472 results match your criteria Asian journal of transfusion science[Journal]


Need for plateletpheresis procedure with voluntary regular apheresis donors: An experience.

Asian J Transfus Sci 2018 Jul-Dec;12(2):183-184

Indian Red Cross Society, Ahmedabad, Gujarat, India.

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http://dx.doi.org/10.4103/ajts.AJTS_127_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327769PMC
January 2019

Para-Bombay phenotype: A case report from a tertiary care hospital from South Gujarat.

Asian J Transfus Sci 2018 Jul-Dec;12(2):180-182

Department of Transfusion Medicine, ICMR- National Institute of Immunohaematology, Mumbai, Maharashtra, India.

The blood specimen of a 30-year-old male donor showing a discrepancy in cell and serum grouping was targeted for detailed study at the blood bank at tertiary care hospital in South Gujarat. Forward grouping showed group as "O" RhD positive and reverse grouping as group "A." Further testing confirmed that the individual's blood group was para-Bombay A (para-AH). Read More

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http://dx.doi.org/10.4103/ajts.AJTS_151_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327760PMC
January 2019

Severe ABO hemolytic disease of fetus and newborn requiring blood exchange transfusion.

Asian J Transfus Sci 2018 Jul-Dec;12(2):176-179

Department of Transfusion Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

ABO incompatibility and other alloantibodies have emerged as a significant cause of hemolytic disease of fetus and newborn (HDFN), leading to neonatal morbidity and mortality. We report three cases of severe ABO-HDFN where blood exchange transfusions (ETs) were required in neonates with hyperbilirubinemia. Blood grouping (ABO/RhD) was performed using conventional tube technique. Read More

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http://dx.doi.org/10.4103/ajts.AJTS_106_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327763PMC
January 2019
1 Read

Therapeutic plasma exchange as a life-saving therapy in a suspected case of autoimmune encephalitis: A case report from a tertiary health-care center.

Asian J Transfus Sci 2018 Jul-Dec;12(2):173-175

Department of Neurology, Jaypee Hospital, Noida, Uttar Pradesh, India.

In half of the suspected autoimmune encephalitis (AIE) patients, no antibodies are identified despite extensive investigation. Therapeutic plasma exchange (TPE) is a potential first-line therapy for various subtypes of AIE. Here, we present a case of autoantibody-negative-suspected AIE, managed successfully with TPE after patient showed no response to steroids. Read More

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http://dx.doi.org/10.4103/ajts.AJTS_112_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327764PMC
January 2019
10 Reads

Real eyes realizes real lies: A case report and review of nuisance antibodies in immunohematology.

Asian J Transfus Sci 2018 Jul-Dec;12(2):169-172

Department of Immunohematology and Blood Transfusion, Kasturba Medical College, Manipal Academy of Higher Educations, Manipal, Karnataka, India.

Detection of nonspecific antibodies unrelated to blood group antigen that causes nuisance in pretransfusion testing is a rare event. Their interpretation is often made only after the exclusion of all possible clinically significant antibodies and results in the unnecessary expenditure of reagents and human resources. We report one such nuisance antibody detected in an antenatal female that showed pan reaction with antibody screening and identification panel red cells including auto control but was compatible with group-specific donor units. Read More

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http://dx.doi.org/10.4103/ajts.AJTS_100_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327759PMC
January 2019
1 Read

Comparative evaluation of enzyme-linked immunosorbent assay with rapid plasma reagin for screening of syphilis in blood donors.

Asian J Transfus Sci 2018 Jul-Dec;12(2):165-168

Department of Transfusion Medicine, PGIMER, Chandigarh, India.

World Health Organization (WHO) recommends screening of syphilis in low prevalence populations of blood donors by treponemal tests like enzyme-linked immunosorbent assay (ELISA), whereas in India screening is done by rapid plasma reagin (RPR). The present pilot study evaluated the performance of ELISA compared to RPR, keeping hemagglutination assay as a reference test. ELISA was equally sensitive (100%), more specific (56. Read More

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http://www.ajts.org/text.asp?2018/12/2/165/247981
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http://dx.doi.org/10.4103/ajts.AJTS_126_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327766PMC
January 2019
1 Read

A positive complement dependent cytotoxicity immunoglobulin G crossmatch due to auto-antibodies with a negative luminex bead assays in a renal transplant recipient: A Diagnostic dilemma.

