11,514 results match your criteria Asian cardiovascular & thoracic annals[Journal]


Association of QTc Interval with Risk of Cardiovascular Diseases and Related Vascular Traits: A Prospective and Longitudinal Analysis.

Glob Heart 2020 Feb 10;15(1):13. Epub 2020 Feb 10.

Shanghai National Clinical Research Center for Endocrine and Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, CH.

Background: Prolonged heart rate corrected QT (QTc) interval was reported to be associated with cardiovascular diseases (CVDs).

Objective: There exists little data on the association between QTc interval and cardiovascular risk in Asian populations. We prospectively investigated the association of QTc interval with CVDs and vascular traits in a large cohort of Chinese adults. Read More

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http://dx.doi.org/10.5334/gh.533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218767PMC
February 2020

[Phytochemical and pharmacological progress on genus Syringa].

Zhongguo Zhong Yao Za Zhi 2020 Apr;45(8):1833-1843

Modern Research Center for Traditional Chinese Medicine, School of Chinese Materia Medica,Beijing University of Chinese Medicine Beijing 100029, China.

The genus Syringa, belonging to the family Oleaceae, are distributed naturally in the European and Asian regions.This genus is composed of more than 20 species worldwide, among which about 16 species including 10 endemic ones are discovered in China.The Syringa sp. Read More

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http://dx.doi.org/10.19540/j.cnki.cjcmm.20200224.202DOI Listing

Prognostic impact of stress echocardiography with discordant stress electrocardiography in patients with suspected coronary artery disease.

Singapore Med J 2020 Mar;61(3):142-148

Department of Cardiology, Changi General Hospital, Singapore.

Introduction: During stress echocardiography, the echocardiologist routinely collects both echocardiographic images and stress electrocardiogram (ECG) concurrently. The managing physician faces a dilemma when the stress ECG and stress echocardiography results are discordant; for example, when a patient has negative stress echocardiography but positive stress ECG. We therefore sought to evaluate the prognostic value of stress echocardiography in relation to concordant or discordant stress ECG findings in our local Singapore setting, which has a well-defined Southeast Asian population. Read More

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http://dx.doi.org/10.11622/smedj.2019105DOI Listing

Intimal sarcoma of the pulmonary artery without F-fluorodeoxyglucose uptake.

Asian Cardiovasc Thorac Ann 2020 Jun 2:218492320932746. Epub 2020 Jun 2.

Department of Cardiovascular Surgery, Aomori Prefectural Central Hospital, Aomori, Japan.

Primary pulmonary intimal sarcoma is rare. Differentiating it from pulmonary thromboembolism is difficult because of similarities in clinical symptoms and imaging findings. Positron-emission tomography-computed tomography has been useful for diagnosing primary pulmonary intimal sarcoma. Read More

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http://dx.doi.org/10.1177/0218492320932746DOI Listing

Novel Insights into the Pathogenesis and Management of the Metabolic Syndrome.

Pediatr Gastroenterol Hepatol Nutr 2020 May 8;23(3):189-230. Epub 2020 May 8.

Department of Medicine and Genetics, Division of Gastroenterology and Liver Diseases, Marion Bessin Liver Research Center, Einstein-Mount Sinai Diabetes Research Center, Albert Einstein College of Medicine, Bronx, NY, USA.

The metabolic syndrome, by definition, is not a disease but is a clustering of individual metabolic risk factors including abdominal obesity, hyperglycemia, hypertriglyceridemia, hypertension, and low high-density lipoprotein cholesterol levels. These risk factors could dramatically increase the prevalence of type 2 diabetes and cardiovascular disease. The reported prevalence of the metabolic syndrome varies, greatly depending on the definition used, gender, age, socioeconomic status, and the ethnic background of study cohorts. Read More

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http://dx.doi.org/10.5223/pghn.2020.23.3.189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231748PMC

The association between daily naps and metabolic syndrome: Evidence from a population-based study in the Middle-East.

Sleep Health 2020 May 29. Epub 2020 May 29.

Department of Neurology, Mashhad University of Medical Sciences, Mashhad, Iran; Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada; Department of Clinical Neurological Sciences, Western University, London, Ontario, Canada; Stroke Prevention & Atherosclerosis Research Centre, Robarts Research Institute, Western University, London, Ontario, Canada. Electronic address:

Background: Daily naps are a common habit in many Middle Eastern and Asian countries; however, little is known about the association between daily naps and other health consequences, including the presence of metabolic syndrome (MetS).

Methods: Participants were recruited from the Mashhad stroke and heart atherosclerotic disorders study. We defined MetS according to International Diabetes Federation criteria. Read More

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http://dx.doi.org/10.1016/j.sleh.2020.03.007DOI Listing

Mitral valve perforation during transcatheter aortic valve replacement.

