub 2018 Feb 17.
Infectious Diseases Service Department of Medicine, Lausanne University Hospital, Lausanne, Switzerland.
Invasive aspergillosis (IA) is a life-threatening infection affecting hematologic cancer patients with chemotherapy-induced neutropenia. The diagnosis of IA often relies on the detection of galactomannan (GM) in serum or bronchoalveolar lavage fluid (BAL). Bi-weekly serum GM screening has been proposed for a preemptive therapeutic approach of IA in patients not receiving mold-active prophylaxis. Read More