Asian J Transfus Sci 2018 Jul-Dec;12(2):160-164

Department of Transfusion Medicine and Immunology, Indraprastha Apollo Hospitals, New Delhi, India.

Transplant recipients are always at a risk of developing anti-human leukocyte antigen (HLA) antibodies due to prior sensitizing events such as blood transfusions, multiple pregnancies, or transplantation. Unexpected positive outcomes can be seen in complement dependent cytotoxicity (CDC) based assays due to underlying autoimmune disorders or pharmacological treatment (rituximab/intravenous immunoglobulin/anti-thymocyte globulin administration), therefore, limiting its value. CDC based assay results strongly depend on the vitality of the donor lymphocytes, highlighting another major limitation of this assay. Read More

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http://dx.doi.org/10.4103/ajts.AJTS_95_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327756PMC
January 2019
3 Reads

Manual red cell exchange transfusion to avert sickle cell related complications.

Asian J Transfus Sci 2018 Jul-Dec;12(2):157-159

Department of Immunohematology and Blood Transfusion, MGM Medical College and Hospital, Mumbai, Maharashtra, India.

Sickle cell-beta thalassemia is a double heterozygous state. Red cell exchange (RCE) transfusion reduces the concentration of sickle cells without increasing the hematocrit or whole-blood viscosity. It can be performed manually or by erythrocytapheresis. Read More

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http://www.ajts.org/text.asp?2018/12/2/157/247983
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http://dx.doi.org/10.4103/ajts.AJTS_128_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327770PMC
January 2019
10 Reads

Severe hypertriglyceridemia-induced pancreatitis successfully managed with therapeutic plasma exchange: Report from India.

Asian J Transfus Sci 2018 Jul-Dec;12(2):154-156

Department of Transfusion Medicine, Medanta - The Medicity, Gurgaon, Haryana, India.

Hypertriglyceridemia (HTG) is the third most significant risk factor for acute pancreatitis after gallstones and alcohol. Therapeutic plasma exchange (TPE) has been considered a possible treatment for HTG-induced pancreatitis, especially in severe and refractory cases. Here, we report one such clinical experience with a patient of severe HTG-induced pancreatitis. Read More

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http://dx.doi.org/10.4103/ajts.AJTS_86_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327775PMC
January 2019
1 Read

Evaluation of bacterial inactivation in random donor platelets and single-donor apheresis platelets by the INTERCEPT blood system.

Asian J Transfus Sci 2018 Jul-Dec;12(2):146-153

Hemogenomics Pvt Ltd., Bangalore, Karnataka, India.

Background: Blood transfusion of contaminated components is a potential source of sepsis by a wide range of known and unknown pathogens. Collection mechanism and storage conditions of platelets make them vulnerable for bacterial contamination. Several interventions aim to reduce the transfusion of contaminated platelet units; however, data suggest that contaminated platelet transfusion remains very common. Read More

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http://dx.doi.org/10.4103/ajts.AJTS_87_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327773PMC
January 2019
1 Read

Audit and education: Role in safe transfusion practice.

Asian J Transfus Sci 2018 Jul-Dec;12(2):141-145

Department of Transfusion Medicine, Max Super-speciality Hospital, Shalimar Bagh, New Delhi, India.

Background: Auditing and education are the tools for improvement in the transfusion practices. Clinicians are not providing patient's demographic data and medical history to the blood bank that required transfusion. This missing information in blood request forms can lead to transfusion reactions to the patient. Read More

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http://dx.doi.org/10.4103/ajts.AJTS_135_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327772PMC
January 2019
1 Read

Adding to platelet safety and life: Platelet additive solutions.

Asian J Transfus Sci 2018 Jul-Dec;12(2):136-140

Department of Transfusion Medicine, Rotary Bangalore TTK Blood Bank, Bangalore Medical Services Trust, Bengaluru, Karnataka, India.