Asian Cardiovasc Thorac Ann 2020 Jun 1:218492320930842. Epub 2020 Jun 1.

Department of Cardiovascular Medicine, Nephrology and Neurology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.

An 86-year-old female with severe aortic valve stenosis underwent transcatheter aortic valve replacement. A balloon-expandable valve was used, guided by a double-stiff guidewire that successfully straightened the aorta. During valve placement, the balloon shifted. Read More

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http://dx.doi.org/10.1177/0218492320930842DOI Listing

Gamma-glutamyl transferase and cardiovascular risk in nonalcoholic fatty liver disease: The Gut and Obesity Asia initiative.

World J Gastroenterol 2020 May;26(19):2416-2426

Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.

Background: Gamma-glutamyl transferase (GGT) is associated with the risk of cardiovascular disease (CVD) in the general population.

Aim: To identify the association of baseline GGT level and QRISK2 score among patients with biopsy-proven nonalcoholic fatty liver disease (NAFLD).

Methods: This was a retrospective study involving 1535 biopsy-proven NAFLD patients from 10 Asian centers in 8 countries using data collected by the Gut and Obesity in Asia (referred to as "GO ASIA") workgroup. Read More

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http://dx.doi.org/10.3748/wjg.v26.i19.2416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243652PMC

Modest Sodium Reduction Increases Circulating Short-Chain Fatty Acids in Untreated Hypertensives: A Randomized, Double-Blind, Placebo-Controlled Trial.

Hypertension 2020 Jun 1:HYPERTENSIONAHA12014800. Epub 2020 Jun 1.

From the Department of Medicine, Georgia Prevention Institute, Medical College of Georgia, Augusta University, Augusta, GA (L.C., Y.D., Y.H., G.A.H., H.Z.).

High-sodium diet may modulate the gut microbiome. Given the circulating short-chain fatty acids (SCFAs) are microbial in origin, we tested the hypothesis that the modest sodium reduction would alter circulating SCFA concentrations among untreated hypertensives, and the changes would be associated with reduced blood pressure and improved cardiovascular phenotypes. A total of 145 participants (42% blacks, 19% Asian, and 34% females) were included from a randomized, double-blind, placebo-controlled cross-over trial of sodium reduction with slow sodium or placebo tablets, each for 6 weeks. Read More

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.120.14800DOI Listing

Association Between Sarcopenia and Quality of Life in Patients with Early Dementia and Mild Cognitive Impairment.

J Alzheimers Dis 2020 May 26. Epub 2020 May 26.

Department of Community Healthcare and Geriatrics, Nagoya University Graduate School of Medicine, Aichi, Japan.

Background: Cognitive impairment is linked to decreased quality of life (QOL), but few studies have investigated the impact of comorbid sarcopenia.

Objective: The aim of this study was to elucidate the association of sarcopenia with QOL in patients with early dementia and mild cognitive impairment.

Methods: Individuals with a Clinical Dementia Rating of 0. Read More

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http://dx.doi.org/10.3233/JAD-200169DOI Listing

Frequency of Management of Cardiogenic Shock With Mechanical Circulatory Support Devices According to Race.

Am J Cardiol 2020 Jun 6;125(12):1782-1787. Epub 2020 Apr 6.

Division of Cardiovascular Medicine, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut.

Mechanical circulatory support (MCS) has influenced the management of cardiogenic shock (CS), but the association between race and MCS utilization is unknown. We sought to evaluate the effect of race on MCS utilization in CS and whether there are racial differences in in-hospital outcomes. Our study was a population-based retrospective cohort study that enrolled patients with CS, defined by International classification of disease, ninth Revision, clinical modification (ICD-9-CM) codes, between 2013 and 2015 from the National Inpatient Sample. Read More

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http://dx.doi.org/10.1016/j.amjcard.2020.03.025DOI Listing

Challenges and experience of setting up an aortic service.

Asian Cardiovasc Thorac Ann 2020 May 29:218492320930841. Epub 2020 May 29.

Heart Valve Disease Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.

Aortic surgery is a complex procedure posing high risks in comparison to other adult cardiac surgeries. Novel surgical approaches including minimally invasive procedures, sutureless aortic valve replacement, and transcatheter aortic valve implantation have been found to be acceptable alternatives to conventional surgeries. In addition, novel endovascular repair techniques and hybrid procedures have been introduced for the management of patients with thoracoabdominal aortic pathologies. Read More

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http://dx.doi.org/10.1177/0218492320930841DOI Listing

A unique "uncorrected" configuration of levo-transposition of the great arteries.

Asian Cardiovasc Thorac Ann 2020 May 29:218492320931224. Epub 2020 May 29.