Background: Platelet additive solutions (PAS) are crystalloid nutrient media used in place of plasma for platelet storage. They replace 60%-70% of plasma in platelet components, so the amount of storage plasma can be decreased. Platelets in PAS have lower risk for allergic transfusion reactions with equivalent clinical efficacy for controlling bleeding. Read More

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http://www.ajts.org/text.asp?2018/12/2/136/247986
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http://dx.doi.org/10.4103/ajts.AJTS_150_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327774PMC
January 2019
13 Reads

Therapeutic plasma exchange for pediatric nonrenal disease indications and outcomes: A single-center experience.

Asian J Transfus Sci 2018 Jul-Dec;12(2):127-135

Department of Paediatrics, Apollo Children's Hospitals, Chennai, Tamil Nadu, India.

Introduction: Outcome data in pediatric plasma exchange, especially in nonrenal indications are scarce. We aimed to evaluate its role and outcome in our patients.

Subjects And Methods: A retrospective study of children admitted in the year 2016 to the Pediatric Intensive Care Unit requiring plasma exchange for nonrenal indications was undertaken. Read More

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http://dx.doi.org/10.4103/ajts.AJTS_123_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327757PMC
January 2019
6 Reads

Intra- and inter-model reliability of Hemocue Hb 201+ and HemoCue Hb 301 devices.

Asian J Transfus Sci 2018 Jul-Dec;12(2):123-126

All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.

Aim: The study intended to estimate the intra- and inter-model reliability and agreement between the HemoCue Models 201+ and 301 in a blood bank donor screening setting.

Materials And Methods: Venous blood samples from 115 blood donors were analyzed by two Hemocue 201+ instruments and two HemoCue 301 instruments. The Lin's concordance correlation coefficient (CCC) as well as the Bland-Altman limits of agreement was measured. Read More

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http://dx.doi.org/10.4103/ajts.AJTS_119_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327767PMC
January 2019

Outcome of 51 autologous peripheral blood stem cell transplants after uncontrolled-rate freezing ("dump freezing") using -80°C mechanical freezer.

Asian J Transfus Sci 2018 Jul-Dec;12(2):117-122

Department of Hematology, BLK Super Speciality Hospital, New Delhi, India.

Background And Objective: Controlled-rate freezing is a complicated, expensive, and time-consuming procedure. Therefore, there is a growing interest in uncontrolled-rate freezing (UCF) with -80°C mechanical freezers for cryopreservation of hematopoietic stem cells. This is a retrospective analysis of efficiency of UCF and outcome of autologous peripheral hematopoietic stem cell (PBSC) transplants at our center from December 2011 to June 2016. Read More

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http://dx.doi.org/10.4103/ajts.AJTS_42_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327762PMC
January 2019
1 Read

Experience of hepatitis C virus seroprevalence and its genomic diversity among transfusion-dependent thalassemia patients in a transfusion center.

Asian J Transfus Sci 2018 Jul-Dec;12(2):112-116

ICMR Virus Unit, I.D. and B.G. Hospital, Kolkata, West Bengal, India.

Introduction: One of the most common blood-borne transfusion-transmitted diseases is hepatitis C. Patients with a history of multiple blood transfusions are significantly at a greater risk of infection by contaminated blood and blood products. Beta thalassemia major is one such condition where repeated blood transfusions are required for patient management. Read More

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http://dx.doi.org/10.4103/ajts.AJTS_73_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327771PMC
January 2019
2 Reads

Regenerative efficacy of therapeutic quality platelet-rich plasma injections versus phonophoresis with kinesiotaping for the treatment of chronic plantar fasciitis: A prospective randomized pilot study.

Asian J Transfus Sci 2018 Jul-Dec;12(2):105-111

Department of Transfusion Medicine, PGIMER, Chandigargh, India.