Department of Cardiovascular Radiology & Endovascular Interventions, All India Institute of Medical Sciences, New Delhi, India.

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http://dx.doi.org/10.1177/0218492320931224DOI Listing

Perspectives on surgical treatment of mitral valve disease.

Authors:
Tirone E David

Asian Cardiovasc Thorac Ann 2020 May 29:218492320930846. Epub 2020 May 29.

Division of Cardiovascular Surgery of Peter Munk Cardiac Centre at Toronto General Hospital and the University of Toronto, Toronto, Ontario, Canada.

A sound knowledge of the functional anatomy of the mitral valve and the alterations caused by different diseases is indispensable for surgeons treating patients with mitral valve disease. Rheumatic mitral valve disease remains the most common heart valvular disorder in developing countries, whereas mitral regurgitation due myxomatous degeneration of the valve is the most common in developed countries. The mitral valve should be repaired whenever possible, as long as the outcome is predictably better than that of replacement. Read More

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http://dx.doi.org/10.1177/0218492320930846DOI Listing

Transethnic Meta-analysis of Genome-wide Association Studies Identifies Three New Loci and Characterizes Population-specific Differences for Coronary Artery Disease.

Circ Genom Precis Med 2020 May 29. Epub 2020 May 29.

Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

- Genome-wide association studies (GWAS) provided many biological insights into coronary artery disease (CAD), but these studies were mainly performed in Europeans. GWAS in diverse populations have the potential to advance our understanding of CAD. - We conducted two GWAS for CAD in the Japanese population, which included 12,494 cases and 28,879 controls, and 2,808 cases and 7,261 controls, respectively. Read More

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http://dx.doi.org/10.1161/CIRCGEN.119.002670DOI Listing

Ethnic and socioeconomic differences in SARS-CoV-2 infection: prospective cohort study using UK Biobank.

BMC Med 2020 05 29;18(1):160. Epub 2020 May 29.

MRC/CSO Social & Public Health Sciences Unit, University of Glasgow, Top floor, 200 Renfield Street, Glasgow, G2 3QB, UK.

Background: Understanding of the role of ethnicity and socioeconomic position in the risk of developing SARS-CoV-2 infection is limited. We investigated this in the UK Biobank study.

Methods: The UK Biobank study recruited 40-70-year-olds in 2006-2010 from the general population, collecting information about self-defined ethnicity and socioeconomic variables (including area-level socioeconomic deprivation and educational attainment). Read More

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http://dx.doi.org/10.1186/s12916-020-01640-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255908PMC

Global cardiovascular care: an overview of high-level political commitment.

Asian Cardiovasc Thorac Ann 2020 May 27:218492320930844. Epub 2020 May 27.

Division of Cardiovascular Surgery, Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Background: Six billion people worldwide lack access to safe, timely, and affordable cardiac surgical and interventional care when needed. Cardiovascular diseases are the leading cause of mortality and morbidity around the world, and include a significant surgical backlog of rheumatic and congenital heart diseases. Here, we review the political commitment by the WHO, the UN, and the World Bank to build and strengthen healthcare services for cardiovascular diseases, with a particular focus on cardiac surgical and interventional cardiology services around the world. Read More

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http://dx.doi.org/10.1177/0218492320930844DOI Listing

Association of antipsychotics adherence and cardiovascular disease among newly diagnosed schizophrenia patients: A national cohort among Koreans.

Asian J Psychiatr 2020 May 12;52:102161. Epub 2020 May 12.

Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, South Korea; Department of Family Medicine, Seoul National University Hospital, 127, Yongmasan-ro, Gwangjin-gu, Seoul, South Korea. Electronic address:

Background: The effect of antipsychotics adherence on the risk of cardiovascular disease (CVD) among schizophrenia patients has not been studied. While antipsychotic adherence is favorable for all-cause mortality, its association with CVD incidence is unclear due to the potential risk of CVD caused by antipsychotics.

Methods: Using the Korean National Health Insurance Service Database, we constructed a case-cohort of 80,581 newly-diagnosed schizophrenia patients between 2004 and 2013 from a cohort of all Koreans 20-40 years old. Read More

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http://dx.doi.org/10.1016/j.ajp.2020.102161DOI Listing

Egg consumption and risk of type 2 diabetes: findings from 3 large US cohort studies of men and women and a systematic review and meta-analysis of prospective cohort studies.

Am J Clin Nutr 2020 May 26. Epub 2020 May 26.

Department of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA.

Background: Whether egg consumption is associated with the risk of type 2 diabetes (T2D) remains unsettled.

Objectives: We evaluated the association between egg consumption and T2D risk in 3 large US prospective cohorts, and performed a systematic review and meta-analysis of prospective cohort studies.

Methods: We followed 82,750 women from the Nurses' Health Study (NHS; 1980-2012), 89,636 women from the NHS II (1991-2017), and 41,412 men from the Health Professionals Follow-up Study (HPFS; 1986-2016) who were free of T2D, cardiovascular disease, and cancer at baseline. Read More

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http://dx.doi.org/10.1093/ajcn/nqaa115DOI Listing

Ascending aorta mechanics in bicuspid aortopathy: controversy or fact?

Asian Cardiovasc Thorac Ann 2020 May 25:218492320928731. Epub 2020 May 25.

Biomechanics Laboratory, Center of Clinical, Experimental Surgery, and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece.

Bicuspid aortic valve is the most common congenital cardiovascular defect, often associated with proximal aortic dilatation, and the ideal management strategy is debated. The inconsistency in previous and present guideline recommendations emphasizes the insufficiency of the maximal diameter as the sole criterion for prophylactic repair. Our ability to guide clinical decisions may improve through an understanding of the mechanical properties of ascending thoracic aortic aneurysms in bicuspid compared to tricuspid aortic valve patients and non-aneurysmal aortas, because dissection and rupture are aortic wall mechanical failures. Read More

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http://dx.doi.org/10.1177/0218492320928731DOI Listing

Factor analyses of metabolic syndrome: A systematic review with special reference to Asian Indians.

Diabetes Metab Syndr 2020 May 11;14(4):697-705. Epub 2020 May 11.

Biomedical Research Laboratory, Department of Anthropology, Visva-Bharati (A Central University and an Institution of National Importance), Santiniketan, West Bengal, India. Electronic address:

Background: Metabolic syndrome is the constellation of cardiovascular disease risk factors and a growing public health issue affecting more than 20% of world population. Factor analysis is a powerful mathematical tool in exploring the underlying factors of any chronic diseases. Although it is most often criticized for its contrasting results for a common expression differently interpreted by the researchers yet fit the original data equally well. Read More

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http://dx.doi.org/10.1016/j.dsx.2020.05.014DOI Listing

Health Care Costs Associated With Macrovascular, Microvascular, and Metabolic Complications of Type 2 Diabetes Across Time: Estimates From a Population-Based Cohort of More Than 0.8 Million Individuals With Up to 15 Years of Follow-up.

Diabetes Care 2020 May 22. Epub 2020 May 22.

Institute of Clinical Pharmacy and Pharmaceutical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan

Objective: Developing country-specific unit-cost catalogs is a key area for advancing economic research to improve medical and policy decisions. However, little is known about how health care costs vary by type 2 diabetes (T2D) complications across time in Asian countries. We sought to quantify the economic burden of various T2D complications in Taiwan. Read More

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http://dx.doi.org/10.2337/dc20-0072DOI Listing

Reference Ranges for Left Ventricular Curvedness and Curvedness-Based Functional Indices Using Cardiovascular Magnetic Resonance in Healthy Asian Subjects.

Sci Rep 2020 May 21;10(1):8465. Epub 2020 May 21.

National Heart Research Institute Singapore, National Heart Centre Singapore, 5 Hospital Drive, Singapore, 169609, Singapore.

Curvature-based three-dimensional cardiovascular magnetic resonance (CMR) allows regional function characterization without an external spatial frame of reference. However, introduction of this modality into clinical practice is hampered by lack of reference values. We aim to establish normal ranges for 3D left ventricular (LV) regional parameters in relation to age and gender for 171 healthy subjects. Read More

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http://dx.doi.org/10.1038/s41598-020-65153-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242400PMC

Personalized neoantigen-based immunotherapy for advanced collecting duct carcinoma: case report.

J Immunother Cancer 2020 May;8(1)

The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, China

Background: Collecting duct carcinoma (CDC) of the kidney is a rare and highly aggressive malignant tumor with the worst prognosis among all renal cancers. Nevertheless, the first-line treatments, including chemotherapy and target therapy, usually show poor response to CDC. Recent studies have suggested that immunotherapy targeting personal tumor-specific neoantigens could be a promising strategy for several solid cancers. Read More

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http://dx.doi.org/10.1136/jitc-2019-000217DOI Listing

Associations between reproductive factors and biliary tract cancers in women from the Biliary Tract Cancers Pooling Project.

J Hepatol 2020 May 10. Epub 2020 May 10.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.

Background: Gallbladder cancer (GBC) has a female predominance, although other biliary tract cancers (BTCs) such as extrahepatic and intrahepatic bile duct (EHBDC and IHBDC) and ampulla of Vater (AVC) have a male predominance. The role of female reproductive factors in BTC etiology remains unclear.