Background: Plantar fasciitis (PF) a common chronic musculoskeletal pain routinely diagnosed and treated in rehabilitation practices. When conservative management fails in this degenerative disease, local injections of corticosteroids, platelet rich plasma (PRP), botulinum toxin, extracorporeal shockwave therapy, surgical release are used. In our prospective randomized pilot study we compared the regenerative efficacy of Platelet Rich Plasma vs Kinesiotaping with phonophoresis who were resistant to conservative management of PF. Read More

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http://www.ajts.org/text.asp?2018/12/2/105/247989
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http://dx.doi.org/10.4103/ajts.AJTS_48_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327765PMC
January 2019
3 Reads

Immunohematological and clinical characterizations of mixed autoimmune hemolytic anemia.

Asian J Transfus Sci 2018 Jul-Dec;12(2):99-104

Department of Transfusion Medicine, Apollo Gleneagles Hospitals, Kolkata, West Bengal, India.

Background And Aim: Patients with warm autoimmune hemolytic anemia (AIHA) may carry immunoglobulin (Ig) M antibodies that react at room temperature and are nonpathological, but few may have cold agglutinins that react at or above 30°C and are referred to as "mixed" AIHA (MAIHA). Here, we present our experience on characterizing MAIHA both clinically and serologically.

Materials And Methods: Out of 134 AIHA patients, 13 diagnosed as MAIHA were subjected to detailed immunohematological characterization. Read More

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http://dx.doi.org/10.4103/ajts.AJTS_105_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327768PMC
January 2019
2 Reads

Use of infusion pump for intrauterine transfusion: An effective hands-free transfusion circuit.

Asian J Transfus Sci 2018 Jul-Dec;12(2):97-98

Department of Immunohematology and Blood Transfusion, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.

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http://dx.doi.org/10.4103/ajts.AJTS_91_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327761PMC
January 2019

AJTS and it's Legacy of Knowledge.

Authors:
Jayashree Sharma

Asian J Transfus Sci 2018 Jul-Dec;12(2):95-96

Professor and Head, Department of Transfusion Medicine, Seth GS Medical College and KEM Hospital, Parel, Mumbai - 12, Maharashtra, India.

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http://dx.doi.org/10.4103/ajts.AJTS_129_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327758PMC
January 2019

A curious case of thick white slick in a blood bag.

Asian J Transfus Sci 2018 Jan-Jun;12(1):93-94

Department of Transfusion Medicine, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

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http://dx.doi.org/10.4103/ajts.AJTS_22_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850708PMC

Detection of antibodies to co-trimoxazole (preservative drug) interfering with routine red cell antibody screening.

Asian J Transfus Sci 2018 Jan-Jun;12(1):89-92

Department of Transfusion Medicine, Global Health City, Chennai, Tamil Nadu, India.

Drug-dependent antibodies can rarely cause interference in pretransfusion antibody screening. The diluents for commercial reagent red blood cells contain different antibiotics, such as chloramphenicol, neomycin sulfate, and gentamycin as a preservative. The presence of antibodies to a given drug in patient may lead to positive results when performing antibody identification. Read More

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http://dx.doi.org/10.4103/ajts.AJTS_119_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850707PMC

Hemophagocytic lymphohistiocytosis in an infant with multiple triggers!!

Asian J Transfus Sci 2018 Jan-Jun;12(1):85-88

Department of Pediatrics, Chacha Nehru Bal Chikitsalaya, New Delhi, India.

Hemophagocytic lymphohistiocytosis (HLH) is a disorder of immune dysregulation secondary to a massive unregulated cytokine storm and its downstream consequences. HLH is being increasingly recognized as a cause of pyrexia of unknown origin, unexplained cytopenias, and hepatic dysfunction. However, this potentially treatable condition is often missed due to lack of suspicion, variable, and nonspecific presentations, inability to fulfil all the diagnostic criteria and availability of diagnostic tests in resource limited settings. Read More

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http://dx.doi.org/10.4103/ajts.AJTS_142_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850706PMC
March 2018
2 Reads

Anti Kp alloantibody: Development of a rare alloantibody in a non-Hodgkin's lymphoma patient of Indian origin.

Asian J Transfus Sci 2018 Jan-Jun;12(1):81-84

Department of Transfusion Medicine, Sri Balaji Action Medical Institute, New Delhi, India.

The Kell blood group system is complex, contains many antigens, highly immunogenic, and potent in triggering immune reactions. Antibodies to Kell blood group system are the most common immune red cell antibodies, following ABO and Rh. However, among the anti-Kell antibodies; anti-Kp is extremely rare. Read More

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http://dx.doi.org/10.4103/ajts.AJTS_23_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850705PMC

Jehovah's Witness and consent for blood transfusion in a child: The Indian scenario.

Asian J Transfus Sci 2018 Jan-Jun;12(1):78-80

Department of Pediatric Oncology, Regional Cancer Centre, Thiruvananthapuram, Kerala, India.

In India, the clinical guidelines and laws governing consent for blood transfusion in a minor are meager and vague. In an elective situation, whether the parents can make a decision for the child on his/her behalf or whether the doctor has the right to make the decision in the best interests of the child is not clear. We present the case scenario of a child belonging to Jehovah's Witness denomination diagnosed with Burkitt lymphoma. Read More

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http://dx.doi.org/10.4103/ajts.AJTS_50_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850703PMC

A rare case of hemolytic disease of newborn due to weak D (D unknown) antigen in child.

Asian J Transfus Sci 2018 Jan-Jun;12(1):75-77

Department of Paediatrics, SMS Medical College and Attached J K Lon Hospital, Jaipur, Rajasthan, India.

We are reporting a rare case of hemolytic disease of newborn with weak D antigen in child. A 3 order male child of GPA mother was admitted at 8 h of life with jaundice. Blood group of both mother and child were A Rh D negative. Read More

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http://dx.doi.org/10.4103/ajts.AJTS_21_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850702PMC

Relationship between T2* magnetic resonance imaging-derived liver and heart iron content and serum ferritin levels in transfusion-dependent thalassemic children.

Asian J Transfus Sci 2018 Jan-Jun;12(1):69-74

Department of Pediatrics, Dr S N Medical College, Jodhpur, Rajasthan, India.

Context: T2* magnetic resonance imaging (MRI) is being increasingly used for the assessment of organ iron content in thalassemics, but cost is a major prohibitive factor for repeated measurements. If serum ferritin correlates well with the T2* MRI liver and heart, it will be economical and more simple tool to assess organ iron deposition.

Aims: The aim of this study was to find out the relationship between serum ferritin level and T2* MRI-derived liver and heart iron content in transfusion-dependent thalassemic children. Read More

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http://dx.doi.org/10.4103/ajts.AJTS_3_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850701PMC
March 2018
6 Reads

Heterogeneity of O blood group in India: Peeping through the window of molecular biology.

Asian J Transfus Sci 2018 Jan-Jun;12(1):62-68

Department of Transfusion Medicine, National Institute of Immunohaematology, Indian Council of Medical Research, Mumbai, Maharashtra, India.

Background: Molecular genotyping of ABO blood group system has identified more than 60 "O" group alleles based on the single-nucleotide polymorphisms present in the ABO gene. Heterogeneity of O group alleles has been observed in various countries from South America, Europe, Middle East, and Asia. India is a vast country with more than 1300 million population which is divided into various ethnic and tribal groups. Read More

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http://dx.doi.org/10.4103/ajts.AJTS_12_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850700PMC
March 2018
2 Reads

Effect of plasma component transfusion on conventional coagulation screening tests.

Asian J Transfus Sci 2018 Jan-Jun;12(1):57-61

Department of Immunohematology and Blood Transfusion, Kasturba Medical College, Manipal, Karnataka, India.

Background: Conventional coagulation screening tests such as Prothrombin time, International normalized ratio (INR) and activated partial thromboplastin time are often used to predict bleeding in various clinical situations. We aimed to observe the effect of Fresh-frozen plasma (FFP) on these parameters.

Methods: Patients' demographics, pre- and post-transfusion coagulation parameters were noted to assess the level of correction. Read More

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http://dx.doi.org/10.4103/ajts.AJTS_24_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850699PMC
March 2018
2 Reads

An approach to incompatible cross-matched red cells: Our experience in a major regional blood transfusion center at Kolkata, Eastern India.

Asian J Transfus Sci 2018 Jan-Jun;12(1):51-56

Department of Immunohaematology and Blood Transfusion, Kolkata Medical College, Kolkata, West Bengal, India.