Methods: We pooled data from 19 studies of >1. Read More

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http://dx.doi.org/10.1016/j.jhep.2020.04.046DOI Listing

Endo-Bentall for proximal aortic dissection: from conception to application.

Asian Cardiovasc Thorac Ann 2020 May 21:218492320929211. Epub 2020 May 21.

Department of Cardiovascular Surgery, Heart Centre Freiburg University, Freiburg, Germany.

The endovascular treatment of pathologies of the ascending aorta has not been incorporated into routine clinical practice. The aim of this article is to provide an overview of the endovascular treatment of pathologies of the ascending aorta, particularly type A aortic dissection. A thorough analysis and discussion of anatomical, physiological, clinical and technical challenges, and obstacles is performed. Read More

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http://dx.doi.org/10.1177/0218492320929211DOI Listing

Age-, sex- and ethnicity-related differences in body weight, blood pressure, HbA and lipid levels at the diagnosis of type 2 diabetes relative to people without diabetes.

Diabetologia 2020 May 21. Epub 2020 May 21.

Institute of Cardiovascular & Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, 126 University Place, Glasgow, G12 8TA, UK.

Aims/hypothesis: The aim of this work was to determine how weight patterns together with blood glucose, BP and lipids vary at diagnosis of diabetes by age, sex and ethnicity.

Methods: Using the UK Clinical Practice Research Datalink, we identified people with type 2 diabetes (n = 187,601) diagnosed in 1998-2015 and compared their weights, HbA, BP and lipid levels at diagnosis with age-matched people without diabetes (n = 906,182), by sex and ethnic group.

Results: Younger age at diagnosis was associated with greater adjusted mean difference (95% CI) in weight between those with vs without type 2 diabetes: 18. Read More

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http://dx.doi.org/10.1007/s00125-020-05169-6DOI Listing

Resting heart rate control and prognosis in coronary artery disease patients with hypertension previously treated with bisoprolol: a sub-group analysis of the BISO-CAD study.

Chin Med J (Engl) 2020 May;133(10):1155-1165

Department of Cardiology, Sejong Hospital, Gyeonggi-do 14754, Korea.

Background: Resting heart rate (RHR) is considered as a strong predictor of total mortality and hospitalization due to heart failure in hypertension patients. Bisoprolol fumarate, a second-generation beta-adrenoreceptor blockers (β-blocker) is commonly prescribed drug to manage hypertension. The present study was to retrospectively evaluate changes in the average RHR and its association with cardiovascular outcomes in bisoprolol-treated coronary artery disease (CAD) patients from the CAD treated with bisoprolol (BISO-CAD) study who had comorbid hypertension. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000802DOI Listing

Ten-Year Trends in Enrollment of Women and Minorities in Pivotal Trials Supporting Recent US Food and Drug Administration Approval of Novel Cardiometabolic Drugs.

J Am Heart Assoc 2020 Jun 19;9(11):e015594. Epub 2020 May 19.

Division of Cardiology Johns Hopkins Ciccarone Center for the Prevention of Cardiovascular Disease Baltimore MD.

Background In 1993, the US Food and Drug Administration established guidelines to increase diversity by sex and race/ethnicity of participants in clinical trials supporting novel drug approvals. In this study we investigated the 10-year trends of participation of women and minorities in pivotal trials supporting approval of new molecular entities in cardiometabolic drugs from January 2008 to December 2017. Methods and Results A list of new molecular entities was abstracted from publicly available data at Drugs@Fda. Read More

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http://dx.doi.org/10.1161/JAHA.119.015594DOI Listing

Epidemiological profile and management patterns of acute myocardial infarction in very young patients from a tertiary care center.

Indian Heart J 2020 Jan - Feb;72(1):32-39. Epub 2020 Mar 24.

Department of Cardiology, G B Pant Institute of Post Graduate Medical Education and Research, New Delhi, India.

Background: Cardiovascular disease is the leading cause of death in India. Previously it was thought to be a disease of the elderly but now an epidemiological transition is being seen with increasing incidence in the very young adults as well. Such patterns are not well studied in the South East Asian population. Read More

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http://dx.doi.org/10.1016/j.ihj.2020.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231868PMC

Surgical excision of an epicardial ventricular hydatid cyst.

Asian Cardiovasc Thorac Ann 2020 May 16:218492320927200. Epub 2020 May 16.

Department of Cardiothoracic Surgery and Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bangalore, India.

Isolated cardiac hydatid cyst is a rare entity. It warrants early surgical repair because cyst rupture is potentially fatal. We report the case of a 32-year-old lady with an epicardial ventricular hydatid cyst, which was managed successfully by complete cyst excision. Read More

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http://dx.doi.org/10.1177/0218492320927200DOI Listing

Incidence of urticaria, angioedema, and type I hypersensitivity reactions associated with fibrinolytic agents in Thailand using the database of the health product vigilance center.

Asian Pac J Allergy Immunol 2020 May 17. Epub 2020 May 17.

Health Product Vigilance Center, Technical and Planning Division, Food and Drug Administration, Ministry of Public Health, Thailand.

Background: Besides hemorrhage, allergic reactions have also been observed in several clinical trials of fibrinolytic agents. These reactions might negatively affect patient outcomes, especially life-threatening type I hypersensitivity reactions such as anaphylaxis. However, there are limited data on the incidence of these reactions. Read More

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http://dx.doi.org/10.12932/AP-181119-0694DOI Listing

Anticoagulation control in different ethnic groups receiving vitamin K antagonist therapy for stroke prevention in atrial fibrillation.

Thromb Res 2020 May 6;192:12-20. Epub 2020 May 6.

Liverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool, United Kingdom; Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. Electronic address:

Background: Efficacy and safety of vitamin K antagonists (VKAs) is optimised in atrial fibrillation (AF) patients when the International Normalised Ratio (INR) is 2.0-3.0. Read More

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http://dx.doi.org/10.1016/j.thromres.2020.04.001DOI Listing

Knowledge of Heart Disease, Preventive Behavior and Source of Information in a Multi-ethnic Asian Population: A Population-Based Survey.

J Community Health 2020 May 15. Epub 2020 May 15.

Health Services and Systems Research, Duke-NUS Medical School, Singapore, Singapore.

Several population-based studies have been conducted to better understand the public knowledge of cardiovascular disease (CVD) and behavior. However, most studies have predominantly focused on Western populations. This study aimed to investigate heart disease knowledge, preventive behavior and source of information on heart disease in a multi-ethnic Asian population. Read More

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http://dx.doi.org/10.1007/s10900-020-00838-4DOI Listing

Vitamin D concentrations and COVID-19 infection in UK Biobank.

Diabetes Metab Syndr 2020 May 7;14(4):561-565. Epub 2020 May 7.

Institute of Health and Wellbeing, University of Glasgow, 1 Lilybank Gardens, Glasgow, G12 8RZ, UK. Electronic address:

Background And Aims: COVID-19 and low levels of vitamin D appear to disproportionately affect black and minority ethnic individuals. We aimed to establish whether blood 25-hydroxyvitamin D (25(OH)D) concentration was associated with COVID-19 risk, and whether it explained the higher incidence of COVID-19 in black and South Asian people.

Methods: UK Biobank recruited 502,624 participants aged 37-73 years between 2006 and 2010. Read More

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http://dx.doi.org/10.1016/j.dsx.2020.04.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204679PMC

Ethnic disparities in initiation and intensification of diabetes treatment in adults with type 2 diabetes in the UK, 1990-2017: A cohort study.

PLoS Med 2020 May 15;17(5):e1003106. Epub 2020 May 15.

Department of Non-communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, United Kingdom.

Background: Type 2 diabetes mellitus (T2DM) disproportionately affects individuals of nonwhite ethnic origin. Timely and appropriate initiation and intensification of glucose-lowering therapy is key to reducing the risk of major vascular outcomes. Given that ethnic inequalities in outcomes may stem from differences in therapeutic management, the aim of this study was to identify ethnic differences in the timeliness of initiation and intensification of glucose-lowering therapy in individuals newly diagnosed with T2DM in the United Kingdom. Read More

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http://dx.doi.org/10.1371/journal.pmed.1003106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228040PMC

Cardiological society of India position statement on COVID-19 and heart failure.

Indian Heart J 2020 May 13. Epub 2020 May 13.

C.K. Birla Group of Hospitals (BMB/CMRI), Kolkata.

The COVID 19 global pandemic has engulfed humanity with a huge impact on health systems across the world. Many patients develop myocardial injury which can lead to significant cardiovascular complications including HF. This will require aggressive management strategies which are evolving. Read More

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http://dx.doi.org/10.1016/j.ihj.2020.04.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219407PMC

Progress on sodium reduction in South Korea.

BMJ Glob Health 2020 May;5(5)

Executive Director, Korea Health Industry Development Institute, Cheongju, Republic of Korea

Introduction: High dietary sodium is a leading contributor to hypertension, and hypertension is the leading underlying cause of death globally. There is a robust body of evidence supporting the health benefits of sodium reduction. Sodium intake in South Korea is high, with about half the population consuming 4000 mg/day, twice the recommended upper limit. Read More

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http://dx.doi.org/10.1136/bmjgh-2019-002028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228482PMC

Association of Prediabetes and Type 2 Diabetes With Cognitive Function After Stroke: A STROKOG Collaboration Study.

Stroke 2020 Jun 14;51(6):1640-1646. Epub 2020 May 14.