Introduction: With the increased utilization of immunohematology (IH) analyzers in the transfusion medicine, type, and screen policy is the method of choice. Still, the importance of routine crossmatching could not be overruled. Here, we tried to understand the clinical conditions and safety of red cell transfusion and their outcomes. Read More

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http://dx.doi.org/10.4103/ajts.AJTS_157_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850698PMC
March 2018
1 Read

Identification of iron status of blood donors by using low hemoglobin density and microcytic anemia factor.

Asian J Transfus Sci 2018 Jan-Jun;12(1):46-50

Department of Transfusion Medicine, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Background: Two new parameters low hemoglobin density (LHD) and microcytic anemia factor (Maf) have been used by Beckman-Coulter LH series analyzers as an easy screening tool for the early detection of iron deficiency. The main objective of this study was to assess if LHD and Maf could be used for assessment of iron status in blood donors and also to establish a cut-off for these two parameters at which a tentative iron deficiency could be reported conclusively.

Materials And Methods: LHD% and Maf could be calculated by knowing mean cell hemoglobin (Hb) concentration, Hb, and mean cellular volume and we used SPSS in calculating LHD and Maf from these parameters. Read More

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http://dx.doi.org/10.4103/ajts.AJTS_30_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850697PMC

Advantages of type and screen policy: Perspective from a developing country!

Asian J Transfus Sci 2018 Jan-Jun;12(1):42-45

Department of Transfusion Medicine, Medanta - The Medicity, Gurgaon, Haryana, India.

Introduction: The authors' center recently changed their pretransfusion testing protocol from "conventional" type and screen (TS) with anti-human globulin (AHG) crossmatch (Policy A) to TS with immediate-spin (IS) crossmatch (Policy B). Red blood cell (RBC) units were issued after compatible IS crossmatch as and when required instead of AHG crossmatch. This study was conducted to compare the effects of change of policy from A to B over 1-year period on crossmatch-to-transfusion (C/T) ratio, RBC issue turnaround time (TAT), outdating of RBC, man-hours consumption, and monetary savings. Read More

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http://dx.doi.org/10.4103/ajts.AJTS_31_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850696PMC
March 2018
3 Reads

Transfusion support in preterm neonates <1500 g and/or <32 weeks in a tertiary care center: A descriptive study.

Asian J Transfus Sci 2018 Jan-Jun;12(1):34-41

Department of Neonatology, Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, India.

Background: Lack of recent studies focusing on indications, pattern, and benefits of transfusions in low birth weight (B.Wt) and low gestational age (GA) preterm neonates prompted us to undertake this study.

Aim: To estimate the transfusion requirements and outcomes in preterm neonates <1500 g and/or <32 weeks. Read More

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http://dx.doi.org/10.4103/ajts.AJTS_148_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850695PMC
March 2018
2 Reads

Assessment of bedside transfusion practices at a tertiary care center: A step closer to controlling the chaos.

Asian J Transfus Sci 2018 Jan-Jun;12(1):27-33

Department of Transfusion Medicine, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Background: Blood transfusion chain can be divided into three phases: preanalytical (patient bedside), analytical (steps done at transfusion services), and postanalytical (bedside). Majority (~70%) of events due to blood transfusion have been attributed to errors in bedside blood administration practices. Survey of bedside transfusion practices (pre-analytical and post analytical phase) was done to assess awareness and compliance to guidelines regarding requisition and administration of blood components. Read More

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http://www.ajts.org/text.asp?2018/12/1/27/225687
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http://dx.doi.org/10.4103/ajts.AJTS_29_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850694PMC
March 2018
3 Reads

Human immunodeficiency virus/acquired immune deficiency syndrome: A survey on the knowledge, attitude, and practice among medical professionals at a tertiary health-care institution in Uttarakhand, India.

Asian J Transfus Sci 2018 Jan-Jun;12(1):21-26

Professor & Head, Department Pathology, Himalayan Institute of Medical Sciences, Dehradun, Uttarakhand, India.

Introduction: Health-care professionals are trained health-care providers who occupy a potential vanguard position in human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS) prevention programs and the management of AIDS patients. This study was performed to assess HIV/AIDS-related knowledge, attitude, and practice (KAP) and perceptions among health-care professionals at a tertiary health-care institution in Uttarakhand, India, and to identify the target group where more education on HIV is needed.

Materials And Methods: A cross-sectional KAP survey was conducted among five groups comprising consultants, residents, medical students, laboratory technicians, and nurses. Read More

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http://www.ajts.org/text.asp?2018/12/1/21/225679
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http://dx.doi.org/10.4103/ajts.AJTS_147_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850693PMC
March 2018
6 Reads

Prevalence of irregular red cell antibody in healthy blood donors attending a tertiary care hospital in North India.

Asian J Transfus Sci 2018 Jan-Jun;12(1):17-20

Department of Transfusion Medicine, Institution Indraprastha Apollo Hospitals, New Delhi, India.

Background: Alloantibodies may be detected in blood donors who have either been transfused previously or female donors with previous obstetric events. These antibodies can occasionally cause severe transfusion reaction, if a large amount of plasma or whole blood is transfused, as in massive transfusions and pediatric patients.

Aims: The present study aims to assess the prevalence of red cell antibodies in healthy blood donors at a tertiary care hospital-based blood bank in India. Read More

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http://www.ajts.org/text.asp?2018/12/1/17/225692
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http://dx.doi.org/10.4103/ajts.AJTS_4_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850692PMC
March 2018
6 Reads

First Indian initiative for preparation of low-titer group "O" single-donor platelets with platelet additive solution.

Asian J Transfus Sci 2018 Jan-Jun;12(1):10-16

Department of Transfusion Medicine, Tata Memorial Hospital, Mumbai, Maharashtra, India.

Background: Guidelines recommend ABO-identical platelet (PLT) transfusions. Hemolytic reactions after a minor ABO-incompatible PLT transfusion have escalated due to single-donor platelets (SDP) containing ABO-incompatible plasma. Avoiding such events by examining titers or performing plasma reduction is cumbersome. Read More

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http://www.ajts.org/text.asp?2018/12/1/10/225682
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http://dx.doi.org/10.4103/ajts.AJTS_2_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850691PMC
March 2018
5 Reads

Unconjugated hyperbilirubinemia in a blood donor: Chance finding due to unusual plasma discoloration.

Asian J Transfus Sci 2018 Jan-Jun;12(1):8-9

Department of Transfusion Medicine, SGPGIMS, Lucknow, Uttar Pradesh, India.

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http://dx.doi.org/10.4103/ajts.AJTS_34_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850704PMC
March 2018
1 Read

Hello…. there is a blob of quark in my cryo bag!!

Asian J Transfus Sci 2017 Jul-Dec;11(2):215-216

Department of Transfusion Medicine, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

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http://dx.doi.org/10.4103/0973-6247.214351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613438PMC
October 2017

Adding up the evidence: Trigger for prophylactic plasma transfusion.

Asian J Transfus Sci 2017 Jul-Dec;11(2):214-215

Department of Immunohematology and Blood Transfusion, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.

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http://dx.doi.org/10.4103/ajts.AJTS_63_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613437PMC
October 2017
1 Read

HIV risk associated with nucleic acid testing tested seronegative blood donation where the donor was not preassessed for the risk.

Asian J Transfus Sci 2017 Jul-Dec;11(2):213-214

Surat Raktadan Kendra and Research Centre, Surat, Gujarat, India.

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http://dx.doi.org/10.4103/ajts.AJTS_136_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613436PMC
October 2017
14 Reads

Out of the blue: Blue blood.!

Asian J Transfus Sci 2017 Jul-Dec;11(2):212

Department of Transfusion Medicine, Jawaharlal Institute of Postgraduate Medical Education, Puducherry, India.

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http://dx.doi.org/10.4103/ajts.AJTS_75_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613435PMC
October 2017
3 Reads

Interference of daratumumab with pretransfusion testing, mimicking a high-titer, low avidity like antibody.