From the Centre for Healthy Brain Ageing (CHeBA), School of Psychiatry, UNSW Sydney, Australia (J.W.L., J.D.C., R.J.C., D.M.L., P.S.S.).

Background and Purpose- Type 2 diabetes mellitus (T2D) is associated with cognitive impairment and an increased risk of dementia, but the association between prediabetes and cognitive impairment is less clear, particularly in a setting of major cerebrovascular events. This article examines the impact of impaired fasting glucose and T2D on cognitive performance in a stroke population. Methods- Seven international observational studies from the STROKOG (Stroke and Cognition) consortium (n=1601; mean age, 66. Read More

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http://dx.doi.org/10.1161/STROKEAHA.119.028428DOI Listing

Defibrillation threshold testing during implantable cardioverter defibrillator implantation: 5-year follow-up.

J Interv Card Electrophysiol 2020 May 13. Epub 2020 May 13.

Department of Cardiovascular Medicine, Chonnam National University Medical School, 42, Jebong-ro, Dong-gu, Gwangju, 61469, South Korea.

Purpose: Defibrillation threshold (DFT) testing is a routine practice in some Asian countries for patients receiving an implantable cardioverter defibrillator (ICD). However, there are few long-term data about the necessity of intraoperative DFT testing in an Asian population. We investigated the safety of DFT testing and the long-term clinical outcomes in Asian patients undergoing ICD implantation. Read More

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http://dx.doi.org/10.1007/s10840-020-00733-xDOI Listing
May 2020
1.552 Impact Factor

Relationship Between Platelet Reactivity and Ischemic and Bleeding Events After Percutaneous Coronary Intervention in East Asian Patients: 1-Year Results of the PENDULUM Registry.

J Am Heart Assoc 2020 May 12;9(10):e015439. Epub 2020 May 12.

Department of Medical Statistics School of Medicine Toho University Tokyo Japan.

Background The balance between ischemic and bleeding events and their association with platelet reactivity in patients receiving antiplatelet therapy after percutaneous coronary intervention (PCI), which differs among regions, is not fully evaluated for East Asians. We examined ischemic/bleeding events and platelet reactivity in Japanese patients undergoing PCI and determined associations between high/low platelet reactivity and clinical outcomes. Methods and Results PENDULUM (Platelet Reactivity in Patients with Drug Eluting Stent and Balancing Risk of Bleeding and Ischemic Event) is a prospective, multicenter registry of Japanese patients with PCI. Read More

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http://dx.doi.org/10.1161/JAHA.119.015439DOI Listing

Adherence to Anticoagulant Guideline for Atrial Fibrillation Improves Outcomes in Asian Population: The COOL-AF Registry.

Stroke 2020 Jun 11;51(6):1772-1780. Epub 2020 May 11.

Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, United Kingdom (G.Y.H.L.).

Background and Purpose- Guideline adherent oral anticoagulant (OAC) management of patients with nonvalvular atrial fibrillation has been associated with improved outcomes, but limited data are available from Asia. We aimed to investigate outcomes in patients who received guideline compliant management compared with those who were OAC undertreated or overtreated, in a large nationwide multicenter cohort of patients with nonvalvular atrial fibrillation in Thailand. Methods- Patients with nonvalvular atrial fibrillation were prospectively enrolled from 27 hospitals-all of which are data contributors to the COOL-AF Registry (Cohort of Antithrombotic Use and Optimal INR Level in Patients With Non-Valvular Atrial Fibrillation in Thailand). Read More

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http://dx.doi.org/10.1161/STROKEAHA.120.029295DOI Listing

Heterogeneity of Treatment and Outcomes Among Asians With Coronary Artery Disease in the United States.

J Am Heart Assoc 2020 May 11;9(10):e014362. Epub 2020 May 11.

Division of Cardiology Stanford University Stanford CA.

Background Prior data demonstrate significant heterogeneity regarding coronary artery disease risk factors and outcomes among Asians in the United States, but no studies have yet examined coronary artery disease treatment patterns or outcomes among disaggregated Asian American subgroups. Methods and Results From a total of 772 882 patients with known race/ethnicity and sex who received care from a mixed-payer healthcare organization in Northern California between 2006 and 2015, a retrospective analysis was conducted on 6667 adults with coronary artery disease. Logistic regression was used to examine medical and procedural therapies and outcomes by race/ethnicity, with adjustment for age, sex, income, and baseline comorbidities. Read More

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http://dx.doi.org/10.1161/JAHA.119.014362DOI Listing

Insights into pharmacological mechanisms of polydatin in targeting risk factors-mediated atherosclerosis.

Life Sci 2020 May 7;254:117756. Epub 2020 May 7.

IIRC-5, Clinical Biochemistry and Natural Product Research Lab, Department of Biosciences, Integral University, Lucknow 226026, U.P., India. Electronic address:

Polydatin (PD) is a monocrystalline metabolite from the underground parts of Polygonum cuspidatum Sieb. et Zucc., a member of the Polygonaceae family, which has been traditionally used in Asian countries as both foodstuffs and medicine. Read More

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http://dx.doi.org/10.1016/j.lfs.2020.117756DOI Listing
May 2020
2.702 Impact Factor

Two-year outcomes post-discharge in Asian patients with acute coronary syndrome: Findings from the EPICOR Asia study.

Int J Cardiol 2020 May 7. Epub 2020 May 7.

Sarawak General Hospital, Kuching, Malaysia.

Aims: Approximately half of cases of cardiovascular disease (CVD) worldwide occur in Asia, with acute coronary syndrome (ACS) a leading cause of mortality. Long-term ACS-related outcomes data in Asia are limited. This analysis examined 2-year ACS-related outcomes in patients enrolled in the EPICOR Asia study, and the association between patient characteristics and management on outcomes. Read More

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http://dx.doi.org/10.1016/j.ijcard.2020.05.022DOI Listing
May 2020
4.036 Impact Factor

Recent advances and controversies in surgical intervention of nontuberculous mycobacterial lung disease: A literature review.

J Formos Med Assoc 2020 May 6. Epub 2020 May 6.

Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan; Thoracic Medicine Center, Department of Medicine and Surgery, National Taiwan University Hospital Yunlin Branch, Yunlin County, Taiwan. Electronic address:

The prevalence of nontuberculous mycobacterial lung disease (NTM-LD) has increased in Western and Asian nations in recent decades. While surgery may improve the outcome of more complex cases, many inconsistencies exist in the current literature regarding the management, growing emergence, and challenges of drug-resistant forms of NTM-LD, the indications and timing of surgical treatment, and perioperative multimodal therapy of NTM-LD. Moreover, data regarding the comparative treatments, risk factors of pulmonary resection for NTM-LD, and the long-term outcomes of microbiological recurrence are limited. Read More

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http://dx.doi.org/10.1016/j.jfma.2020.04.029DOI Listing

Risk factors of white matter hyperintensities in South Asian patients with transient ischemic attack and minor stroke.

Neuroradiology 2020 May 9. Epub 2020 May 9.

Comprehensive Stroke Care Program, Department of Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Thiruvananthapuram, Kerala, 695011, India.

Purpose: Aging and increased burden of cardiovascular risk factors are associated with severity of white matter hyperintensity (WMH). We assessed the burden and risk factor profile of WMHs in South Asian patients with transient ischemic attack (TIA) and minor stroke.

Methods: Patients with acute ischemic stroke with the National Institute of Health stroke scale (NIHSS) score ≤ 5 who underwent MRI were included. Read More

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http://dx.doi.org/10.1007/s00234-020-02429-5DOI Listing

Comparison between ticagrelor versus clopidogrel in long term outcomes of Taiwanese diabetic subjects with acute coronary syndrome undergoing successful revascularization: From TSOC ACS-DM registry.

Medicine (Baltimore) 2020 May;99(19):e19969

Division of Cardiovascular Medicine, Department of Internal Medicine, Taipei Municipal Wan-Fang Hospital, Taipei.

Although previous clinical trials demonstrated that ticagrelor could reduce cardiovascular events and mortality versus clopidogrel in patients with acute coronary syndrome (ACS), the real-world evidence of its clinical impacts on East Asian Diabetic population has rarely been investigated.Between November 2013 and June 2015, 1534 patients were recruited into the Acute Coronary Syndrome-Diabetes Mellitus Registry of the Taiwan Society of Cardiology (TSOC ACS-DM registry). After propensity score matching, a total of 730 patients undergoing successful revascularization and discharged on ticagrelor (N = 365) or clopidogrel (N = 365) were analyzed. Read More

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http://dx.doi.org/10.1097/MD.0000000000019969DOI Listing

Successful management of Klippel-Trenaunay syndrome in a pregnant Asian woman: A case report.

Medicine (Baltimore) 2020 May;99(19):e19932

Department of Obstetrics and Gynecology, West China Second University Hospital of Sichuan University.

Rationale: Klippel-Trenaunay Syndrome (KTS) is a congenital vascular disease characterized by cutaneous hemangiomas, venous varicosities, and limb hypertrophy. Although extremely rare in pregnant women, the present vascular alterations may be aggravated, consequent to postural and hormonal changes inherent to the pregnancy. Pregnancy is not advised in KTS women due to increased obstetrical risk. Read More

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http://dx.doi.org/10.1097/MD.0000000000019932DOI Listing