Asian J Transfus Sci 2017 Jul-Dec;11(2):209-211

Department of Laboratory Medicine, Division of Transfusion and Transplantation, National Taiwan University Hospital, Taipei, Taiwan.

Daratumumab is a monoclonal immunoglobulin against CD38 and has been approved for treating patients with refractory multiple myeloma. The presence of daratumumab in the sera can interfere with pretransfusion testing due to the weakly expression of CD38 on red cells. The reactivity could be mistaken as autoantibody (if autocontrol is positive) or alloantibody (if autocontrol is negative). Read More

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http://dx.doi.org/10.4103/0973-6247.214358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613434PMC
October 2017
56 Reads

Daily plasma exchange in severe Guillain-Barré syndrome helps in early weaning from ventilator: A lesson from a case.

Asian J Transfus Sci 2017 Jul-Dec;11(2):206-208

Department of Transfusion Medicine and Blood Bank, AIIMS, Jodhpur, Rajasthan, India.

Intravenous immunoglobulin (IVIG) and therapeutic plasma exchange (TPE) are well-known therapeutic modalities in Guillain-Barré syndrome (GBS). In developing countries like India, where plasma-derived products (IVIG) are not easily available, and affordable TPE is preferred. Here, we reported a case of severe GBS, who was treated with daily plasma exchange (PLEX) rather than recommended alternate day schedule. Read More

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http://www.ajts.org/text.asp?2017/11/2/206/214346
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http://dx.doi.org/10.4103/0973-6247.214346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613433PMC
October 2017
56 Reads

Acute respiratory distress syndrome in a neonate due to possible transfusion-related acute lung injury.

Asian J Transfus Sci 2017 Jul-Dec;11(2):203-205

Department of Pediatrics, PGIMER and RML Hospital, New Delhi, India.

Transfusion-related acute lung injury (TRALI) is a potentially life-threatening complication of blood component transfusion. It is relatively underdiagnosed entity in neonates with scant literature. We report a case of TRALI in a preterm neonate developing acute respiratory distress within 6 h of blood product transfusion in the absence of preexisting lung disease. Read More

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http://dx.doi.org/10.4103/ajts.AJTS_120_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613432PMC
October 2017
11 Reads

Coinheritance of hemoglobin D-Punjab and β-thalassemia 3.4 kb deletion in a Thai girl.

Asian J Transfus Sci 2017 Jul-Dec;11(2):199-202

Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.

Hemoglobin (Hb) D. Punjab [β121(GH4) Glu→Gln; HBB: C.364G>C] and β-thalassemia 3. Read More

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http://www.ajts.org/text.asp?2017/11/2/199/214334
Publisher Site
http://dx.doi.org/10.4103/ajts.AJTS_117_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613431PMC
October 2017
2 Reads

Autoimmune hemolytic anemia caused by anti "e": A challenge: A case report with review of literature.

Asian J Transfus Sci 2017 Jul-Dec;11(2):195-198

Department of Pathology, Lady Hardinge Medical College and Associated Hospitals, Shaheed Bhagat Singh Marg, New Delhi, India.

Autoimmune hemolytic anemia (AIHA) is featured by short red cell survival due to autoantibodies. AIHA caused by anti 'e' is a tough clinical situation as antigen 'e' is a highly prevalent antigen. The present case highlights the same and different issues related to it. Read More

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http://www.ajts.org/text.asp?2017/11/2/195/214350
Publisher Site
http://dx.doi.org/10.4103/ajts.AJTS_76_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613430PMC
October 2017
20 Reads

Successful surgical procedure in a patient of aplastic anemia with platelet refractoriness, using cross-match compatible platelets.

Asian J Transfus Sci 2017 Jul-Dec;11(2):192-194

Department of Transfusion Medicine, Apollo Gleneagles Hospitals, Kolkata, West Bengal, India.

This case marks the beginning of issuing cross-matched platelet products in Eastern India. A known case of aplastic anemia, on regular transfusion support, now presented with obstructed ventral periumbilical hernia requiring urgent surgical intervention. Platelet count at presentation was 13,000/μL. Read More

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http://dx.doi.org/10.4103/ajts.AJTS_115_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613429PMC
October 2017
7 Reads